## Sat Jan  4 13:04:41 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA298972/SRR2844601/SRR2844601_p_cluster_rep_seq.fasta --output PRJNA298972_SRR2844601 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_740193_1	1250006.JHZZ01000001_gene2154	2.26e-118	359.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1I02Y@117743|Flavobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
k59_5771_1	563040.Saut_1247	3.67e-64	200.0	COG1149@1|root,COG1149@2|Bacteria,1QZ2E@1224|Proteobacteria,42TQN@68525|delta/epsilon subdivisions,2YPUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ferredoxin-type protein NapF	napF	-	-	ko:K02572	-	-	-	-	ko00000	-	-	-	Fer4
k59_5771_2	929558.SMGD1_0594	6.27e-37	135.0	COG3391@1|root,COG3391@2|Bacteria,1QUIK@1224|Proteobacteria,42RTQ@68525|delta/epsilon subdivisions,2YPA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	amine dehydrogenase activity	napL	-	-	-	-	-	-	-	-	-	-	-	-
k59_288486_1	1197477.IA57_08930	4.65e-51	171.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1HYAP@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_288486_2	1380600.AUYN01000009_gene1697	5e-35	126.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1HX31@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_175764_1	90814.KL370891_gene1183	1.13e-97	298.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,4605R@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_175764_2	1123518.ARWI01000001_gene97	6.66e-13	62.8	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	yfhL	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_1644289_1	945713.IALB_2373	1.99e-73	232.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_1248092_1	293826.Amet_0510	8.94e-33	129.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,36ED9@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1248095_1	76114.ebA4317	6.49e-106	321.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VMX6@28216|Betaproteobacteria,2KVNW@206389|Rhodocyclales	206389|Rhodocyclales	H	Capsular polysaccharide biosynthesis protein CapK	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_344430_1	1137281.D778_02395	1.31e-51	176.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,1HWMR@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_344430_2	983544.Lacal_0579	8.8e-46	159.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1135452_2	944547.ABLL_0490	4.28e-57	186.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,42NMJ@68525|delta/epsilon subdivisions,2YMIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin-type protein, NapH MauN family	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_6
k59_1078538_1	1121897.AUGO01000015_gene3392	5.09e-14	67.0	2C9B9@1|root,32RP0@2|Bacteria,4NSK0@976|Bacteroidetes,1I3XD@117743|Flavobacteriia,2NWSM@237|Flavobacterium	976|Bacteroidetes	S	type III effector	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
k59_1078538_2	1168067.JAGP01000001_gene1070	3.44e-69	216.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,46091@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_288520_1	1042376.AFPK01000044_gene2588	7.59e-11	64.3	COG3119@1|root,COG3119@2|Bacteria,4NGCH@976|Bacteroidetes,1IIHB@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_344437_1	90814.KL370891_gene584	1.16e-48	167.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_344437_2	90814.KL370891_gene583	1.1e-45	149.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales	72273|Thiotrichales	H	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_344437_3	1123514.KB905899_gene1534	2.83e-103	306.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,4602K@72273|Thiotrichales	72273|Thiotrichales	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_513987_2	1123518.ARWI01000001_gene1269	9.17e-70	222.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,45ZZP@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_175811_1	1348635.BBJY01000005_gene3361	2.44e-13	72.0	2AW29@1|root,31MX0@2|Bacteria,1QJP1@1224|Proteobacteria,1THPY@1236|Gammaproteobacteria,1XX3X@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1305728_1	313598.MED152_05625	4.61e-41	141.0	COG0546@1|root,COG0546@2|Bacteria,4NN2C@976|Bacteroidetes,1I1WE@117743|Flavobacteriia,3VX7F@52959|Polaribacter	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1587982_1	1499967.BAYZ01000160_gene409	2.87e-26	100.0	COG3668@1|root,COG3668@2|Bacteria,2NRK1@2323|unclassified Bacteria	2|Bacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_1587982_2	765911.Thivi_1781	4.2e-14	66.6	2DPTZ@1|root,333CW@2|Bacteria,1NE58@1224|Proteobacteria,1SG82@1236|Gammaproteobacteria,1X20I@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118936_1	655815.ZPR_1491	1.85e-129	382.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HWSK@117743|Flavobacteriia	976|Bacteroidetes	E	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
k59_684338_1	929558.SMGD1_2173	4.31e-114	341.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2YMT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1248133_1	1123514.KB905902_gene244	6.62e-65	211.0	COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1248133_2	1123514.KB905902_gene245	2.39e-15	74.7	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,45ZQH@72273|Thiotrichales	72273|Thiotrichales	E	peptidase	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1078569_1	572480.Arnit_2745	2.09e-138	401.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2YMCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_288546_1	1380600.AUYN01000009_gene1904	2.09e-47	169.0	2A0VS@1|root,30P0U@2|Bacteria,4NPP3@976|Bacteroidetes,1I29C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1360980_1	391603.FBALC1_09667	3.66e-124	367.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_797075_1	765911.Thivi_0648	3.35e-115	354.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WWRT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_684343_1	998674.ATTE01000001_gene2162	2.14e-47	173.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,1SAZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_684343_2	1392489.JPOL01000002_gene3364	2.91e-10	60.1	COG0438@1|root,COG0438@2|Bacteria,4NGDA@976|Bacteroidetes,1HY6S@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_1135492_1	1336233.JAEH01000011_gene2875	1.43e-63	204.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,2Q9BB@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	yggW	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1135492_2	1565129.JSFF01000016_gene215	2.18e-52	170.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,2QAF0@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
k59_1474386_1	1123518.ARWI01000001_gene2447	1.08e-114	333.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	sirR	-	-	ko:K03709,ko:K04758,ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.15	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k59_1248139_1	326298.Suden_1092	8.41e-55	177.0	COG0666@1|root,COG0666@2|Bacteria,1Q2UY@1224|Proteobacteria,42WAJ@68525|delta/epsilon subdivisions,2YQKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_1248139_2	563040.Saut_1204	7.79e-158	451.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,42MHI@68525|delta/epsilon subdivisions,2YMU8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k59_1135494_1	411154.GFO_2084	2.2e-126	372.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1HXUH@117743|Flavobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_232358_1	1121912.AUHD01000006_gene1406	1.24e-89	270.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1HX5W@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_1588006_1	1380600.AUYN01000006_gene575	3.25e-94	282.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_344476_1	1336803.PHEL49_2234	7.5e-108	321.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,1I0SF@117743|Flavobacteriia,3VW3Q@52959|Polaribacter	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
k59_118953_1	396588.Tgr7_3228	1.72e-08	57.8	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1WZQB@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
k59_118953_2	330214.NIDE4094	0.000948	46.6	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
k59_458305_1	983544.Lacal_0142	4.89e-157	449.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1HWNS@117743|Flavobacteriia	976|Bacteroidetes	E	periplasmic protein kinase ArgK and related	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_458305_2	867900.Celly_2766	5.71e-103	306.0	COG1215@1|root,COG1215@2|Bacteria,4NJ55@976|Bacteroidetes,1IJK8@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_458305_3	1086011.HJ01_02494	3.33e-184	530.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1HZ2M@117743|Flavobacteriia,2NXMH@237|Flavobacterium	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
k59_1190791_2	929558.SMGD1_0904	7.83e-51	177.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_740283_1	1355374.JARU01000001_gene210	6.17e-09	56.6	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_740283_2	1341155.FSS13T_05820	5.34e-05	45.4	COG0492@1|root,COG0492@2|Bacteria,4NHKD@976|Bacteroidetes,1I1D6@117743|Flavobacteriia,2NT04@237|Flavobacterium	976|Bacteroidetes	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_1474404_1	1121931.AUHG01000011_gene1779	1.15e-134	393.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1HY1F@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
k59_1078599_2	929558.SMGD1_0822	2.22e-162	459.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2YN4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_1078601_1	504487.JCM19302_735	9.95e-115	335.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_1757404_1	1123518.ARWI01000001_gene242	2.3e-130	393.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1135523_1	1178825.ALIH01000016_gene620	2.28e-07	52.8	COG1086@1|root,COG1086@2|Bacteria,4P0C8@976|Bacteroidetes,1I7GZ@117743|Flavobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
k59_1135523_2	1380600.AUYN01000001_gene2263	2.34e-100	295.0	COG2148@1|root,COG2148@2|Bacteria,4NNHR@976|Bacteroidetes,1I2JE@117743|Flavobacteriia	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k59_909743_1	1380600.AUYN01000010_gene842	7.13e-184	570.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1135532_1	323850.Shew_0003	1.13e-84	258.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,2Q9TF@267890|Shewanellaceae	1236|Gammaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_118998_1	313603.FB2170_07939	6.32e-61	189.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I6VR@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
k59_118998_2	1121875.KB907547_gene3144	2.53e-40	142.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1HY4Q@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1190816_1	85643.Tmz1t_3046	1.43e-128	377.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KUCB@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1361042_1	1380600.AUYN01000009_gene1565	3.12e-206	593.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,1HXJI@117743|Flavobacteriia	976|Bacteroidetes	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1757436_1	865937.Gilli_1714	3.26e-54	188.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2P76V@244698|Gillisia	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_458366_1	1123228.AUIH01000002_gene1437	6.48e-23	89.7	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XKFR@135619|Oceanospirillales	135619|Oceanospirillales	J	seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_458366_2	270374.MELB17_07219	1.41e-30	119.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,4642B@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1023140_1	1250006.JHZZ01000001_gene2231	2.42e-168	500.0	COG5434@1|root,COG5434@2|Bacteria,4PMGR@976|Bacteroidetes	976|Bacteroidetes	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_966412_1	749222.Nitsa_1009	8.54e-92	278.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_1305826_2	1319815.HMPREF0202_01955	2.36e-136	403.0	COG0402@1|root,COG0402@2|Bacteria,378PM@32066|Fusobacteria	32066|Fusobacteria	F	Psort location Cytoplasmic, score 9.97	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_1644444_1	317025.Tcr_0105	3.1e-08	60.1	COG4254@1|root,COG4254@2|Bacteria,1QUP0@1224|Proteobacteria,1T3X2@1236|Gammaproteobacteria,463UQ@72273|Thiotrichales	72273|Thiotrichales	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1530881_1	572480.Arnit_1934	5.78e-114	348.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_1248236_1	688270.Celal_1763	2.48e-62	208.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia,1F8Y2@104264|Cellulophaga	976|Bacteroidetes	P	COGs COG0038 Chloride channel protein EriC	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_1190847_1	1353528.DT23_13150	5.02e-15	73.2	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2XKH2@285107|Thioclava	28211|Alphaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1190847_2	1353528.DT23_13155	3.02e-95	284.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,2XM2H@285107|Thioclava	28211|Alphaproteobacteria	E	Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate	tyrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_1305853_1	710686.Mycsm_00611	3.38e-112	338.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,2354G@1762|Mycobacteriaceae	201174|Actinobacteria	E	gamma-glutamyltransferase	ggtA	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_1476194_1	1172190.M947_02760	1.75e-55	180.0	COG4106@1|root,COG4106@2|Bacteria,1QZ2S@1224|Proteobacteria,43CEU@68525|delta/epsilon subdivisions,2YTCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_1476194_2	929558.SMGD1_1212	2.18e-55	176.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1362627_1	653733.Selin_0067	5.32e-54	193.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K21088	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,dCache_2,dCache_3
k59_741941_1	313603.FB2170_07919	2.82e-120	357.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1HYK2@117743|Flavobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1476205_1	1000565.METUNv1_02250	1.89e-08	52.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,2VUEX@28216|Betaproteobacteria,2KWR4@206389|Rhodocyclales	206389|Rhodocyclales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_1476205_2	640081.Dsui_0371	1.23e-95	281.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2VKUA@28216|Betaproteobacteria,2KUIE@206389|Rhodocyclales	206389|Rhodocyclales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_703142_1	697303.Thewi_2210	7.28e-63	222.0	COG0643@1|root,COG0643@2|Bacteria,1V0ZX@1239|Firmicutes,24DDY@186801|Clostridia,42FCS@68295|Thermoanaerobacterales	186801|Clostridia	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1547777_1	1121931.AUHG01000010_gene125	2.19e-40	144.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_815593_1	1123037.AUDE01000001_gene1739	1.15e-90	275.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1HX7N@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_815593_2	1380600.AUYN01000007_gene3107	2.45e-140	409.0	28ICR@1|root,2Z8F0@2|Bacteria,4NHX1@976|Bacteroidetes,1I0RJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136002_1	929558.SMGD1_1512	2.92e-127	371.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1547783_1	929558.SMGD1_0288	2.04e-99	318.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1095825_1	694427.Palpr_2927	1.4e-69	221.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,2FWWQ@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
k59_1095825_2	269799.Gmet_1812	3.09e-38	145.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_306446_1	362418.IW19_10755	1.43e-77	259.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia,2NSVV@237|Flavobacterium	976|Bacteroidetes	KT	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
k59_419293_1	1116472.MGMO_83c00160	2.47e-59	199.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XESH@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_926760_1	572480.Arnit_1350	5.87e-109	338.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_80841_1	946077.W5A_07517	5.69e-266	739.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes,1HYBD@117743|Flavobacteriia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
k59_1606717_1	929558.SMGD1_2871	2.03e-63	208.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2YMTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_1492926_1	1380600.AUYN01000009_gene1931	0.0	941.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1492926_2	1380600.AUYN01000009_gene1930	1.13e-153	462.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
k59_361695_1	1565129.JSFF01000028_gene731	7.25e-101	306.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2QATE@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	iSDY_1059.SDY_1307	PLDc_2,PLDc_N
k59_870979_1	85643.Tmz1t_2437	1.75e-26	102.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,2KWGB@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_870979_2	1348657.M622_02415	1.81e-11	65.9	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,2KV38@206389|Rhodocyclales	206389|Rhodocyclales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_757316_1	411154.GFO_3449	2.09e-92	281.0	2C8CV@1|root,2Z8NV@2|Bacteria,4NH60@976|Bacteroidetes,1HZCW@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3095)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3095
k59_1492941_1	477228.YO5_06476	6.64e-66	217.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1Z3QJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_22661_1	1123518.ARWI01000001_gene366	6.63e-178	535.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T2N2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_9
k59_419342_1	1537917.JU82_08315	8.18e-111	328.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1662321_1	90814.KL370891_gene546	5.49e-56	192.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,460B9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1662321_2	1123518.ARWI01000001_gene771	1.03e-271	758.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,46056@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_532282_1	572480.Arnit_0422	1.96e-07	51.2	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP0921	Gp_dh_C,Gp_dh_N
k59_532282_2	572480.Arnit_0421	6.06e-112	323.0	COG1057@1|root,COG1057@2|Bacteria,1NG4J@1224|Proteobacteria,42P0F@68525|delta/epsilon subdivisions,2YMQR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,RsfS
k59_532282_3	572480.Arnit_0420	2.77e-05	44.3	COG0799@1|root,COG0799@2|Bacteria,1RCJN@1224|Proteobacteria,42TWB@68525|delta/epsilon subdivisions,2YPU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_193959_1	425104.Ssed_4114	7.84e-67	219.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RYVY@1236|Gammaproteobacteria,2Q9T1@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_193959_2	225849.swp_0429	1.84e-12	65.5	COG2009@1|root,31HUY@2|Bacteria,1RJJH@1224|Proteobacteria,1SZW0@1236|Gammaproteobacteria,2QERH@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM fumarate reductase respiratory complex, transmembrane subunit	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_136085_1	717774.Marme_3881	1.07e-37	132.0	COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,1RNP8@1236|Gammaproteobacteria,1XMQU@135619|Oceanospirillales	135619|Oceanospirillales	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
k59_136085_2	1206732.BAGD01000019_gene44	9.28e-05	46.2	COG1246@1|root,COG1246@2|Bacteria,2IP00@201174|Actinobacteria,4G1QY@85025|Nocardiaceae	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_703264_1	504487.JCM19302_2662	1.69e-62	215.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_871021_1	929558.SMGD1_1973	1.86e-94	288.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2YNA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_871021_2	1165841.SULAR_07108	2.64e-58	192.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_1324345_1	1406840.Q763_09770	9.28e-119	350.0	28HNW@1|root,2Z83K@2|Bacteria,4NJ3T@976|Bacteroidetes,1IIYN@117743|Flavobacteriia,2NU43@237|Flavobacterium	976|Bacteroidetes	S	Conjugal transfer protein TraM	-	-	-	-	-	-	-	-	-	-	-	-	Transposon_TraM
k59_80920_1	411154.GFO_1904	4.11e-88	278.0	COG2905@1|root,COG2905@2|Bacteria,4NDZ8@976|Bacteroidetes,1HWQU@117743|Flavobacteriia	976|Bacteroidetes	T	signal-transduction protein containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1606796_1	1353276.JADR01000006_gene1031	3.18e-84	270.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1606796_2	1380600.AUYN01000010_gene883	4.56e-122	359.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,1I0QJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,TPR_2,TPR_8
k59_1718737_1	1172190.M947_08600	1.45e-28	103.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2YQBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Redox-active disulfide protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_1718737_2	563040.Saut_0431	2.68e-68	215.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2YN61@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_815721_1	1565129.JSFF01000004_gene3125	5.56e-57	192.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,2QANM@267890|Shewanellaceae	1236|Gammaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
k59_1606806_1	1121931.AUHG01000019_gene3003	2.47e-104	313.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1718744_2	257310.BB2117	3e-18	82.8	2DBXD@1|root,2ZBP6@2|Bacteria,1RB44@1224|Proteobacteria,2VQT3@28216|Betaproteobacteria,3T6G7@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
k59_250725_1	616991.JPOO01000001_gene2784	3.59e-65	209.0	COG4225@1|root,COG4225@2|Bacteria,4NIET@976|Bacteroidetes,1I0HZ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861
k59_250725_2	616991.JPOO01000001_gene2785	2.19e-09	58.5	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,1HZCS@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
k59_1775826_1	517417.Cpar_2036	5.75e-05	45.8	COG0531@1|root,COG0531@2|Bacteria,1FESF@1090|Chlorobi	1090|Chlorobi	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_1775826_2	563040.Saut_1538	5.3e-27	100.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2YQ7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_1775826_3	929558.SMGD1_1917	2.4e-18	78.2	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,42W00@68525|delta/epsilon subdivisions,2YS8D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_306575_1	99598.Cal7507_6086	3.7e-12	64.7	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
k59_306575_2	1408473.JHXO01000007_gene758	8.46e-48	157.0	COG0546@1|root,COG0546@2|Bacteria,4NIJ1@976|Bacteroidetes,2G32Q@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_757405_1	1380600.AUYN01000009_gene1288	4.45e-125	363.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_757405_2	1121912.AUHD01000007_gene608	3.55e-38	138.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_1547934_1	425104.Ssed_2890	4.23e-104	318.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,2QA89@267890|Shewanellaceae	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_1493057_1	1448139.AI20_00070	3.27e-33	127.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,1Y5I3@135624|Aeromonadales	135624|Aeromonadales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_80984_1	411154.GFO_2808	2.32e-123	364.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1HZ60@117743|Flavobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_871095_1	765911.Thivi_1009	1.97e-09	60.1	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG3829@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3829@2|Bacteria,1NWAF@1224|Proteobacteria,1SRJQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	EAL,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_871095_2	1250006.JHZZ01000001_gene1791	2.08e-24	97.1	COG4565@1|root,COG4565@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,HTH_8,PAS_4,Response_reg,Sigma54_activat,SpoIIE
k59_871095_3	1178825.ALIH01000004_gene2884	4.3e-120	347.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1HZEU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_871095_4	216432.CA2559_06480	1.96e-18	84.3	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_419456_1	90813.JQMT01000001_gene1999	2.83e-37	131.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	mauD	-	-	ko:K12057	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AhpC-TSA,DUF4369,Thioredoxin,TraF
k59_419456_2	314345.SPV1_13092	5.98e-60	194.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria	1224|Proteobacteria	P	peroxidase	dyp	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
k59_361839_1	653733.Selin_0880	8.46e-72	235.0	COG1009@1|root,COG1009@2|Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00341,ko:K12137	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945	Proton_antipo_M,Proton_antipo_N
k59_979388_1	1537917.JU82_07120	2.56e-70	224.0	COG2897@1|root,COG2897@2|Bacteria,1PI99@1224|Proteobacteria,42PX2@68525|delta/epsilon subdivisions,2YNFU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_1435278_1	216432.CA2559_09823	6.62e-62	196.0	2E56Z@1|root,32ZZN@2|Bacteria,4NXCX@976|Bacteroidetes,1I5YS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_419473_1	1123514.KB905901_gene11	6.83e-94	285.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4605P@72273|Thiotrichales	72273|Thiotrichales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_705837_1	572480.Arnit_0750	3.01e-34	125.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_705837_2	572480.Arnit_0751	7.28e-95	278.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2YNVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1038	DHquinase_II
k59_24890_1	1123234.AUKI01000017_gene2483	6.75e-80	249.0	COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_196195_1	411154.GFO_3144	1.26e-86	258.0	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,1I2TS@117743|Flavobacteriia	976|Bacteroidetes	J	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_534518_1	563040.Saut_0906	9.55e-39	142.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_534518_2	326298.Suden_0859	3.06e-47	164.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2YMMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_929012_1	1137281.D778_01174	4.66e-160	459.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1HXUH@117743|Flavobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_1437382_1	1439940.BAY1663_04914	3.94e-80	255.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	transcriptional regulator	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_1778169_1	1236541.BALL01000047_gene4126	1.1e-109	326.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,2Q9BK@267890|Shewanellaceae	1236|Gammaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_196214_1	929558.SMGD1_1763	2.84e-104	313.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1042813_1	411154.GFO_0078	8.08e-45	147.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,1I2YA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_1042813_2	1249975.JQLP01000005_gene477	2.12e-17	83.6	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HXVC@117743|Flavobacteriia,2P61E@244698|Gillisia	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
k59_364030_1	1121931.AUHG01000016_gene1048	3.29e-64	205.0	COG1633@1|root,COG1633@2|Bacteria,4NHJB@976|Bacteroidetes,1HXQJ@117743|Flavobacteriia	976|Bacteroidetes	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
k59_929034_1	572480.Arnit_3058	4.06e-103	322.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43EDT@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	3.1.4.52	ko:K20964	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF3365,EAL,FIST,FIST_C,GGDEF,PAS_9,dCache_3
k59_1204959_1	1178825.ALIH01000001_gene2277	7.56e-157	451.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1HY2X@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_421621_1	504487.JCM19302_3774	3.76e-96	282.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1HYYB@117743|Flavobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k59_421621_2	641526.ADIWIN_1677	4.63e-118	341.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,1HWNV@117743|Flavobacteriia	976|Bacteroidetes	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
k59_421621_3	1178825.ALIH01000001_gene2339	2.64e-51	162.0	COG0011@1|root,COG0011@2|Bacteria,4NSNT@976|Bacteroidetes,1I3X9@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM Protein of	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_421621_4	641526.ADIWIN_1679	6.21e-36	128.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1HYFZ@117743|Flavobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
k59_308782_1	90814.KL370891_gene473	1.74e-166	479.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1T1IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	sfnR	-	-	ko:K06714,ko:K10943,ko:K11917	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022,ko02044,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_1495324_1	398720.MED217_15200	1.31e-111	328.0	2E3AK@1|root,2ZCCU@2|Bacteria,4NN6G@976|Bacteroidetes,1I1MB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1447489_2	748247.AZKH_4148	3.93e-22	95.5	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2VII5@28216|Betaproteobacteria,2KUUT@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_1278739_1	1565129.JSFF01000008_gene2679	2.82e-94	280.0	COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria,2QB08@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Methyladenine glycosylase	IV02_03670	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
k59_374394_1	563040.Saut_1099	3.71e-113	335.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2YMII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_374394_2	1249480.B649_06390	3.7e-16	77.8	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2YMII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_1391041_1	1828.JOKB01000054_gene1001	1.13e-08	56.6	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4FWE4@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_1391041_2	944547.ABLL_1835	2.91e-76	243.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2YMVZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
k59_148756_1	1156919.QWC_22449	1.19e-09	58.5	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,3T2Q9@506|Alcaligenaceae	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_148756_2	645991.Sgly_3196	1.02e-58	188.0	COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,24FU4@186801|Clostridia,261J4@186807|Peptococcaceae	186801|Clostridia	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
k59_1165535_1	1123517.JOMR01000001_gene81	6.06e-91	293.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,461TY@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase HrpB	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_1051900_1	1172190.M947_01775	2.61e-50	163.0	2AJ4J@1|root,319P3@2|Bacteria,1Q3DP@1224|Proteobacteria,42X5G@68525|delta/epsilon subdivisions,2YQYN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1051900_2	326298.Suden_0536	4.42e-41	150.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1447503_1	572480.Arnit_2670	2.49e-72	237.0	COG0699@1|root,COG0699@2|Bacteria,1NBKR@1224|Proteobacteria,42NDN@68525|delta/epsilon subdivisions,2YN3H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_1337497_1	143224.JQMD01000002_gene1433	8.71e-98	302.0	COG5653@1|root,COG5653@2|Bacteria,4NHPG@976|Bacteroidetes,1HY5R@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_1337497_2	1046627.BZARG_117	6.42e-74	244.0	COG5653@1|root,COG5653@2|Bacteria,4NHPG@976|Bacteroidetes,1HY5R@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_1337497_3	1121012.AUKX01000018_gene1621	5.33e-59	203.0	COG5653@1|root,COG5653@2|Bacteria,4NPQD@976|Bacteroidetes,1I251@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_1391049_1	1122225.AULQ01000006_gene1031	1.26e-98	302.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1HZGJ@117743|Flavobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_148770_1	1197477.IA57_03270	4.43e-138	417.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_319383_1	1396141.BATP01000003_gene5214	2.69e-33	131.0	COG3291@1|root,COG4124@1|root,COG5492@1|root,COG3291@2|Bacteria,COG4124@2|Bacteria,COG5492@2|Bacteria,46UXF@74201|Verrucomicrobia,2IV2T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GN	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
k59_1619779_1	1380600.AUYN01000009_gene1371	1.05e-67	207.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
k59_1619779_2	1380600.AUYN01000009_gene1370	6.48e-26	103.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1HWR8@117743|Flavobacteriia	976|Bacteroidetes	E	fad dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1278791_1	1178825.ALIH01000003_gene2187	4.46e-108	324.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1674978_1	323848.Nmul_A2725	3.56e-33	130.0	COG2199@1|root,COG5002@1|root,COG2199@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2W0JH@28216|Betaproteobacteria	28216|Betaproteobacteria	T	sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_9
k59_717194_1	1165841.SULAR_04678	1.26e-113	338.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1391098_1	1537915.JU57_02420	1.29e-134	384.0	2E7J7@1|root,3321G@2|Bacteria,1NCI7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1506174_1	317025.Tcr_0529	2e-16	86.3	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,45ZMZ@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_206549_2	679926.Mpet_0686	3.7e-20	86.3	COG0239@1|root,arCOG04701@2157|Archaea,2XY0N@28890|Euryarchaeota,2NB1Z@224756|Methanomicrobia	224756|Methanomicrobia	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	-	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_991768_1	411154.GFO_0709	1.47e-84	253.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,1HYIR@117743|Flavobacteriia	976|Bacteroidetes	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_488924_1	317025.Tcr_0427	2.32e-171	487.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_488924_2	1168067.JAGP01000001_gene1854	5.68e-76	227.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S3XZ@1236|Gammaproteobacteria,460VK@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
k59_488924_3	317025.Tcr_0429	4.38e-53	173.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,45ZUF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_1337566_1	316067.Geob_1092	2.27e-82	249.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_1165610_2	211586.SO_4270	6.57e-59	194.0	2EJKM@1|root,33DBI@2|Bacteria,1NZ6U@1224|Proteobacteria,1SQH9@1236|Gammaproteobacteria,2QD67@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_717222_2	907239.HPSA_07265	1.8e-33	129.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42Q2X@68525|delta/epsilon subdivisions,2YMSI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2189 adenine specific DNA methylase Mod	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_34851_1	1328313.DS2_02298	2.69e-49	168.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nrtC	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_34851_2	1121931.AUHG01000017_gene1483	1.66e-69	226.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1447603_1	1168289.AJKI01000011_gene443	7.6e-14	76.6	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,2FXT6@200643|Bacteroidia,3XJ4P@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_2,Reg_prop,SpoIIE,Y_Y_Y
k59_1337593_1	406124.ACPC01000020_gene3943	1.01e-31	122.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,4IRPK@91061|Bacilli,1ZRWE@1386|Bacillus	91061|Bacilli	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
k59_432177_1	929558.SMGD1_2159	3.91e-25	110.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,TPR_8,VWA_2
k59_770039_1	929558.SMGD1_2308	1.85e-48	166.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_770039_3	1172190.M947_11250	1.08e-13	68.9	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42TAC@68525|delta/epsilon subdivisions,2YRI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG2518 Protein-L-isoaspartate carboxylmethyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_883739_1	926559.JoomaDRAFT_2870	7.92e-49	176.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1506228_1	1128912.GMES_3516	2.48e-49	169.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,1RR6N@1236|Gammaproteobacteria,4660U@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1506228_2	1026882.MAMP_00571	1.32e-35	137.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,1RY4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	outer membrane autotransporter barrel domain	-	-	-	ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Autotransporter,PAP2,PATR,Peptidase_S8
k59_1619843_1	572480.Arnit_2994	5.91e-143	416.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2YTA6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_319479_1	1178825.ALIH01000009_gene1287	1.46e-53	176.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_319479_2	504487.JCM19302_4119	1e-48	162.0	COG2825@1|root,COG2825@2|Bacteria,4NN8F@976|Bacteroidetes,1I21G@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_1447623_1	411154.GFO_1453	1.29e-54	172.0	COG4818@1|root,COG4818@2|Bacteria,4NUVP@976|Bacteroidetes,1I44F@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1447623_2	1121931.AUHG01000012_gene2713	1.42e-05	45.8	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia	976|Bacteroidetes	S	Phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_717267_1	1565129.JSFF01000002_gene3567	1.98e-142	412.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,2Q9MC@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_374528_1	317025.Tcr_0851	2.12e-65	203.0	COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,1RXZV@1236|Gammaproteobacteria,461UE@72273|Thiotrichales	72273|Thiotrichales	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_374528_2	317025.Tcr_0850	1.01e-72	223.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,460I5@72273|Thiotrichales	72273|Thiotrichales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_1506243_1	572480.Arnit_1658	1.32e-181	531.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_658523_1	926559.JoomaDRAFT_0206	3.14e-52	185.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1731445_1	1042375.AFPL01000010_gene449	2.72e-12	62.4	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,467XS@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the urease beta subunit family	ureB	GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_1322,iECO103_1326.ECO103_3798,iECO111_1330.ECO111_1228,iECSP_1301.ECSP_1250,iECs_1301.ECs1323,iUMNK88_1353.UMNK88_1200,iZ_1308.Z1144,iZ_1308.Z1583	Urease_beta
k59_1731445_2	1298593.TOL_0967	4.21e-94	290.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,1XHPP@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_432237_1	1380600.AUYN01000009_gene1924	1.77e-41	139.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_432237_3	1178825.ALIH01000002_gene859	1.69e-130	374.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k59_1560589_1	637905.SVI_4233	1.25e-77	242.0	COG0786@1|root,COG0786@2|Bacteria,1MVBC@1224|Proteobacteria,1RP0S@1236|Gammaproteobacteria,2Q9YE@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Catalyzes the sodium-dependent transport of glutamate	gltS	GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015501,GO:0015672,GO:0015711,GO:0015849,GO:0016020,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	iPC815.YPO0035,iZ_1308.Z5081	Glt_symporter
k59_1677877_1	305700.B447_06387	3.67e-57	207.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KZQA@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1168435_1	1123518.ARWI01000001_gene2190	1.47e-125	380.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,45ZNZ@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1168435_2	90814.KL370891_gene1467	4.56e-59	190.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,45ZU8@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1394088_1	563040.Saut_1359	1.19e-31	116.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2YNTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_1394088_2	563040.Saut_1353	2.88e-169	499.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_546245_3	521097.Coch_0900	2.48e-20	89.0	2C091@1|root,32UF3@2|Bacteria,4NSYS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_886608_1	317025.Tcr_1145	8.09e-107	325.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,45ZPV@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_322357_1	1408473.JHXO01000013_gene629	6.21e-39	136.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,2FNPU@200643|Bacteroidia	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_322357_2	714943.Mucpa_1184	2.86e-19	86.3	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1509178_1	1178825.ALIH01000001_gene2641	2.12e-133	392.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_1509178_2	1380600.AUYN01000009_gene1750	1.17e-132	377.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_1054321_1	1121931.AUHG01000010_gene719	3.53e-63	211.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_1054321_2	1121931.AUHG01000010_gene718	8.67e-91	277.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia	976|Bacteroidetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_602393_1	572480.Arnit_1933	3.88e-126	373.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_1450558_1	1123514.KB905899_gene450	8.51e-40	137.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,460HZ@72273|Thiotrichales	72273|Thiotrichales	O	Stringent starvation protein A	-	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N_3
k59_1450558_2	317025.Tcr_1738	5.25e-63	196.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,4610Q@72273|Thiotrichales	72273|Thiotrichales	S	Stringent starvation protein B	-	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
k59_940568_1	90813.JQMT01000001_gene1392	1.93e-49	177.0	COG5001@1|root,COG5001@2|Bacteria,1R59J@1224|Proteobacteria,1SMVJ@1236|Gammaproteobacteria,461V3@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1734227_1	87626.PTD2_07629	1.08e-16	80.1	COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria,2Q2IN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
k59_1734227_2	402612.FP1376	1.61e-19	86.3	COG1216@1|root,COG1216@2|Bacteria,4NJ4N@976|Bacteroidetes,1HYD8@117743|Flavobacteriia,2NUMA@237|Flavobacterium	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1111683_2	937777.Deipe_1644	2.42e-14	69.3	2EHP8@1|root,33BF1@2|Bacteria	2|Bacteria	S	Multiubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	Multi_ubiq
k59_1394148_1	945713.IALB_2371	8.5e-84	265.0	COG0481@1|root,COG0481@2|Bacteria	2|Bacteria	M	GTPase activity	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_772849_1	326298.Suden_1134	1.01e-201	565.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_772849_2	1232437.KL662001_gene4624	5.61e-06	48.1	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MHKH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_491689_1	675817.VDA_001695	2.13e-94	288.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1XV6P@135623|Vibrionales	135623|Vibrionales	G	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific	ptsG	-	2.7.1.199	ko:K02778,ko:K02779	ko00010,ko00520,ko02060,ko05111,map00010,map00520,map02060,map05111	M00265	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1	-	-	PTS_EIIB,PTS_EIIC
k59_501957_1	929558.SMGD1_0542	2.38e-106	331.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_107181_1	945713.IALB_1615	3.48e-132	384.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_219868_1	1208321.D104_13460	5.45e-100	302.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria,1XIQ9@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_1350968_1	563040.Saut_1942	5.54e-116	333.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2YN1Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_1350970_2	1123228.AUIH01000004_gene1141	1.19e-66	221.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XHYK@135619|Oceanospirillales	135619|Oceanospirillales	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_161207_1	1565129.JSFF01000031_gene2961	6.51e-116	352.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,1RRGG@1236|Gammaproteobacteria,2Q98C@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
k59_387785_1	1565129.JSFF01000025_gene1298	2.77e-197	555.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RNSR@1236|Gammaproteobacteria,2Q8PI@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the conversion of chorismate to isochorismate	menF	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008909,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009233,GO:0009234,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042180,GO:0042181,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046872,GO:0050486,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901661,GO:1901663,GO:1902494	5.4.4.2	ko:K01851,ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c26010,iECIAI39_1322.ECIAI39_2413,iSF_1195.SF2344,iS_1188.S2478,ic_1306.c2809	Chorismate_bind
k59_1459980_1	1197477.IA57_08280	3.49e-89	267.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1HXDV@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_1459980_2	745718.JADT01000008_gene3127	4.73e-59	182.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_1459980_4	1121912.AUHD01000007_gene586	8.43e-155	436.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1HXI0@117743|Flavobacteriia	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_895895_1	1122983.BAJY01000003_gene1924	1.67e-60	201.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,2FP4W@200643|Bacteroidia	976|Bacteroidetes	D	SpoIID LytB domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
k59_1802119_1	1121931.AUHG01000011_gene2322	2.21e-49	162.0	COG3011@1|root,COG3011@2|Bacteria,4NPGN@976|Bacteroidetes,1I2KY@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
k59_1745280_2	1123518.ARWI01000001_gene929	4.17e-122	353.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,45ZVH@72273|Thiotrichales	72273|Thiotrichales	H	PFAM MoeZ MoeB domain	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_1122427_1	929558.SMGD1_2622	6.13e-67	214.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_1122427_2	1537917.JU82_05870	9.38e-40	134.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2YPC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k59_219939_1	1121931.AUHG01000011_gene2323	2.07e-127	369.0	COG1609@1|root,COG1609@2|Bacteria,4NJDR@976|Bacteroidetes,1I07H@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k59_47115_1	411154.GFO_2241	8.41e-169	475.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_1351089_1	1178825.ALIH01000007_gene1615	6.8e-137	412.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1224668_1	1123518.ARWI01000001_gene288	1.05e-77	234.0	COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,1SA1H@1236|Gammaproteobacteria,4623Y@72273|Thiotrichales	72273|Thiotrichales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_1224668_2	935866.JAER01000009_gene716	1.29e-16	73.2	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DS16@85009|Propionibacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_1224678_1	563040.Saut_0556	1.52e-115	346.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YR82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1292175_3	1122225.AULQ01000009_gene341	6.64e-112	371.0	2EAST@1|root,334US@2|Bacteria,4NRGD@976|Bacteroidetes,1I583@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_387918_2	326298.Suden_1339	3.43e-80	243.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2YN03@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1573126_1	1453505.JASY01000007_gene1175	6.21e-90	291.0	COG3513@1|root,COG3513@2|Bacteria,4NFM9@976|Bacteroidetes,1HYZN@117743|Flavobacteriia,2NTXY@237|Flavobacterium	976|Bacteroidetes	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_4
k59_1064765_1	1286093.C266_24328	7.7e-52	173.0	COG0625@1|root,COG0625@2|Bacteria,1NUET@1224|Proteobacteria,2VKA7@28216|Betaproteobacteria,1K4M5@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gstN	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
k59_502114_1	1380600.AUYN01000006_gene696	3.95e-169	477.0	COG3677@1|root,COG3677@2|Bacteria,4NJC5@976|Bacteroidetes,1I0Y5@117743|Flavobacteriia	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_1224706_1	572480.Arnit_2302	5.64e-77	237.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_220011_2	867900.Celly_2612	5.82e-41	154.0	COG0110@1|root,COG1086@1|root,COG2348@1|root,COG0110@2|Bacteria,COG1086@2|Bacteria,COG2348@2|Bacteria,4NJG8@976|Bacteroidetes,1HYQK@117743|Flavobacteriia,1F8F2@104264|Cellulophaga	976|Bacteroidetes	GMV	TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB,FemAB_like
k59_784087_1	215803.DB30_0409	1.13e-16	85.9	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
k59_220013_2	945713.IALB_3206	2.18e-20	81.6	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k59_107353_1	485917.Phep_3700	1.39e-58	182.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1ISFJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
k59_107353_2	1353276.JADR01000014_gene2989	1.01e-22	95.1	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1I52E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_784095_1	563040.Saut_0132	1.49e-13	77.4	COG2604@1|root,COG2604@2|Bacteria,1Q4PY@1224|Proteobacteria,42X2A@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1460132_1	90814.KL370891_gene1672	6.84e-122	354.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,460E8@72273|Thiotrichales	72273|Thiotrichales	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_1460132_2	1123518.ARWI01000001_gene1981	1.46e-51	171.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,460AY@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1292212_1	563040.Saut_0887	6.14e-74	232.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42YMW@68525|delta/epsilon subdivisions,2YP3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_1292212_2	326298.Suden_1341	1.3e-32	120.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_505137_2	349521.HCH_04707	2.69e-41	135.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XKKE@135619|Oceanospirillales	135619|Oceanospirillales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_505137_3	326442.PSHAa0109	1.02e-22	96.7	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,2Q0NE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG0513 Superfamily II DNA and RNA helicases	dbpA	GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_447819_1	458817.Shal_3616	1.39e-68	208.0	COG0848@1|root,COG0848@2|Bacteria,1QI7X@1224|Proteobacteria,1TG1Y@1236|Gammaproteobacteria,2QDF9@267890|Shewanellaceae	1236|Gammaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_447819_2	458817.Shal_3617	4.52e-32	115.0	COG0811@1|root,COG0811@2|Bacteria,1QBZT@1224|Proteobacteria,1T7M3@1236|Gammaproteobacteria,2QD7N@267890|Shewanellaceae	1236|Gammaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1008377_1	1355368.JART01000025_gene59	1.13e-15	75.1	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2YMEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
k59_1008377_2	983545.Glaag_1256	8.41e-27	107.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,464GG@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1083 CMP-N-acetylneuraminic acid synthetase	neuA	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Lipase_GDSL_2
k59_1575936_1	572480.Arnit_2782	5.01e-169	472.0	COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria	1224|Proteobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
k59_1575936_2	572480.Arnit_2781	1.3e-06	46.6	2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria	1224|Proteobacteria	S	pyrroloquinoline quinone biosynthesis protein D	pqqD	-	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
k59_899105_1	1355368.JART01000007_gene1368	7.48e-24	91.7	COG0255@1|root,COG0255@2|Bacteria,1Q5ZI@1224|Proteobacteria,42VCR@68525|delta/epsilon subdivisions,2YQ6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_899105_2	572480.Arnit_1112	9.69e-53	166.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2YPV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_899105_3	944547.ABLL_0984	6.88e-34	118.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2YP6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_675289_1	1178825.ALIH01000016_gene601	2.22e-107	321.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1295416_1	929558.SMGD1_1291	4.51e-55	181.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2YMFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1295416_2	563040.Saut_0044	2.27e-141	407.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_787261_1	1121931.AUHG01000011_gene1625	4.97e-184	518.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,1HXP5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_899148_1	946077.W5A_04089	2.19e-88	281.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_675312_1	985255.APHJ01000023_gene2663	3.05e-25	102.0	COG0845@1|root,COG0845@2|Bacteria,4NMQS@976|Bacteroidetes,1I1M7@117743|Flavobacteriia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_675312_2	1353276.JADR01000008_gene888	0.0	1013.0	COG0841@1|root,COG0841@2|Bacteria,4NGVM@976|Bacteroidetes,1HYZV@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1523144_1	1188252.AJYK01000070_gene2153	2.69e-125	367.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XVS8@135623|Vibrionales	135623|Vibrionales	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_110520_1	411154.GFO_3007	3.6e-121	357.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1HYGI@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_734004_1	323850.Shew_3174	6.98e-72	224.0	COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,2QABK@267890|Shewanellaceae	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21699	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_734004_2	1565129.JSFF01000002_gene3406	2.97e-16	76.3	COG0583@1|root,COG0583@2|Bacteria,1QYAP@1224|Proteobacteria,1RYE8@1236|Gammaproteobacteria,2QABK@267890|Shewanellaceae	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21699	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_734008_1	398720.MED217_00040	4.03e-100	299.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HWM7@117743|Flavobacteriia,2XIWN@283735|Leeuwenhoekiella	976|Bacteroidetes	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1125613_2	1408442.JADE01000005_gene1210	1.35e-28	111.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,43BNE@68525|delta/epsilon subdivisions,2YMGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
k59_222919_1	1088721.NSU_0950	6.05e-32	116.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,2K3Z0@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_222919_2	517722.AEUE01000003_gene1549	1.36e-27	103.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria,2K4G3@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_675348_1	1443665.JACA01000020_gene5009	9.66e-59	192.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1HYEP@117743|Flavobacteriia,2YICJ@290174|Aquimarina	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
k59_675348_2	1380600.AUYN01000001_gene2499	2.31e-48	161.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_505230_1	1123518.ARWI01000001_gene1067	9.69e-123	363.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,460C8@72273|Thiotrichales	72273|Thiotrichales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_505230_2	1168067.JAGP01000001_gene224	3.65e-124	355.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,4605S@72273|Thiotrichales	72273|Thiotrichales	EH	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_505230_3	1123517.JOMR01000001_gene1901	1.08e-28	112.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,460C1@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_899202_1	272123.Anacy_4636	3.19e-15	80.5	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1GQPF@1117|Cyanobacteria,1HSSH@1161|Nostocales	1117|Cyanobacteria	O	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VCBS
k59_1295497_1	929558.SMGD1_0835	2.99e-202	572.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2YMQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_164661_1	1353276.JADR01000003_gene2754	6.39e-128	393.0	COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,4PKRK@976|Bacteroidetes,1IJDQ@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_952019_1	929703.KE386491_gene1162	2.25e-05	47.8	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47MAI@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_899233_1	305900.GV64_02125	8.26e-79	255.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales	135619|Oceanospirillales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_222970_1	1121931.AUHG01000012_gene2711	2.77e-106	317.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1405933_2	323850.Shew_1448	4.95e-39	130.0	2EN8F@1|root,33FW8@2|Bacteria,1NGRJ@1224|Proteobacteria,1SJ12@1236|Gammaproteobacteria,2QCPT@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	SO3132	-	-	-	-	-	-	-	-	-	-	-	-
k59_110592_2	90814.KL370891_gene1718	1.82e-28	114.0	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,1SFE3@1236|Gammaproteobacteria,461HT@72273|Thiotrichales	72273|Thiotrichales	NU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_677952_2	1123228.AUIH01000012_gene27	3.02e-46	153.0	COG0454@1|root,COG0456@2|Bacteria,1MZQ5@1224|Proteobacteria,1S45R@1236|Gammaproteobacteria,1XMKB@135619|Oceanospirillales	135619|Oceanospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
k59_1016880_1	945713.IALB_0562	1.92e-40	152.0	COG0642@1|root,COG0745@1|root,COG2199@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheX,HAMP,HATPase_c,HisKA,Response_reg
k59_1129872_1	292414.TM1040_2780	2.05e-10	63.2	COG1522@1|root,COG1522@2|Bacteria,1RB79@1224|Proteobacteria,2VG6T@28211|Alphaproteobacteria,4NDQH@97050|Ruegeria	28211|Alphaproteobacteria	K	IclR helix-turn-helix domain	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_960376_1	1185876.BN8_01406	8.94e-112	359.0	COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,47KA9@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
k59_113116_1	411154.GFO_0009	2.1e-23	99.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,1HYGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	DUF4980,Glyco_hydro_32C,Glyco_hydro_32N
k59_113116_2	411154.GFO_0012	1.3e-91	275.0	COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,1HYZ6@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_508476_1	1123518.ARWI01000001_gene137	3.79e-113	332.0	COG0835@1|root,COG3437@1|root,COG0835@2|Bacteria,COG3437@2|Bacteria,1RD7I@1224|Proteobacteria,1SKFD@1236|Gammaproteobacteria,46261@72273|Thiotrichales	72273|Thiotrichales	T	Two component signalling adaptor domain	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1581748_1	1123514.KB905903_gene378	7.39e-32	121.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,46070@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1581748_2	1123368.AUIS01000013_gene837	1.72e-57	192.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,2NC8A@225057|Acidithiobacillales	2|Bacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_903920_1	1134474.O59_002845	2.02e-64	215.0	COG2730@1|root,COG2730@2|Bacteria,1N21U@1224|Proteobacteria,1RRB0@1236|Gammaproteobacteria,1FI7D@10|Cellvibrio	1236|Gammaproteobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Cellulase
k59_621492_1	313603.FB2170_07964	2.32e-59	184.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1IJ1X@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_621492_2	313603.FB2170_07959	1.16e-103	301.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_960401_1	62928.azo2537	4.38e-91	272.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria,2KY5W@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
k59_960401_2	497321.C664_11505	5.87e-09	55.8	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2VIRJ@28216|Betaproteobacteria,2KYJV@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
k59_1751216_1	1178825.ALIH01000003_gene2234	1.31e-05	46.2	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_1751216_2	313595.P700755_001230	1.5e-35	136.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1HXCC@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_395562_1	998088.B565_0425	2.09e-06	52.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1Y4CE@135624|Aeromonadales	135624|Aeromonadales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1299328_1	1484460.JSWG01000015_gene1026	6.88e-118	394.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG3420@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
k59_452036_1	1353276.JADR01000001_gene712	2.78e-73	228.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HWM7@117743|Flavobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_452036_2	746697.Aeqsu_0637	2.13e-21	86.3	2E4IE@1|root,32ZDH@2|Bacteria,4NUR6@976|Bacteroidetes,1I59Y@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
k59_452036_3	1353276.JADR01000001_gene710	2.66e-43	156.0	COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1HY7J@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_847388_1	1565129.JSFF01000005_gene2298	6.66e-112	334.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,2Q9C6@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
k59_169656_1	1178825.ALIH01000004_gene2977	4.45e-102	306.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_113154_1	85643.Tmz1t_0521	3.54e-80	245.0	COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,2VQQM@28216|Betaproteobacteria,2KWK3@206389|Rhodocyclales	206389|Rhodocyclales	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
k59_339041_1	1380600.AUYN01000009_gene1911	1.97e-82	273.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1073384_2	411154.GFO_1829	6.3e-79	242.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1I0IS@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1638278_1	1250006.JHZZ01000001_gene2221	4.81e-17	80.5	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IC3K@117743|Flavobacteriia,3VXCE@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1638278_2	1178825.ALIH01000007_gene1640	8.31e-10	57.8	2E3VR@1|root,32YSX@2|Bacteria,4NURS@976|Bacteroidetes,1I5DT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1638278_3	1168034.FH5T_01920	2.89e-249	714.0	COG3408@1|root,COG3408@2|Bacteria,4NFHH@976|Bacteroidetes,2FQTQ@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
k59_1242845_1	929558.SMGD1_2520	7.08e-45	157.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1242845_2	1278309.KB907101_gene703	7.88e-22	88.6	COG5460@1|root,COG5460@2|Bacteria,1N7MS@1224|Proteobacteria,1SCTR@1236|Gammaproteobacteria,1XM7X@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
k59_1242845_3	929558.SMGD1_2519	1.04e-08	55.5	COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2YNGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_339048_1	1123514.KB905899_gene1694	3.71e-06	50.1	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,46095@72273|Thiotrichales	72273|Thiotrichales	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_339048_2	317025.Tcr_0406	6.62e-111	324.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S953@1236|Gammaproteobacteria,4611G@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
k59_339048_3	1123518.ARWI01000001_gene902	2.92e-87	264.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,4605Y@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_169673_1	90814.KL370891_gene235	4.42e-52	169.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,460DP@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_169673_2	1123518.ARWI01000001_gene1036	4.4e-51	162.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,4616H@72273|Thiotrichales	72273|Thiotrichales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_169673_3	1123518.ARWI01000001_gene1035	4.95e-182	508.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,45ZZI@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_169673_4	1123518.ARWI01000001_gene1034	2.27e-59	183.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,460UJ@72273|Thiotrichales	72273|Thiotrichales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_170116_3	1168067.JAGP01000001_gene1927	1.32e-108	327.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4603T@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_1017400_1	1123517.JOMR01000001_gene1020	3.23e-24	94.7	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SH2C@1236|Gammaproteobacteria,461FB@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1017400_2	1123514.KB905899_gene947	1.72e-60	202.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,45ZWA@72273|Thiotrichales	72273|Thiotrichales	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1412812_1	929558.SMGD1_2720	1.12e-99	303.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_1130405_1	1123518.ARWI01000001_gene1874	1.93e-24	96.3	2CJXA@1|root,34B9A@2|Bacteria,1P02H@1224|Proteobacteria,1SSIG@1236|Gammaproteobacteria,462XV@72273|Thiotrichales	72273|Thiotrichales	S	FliG C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FliG_C
k59_1130405_2	90814.KL370891_gene1772	3.91e-129	379.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,45ZRP@72273|Thiotrichales	72273|Thiotrichales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_1638747_1	323850.Shew_0225	8.08e-121	346.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,2Q92B@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271,ko:K12961	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
k59_1638747_2	323850.Shew_0224	7.98e-64	199.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,2Q9IV@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SMART Transport-associated and nodulation region	yraP	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	BON
k59_1412817_1	317025.Tcr_1777	5.32e-28	113.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K12340,ko:K12538	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00328,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,1.B.17.1,2.A.6.2	-	-	OEP
k59_1412817_2	317025.Tcr_1778	2.16e-75	251.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,45ZY9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_622011_2	1123326.JFBL01000009_gene885	6.52e-36	130.0	COG2207@1|root,COG2207@2|Bacteria,1R6WN@1224|Proteobacteria,42SYR@68525|delta/epsilon subdivisions,2YPHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1243206_1	700598.Niako_1079	3.88e-47	172.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,4NHK1@976|Bacteroidetes,1J0FS@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
k59_702_1	572480.Arnit_0793	1.3e-43	149.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_702_2	572480.Arnit_0792	7.23e-28	107.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,42UMA@68525|delta/epsilon subdivisions,2YQ5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_709_1	1121931.AUHG01000010_gene810	6.19e-07	48.5	COG2197@1|root,COG2197@2|Bacteria,4PKIY@976|Bacteroidetes,1I9YT@117743|Flavobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_709_2	411154.GFO_0149	1.58e-156	462.0	COG2202@1|root,COG3452@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3452@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,PAS_3,PAS_9
k59_452517_1	1123514.KB905899_gene1154	7.86e-38	141.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,460CG@72273|Thiotrichales	72273|Thiotrichales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k59_452517_2	90814.KL370891_gene1327	1.19e-51	167.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,460Z7@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Uncharacterised P-loop hydrolase UPF0079	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_113663_1	1380600.AUYN01000009_gene1006	9.29e-102	301.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1HY0R@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_113663_2	1178825.ALIH01000007_gene1617	5.26e-126	362.0	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,1I060@117743|Flavobacteriia	976|Bacteroidetes	M	Inorganic polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_113663_3	1380600.AUYN01000009_gene1004	7.91e-146	414.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_113663_4	1380600.AUYN01000009_gene1003	4.05e-132	402.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1695220_1	983544.Lacal_1853	3.41e-190	538.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1HWUA@117743|Flavobacteriia	976|Bacteroidetes	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1243225_1	573569.F7308_0863	1.63e-79	242.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,1S2EG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_1243225_2	525898.Sdel_2224	2.3e-21	91.3	COG0535@1|root,COG0535@2|Bacteria,1PEYS@1224|Proteobacteria,42SNS@68525|delta/epsilon subdivisions,2YQGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_113682_1	1121931.AUHG01000011_gene1854	2.69e-42	139.0	COG0607@1|root,COG0607@2|Bacteria,4NTEZ@976|Bacteroidetes,1I4AC@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_113682_2	1121931.AUHG01000011_gene1855	1.56e-99	293.0	2DKYU@1|root,30Y2N@2|Bacteria,4NPDW@976|Bacteroidetes,1I2J5@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1299887_1	983544.Lacal_1740	4.9e-51	168.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
k59_565542_1	1121931.AUHG01000011_gene1667	2.67e-133	389.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,1HYHT@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_170186_1	1123518.ARWI01000001_gene343	4.15e-38	139.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4606C@72273|Thiotrichales	72273|Thiotrichales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
k59_170186_2	90814.KL370891_gene953	5.97e-157	450.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,45ZQU@72273|Thiotrichales	72273|Thiotrichales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1186921_1	1051646.VITU9109_17193	1.68e-112	350.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,1RNKC@1236|Gammaproteobacteria,1Y30Y@135623|Vibrionales	135623|Vibrionales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1582274_2	317025.Tcr_1990	4.85e-19	86.3	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,460MG@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k59_396136_1	935863.AWZR01000005_gene2280	1.48e-81	252.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1X3FN@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_1525768_1	1121904.ARBP01000009_gene4353	2.34e-40	136.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,47RGC@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
k59_1525768_2	1121931.AUHG01000016_gene1123	1.76e-23	94.0	2BZIG@1|root,32RZU@2|Bacteria,4NU2S@976|Bacteroidetes,1I4HS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_508883_2	90814.KL370891_gene1050	1.57e-33	122.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,460UW@72273|Thiotrichales	72273|Thiotrichales	IQ	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_960915_1	1565129.JSFF01000008_gene2704	4.87e-123	373.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,2Q924@267890|Shewanellaceae	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_113716_1	1137281.D778_02496	5.17e-98	300.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfate permease	ychM	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_565567_1	1123517.JOMR01000001_gene922	3.72e-26	105.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,45ZTU@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_565567_2	90814.KL370891_gene1295	8.1e-38	139.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1412915_1	317025.Tcr_0460	2.61e-47	155.0	COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,1SFP7@1236|Gammaproteobacteria,4618E@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
k59_1412915_2	1123518.ARWI01000001_gene1911	8.04e-28	101.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SF0T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1412915_3	1123514.KB905899_gene840	3.7e-42	142.0	2A49J@1|root,30SV1@2|Bacteria,1RF7U@1224|Proteobacteria,1S3TV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1017508_1	326298.Suden_0353	2.21e-77	256.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1017508_2	1172190.M947_07035	8.82e-41	148.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1751794_1	1353528.DT23_09420	6.42e-99	300.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,2TUF4@28211|Alphaproteobacteria,2XM3P@285107|Thioclava	28211|Alphaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	noeK	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_113753_1	323850.Shew_2837	3.26e-34	120.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,2QBKY@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_1243276_1	411154.GFO_1440	4e-86	253.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_1243276_2	411154.GFO_1441	2.04e-60	192.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia	976|Bacteroidetes	EH	Aminotransferase class IV	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1130551_1	1121931.AUHG01000011_gene2235	1.33e-132	397.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_1017538_1	326298.Suden_1138	9.95e-77	237.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2YMCF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_1017538_2	326298.Suden_1137	1.88e-29	105.0	2AK1D@1|root,31AQZ@2|Bacteria,1Q5ZH@1224|Proteobacteria,42V6N@68525|delta/epsilon subdivisions,2YQ6B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_678626_1	90813.JQMT01000001_gene973	1.68e-29	106.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,460YP@72273|Thiotrichales	72273|Thiotrichales	S	PFAM YCII-related	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k59_678626_2	1565129.JSFF01000011_gene1937	1.3e-91	273.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,2Q8VR@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM Endonuclease exonuclease phosphatase	xthA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_1017545_1	1168067.JAGP01000001_gene588	1.93e-55	182.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,460DZ@72273|Thiotrichales	72273|Thiotrichales	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1525832_1	411154.GFO_0182	2.06e-168	524.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_57322_1	411154.GFO_0576	1.87e-92	289.0	COG1216@1|root,COG1216@2|Bacteria,4NI78@976|Bacteroidetes,1HXTP@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1356264_1	1380600.AUYN01000009_gene1365	2.2e-194	545.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_1356264_2	1380600.AUYN01000009_gene1366	1.89e-133	389.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_904598_1	1123228.AUIH01000009_gene1920	2.32e-93	286.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1XHHE@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
k59_226785_1	425104.Ssed_3204	2.16e-107	344.0	COG0304@1|root,COG0764@1|root,COG3321@1|root,COG0304@2|Bacteria,COG0764@2|Bacteria,COG3321@2|Bacteria,1MU1X@1224|Proteobacteria,1RQAQ@1236|Gammaproteobacteria,2Q8ZW@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
k59_1187038_1	929558.SMGD1_0305	7.43e-101	301.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2YMQ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_1638936_1	1392489.JPOL01000002_gene2788	2.59e-112	337.0	COG0477@1|root,COG0477@2|Bacteria,4PKB1@976|Bacteroidetes,1HX4H@117743|Flavobacteriia,2XJQD@283735|Leeuwenhoekiella	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_1469229_1	1484460.JSWG01000006_gene2961	6.63e-107	315.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HY1P@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_565662_1	1249975.JQLP01000001_gene3212	2.62e-19	85.9	COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_678686_2	926559.JoomaDRAFT_1169	6.91e-68	221.0	COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,1HZNM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_1130620_1	1122225.AULQ01000005_gene2484	1e-12	65.1	COG1595@1|root,COG1595@2|Bacteria,4NIB5@976|Bacteroidetes,1I0JQ@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
k59_1130620_2	1353276.JADR01000003_gene2780	2.3e-32	119.0	2BU5H@1|root,32PEF@2|Bacteria,4NQ6Q@976|Bacteroidetes,1I3JW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_847853_1	1123514.KB905901_gene133	1.44e-13	69.3	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,46009@72273|Thiotrichales	72273|Thiotrichales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_847853_2	1123355.JHYO01000006_gene2299	1.44e-07	54.7	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,36X7S@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
k59_847853_3	440512.C211_12811	1.26e-09	60.1	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1525883_1	411154.GFO_2869	4.14e-83	255.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1HXZB@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_1525883_2	1121931.AUHG01000011_gene1653	6.29e-48	156.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_170329_1	1123228.AUIH01000015_gene535	1.28e-82	260.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XHV2@135619|Oceanospirillales	135619|Oceanospirillales	E	acetolactate synthase	ilvB-1	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_170329_2	1195246.AGRI_10166	3.17e-10	57.8	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,466IV@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1906,iECNA114_1301.ECNA114_0072,iEcSMS35_1347.EcSMS35_0084,iG2583_1286.G2583_0082,iSFxv_1172.SFxv_0077,iUTI89_1310.UTI89_C0086	ACT,ACT_5,ALS_ss_C
k59_1582423_1	273068.TTE1213	1.06e-34	136.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,42EJU@68295|Thermoanaerobacterales	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1356321_1	1123518.ARWI01000001_gene983	8.97e-93	281.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,45ZS4@72273|Thiotrichales	72273|Thiotrichales	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_226848_2	616991.JPOO01000001_gene3945	1.14e-42	145.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCK@117743|Flavobacteriia,23G1J@178469|Arenibacter	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1187082_2	313595.P700755_003033	1.43e-33	120.0	2EEZE@1|root,338SK@2|Bacteria,4NVC1@976|Bacteroidetes,1I5BS@117743|Flavobacteriia,4C4CS@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1187082_3	1392490.JHZX01000001_gene2278	8.23e-158	449.0	COG0583@1|root,COG0583@2|Bacteria,4NGHS@976|Bacteroidetes,1HXYJ@117743|Flavobacteriia	976|Bacteroidetes	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_170359_1	425104.Ssed_0226	5.17e-100	306.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,1RNRS@1236|Gammaproteobacteria,2Q932@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008683,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0019842,GO:0030976,GO:0036094,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070204,GO:0071704,GO:0097159,GO:1901363,GO:1901576,GO:1901661,GO:1901663,GO:1901681	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_2301	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k59_1356337_1	1178825.ALIH01000001_gene2310	1.7e-110	329.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1HYS5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_170362_1	1123514.KB905900_gene2057	1.81e-72	221.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,460QW@72273|Thiotrichales	72273|Thiotrichales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_170362_2	1123514.KB905900_gene2056	1e-66	214.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,45ZQK@72273|Thiotrichales	72273|Thiotrichales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_284842_2	90814.KL370891_gene1461	3.49e-20	87.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,460G3@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_623861_1	399741.Spro_4920	2.06e-05	46.6	COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,40472@613|Serratia	1236|Gammaproteobacteria	OU	Belongs to the peptidase S14 family	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease,Mu-like_gpT
k59_623861_2	1476902.A0A067ZJA4_9CAUD	4.35e-193	551.0	4QAZJ@10239|Viruses,4QX3R@35237|dsDNA viruses  no RNA stage,4QPFF@28883|Caudovirales,4QJS9@10662|Myoviridae	10662|Myoviridae	S	virion assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1470470_1	1415779.JOMH01000001_gene2479	2.09e-28	109.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1X3FN@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_1470470_2	1123228.AUIH01000001_gene1360	5.87e-88	265.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1XH37@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_284843_1	1380600.AUYN01000001_gene2698	2.56e-177	499.0	COG2035@1|root,COG2035@2|Bacteria,4NDU1@976|Bacteroidetes,1HYB3@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF368
k59_284843_2	1380600.AUYN01000001_gene2699	1.64e-140	400.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia	976|Bacteroidetes	E	Shikimate	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
k59_1244582_1	710687.KI912270_gene2635	3.38e-25	108.0	COG3209@1|root,COG4254@1|root,COG5184@1|root,COG3209@2|Bacteria,COG4254@2|Bacteria,COG5184@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
k59_1584072_1	411684.HPDFL43_01375	2.62e-30	113.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2TT7P@28211|Alphaproteobacteria,43IC8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	ygbJ	-	1.1.1.411	ko:K08319	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_1301801_1	504487.JCM19302_222	2.87e-139	402.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1HX7A@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_623884_1	305900.GV64_15820	6.2e-73	243.0	COG1061@1|root,COG1061@2|Bacteria,1QCQA@1224|Proteobacteria	1224|Proteobacteria	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_1640748_1	1123518.ARWI01000001_gene2111	2.73e-77	245.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,460HX@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_1640748_2	90814.KL370891_gene1544	4.07e-81	251.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,45ZNF@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_454480_1	1121931.AUHG01000015_gene1195	9.97e-51	169.0	2EEDZ@1|root,33881@2|Bacteria,4NUTS@976|Bacteroidetes,1I60B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_849109_1	1137281.D778_02395	4.15e-157	453.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,1HWMR@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_849109_2	1197477.IA57_07285	8.05e-48	157.0	COG3117@1|root,COG3117@2|Bacteria,4NN1J@976|Bacteroidetes,1I28B@117743|Flavobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
k59_793243_1	411154.GFO_1562	5.93e-115	335.0	COG1360@1|root,COG1360@2|Bacteria,4NHDJ@976|Bacteroidetes,1HWS7@117743|Flavobacteriia	976|Bacteroidetes	N	flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1019336_2	207954.MED92_13798	4.08e-42	150.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XI3D@135619|Oceanospirillales	135619|Oceanospirillales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_962677_1	929558.SMGD1_1768	1.46e-93	301.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2YNJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cznA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_228487_1	1121931.AUHG01000010_gene24	3.15e-128	400.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_1527538_1	1123514.KB905899_gene700	7.92e-81	250.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,4625S@72273|Thiotrichales	72273|Thiotrichales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_228503_1	929558.SMGD1_2479	5.21e-45	153.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2YN2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_1640802_1	945713.IALB_1022	1.62e-15	76.6	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH,WG_beta_rep
k59_341053_1	1565129.JSFF01000008_gene2687	1.05e-37	132.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,2Q8MI@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1949)	yigZ	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1949,UPF0029
k59_1301894_1	319224.Sputcn32_1019	8.04e-86	260.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,2Q8T7@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1470581_1	1178825.ALIH01000001_gene2673	1.45e-93	282.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1470581_2	1178825.ALIH01000001_gene2672	1.29e-91	271.0	COG0544@1|root,COG0544@2|Bacteria,4PMNC@976|Bacteroidetes,1IJVR@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_1470581_3	1121889.AUDM01000014_gene1930	8.49e-09	55.8	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,2NTC4@237|Flavobacterium	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_1470586_1	1380391.JIAS01000011_gene5309	4.4e-11	69.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JQPJ@204441|Rhodospirillales	204441|Rhodospirillales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k59_1697135_1	572480.Arnit_0836	1.06e-67	208.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,42U6Y@68525|delta/epsilon subdivisions,2YRSZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_1697135_2	1123326.JFBL01000002_gene1603	5.06e-23	95.9	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2YR33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_1301914_1	323850.Shew_0515	5.55e-94	291.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,1SJTB@1236|Gammaproteobacteria,2Q8HW@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_454560_1	1250005.PHEL85_3271	6.83e-270	748.0	COG1012@1|root,COG1012@2|Bacteria,4NEQ2@976|Bacteroidetes,1HYQ7@117743|Flavobacteriia,3VVU2@52959|Polaribacter	976|Bacteroidetes	C	Aldehyde dehydrogenase family	gapN	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_454560_2	1380600.AUYN01000009_gene1171	1.63e-171	487.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_906457_1	616991.JPOO01000001_gene4055	7.89e-41	143.0	COG3464@1|root,COG3464@2|Bacteria,4NFK7@976|Bacteroidetes,1HX8S@117743|Flavobacteriia,23I4B@178469|Arenibacter	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k59_906457_2	929556.Solca_3186	2.6e-26	108.0	COG3464@1|root,COG3464@2|Bacteria,4NFK7@976|Bacteroidetes,1INXR@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k59_906457_3	1286632.P278_28500	2.53e-67	211.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,1I2PJ@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_906457_4	1380600.AUYN01000009_gene1221	3.01e-98	299.0	COG3712@1|root,COG3712@2|Bacteria,4NICU@976|Bacteroidetes,1HZXH@117743|Flavobacteriia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_906457_5	1380600.AUYN01000009_gene1220	1.62e-98	320.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1584194_1	1178825.ALIH01000001_gene2366	5.89e-78	242.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1301937_1	1353537.TP2_13750	1.11e-26	106.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria,2XKM9@285107|Thioclava	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_1301937_2	1353528.DT23_03420	2.29e-71	220.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2TTCE@28211|Alphaproteobacteria,2XMJM@285107|Thioclava	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
k59_1188729_1	1121931.AUHG01000012_gene2684	4.45e-120	367.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_285001_1	65393.PCC7424_5770	3.72e-103	306.0	COG1682@1|root,COG1682@2|Bacteria,1G23R@1117|Cyanobacteria,3KGYJ@43988|Cyanothece	1117|Cyanobacteria	P	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
k59_736960_1	411154.GFO_3039	1.61e-53	174.0	COG0810@1|root,COG0810@2|Bacteria,4NN8A@976|Bacteroidetes,1I18J@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_736960_2	1121931.AUHG01000010_gene294	2.93e-36	123.0	2E9F6@1|root,333NH@2|Bacteria,4NUX1@976|Bacteroidetes,1I56U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
k59_1132364_1	749222.Nitsa_0202	1.09e-40	141.0	COG0622@1|root,COG0622@2|Bacteria,1NPH4@1224|Proteobacteria,42TB8@68525|delta/epsilon subdivisions,2YPHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_1132364_2	563040.Saut_0124	2.35e-31	116.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1474650_2	929558.SMGD1_1563	4.39e-228	634.0	COG0460@1|root,COG2716@1|root,COG0460@2|Bacteria,COG2716@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2YMUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_966576_1	313612.L8106_21734	2.32e-32	127.0	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1G2A0@1117|Cyanobacteria,1H8JI@1150|Oscillatoriales	1117|Cyanobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_9,Response_reg
k59_966576_3	563040.Saut_1746	3.1e-28	103.0	2B2IW@1|root,31V40@2|Bacteria,1QSZI@1224|Proteobacteria,4332K@68525|delta/epsilon subdivisions,2YSGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_966576_4	709032.Sulku_1811	3.63e-68	208.0	2BMN0@1|root,32G77@2|Bacteria,1Q0X8@1224|Proteobacteria,42SM0@68525|delta/epsilon subdivisions,2YPGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_288817_1	498211.CJA_1800	3.5e-10	60.1	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1FH3K@10|Cellvibrio	1236|Gammaproteobacteria	J	S4 RNA-binding domain	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_288817_2	1123228.AUIH01000026_gene3904	3.21e-20	94.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1XJRF@135619|Oceanospirillales	135619|Oceanospirillales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_1135724_1	929558.SMGD1_2381	8.08e-129	379.0	COG1397@1|root,COG1397@2|Bacteria,1Q98F@1224|Proteobacteria,42U7M@68525|delta/epsilon subdivisions,2YTJI@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_62981_1	1232683.ADIMK_3296	3.21e-21	92.4	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,466ZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	dsbA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
k59_458561_1	504487.JCM19302_3167	7.61e-36	125.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1I17M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_458561_2	1178825.ALIH01000001_gene2611	4.58e-53	179.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_232626_1	1406840.Q763_09725	3.2e-67	226.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,1HZXU@117743|Flavobacteriia,2NTUX@237|Flavobacterium	976|Bacteroidetes	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
k59_232626_2	655815.ZPR_3455	1.33e-93	273.0	2C8HR@1|root,32RM8@2|Bacteria,4NT7Z@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232626_3	1406840.Q763_09715	3.24e-73	219.0	2DMI6@1|root,32RQ4@2|Bacteria,4NT0J@976|Bacteroidetes,1II7Z@117743|Flavobacteriia,2NWX3@237|Flavobacterium	976|Bacteroidetes	S	Carbamoyl phosphate synthetase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4134
k59_62983_1	317025.Tcr_0872	1.56e-93	278.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,46080@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_6099_1	1380600.AUYN01000009_gene1677	4.79e-131	377.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_853046_1	1123514.KB905901_gene18	1.79e-27	103.0	2EGR8@1|root,33AHD@2|Bacteria,1N6Z8@1224|Proteobacteria,1SDY4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	FeoC like transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FeoC
k59_853046_2	1123518.ARWI01000001_gene1839	8.71e-08	52.4	2F0VY@1|root,33TXM@2|Bacteria,1NVBB@1224|Proteobacteria,1SNJU@1236|Gammaproteobacteria,4629H@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_740524_1	1249480.B649_05415	6.37e-79	263.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_288837_1	702450.CUW_1333	3.71e-13	74.3	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,3VT7V@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
k59_1248442_1	929558.SMGD1_1288	1.86e-42	150.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_1248442_2	1172190.M947_02420	1.91e-34	130.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2YN81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	flgE	GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flagellin_IN,Flg_bb_rod,Flg_bbr_C
k59_1644660_1	1250278.JQNQ01000001_gene2759	4.07e-30	115.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_1644660_2	1121931.AUHG01000016_gene1032	8.79e-75	233.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1HX39@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_1757682_2	945713.IALB_1565	4.86e-39	135.0	COG0319@1|root,COG0319@2|Bacteria	2|Bacteria	C	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029	-	-	-	UPF0054
k59_909969_1	1380600.AUYN01000009_gene1486	1.21e-172	487.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1HY2Y@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_909969_2	1121912.AUHD01000005_gene1698	2.07e-149	425.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1HYHC@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_909969_3	1178825.ALIH01000020_gene2725	2.32e-98	293.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_909969_4	1347342.BN863_27620	3.47e-118	354.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_63010_1	1333856.L686_10145	1.06e-26	108.0	COG0503@1|root,COG0503@2|Bacteria,1QUX8@1224|Proteobacteria,1S3HT@1236|Gammaproteobacteria,1Z2JQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_63010_2	90814.KL370891_gene409	4.3e-93	297.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,461K4@72273|Thiotrichales	72273|Thiotrichales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k59_1078857_1	1123518.ARWI01000001_gene1565	6.2e-27	105.0	COG3619@1|root,COG3619@2|Bacteria,1RB5Q@1224|Proteobacteria,1RRG5@1236|Gammaproteobacteria,4619N@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
k59_1078857_2	1123514.KB905900_gene2208	3.1e-138	399.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,460HT@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_1135757_1	1172190.M947_02370	2.12e-12	64.7	2AIM2@1|root,319HK@2|Bacteria,1Q2ST@1224|Proteobacteria,42W74@68525|delta/epsilon subdivisions,2YQAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1135757_2	563040.Saut_0050	1.39e-69	213.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2YPE3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_1306057_1	411154.GFO_2552	1.08e-135	398.0	COG1292@1|root,COG1292@2|Bacteria,4NEIW@976|Bacteroidetes,1HXKK@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_344789_1	1123514.KB905899_gene682	6.51e-120	355.0	COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
k59_1361281_1	1250006.JHZZ01000001_gene2235	4.05e-181	548.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,3VX3M@52959|Polaribacter	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_629844_1	563040.Saut_1337	3.51e-28	109.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_629844_2	929558.SMGD1_2474	6.44e-57	181.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2YNX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iIT341.HP1016	CDP-OH_P_transf
k59_1308111_1	1541065.JRFE01000035_gene2800	7.88e-27	116.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4585@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4585@2|Bacteria,1GD97@1117|Cyanobacteria,3VI2Q@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,PAS_9,Pkinase,Response_reg
k59_290825_1	1249997.JHZW01000001_gene4113	1.73e-14	71.6	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1HY93@117743|Flavobacteriia,2PGYE@252356|Maribacter	976|Bacteroidetes	E	Proline racemase	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_290825_2	1380600.AUYN01000006_gene462	2.1e-230	642.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1HYMG@117743|Flavobacteriia	976|Bacteroidetes	E	Glycine D-amino acid	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
k59_290825_3	1380600.AUYN01000001_gene2616	2.05e-145	419.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1HYBF@117743|Flavobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_290825_4	1380600.AUYN01000006_gene460	4.88e-74	224.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1I2TG@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_799466_1	1172190.M947_00235	1.84e-59	201.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YNJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C,TrkA_N
k59_1759703_1	1197477.IA57_09705	2.39e-50	164.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia	976|Bacteroidetes	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k59_1759703_2	985255.APHJ01000028_gene939	2.3e-46	149.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1I42P@117743|Flavobacteriia,2P702@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
k59_1759703_3	1380600.AUYN01000003_gene92	5.27e-54	189.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1532899_1	1380600.AUYN01000009_gene994	4.13e-115	338.0	COG2885@1|root,COG2885@2|Bacteria,4NH36@976|Bacteroidetes,1HWN0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1532899_2	504487.JCM19302_1531	8.4e-68	213.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k59_1759710_1	1168067.JAGP01000001_gene1255	5.47e-290	798.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,4605B@72273|Thiotrichales	72273|Thiotrichales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1759712_1	1122918.KB907296_gene4327	1.38e-25	110.0	COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4HE8W@91061|Bacilli,26U7B@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k59_8100_1	1250005.PHEL85_1102	1.81e-214	619.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia,3VX58@52959|Polaribacter	976|Bacteroidetes	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_968107_1	1046627.BZARG_720	8.74e-13	63.2	2EGQH@1|root,33AGN@2|Bacteria,4NY0P@976|Bacteroidetes,1I6DX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_968107_2	504487.JCM19302_2265	5.27e-61	199.0	COG2979@1|root,COG2979@2|Bacteria,4PKCN@976|Bacteroidetes,1IJ7M@117743|Flavobacteriia	976|Bacteroidetes	S	LETM1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LETM1
k59_911924_1	1121931.AUHG01000012_gene2879	9.23e-116	346.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
k59_8118_1	946483.Cenrod_2633	2.15e-40	153.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
k59_1420402_1	1237149.C900_03332	1.74e-05	45.8	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
k59_1420402_2	1237149.C900_03331	1.62e-59	189.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_573313_1	1123518.ARWI01000001_gene2132	4.36e-72	218.0	COG3793@1|root,COG3793@2|Bacteria	2|Bacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	TerB,zinc_ribbon_15
k59_573313_2	317025.Tcr_0599	2.09e-97	301.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_742462_1	1380600.AUYN01000007_gene3306	5.63e-28	105.0	COG2318@1|root,COG2318@2|Bacteria,4NSEY@976|Bacteroidetes,1I2YX@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_742462_2	1380600.AUYN01000007_gene3307	7.59e-72	225.0	28JBH@1|root,2Z967@2|Bacteria,4NNHF@976|Bacteroidetes,1HYEA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
k59_742462_3	1380600.AUYN01000007_gene3309	1.19e-128	371.0	COG3047@1|root,COG3047@2|Bacteria,4NH9T@976|Bacteroidetes,1HYYP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_8126_1	1123514.KB905899_gene2034	1.57e-105	328.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,461PB@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1476812_1	572480.Arnit_3034	3.26e-83	266.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YRFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1080850_1	1267533.KB906734_gene4055	6.34e-17	85.1	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
k59_8139_2	572480.Arnit_1971	5.82e-117	346.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42QH4@68525|delta/epsilon subdivisions,2YNGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_234808_1	1123518.ARWI01000001_gene2134	1.74e-57	179.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,1SCTJ@1236|Gammaproteobacteria,4619K@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
k59_234808_2	1123514.KB905899_gene554	8.52e-85	252.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,463KC@72273|Thiotrichales	72273|Thiotrichales	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,TAT_signal
k59_234808_3	1123514.KB905899_gene555	9.17e-35	120.0	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,1SD5N@1236|Gammaproteobacteria,461B4@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1080853_1	563040.Saut_1252	4.42e-20	86.7	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2YNM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1532950_1	1250005.PHEL85_2147	2.9e-56	183.0	2BRVQ@1|root,32KVY@2|Bacteria,4NRTS@976|Bacteroidetes,1I3EB@117743|Flavobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1532950_2	1250005.PHEL85_2152	6.92e-96	285.0	COG0664@1|root,COG0664@2|Bacteria,4NMVR@976|Bacteroidetes,1I1WA@117743|Flavobacteriia,3VXGQ@52959|Polaribacter	976|Bacteroidetes	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
k59_1532950_3	313603.FB2170_14948	1.21e-248	691.0	COG2067@1|root,COG2067@2|Bacteria,4PFMQ@976|Bacteroidetes,1HYJE@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_65147_1	1172190.M947_01205	3.83e-91	276.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_65147_2	929558.SMGD1_2773	4.98e-40	139.0	2AJE1@1|root,319ZU@2|Bacteria,1Q4J6@1224|Proteobacteria,42U7R@68525|delta/epsilon subdivisions,2YQ63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1759783_1	1380600.AUYN01000007_gene3039	2.37e-84	253.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1I2XD@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
k59_1308208_2	1178825.ALIH01000005_gene342	1.29e-132	377.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1HX6X@117743|Flavobacteriia	976|Bacteroidetes	Q	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k59_1308208_3	1484460.JSWG01000008_gene1976	8.66e-17	73.9	COG2198@1|root,COG2198@2|Bacteria,4NVS6@976|Bacteroidetes,1I5MU@117743|Flavobacteriia	976|Bacteroidetes	T	(Hpt) domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_178336_1	1410608.JNKX01000007_gene978	6.79e-20	91.3	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,2FPCZ@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1532974_1	1123514.KB905899_gene1023	5.87e-40	138.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,460FS@72273|Thiotrichales	72273|Thiotrichales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
k59_1532974_2	1168067.JAGP01000001_gene1024	1.66e-66	207.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,460UI@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_911990_1	1165841.SULAR_01713	1.62e-77	244.0	COG0811@1|root,COG0811@2|Bacteria,1QUIX@1224|Proteobacteria,42MTG@68525|delta/epsilon subdivisions,2YMAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_404044_1	930169.B5T_00161	9.82e-73	221.0	28V8Y@1|root,2ZHBX@2|Bacteria,1RD5G@1224|Proteobacteria,1S39W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Methylamine dehydrogenase light chain	-	-	1.4.9.1	ko:K15228	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_L
k59_742524_1	1121931.AUHG01000011_gene2213	2.86e-73	229.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k59_1137713_1	90814.KL370891_gene1681	8.81e-143	424.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,46089@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_1080905_1	411154.GFO_1557	4.17e-70	219.0	COG3121@1|root,COG3121@2|Bacteria,4NK7D@976|Bacteroidetes,1I142@117743|Flavobacteriia	976|Bacteroidetes	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	PapD_N
k59_1080905_2	411154.GFO_1556	1.17e-06	50.8	COG2911@1|root,COG2911@2|Bacteria,4NKIP@976|Bacteroidetes,1I0IX@117743|Flavobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
k59_460749_1	1296416.JACB01000033_gene2103	2.12e-42	159.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2YK9G@290174|Aquimarina	976|Bacteroidetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE
k59_1192417_1	1408813.AYMG01000038_gene270	8.62e-59	203.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	2.1.1.72	ko:K03427,ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,HSDR_N_2,Methylase_S,N6_Mtase,TaqI_C
k59_1363265_1	387093.SUN_2269	6.41e-117	342.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_1250711_1	326298.Suden_0963	1.22e-106	312.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_968189_1	1122179.KB890469_gene596	3.52e-93	307.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,Reg_prop,Response_reg,Y_Y_Y
k59_1703112_1	1168067.JAGP01000001_gene1706	1.8e-41	145.0	COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAES@1236|Gammaproteobacteria,462TI@72273|Thiotrichales	72273|Thiotrichales	O	DNA-J related protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DnaJ
k59_1703112_2	1123518.ARWI01000001_gene2339	9.32e-233	648.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,45ZW7@72273|Thiotrichales	72273|Thiotrichales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1192418_1	504487.JCM19302_1910	2.51e-38	140.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_1192418_2	983544.Lacal_0514	1.83e-100	299.0	COG3332@1|root,COG3332@2|Bacteria,4NMN7@976|Bacteroidetes,1I1KH@117743|Flavobacteriia	976|Bacteroidetes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
k59_178379_1	1380600.AUYN01000009_gene1204	3.3e-280	768.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1HXRK@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k59_178379_2	143224.JQMD01000002_gene2293	4.25e-49	164.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1HXPZ@117743|Flavobacteriia	976|Bacteroidetes	EH	sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_1137738_1	755732.Fluta_2513	2e-07	52.8	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1HYKY@117743|Flavobacteriia,2PA9U@246874|Cryomorphaceae	976|Bacteroidetes	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_1137738_2	1380600.AUYN01000009_gene1779	1.48e-101	296.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1HY9X@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_1137738_3	1197477.IA57_08045	0.000761	40.8	COG5343@1|root,COG5343@2|Bacteria,4NH0S@976|Bacteroidetes,1HY07@117743|Flavobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
k59_1703114_1	1172190.M947_06490	2.08e-175	509.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2YMPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1759844_1	563040.Saut_1394	1.71e-98	306.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_516550_1	572480.Arnit_1960	6.36e-110	327.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1476919_1	224911.27354253	1.12e-45	155.0	COG1028@1|root,COG1028@2|Bacteria,1Q3GM@1224|Proteobacteria,2U25Q@28211|Alphaproteobacteria,3JWV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1308287_1	563040.Saut_2126	5.1e-57	182.0	COG0421@1|root,COG0421@2|Bacteria,1PD55@1224|Proteobacteria,42UAB@68525|delta/epsilon subdivisions,2YPTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1250736_1	1123037.AUDE01000008_gene633	9.09e-68	212.0	2BAFY@1|root,323WE@2|Bacteria,4NQ3E@976|Bacteroidetes,1I30F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1250736_2	1380600.AUYN01000009_gene2055	3.74e-98	288.0	COG1595@1|root,COG1595@2|Bacteria,4NFXX@976|Bacteroidetes,1HZT5@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1250736_3	504487.JCM19302_3009	1.36e-197	571.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_8245_1	929558.SMGD1_0906	1.18e-76	235.0	COG3022@1|root,COG3022@2|Bacteria,1Q5IV@1224|Proteobacteria,42QYB@68525|delta/epsilon subdivisions,2YNY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_8245_2	929558.SMGD1_0905	1.58e-40	142.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
k59_1646881_1	643867.Ftrac_1609	6.93e-62	206.0	COG2203@1|root,COG2203@2|Bacteria,4P0X3@976|Bacteroidetes,47TEQ@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_404125_1	1380600.AUYN01000001_gene2349	4.07e-86	262.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_1648505_3	1178825.ALIH01000011_gene19	2.28e-61	189.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1I2XZ@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
k59_1648505_4	504487.JCM19302_3465	1.88e-73	225.0	COG0242@1|root,COG0242@2|Bacteria,4NPNS@976|Bacteroidetes,1I2ND@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	DUF1684,Pep_deformylase
k59_1139334_1	1117314.PCIT_14179	2.07e-77	256.0	COG0507@1|root,COG0507@2|Bacteria,1R41A@1224|Proteobacteria,1RZ63@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,DUF4145,NERD,UvrD_C_2
k59_1761624_1	317025.Tcr_1249	1.31e-15	76.3	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,460QB@72273|Thiotrichales	72273|Thiotrichales	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_1761624_2	317025.Tcr_1250	5.62e-54	181.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1SBFD@1236|Gammaproteobacteria,461AX@72273|Thiotrichales	72273|Thiotrichales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1310064_1	305700.B447_09138	2.03e-153	443.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,2KV4V@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1534707_1	326298.Suden_1042	6.27e-32	117.0	COG2834@1|root,COG2834@2|Bacteria,1PQ15@1224|Proteobacteria,42WEH@68525|delta/epsilon subdivisions,2YPW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_1534707_2	1172190.M947_10595	1.13e-25	105.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_405829_1	504487.JCM19302_904	5.64e-51	167.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1HXX3@117743|Flavobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_405829_2	641526.ADIWIN_1591	3.68e-31	110.0	COG1476@1|root,COG1476@2|Bacteria,4NV53@976|Bacteroidetes,1I527@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_405829_3	641526.ADIWIN_1592	9.76e-09	53.1	2E6RI@1|root,331BM@2|Bacteria,4NVRD@976|Bacteroidetes,1I5B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_348580_1	1121931.AUHG01000010_gene188	4.12e-108	333.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HX6P@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_688736_1	572480.Arnit_0159	5.22e-43	148.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42RFS@68525|delta/epsilon subdivisions,2YP62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1704873_1	207954.MED92_10459	2.47e-21	91.7	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XIS5@135619|Oceanospirillales	135619|Oceanospirillales	C	alcohol dehydrogenase	-	-	-	ko:K19954	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
k59_1704873_2	323850.Shew_3716	2.27e-101	296.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q9IP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM cytochrome c, class I	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1139360_1	1120966.AUBU01000001_gene1039	9.68e-42	157.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y
k59_9952_1	411154.GFO_2746	8.23e-123	378.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_631770_1	411154.GFO_1766	2.39e-125	379.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_913786_1	1121931.AUHG01000001_gene3103	1.02e-125	373.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_1252520_1	425104.Ssed_1191	1.99e-47	154.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,2QCAS@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_1310143_1	1476902.A0A097P6S4_9CAUD	6.21e-14	75.9	4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses  no RNA stage,4QPBY@28883|Caudovirales,4QHYN@10662|Myoviridae	10662|Myoviridae	S	amidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9990_1	1172190.M947_09535	1.08e-100	314.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1027410_1	909613.UO65_1176	2.37e-05	51.6	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria,4E1QS@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_123051_1	1537915.JU57_06740	8.34e-110	324.0	COG0535@1|root,COG0535@2|Bacteria,1Q4MU@1224|Proteobacteria,42U7S@68525|delta/epsilon subdivisions,2YRZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_123051_2	635013.TherJR_2784	6.58e-55	183.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia,262IY@186807|Peptococcaceae	186801|Clostridia	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_123051_3	1537915.JU57_06730	2.9e-40	140.0	COG0535@1|root,COG0535@2|Bacteria,1PDXU@1224|Proteobacteria,42NVS@68525|delta/epsilon subdivisions,2YNBB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_969496_1	1178825.ALIH01000006_gene1423	6.52e-100	292.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_857134_1	1123514.KB905899_gene878	2.6e-06	48.5	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,4628I@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_857134_2	1123514.KB905899_gene877	3.19e-81	245.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,462BC@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_857134_3	1123514.KB905899_gene876	1.21e-110	323.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,4611E@72273|Thiotrichales	72273|Thiotrichales	L	Belongs to the DnaA family. HdA subfamily	-	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
k59_1534800_1	1121931.AUHG01000010_gene719	1.21e-151	445.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_631818_1	1121931.AUHG01000010_gene375	3.61e-21	89.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1I18P@117743|Flavobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
k59_631818_2	411154.GFO_3388	9.59e-143	410.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_744317_1	1278309.KB907110_gene3173	1.1e-07	57.4	COG1192@1|root,COG1192@2|Bacteria,1MVEZ@1224|Proteobacteria,1RPWA@1236|Gammaproteobacteria,1XI4F@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_631819_1	1380600.AUYN01000001_gene2518	6.04e-70	214.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1I1Z5@117743|Flavobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_631819_2	1380600.AUYN01000001_gene2519	4.2e-137	391.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1HXGW@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_631819_3	1380600.AUYN01000001_gene2520	1.88e-113	331.0	COG0741@1|root,COG0741@2|Bacteria,4NMIF@976|Bacteroidetes,1I1GE@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan-binding protein LysM	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_631819_4	1380600.AUYN01000001_gene2521	1.1e-33	124.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
k59_348674_1	411154.GFO_3415	2.01e-06	48.5	COG0457@1|root,COG4547@1|root,COG0457@2|Bacteria,COG4547@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia	976|Bacteroidetes	H	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_348674_2	411154.GFO_3416	4.17e-98	301.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_67089_1	644107.SL1157_A0172	4.51e-19	85.5	COG1653@1|root,COG1653@2|Bacteria,1MXZJ@1224|Proteobacteria,2TSFY@28211|Alphaproteobacteria,4NBPJ@97050|Ruegeria	28211|Alphaproteobacteria	G	Extracellular solute-binding protein, family 1	aglE	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
k59_67089_2	1123228.AUIH01000021_gene105	5.26e-28	110.0	COG1175@1|root,COG1175@2|Bacteria,1MXK1@1224|Proteobacteria,1S09U@1236|Gammaproteobacteria,1XNCM@135619|Oceanospirillales	135619|Oceanospirillales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
k59_1478835_1	90814.KL370891_gene239	9.97e-50	159.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_1478835_2	90814.KL370891_gene240	2.1e-147	416.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,45ZXA@72273|Thiotrichales	72273|Thiotrichales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_1478835_3	90814.KL370891_gene241	1.91e-20	84.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,460I6@72273|Thiotrichales	72273|Thiotrichales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_518461_1	391603.FBALC1_03442	4.68e-114	341.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_180323_1	1122179.KB890447_gene194	2.38e-39	142.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_180323_2	1197477.IA57_02075	2.48e-136	406.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_10044_1	7070.TC001481-PA	3.68e-32	126.0	COG2801@1|root,KOG0017@2759|Eukaryota,39ZX7@33154|Opisthokonta,3BQ45@33208|Metazoa,3D40D@33213|Bilateria,4208T@6656|Arthropoda	33208|Metazoa	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	Chromo,rve
k59_1478848_1	1123518.ARWI01000001_gene2121	8.89e-130	379.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,45ZZ3@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_292897_1	983545.Glaag_4025	2.07e-08	54.7	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,46667@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
k59_236906_1	1415778.JQMM01000001_gene2075	2.11e-21	89.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1J4TT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_236906_2	1027273.GZ77_05675	6.97e-36	132.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1252595_1	392500.Swoo_0393	6.64e-80	257.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1SZS1@1236|Gammaproteobacteria,2Q9VB@267890|Shewanellaceae	1236|Gammaproteobacteria	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_236909_1	90813.JQMT01000001_gene22	5.45e-47	151.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,463RH@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L31	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_236909_2	1123518.ARWI01000001_gene1690	8.57e-273	749.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,45ZQQ@72273|Thiotrichales	72273|Thiotrichales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1027494_1	82654.Pse7367_3368	8.42e-11	67.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1G1Z9@1117|Cyanobacteria,1H9QB@1150|Oscillatoriales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	-	ko:K13486	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	CheR,TPR_1,TPR_8
k59_1027494_2	529507.PMI1663	2.22e-14	75.5	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,3Z1JT@583|Proteus	1236|Gammaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_180349_1	1380600.AUYN01000009_gene1539	7.62e-148	428.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,1HWNJ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2TM,His_kinase
k59_180349_2	1380600.AUYN01000009_gene1538	1.49e-99	292.0	2C9AB@1|root,2ZB91@2|Bacteria,4NKQ3@976|Bacteroidetes,1I0P5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_575361_1	1121875.KB907546_gene2405	5.34e-51	172.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,1I0SF@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
k59_575361_2	1137281.D778_01800	0.0	963.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_348727_1	391587.KAOT1_18267	1.69e-19	87.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_348727_2	504487.JCM19302_1436	1.74e-138	402.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_857224_1	945713.IALB_2238	2.06e-72	224.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_1478889_2	1150621.SMUL_1515	4.4e-29	114.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42MJS@68525|delta/epsilon subdivisions,2YNPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_292929_1	94122.Shewana3_3338	1.31e-07	53.1	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q8ZE@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_292929_2	323850.Shew_0764	1.03e-119	346.0	COG1180@1|root,COG1180@2|Bacteria,1RA4Z@1224|Proteobacteria,1S34Q@1236|Gammaproteobacteria,2QAFU@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
k59_292929_3	1336233.JAEH01000010_gene2669	6.49e-46	164.0	COG3852@1|root,COG3852@2|Bacteria,1NX8K@1224|Proteobacteria,1SQC3@1236|Gammaproteobacteria,2Q8K0@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9
k59_1139521_1	207954.MED92_17793	1.17e-52	181.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1S1PI@1236|Gammaproteobacteria,1XRTG@135619|Oceanospirillales	135619|Oceanospirillales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
k59_1422325_1	404589.Anae109_2160	1.1e-33	129.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42NBN@68525|delta/epsilon subdivisions,2WK8A@28221|Deltaproteobacteria,2YU28@29|Myxococcales	28221|Deltaproteobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_969574_2	655815.ZPR_3762	7.91e-32	121.0	COG0415@1|root,COG0415@2|Bacteria,4NDW0@976|Bacteroidetes,1HWUN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phrB3	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_969574_3	1121931.AUHG01000011_gene1801	1.35e-57	190.0	COG0415@1|root,COG0415@2|Bacteria,4NDW0@976|Bacteroidetes,1HWUN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phrB3	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1761825_1	1353276.JADR01000003_gene2869	7.7e-10	57.8	2EFU3@1|root,339K7@2|Bacteria,4NY7Q@976|Bacteroidetes,1I6UJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1193751_1	563040.Saut_1732	8.7e-150	427.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2YNZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_1193751_2	326298.Suden_1670	1.71e-176	511.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_631915_1	572480.Arnit_0491	2.38e-128	387.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_292952_1	929558.SMGD1_1443	9.89e-143	438.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_180391_1	29495.EA26_19285	1.5e-40	144.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1XWBQ@135623|Vibrionales	135623|Vibrionales	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_180391_2	637905.SVI_3976	9.89e-12	61.6	COG3339@1|root,COG3339@2|Bacteria,1MZR5@1224|Proteobacteria,1S912@1236|Gammaproteobacteria,2QCEJ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_1252650_1	323850.Shew_0543	2.59e-74	229.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,2Q8YY@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	SO3905	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1252650_2	323850.Shew_0542	3.87e-89	269.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,2Q93N@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k59_462853_1	323850.Shew_3749	1.17e-66	204.0	COG4319@1|root,COG4319@2|Bacteria,1MZRB@1224|Proteobacteria,1SC2M@1236|Gammaproteobacteria,2QBK7@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_67191_1	1121931.AUHG01000010_gene808	4.48e-213	619.0	COG0477@1|root,COG0477@2|Bacteria,4PM7N@976|Bacteroidetes,1IJKR@117743|Flavobacteriia	976|Bacteroidetes	EGP	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_180412_1	411154.GFO_2924	1.36e-126	386.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,1HZ3X@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
k59_913930_1	1175654.A0A0S0NDG6_9CAUD	6.71e-77	239.0	4QDKA@10239|Viruses,4QUPP@35237|dsDNA viruses  no RNA stage,4QPPG@28883|Caudovirales,4QMZH@10699|Siphoviridae	10699|Siphoviridae	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_913930_2	1175654.A0A0S0MVP1_9CAUD	5.69e-232	660.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae	10699|Siphoviridae	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_913930_3	1175654.A0A0S0N8V2_9CAUD	1.72e-17	84.7	4QE1S@10239|Viruses,4QX6S@35237|dsDNA viruses  no RNA stage,4QRC4@28883|Caudovirales,4QN20@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_859781_1	637905.SVI_0263	1.14e-50	166.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,2Q9KJ@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein GntR HTH	pdhR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K05799,ko:K11474	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k59_1481543_1	1537917.JU82_08555	1.07e-48	160.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42RV5@68525|delta/epsilon subdivisions,2YP89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1481543_2	929558.SMGD1_1186	2.44e-57	184.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1595042_1	1380600.AUYN01000006_gene733	1.45e-31	115.0	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,1I2TS@117743|Flavobacteriia	976|Bacteroidetes	J	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_1595042_2	1380600.AUYN01000006_gene734	2.55e-280	783.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
k59_1595042_3	504487.JCM19302_340	4.79e-39	140.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1HY6A@117743|Flavobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1764342_1	296591.Bpro_1887	1.31e-33	127.0	COG1216@1|root,COG1216@2|Bacteria,1MYU7@1224|Proteobacteria,2VMRZ@28216|Betaproteobacteria,4AJWA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1764342_2	153948.NAL212_1316	4.19e-14	72.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,373QB@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_1537290_1	1348657.M622_07150	5.25e-109	332.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,2KVZR@206389|Rhodocyclales	206389|Rhodocyclales	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_351097_1	1406840.Q763_09755	1.55e-255	702.0	28IE2@1|root,2Z8G6@2|Bacteria,4NFI5@976|Bacteroidetes,1HZEW@117743|Flavobacteriia,2NSQG@237|Flavobacterium	976|Bacteroidetes	S	Conjugal transfer protein TraJ	-	-	-	-	-	-	-	-	-	-	-	-	CtnDOT_TraJ
k59_351097_2	1406840.Q763_09760	2.16e-123	353.0	COG3701@1|root,COG3701@2|Bacteria,4NFVT@976|Bacteroidetes,1I054@117743|Flavobacteriia,2NTNB@237|Flavobacterium	976|Bacteroidetes	U	Conjugal transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	VirB8
k59_971360_1	9371.XP_004715673.1	3.67e-29	126.0	COG3119@1|root,KOG3867@2759|Eukaryota,38CRA@33154|Opisthokonta,3BGPB@33208|Metazoa,3CTVU@33213|Bilateria,48564@7711|Chordata,48XC5@7742|Vertebrata,3JEM7@40674|Mammalia,34VFQ@311790|Afrotheria	33208|Metazoa	P	Iduronate	IDS	GO:0000323,GO:0003674,GO:0003824,GO:0004423,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005775,GO:0006022,GO:0006026,GO:0006027,GO:0006029,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008484,GO:0009056,GO:0009057,GO:0009100,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030203,GO:0030204,GO:0030207,GO:0031974,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0050654,GO:0070013,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903510	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
k59_577954_1	1137281.D778_02561	1.25e-37	140.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_577954_2	1406840.Q763_02390	4.07e-97	293.0	COG0730@1|root,COG0730@2|Bacteria,4NGP8@976|Bacteroidetes,1HXW1@117743|Flavobacteriia,2NS8E@237|Flavobacterium	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_577954_3	1347342.BN863_4640	5.79e-100	294.0	COG1584@1|root,COG1584@2|Bacteria,4NS18@976|Bacteroidetes,1I8V0@117743|Flavobacteriia	976|Bacteroidetes	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k59_577954_4	1484460.JSWG01000001_gene2381	7.45e-80	243.0	COG0739@1|root,COG0739@2|Bacteria,4NN4Q@976|Bacteroidetes,1I1CW@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_916339_1	411154.GFO_3240	2.24e-91	271.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1HY5F@117743|Flavobacteriia	976|Bacteroidetes	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_916339_2	1121931.AUHG01000010_gene226	1.3e-57	183.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1HWRK@117743|Flavobacteriia	976|Bacteroidetes	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_634556_1	1380600.AUYN01000009_gene1873	2.94e-112	335.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1HXRM@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_125530_2	362418.IW19_19570	8.01e-21	91.7	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2NSA1@237|Flavobacterium	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1141856_1	1123514.KB905901_gene41	5.77e-111	337.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,4608V@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1141856_2	1121097.JCM15093_1064	1.51e-06	49.3	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,2FNW8@200643|Bacteroidia,4AP79@815|Bacteroidaceae	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1707692_1	1380384.JADN01000007_gene1517	3.29e-70	226.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1HXNC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_1367581_1	354242.CJJ81176_0471	0.000479	50.1	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2YN51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k59_408382_1	1380600.AUYN01000009_gene1933	1.02e-145	440.0	COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_1481622_2	323850.Shew_1444	6.5e-136	396.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,2Q9UF@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	dctM	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_295399_1	504487.JCM19302_2848	0.0	1027.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1HXPG@117743|Flavobacteriia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_634600_1	1357275.AVEL02000080_gene1712	8.13e-22	98.2	COG1484@1|root,COG1484@2|Bacteria,1MZNW@1224|Proteobacteria,1RQFW@1236|Gammaproteobacteria,1ZA79@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	L	IstB-like ATP binding protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
k59_1481639_1	411154.GFO_2718	7.03e-89	266.0	COG1028@1|root,COG1028@2|Bacteria,4NKY7@976|Bacteroidetes,1HYA3@117743|Flavobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.206	ko:K08081	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R02832	RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_634610_1	62928.azo3645	1.48e-80	242.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,2KWHZ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_634610_2	1348657.M622_00025	1.29e-21	94.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KURZ@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_465334_1	216432.CA2559_06815	5.63e-72	231.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_634615_1	1392490.JHZX01000001_gene1917	4.23e-67	214.0	28J46@1|root,2Z906@2|Bacteria,4NFYM@976|Bacteroidetes,1HX14@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_1595154_1	572480.Arnit_0586	1.13e-84	256.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,42NMJ@68525|delta/epsilon subdivisions,2YMIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin-type protein, NapH MauN family	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_6
k59_125592_1	1137281.D778_02073	4.97e-133	407.0	COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,4PKRK@976|Bacteroidetes,1IJDQ@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_916399_1	1353276.JADR01000005_gene2396	2.69e-64	197.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1I4DC@117743|Flavobacteriia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_916399_2	1178825.ALIH01000010_gene394	1.05e-98	291.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I20T@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
k59_916399_3	1380600.AUYN01000009_gene1708	5e-161	460.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1HX12@117743|Flavobacteriia	976|Bacteroidetes	EGP	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k59_634626_1	945713.IALB_1659	7.8e-53	173.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
k59_1255161_1	90814.KL370891_gene1705	1.81e-17	76.6	COG2888@1|root,COG2888@2|Bacteria,1N3WA@1224|Proteobacteria	1224|Proteobacteria	J	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
k59_1255161_2	1168067.JAGP01000001_gene1510	1.19e-56	181.0	2ESN2@1|root,33K6N@2|Bacteria,1P1DC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1255161_3	1123514.KB905901_gene96	1.77e-166	480.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,45ZMQ@72273|Thiotrichales	72273|Thiotrichales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_1141924_1	929558.SMGD1_2093	1.95e-48	157.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2YP7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_12411_1	317025.Tcr_0389	1.75e-186	524.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1707771_1	1538644.KO02_03860	6.21e-38	136.0	2DCR5@1|root,32U02@2|Bacteria,4NTKM@976|Bacteroidetes,1IUPP@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1707771_2	1121931.AUHG01000016_gene1022	8.34e-13	67.4	COG5607@1|root,COG5607@2|Bacteria,4P4CQ@976|Bacteroidetes	976|Bacteroidetes	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
k59_1707788_1	745718.JADT01000028_gene2547	7.62e-30	119.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_1707788_2	1296415.JACC01000046_gene723	3.49e-18	83.6	COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1HY7J@117743|Flavobacteriia,2YHT9@290174|Aquimarina	976|Bacteroidetes	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_804131_1	1123248.KB893348_gene322	1.28e-46	162.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes	976|Bacteroidetes	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
k59_1367652_1	411154.GFO_3289	2.69e-143	416.0	COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,1HXTW@117743|Flavobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_1195521_1	563040.Saut_1790	1.61e-61	193.0	2ARMJ@1|root,31GY7@2|Bacteria,1QEMQ@1224|Proteobacteria,42VV2@68525|delta/epsilon subdivisions,2YQ9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_691681_1	1380600.AUYN01000001_gene2534	1.43e-112	345.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_1085272_1	1178825.ALIH01000003_gene2125	7.83e-149	424.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_239511_1	1121912.AUHD01000001_gene2430	1.18e-27	102.0	COG3592@1|root,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,1I5IR@117743|Flavobacteriia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
k59_239511_2	391603.FBALC1_05002	1.28e-63	196.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
k59_1141974_1	1168067.JAGP01000001_gene1255	8.59e-42	149.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,4605B@72273|Thiotrichales	72273|Thiotrichales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1141974_2	90814.KL370891_gene494	3.1e-32	121.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,45ZWD@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_351258_1	1178825.ALIH01000001_gene2347	1.44e-46	151.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1I1YY@117743|Flavobacteriia	976|Bacteroidetes	FG	HIT family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_351258_2	1380600.AUYN01000006_gene579	6.49e-66	203.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_971464_1	1484460.JSWG01000004_gene2630	9.85e-30	118.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_971464_2	504487.JCM19302_3694	4.1e-107	310.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
k59_971464_3	1347342.BN863_2250	4.36e-87	261.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1HYBP@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1085288_1	411154.GFO_3481	5.68e-63	197.0	COG0492@1|root,COG0492@2|Bacteria,4NHKD@976|Bacteroidetes,1I1D6@117743|Flavobacteriia	976|Bacteroidetes	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_804170_1	1380600.AUYN01000001_gene2443	1.05e-167	479.0	COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,1IJMK@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
k59_183081_2	1121875.KB907548_gene1529	2.26e-06	48.9	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1I0HE@117743|Flavobacteriia	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_691716_1	326298.Suden_0088	6.6e-54	189.0	COG2887@1|root,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_125667_1	1380600.AUYN01000009_gene1690	2.42e-106	323.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_804172_1	945713.IALB_2912	1.61e-49	164.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	MA20_17715	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
k59_1424826_1	1380600.AUYN01000009_gene1566	4.27e-95	281.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1141986_1	314265.R2601_20556	1.37e-12	68.9	COG1493@1|root,COG1493@2|Bacteria,1R0JS@1224|Proteobacteria,2U4BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1141986_2	90814.KL370891_gene1746	1.62e-115	338.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,460N1@72273|Thiotrichales	72273|Thiotrichales	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_183092_1	1123514.KB905899_gene1591	3.87e-83	260.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,46005@72273|Thiotrichales	72273|Thiotrichales	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_183092_2	1123518.ARWI01000001_gene795	1.71e-134	387.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,1S31N@1236|Gammaproteobacteria,460FD@72273|Thiotrichales	72273|Thiotrichales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_183092_3	1123518.ARWI01000001_gene794	1.5e-86	266.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,45ZZV@72273|Thiotrichales	72273|Thiotrichales	P	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_1142003_1	945713.IALB_2991	2.7e-36	129.0	COG1127@1|root,COG1127@2|Bacteria	2|Bacteria	Q	ATPase activity	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_1142003_2	1123388.AQWU01000074_gene1284	3.38e-13	68.6	COG1404@1|root,COG1404@2|Bacteria,1WJ4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
k59_1481778_1	572480.Arnit_2659	2.28e-101	305.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2YMNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1085323_1	326298.Suden_0533	2.73e-67	208.0	COG1846@1|root,COG1846@2|Bacteria,1PC0Y@1224|Proteobacteria,42WMV@68525|delta/epsilon subdivisions,2YQH5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_747064_1	504487.JCM19302_486	2.38e-119	351.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_804196_2	1123514.KB905900_gene2120	6.86e-20	89.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,45ZRD@72273|Thiotrichales	72273|Thiotrichales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k59_465451_1	709032.Sulku_2257	1.44e-07	60.8	COG0642@1|root,COG2205@2|Bacteria,1Q179@1224|Proteobacteria,4313A@68525|delta/epsilon subdivisions,2YS9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
k59_860051_1	509191.AEDB02000059_gene404	1.33e-18	89.4	COG0823@1|root,COG0823@2|Bacteria,1UYX2@1239|Firmicutes,24FDN@186801|Clostridia,3WK4T@541000|Ruminococcaceae	186801|Clostridia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1764567_1	572480.Arnit_2290	9.08e-115	345.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42PUI@68525|delta/epsilon subdivisions,2YN3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_1029869_1	1178825.ALIH01000001_gene2419	2.2e-228	671.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_1029869_2	1121875.KB907546_gene2678	1.27e-33	130.0	2DRZU@1|root,33DVD@2|Bacteria,4P3PD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747076_2	1298593.TOL_3682	1.61e-34	127.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1RNV8@1236|Gammaproteobacteria,1XIQP@135619|Oceanospirillales	135619|Oceanospirillales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_972580_1	572480.Arnit_1537	8e-59	189.0	COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,42YUG@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
k59_1539007_1	1232410.KI421424_gene1737	4.41e-12	67.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43S9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	DALR_2	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_861766_1	1123514.KB905903_gene390	6.41e-82	258.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,460P1@72273|Thiotrichales	72273|Thiotrichales	FP	Belongs to the GppA Ppx family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_693440_1	1343739.PAP_08585	1.72e-30	118.0	COG4902@1|root,arCOG03957@2157|Archaea,2XX05@28890|Euryarchaeota,243QP@183968|Thermococci	183968|Thermococci	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k59_693451_1	572480.Arnit_0034	1.47e-159	452.0	COG0667@1|root,COG0667@2|Bacteria,1RK6Z@1224|Proteobacteria,43BI8@68525|delta/epsilon subdivisions,2YT8P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_410187_1	1442598.JABW01000030_gene1382	2.69e-116	344.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_410187_2	1442598.JABW01000030_gene1383	5.78e-61	202.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2YTG8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k59_127343_1	1172190.M947_01110	2.63e-108	324.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1086909_1	400668.Mmwyl1_0905	1.3e-85	265.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria,1XK9Z@135619|Oceanospirillales	135619|Oceanospirillales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_1597000_1	391603.FBALC1_13102	2.35e-38	133.0	COG0668@1|root,COG0668@2|Bacteria,4NP36@976|Bacteroidetes,1I1XC@117743|Flavobacteriia	976|Bacteroidetes	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1597000_2	143224.JQMD01000002_gene3945	1.73e-20	90.5	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1HY56@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_1143559_2	69328.PVLB_27102	2.48e-26	102.0	2BW73@1|root,2ZHHX@2|Bacteria,1P6PK@1224|Proteobacteria,1SVI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_918040_1	1172190.M947_01200	7.01e-86	272.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1653130_1	748247.AZKH_p0116	2.62e-50	163.0	COG3631@1|root,COG3631@2|Bacteria,1PT2G@1224|Proteobacteria,2WA86@28216|Betaproteobacteria,2KYWR@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_636470_1	675816.VIA_002785	1.82e-05	53.5	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,1SGZF@1236|Gammaproteobacteria,1XYAZ@135623|Vibrionales	135623|Vibrionales	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
k59_1426479_1	1150621.SMUL_2613	2.65e-42	145.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,42N20@68525|delta/epsilon subdivisions,2YN0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_1426479_2	1172190.M947_00640	2.02e-29	115.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_410216_1	1190606.AJYG01000173_gene579	2.35e-20	88.2	COG2207@1|root,COG2207@2|Bacteria,1NDY5@1224|Proteobacteria,1T39M@1236|Gammaproteobacteria,1Y34N@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_410216_2	1288826.MSNKSG1_14172	9.38e-16	75.9	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,464HZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1653146_1	1380600.AUYN01000009_gene1280	2.25e-55	175.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1I17M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_1653146_2	1123037.AUDE01000009_gene1365	1.54e-25	95.5	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1I55H@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_1653146_3	504487.JCM19302_3166	1.06e-110	319.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1HXH9@117743|Flavobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_71700_1	411154.GFO_1792	2.44e-181	511.0	2CCVV@1|root,2Z7YU@2|Bacteria,4NDUA@976|Bacteroidetes,1HXAA@117743|Flavobacteriia	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_1143588_1	1380600.AUYN01000001_gene2685	2.7e-159	467.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1143588_2	1380600.AUYN01000001_gene2686	4.43e-93	272.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1I19U@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_861828_1	143224.JQMD01000002_gene426	3.76e-11	63.9	COG3637@1|root,COG3637@2|Bacteria,4PKKK@976|Bacteroidetes,1HYEJ@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
k59_861828_2	1408473.JHXO01000007_gene759	2.53e-99	292.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,2FTMR@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
k59_861828_3	1380600.AUYN01000001_gene2554	6.23e-95	281.0	COG1595@1|root,COG1595@2|Bacteria,4NMVF@976|Bacteroidetes,1I1G0@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	SatD
k59_861828_4	1380600.AUYN01000001_gene2555	3.04e-13	67.4	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,1HXKF@117743|Flavobacteriia	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
k59_467144_1	563040.Saut_1436	3.75e-103	313.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1539092_1	1178825.ALIH01000003_gene2216	6.75e-59	192.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1HWZ8@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1597062_1	929558.SMGD1_1573	6.56e-92	271.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1597062_2	326298.Suden_1894	3.23e-157	450.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_636519_1	983545.Glaag_0651	4.09e-37	131.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,466RV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	lipocalin	blc	GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
k59_636519_2	1286631.X805_14920	4.05e-19	85.9	COG2374@1|root,COG2374@2|Bacteria,1R5QF@1224|Proteobacteria,2VVIP@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_579880_1	1469557.JSWF01000028_gene2916	2.71e-68	214.0	COG0463@1|root,COG0463@2|Bacteria,4NK1T@976|Bacteroidetes,1HZ1Q@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_579880_2	1178825.ALIH01000009_gene1323	3.33e-48	166.0	COG1541@1|root,COG1541@2|Bacteria,4NFFT@976|Bacteroidetes,1HZKR@117743|Flavobacteriia	976|Bacteroidetes	H	COG1541 Coenzyme F390 synthetase	capK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_71729_1	929558.SMGD1_0565	1.35e-121	379.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1426534_1	1178825.ALIH01000003_gene2116	1.22e-177	498.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia	976|Bacteroidetes	EF	ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_1426534_2	504487.JCM19302_1900	4.38e-59	190.0	COG2353@1|root,COG2353@2|Bacteria,4NTB0@976|Bacteroidetes,1I43M@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1086996_1	1172190.M947_00125	3.61e-42	150.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2YNG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1086996_2	929558.SMGD1_2574	3.23e-29	109.0	COG1381@1|root,COG1381@2|Bacteria,1QAJR@1224|Proteobacteria,42NUJ@68525|delta/epsilon subdivisions,2YPCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RecO N terminal	-	-	-	-	-	-	-	-	-	-	-	-	RecO_N_2
k59_1483607_1	317025.Tcr_0378	8.17e-32	119.0	2BVEU@1|root,32QUD@2|Bacteria,1RJ4J@1224|Proteobacteria,1S5X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TnsA endonuclease N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Tn7_Tnp_TnsA_N
k59_1483607_2	90814.KL370891_gene320	3.02e-28	113.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,45ZU1@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1314827_1	1347342.BN863_20870	1.38e-91	293.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_1597095_1	326298.Suden_1244	2.28e-82	268.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_127443_1	616991.JPOO01000001_gene4608	1.83e-56	191.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia,23H4P@178469|Arenibacter	976|Bacteroidetes	P	STAS domain	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_127443_2	1380600.AUYN01000009_gene1155	7.57e-60	203.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1597105_1	1123037.AUDE01000021_gene2199	2.15e-69	231.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_918123_1	1123514.KB905899_gene1341	4.66e-77	235.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,462NU@72273|Thiotrichales	72273|Thiotrichales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_918123_2	1123518.ARWI01000001_gene421	5.86e-130	379.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,460WQ@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_184895_1	929558.SMGD1_2231	7.56e-240	664.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_1257037_1	985255.APHJ01000022_gene3211	1.77e-30	117.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia,2P5ET@244698|Gillisia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1257037_2	1137281.D778_01467	3.61e-70	214.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_1426579_1	411154.GFO_2289	1.52e-194	543.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1HX5R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_663517_1	1111730.ATTM01000002_gene1273	5.39e-33	130.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2NTMJ@237|Flavobacterium	976|Bacteroidetes	E	aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_1511166_1	1353528.DT23_15210	5.51e-156	444.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2XN12@285107|Thioclava	28211|Alphaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	MA20_36195	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
k59_1511166_2	1353528.DT23_15215	1.04e-08	54.7	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2TV1D@28211|Alphaproteobacteria,2XMU7@285107|Thioclava	28211|Alphaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_1113759_1	572480.Arnit_3050	1.53e-80	243.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2YMEM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_1113759_2	572480.Arnit_3051	1.81e-67	207.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_493669_1	411154.GFO_3467	2.63e-132	397.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_1283807_1	572480.Arnit_0474	1.34e-144	412.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_833436_1	411154.GFO_3216	1.79e-101	308.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1HXA7@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1623713_1	314264.ROS217_02160	3.43e-11	63.9	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,46NFD@74030|Roseovarius	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_1623713_2	1208323.B30_18997	8.92e-60	186.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2UBZM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
k59_327351_1	563040.Saut_1440	1.67e-69	222.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_835305_1	1532557.JL37_14200	8.03e-38	145.0	COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,2VNMU@28216|Betaproteobacteria,3T5D7@506|Alcaligenaceae	28216|Betaproteobacteria	L	polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k59_1625564_1	563040.Saut_1913	9.68e-16	75.5	2AIIS@1|root,3190V@2|Bacteria,1Q1CZ@1224|Proteobacteria,42TB4@68525|delta/epsilon subdivisions,2YPN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1625564_2	326298.Suden_1905	8e-106	315.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2YMMY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_382280_1	1178825.ALIH01000009_gene1347	4.92e-70	225.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,4NDVW@976|Bacteroidetes,1HXBF@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome C biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_382280_2	1137281.D778_01893	1.47e-205	572.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,1HYFQ@117743|Flavobacteriia	976|Bacteroidetes	JM	dTDP-glucose pyrophosphorylase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_382280_3	1506583.JQJY01000002_gene1855	3.93e-87	257.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia,2NVXP@237|Flavobacterium	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_382280_4	1046627.BZARG_1671	4.02e-89	275.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_607062_1	592029.DDD_0916	3.56e-16	79.0	COG0474@1|root,COG0474@2|Bacteria,4NHBI@976|Bacteroidetes,1HY51@117743|Flavobacteriia,3HJZ4@363408|Nonlabens	976|Bacteroidetes	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_607062_2	1121931.AUHG01000010_gene128	4.35e-158	453.0	COG1249@1|root,COG1249@2|Bacteria,4NFUB@976|Bacteroidetes,1HXVG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_269876_1	323850.Shew_2164	1.85e-200	569.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,2Q954@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N,AcylCoA_dehyd_C
k59_1218896_1	90814.KL370891_gene1263	2.75e-47	171.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,4603W@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1218896_2	90814.KL370891_gene1262	1.07e-36	132.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,460KX@72273|Thiotrichales	72273|Thiotrichales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k59_891019_1	1121931.AUHG01000010_gene440	3.2e-121	384.0	COG0823@1|root,COG4677@1|root,COG5276@1|root,COG0823@2|Bacteria,COG4677@2|Bacteria,COG5276@2|Bacteria,4PNFN@976|Bacteroidetes,1I0J5@117743|Flavobacteriia	976|Bacteroidetes	G	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,TSP_3
k59_1398528_1	525146.Ddes_2037	1.58e-90	271.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions,2WNY3@28221|Deltaproteobacteria,2M9RB@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_778094_1	504487.JCM19302_4010	7.89e-109	324.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1345630_1	1123518.ARWI01000001_gene219	1.69e-111	330.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,4607C@72273|Thiotrichales	72273|Thiotrichales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_42224_1	1511.CLOST_0232	2.4e-49	174.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1TQAZ@1239|Firmicutes,24H4D@186801|Clostridia	186801|Clostridia	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_439785_1	926559.JoomaDRAFT_2745	6.2e-25	103.0	COG0477@1|root,COG0477@2|Bacteria,4PKB1@976|Bacteroidetes,1HX4H@117743|Flavobacteriia	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_439785_2	388413.ALPR1_02425	6.97e-48	160.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,47JV0@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
k59_214663_1	981085.XP_010087481.1	7.11e-20	94.0	COG0318@1|root,KOG1176@2759|Eukaryota,37T8X@33090|Viridiplantae,3GG97@35493|Streptophyta,4JNDT@91835|fabids	35493|Streptophyta	I	4-coumarate-coa ligase	4CL3	GO:0003674,GO:0003824,GO:0006725,GO:0007275,GO:0008150,GO:0008152,GO:0009555,GO:0009653,GO:0009698,GO:0009987,GO:0010208,GO:0010584,GO:0010927,GO:0016043,GO:0016207,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019748,GO:0022607,GO:0030198,GO:0032501,GO:0032502,GO:0032989,GO:0043062,GO:0044085,GO:0044237,GO:0045229,GO:0048229,GO:0048646,GO:0048856,GO:0048869,GO:0071704,GO:0071840,GO:0085029,GO:1901360	6.2.1.12	ko:K01904	ko00130,ko00360,ko00940,ko01100,ko01110,map00130,map00360,map00940,map01100,map01110	M00039,M00137,M00350	R01616,R01943,R02194,R02221,R02255,R06583	RC00004,RC00131	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_944681_1	1121007.AUML01000040_gene3642	4.23e-78	256.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2YH52@290174|Aquimarina	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1455177_1	1121904.ARBP01000018_gene2661	8.51e-91	269.0	COG2249@1|root,COG2249@2|Bacteria,4NGBQ@976|Bacteroidetes,47UQ1@768503|Cytophagia	976|Bacteroidetes	S	Flavodoxin-like fold	mdaB	-	-	ko:K03923	-	-	-	-	ko00000	-	-	-	Flavodoxin_2
k59_1455177_2	319236.JCM19294_32	3.58e-13	67.8	COG0583@1|root,COG0583@2|Bacteria,4NG2V@976|Bacteroidetes,1HXUD@117743|Flavobacteriia	976|Bacteroidetes	K	LysR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_666691_1	1565129.JSFF01000019_gene1682	1.85e-125	364.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1PQPU@1224|Proteobacteria,1RYEZ@1236|Gammaproteobacteria,2Q9CC@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM response regulator receiver	cheV3	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1568418_1	323850.Shew_2421	2.74e-24	106.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QA47@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
k59_835373_2	880073.Calab_2023	9.31e-44	156.0	COG0493@1|root,COG0493@2|Bacteria,2NNRI@2323|unclassified Bacteria	2|Bacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.17.1.9,1.4.1.13,1.4.1.14	ko:K00123,ko:K00266	ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	-	R00093,R00114,R00248,R00519	RC00006,RC00010,RC02796,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_1739648_1	572477.Alvin_1248	9e-56	183.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,1RRAH@1236|Gammaproteobacteria,1WW2H@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM CRISPR-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
k59_607151_1	411154.GFO_3245	1.29e-163	462.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
k59_101903_1	1268240.ATFI01000004_gene4088	1.17e-12	70.5	COG1239@1|root,COG1239@2|Bacteria,4PMD7@976|Bacteroidetes,2FPR2@200643|Bacteroidia,4AT2I@815|Bacteroidaceae	976|Bacteroidetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1059455_1	1125863.JAFN01000001_gene1910	4.25e-21	97.4	COG3880@1|root,COG3880@2|Bacteria,1NT4T@1224|Proteobacteria,42Z7E@68525|delta/epsilon subdivisions,2WUQB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM UvrB UvrC protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
k59_778192_1	572480.Arnit_0788	1.44e-18	81.3	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42QYK@68525|delta/epsilon subdivisions,2YNZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ABC transporter, ATP-binding protein	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k59_778192_2	572480.Arnit_0787	2.73e-47	152.0	COG2863@1|root,COG2863@2|Bacteria,1Q9CC@1224|Proteobacteria,43118@68525|delta/epsilon subdivisions,2YS5W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_891121_1	326298.Suden_1364	7.96e-139	396.0	COG1136@1|root,COG1136@2|Bacteria,1MXVW@1224|Proteobacteria,42MKV@68525|delta/epsilon subdivisions,2YMUC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_891121_2	1499683.CCFF01000017_gene1620	5.22e-23	96.7	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,36FD6@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_101927_1	435908.IDSA_05595	6.49e-118	360.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,2QEZX@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_101927_2	1123228.AUIH01000004_gene1015	8.94e-39	131.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM98@135619|Oceanospirillales	135619|Oceanospirillales	K	Cold-shock'	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1739697_1	367737.Abu_0102	3.23e-26	109.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YR8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,dCache_2
k59_1739697_2	563040.Saut_0637	6.6e-16	78.6	COG2199@1|root,COG4753@1|root,COG3706@2|Bacteria,COG4753@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2YN86@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1345726_1	1265503.KB905160_gene2733	6.58e-28	117.0	COG2931@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,1PIDH@1224|Proteobacteria,1SXX5@1236|Gammaproteobacteria,2Q7Y4@267889|Colwelliaceae	1236|Gammaproteobacteria	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k59_327519_1	1121931.AUHG01000012_gene2551	1.31e-170	486.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_382444_1	317025.Tcr_0035	1.57e-168	486.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,460EF@72273|Thiotrichales	72273|Thiotrichales	T	GAF domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_1514330_1	326298.Suden_1844	2.2e-66	209.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1514330_2	929558.SMGD1_2066	1.8e-42	154.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1683032_2	1537917.JU82_01300	5.14e-72	218.0	COG2033@1|root,COG2033@2|Bacteria,1NDWH@1224|Proteobacteria,42RSM@68525|delta/epsilon subdivisions,2YP5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
k59_551078_1	929558.SMGD1_0594	1.55e-26	105.0	COG3391@1|root,COG3391@2|Bacteria,1QUIK@1224|Proteobacteria,42RTQ@68525|delta/epsilon subdivisions,2YPA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	amine dehydrogenase activity	napL	-	-	-	-	-	-	-	-	-	-	-	-
k59_551078_2	326298.Suden_1520	1.66e-72	221.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,430A1@68525|delta/epsilon subdivisions,2YSXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS domain	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_382453_2	929558.SMGD1_1717	9.6e-40	137.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_607202_1	1123518.ARWI01000001_gene2010	2.28e-148	426.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria,460DB@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM lipopolysaccharide heptosyltransferase I	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_607202_2	317025.Tcr_1517	1.84e-29	114.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,4606W@72273|Thiotrichales	72273|Thiotrichales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_1173670_1	377629.TERTU_2818	7.8e-25	99.4	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1S6CV@1236|Gammaproteobacteria,2PPY2@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Tryptophan synthase alpha chain	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_1173670_2	1121935.AQXX01000082_gene155	4.11e-53	179.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RNVE@1236|Gammaproteobacteria,1XIEQ@135619|Oceanospirillales	135619|Oceanospirillales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_551092_1	1191523.MROS_1841	6.1e-17	85.5	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529,ko:K19171	-	-	-	-	ko00000,ko02048,ko03036	-	-	-	SMC_N,SMC_hinge
k59_1173674_1	1296416.JACB01000006_gene273	3.44e-122	358.0	2DBKE@1|root,2Z9SW@2|Bacteria,4NRWN@976|Bacteroidetes,1I012@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
k59_1173674_2	1296416.JACB01000006_gene272	4.74e-32	121.0	COG0296@1|root,COG0296@2|Bacteria,4NJ7Z@976|Bacteroidetes,1HZ6E@117743|Flavobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
k59_1345768_1	563040.Saut_0657	1.14e-100	307.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1219083_1	1172190.M947_02675	8.05e-201	572.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2YMJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
k59_270054_1	572480.Arnit_2362	1.44e-112	326.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2YMPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_270054_2	572480.Arnit_2361	2.73e-29	107.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2YP9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_607241_1	391603.FBALC1_09982	8.73e-86	260.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1I1DS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k59_42372_1	411154.GFO_3470	2.07e-167	482.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
k59_891201_1	411154.GFO_1523	2.71e-39	135.0	COG1238@1|root,COG1238@2|Bacteria,4NMW6@976|Bacteroidetes,1HZCA@117743|Flavobacteriia	976|Bacteroidetes	I	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_891201_2	1121931.AUHG01000012_gene2643	6.41e-68	208.0	2DMCX@1|root,32UGQ@2|Bacteria,4NT6Y@976|Bacteroidetes,1I48A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_382517_1	1172190.M947_08975	3.39e-158	453.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_666848_1	1123054.KB907724_gene2807	3.74e-183	530.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1WWMA@135613|Chromatiales	135613|Chromatiales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_607260_2	411154.GFO_2832	1.84e-94	275.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1I16U@117743|Flavobacteriia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_607260_3	411154.GFO_2831	8.92e-33	114.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,1I53X@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_496914_1	90814.KL370891_gene505	1.1e-90	272.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,45ZN2@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_1796889_1	62928.azo0165	3.78e-123	363.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,2KVEJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS_8
k59_1345845_1	339670.Bamb_1842	2.97e-72	230.0	COG3392@1|root,COG3392@2|Bacteria,1PRRN@1224|Proteobacteria,2W5K4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	D12 class N6 adenine-specific DNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MethyltransfD12
k59_327635_1	1392488.JHZY01000004_gene1758	0.000249	41.6	2F5QJ@1|root,33Y9E@2|Bacteria,4P2Z5@976|Bacteroidetes,1I9BH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_327635_2	1392488.JHZY01000004_gene1757	1.26e-66	211.0	2DQEE@1|root,336AX@2|Bacteria,4P398@976|Bacteroidetes,1I9AR@117743|Flavobacteriia	976|Bacteroidetes	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
k59_214855_2	1416759.AYMR01000032_gene1974	7.49e-53	181.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4FNMX@85023|Microbacteriaceae	201174|Actinobacteria	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_835492_1	391603.FBALC1_08518	9.09e-96	306.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
k59_1417537_1	411154.GFO_3219	3.94e-110	328.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HWYG@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_62044_1	1137281.D778_00618	3.1e-121	348.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1HXSB@117743|Flavobacteriia	976|Bacteroidetes	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
k59_62044_2	1178825.ALIH01000001_gene2699	5.9e-30	108.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1I5AD@117743|Flavobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
k59_683673_1	1454004.AW11_03955	2.61e-45	154.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK32@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_683673_2	1528106.JRJE01000020_gene2314	7.83e-09	53.1	COG5470@1|root,COG5470@2|Bacteria,1N54U@1224|Proteobacteria,2UEV2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
k59_1587291_1	1123518.ARWI01000001_gene1731	1.49e-135	421.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1134909_2	929558.SMGD1_2278	7.86e-65	204.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2YNYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_626895_1	945713.IALB_2085	8.84e-42	151.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
k59_287909_1	1123518.ARWI01000001_gene2245	8.46e-93	282.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_287909_2	90814.KL370891_gene1418	3.18e-57	178.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,4618R@72273|Thiotrichales	72273|Thiotrichales	J	RNA-binding protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
k59_287909_3	1123518.ARWI01000001_gene2247	1.33e-74	227.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,460FZ@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_1643788_1	929558.SMGD1_1427	1.06e-63	201.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2YMG8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
k59_1643788_2	572480.Arnit_2439	3.48e-27	110.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43AU6@68525|delta/epsilon subdivisions,2YRCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	PT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1
k59_570261_1	225849.swp_3633	6.03e-134	407.0	COG0247@1|root,COG0277@1|root,COG1150@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1150@2|Bacteria,1MU6Y@1224|Proteobacteria,1RM7Z@1236|Gammaproteobacteria,2QAKZ@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	lldE	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
k59_175189_1	316275.VSAL_I1222	8.26e-47	171.0	COG0729@1|root,COG0729@2|Bacteria,1QVQI@1224|Proteobacteria,1T2H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1700058_1	717772.THIAE_07755	1.31e-14	72.8	COG0810@1|root,COG5373@1|root,COG0810@2|Bacteria,COG5373@2|Bacteria,1MZXC@1224|Proteobacteria,1S4GB@1236|Gammaproteobacteria,46166@72273|Thiotrichales	72273|Thiotrichales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1700058_2	1123518.ARWI01000001_gene724	1.6e-84	251.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S852@1236|Gammaproteobacteria,463R2@72273|Thiotrichales	72273|Thiotrichales	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_1134920_1	62928.azo2382	3.77e-44	151.0	28KDQ@1|root,2ZA05@2|Bacteria,1QVCG@1224|Proteobacteria,2VTD9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1134920_2	1168067.JAGP01000001_gene1766	1.37e-20	87.4	COG4659@1|root,COG4659@2|Bacteria,1RFGW@1224|Proteobacteria,1S603@1236|Gammaproteobacteria,462YS@72273|Thiotrichales	72273|Thiotrichales	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k59_1587316_1	1122621.ATZA01000074_gene1835	1.57e-46	165.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPQC@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M24B, X-Pro dipeptidase aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_457655_1	90814.KL370891_gene263	5.4e-276	779.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_5302_1	1121931.AUHG01000010_gene775	1.31e-171	484.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1HXVZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_175219_1	62928.azo1668	2.22e-19	84.7	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,2KUQT@206389|Rhodocyclales	206389|Rhodocyclales	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	DUF4072,HAD
k59_5309_1	745718.JADT01000011_gene851	2.22e-95	291.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1HXAF@117743|Flavobacteriia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1643838_1	1121859.KB890750_gene505	5.13e-53	178.0	COG0726@1|root,COG0726@2|Bacteria,4NM1N@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1643838_2	483216.BACEGG_02825	0.00014	44.7	COG0438@1|root,COG0438@2|Bacteria,4NMHX@976|Bacteroidetes,2FTHY@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_796467_1	945713.IALB_2179	1.46e-95	293.0	COG0459@1|root,COG0459@2|Bacteria	2|Bacteria	O	protein refolding	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1078011_1	1336233.JAEH01000056_gene1966	1.24e-32	123.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,1RP5F@1236|Gammaproteobacteria,2QA2A@267890|Shewanellaceae	1236|Gammaproteobacteria	E	peptidase dimerisation domain protein	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
k59_739767_1	1178825.ALIH01000005_gene340	5.8e-94	286.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_570327_1	1122225.AULQ01000012_gene464	1.44e-77	232.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
k59_5325_1	1121931.AUHG01000010_gene430	9.98e-116	345.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HYK4@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_401076_1	1173027.Mic7113_1030	2.34e-60	209.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,HATPase_c,HisKA,Pkinase
k59_683758_1	655815.ZPR_4324	4.03e-76	246.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1HZ06@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k59_343944_1	1046627.BZARG_2625	8.86e-137	392.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_343944_2	1178825.ALIH01000019_gene1243	2.27e-130	374.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_1360463_1	1537917.JU82_02480	5.26e-75	251.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,1R74K@1224|Proteobacteria,42Q92@68525|delta/epsilon subdivisions,2YN5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	restriction	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
k59_457712_1	411154.GFO_0767	3.37e-95	283.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia	976|Bacteroidetes	E	Shikimate	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
k59_457712_2	411154.GFO_0768	1.13e-19	86.3	COG2035@1|root,COG2035@2|Bacteria,4NDU1@976|Bacteroidetes,1HYB3@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF368
k59_1417632_1	1121931.AUHG01000012_gene2513	1.95e-67	211.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1HXDQ@117743|Flavobacteriia	976|Bacteroidetes	S	Lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k59_1417632_2	1121931.AUHG01000012_gene2514	5.72e-53	169.0	COG4706@1|root,COG4706@2|Bacteria,4NSB5@976|Bacteroidetes,1IJF7@117743|Flavobacteriia	976|Bacteroidetes	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175274_1	411154.GFO_0426	4.77e-10	58.9	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_175274_2	1121931.AUHG01000015_gene1171	1.36e-116	341.0	298D5@1|root,2ZVIG@2|Bacteria,4NP2F@976|Bacteroidetes,1I24E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
k59_175274_3	411154.GFO_0428	4.57e-40	139.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
k59_739806_1	1172190.M947_09680	4.16e-79	241.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2YP1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_1135001_1	1172190.M947_10250	2.84e-77	251.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_1022535_1	1123037.AUDE01000009_gene1295	1.02e-05	46.6	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1HXFU@117743|Flavobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1022535_2	745718.JADT01000008_gene3076	1.75e-167	482.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_1022546_1	1298593.TOL_0094	1.45e-36	141.0	COG0642@1|root,COG0784@1|root,COG3447@1|root,COG3614@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_8,Response_reg
k59_62198_1	1250278.JQNQ01000001_gene1472	4.82e-43	149.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k59_62198_2	1121931.AUHG01000010_gene858	1.38e-159	469.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_401139_1	1123037.AUDE01000019_gene3306	3.34e-79	242.0	2ATWF@1|root,31JFP@2|Bacteria,4NQ9K@976|Bacteroidetes,1I3SN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_401139_2	1336803.PHEL49_0906	4.74e-165	470.0	COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,1HZJN@117743|Flavobacteriia,3VVWK@52959|Polaribacter	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_967224_1	1442598.JABW01000030_gene1355	2.71e-35	138.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1MUB8@1224|Proteobacteria,42ZE8@68525|delta/epsilon subdivisions,2YRGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS,PAS_3,dCache_3
k59_853843_1	1380600.AUYN01000007_gene3205	2.35e-92	286.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1249270_1	1353528.DT23_07750	3.71e-115	337.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2XKHM@285107|Thioclava	28211|Alphaproteobacteria	GM	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_572021_1	411154.GFO_2653	4.85e-212	601.0	COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,4NFQX@976|Bacteroidetes,1HWVN@117743|Flavobacteriia	976|Bacteroidetes	P	serves to protect cells from the toxic effects of hydrogen peroxide	katE	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel,DJ-1_PfpI
k59_1024172_1	688270.Celal_0462	6.94e-41	141.0	COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,4NE29@976|Bacteroidetes,1HZ34@117743|Flavobacteriia,1FAB1@104264|Cellulophaga	976|Bacteroidetes	F	COG1051 ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_1024172_2	1392490.JHZX01000001_gene1958	8.08e-18	81.3	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1191460_1	1178825.ALIH01000010_gene475	1.53e-72	218.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_1191460_2	555500.I215_14119	3.44e-31	110.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_1191460_3	1392490.JHZX01000001_gene426	2.47e-97	285.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_1136471_2	1406840.Q763_09650	5.69e-80	238.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,1IJEF@117743|Flavobacteriia	976|Bacteroidetes	K	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
k59_1136471_3	1406840.Q763_09645	3.3e-129	366.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia,2NTF8@237|Flavobacterium	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_1136471_4	1406840.Q763_09640	6.16e-260	711.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia,2NTB0@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1136471_5	1406840.Q763_09635	2.15e-107	309.0	COG0454@1|root,COG0456@2|Bacteria,4NHRI@976|Bacteroidetes,1I38S@117743|Flavobacteriia,2NVVX@237|Flavobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1136471_6	649349.Lbys_1079	4.82e-84	251.0	COG0454@1|root,COG0456@2|Bacteria,4NNJA@976|Bacteroidetes,47YE6@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1136471_7	1406840.Q763_09625	5.08e-160	452.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1HWKK@117743|Flavobacteriia,2P065@237|Flavobacterium	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1531812_1	1122207.MUS1_09525	1.82e-94	288.0	28J49@1|root,2Z909@2|Bacteria,1MXMR@1224|Proteobacteria,1RREI@1236|Gammaproteobacteria,1XJCA@135619|Oceanospirillales	135619|Oceanospirillales	S	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1079614_1	1337936.IJ00_13950	2.82e-78	272.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_1306854_1	1380600.AUYN01000006_gene331	1.27e-238	674.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
k59_515146_1	90813.JQMT01000001_gene1801	8.71e-97	288.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales	72273|Thiotrichales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_515146_2	90813.JQMT01000001_gene1802	6.92e-21	86.3	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,460UN@72273|Thiotrichales	72273|Thiotrichales	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_233463_1	90814.KL370891_gene1602	3.63e-107	318.0	COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1306878_1	985255.APHJ01000022_gene3192	2.72e-26	108.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2P7C2@244698|Gillisia	976|Bacteroidetes	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
k59_1758527_1	1565129.JSFF01000029_gene3030	6.71e-124	365.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,2QAK1@267890|Shewanellaceae	1236|Gammaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103	IlvC,IlvN
k59_402757_1	1168067.JAGP01000001_gene1929	1.69e-91	279.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_1191482_1	225849.swp_2004	1.4e-133	414.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,2QAG1@267890|Shewanellaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1191482_2	1236541.BALL01000072_gene4876	7.02e-07	49.7	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,2Q9YQ@267890|Shewanellaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_345582_1	709032.Sulku_1630	2.63e-63	208.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,ABC_sub_bind,CHASE4,HATPase_c,HisKA,PAS_4,PAS_9,dCache_1
k59_1589169_1	1250005.PHEL85_2280	5.34e-135	394.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HZ86@117743|Flavobacteriia,3VX1M@52959|Polaribacter	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_402766_1	991.IW20_11470	1.77e-13	77.8	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2NUPY@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter substrate-binding protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1249332_1	483215.BACFIN_06316	4.79e-52	186.0	COG0521@1|root,COG0521@2|Bacteria,4NEQZ@976|Bacteroidetes,2FP3V@200643|Bacteroidia,4AP9X@815|Bacteroidaceae	976|Bacteroidetes	H	Susd and RagB outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_1362050_2	1407650.BAUB01000019_gene2502	1.32e-35	134.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1GYG1@1129|Synechococcus	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_120051_1	1347342.BN863_4800	1.19e-87	263.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1HY9B@117743|Flavobacteriia	976|Bacteroidetes	J	rna methyltransferase	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_120051_2	1034807.FBFL15_0360	3.64e-15	72.4	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1HXZH@117743|Flavobacteriia,2NS8J@237|Flavobacterium	976|Bacteroidetes	S	PorT protein	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1362052_1	367737.Abu_2289	2.58e-52	169.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1546228_2	292415.Tbd_0863	4.26e-23	101.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,1KRCU@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_304884_1	1121931.AUHG01000010_gene357	4.48e-91	278.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_304884_2	411154.GFO_3370	1.44e-62	194.0	COG0454@1|root,COG0456@2|Bacteria,4NPA8@976|Bacteroidetes,1I18M@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_248911_1	90814.KL370891_gene1313	1.32e-128	399.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,45ZSY@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1094212_1	1172190.M947_09465	2.35e-54	175.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,42RSP@68525|delta/epsilon subdivisions,2YPDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_1094212_2	1150621.SMUL_2191	3.29e-40	143.0	COG3658@1|root,COG3658@2|Bacteria,1REFV@1224|Proteobacteria,42Q0G@68525|delta/epsilon subdivisions,2YN98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
k59_701397_1	1123518.ARWI01000001_gene351	2.24e-137	397.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4606S@72273|Thiotrichales	72273|Thiotrichales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_21056_1	411154.GFO_2773	8.83e-134	397.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1HXSX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_925156_1	572480.Arnit_1972	7.75e-44	162.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.117,4.2.1.3	ko:K01681,ko:K20455	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900,R11263	RC00497,RC00498,RC00618,RC01152	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_869435_1	1469557.JSWF01000014_gene2564	1.89e-94	283.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1HX2G@117743|Flavobacteriia	976|Bacteroidetes	S	O-Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
k59_248932_1	1120968.AUBX01000009_gene570	2.22e-85	273.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47JEZ@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
k59_1491304_1	497321.C664_15713	6.69e-21	92.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,dCache_1
k59_1491304_2	497321.C664_02620	2.2e-37	136.0	COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2VMTR@28216|Betaproteobacteria,2KY0M@206389|Rhodocyclales	206389|Rhodocyclales	M	COG2951 Membrane-bound lytic murein transglycosylase B	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SLT_2
k59_814004_2	1107311.Q767_13925	8.57e-11	64.3	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia,2NTAI@237|Flavobacterium	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_978265_1	34007.IT40_23565	2.93e-50	173.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,2PY5N@265|Paracoccus	28211|Alphaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	MA20_27250	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_643985_1	760154.Sulba_0399	6.06e-47	166.0	COG4773@1|root,COG4773@2|Bacteria,1R8BS@1224|Proteobacteria,42M7T@68525|delta/epsilon subdivisions,2YS9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM outer membrane porin	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1546292_1	1121931.AUHG01000010_gene457	3.42e-29	113.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,1HZCS@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
k59_1546292_2	1121931.AUHG01000010_gene458	1.3e-53	182.0	COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,1HZNM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_1202440_2	929558.SMGD1_1981	1.08e-120	350.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2YR7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k59_1660803_1	1178825.ALIH01000007_gene1586	6.92e-96	281.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_1660803_2	1380600.AUYN01000009_gene965	8.91e-231	657.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1HXS7@117743|Flavobacteriia	976|Bacteroidetes	C	Malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_869487_1	1250005.PHEL85_0822	1.61e-288	831.0	COG3866@1|root,COG5498@1|root,COG3866@2|Bacteria,COG5498@2|Bacteria,4NJUD@976|Bacteroidetes,1IG6T@117743|Flavobacteriia,3VW2U@52959|Polaribacter	976|Bacteroidetes	M	Glycosyl hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_81
k59_474786_1	1227266.HMPREF1551_01598	1.33e-33	122.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1I21D@117743|Flavobacteriia,1ERK5@1016|Capnocytophaga	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k59_869490_1	1250006.JHZZ01000001_gene1125	1.63e-100	303.0	COG2207@1|root,COG2207@2|Bacteria,4NGS3@976|Bacteroidetes,1HYVE@117743|Flavobacteriia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k59_869490_2	1121011.AUCB01000001_gene571	6.46e-21	90.5	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia,23H58@178469|Arenibacter	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_1150685_1	1565129.JSFF01000026_gene1274	2.36e-125	380.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,2Q94D@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM glycosyl transferase, family 51	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_79442_1	411154.GFO_0422	7.27e-46	166.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1HX0N@117743|Flavobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_192387_1	411154.GFO_1602	2.18e-141	416.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HZTD@117743|Flavobacteriia	976|Bacteroidetes	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_21154_1	318167.Sfri_0041	4.3e-29	112.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,2Q8HB@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k59_21154_2	398579.Spea_0096	3.9e-44	154.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,2QAZA@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	HemN_C,Radical_SAM
k59_1322695_1	1237149.C900_04822	3.05e-33	120.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
k59_1322695_2	643867.Ftrac_0271	8.52e-26	103.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_701507_1	563040.Saut_2018	1.43e-79	253.0	COG1472@1|root,COG3023@1|root,COG1472@2|Bacteria,COG3023@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2YN15@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glycosyl hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidase_2,Glyco_hydro_3
k59_249016_1	1123518.ARWI01000001_gene436	2.26e-160	452.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,460B1@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_1491404_1	1286106.MPL1_12221	1.9e-78	241.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,46253@72273|Thiotrichales	72273|Thiotrichales	S	Hydrolase, carbon-nitrogen family	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_81541_2	273121.WS0630	2.1e-32	114.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2YPX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_81541_3	563040.Saut_0566	2.28e-70	218.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2YMN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_194656_1	1484460.JSWG01000012_gene1404	2.21e-25	102.0	28MB2@1|root,2ZAPM@2|Bacteria,4NM1C@976|Bacteroidetes,1I004@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194656_2	1046627.BZARG_1309	6.81e-28	111.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_1548531_1	1123514.KB905899_gene1890	4.42e-71	253.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,463V7@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_1325012_1	292415.Tbd_2407	2.23e-38	131.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,1KSH2@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1325012_2	1123367.C666_02045	6.22e-44	149.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,2KWAY@206389|Rhodocyclales	206389|Rhodocyclales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_1325021_1	90814.KL370891_gene1762	2.22e-79	245.0	COG1639@1|root,COG1639@2|Bacteria,1RFEZ@1224|Proteobacteria	1224|Proteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_979769_1	640081.Dsui_0782	4.89e-122	355.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,2KUPE@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
k59_1041276_1	411154.GFO_2875	9.79e-231	660.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_1041279_1	411154.GFO_2338	5.31e-29	104.0	2EVMP@1|root,33P1Q@2|Bacteria,4NXGQ@976|Bacteroidetes,1I6M2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1041279_2	411154.GFO_2339	3.36e-65	207.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1HY4I@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1153043_1	1406840.Q763_00335	8.27e-111	349.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia,2P0JG@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_758078_1	880070.Cycma_3218	1.26e-35	129.0	COG0500@1|root,COG2226@2|Bacteria,4NYCJ@976|Bacteroidetes,47U3P@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_477097_1	268407.PWYN_08635	1.5e-54	193.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,1UMSN@1239|Firmicutes,4IT1W@91061|Bacilli	91061|Bacilli	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,N6_Mtase,TaqI_C
k59_533025_1	572480.Arnit_2959	3.29e-98	295.0	COG0475@1|root,COG0475@2|Bacteria,1N2RV@1224|Proteobacteria,43B2N@68525|delta/epsilon subdivisions,2YT5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_646218_1	1232410.KI421424_gene1746	1.85e-32	118.0	COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,42VRP@68525|delta/epsilon subdivisions,2WSDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_362479_1	1123514.KB905899_gene895	4.14e-220	614.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,45ZS3@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1325057_1	1424334.W822_04430	4.18e-107	343.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,3T1HA@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_816450_1	318161.Sden_2968	3.29e-55	185.0	2DM0S@1|root,317K8@2|Bacteria,1RM4S@1224|Proteobacteria,1S7UJ@1236|Gammaproteobacteria,2QDQJ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_816450_2	392500.Swoo_4127	5.53e-16	75.9	COG3271@1|root,COG3271@2|Bacteria,1PWPF@1224|Proteobacteria,1T9MU@1236|Gammaproteobacteria,2QDGY@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Peptidase C39 family	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	Peptidase_C39
k59_1041304_1	1178825.ALIH01000013_gene502	6.92e-54	177.0	2DJI5@1|root,32UD2@2|Bacteria,4NT32@976|Bacteroidetes,1I3F7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1041304_2	1178825.ALIH01000013_gene503	6.4e-39	138.0	2DJI5@1|root,32UD2@2|Bacteria,4NT32@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1153077_1	1484460.JSWG01000009_gene157	2.83e-10	60.1	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_1153077_2	1380600.AUYN01000007_gene3126	2.81e-74	224.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1I2W7@117743|Flavobacteriia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
k59_927533_1	1178825.ALIH01000003_gene2097	3e-113	330.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,1HX1K@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1379064_1	317025.Tcr_0035	5.82e-99	304.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,460EF@72273|Thiotrichales	72273|Thiotrichales	T	GAF domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_1379064_3	317025.Tcr_0034	3.71e-151	430.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RVP9@1236|Gammaproteobacteria,461M0@72273|Thiotrichales	72273|Thiotrichales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_1379064_4	1123518.ARWI01000001_gene1244	4.63e-36	132.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,461TG@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
k59_362497_1	497321.C664_18302	2.78e-49	161.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,2KWJG@206389|Rhodocyclales	206389|Rhodocyclales	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_362497_2	62928.azo0865	2.99e-49	160.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,2KWH7@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_420114_1	1237149.C900_03443	2.03e-71	234.0	COG1729@1|root,COG1729@2|Bacteria,4PKMW@976|Bacteroidetes,47JRZ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
k59_589181_1	1121931.AUHG01000010_gene798	5.45e-120	355.0	COG0591@1|root,COG0591@2|Bacteria,4NIXN@976|Bacteroidetes,1I0MW@117743|Flavobacteriia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	ko:K03307,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.1	-	-	SSF
k59_1096694_1	1123518.ARWI01000001_gene251	9.03e-147	422.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,46027@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1325091_2	643867.Ftrac_0360	6.71e-39	140.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1204028_1	1121931.AUHG01000013_gene2470	2.98e-94	284.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1204028_2	1121931.AUHG01000013_gene2469	7.04e-204	573.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,1HXPV@117743|Flavobacteriia	976|Bacteroidetes	P	Trk-type K transport systems, membrane components	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1153113_1	929558.SMGD1_1513	2.23e-206	579.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_704172_1	1469557.JSWF01000017_gene2316	1.16e-103	307.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,1HXI9@117743|Flavobacteriia	976|Bacteroidetes	S	Dehydrogenase	-	-	1.1.1.1	ko:K12957,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1776602_1	1123514.KB905899_gene1905	6.86e-86	275.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1QVWQ@1224|Proteobacteria,1T2KZ@1236|Gammaproteobacteria,463U0@72273|Thiotrichales	72273|Thiotrichales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_816501_1	1178825.ALIH01000017_gene665	3.5e-112	326.0	COG2227@1|root,COG2227@2|Bacteria,4PKW0@976|Bacteroidetes,1IJNX@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase domain	cypM_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_816501_2	1178825.ALIH01000017_gene663	5.82e-143	419.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
k59_589214_1	411154.GFO_2763	7.06e-34	117.0	2E6MT@1|root,3318D@2|Bacteria,4NW5M@976|Bacteroidetes,1I51K@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_589214_2	1121931.AUHG01000011_gene1758	1.1e-59	200.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1719484_1	420662.Mpe_B0541	1.95e-90	281.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,1KK96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase	icmF	-	5.4.99.2,5.4.99.63,5.4.99.64	ko:K01847,ko:K01848,ko:K14447,ko:K20906	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_816507_1	56780.SYN_02371	3.17e-07	51.2	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MQ94@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_816507_2	1121430.JMLG01000008_gene1520	2.88e-12	65.9	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,260I1@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1153138_1	411154.GFO_0632	3.93e-17	77.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1HY82@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
k59_1153138_2	1121931.AUHG01000016_gene954	3.63e-68	214.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1HWX9@117743|Flavobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_362554_1	1178825.ALIH01000007_gene1703	5.33e-16	76.3	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1HWYR@117743|Flavobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_1737411_1	1121931.AUHG01000010_gene54	7.96e-68	207.0	COG3324@1|root,COG3324@2|Bacteria,4NQSB@976|Bacteroidetes,1I3KR@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG3324 protein related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1737411_2	1453498.LG45_05800	8.92e-07	49.7	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1HYFZ@117743|Flavobacteriia,2NTT4@237|Flavobacterium	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
k59_1057404_1	1121931.AUHG01000015_gene1201	2.56e-172	513.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_723302_1	572480.Arnit_0306	4e-143	419.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_1680829_1	926562.Oweho_0142	6.43e-80	252.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia,2PAB5@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1737441_1	497321.C664_19868	1.41e-144	420.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2VJUB@28216|Betaproteobacteria,2KVMY@206389|Rhodocyclales	206389|Rhodocyclales	C	acetyl-CoA hydrolase	cat1	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_605417_1	411154.GFO_2281	2.17e-84	260.0	COG0438@1|root,COG0438@2|Bacteria,4NIV3@976|Bacteroidetes,1HZWN@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_154660_1	497321.C664_15073	2.5e-06	49.3	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,2VJTR@28216|Betaproteobacteria,2KUUH@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k59_154660_2	1565129.JSFF01000017_gene2893	4.64e-109	323.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RSJR@1236|Gammaproteobacteria,2Q9IU@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_325498_1	326298.Suden_0447	6.28e-95	281.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_605429_1	745718.JADT01000027_gene2509	2.99e-92	275.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,1HWPP@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
k59_723344_1	1178825.ALIH01000004_gene2968	1.3e-73	224.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I28K@117743|Flavobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_723344_2	983544.Lacal_2023	1.39e-27	105.0	2CBAI@1|root,32REB@2|Bacteria,4NF3F@976|Bacteroidetes,1I330@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_775970_1	1237149.C900_05108	4.16e-92	298.0	COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia	976|Bacteroidetes	C	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
k59_380406_1	929558.SMGD1_0104	3.92e-44	157.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_380406_2	1280694.AUJQ01000001_gene2114	1.1e-07	55.1	COG2199@1|root,COG3287@1|root,COG3287@2|Bacteria,COG3706@2|Bacteria,1TT8G@1239|Firmicutes,24ETN@186801|Clostridia	186801|Clostridia	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,GGDEF
k59_775974_1	1341181.FLJC2902T_10810	6.97e-18	83.2	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia,2NU91@237|Flavobacterium	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_775974_2	1226994.AMZB01000136_gene5064	3.68e-56	194.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1YFEA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_268186_1	1123514.KB905899_gene1986	2.41e-121	372.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,461S8@72273|Thiotrichales	72273|Thiotrichales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1741303_1	563040.Saut_1470	2.69e-06	48.1	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2YMVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1175060_1	983544.Lacal_0579	4.56e-88	272.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1175060_2	504487.JCM19302_249	1.28e-110	325.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1175060_3	391587.KAOT1_04125	9.51e-79	242.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,1HX82@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_157718_1	572480.Arnit_2835	9.6e-110	332.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_1060924_1	929558.SMGD1_0133	4.56e-167	479.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_1001192_1	323850.Shew_0912	1.85e-38	129.0	29UIN@1|root,30FVV@2|Bacteria,1QMV4@1224|Proteobacteria,1TK5K@1236|Gammaproteobacteria,2QCNV@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1626543_1	563040.Saut_0906	4.7e-88	275.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_1741345_1	1380600.AUYN01000012_gene2972	2.28e-258	732.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_1798283_1	1250278.JQNQ01000001_gene3535	6.17e-90	288.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k59_1220520_1	411154.GFO_0176	1.64e-101	300.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_1399958_1	264730.PSPPH_1342	1.83e-25	98.2	COG3323@1|root,COG3323@2|Bacteria,1MZF5@1224|Proteobacteria,1S8WV@1236|Gammaproteobacteria,1Z7ZF@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11022	ko05134,map05134	-	-	-	ko00000,ko00001,ko02042	-	-	-	-
k59_552541_1	572480.Arnit_1359	4.07e-60	197.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42NDE@68525|delta/epsilon subdivisions,2YMNM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase, large subunit	hupL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_836381_1	1086011.HJ01_00398	5.84e-10	59.7	COG0521@1|root,COG0521@2|Bacteria,4NHV5@976|Bacteroidetes,1HXT5@117743|Flavobacteriia,2NUQE@237|Flavobacterium	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_1001231_1	458817.Shal_0800	8.87e-143	416.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,2QAD3@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ahpF	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k59_1001233_1	572480.Arnit_1245	4.55e-95	280.0	29D2R@1|root,3000T@2|Bacteria,1RG31@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	-
k59_1001233_2	572480.Arnit_1244	9.88e-71	214.0	COG2346@1|root,COG2346@2|Bacteria,1Q5UZ@1224|Proteobacteria,42U39@68525|delta/epsilon subdivisions,2YPTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_103456_1	929558.SMGD1_0413	1.81e-92	279.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,42Q1Y@68525|delta/epsilon subdivisions,2YNR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_946080_1	1123054.KB907705_gene2406	1.05e-44	155.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1WX83@135613|Chromatiales	135613|Chromatiales	S	PFAM YicC-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_216239_2	563040.Saut_1696	2.29e-76	229.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033743,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	iAF1260.b1778,iB21_1397.B21_01735,iBWG_1329.BWG_1591,iE2348C_1286.E2348C_1905,iEC042_1314.EC042_1944,iEC55989_1330.EC55989_1947,iECBD_1354.ECBD_1866,iECB_1328.ECB_01747,iECDH10B_1368.ECDH10B_1916,iECDH1ME8569_1439.ECDH1ME8569_1722,iECD_1391.ECD_01747,iECH74115_1262.ECH74115_2502,iECIAI39_1322.ECIAI39_1275,iECNA114_1301.ECNA114_1824,iECO103_1326.ECO103_1964,iECP_1309.ECP_1726,iECSE_1348.ECSE_1949,iECSF_1327.ECSF_1639,iECSP_1301.ECSP_2350,iECUMN_1333.ECUMN_2067,iECW_1372.ECW_m1947,iECs_1301.ECs2487,iEKO11_1354.EKO11_1997,iETEC_1333.ETEC_1810,iEcDH1_1363.EcDH1_1864,iEcE24377_1341.EcE24377A_2002,iEcSMS35_1347.EcSMS35_1413,iG2583_1286.G2583_2225,iJO1366.b1778,iLF82_1304.LF82_1402,iNRG857_1313.NRG857_08905,iPC815.YPO2158,iSSON_1240.SSON_1385,iWFL_1372.ECW_m1947,iY75_1357.Y75_RS09320,iYL1228.KPN_01198,iZ_1308.Z2817	SelR
k59_1515861_1	929558.SMGD1_0150	3.64e-120	350.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_383954_1	572480.Arnit_0234	3.66e-68	210.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2YPNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1288420_1	1565129.JSFF01000005_gene2294	5.96e-95	306.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,2Q963@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_1569784_2	1121912.AUHD01000007_gene470	2.3e-228	629.0	COG2152@1|root,COG2152@2|Bacteria,4NGI7@976|Bacteroidetes,1HXP6@117743|Flavobacteriia	976|Bacteroidetes	G	glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
k59_1569784_3	1121887.AUDK01000017_gene43	9.36e-154	449.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1HWTC@117743|Flavobacteriia,2NV3H@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1288428_1	1125863.JAFN01000001_gene2170	1.78e-05	46.2	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_1288428_2	1123514.KB905903_gene353	3.07e-28	103.0	2DNUJ@1|root,32Z85@2|Bacteria,1QTZU@1224|Proteobacteria,1T1JC@1236|Gammaproteobacteria,46355@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF2789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2789
k59_1288428_3	1123514.KB905903_gene352	8.08e-15	71.2	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,460T6@72273|Thiotrichales	72273|Thiotrichales	L	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_1798346_1	1168067.JAGP01000001_gene1237	5.25e-96	291.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,45ZMJ@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1175171_1	1123518.ARWI01000001_gene1939	1.29e-146	422.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,45ZMN@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1175171_2	90814.KL370891_gene1700	1.15e-86	261.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,460SF@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_43684_4	1273742.M1HNA7_9CAUD	2.16e-30	118.0	4QAZY@10239|Viruses,4QV2T@35237|dsDNA viruses  no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae	10699|Siphoviridae	S	peptidoglycan catabolic process	-	GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003	-	-	-	-	-	-	-	-	-	-	-
k59_779938_1	411154.GFO_2142	7.34e-126	381.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1684658_2	1172190.M947_08030	2.03e-148	441.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,HAMP,MCPsignal,NIT
k59_1220612_1	877421.AUJT01000043_gene974	1.96e-13	65.9	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,27PR8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k59_1684665_1	572480.Arnit_0511	6.76e-106	311.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2YMHA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_43708_2	1123248.KB893324_gene1660	6.19e-43	157.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes,1IR1S@117747|Sphingobacteriia	976|Bacteroidetes	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_836444_1	244582.JQAK01000001_gene1678	2.24e-28	119.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2U48V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
k59_836444_2	926559.JoomaDRAFT_2498	1.36e-14	72.4	COG5360@1|root,COG5360@2|Bacteria,4NHMA@976|Bacteroidetes,1I0VS@117743|Flavobacteriia	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
k59_216314_1	572480.Arnit_2846	2.02e-127	370.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1001320_1	572480.Arnit_2421	2.43e-11	68.2	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_2,TPR_8,VWA_2
k59_1001320_2	572480.Arnit_2422	1.38e-16	77.8	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42PA7@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_441285_1	313624.NSP_23290	5.75e-48	173.0	COG0517@1|root,COG1082@1|root,COG2089@1|root,COG0517@2|Bacteria,COG1082@2|Bacteria,COG2089@2|Bacteria,1G4IG@1117|Cyanobacteria,1HNGR@1161|Nostocales	1117|Cyanobacteria	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,CBS,NeuB,SAF
k59_1456659_1	467661.RKLH11_3369	2.94e-05	45.8	COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,2TQM4@28211|Alphaproteobacteria,3ZGMU@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	K	Transcriptional regulator, LacI family	MA20_27200	-	-	ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k59_216323_1	1380600.AUYN01000006_gene623	3.18e-44	144.0	2E389@1|root,32Y7Y@2|Bacteria,4NW5R@976|Bacteroidetes,1I5BX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1660
k59_216323_2	1178825.ALIH01000001_gene2307	4.38e-31	111.0	2E389@1|root,32Y7Y@2|Bacteria,4NW5R@976|Bacteroidetes,1I5BX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216323_3	1380600.AUYN01000006_gene625	1.96e-135	390.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1HWNB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_552674_1	929558.SMGD1_2862	4.35e-103	320.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria	1224|Proteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_836463_1	269482.Bcep1808_5356	2.1e-98	296.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2VPA1@28216|Betaproteobacteria,1K1FT@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141,PHB_depo_C
k59_1347335_1	944547.ABLL_0656	1.02e-11	62.4	29QY9@1|root,30BZ3@2|Bacteria,1QTGR@1224|Proteobacteria,42VBX@68525|delta/epsilon subdivisions,2YQ83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1347335_2	572480.Arnit_0773	9.9e-60	192.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_668417_1	1123518.ARWI01000001_gene2100	5.34e-50	177.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_103573_2	62928.azo0098	3.23e-52	175.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,2KUKQ@206389|Rhodocyclales	206389|Rhodocyclales	S	protein containing LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_1061110_1	1123514.KB905899_gene947	3.12e-124	372.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,45ZWA@72273|Thiotrichales	72273|Thiotrichales	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
k59_1118658_1	1123514.KB905899_gene1569	6.83e-63	214.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,460B9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1175271_1	1223521.BBJX01000004_gene2431	3.2e-54	181.0	COG1028@1|root,COG1028@2|Bacteria,1QU4S@1224|Proteobacteria,2VH03@28216|Betaproteobacteria,4ABN7@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1175274_1	563040.Saut_0577	6.59e-59	193.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1175274_2	326298.Suden_1601	4.5e-52	174.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YN0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_1684757_1	326298.Suden_1431	1.09e-89	285.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1220711_1	688270.Celal_4110	1.3e-86	266.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1HXMQ@117743|Flavobacteriia,1F91A@104264|Cellulophaga	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_1220711_2	616991.JPOO01000001_gene4247	8.18e-11	62.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_668457_1	563040.Saut_1836	1.01e-84	267.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_329138_1	317025.Tcr_1101	3.93e-90	285.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,4603V@72273|Thiotrichales	72273|Thiotrichales	C	Isocitrate dehydrogenase NADP-dependent, monomeric type	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_271453_1	1123518.ARWI01000001_gene1824	6.45e-61	207.0	29DE2@1|root,300BX@2|Bacteria,1NC7M@1224|Proteobacteria,1SFWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_552724_1	411154.GFO_3288	6.06e-134	394.0	COG0664@1|root,COG0664@2|Bacteria,4NEWA@976|Bacteroidetes,1HWPV@117743|Flavobacteriia	976|Bacteroidetes	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1001398_1	525898.Sdel_1821	2.4e-21	95.1	COG0715@1|root,COG2199@1|root,COG3221@1|root,COG0715@2|Bacteria,COG3221@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43D09@68525|delta/epsilon subdivisions,2YPBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	PT	TIGRFAM diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,Phosphonate-bd
k59_63328_2	1178825.ALIH01000002_gene1097	5.34e-119	341.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1HXJN@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_63328_4	1353276.JADR01000001_gene290	1.55e-114	337.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1HX64@117743|Flavobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_289172_1	1415778.JQMM01000001_gene2140	5.98e-84	253.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1J6H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH
k59_1758017_1	1191523.MROS_1086	1.48e-23	107.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_853420_1	326298.Suden_0056	4.7e-87	268.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2YMX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0903m	Acetate_kinase
k59_1418760_2	886377.Murru_2389	1.91e-07	52.8	COG3637@1|root,COG3637@2|Bacteria,4NTE4@976|Bacteroidetes,1I47I@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1475034_1	189425.PGRAT_32195	0.000584	47.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1VJGY@1239|Firmicutes,4HQEW@91061|Bacilli,26RAU@186822|Paenibacillaceae	91061|Bacilli	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_345107_1	945713.IALB_1289	4.21e-85	275.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_458952_1	1219076.N646_3651	3.29e-21	92.4	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1Y2N0@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1306393_1	1380600.AUYN01000001_gene2670	0.0	1270.0	COG1345@1|root,COG1361@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
k59_6456_1	317025.Tcr_0448	1.02e-47	160.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,461C6@72273|Thiotrichales	72273|Thiotrichales	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
k59_6456_2	1123518.ARWI01000001_gene1987	5.17e-23	93.6	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein affecting phage T7 exclusion by the F plasmid	fxsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
k59_119569_1	1121931.AUHG01000012_gene2895	7.91e-55	176.0	2AQR4@1|root,31FYV@2|Bacteria,4NQYS@976|Bacteroidetes,1I3DS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_119569_2	411154.GFO_1012	7.71e-108	311.0	COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,1HXWP@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1023731_1	1415778.JQMM01000001_gene609	2.25e-40	142.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RNB1@1236|Gammaproteobacteria,1J4UW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_853455_1	886377.Murru_0054	9.61e-45	165.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1HXNC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_740884_1	411154.GFO_2784	2.86e-71	218.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_740884_2	1121931.AUHG01000011_gene1740	4.25e-100	296.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes,1HYCI@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k59_740888_1	1178825.ALIH01000020_gene2719	1.3e-91	273.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1HYRW@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_740888_2	1107311.Q767_04250	0.000147	43.1	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia,2NW2C@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
k59_1023760_1	1121931.AUHG01000010_gene413	5e-148	422.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1079231_1	1317124.DW2_07807	1.06e-50	163.0	29EYI@1|root,301WB@2|Bacteria,1PU2J@1224|Proteobacteria,2V5UT@28211|Alphaproteobacteria,2XNMV@285107|Thioclava	28211|Alphaproteobacteria	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k59_740892_1	1178825.ALIH01000008_gene808	1.91e-90	286.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_233051_1	1443665.JACA01000073_gene2039	4.57e-165	471.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia,2YI3G@290174|Aquimarina	976|Bacteroidetes	E	Peptidase dimerisation domain	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_233051_2	1178825.ALIH01000001_gene2465	7.19e-78	239.0	COG0697@1|root,COG0697@2|Bacteria,4NH4Y@976|Bacteroidetes,1HXJX@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_63396_1	1380600.AUYN01000010_gene904	1.84e-204	570.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1HXIE@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_1361625_1	1441930.Z042_21460	3.5e-08	56.2	COG3631@1|root,COG3631@2|Bacteria,1RGEA@1224|Proteobacteria,1RUZU@1236|Gammaproteobacteria,404E9@613|Serratia	1236|Gammaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
k59_1191199_1	572480.Arnit_1553	7.91e-112	331.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_1475100_1	1178825.ALIH01000020_gene2740	1.02e-90	267.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1I1BI@117743|Flavobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_797811_1	504487.JCM19302_765	9.21e-30	111.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_797811_2	1392490.JHZX01000001_gene2804	1.12e-249	687.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1HWJG@117743|Flavobacteriia	976|Bacteroidetes	S	protein with a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_797811_3	983544.Lacal_1962	4.89e-12	65.9	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1HX9Z@117743|Flavobacteriia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
k59_1136113_1	1178825.ALIH01000005_gene351	8.37e-162	470.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia	976|Bacteroidetes	O	Molecular chaperone	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_1136113_2	1168034.FH5T_07240	1.33e-73	261.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3
k59_1136113_3	1250232.JQNJ01000001_gene2399	1.05e-91	274.0	COG2258@1|root,COG2258@2|Bacteria,4NGQN@976|Bacteroidetes,1I049@117743|Flavobacteriia	976|Bacteroidetes	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_1136113_4	1380600.AUYN01000001_gene2715	7.27e-246	681.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1136113_5	1380600.AUYN01000001_gene2716	4.25e-38	133.0	2EAJN@1|root,334NG@2|Bacteria,4NV3P@976|Bacteroidetes,1I5JW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1136113_6	1506583.JQJY01000002_gene1775	4.41e-23	93.2	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,1I0Q1@117743|Flavobacteriia,2NS8W@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1588733_1	326297.Sama_0004	3.23e-47	160.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,2Q9W1@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	frmA	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1588733_2	1415754.JQMK01000002_gene2139	1.26e-05	46.2	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,4648K@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	IV02_27905	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_289260_2	929558.SMGD1_2133	1.31e-75	235.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2YMIV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1191211_1	572480.Arnit_0781	1.3e-125	360.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_345183_1	765912.Thimo_2360	7.3e-121	364.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1WXM0@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_345183_2	90814.KL370892_gene1950	9.19e-27	99.4	295HQ@1|root,2ZSV9@2|Bacteria,1P5E8@1224|Proteobacteria,1SVNZ@1236|Gammaproteobacteria,463H8@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_797838_1	717772.THIAE_01755	1.78e-12	71.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461Z4@72273|Thiotrichales	72273|Thiotrichales	NT	helical bimodular (HBM) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
k59_967010_1	323850.Shew_0052	2.64e-61	196.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,1RY8Q@1236|Gammaproteobacteria,2QACX@267890|Shewanellaceae	1236|Gammaproteobacteria	L	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
k59_967010_2	1187848.AJYQ01000093_gene3449	3.19e-21	92.8	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XSDF@135623|Vibrionales	135623|Vibrionales	T	containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1531477_1	563040.Saut_2027	5.12e-116	347.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2YNS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COGs COG0025 NhaP-type Na H and K H antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
k59_1531477_2	929558.SMGD1_1220	3.07e-67	221.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1645117_1	90814.KL370892_gene2117	2.03e-87	277.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_8,PAS_9,dCache_1
k59_1645117_2	1123514.KB905900_gene2177	5.94e-61	193.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,4611S@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.30,3.2.2.9	ko:K01243,ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_910400_1	1123236.KB899376_gene902	2.85e-25	102.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,466WG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818	-	-	-	-	-	-	-	-	-	-	DUF1289,NUDIX
k59_1136159_1	159087.Daro_2046	4.35e-52	186.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,2KUR9@206389|Rhodocyclales	206389|Rhodocyclales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k59_571696_1	572480.Arnit_2872	1.54e-68	224.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_853539_1	1121931.AUHG01000011_gene2422	2.68e-107	313.0	28P6F@1|root,2ZC14@2|Bacteria,4NMZU@976|Bacteroidetes,1I1J4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_402409_1	1123518.ARWI01000001_gene2218	1.37e-64	197.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,4610R@72273|Thiotrichales	72273|Thiotrichales	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k59_402409_2	317025.Tcr_0420	8.05e-35	123.0	2CH0Z@1|root,33H8V@2|Bacteria,1NMM6@1224|Proteobacteria,1STI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_289313_1	1336803.PHEL49_1618	4.33e-124	393.0	COG5498@1|root,COG5498@2|Bacteria,4NJUD@976|Bacteroidetes,1IG6T@117743|Flavobacteriia,3VW2U@52959|Polaribacter	976|Bacteroidetes	M	Glycosyl hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_81
k59_1306518_1	1131730.BAVI_21593	7.12e-65	209.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,1ZD7C@1386|Bacillus	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k59_1306518_2	316274.Haur_1503	1.3e-80	254.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k59_1079316_1	326298.Suden_0354	2.27e-143	444.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_628350_2	1317122.ATO12_00605	6.41e-84	253.0	COG1045@1|root,COG1045@2|Bacteria,4NUIU@976|Bacteroidetes,1I56E@117743|Flavobacteriia,2YJE2@290174|Aquimarina	976|Bacteroidetes	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_628350_3	980584.AFPB01000153_gene362	9.76e-76	239.0	28IAS@1|root,2Z8DC@2|Bacteria,4NFA2@976|Bacteroidetes,1HYWQ@117743|Flavobacteriia,406VN@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	EpsG family	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
k59_967039_1	563040.Saut_1016	7.95e-141	429.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1306528_1	1347342.BN863_24420	2.87e-82	246.0	COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,1I1D0@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_119705_1	1121875.KB907546_gene2492	1.48e-172	493.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
k59_853578_1	62928.azo3272	6.44e-23	97.1	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VHM2@28216|Betaproteobacteria,2KVFD@206389|Rhodocyclales	206389|Rhodocyclales	M	PEP-CTERM exosortase 1-associated glycosyltransferase, Daro_2409 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
k59_853578_2	62928.azo3271	1.63e-96	298.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,2KVYU@206389|Rhodocyclales	206389|Rhodocyclales	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_345261_1	1123518.ARWI01000001_gene1496	2.64e-127	366.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,45ZNV@72273|Thiotrichales	72273|Thiotrichales	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,MipZ
k59_1248987_1	1121931.AUHG01000010_gene710	2.32e-67	211.0	COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,1I5ZB@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1758211_1	1565129.JSFF01000003_gene2227	2.9e-127	392.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q9AP@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_402455_1	946077.W5A_06875	7.49e-20	84.0	COG0824@1|root,COG0824@2|Bacteria,4NSIG@976|Bacteroidetes,1I42Y@117743|Flavobacteriia	976|Bacteroidetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
k59_402455_2	1178825.ALIH01000002_gene1103	3.08e-242	684.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes,1HYM1@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
k59_233164_1	504487.JCM19302_1414	4.18e-169	481.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
k59_233164_2	278957.ABEA03000112_gene1377	1.22e-297	863.0	COG3250@1|root,COG3250@2|Bacteria,46U2Y@74201|Verrucomicrobia,3K7KS@414999|Opitutae	414999|Opitutae	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_233164_3	983544.Lacal_1428	6.87e-53	170.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_345279_2	1123514.KB905899_gene1688	3.36e-43	153.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,46016@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_514872_3	616991.JPOO01000001_gene3548	1.86e-44	153.0	COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
k59_1023911_2	1121007.AUML01000014_gene2866	4.19e-42	145.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,1I1E1@117743|Flavobacteriia,2YIZ8@290174|Aquimarina	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
k59_1588850_1	1046627.BZARG_515	4.02e-77	237.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1HYFZ@117743|Flavobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
k59_1588850_2	1380600.AUYN01000006_gene587	2.2e-115	334.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1HYHB@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
k59_1588850_3	1137281.D778_01585	4.06e-230	639.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1HWQ7@117743|Flavobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_799951_1	1122225.AULQ01000009_gene321	8.31e-11	57.4	2EITG@1|root,33CIS@2|Bacteria,4NXPE@976|Bacteroidetes,1I6D9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_475381_3	1380600.AUYN01000006_gene816	1.65e-112	326.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_79952_5	1085623.GNIT_1811	5.26e-25	102.0	COG0073@1|root,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890,ko:K06878	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,RNA_ligase,tRNA_bind
k59_305553_1	1172190.M947_09740	4.23e-80	248.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2YMHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_305553_2	1172190.M947_09735	2.42e-19	85.1	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2YT6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_1265153_1	1120999.JONM01000035_gene4198	1.12e-61	218.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_135095_1	443143.GM18_0097	3.76e-74	241.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_644603_1	1565129.JSFF01000009_gene1805	1.1e-95	294.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,2Q9FP@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	Type II and III secretion system protein	mshL	-	-	ko:K12282	-	-	-	-	ko00000,ko02044	-	-	-	STN,Secretin,Secretin_N_2
k59_192993_1	575788.VS_II0715	1.31e-25	105.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XT2Z@135623|Vibrionales	135623|Vibrionales	E	COG1448 Aspartate tyrosine aromatic aminotransferase	-	-	2.6.1.1	ko:K00813	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_192993_2	349521.HCH_02798	3.56e-18	84.7	COG0697@1|root,COG0697@2|Bacteria,1RI87@1224|Proteobacteria,1S4HT@1236|Gammaproteobacteria,1XJNZ@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_135112_1	1178825.ALIH01000013_gene569	8.7e-178	504.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_418429_1	90814.KL370891_gene1557	4.56e-24	96.7	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,4624W@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_418429_2	317025.Tcr_0570	3.79e-140	423.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_870106_1	411154.GFO_0389	1.7e-137	399.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,1HWX3@117743|Flavobacteriia	976|Bacteroidetes	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_978701_1	1123037.AUDE01000005_gene3055	2.56e-28	105.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_978701_2	1137281.D778_00611	7.14e-136	389.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
k59_135144_1	929558.SMGD1_1153	2.15e-29	109.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_135144_2	326298.Suden_2020	3.72e-16	73.6	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2YNVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_475456_1	411154.GFO_1628	0.000423	41.2	COG0745@1|root,COG0745@2|Bacteria,4NU4J@976|Bacteroidetes,1I454@117743|Flavobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_475456_2	926559.JoomaDRAFT_3645	5.09e-68	214.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1HY0C@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_587508_1	1244869.H261_01926	5.47e-18	89.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQ4H@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_7,PAS_9,dCache_1,dCache_2
k59_587508_2	1042375.AFPL01000026_gene3682	2.63e-18	86.7	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,46469@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
k59_475485_1	1232410.KI421418_gene2422	5.26e-74	234.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,43VZ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SelR domain	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_80060_1	1121957.ATVL01000006_gene3414	3.05e-22	92.8	COG3184@1|root,COG3184@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
k59_814769_1	572480.Arnit_2990	4.93e-121	361.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2YN6M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	iIT341.HP0140,iIT341.HP0141	Lactate_perm
k59_360816_1	411154.GFO_1623	1.71e-82	248.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_360816_2	1121931.AUHG01000012_gene2553	5.12e-63	211.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1HX0J@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_1717868_1	411154.GFO_2693	2.71e-32	114.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1I1ZH@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_1717868_2	1121931.AUHG01000011_gene1829	4.33e-52	170.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1HZU1@117743|Flavobacteriia	976|Bacteroidetes	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_249696_1	655815.ZPR_0912	4.94e-43	148.0	COG2273@1|root,COG2273@2|Bacteria,4NF91@976|Bacteroidetes,1I1TV@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Glyco_hydro_16,Glyco_hydro_43
k59_249696_2	616991.JPOO01000003_gene2349	2.84e-217	609.0	2C31A@1|root,2Z7UP@2|Bacteria,4NECU@976|Bacteroidetes,1HX63@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_249696_3	143224.JQMD01000002_gene3005	1.76e-87	268.0	COG0665@1|root,COG0665@2|Bacteria,4NFPQ@976|Bacteroidetes,1HX5D@117743|Flavobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase TIGR03364	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1151385_1	1392490.JHZX01000001_gene2039	8.47e-90	285.0	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,1HWVG@117743|Flavobacteriia	976|Bacteroidetes	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pec_lyase,Pectinesterase
k59_418525_1	1442598.JABW01000027_gene899	1.63e-175	498.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42Q8J@68525|delta/epsilon subdivisions,2YMVG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
k59_531472_1	1317122.ATO12_18060	4.04e-14	76.3	COG2207@1|root,COG2207@2|Bacteria,4NEU2@976|Bacteroidetes,1IIQ1@117743|Flavobacteriia,2YJ0T@290174|Aquimarina	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_135229_1	929558.SMGD1_0773	3.94e-34	123.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42N4V@68525|delta/epsilon subdivisions,2YN04@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	rluA	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_135229_2	326298.Suden_0446	1.75e-122	360.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_80110_1	313596.RB2501_07290	9.82e-109	343.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1547060_1	2340.JV46_06030	0.000128	50.8	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1J8GC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
k59_305713_1	1380600.AUYN01000007_gene3426	1.77e-128	374.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_360879_1	43228.XP_007735246.1	1.94e-24	100.0	COG1085@1|root,KOG2958@2759|Eukaryota,38ED2@33154|Opisthokonta,3NU1J@4751|Fungi,3QK2X@4890|Ascomycota,20ENC@147545|Eurotiomycetes,3MU2M@451870|Chaetothyriomycetidae	4751|Fungi	H	Galactose-1-phosphate uridylyltransferase	GAL7	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0019438,GO:0019538,GO:0033499,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042125,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046835,GO:0046872,GO:0046914,GO:0052573,GO:0052574,GO:0055086,GO:0070085,GO:0070569,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_80128_1	411154.GFO_3297	4.91e-20	84.7	COG2825@1|root,COG2825@2|Bacteria,4NMEY@976|Bacteroidetes,1IMJF@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_80128_2	411154.GFO_3296	3.97e-51	164.0	2CNQU@1|root,32SHJ@2|Bacteria,4NSMZ@976|Bacteroidetes,1I4C3@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_531499_1	563040.Saut_1603	1.68e-29	117.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_531499_2	929558.SMGD1_1907	4.2e-115	338.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42RI9@68525|delta/epsilon subdivisions,2YP40@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_702308_1	317025.Tcr_1136	4.29e-118	351.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,461KB@72273|Thiotrichales	72273|Thiotrichales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1434370_1	1197477.IA57_09225	1.04e-69	219.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1HY56@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_1434370_2	391603.FBALC1_13107	7.05e-72	217.0	COG0662@1|root,COG0662@2|Bacteria,4NQIP@976|Bacteroidetes,1I24Z@117743|Flavobacteriia	976|Bacteroidetes	G	Ethanolamine utilisation protein EutQ	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_305728_1	1123228.AUIH01000005_gene611	3.9e-62	202.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1XHF5@135619|Oceanospirillales	135619|Oceanospirillales	U	general secretion pathway protein	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_475578_1	305700.B447_02386	2.28e-117	366.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,2KWRC@206389|Rhodocyclales	206389|Rhodocyclales	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_644770_1	504487.JCM19302_2670	1.34e-63	200.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,1HXD6@117743|Flavobacteriia	976|Bacteroidetes	L	double-stranded RNA RNA-DNA hybrid binding protein	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
k59_644770_2	746697.Aeqsu_2123	2.18e-175	506.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_702314_1	1380600.AUYN01000001_gene2768	4.51e-62	195.0	COG2318@1|root,COG2318@2|Bacteria,4NRMF@976|Bacteroidetes,1I3NK@117743|Flavobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_1377564_1	1178825.ALIH01000015_gene1916	1.25e-57	189.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1HWKD@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
k59_1377564_2	391587.KAOT1_05662	1.31e-21	90.1	2D1GA@1|root,32TAN@2|Bacteria,4NSH6@976|Bacteroidetes,1I4HJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1151450_1	1123518.ARWI01000001_gene2185	1.37e-222	627.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_1605916_1	1172190.M947_00870	1.1e-94	280.0	COG0778@1|root,COG0778@2|Bacteria,1RFM9@1224|Proteobacteria,43AKB@68525|delta/epsilon subdivisions,2YT1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1717970_1	709032.Sulku_0366	5.38e-46	157.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2YMTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_1717970_2	1172190.M947_03625	6.75e-85	258.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_756547_1	1121875.KB907547_gene3444	3.47e-115	351.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1039823_1	1172190.M947_03035	2.04e-132	395.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1774939_1	1123518.ARWI01000001_gene2083	2.58e-90	273.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,460DK@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_587656_1	1121931.AUHG01000010_gene752	2.05e-97	296.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1095128_1	991.IW20_25505	6.01e-80	247.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia,2NSSV@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_1095128_2	1121890.AUDO01000001_gene709	1.31e-06	48.9	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia,2NSVG@237|Flavobacterium	976|Bacteroidetes	G	Transketolase	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1777163_1	929558.SMGD1_1675	4.04e-102	307.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_980196_1	395493.BegalDRAFT_0154	1.11e-33	134.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,45ZRI@72273|Thiotrichales	72273|Thiotrichales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_252086_1	929558.SMGD1_1025	3.61e-84	263.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,43CEV@68525|delta/epsilon subdivisions,2YRH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_872292_1	1122225.AULQ01000007_gene2363	3.59e-26	110.0	COG0495@1|root,COG0495@2|Bacteria,4PKSC@976|Bacteroidetes,1IJEG@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
k59_872292_2	1313421.JHBV01000027_gene1737	7.14e-05	44.3	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
k59_1777178_1	90814.KL370891_gene119	3.75e-146	424.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales	72273|Thiotrichales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1379612_1	1123518.ARWI01000001_gene46	3.31e-116	347.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RSJI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GGDEF
k59_1608195_1	1046627.BZARG_1935	1.75e-114	344.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_195316_1	323850.Shew_2096	8.58e-124	371.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,2Q9C1@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c45100	ThiC-associated,ThiC_Rad_SAM
k59_420701_1	1237149.C900_03690	3.07e-76	245.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,47MKB@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_252121_1	1286106.MPL1_12226	3.01e-81	245.0	COG0454@1|root,COG0454@2|Bacteria,1RDBA@1224|Proteobacteria,1S225@1236|Gammaproteobacteria,46199@72273|Thiotrichales	72273|Thiotrichales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_252121_2	243233.MCA1820	3.11e-64	199.0	COG3631@1|root,COG3631@2|Bacteria,1RH08@1224|Proteobacteria,1S4RF@1236|Gammaproteobacteria,1XF90@135618|Methylococcales	135618|Methylococcales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_252121_3	1380391.JIAS01000013_gene3417	6.72e-11	72.8	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2JQ0U@204441|Rhodospirillales	204441|Rhodospirillales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_1379634_1	929558.SMGD1_1981	7.95e-45	152.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2YR7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k59_1379634_2	929558.SMGD1_1656	2.9e-61	196.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2YNS0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_1663677_1	760117.JN27_15930	1.25e-16	75.1	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,4742W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_1115028_2	232346.JHQL01000004_gene1562	1.86e-18	79.0	COG4321@1|root,COG4321@2|Bacteria,1MZP2@1224|Proteobacteria,1S865@1236|Gammaproteobacteria,1XK3D@135619|Oceanospirillales	135619|Oceanospirillales	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_4
k59_1171731_1	398579.Spea_0825	1.73e-134	393.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,2Q8UA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k59_1794832_1	1265503.KB905175_gene3973	1.54e-12	63.9	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,2Q76F@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k59_1794832_2	326298.Suden_2099	4.39e-73	221.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2YPJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_1343690_1	1304885.AUEY01000001_gene3190	3.77e-36	135.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2MJB7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_1453605_1	929558.SMGD1_1451	8.57e-195	567.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k59_380586_1	313603.FB2170_07974	1.86e-106	324.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1I09M@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_723500_1	563040.Saut_1680	1.08e-133	396.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2YTG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_834231_1	317025.Tcr_1778	4e-116	362.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,45ZY9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_325674_1	94122.Shewana3_1486	9.84e-98	304.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,2Q9HG@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0007049,GO:0007059,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0022402,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051304,GO:0071704,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_943071_1	1178825.ALIH01000006_gene1405	2.72e-205	580.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
k59_943071_2	1380600.AUYN01000010_gene917	8.44e-86	256.0	COG0431@1|root,COG0431@2|Bacteria,4NNMA@976|Bacteroidetes,1I22A@117743|Flavobacteriia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_943071_3	1178825.ALIH01000006_gene1403	1.87e-34	120.0	COG2388@1|root,COG2388@2|Bacteria,4NUS6@976|Bacteroidetes,1I57A@117743|Flavobacteriia	976|Bacteroidetes	S	(GNAT) family	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
k59_943071_4	1123037.AUDE01000010_gene2323	9.82e-77	231.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1I2YC@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_943071_5	1178825.ALIH01000006_gene1401	3.77e-91	271.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_494994_1	929558.SMGD1_0654	1.15e-90	276.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_268364_1	944547.ABLL_2631	3.02e-209	581.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria	1224|Proteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_40807_1	90814.KL370892_gene2072	2.26e-107	327.0	COG3173@1|root,COG3173@2|Bacteria,1Q5UX@1224|Proteobacteria,1RS6I@1236|Gammaproteobacteria,462D2@72273|Thiotrichales	72273|Thiotrichales	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_943088_1	62928.azo2074	2.27e-47	163.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2VJE2@28216|Betaproteobacteria,2KV9U@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k59_943088_2	1216976.AX27061_0701	1.95e-17	80.9	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2VI2M@28216|Betaproteobacteria,3T5UC@506|Alcaligenaceae	28216|Betaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_1115108_1	301.JNHE01000004_gene1614	2.31e-80	254.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1YDPI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_605660_1	1219065.VPR01S_40_00040	2.45e-36	134.0	28JYZ@1|root,2Z9P5@2|Bacteria,1NSW8@1224|Proteobacteria,1SKNF@1236|Gammaproteobacteria,1Y0J1@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_605660_2	233412.HD_1417	1.28e-05	46.2	2E36R@1|root,32Y6F@2|Bacteria,1N9BN@1224|Proteobacteria,1SI0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100092_1	1336233.JAEH01000043_gene3864	3.88e-56	184.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,2Q9HP@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_100092_2	323850.Shew_1188	1.4e-134	384.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,2Q9EQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_100092_3	1565129.JSFF01000005_gene2397	5.82e-12	65.1	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,2Q9XQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.193,3.5.4.26	ko:K01498,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524	RibD_C,dCMP_cyt_deam_1
k59_889643_1	1565129.JSFF01000002_gene3516	8.22e-90	271.0	COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,1RNYQ@1236|Gammaproteobacteria,2Q8QF@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator, LysR family	-	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_723558_1	1565314.OA34_02565	3.86e-78	240.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2YMVR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_723558_2	760154.Sulba_0526	7.65e-56	184.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M19@68525|delta/epsilon subdivisions,2YMBQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_40816_1	655815.ZPR_3421	2.45e-87	275.0	COG3505@1|root,COG3505@2|Bacteria,4NFHI@976|Bacteroidetes,1HWU1@117743|Flavobacteriia	976|Bacteroidetes	U	Type IV secretory pathway	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C,TrwB_AAD_bind,YWFCY
k59_40816_2	1249997.JHZW01000003_gene2263	3.21e-28	102.0	COG1813@1|root,COG1813@2|Bacteria,4PKWR@976|Bacteroidetes,1IJMY@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_26,HTH_3,Peptidase_S24
k59_40816_3	926559.JoomaDRAFT_2965	2.74e-144	417.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia	976|Bacteroidetes	H	cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_154894_1	1123392.AQWL01000010_gene2283	1.36e-22	102.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2WGGY@28216|Betaproteobacteria,1KSCB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_723577_1	1123514.KB905899_gene492	5.96e-102	313.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,4606K@72273|Thiotrichales	72273|Thiotrichales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_723577_2	1123401.JHYQ01000005_gene192	4.15e-50	177.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,45ZR1@72273|Thiotrichales	72273|Thiotrichales	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_723577_3	1278309.KB907104_gene848	1.87e-19	88.6	COG4367@1|root,COG4367@2|Bacteria,1MU6T@1224|Proteobacteria,1RNPG@1236|Gammaproteobacteria,1XIVN@135619|Oceanospirillales	135619|Oceanospirillales	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1453709_1	944546.ABED_1568	7.96e-63	198.0	2BNSM@1|root,32HG6@2|Bacteria,1Q1E8@1224|Proteobacteria,42TDY@68525|delta/epsilon subdivisions,2YPGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40836_1	421072.IO89_12145	5.79e-18	79.3	2E3VP@1|root,32YSV@2|Bacteria,4NV28@976|Bacteroidetes,1I581@117743|Flavobacteriia,3HJ15@358033|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1453711_1	1026882.MAMP_00540	2.38e-65	206.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,4600T@72273|Thiotrichales	72273|Thiotrichales	F	PFAM Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
k59_268418_1	1123228.AUIH01000026_gene3892	6.4e-34	128.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XHWP@135619|Oceanospirillales	135619|Oceanospirillales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_438405_1	1492738.FEM21_10560	1.29e-191	540.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,1HZCS@117743|Flavobacteriia,2NTD9@237|Flavobacterium	976|Bacteroidetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
k59_40866_1	572477.Alvin_0400	3.02e-14	77.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXMA@135613|Chromatiales	135613|Chromatiales	T	Chemotaxis sensory transducer	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
k59_1453756_1	1353528.DT23_14160	1.07e-46	157.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,2XM36@285107|Thioclava	28211|Alphaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1453756_2	1353528.DT23_14165	4.81e-26	107.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria,2XMVC@285107|Thioclava	28211|Alphaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_605762_1	411154.GFO_2318	6.67e-151	435.0	COG2321@1|root,COG2321@2|Bacteria,4NKTG@976|Bacteroidetes,1I06E@117743|Flavobacteriia	976|Bacteroidetes	S	neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_438451_1	1237149.C900_01726	9.35e-105	314.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_1737817_2	929558.SMGD1_0639	4.41e-70	222.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1453770_1	1172190.M947_07150	1.31e-66	221.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1737819_1	929558.SMGD1_0538	5.97e-64	207.0	COG4857@1|root,COG4857@2|Bacteria,1MXBW@1224|Proteobacteria,42UCY@68525|delta/epsilon subdivisions,2YQ64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phosphotransferase enzyme family	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
k59_1737819_2	929558.SMGD1_0537	7.69e-55	180.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
k59_40904_1	1392489.JPOL01000002_gene3373	2.41e-26	110.0	COG1216@1|root,COG1216@2|Bacteria,4NSTS@976|Bacteroidetes,1I0CT@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_605793_1	929558.SMGD1_1942	5.83e-52	173.0	COG2165@1|root,COG2165@2|Bacteria,1NC62@1224|Proteobacteria,42SHI@68525|delta/epsilon subdivisions,2YPH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1285254_1	1144313.PMI10_03509	1.24e-229	651.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_1569283_1	641526.ADIWIN_3456	7.6e-12	70.9	COG1345@1|root,COG3210@1|root,COG3391@1|root,COG1345@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NKG5@976|Bacteroidetes,1IKA4@117743|Flavobacteriia	976|Bacteroidetes	U	Psort location Extracellular, score 9.64	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SASA
k59_1117926_1	1122225.AULQ01000001_gene1613	4.59e-96	303.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_945582_1	572480.Arnit_0309	2.36e-150	426.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2YNUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_945582_2	572480.Arnit_0308	3.72e-114	338.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2YN21@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Fibronectin fibrinogen-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_328441_1	1348657.M622_02335	2.9e-36	130.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,2KXA7@206389|Rhodocyclales	206389|Rhodocyclales	T	Anti sigma-E protein RseA	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
k59_1174595_1	572480.Arnit_2158	9.08e-84	254.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_157279_2	1123228.AUIH01000011_gene2140	1.69e-68	214.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XH4I@135619|Oceanospirillales	135619|Oceanospirillales	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_779277_1	945713.IALB_1465	9.19e-95	295.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_1117948_2	1123277.KB893190_gene4919	9.8e-07	51.2	COG1413@1|root,COG1413@2|Bacteria,4NKJR@976|Bacteroidetes,47NH6@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_43161_1	62928.azo1691	4.33e-60	195.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,2KUN0@206389|Rhodocyclales	206389|Rhodocyclales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_43161_2	497321.C664_00820	1.92e-12	65.9	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,2KVH1@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_891996_1	323850.Shew_3676	1.9e-108	334.0	COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,1S2S3@1236|Gammaproteobacteria,2Q9IF@267890|Shewanellaceae	1236|Gammaproteobacteria	H	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
k59_157292_1	411154.GFO_1526	1.28e-37	132.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,1HWXM@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_157292_2	398720.MED217_08405	2.56e-10	59.3	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1HXRU@117743|Flavobacteriia,2XHZN@283735|Leeuwenhoekiella	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1346692_1	485913.Krac_0568	1.97e-24	106.0	COG0457@1|root,COG0457@2|Bacteria,2G77P@200795|Chloroflexi	200795|Chloroflexi	G	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107
k59_726329_1	90813.JQMT01000001_gene611	2.34e-86	272.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4600X@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_1220032_1	929558.SMGD1_0750	1.35e-79	247.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1220056_1	317025.Tcr_2166	3.76e-90	271.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,45ZXS@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1220056_2	317025.Tcr_2165	5.08e-175	497.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,46017@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1174662_1	323850.Shew_2190	4.27e-92	277.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,2Q93W@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1287920_1	1123518.ARWI01000001_gene154	4.85e-82	247.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,460JP@72273|Thiotrichales	72273|Thiotrichales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_552080_1	62928.azo3571	6.76e-68	221.0	COG0515@1|root,COG0515@2|Bacteria,1R47Q@1224|Proteobacteria,2WGQS@28216|Betaproteobacteria,2KVBN@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_1060566_1	411154.GFO_1809	3.14e-130	400.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1569397_1	1121931.AUHG01000016_gene1125	1.82e-29	111.0	28NAV@1|root,2ZBEH@2|Bacteria,4NJGP@976|Bacteroidetes,1I0G3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_328568_1	1286632.P278_28870	1.65e-176	502.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_383525_2	1123487.KB892846_gene463	1.28e-22	99.0	COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,2VMD1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	malE	-	-	ko:K10108	ko02010,ko02030,map02010,map02030	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	SBP_bac_8
k59_103032_1	1121931.AUHG01000012_gene2502	1.04e-205	584.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_270949_1	572480.Arnit_2256	9.87e-127	397.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_215844_1	929558.SMGD1_2478	8.8e-44	148.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,42KZK@68525|delta/epsilon subdivisions,2YMUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	dehydrogenase	hdhA	-	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_215844_2	929558.SMGD1_2476	1.7e-20	85.9	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K21439	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4,Ank_5
k59_1684219_1	317025.Tcr_1589	6.65e-111	329.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,45ZP1@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1346851_1	1237149.C900_02658	3.72e-39	141.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RJQ@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k59_383586_1	1469557.JSWF01000017_gene2277	1.15e-312	882.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1I0F2@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_64139_1	867902.Ornrh_0524	3.2e-09	59.3	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_64139_2	1168034.FH5T_13235	8.92e-203	566.0	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,2FR92@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
k59_1362310_1	1123518.ARWI01000001_gene561	1.19e-75	232.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,460T5@72273|Thiotrichales	72273|Thiotrichales	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1362310_2	90813.JQMT01000001_gene596	5.4e-12	63.9	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,460NK@72273|Thiotrichales	72273|Thiotrichales	D	Maf-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Maf
k59_233797_1	1380600.AUYN01000006_gene686	8.84e-189	533.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,1HX7U@117743|Flavobacteriia	976|Bacteroidetes	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
k59_233797_2	1178825.ALIH01000013_gene553	6.75e-48	158.0	2DJSG@1|root,32UDQ@2|Bacteria,4NUK1@976|Bacteroidetes,1I4BP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3157
k59_233797_3	745718.JADT01000020_gene307	3.08e-33	115.0	COG3655@1|root,COG3655@2|Bacteria,4NUP7@976|Bacteroidetes,1I506@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
k59_233797_4	641526.ADIWIN_3826	1.79e-13	71.6	2DZKN@1|root,32VD8@2|Bacteria,4NTKQ@976|Bacteroidetes,1I4K2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
k59_1702125_1	945543.VIBR0546_20233	6.1e-113	339.0	2E494@1|root,32Z4W@2|Bacteria,1N7UY@1224|Proteobacteria,1SEFU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1702125_2	1169161.KB897737_gene2354	6.72e-10	63.2	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_289983_1	1121931.AUHG01000011_gene2286	1.65e-77	259.0	COG3209@1|root,COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Reprolysin_4,TSP_3
k59_685837_1	1137281.D778_00180	2.96e-38	141.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_685837_2	391603.FBALC1_04992	1.47e-161	487.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_741613_1	1123518.ARWI01000001_gene400	5.67e-147	438.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_911063_2	1174504.AJTN02000156_gene1088	8.93e-10	58.2	COG0494@1|root,COG0494@2|Bacteria,1V4B2@1239|Firmicutes,4HGZZ@91061|Bacilli,1ZGFM@1386|Bacillus	91061|Bacilli	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_459729_1	1528098.NOVO_02925	2.97e-27	107.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,47EYQ@766|Rickettsiales	766|Rickettsiales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_403076_1	1392490.JHZX01000001_gene2026	3.14e-117	369.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_911066_1	1443665.JACA01000005_gene419	1.57e-187	532.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2YI4W@290174|Aquimarina	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_177375_1	1380600.AUYN01000001_gene2273	1.87e-106	315.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HWQR@117743|Flavobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_403078_1	411154.GFO_2916	8.83e-116	349.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
k59_629031_2	90814.KL370891_gene1023	2.31e-80	243.0	29C1Y@1|root,2ZZ0F@2|Bacteria,1REVX@1224|Proteobacteria,1SDC5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3087
k59_629031_3	1123518.ARWI01000001_gene2201	2.8e-72	240.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,460CR@72273|Thiotrichales	72273|Thiotrichales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_1024530_1	1380600.AUYN01000009_gene2125	1.72e-249	688.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1HXKR@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_1024530_2	1380600.AUYN01000009_gene2126	1.47e-129	389.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_7239_1	1123326.JFBL01000003_gene1953	1.38e-21	90.1	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_7239_2	944547.ABLL_0251	1.42e-74	229.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1362350_1	1122611.KB903961_gene4423	1.22e-08	57.8	COG4447@1|root,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria,4EGDY@85012|Streptosporangiales	201174|Actinobacteria	G	CBD_II	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,fn3
k59_1645853_1	504487.JCM19302_2305	2.9e-29	107.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_177390_1	1565129.JSFF01000007_gene1512	2.53e-31	114.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,2QBII@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
k59_177390_2	1336233.JAEH01000004_gene1449	1.09e-73	229.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,2Q93N@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k59_911089_1	411154.GFO_3319	1.38e-93	291.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_967510_1	1178825.ALIH01000001_gene2535	1.46e-172	493.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_630987_2	944546.ABED_1488	4.23e-40	139.0	COG0340@1|root,COG0340@2|Bacteria,1Q1NZ@1224|Proteobacteria,42RQM@68525|delta/epsilon subdivisions,2YP5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_347857_1	1033802.SSPSH_002793	3.19e-16	81.3	COG1216@1|root,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,1S5S5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_856322_1	1123228.AUIH01000003_gene813	1.16e-97	295.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XH9R@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase	-	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_800685_1	563040.Saut_0231	3.99e-31	111.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2YPXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_800685_2	563040.Saut_0232	2.64e-93	273.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2YNWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_800685_3	929558.SMGD1_0971	1.53e-07	50.1	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2YP4I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_66251_1	318167.Sfri_3655	5.63e-25	97.1	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,2QB2K@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterized protein family, UPF0114	yqhA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_66251_2	1318628.MARLIPOL_06949	6.77e-24	99.8	COG0501@1|root,COG0501@2|Bacteria,1R47C@1224|Proteobacteria,1RPRU@1236|Gammaproteobacteria,46BJ5@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Pilin
k59_1534062_1	1380600.AUYN01000002_gene4	2.33e-106	342.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_179477_1	1168034.FH5T_16490	4.48e-66	213.0	COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes,2FM6R@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1647902_1	504487.JCM19302_3422	2.49e-141	415.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_1647902_2	1121912.AUHD01000001_gene2404	6.9e-51	167.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
k59_461917_1	497321.C664_19076	1.06e-93	280.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2VHXH@28216|Betaproteobacteria,2KVE9@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
k59_688014_1	1121912.AUHD01000001_gene2436	1.06e-124	380.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_179491_1	34007.IT40_21910	4.63e-14	77.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2PVFI@265|Paracoccus	28211|Alphaproteobacteria	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
k59_743581_1	945713.IALB_3067	4.09e-76	240.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1309390_1	572480.Arnit_1169	1.81e-127	368.0	COG2207@1|root,COG2207@2|Bacteria,1QX41@1224|Proteobacteria,42V68@68525|delta/epsilon subdivisions,2YSKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K18954	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
k59_1026625_1	990073.ATHU01000001_gene1787	9.09e-111	324.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2YNF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k59_1647922_1	929558.SMGD1_1033	2.82e-41	142.0	COG4221@1|root,COG4221@2|Bacteria,1QVCA@1224|Proteobacteria,43D38@68525|delta/epsilon subdivisions,2YTFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1647922_2	326298.Suden_2078	1.6e-114	335.0	COG0561@1|root,COG0561@2|Bacteria,1Q5G6@1224|Proteobacteria,42R7D@68525|delta/epsilon subdivisions,2YP2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_1309391_1	929558.SMGD1_1796	1.87e-68	213.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_1081963_1	929558.SMGD1_2169	2.4e-58	189.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2YMDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_1081963_2	929558.SMGD1_2168	3.44e-117	338.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2YNZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_1081963_3	1172190.M947_09895	2.38e-22	89.0	COG1539@1|root,COG1539@2|Bacteria,1RHII@1224|Proteobacteria,42V1R@68525|delta/epsilon subdivisions,2YQ8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydroneopterin aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_1026627_1	1348657.M622_08680	8.24e-11	61.6	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,2KUSN@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1026627_2	1123518.ARWI01000001_gene219	1.43e-80	249.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,4607C@72273|Thiotrichales	72273|Thiotrichales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1138753_1	1175654.A0A0S0N2K6_9CAUD	2.85e-80	270.0	4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses  no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae	10699|Siphoviridae	S	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1534117_1	1123514.KB905899_gene1784	1.64e-209	590.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,45ZUA@72273|Thiotrichales	72273|Thiotrichales	M	gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_1647958_1	504487.JCM19302_3265	4.59e-124	389.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1309414_1	1406840.Q763_09740	9.9e-128	365.0	COG0497@1|root,COG0497@2|Bacteria,4NMQC@976|Bacteroidetes,1IMS8@117743|Flavobacteriia,2NUD4@237|Flavobacterium	976|Bacteroidetes	L	Conjugal transfer protein TraI	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1309414_2	1406840.Q763_09735	0.0	1364.0	COG3451@1|root,COG3451@2|Bacteria,4NER7@976|Bacteroidetes,1HWN6@117743|Flavobacteriia,2NTNA@237|Flavobacterium	976|Bacteroidetes	U	Conjugal transfer protein TraG	-	-	-	-	-	-	-	-	-	-	-	-	CagE_TrbE_VirB,DUF3875
k59_631089_1	1123518.ARWI01000001_gene89	2.81e-81	251.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,45ZZ9@72273|Thiotrichales	72273|Thiotrichales	E	Ferric iron ABC transporter, ATP-binding protein	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_1193217_1	472759.Nhal_1639	4.6e-62	213.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_122379_1	1182590.BN5_00444	4.34e-40	140.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,1YI0H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_122379_2	1123366.TH3_20688	1.83e-49	166.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TUIC@28211|Alphaproteobacteria,2JQGG@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
k59_1534126_1	1123514.KB905899_gene1149	5.83e-123	363.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,45ZU3@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_1138769_1	504487.JCM19302_4214	6.66e-289	790.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1HXCC@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_1138769_2	1178825.ALIH01000003_gene2232	1.8e-82	258.0	COG3281@1|root,COG3281@2|Bacteria,4PMAP@976|Bacteroidetes,1HZME@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH
k59_405224_2	1123033.ARNF01000084_gene1599	1.26e-56	194.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,3NIII@468|Moraxellaceae	1236|Gammaproteobacteria	O	Magnesium chelatase, subunit ChlI	comM	GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_347959_1	1416760.AYMS01000031_gene2443	4.89e-17	76.3	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1I1GF@117743|Flavobacteriia,47I89@76831|Myroides	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_347959_2	1416760.AYMS01000031_gene2444	1.84e-107	329.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,47HA0@76831|Myroides	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1251861_1	504487.JCM19302_1086	6.41e-32	124.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,1HZQ0@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1082024_1	1197477.IA57_07810	3.57e-71	227.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_1309447_1	1121875.KB907549_gene1903	3.4e-118	357.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1HYH5@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_1138789_1	991905.SL003B_3096	5.89e-153	459.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,4BR82@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1478099_1	225849.swp_0595	2.8e-65	201.0	2EDGK@1|root,337CT@2|Bacteria,1NFEP@1224|Proteobacteria,1SENV@1236|Gammaproteobacteria,2QCDF@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1647998_1	411154.GFO_0158	1.3e-45	167.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1251871_1	387093.SUN_0733	2.01e-164	473.0	COG1075@1|root,COG1075@2|Bacteria,1NMH0@1224|Proteobacteria,42MAK@68525|delta/epsilon subdivisions,2YNFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
k59_179581_1	631362.Thi970DRAFT_02485	2.37e-76	253.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,1RYBW@1236|Gammaproteobacteria,1X0HK@135613|Chromatiales	135613|Chromatiales	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1591813_1	90813.JQMT01000001_gene1760	7e-33	115.0	2E4HY@1|root,32ZD1@2|Bacteria,1N74N@1224|Proteobacteria,1SCRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Late competence development protein ComFB	-	-	-	-	-	-	-	-	-	-	-	-	ComFB
k59_1591813_2	1123518.ARWI01000001_gene1978	3.52e-227	632.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4601Y@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the GARS family	purD	-	6.3.2.6,6.3.4.13	ko:K01945,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N,SAICAR_synt
k59_78713_2	411154.GFO_2137	2.52e-145	416.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HXME@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_1604213_1	1499686.BN1079_01943	4.58e-71	233.0	COG0438@1|root,COG2148@1|root,COG0438@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	epsL	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k59_1149887_1	1278309.KB907102_gene32	1.83e-59	197.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria,1XJMI@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
k59_1201928_1	572480.Arnit_2424	4.2e-131	380.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2YMY4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
k59_813250_1	888059.HMPREF9071_2175	2.17e-11	69.7	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia,1EQ6A@1016|Capnocytophaga	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
k59_1604239_1	1123518.ARWI01000001_gene1262	3.88e-155	445.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,461KA@72273|Thiotrichales	72273|Thiotrichales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1490525_1	323850.Shew_0348	5.89e-86	271.0	COG0484@1|root,COG0484@2|Bacteria,1MV51@1224|Proteobacteria,1RZ47@1236|Gammaproteobacteria,2Q9EX@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0055114,GO:0070813,GO:0070814,GO:0097159,GO:1901363,GO:1903136	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
k59_586114_1	1123518.ARWI01000001_gene670	2.06e-172	508.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,45ZRH@72273|Thiotrichales	72273|Thiotrichales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_586114_2	90814.KL370891_gene638	9.18e-75	225.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,460PH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_191588_1	411154.GFO_2545	2.83e-59	189.0	COG1940@1|root,COG1940@2|Bacteria,4NFNR@976|Bacteroidetes,1HZGY@117743|Flavobacteriia	976|Bacteroidetes	GK	Transcriptional regulator sugar kinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_1490528_1	945713.IALB_0262	2.74e-05	45.4	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1716520_2	709032.Sulku_0497	2.69e-41	136.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42VEW@68525|delta/epsilon subdivisions,2YQ7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RNA-binding protein	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_1716520_3	563040.Saut_1757	7.06e-44	147.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_248214_1	929558.SMGD1_2607	6.07e-125	370.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_1773282_2	1484460.JSWG01000008_gene1928	1.34e-85	265.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
k59_702714_1	945713.IALB_0215	4.41e-71	218.0	COG2818@1|root,COG2818@2|Bacteria	2|Bacteria	L	DNA-3-methyladenine glycosylase activity	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_1434707_1	90814.KL370891_gene260	2.47e-58	190.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,460XI@72273|Thiotrichales	72273|Thiotrichales	L	TatD family	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_1434707_2	1123518.ARWI01000001_gene1013	2.62e-77	231.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,460U0@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_1434707_3	1123518.ARWI01000001_gene1014	1.03e-202	565.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,4603Q@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1434707_4	317025.Tcr_0318	5.42e-131	373.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,4601G@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_1434707_5	1123518.ARWI01000001_gene1016	8.93e-84	248.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,460IQ@72273|Thiotrichales	72273|Thiotrichales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1718272_1	211586.SO_2978	5.64e-47	164.0	COG0276@1|root,COG0582@1|root,COG0276@2|Bacteria,COG0582@2|Bacteria,1RBN3@1224|Proteobacteria,1S2R6@1236|Gammaproteobacteria,2QCEI@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_870576_1	876044.IMCC3088_1256	1.54e-07	54.3	COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
k59_870576_2	317025.Tcr_1793	1.45e-85	270.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,4625V@72273|Thiotrichales	72273|Thiotrichales	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_815218_1	240015.ACP_1342	6.7e-19	91.3	COG0841@1|root,COG0841@2|Bacteria,3Y2TW@57723|Acidobacteria,2JIH3@204432|Acidobacteriia	204432|Acidobacteriia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1151814_1	62928.azo3215	1.11e-98	310.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_531861_2	929558.SMGD1_0555	4.27e-29	119.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2YN0J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_306090_1	153721.MYP_4401	4.19e-97	291.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,47MJV@768503|Cytophagia	976|Bacteroidetes	S	Nitronate monooxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
k59_1606322_1	411154.GFO_1106	1.96e-181	526.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_475986_1	1123228.AUIH01000011_gene2068	2.44e-40	139.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XHWY@135619|Oceanospirillales	135619|Oceanospirillales	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_475986_2	1500893.JQNB01000001_gene1101	1.38e-10	60.8	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1X3TD@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_1151852_1	411154.GFO_0020	5.42e-105	314.0	COG2223@1|root,COG2223@2|Bacteria,4PMRK@976|Bacteroidetes,1IJXD@117743|Flavobacteriia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_22289_1	864051.BurJ1DRAFT_3166	1.88e-25	104.0	COG0438@1|root,COG0438@2|Bacteria,1R2WM@1224|Proteobacteria,2VKPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_22289_2	76114.ebA4269	1.83e-40	143.0	COG1305@1|root,COG1305@2|Bacteria,1RGH2@1224|Proteobacteria,2VSA1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1265716_1	563040.Saut_0706	3.87e-96	294.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_1265716_2	929558.SMGD1_2185	9.38e-28	108.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1095512_1	323850.Shew_0383	1.07e-40	144.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,2Q8H1@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM malic enzyme domain protein	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_1095512_2	1565129.JSFF01000009_gene1812	2.18e-46	155.0	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1SG90@1236|Gammaproteobacteria,2QAZ2@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM nuclease (SNase domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	SNase
k59_870641_1	1121931.AUHG01000010_gene487	4.7e-133	399.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_250240_1	1565129.JSFF01000011_gene1970	1.43e-145	420.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,2QAVC@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM PfkB domain protein	pfkB	-	2.7.1.15,2.7.1.4,2.7.1.73	ko:K00847,ko:K00852,ko:K00892	ko00030,ko00051,ko00230,ko00500,ko00520,ko01100,map00030,map00051,map00230,map00500,map00520,map01100	-	R00760,R00867,R01051,R01131,R01228,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_476002_1	1380600.AUYN01000001_gene2405	2.62e-88	269.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia	976|Bacteroidetes	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_476002_2	1178825.ALIH01000002_gene941	1.03e-26	99.8	2DS5M@1|root,33END@2|Bacteria	2|Bacteria	S	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
k59_476002_3	1178825.ALIH01000002_gene940	6.5e-73	225.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_476002_4	1380600.AUYN01000001_gene2402	1.35e-127	367.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_193572_1	1172190.M947_05350	1.88e-82	245.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2YP9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_193572_2	563040.Saut_2106	2.97e-11	62.8	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_1323929_1	1454004.AW11_01575	1.31e-110	327.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,1KQ7P@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_418989_1	1380600.AUYN01000006_gene285	5.06e-88	269.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_870648_1	411154.GFO_0138	5.6e-126	383.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_926464_1	869213.JCM21142_104067	9.69e-75	259.0	COG0553@1|root,COG1203@1|root,COG0553@2|Bacteria,COG1203@2|Bacteria	2|Bacteria	L	DNA/RNA hybrid annealing activity	-	-	3.6.4.12	ko:K03657,ko:K07012	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03400	-	-	-	AAA_34,Helicase_C,Helicase_C_4,ResIII,UvrD-helicase,UvrD_C_2
k59_1547509_1	1038869.AXAN01000031_gene542	3.13e-51	184.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1K1BU@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
k59_1661998_1	1286632.P278_06900	1.72e-61	198.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_1661998_2	865937.Gilli_3113	2.71e-240	674.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1HZDM@117743|Flavobacteriia,2P5K4@244698|Gillisia	976|Bacteroidetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_1662000_1	313603.FB2170_03800	3.76e-119	358.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2PIK7@252356|Maribacter	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_815327_1	1353528.DT23_16245	9.57e-146	416.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,2XMVD@285107|Thioclava	28211|Alphaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_135736_1	929558.SMGD1_1792	3.64e-51	170.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2YMX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	nikY	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_135736_2	929558.SMGD1_1793	1.02e-68	218.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_1718386_1	1046627.BZARG_1270	7.2e-149	436.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_1492658_1	572480.Arnit_2888	3.67e-109	321.0	28M05@1|root,2ZB16@2|Bacteria,1QVZ0@1224|Proteobacteria,43CB8@68525|delta/epsilon subdivisions,2YTAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_419042_1	1121931.AUHG01000011_gene2257	1.34e-156	450.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_22364_1	1232410.KI421412_gene382	1.69e-66	216.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,43T6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_419044_2	1046627.BZARG_1815	1.96e-07	51.2	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1HX80@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_531981_1	563040.Saut_1110	6.42e-118	348.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2YMKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_80605_1	90814.KL370891_gene550	3.96e-122	352.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,460D2@72273|Thiotrichales	72273|Thiotrichales	T	TIGRFAM phosphate regulon transcriptional regulatory protein PhoB	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_80605_2	1123514.KB905899_gene1564	2.48e-50	172.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,460G5@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
k59_1775442_1	1353528.DT23_07065	6e-100	316.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2XMWJ@285107|Thioclava	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	MA20_16805	-	-	ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
k59_1265799_1	717231.Flexsi_1016	9.78e-127	370.0	COG1638@1|root,COG1638@2|Bacteria,2GFAE@200930|Deferribacteres	200930|Deferribacteres	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_361423_1	1270193.JARP01000006_gene1744	3.6e-09	56.6	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HXEA@117743|Flavobacteriia,2NTF3@237|Flavobacterium	976|Bacteroidetes	G	Pfam Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
k59_361423_2	1380600.AUYN01000001_gene2651	4.63e-94	296.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_815380_1	326298.Suden_0840	3.08e-19	82.4	COG1580@1|root,COG1580@2|Bacteria,1NBUX@1224|Proteobacteria,42RSV@68525|delta/epsilon subdivisions,2YPAW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_815380_2	929558.SMGD1_0372	4.45e-70	217.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2YMNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_645266_1	90813.JQMT01000001_gene1359	3.4e-134	414.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_135799_1	1178825.ALIH01000009_gene1330	8.8e-57	187.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_361440_1	317025.Tcr_2024	5.62e-151	446.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,PAS_4
k59_1151991_1	330214.NIDE0032	5.36e-21	95.5	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1434901_1	865937.Gilli_2225	5.2e-55	199.0	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia,2P62Z@244698|Gillisia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1434903_1	1124780.ANNU01000035_gene270	3.11e-59	197.0	COG0438@1|root,COG0438@2|Bacteria,4NIV3@976|Bacteroidetes,47P66@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_532036_1	1123514.KB905902_gene268	8.4e-11	59.3	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,1SCEN@1236|Gammaproteobacteria,461BY@72273|Thiotrichales	72273|Thiotrichales	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_532036_2	1123518.ARWI01000001_gene1435	2.48e-76	234.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_757078_1	1121931.AUHG01000011_gene2136	2.56e-46	160.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_1662097_1	1123228.AUIH01000004_gene1014	2.46e-51	166.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1XKHN@135619|Oceanospirillales	135619|Oceanospirillales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_979149_1	1121912.AUHD01000014_gene1080	4.62e-223	644.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_1434913_1	411154.GFO_2889	2.87e-142	406.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_22436_1	1565314.OA34_05910	1.37e-49	163.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2YMUD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_22436_2	1537917.JU82_10425	7.13e-05	42.4	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,42VYX@68525|delta/epsilon subdivisions,2YSCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pathogenicity locus	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
k59_193716_1	1469557.JSWF01000029_gene3381	1.71e-57	190.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia	976|Bacteroidetes	O	assembly protein, SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_193716_2	504487.JCM19302_3841	1.52e-161	454.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia	976|Bacteroidetes	O	Part of SUF system involved in inserting iron-sulfur clusters into proteins	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_1054959_1	643867.Ftrac_2936	3.74e-66	214.0	COG4192@1|root,COG4192@2|Bacteria,4NFY7@976|Bacteroidetes,47MMQ@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
k59_435776_1	1122201.AUAZ01000002_gene888	1.26e-27	116.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Protoglobin,Response_reg
k59_1170901_3	983544.Lacal_1417	3.42e-34	121.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1I40T@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k59_40072_1	1237149.C900_01054	1.5e-21	85.1	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_40072_2	1237149.C900_01053	5.04e-108	312.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,47M7G@768503|Cytophagia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_888892_1	998674.ATTE01000001_gene675	8.5e-57	197.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_267618_2	314282.PCNPT3_08780	1.99e-10	57.4	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,2QIFU@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_267618_3	1122599.AUGR01000021_gene3243	2.18e-20	90.5	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHFD@135619|Oceanospirillales	135619|Oceanospirillales	P	P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1565945_1	1537915.JU57_02550	4.01e-10	63.2	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2YN86@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	cbrR	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1565945_2	1123514.KB905899_gene1943	9.05e-72	226.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_997042_1	387093.SUN_1314	3.99e-43	160.0	COG0732@1|root,COG0827@1|root,COG1002@1|root,COG0732@2|Bacteria,COG0827@2|Bacteria,COG1002@2|Bacteria,1MVG5@1224|Proteobacteria,42PJ2@68525|delta/epsilon subdivisions,2YN2S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	LV	TaqI-like C-terminal specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
k59_1623992_1	1123518.ARWI01000001_gene1951	5.08e-162	479.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,45ZYC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_604786_1	32024.JMTI01000035_gene890	1.21e-50	167.0	COG0529@1|root,COG0529@2|Bacteria,1N2Z8@1224|Proteobacteria,42SD8@68525|delta/epsilon subdivisions,2YTS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Adenylylsulfate kinase	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k59_99230_1	572480.Arnit_2094	4.51e-77	233.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,42SHJ@68525|delta/epsilon subdivisions,2YPQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_8
k59_494171_1	1121931.AUHG01000017_gene1512	2.18e-05	52.8	28JC9@1|root,2Z96Z@2|Bacteria,4NH48@976|Bacteroidetes,1HYRM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_494171_2	411154.GFO_1789	5.87e-91	281.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1HYFW@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_1736838_1	1121931.AUHG01000020_gene3127	2.01e-19	84.0	2DU60@1|root,33P2N@2|Bacteria,4NYCI@976|Bacteroidetes,1IA7T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1736838_2	1121931.AUHG01000020_gene3128	6.58e-87	264.0	COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,1I0DK@117743|Flavobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4
k59_604811_1	1172190.M947_03445	4.07e-82	253.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_379768_2	526222.Desal_3629	2.84e-15	77.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,42PP5@68525|delta/epsilon subdivisions,2WMQR@28221|Deltaproteobacteria,2M8D9@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k59_1056846_1	326298.Suden_0354	1.14e-81	270.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_379773_1	411154.GFO_3191	6.99e-98	305.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_1511686_1	1046627.BZARG_1463	2.29e-136	395.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
k59_1680282_1	458817.Shal_1197	3.66e-59	186.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,2Q9YM@267890|Shewanellaceae	1236|Gammaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k59_1565987_1	1178825.ALIH01000003_gene1994	8.58e-105	331.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_1624029_1	1254432.SCE1572_06460	1.02e-51	183.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_722793_1	1353528.DT23_15835	1.23e-114	335.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2XMA7@285107|Thioclava	28211|Alphaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_212154_1	143224.JQMD01000002_gene1817	1.05e-41	151.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes,1HXU6@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
k59_379793_1	317025.Tcr_0414	1.14e-235	672.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,45ZTI@72273|Thiotrichales	72273|Thiotrichales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1056879_1	1123514.KB905902_gene231	2.63e-61	198.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_379808_1	1150621.SMUL_1223	1.12e-18	86.7	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02030,ko:K07679	ko02020,ko05133,map02020,map05133	M00236,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
k59_379808_2	709032.Sulku_1308	4.44e-77	237.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212173_1	1565129.JSFF01000003_gene2205	1.91e-73	233.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,2Q8RV@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM multi antimicrobial extrusion protein MatE	mdtK	GO:0000302,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0006857,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0015238,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0033554,GO:0034599,GO:0034614,GO:0035442,GO:0035672,GO:0035673,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042938,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:1901700,GO:1901701,GO:1904680	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_775425_2	563040.Saut_0046	1.36e-71	224.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2YMFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1056913_1	411902.CLOBOL_05870	4.47e-16	72.8	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,220U1@1506553|Lachnoclostridium	186801|Clostridia	K	adenine-specific DNA methyltransferase K06223	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_40181_1	55207.KP22_10240	1.54e-72	252.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1MQB1@122277|Pectobacterium	1236|Gammaproteobacteria	Q	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KR,Methyltransf_12,PP-binding,TauD,Thioesterase
k59_99326_1	318167.Sfri_0452	5.2e-79	261.0	COG0210@1|root,COG0551@1|root,COG0210@2|Bacteria,COG0551@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,2QA64@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DNA topoisomerase, type IA, zn finger domain protein	helD	-	3.6.4.12	ko:K03658	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_IV_N,UvrD-helicase,UvrD_C,zf-C4_Topoisom
k59_1736926_1	1408433.JHXV01000016_gene1828	2.39e-53	189.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia,2PA94@246874|Cryomorphaceae	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_722838_1	572480.Arnit_0691	6.12e-80	252.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,PRD,Response_reg
k59_722838_2	63577.G9NEC0	6.53e-08	54.7	COG0652@1|root,KOG0883@2759|Eukaryota,38E53@33154|Opisthokonta,3NUAM@4751|Fungi,3QKM8@4890|Ascomycota,217N3@147550|Sordariomycetes,3TFS4@5125|Hypocreales,3TXCF@5129|Hypocreaceae	4751|Fungi	O	U-box domain	cyp8	GO:0000209,GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0019787,GO:0032446,GO:0034450,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0061630,GO:0061659,GO:0070647,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K10598	ko04120,map04120	-	-	-	ko00000,ko00001,ko01000,ko03041,ko03110,ko04121	-	-	-	Pro_isomerase,Rtf2,U-box
k59_1056929_1	1123228.AUIH01000018_gene3533	1.12e-101	303.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XMXW@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k59_1171077_2	945550.VISI1226_14323	1.1e-09	62.0	COG2304@1|root,COG2304@2|Bacteria,1QJKX@1224|Proteobacteria,1THMJ@1236|Gammaproteobacteria,1XWQ6@135623|Vibrionales	135623|Vibrionales	Q	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin
k59_40201_1	929558.SMGD1_1614	1.86e-108	318.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2YN3F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_40201_2	929558.SMGD1_1613	2.22e-66	209.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2YMIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_325016_2	1123518.ARWI01000001_gene999	8.54e-37	138.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,460Y5@72273|Thiotrichales	72273|Thiotrichales	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_664198_1	504487.JCM19302_647	1.2e-62	201.0	29XM4@1|root,30JCC@2|Bacteria,4P9A6@976|Bacteroidetes,1IBM0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_212231_1	1236541.BALL01000037_gene3671	5.78e-32	120.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,2Q8X5@267890|Shewanellaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_2953	GCV_T,GCV_T_C
k59_212231_2	318167.Sfri_3150	1.31e-67	206.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,2QBKB@267890|Shewanellaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iE2348C_1286.E2348C_3156,iPC815.YPO0906	GCV_H
k59_1114398_1	929558.SMGD1_0709	3.83e-185	530.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_889052_1	62928.azo0304	1.03e-204	568.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2VHQZ@28216|Betaproteobacteria,2KUW7@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenylacetate-CoA oxygenase subunit PaaA	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_99376_1	425104.Ssed_4405	6.97e-17	75.1	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2QC9H@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
k59_99376_2	323850.Shew_0085	8.4e-20	89.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAQI@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k59_154232_1	398527.Bphyt_6000	3.32e-32	128.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1JZWE@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	Cache type 2 domain protein	-	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_1736987_1	1288963.ADIS_3721	7.97e-31	125.0	COG1352@1|root,COG2201@1|root,COG2202@1|root,COG3829@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,47XZS@768503|Cytophagia	976|Bacteroidetes	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
k59_548625_1	929558.SMGD1_0670	1.89e-69	223.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2YMA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_604958_1	1380600.AUYN01000009_gene1928	5.05e-39	139.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_604958_2	1121887.AUDK01000030_gene2293	1.62e-18	80.9	2CFVU@1|root,3373K@2|Bacteria,4NY6U@976|Bacteroidetes,1ID3F@117743|Flavobacteriia,2NX5E@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_604958_4	398720.MED217_05207	7.37e-68	210.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1I1YP@117743|Flavobacteriia,2XJG9@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_604958_5	1121912.AUHD01000009_gene3747	2.39e-126	367.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_494345_1	1197477.IA57_12535	1.28e-161	465.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_889081_2	1408164.MOLA814_02439	6.48e-26	102.0	COG0450@1|root,COG0450@2|Bacteria,1QWIV@1224|Proteobacteria,2WHWS@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_942504_1	983544.Lacal_2235	2.52e-82	253.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k59_942504_2	764291.STRUR_2143	2.61e-37	142.0	COG3677@1|root,COG3677@2|Bacteria,1V4D1@1239|Firmicutes,4HREI@91061|Bacilli	91061|Bacilli	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
k59_942504_5	1353276.JADR01000001_gene433	9.39e-58	192.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1HY8U@117743|Flavobacteriia	976|Bacteroidetes	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1794262_1	1353528.DT23_17695	6.9e-122	374.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2XMF0@285107|Thioclava	28211|Alphaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_1284488_1	1172190.M947_07495	1.43e-118	362.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YNHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1284488_2	929558.SMGD1_1003	2.83e-29	114.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2YMJJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	malic enzyme	mez	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_1737021_2	1168281.I3PUY3_9CAUD	2.03e-33	120.0	4QEFN@10239|Viruses,4QZ2Y@35237|dsDNA viruses  no RNA stage,4QTT5@28883|Caudovirales,4QNIQ@10744|Podoviridae	10744|Podoviridae	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_437708_1	1165841.SULAR_02863	5.5e-35	123.0	2DMVP@1|root,32TYU@2|Bacteria,1MZ9J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_437708_2	1397527.Q670_14170	3.01e-54	173.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,1S60C@1236|Gammaproteobacteria,1XKQ9@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_548652_1	1168065.DOK_07049	3.43e-13	70.9	COG3081@1|root,COG3081@2|Bacteria,1R957@1224|Proteobacteria,1S3G0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
k59_379926_1	944547.ABLL_2322	7.45e-62	205.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_379926_2	572480.Arnit_1285	1.15e-38	140.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2YNQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_494379_1	211586.SO_0867	4.42e-90	286.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,2Q9PE@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
k59_437750_1	709032.Sulku_1094	8.35e-49	159.0	COG2768@1|root,COG2768@2|Bacteria,1R1K0@1224|Proteobacteria,43DAC@68525|delta/epsilon subdivisions,2YTHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Fer4_9
k59_437750_2	572480.Arnit_0075	2.12e-25	101.0	COG0694@1|root,COG0790@1|root,COG0694@2|Bacteria,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	nifU	-	-	ko:K07126,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N,Sel1
k59_548698_1	572480.Arnit_1552	4.26e-156	453.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1566164_1	1137281.D778_01839	7.67e-171	490.0	COG0664@1|root,COG0664@2|Bacteria,4NEWA@976|Bacteroidetes,1HWPV@117743|Flavobacteriia	976|Bacteroidetes	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_997306_2	1123514.KB905903_gene366	8.21e-168	491.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,461T0@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_215212_1	572480.Arnit_2501	1.78e-118	355.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_725847_1	865937.Gilli_1339	6.48e-10	58.5	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1HWNZ@117743|Flavobacteriia,2P5UE@244698|Gillisia	976|Bacteroidetes	J	Polyribonucleotide nucleotidyltransferase, RNA binding domain	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1568928_1	398720.MED217_14945	6.47e-159	455.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanH	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,CW_binding_1,F5_F8_type_C,NPCBM_assoc
k59_1000262_1	358220.C380_09235	4.33e-47	173.0	COG3452@1|root,COG5001@1|root,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
k59_618622_1	1178825.ALIH01000002_gene1088	1.39e-42	155.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1231285_1	717774.Marme_0544	1.63e-33	121.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,1T1S0@1236|Gammaproteobacteria,1XKQ3@135619|Oceanospirillales	135619|Oceanospirillales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_1231285_2	641526.ADIWIN_0798	1.06e-57	191.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_902714_1	929558.SMGD1_2185	9.9e-99	294.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2YMK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1070942_1	1168067.JAGP01000001_gene888	6.83e-218	617.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales	72273|Thiotrichales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_1185689_2	1347342.BN863_19800	2.52e-57	191.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_902732_1	1123517.JOMR01000001_gene271	5.73e-32	129.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,463V7@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_902732_2	1123373.ATXI01000012_gene937	6.97e-07	54.3	COG3221@1|root,COG3221@2|Bacteria,2GHS1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
k59_618663_1	1355374.JARU01000005_gene1838	7.61e-106	338.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2YRDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Putative exonuclease SbcCD, C subunit	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_1231328_1	247490.KSU1_C0377	5.41e-08	53.5	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	Beta_helix,DUF1565,Laminin_G_3,Metallophos
k59_1231328_2	243231.GSU0204	2.76e-09	57.0	COG1032@1|root,COG1032@2|Bacteria,1R92G@1224|Proteobacteria,42RM5@68525|delta/epsilon subdivisions,2WNP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_53287_1	319236.JCM19294_1785	3.27e-68	211.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,1I172@117743|Flavobacteriia,3HK7Q@363408|Nonlabens	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_53287_2	742766.HMPREF9455_03725	4.48e-23	97.1	COG0394@1|root,COG1247@1|root,COG0394@2|Bacteria,COG1247@2|Bacteria,4NPIE@976|Bacteroidetes,2FSNY@200643|Bacteroidia,22XU3@171551|Porphyromonadaceae	976|Bacteroidetes	M	FR47-like protein	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
k59_790629_1	1178825.ALIH01000006_gene1444	1.77e-144	409.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1HXT0@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1579597_1	1121931.AUHG01000011_gene1906	2.67e-73	223.0	COG3210@1|root,COG3210@2|Bacteria,4NUIX@976|Bacteroidetes,1I5AC@117743|Flavobacteriia	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1128922_1	1123278.KB893574_gene6153	3.94e-25	109.0	COG0702@1|root,COG0702@2|Bacteria,4NEDB@976|Bacteroidetes,47K1A@768503|Cytophagia	976|Bacteroidetes	GM	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1128922_2	1463917.JODC01000010_gene4092	8.43e-95	285.0	COG5426@1|root,COG5426@2|Bacteria,2GNA5@201174|Actinobacteria	201174|Actinobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
k59_1128922_3	435591.BDI_1657	1.03e-109	327.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,2FPM3@200643|Bacteroidia,22XY8@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1128922_4	2002.JOEQ01000022_gene6942	2.85e-09	62.8	COG4222@1|root,COG4222@2|Bacteria,2GNHR@201174|Actinobacteria,4EGV9@85012|Streptosporangiales	201174|Actinobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_1466920_1	1298593.TOL_0749	4.07e-48	160.0	COG0664@1|root,COG0664@2|Bacteria,1RA0I@1224|Proteobacteria,1S23G@1236|Gammaproteobacteria,1XMDV@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_1298971_1	1123518.ARWI01000001_gene1773	8.25e-117	380.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462CG@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM
k59_53305_1	1123518.ARWI01000001_gene269	5.94e-71	240.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,4614F@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_9
k59_451324_1	717773.Thicy_0387	7.05e-23	97.4	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,4600B@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_451324_2	317025.Tcr_2151	2.56e-201	575.0	COG0004@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2199@2|Bacteria,1NR9F@1224|Proteobacteria,1T3XB@1236|Gammaproteobacteria,463UW@72273|Thiotrichales	72273|Thiotrichales	U	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1632799_1	1121931.AUHG01000012_gene2698	7.93e-30	112.0	2AISX@1|root,3199U@2|Bacteria,4NQ7A@976|Bacteroidetes,1I3B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_902823_1	1121931.AUHG01000011_gene1988	6.24e-159	479.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1185787_1	869213.JCM21142_41980	3.57e-51	182.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes	976|Bacteroidetes	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_845321_1	637905.SVI_3863	3.02e-26	104.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,2Q9HJ@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM aminotransferase class V	pucG	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_845321_2	225849.swp_0363	1.1e-13	69.7	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,2Q9P5@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2699	PALP,Thr_dehydrat_C
k59_53335_1	323850.Shew_1829	3.61e-89	263.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,2QARB@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Peptidase M15A	ycbK	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
k59_451353_1	1121035.AUCH01000012_gene3022	2.29e-21	98.2	COG1352@1|root,COG5001@1|root,COG1352@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVWQ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4
k59_902854_1	563040.Saut_0978	9.1e-73	239.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YR6J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_902854_2	709032.Sulku_0968	3.02e-05	45.4	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,4304D@68525|delta/epsilon subdivisions,2YRUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	COGs COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_394721_1	1123514.KB905902_gene236	7.86e-36	142.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,460JF@72273|Thiotrichales	72273|Thiotrichales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_394721_2	1123518.ARWI01000001_gene1403	3.32e-70	231.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,45ZUR@72273|Thiotrichales	72273|Thiotrichales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_451375_1	411154.GFO_2268	1.92e-69	214.0	COG2062@1|root,COG2062@2|Bacteria,4PMDV@976|Bacteroidetes,1IJZ0@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k59_1408545_2	404380.Gbem_1266	1.88e-25	104.0	COG1555@1|root,COG1555@2|Bacteria,1Q1N7@1224|Proteobacteria,431JQ@68525|delta/epsilon subdivisions,2WT0M@28221|Deltaproteobacteria,43VKM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k59_1012134_1	62928.azo3972	1.12e-121	348.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria,2KVTJ@206389|Rhodocyclales	206389|Rhodocyclales	Q	methionine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	MetW
k59_279905_1	1177179.A11A3_06963	2.08e-12	72.8	COG4585@1|root,COG4585@2|Bacteria,1QSUV@1224|Proteobacteria,1RR41@1236|Gammaproteobacteria,1XNEI@135619|Oceanospirillales	135619|Oceanospirillales	T	COG4585 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53378_1	211586.SO_4267	8.41e-142	433.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,2QARI@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DEAD DEAH box helicase domain protein	hsdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII
k59_1299090_1	745718.JADT01000001_gene2050	4.33e-212	598.0	COG3344@1|root,COG3344@2|Bacteria,4NJS7@976|Bacteroidetes,1HYXK@117743|Flavobacteriia	976|Bacteroidetes	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_1071085_1	1484460.JSWG01000009_gene387	5.45e-258	709.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
k59_1071085_2	1380600.AUYN01000006_gene652	1.38e-98	292.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_902930_1	1123518.ARWI01000001_gene2204	1.06e-39	153.0	COG0840@1|root,COG0840@2|Bacteria,1NRAC@1224|Proteobacteria,1SKST@1236|Gammaproteobacteria,4624F@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_394795_1	1121007.AUML01000014_gene2879	7.63e-53	170.0	COG1180@1|root,COG1180@2|Bacteria,4NR4M@976|Bacteroidetes,1I1XG@117743|Flavobacteriia,2YIW5@290174|Aquimarina	976|Bacteroidetes	O	4Fe-4S single cluster domain	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12
k59_394795_2	1121007.AUML01000014_gene2878	2.62e-18	83.6	COG1328@1|root,COG1328@2|Bacteria,4NFVE@976|Bacteroidetes,1I51J@117743|Flavobacteriia,2YJ96@290174|Aquimarina	976|Bacteroidetes	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_902934_1	1172190.M947_03035	4.62e-128	384.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1632895_1	572480.Arnit_0827	9.27e-119	362.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_451454_2	946077.W5A_06088	1.65e-15	77.8	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
k59_618889_1	411154.GFO_2626	2.04e-145	412.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1HXX5@117743|Flavobacteriia	976|Bacteroidetes	T	response regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_1185928_1	265072.Mfla_0182	2.15e-64	221.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KKR4@206350|Nitrosomonadales	206350|Nitrosomonadales	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_7
k59_618893_1	411154.GFO_0222	3.65e-130	380.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
k59_1129110_1	1121007.AUML01000014_gene2878	2.67e-131	389.0	COG1328@1|root,COG1328@2|Bacteria,4NFVE@976|Bacteroidetes,1I51J@117743|Flavobacteriia,2YJ96@290174|Aquimarina	976|Bacteroidetes	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_394843_1	572480.Arnit_2785	6.95e-94	290.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
k59_394843_2	1249480.B649_05180	5.71e-07	52.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria	1224|Proteobacteria	CO	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
k59_1231548_2	1123518.ARWI01000001_gene613	9.16e-208	578.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,45ZZG@72273|Thiotrichales	72273|Thiotrichales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_1231548_3	90814.KL370891_gene697	3.7e-158	460.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,460A5@72273|Thiotrichales	72273|Thiotrichales	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_563087_1	1123514.KB905899_gene1925	4.62e-124	367.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,46000@72273|Thiotrichales	72273|Thiotrichales	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_845479_2	90814.KL370892_gene2239	7.86e-98	293.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S5VC@1236|Gammaproteobacteria,460X1@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_1299173_1	411154.GFO_1082	2.04e-115	336.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,1HWNQ@117743|Flavobacteriia	976|Bacteroidetes	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_1071160_1	945713.IALB_2949	7.14e-123	383.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ,iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1632942_1	1380600.AUYN01000001_gene2373	0.0	1115.0	COG0308@1|root,COG0308@2|Bacteria,4NEJR@976|Bacteroidetes,1HYMW@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1632942_2	1380600.AUYN01000001_gene2374	1.23e-82	265.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_168198_1	317025.Tcr_0860	5.32e-69	222.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,460MD@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_563133_1	1123253.AUBD01000008_gene479	6.41e-14	68.6	2E3VP@1|root,32YSV@2|Bacteria,1NIQ8@1224|Proteobacteria,1T101@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_563133_2	1336803.PHEL49_1220	1.6e-48	165.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia,3VVY2@52959|Polaribacter	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1467224_1	398720.MED217_17040	1.57e-189	535.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia,2XIV3@283735|Leeuwenhoekiella	976|Bacteroidetes	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_1467224_2	1121931.AUHG01000010_gene110	8.87e-63	194.0	2E54M@1|root,32ZXJ@2|Bacteria,4NUYK@976|Bacteroidetes,1I501@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_451579_1	1123518.ARWI01000001_gene2355	5.18e-21	86.7	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,460WW@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_451579_2	90814.KL370891_gene1367	2.34e-61	199.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales	72273|Thiotrichales	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_845562_1	1121931.AUHG01000016_gene1048	9.38e-63	199.0	COG1633@1|root,COG1633@2|Bacteria,4NHJB@976|Bacteroidetes,1HXQJ@117743|Flavobacteriia	976|Bacteroidetes	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
k59_845562_2	1121931.AUHG01000016_gene1047	3.91e-31	115.0	COG1633@1|root,COG1633@2|Bacteria,4NIDS@976|Bacteroidetes,1HZ8G@117743|Flavobacteriia	976|Bacteroidetes	S	Tat (Twin-arginine translocation) pathway signal sequence containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
k59_903104_1	1380600.AUYN01000009_gene1911	7.89e-109	348.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_395012_1	929558.SMGD1_1283	3.8e-106	313.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2YTBB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Arginosuccinate synthase	-	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	Arginosuc_synth,ThiI,tRNA_Me_trans
k59_395012_2	563040.Saut_0036	2.81e-28	113.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1467313_1	563040.Saut_1699	2.57e-91	278.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2YMDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1467313_2	326298.Suden_0503	1.43e-16	79.7	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_1527003_1	326298.Suden_0536	1.32e-94	303.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_679896_1	929558.SMGD1_2858	1.87e-63	205.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_679896_2	326298.Suden_0992	3.47e-23	95.5	2A4DJ@1|root,30SZD@2|Bacteria,1PCJ7@1224|Proteobacteria,430CF@68525|delta/epsilon subdivisions,2YRYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2144_1	1565129.JSFF01000022_gene1417	2.99e-127	370.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,2Q97K@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518	Chorismate_synt
k59_397429_1	1250005.PHEL85_1102	0.0	923.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia,3VX58@52959|Polaribacter	976|Bacteroidetes	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1470137_1	1380600.AUYN01000009_gene1930	3.06e-160	479.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
k59_1301317_1	1392490.JHZX01000001_gene1308	3.91e-115	343.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1HWNF@117743|Flavobacteriia	976|Bacteroidetes	E	NADPH-dependent glutamate synthase beta chain and related	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1301317_2	1353276.JADR01000011_gene1530	2.92e-22	89.7	2E3J5@1|root,32YHJ@2|Bacteria,4NWA9@976|Bacteroidetes,1I53E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1301317_3	1004149.AFOE01000049_gene1960	2.97e-09	56.6	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia	976|Bacteroidetes	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
k59_679915_1	572480.Arnit_1984	1.8e-07	48.9	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2YQAF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RNA-binding protein	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_1244177_1	1168067.JAGP01000001_gene1116	1.17e-59	191.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,4622B@72273|Thiotrichales	72273|Thiotrichales	E	Tetrahydrodipicolinate N-succinyltransferase middle	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep_2,THDPS_M
k59_1131803_1	2423.NA23_0208290	3.41e-08	60.5	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2GC4I@200918|Thermotogae	200918|Thermotogae	J	PFAM CBS domain containing protein	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_1131803_2	1123514.KB905899_gene1349	4.38e-06	46.6	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria,462GA@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1357314_1	76114.ebA2758	0.000818	40.4	294JI@1|root,2ZRZ3@2|Bacteria,1REGD@1224|Proteobacteria,2VRDG@28216|Betaproteobacteria,2KYGP@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4863
k59_1357314_2	62928.azo3052	1.7e-83	261.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,2KY7V@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_1244182_1	1380600.AUYN01000009_gene2018	1.42e-193	542.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_1650744_1	983544.Lacal_0505	4.33e-296	810.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,1HWV9@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_1650744_2	1121912.AUHD01000001_gene2325	3.3e-79	238.0	29HVQ@1|root,304SU@2|Bacteria,4NP95@976|Bacteroidetes,1I26N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1536857_1	1168067.JAGP01000001_gene2116	2.53e-17	79.3	COG1116@1|root,COG1116@2|Bacteria,1R8N0@1224|Proteobacteria,1RYBX@1236|Gammaproteobacteria,46252@72273|Thiotrichales	72273|Thiotrichales	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_1536857_2	1123518.ARWI01000001_gene1244	7.04e-104	310.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RYYZ@1236|Gammaproteobacteria,461TG@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
k59_1254587_1	1192034.CAP_3681	5.5e-12	75.1	COG1357@1|root,COG5351@1|root,COG1357@2|Bacteria,COG5351@2|Bacteria,1N7U9@1224|Proteobacteria	1224|Proteobacteria	T	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169,Pentapeptide,Pentapeptide_4
k59_1594667_1	1172190.M947_10820	1.2e-120	351.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_520510_1	945713.IALB_2140	2e-95	288.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	metC	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
k59_803597_1	1122225.AULQ01000007_gene2289	1.78e-118	345.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69284_1	391603.FBALC1_07768	1.31e-281	778.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1536884_2	1121931.AUHG01000010_gene147	3.15e-80	246.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1HXAJ@117743|Flavobacteriia	976|Bacteroidetes	S	succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1481150_1	411154.GFO_1624	5.89e-105	323.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1HX0J@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_746486_2	90814.KL370891_gene1422	2.89e-06	50.1	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,45ZUD@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the folylpolyglutamate synthase family	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_125117_1	397290.C810_01730	1.68e-15	79.3	28MFC@1|root,2ZASU@2|Bacteria,1TSRB@1239|Firmicutes,24DBW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_691121_1	945713.IALB_0782	1.63e-118	348.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95,1.17.1.9	ko:K00058,ko:K00122	ko00260,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00519,R01513	RC00031,RC02796	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1707245_1	1380600.AUYN01000006_gene314	8.27e-111	330.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_182503_1	1178825.ALIH01000001_gene2355	2e-48	164.0	COG0810@1|root,COG0810@2|Bacteria,4NN8A@976|Bacteroidetes,1I18J@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1029313_1	929558.SMGD1_1729	4.82e-171	500.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1141480_1	1347342.BN863_14780	1.01e-105	315.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1HYNA@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_803638_1	1137281.D778_01916	6.43e-129	388.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_69337_1	448385.sce8106	2.52e-66	225.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
k59_1084781_1	411476.BACOVA_02491	4.53e-78	254.0	COG0547@1|root,COG0547@2|Bacteria,4P1C6@976|Bacteroidetes,2FMAD@200643|Bacteroidia,4AMQI@815|Bacteroidaceae	976|Bacteroidetes	E	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_350757_1	536232.CLM_1993	3.24e-22	100.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,36EAU@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_746546_1	411154.GFO_0114	6.24e-53	174.0	COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia	976|Bacteroidetes	H	PFAM Acyl-protein synthetase, LuxE	luxE	-	-	-	-	-	-	-	-	-	-	-	LuxE
k59_746546_2	1121931.AUHG01000010_gene769	3.03e-99	300.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_915989_2	1123228.AUIH01000027_gene3445	1.59e-10	60.8	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XJ03@135619|Oceanospirillales	135619|Oceanospirillales	P	Trk system potassium uptake protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_691166_1	1380600.AUYN01000010_gene842	9.21e-120	383.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1084808_1	1484460.JSWG01000006_gene2924	9.68e-100	294.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1HX2T@117743|Flavobacteriia	976|Bacteroidetes	S	TIGR02453 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_1084808_2	1046627.BZARG_157	4.73e-137	393.0	COG0101@1|root,COG0101@2|Bacteria,4NG3N@976|Bacteroidetes,1HX0T@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_1650869_1	1121931.AUHG01000010_gene710	3.23e-83	254.0	COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,1I5ZB@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1312457_2	113395.AXAI01000015_gene486	1.37e-44	153.0	COG0411@1|root,COG0411@2|Bacteria,1R3YN@1224|Proteobacteria,2U2IG@28211|Alphaproteobacteria,3JXXI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
k59_239058_1	1121931.AUHG01000012_gene2667	1.22e-40	143.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_239058_2	1121931.AUHG01000012_gene2668	4.06e-112	327.0	COG1091@1|root,COG1091@2|Bacteria,4NF71@976|Bacteroidetes,1HZ17@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1650888_1	400682.PAC_15705453	1.88e-53	169.0	COG2154@1|root,KOG4073@2759|Eukaryota	2759|Eukaryota	H	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008124,GO:0016829,GO:0016835,GO:0016836,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
k59_1650888_2	290397.Adeh_2654	9.16e-09	57.8	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1650892_1	929558.SMGD1_2071	3.99e-150	441.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_8,dCache_3
k59_408021_1	1046627.BZARG_2539	1.19e-08	53.9	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1HX4U@117743|Flavobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_408021_2	385682.AFSL01000088_gene861	2.38e-58	183.0	COG5646@1|root,COG5646@2|Bacteria,4P9D6@976|Bacteroidetes,2G1H9@200643|Bacteroidia,3XKZW@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_408021_3	1341181.FLJC2902T_20740	1.01e-86	258.0	COG1670@1|root,COG1670@2|Bacteria,4NNZ3@976|Bacteroidetes,1I2GE@117743|Flavobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_408021_4	886377.Murru_1142	2.02e-101	296.0	COG0262@1|root,COG0262@2|Bacteria,4NMP3@976|Bacteroidetes	976|Bacteroidetes	H	Pfam RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
k59_1594789_2	768670.Calni_0184	4.62e-23	102.0	COG3434@1|root,COG3434@2|Bacteria,2GEU7@200930|Deferribacteres	200930|Deferribacteres	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1650899_1	1178825.ALIH01000002_gene883	5.16e-115	365.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_295053_1	504487.JCM19302_505	1.76e-123	362.0	COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,1HX2Y@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1084845_1	641526.ADIWIN_3257	2.64e-99	307.0	COG5492@1|root,COG5492@2|Bacteria,4PM9P@976|Bacteroidetes,1I0RN@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
k59_1084845_2	1469557.JSWF01000017_gene2279	1.2e-91	276.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_916041_1	1380600.AUYN01000012_gene2955	1.53e-126	368.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1HXBD@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_464971_1	1469557.JSWF01000014_gene2701	1.13e-37	141.0	COG0545@1|root,COG0545@2|Bacteria,4NJPK@976|Bacteroidetes,1HY2J@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_464971_2	1317122.ATO12_19810	1.83e-16	76.6	COG3637@1|root,COG3637@2|Bacteria,4NM4E@976|Bacteroidetes,1I1FR@117743|Flavobacteriia,2YH3P@290174|Aquimarina	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
k59_182608_1	929558.SMGD1_1763	1.6e-65	213.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1141580_1	572480.Arnit_2826	7.97e-60	196.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1141580_2	572480.Arnit_2825	8.5e-41	139.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_1367264_1	1380600.AUYN01000009_gene1467	2.67e-102	304.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1HXXI@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1367264_2	983544.Lacal_1714	3.42e-43	144.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1I1BI@117743|Flavobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_916045_1	555793.WSK_2080	7.34e-27	115.0	COG5281@1|root,COG5412@1|root,COG5281@2|Bacteria,COG5412@2|Bacteria,1Q6YW@1224|Proteobacteria,2VD2S@28211|Alphaproteobacteria,2K6DJ@204457|Sphingomonadales	204457|Sphingomonadales	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1084854_1	1121931.AUHG01000017_gene1535	3.03e-116	338.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1HXP9@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_971170_1	563040.Saut_1649	1.85e-129	376.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1368822_2	1280953.HOC_00570	4.29e-39	150.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,43X80@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_13503_1	5786.XP_003294148.1	1.87e-15	80.9	COG0642@1|root,KOG0519@2759|Eukaryota,3XEXA@554915|Amoebozoa	554915|Amoebozoa	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_409718_1	391603.FBALC1_00410	5.79e-53	179.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_579336_1	1458357.BG58_38895	3.54e-24	106.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,1K2P0@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1425986_1	63737.Npun_F5467	2.11e-51	185.0	COG2202@1|root,COG3852@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1HTQ5@1161|Nostocales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1765798_1	929558.SMGD1_0956	3.79e-59	193.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YNAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_240700_1	1140.Synpcc7942_2390	1.58e-19	88.6	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1G02W@1117|Cyanobacteria,1GZHA@1129|Synechococcus	1117|Cyanobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_240700_2	1123514.KB905901_gene74	6.99e-123	362.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,460XA@72273|Thiotrichales	72273|Thiotrichales	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_1538573_1	411154.GFO_3078	7.58e-43	155.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1652638_1	1406840.Q763_16115	3.19e-45	158.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HYHY@117743|Flavobacteriia,2NU1A@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1652638_5	338966.Ppro_0548	8.56e-26	104.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,43W11@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k59_352461_1	1347342.BN863_7420	1.41e-47	155.0	COG4807@1|root,COG4807@2|Bacteria,4NSYM@976|Bacteroidetes,1I3ZP@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
k59_352461_2	867900.Celly_0104	2.16e-78	243.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1HYKT@117743|Flavobacteriia,1F84B@104264|Cellulophaga	976|Bacteroidetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_1368861_1	1379281.AVAG01000029_gene11	3.17e-11	63.9	COG3168@1|root,COG3168@2|Bacteria,1N39F@1224|Proteobacteria,42U30@68525|delta/epsilon subdivisions,2WRT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_1368861_2	1232410.KI421416_gene2558	2.91e-30	122.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43S8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1426012_1	1121931.AUHG01000011_gene1943	2.29e-82	246.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8R@976|Bacteroidetes,1I3CY@117743|Flavobacteriia	976|Bacteroidetes	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
k59_522415_1	595460.RRSWK_07082	8.33e-62	210.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_522415_2	1250005.PHEL85_2086	7.36e-19	88.2	COG0265@1|root,COG0657@1|root,COG0265@2|Bacteria,COG0657@2|Bacteria,4PKDQ@976|Bacteroidetes,1HXR3@117743|Flavobacteriia	976|Bacteroidetes	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_409779_1	1380600.AUYN01000006_gene335	9.81e-115	357.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1709167_1	1270193.JARP01000002_gene1036	7.35e-252	725.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia,2P016@237|Flavobacterium	976|Bacteroidetes	KT	Regulator	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_368972_1	326298.Suden_1822	3.58e-181	527.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_1385324_1	1250232.JQNJ01000001_gene2792	7.14e-15	69.7	2DM4Z@1|root,31R64@2|Bacteria,4NRZQ@976|Bacteroidetes,1I3K5@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
k59_1783103_1	944547.ABLL_1796	5.15e-27	107.0	COG1672@1|root,COG1672@2|Bacteria,1PZGT@1224|Proteobacteria,42QN9@68525|delta/epsilon subdivisions,2YNKC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_1783103_2	387093.SUN_1096	6.1e-28	105.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2YP7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_595260_1	1565129.JSFF01000001_gene1095	2.84e-135	395.0	COG1396@1|root,COG1396@2|Bacteria,1R3Z8@1224|Proteobacteria,1RRMV@1236|Gammaproteobacteria,2QAI5@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3612,HTH_19,HTH_3,Peptidase_M78
k59_711324_1	1123518.ARWI01000001_gene326	7.42e-116	340.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,4621W@72273|Thiotrichales	72273|Thiotrichales	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_711324_2	1123518.ARWI01000001_gene325	2.8e-71	224.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,1RPFP@1236|Gammaproteobacteria,461QY@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
k59_1725744_1	1380600.AUYN01000010_gene842	6.92e-96	311.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1725744_2	1392490.JHZX01000001_gene2723	5.4e-10	59.3	COG3064@1|root,COG3064@2|Bacteria,4NESI@976|Bacteroidetes,1HXS4@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_933531_1	1565129.JSFF01000030_gene2837	2.2e-120	355.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,2Q93J@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2
k59_87891_1	1492737.FEM08_02470	5.67e-145	422.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia,2NSA5@237|Flavobacterium	976|Bacteroidetes	G	transporter	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
k59_1331702_1	1380600.AUYN01000007_gene3109	9.74e-251	695.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IJAQ@117743|Flavobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_539272_1	1172190.M947_06455	2.08e-23	97.4	COG0467@1|root,COG0467@2|Bacteria,1QV0R@1224|Proteobacteria,42QV0@68525|delta/epsilon subdivisions,2YNWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Zonular occludens toxin (Zot)	-	-	-	ko:K10954	ko05110,map05110	-	-	-	ko00000,ko00001,ko02042	-	-	-	Zot
k59_1442145_2	1449069.JMLO01000001_gene2011	1.43e-14	74.7	COG0583@1|root,COG0583@2|Bacteria,2H6E4@201174|Actinobacteria,4FWXR@85025|Nocardiaceae	201174|Actinobacteria	K	LysR substrate binding domain	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_986176_1	1123518.ARWI01000001_gene2428	4.58e-104	309.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,45ZQT@72273|Thiotrichales	72273|Thiotrichales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_986187_1	1122225.AULQ01000009_gene364	3.87e-11	60.5	COG0662@1|root,COG0662@2|Bacteria,4NQ4K@976|Bacteroidetes,1I2VJ@117743|Flavobacteriia	976|Bacteroidetes	G	domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
k59_986187_2	1469557.JSWF01000027_gene1905	8.47e-35	129.0	COG1216@1|root,COG1216@2|Bacteria,4NNFE@976|Bacteroidetes,1I2BX@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_986188_2	317025.Tcr_0613	1.14e-34	123.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,460X5@72273|Thiotrichales	72273|Thiotrichales	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_29548_1	411154.GFO_3446	5.25e-16	76.6	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1HWWX@117743|Flavobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
k59_29548_2	688270.Celal_1861	1.18e-11	65.1	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HYK4@117743|Flavobacteriia,1FAB7@104264|Cellulophaga	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_483547_1	313603.FB2170_14593	5.79e-183	527.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1IJ95@117743|Flavobacteriia,2PH3B@252356|Maribacter	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1442165_1	1380600.AUYN01000001_gene2463	2.36e-81	244.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HX6R@117743|Flavobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1442165_2	880071.Fleli_0751	1.62e-76	236.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_1442165_3	1380600.AUYN01000001_gene2464	1.61e-85	276.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_1273235_1	929558.SMGD1_2266	1.38e-103	306.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_1273235_2	563040.Saut_0769	8.62e-62	196.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2YMZQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_986201_1	411154.GFO_2724	7.89e-91	286.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_426509_1	945713.IALB_0706	6.97e-43	158.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	-
k59_29557_1	1123514.KB905899_gene977	8.46e-74	231.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,1RPRZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_823148_1	1121931.AUHG01000011_gene1716	2.17e-99	302.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1HZ60@117743|Flavobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_1554897_1	521719.ATXQ01000002_gene2380	5.15e-21	94.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YER0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1273252_2	754436.JCM19237_5490	1.73e-19	89.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUBG@135623|Vibrionales	135623|Vibrionales	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K20919	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_1500365_1	1380600.AUYN01000009_gene1794	1.09e-134	384.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
k59_823151_1	1353528.DT23_15715	7.02e-79	246.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2TUNR@28211|Alphaproteobacteria,2XKQ3@285107|Thioclava	28211|Alphaproteobacteria	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1047398_1	1123514.KB905900_gene2063	3.74e-216	641.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_764627_1	504487.JCM19302_3151	6.32e-85	254.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1HXDV@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_764627_2	504487.JCM19302_3150	7.44e-12	60.5	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1I45R@117743|Flavobacteriia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_313761_1	1347342.BN863_14160	6.84e-100	310.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_313761_2	391603.FBALC1_07343	2.73e-51	164.0	COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,1I310@117743|Flavobacteriia	976|Bacteroidetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_313761_3	1380600.AUYN01000012_gene2955	7.65e-15	73.6	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1HXBD@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_933626_1	945713.IALB_0835	2.79e-66	220.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_369117_1	411154.GFO_2176	4.15e-37	136.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,1HWVE@117743|Flavobacteriia	976|Bacteroidetes	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_1725863_1	1121931.AUHG01000012_gene2519	2.25e-78	245.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1HY14@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1048972_2	1484460.JSWG01000009_gene271	1.25e-86	255.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
k59_1048972_3	1178825.ALIH01000013_gene510	4.99e-50	162.0	2E858@1|root,332IT@2|Bacteria,4NVGV@976|Bacteroidetes,1I56Y@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1048972_4	1178825.ALIH01000013_gene509	1.32e-59	190.0	COG0204@1|root,COG0204@2|Bacteria,4NHC8@976|Bacteroidetes,1HY24@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1784953_1	317025.Tcr_1150	5.94e-137	429.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_1333790_1	1380600.AUYN01000010_gene862	1.28e-57	192.0	COG1225@1|root,COG1225@2|Bacteria,4NH32@976|Bacteroidetes,1HWQJ@117743|Flavobacteriia	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
k59_31196_1	596151.DesfrDRAFT_2297	3.63e-15	84.3	COG4974@1|root,COG4974@2|Bacteria,1RBMG@1224|Proteobacteria,42R21@68525|delta/epsilon subdivisions,2WN4K@28221|Deltaproteobacteria,2M90A@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
k59_370925_1	1565129.JSFF01000027_gene3330	3.49e-69	224.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,2Q93G@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	Z012_02960	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_880012_1	1537915.JU57_01670	5.81e-47	154.0	COG3658@1|root,COG3658@2|Bacteria,1Q5XQ@1224|Proteobacteria,43216@68525|delta/epsilon subdivisions,2YSF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_1161895_1	572480.Arnit_2382	1.42e-151	429.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2YMZH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_654680_1	504487.JCM19302_563	1.23e-25	102.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
k59_654680_2	1341155.FSS13T_08810	2.15e-65	202.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,2NW14@237|Flavobacterium	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k59_1275178_1	1380600.AUYN01000009_gene2167	1.49e-171	481.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,1HYJ6@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_1275178_2	641526.ADIWIN_3366	3e-14	67.4	2ADBR@1|root,31316@2|Bacteria,4NQ7M@976|Bacteroidetes,1I2VQ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2853
k59_766466_1	768671.ThimaDRAFT_4882	4.78e-90	273.0	COG3385@1|root,COG3385@2|Bacteria,1N963@1224|Proteobacteria,1SE1N@1236|Gammaproteobacteria,1WZEW@135613|Chromatiales	135613|Chromatiales	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_1049003_1	1123518.ARWI01000001_gene2424	7.74e-178	502.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,45ZV7@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_1049003_2	1123518.ARWI01000001_gene2423	4.57e-47	156.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1444060_1	1121931.AUHG01000010_gene744	4.85e-38	136.0	COG0204@1|root,COG0204@2|Bacteria,4NGR9@976|Bacteroidetes,1HZE7@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_1444060_2	411154.GFO_0086	8.22e-73	227.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_145211_1	929558.SMGD1_1598	2.72e-102	308.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2YTJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_825266_1	1380600.AUYN01000001_gene2455	1.72e-143	412.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_202974_2	317025.Tcr_1767	3.28e-80	258.0	COG3173@1|root,COG3173@2|Bacteria,1Q5UX@1224|Proteobacteria,1RS6I@1236|Gammaproteobacteria,462D2@72273|Thiotrichales	72273|Thiotrichales	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_880080_1	1237149.C900_02258	3.81e-05	45.1	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,47RS3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_880080_2	643867.Ftrac_1556	1.17e-25	100.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,47K5Q@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_1161951_1	1280001.BAOA01000115_gene100	4.36e-35	131.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RPR0@1236|Gammaproteobacteria,1XUU1@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	VP1483	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS
k59_825285_1	323850.Shew_2438	1.51e-76	234.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,2Q9QB@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
k59_654752_1	1380600.AUYN01000001_gene2435	3.38e-70	216.0	2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1I25Z@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1049072_1	326298.Suden_1642	1.25e-12	68.9	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1049072_2	929558.SMGD1_0708	2.66e-92	274.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2YPMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_1049072_3	1249480.B649_01735	9.38e-09	55.1	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_428558_1	598659.NAMH_0214	5.46e-57	189.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42QPW@68525|delta/epsilon subdivisions,2YP0Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1275273_1	572480.Arnit_0064	6.66e-23	96.3	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_1502496_1	563040.Saut_1253	6.47e-107	317.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_1275282_1	1353276.JADR01000008_gene887	9.31e-68	215.0	COG0845@1|root,COG0845@2|Bacteria,4NMQS@976|Bacteroidetes,1I1M7@117743|Flavobacteriia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_1162013_1	1392490.JHZX01000001_gene2108	6.4e-97	313.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_1105121_1	459349.CLOAM0486	1.12e-66	227.0	COG0210@1|root,COG0210@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1105121_2	1340434.AXVA01000027_gene1060	1.52e-100	318.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1V7Y2@1239|Firmicutes,4HBTD@91061|Bacilli,1ZBND@1386|Bacillus	91061|Bacilli	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k59_145284_1	1123518.ARWI01000001_gene70	4.58e-71	218.0	COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,1S8FV@1236|Gammaproteobacteria,462NR@72273|Thiotrichales	72273|Thiotrichales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_145284_2	1123518.ARWI01000001_gene67	7.89e-72	225.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,460B3@72273|Thiotrichales	72273|Thiotrichales	C	PFAM NADH flavin oxidoreductase NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
k59_1444138_1	94122.Shewana3_2831	1.06e-13	67.4	COG2913@1|root,COG2913@2|Bacteria,1NAIV@1224|Proteobacteria,1SD2R@1236|Gammaproteobacteria,2QC92@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Protein of unknown function (DUF3192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3192
k59_106859_1	1121931.AUHG01000017_gene1500	1.28e-143	429.0	COG4399@1|root,COG4399@2|Bacteria,4PM7W@976|Bacteroidetes,1HX9F@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_219563_1	572480.Arnit_0435	3.05e-67	217.0	28JFR@1|root,2Z99N@2|Bacteria,1R7C5@1224|Proteobacteria,42T6I@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1801762_1	118005.AWNK01000003_gene2450	4.27e-114	356.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,PHP,PHP_C
k59_1459678_1	1237149.C900_03125	1.7e-38	144.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
k59_219585_1	572480.Arnit_2270	7.17e-96	299.0	COG4206@1|root,COG4206@2|Bacteria,1R0RR@1224|Proteobacteria,42TBR@68525|delta/epsilon subdivisions,2YPNP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_783607_1	1137281.D778_00430	1.02e-53	173.0	COG4659@1|root,COG4659@2|Bacteria,4NPUB@976|Bacteroidetes,1I2MB@117743|Flavobacteriia	976|Bacteroidetes	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k59_730323_1	1380600.AUYN01000001_gene2798	4.4e-300	875.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_948995_1	425104.Ssed_0082	2.34e-53	170.0	COG1886@1|root,COG1886@2|Bacteria,1N815@1224|Proteobacteria,1SEUM@1236|Gammaproteobacteria,2QC9S@267890|Shewanellaceae	1236|Gammaproteobacteria	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_948995_2	318161.Sden_3662	5.49e-15	73.6	COG1868@1|root,COG1868@2|Bacteria,1NKVA@1224|Proteobacteria,1SITX@1236|Gammaproteobacteria,2Q9P2@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	-	-	-	-	-	-	-	-	-	FliMN_C
k59_730334_1	1123518.ARWI01000001_gene783	6.51e-210	604.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,45ZRC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1064373_1	411154.GFO_3146	9.22e-174	489.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia	976|Bacteroidetes	O	molecular chaperone	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_1064373_2	1121931.AUHG01000010_gene121	1.18e-16	75.1	COG2318@1|root,COG2318@2|Bacteria,4NUH8@976|Bacteroidetes,1I4KA@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
k59_838717_1	323850.Shew_0429	4.28e-82	248.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,2Q8VA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k59_949034_1	1380600.AUYN01000012_gene2973	5.34e-27	103.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_1459741_1	1172190.M947_03485	8.28e-180	508.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1459741_2	563040.Saut_1701	2.01e-34	122.0	2BM55@1|root,32FNN@2|Bacteria,1Q0P6@1224|Proteobacteria,42SB7@68525|delta/epsilon subdivisions,2YPGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA replication regulator	hobA	-	-	-	-	-	-	-	-	-	-	-	HobA
k59_1064397_1	709032.Sulku_1757	4.14e-107	338.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_1064397_2	563040.Saut_1382	1.01e-66	206.0	2AIVI@1|root,30TB8@2|Bacteria,1PD2X@1224|Proteobacteria,42TB3@68525|delta/epsilon subdivisions,2YPG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_332545_1	1172190.M947_06735	2.41e-91	268.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2YNWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_332545_2	563040.Saut_1766	5.22e-22	94.7	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_387516_1	929558.SMGD1_2350	1.94e-105	319.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_106974_1	1121896.JMLU01000004_gene2607	1.82e-65	213.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia,2NUHC@237|Flavobacterium	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_221806_2	929558.SMGD1_2870	5.14e-23	97.1	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions,2YMUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
k59_163453_1	1115512.EH105704_19_00250	5.01e-08	54.3	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,3XP8H@561|Escherichia	1236|Gammaproteobacteria	L	Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process	nudF	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_3126	NUDIX
k59_163453_2	1415778.JQMM01000001_gene752	8.19e-61	192.0	COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1SA3I@1236|Gammaproteobacteria,1JBXJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1249)	-	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
k59_1294293_1	563040.Saut_1458	1.4e-89	270.0	2CJ90@1|root,33RG4@2|Bacteria,1Q090@1224|Proteobacteria,42RSY@68525|delta/epsilon subdivisions,2YP4W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
k59_1007218_1	367737.Abu_1752	2.46e-66	209.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,42QZI@68525|delta/epsilon subdivisions,2YPPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
k59_674197_1	1232410.KI421418_gene2283	5.36e-122	356.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,43TZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_504119_1	1443665.JACA01000003_gene914	3.41e-89	279.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia,2YI30@290174|Aquimarina	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_558419_1	1121912.AUHD01000002_gene3279	7.4e-32	114.0	COG3577@1|root,COG3577@2|Bacteria,4NNI0@976|Bacteroidetes,1I1Z6@117743|Flavobacteriia	976|Bacteroidetes	S	protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
k59_558419_2	886377.Murru_1804	2.97e-37	132.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia	976|Bacteroidetes	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_614148_2	626418.bglu_1g20680	8.15e-07	50.4	2C2XM@1|root,2ZKBG@2|Bacteria,1P9D3@1224|Proteobacteria,2W6BU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1294309_1	1246459.KB898374_gene3957	7.9e-08	55.1	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,2U0MU@28211|Alphaproteobacteria,4B8R7@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
k59_1294309_2	90814.KL370891_gene1464	6.01e-57	180.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,460TM@72273|Thiotrichales	72273|Thiotrichales	K	PFAM MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_1294309_3	1123518.ARWI01000001_gene2191	1.29e-56	176.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,460XH@72273|Thiotrichales	72273|Thiotrichales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1294309_4	1123514.KB905899_gene596	5.06e-231	659.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,45ZNZ@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_898033_1	1121931.AUHG01000011_gene2189	2.06e-102	306.0	COG3182@1|root,COG3182@2|Bacteria,4NEXX@976|Bacteroidetes,1HYWR@117743|Flavobacteriia	976|Bacteroidetes	S	PepSY-associated TM helix	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
k59_898033_2	1121931.AUHG01000011_gene2188	3.99e-32	123.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1353256_1	504487.JCM19302_3241	1.6e-43	149.0	COG0622@1|root,COG0622@2|Bacteria,4NGFH@976|Bacteroidetes,1HYAG@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_1353256_2	1137281.D778_02814	5.21e-62	191.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1I32H@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
k59_951098_1	1492737.FEM08_17290	2.74e-170	485.0	COG3387@1|root,COG3387@2|Bacteria,4NGFS@976|Bacteroidetes,1I0H9@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_36
k59_951098_2	700598.Niako_0535	7.8e-82	265.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQU8@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_335107_1	1121931.AUHG01000012_gene2524	6.44e-164	466.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
k59_1353279_1	85643.Tmz1t_0598	9.84e-43	153.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,2KUCA@206389|Rhodocyclales	206389|Rhodocyclales	EGP	drug resistance transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_1747564_1	1537917.JU82_03445	1.76e-27	102.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_1747564_2	525898.Sdel_2271	1.65e-36	126.0	28QM5@1|root,3192M@2|Bacteria,1Q1JK@1224|Proteobacteria,42TV6@68525|delta/epsilon subdivisions,2YPT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1574904_2	537972.ABQU01000028_gene507	7.16e-64	203.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2YNZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_1294347_1	323850.Shew_1221	2.06e-30	116.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,2Q8YR@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_1294347_2	323850.Shew_1220	7.1e-51	177.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,2QA08@267890|Shewanellaceae	1236|Gammaproteobacteria	CI	PFAM biotin lipoyl attachment domain-containing protein	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_674255_1	1249480.B649_10330	5.8e-20	85.1	COG2165@1|root,COG2165@2|Bacteria,1QUIP@1224|Proteobacteria,42VHZ@68525|delta/epsilon subdivisions,2YQA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_1630117_2	1348657.M622_00300	4.72e-33	119.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,2WGPE@28216|Betaproteobacteria,2KXA4@206389|Rhodocyclales	206389|Rhodocyclales	G	Cupin domain	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
k59_504175_1	411154.GFO_2713	9.58e-45	145.0	2CA8N@1|root,32YKH@2|Bacteria,4NX90@976|Bacteroidetes,1I4C1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_504175_2	411154.GFO_2714	5.19e-35	124.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1HZGZ@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_898078_1	411154.GFO_3320	3.4e-133	393.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_1462236_1	317025.Tcr_2184	6.79e-103	322.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,4600B@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_1462236_2	1123514.KB905900_gene2226	1.29e-73	229.0	COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,460DE@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1294363_1	1178825.ALIH01000001_gene2536	1.08e-86	271.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_1294363_2	983548.Krodi_0581	2.01e-29	115.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia,37DYR@326319|Dokdonia	976|Bacteroidetes	M	Mur ligase family, glutamate ligase domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_786234_1	1123234.AUKI01000011_gene1219	4.34e-36	133.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_446838_1	572480.Arnit_2596	1e-106	315.0	COG5239@1|root,COG5239@2|Bacteria,1QZF3@1224|Proteobacteria,42XN9@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos
k59_49220_1	411154.GFO_0748	4.51e-58	186.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1I48G@117743|Flavobacteriia	976|Bacteroidetes	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
k59_49220_2	746697.Aeqsu_2026	1.98e-17	79.3	COG1878@1|root,COG1878@2|Bacteria,4NFYB@976|Bacteroidetes,1IIVK@117743|Flavobacteriia	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_1574955_1	1123518.ARWI01000001_gene726	3.07e-76	237.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,461JD@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1226926_1	1197477.IA57_00105	1.22e-106	314.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1HZ8D@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_1007345_1	944547.ABLL_2373	7.02e-35	126.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2YMKE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar biosynthetic protein fliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_1574963_1	323850.Shew_2544	4.25e-64	212.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,2Q949@267890|Shewanellaceae	1236|Gammaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1226932_1	1237149.C900_03678	2.22e-85	262.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,47JHT@768503|Cytophagia	976|Bacteroidetes	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1353353_1	90814.KL370891_gene1921	6.02e-74	232.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,460S1@72273|Thiotrichales	72273|Thiotrichales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_1353353_2	1123514.KB905900_gene2089	2.74e-65	214.0	COG0526@1|root,COG0526@2|Bacteria,1RCTX@1224|Proteobacteria,1S4XW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_1124547_1	1121931.AUHG01000011_gene2368	2.89e-102	318.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_674326_1	1434325.AZQN01000011_gene3787	3.67e-05	45.4	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,47P6X@768503|Cytophagia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_674326_2	465541.ATCJ01000005_gene6173	3.27e-11	61.6	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_1226939_1	326298.Suden_0328	1.2e-70	213.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2YPKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_1226939_2	563040.Saut_0292	4.61e-97	290.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2YM93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1690729_1	1191523.MROS_2577	2.11e-80	263.0	COG0308@1|root,COG0823@1|root,COG4775@1|root,COG0308@2|Bacteria,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,CarbopepD_reg_2,NAAA-beta,PD40,Peptidase_M1,Phospholip_B
k59_1007365_1	326298.Suden_1132	1.16e-78	251.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_1007365_2	1249480.B649_06400	3.07e-08	53.5	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2YMH3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_1066767_1	1172190.M947_11205	2.42e-152	438.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2YMNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_163608_1	573061.Clocel_3315	0.000803	50.1	COG2247@1|root,COG2374@1|root,COG5184@1|root,COG2247@2|Bacteria,COG2374@2|Bacteria,COG5184@2|Bacteria,1TS5I@1239|Firmicutes,24A8Z@186801|Clostridia,36KA8@31979|Clostridiaceae	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CHB_HEX_C_1,Cu_amine_oxidN1,RCC1,RCC1_2
k59_504264_1	745718.JADT01000019_gene1503	7.28e-47	169.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_674376_2	523791.Kkor_1051	7.21e-41	152.0	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XJ19@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3
k59_951214_1	1460635.JCM19038_3556	9.1e-06	51.6	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
k59_1522216_1	748247.AZKH_0318	2.33e-38	142.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,2KW83@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16
k59_1181314_1	411154.GFO_1449	1.56e-116	337.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1HX58@117743|Flavobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_514609_1	425104.Ssed_3705	0.000335	45.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QACE@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_1757973_1	323850.Shew_2188	1.69e-153	444.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,2Q8SR@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	rpfB	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_1418715_1	411154.GFO_1535	8.27e-39	140.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	res	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_232960_1	509635.N824_26250	1.98e-29	120.0	COG2244@1|root,COG2244@2|Bacteria,4NFKD@976|Bacteroidetes,1IR3Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k59_1588636_1	563040.Saut_1663	3.33e-123	357.0	2BUD7@1|root,32PP4@2|Bacteria,1Q4AN@1224|Proteobacteria,42YRC@68525|delta/epsilon subdivisions,2YR91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_684982_1	572480.Arnit_0054	1.62e-97	303.0	COG0840@1|root,COG2202@1|root,COG0840@2|Bacteria,COG2202@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	methyl-accepting chemotaxis protein	mcp64H-1	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k59_63328_1	1380600.AUYN01000001_gene2594	9.87e-84	254.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia	976|Bacteroidetes	EH	Aminotransferase class IV	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_403690_1	929558.SMGD1_0408	1.19e-54	191.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2YRCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_854881_1	1565129.JSFF01000004_gene3123	3.43e-68	216.0	28HJP@1|root,2Z7UT@2|Bacteria,1MWM4@1224|Proteobacteria,1RQNG@1236|Gammaproteobacteria,2QAXN@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2955)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2955,FUSC_2
k59_1476517_1	1178825.ALIH01000002_gene896	3.88e-122	364.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_1420144_1	411154.GFO_2998	3.08e-134	402.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_1702753_1	1347342.BN863_13880	1.59e-84	254.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1HWJY@117743|Flavobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_1702753_2	1392490.JHZX01000001_gene3378	2.39e-300	844.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_799232_2	1380384.JADN01000003_gene796	5.44e-235	647.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1HY0P@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_799232_3	143224.JQMD01000002_gene3280	1.86e-16	78.6	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
k59_64842_1	1123518.ARWI01000001_gene2162	9.86e-125	365.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1137406_1	1322246.BN4_12315	5.35e-11	68.6	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HTH_31,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_742228_1	1392490.JHZX01000001_gene348	1.27e-211	593.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
k59_742228_2	1392490.JHZX01000001_gene347	1.58e-180	518.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,1HYGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	DUF4980,Glyco_hydro_32C,Glyco_hydro_32N
k59_1759500_1	1122225.AULQ01000007_gene2365	2.79e-57	180.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1I1XW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_799256_1	323850.Shew_2693	2.18e-81	250.0	2C3X5@1|root,32RCX@2|Bacteria,1RKW4@1224|Proteobacteria,1S73W@1236|Gammaproteobacteria,2QC0X@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_629671_2	1415778.JQMM01000001_gene72	5.3e-47	163.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1J4KT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1476553_1	1121931.AUHG01000016_gene989	1.26e-24	100.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1476553_2	1121931.AUHG01000016_gene987	2.21e-61	192.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1192175_2	1168067.JAGP01000001_gene1757	2.49e-92	278.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,463P8@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator, LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1646497_1	1123518.ARWI01000001_gene1437	2.49e-19	81.3	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,1SCEN@1236|Gammaproteobacteria,461BY@72273|Thiotrichales	72273|Thiotrichales	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1646497_2	1123518.ARWI01000001_gene1438	3.4e-196	557.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_460427_1	153721.MYP_702	6.26e-14	80.1	COG2445@1|root,COG2445@2|Bacteria,4NU49@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1759510_1	906888.JCM19314_236	3.4e-32	112.0	2E5CT@1|root,3304V@2|Bacteria,4NUT8@976|Bacteroidetes,1I511@117743|Flavobacteriia,3HKRR@363408|Nonlabens	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1759510_2	1122225.AULQ01000004_gene2182	4.23e-99	306.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k59_178067_1	1121931.AUHG01000010_gene835	1.98e-179	554.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_120994_1	563040.Saut_1184	1.16e-87	270.0	COG3174@1|root,COG3174@2|Bacteria,1RA19@1224|Proteobacteria,42PB8@68525|delta/epsilon subdivisions,2YNQN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010
k59_1307931_1	983545.Glaag_1762	1.5e-95	299.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,465QV@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980	ABC_membrane,ABC_tran
k59_1307931_2	1123518.ARWI01000001_gene2004	6.9e-181	509.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,460MK@72273|Thiotrichales	72273|Thiotrichales	M	Lipid A biosynthesis	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_290660_1	1178825.ALIH01000003_gene2001	9.03e-121	375.0	COG0697@1|root,COG0697@2|Bacteria,4PKRH@976|Bacteroidetes,1HX4A@117743|Flavobacteriia	976|Bacteroidetes	EG	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_967976_1	572480.Arnit_0712	5.42e-129	385.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,42P6Y@68525|delta/epsilon subdivisions,2YMZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_1759554_1	1380600.AUYN01000009_gene1571	3.32e-58	192.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
k59_1759554_2	641526.ADIWIN_2979	8.13e-24	100.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_742286_1	504487.JCM19302_385	3.22e-61	201.0	COG5000@1|root,COG5000@2|Bacteria,4PKJN@976|Bacteroidetes,1IJB1@117743|Flavobacteriia	976|Bacteroidetes	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1420237_2	1121931.AUHG01000011_gene2144	1.38e-56	196.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1080663_2	326298.Suden_0739	2.5e-77	233.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_1363023_1	317025.Tcr_1141	1.23e-63	206.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	H( )-stimulated, divalent metal cation uptake system	mntH	GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1902600	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iSF_1195.SF2457	Nramp
k59_1363023_2	1123518.ARWI01000001_gene281	1.72e-100	304.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,46066@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_178119_1	1305737.JAFX01000001_gene2308	7.73e-186	534.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
k59_178119_2	1121898.Q766_08840	2.84e-34	119.0	2E6UP@1|root,331EC@2|Bacteria,4NUYV@976|Bacteroidetes,1I59A@117743|Flavobacteriia,2NX3Q@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_178119_3	1380600.AUYN01000001_gene2710	2.58e-280	786.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
k59_629750_1	572480.Arnit_2700	1.43e-74	229.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2YNRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	UPF0056 inner membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_629750_2	572480.Arnit_0821	3.56e-11	61.2	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2YN0R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_346615_1	1197477.IA57_12225	2.17e-87	269.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_346615_2	1380600.AUYN01000009_gene1920	6.5e-150	432.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
k59_1532795_1	365044.Pnap_0464	2.38e-101	298.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
k59_1476636_1	1380600.AUYN01000009_gene2145	0.0	903.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1HWQ0@117743|Flavobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1476636_2	1137281.D778_01174	3.94e-44	155.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1HXUH@117743|Flavobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_1363041_1	1392489.JPOL01000002_gene1284	4.14e-84	278.0	COG0823@1|root,COG4677@1|root,COG5276@1|root,COG0823@2|Bacteria,COG4677@2|Bacteria,COG5276@2|Bacteria,4PNFN@976|Bacteroidetes,1I0J5@117743|Flavobacteriia	976|Bacteroidetes	G	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,TSP_3
k59_234620_1	90814.KL370892_gene2261	1.86e-124	367.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,460A1@72273|Thiotrichales	72273|Thiotrichales	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_234620_2	90814.KL370892_gene2262	1.07e-148	431.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,46042@72273|Thiotrichales	72273|Thiotrichales	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_629764_1	1492738.FEM21_10310	1.56e-135	401.0	COG0702@1|root,COG0702@2|Bacteria,4NG5U@976|Bacteroidetes,1I0T9@117743|Flavobacteriia,2NT3H@237|Flavobacterium	976|Bacteroidetes	GM	Carbohydrate-binding protein SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_629764_2	1392489.JPOL01000002_gene1285	2.09e-175	506.0	2C0TP@1|root,2Z7QF@2|Bacteria,4NGXF@976|Bacteroidetes,1HYWB@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4957,DUF5123,fn3
k59_1025301_1	326298.Suden_1155	1.05e-40	142.0	COG1227@1|root,COG1227@2|Bacteria,1P9JN@1224|Proteobacteria,42N0W@68525|delta/epsilon subdivisions,2YNNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
k59_1025301_2	944547.ABLL_2037	5.2e-58	202.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_516300_1	572480.Arnit_1332	1.11e-10	61.2	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_516300_2	572480.Arnit_1331	1.59e-102	317.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PilJ,SBP_bac_3,dCache_2,dCache_3
k59_1590300_1	688270.Celal_1791	1.04e-135	404.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1590300_2	1121007.AUML01000017_gene396	2.16e-47	160.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1HZF4@117743|Flavobacteriia,2YKNX@290174|Aquimarina	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
k59_64982_1	1121931.AUHG01000010_gene227	8.05e-67	207.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1HY5F@117743|Flavobacteriia	976|Bacteroidetes	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_1646619_1	1348657.M622_09710	4.67e-32	124.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,2VPEA@28216|Betaproteobacteria,2KXIP@206389|Rhodocyclales	206389|Rhodocyclales	O	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
k59_1532831_1	572480.Arnit_2626	3.47e-39	140.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2YMA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1646624_1	1283340.Q6WHU9_BPKVM	2.37e-24	96.7	4QB0E@10239|Viruses,4QXJE@35237|dsDNA viruses  no RNA stage,4QQU3@28883|Caudovirales,4QI46@10662|Myoviridae	10662|Myoviridae	S	Pyrimidine dimer DNA glycosylase	-	GO:0000704,GO:0003674,GO:0003824,GO:0003906,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0140097	-	-	-	-	-	-	-	-	-	-	-
k59_1137541_1	1380600.AUYN01000006_gene348	0.0	1182.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_460573_1	1380600.AUYN01000001_gene2221	2.39e-144	418.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1HWPT@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_460573_2	1380600.AUYN01000001_gene2220	1.57e-126	361.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1HXVV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_460573_3	1434325.AZQN01000005_gene3520	3.55e-10	59.7	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,47JWF@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_742377_1	521719.ATXQ01000001_gene408	1.37e-13	72.8	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1YE42@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_742377_2	269799.Gmet_2868	1.84e-45	154.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,43U24@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
k59_1702934_1	1026882.MAMP_00551	1.81e-25	110.0	COG5635@1|root,COG5635@2|Bacteria,1MY1P@1224|Proteobacteria,1RZKH@1236|Gammaproteobacteria,46348@72273|Thiotrichales	72273|Thiotrichales	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_855084_1	317025.Tcr_0946	3.75e-71	229.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,461P8@72273|Thiotrichales	72273|Thiotrichales	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
k59_460587_1	317025.Tcr_0524	6.45e-66	218.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,4635K@72273|Thiotrichales	72273|Thiotrichales	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_305301_1	857087.Metme_0461	7.47e-78	241.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XDZI@135618|Methylococcales	135618|Methylococcales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_869791_1	1304885.AUEY01000003_gene534	5.69e-23	101.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42TBQ@68525|delta/epsilon subdivisions,2WPWC@28221|Deltaproteobacteria,2MPSG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_756074_1	1353528.DT23_12105	3.82e-119	348.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,2XKQS@285107|Thioclava	28211|Alphaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1661163_1	323850.Shew_1777	2.48e-58	193.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,2Q9AY@267890|Shewanellaceae	1236|Gammaproteobacteria	EGP	TIGRFAM drug resistance transporter, Bcr CflA subfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_1661163_2	323850.Shew_1780	2.99e-11	62.8	COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,1S3TT@1236|Gammaproteobacteria,2Q8KG@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N_3
k59_21460_1	1121931.AUHG01000011_gene2370	1.99e-25	103.0	2C95T@1|root,2Z7NG@2|Bacteria,4NGVW@976|Bacteroidetes,1HZNE@117743|Flavobacteriia	976|Bacteroidetes	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
k59_1433950_1	1239962.C943_01648	1.09e-164	472.0	COG5309@1|root,COG5309@2|Bacteria,4NFD7@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_1774456_1	1237149.C900_04019	6.16e-73	235.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,47JTP@768503|Cytophagia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1039377_1	1123228.AUIH01000028_gene460	3.25e-81	250.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XHTC@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_475171_1	1121931.AUHG01000011_gene1709	1.97e-126	365.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_475171_2	1121931.AUHG01000011_gene1708	7.55e-140	395.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1HWWF@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_475171_3	411154.GFO_2816	1.17e-83	248.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1323054_1	1506583.JQJY01000002_gene1805	1.58e-198	556.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,1I0YN@117743|Flavobacteriia,2NVAI@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
k59_756109_1	419947.MRA_2234	1.46e-31	122.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,236CU@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_814430_1	1469557.JSWF01000025_gene1337	3.42e-61	191.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1I1AB@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_814430_2	1380600.AUYN01000001_gene2680	5.37e-173	486.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1HXPC@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_814430_3	1380600.AUYN01000001_gene2679	2.49e-180	507.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1HWMA@117743|Flavobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_814430_4	1380600.AUYN01000001_gene2678	9.76e-135	406.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1151031_1	242619.PG_0334	3.12e-29	113.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,2FMW6@200643|Bacteroidia,22Y10@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k59_1151031_2	983544.Lacal_1786	2.22e-180	529.0	2DG4M@1|root,2ZUGM@2|Bacteria,4NPD9@976|Bacteroidetes,1I7MC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1202718_1	1223410.KN050846_gene2836	4.75e-11	62.4	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
k59_1202718_2	1391646.AVSU01000099_gene344	5.35e-13	73.2	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25SBR@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
k59_644389_1	1249975.JQLP01000005_gene523	5.67e-179	511.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2P615@244698|Gillisia	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_1433996_1	572480.Arnit_1246	2.5e-82	263.0	COG2197@1|root,COG2200@1|root,COG2197@2|Bacteria,COG2200@2|Bacteria,1N299@1224|Proteobacteria,42NV9@68525|delta/epsilon subdivisions,2YMSB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PAS_3,PAS_9,Response_reg
k59_701901_1	411154.GFO_2730	4.95e-11	61.6	COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,1HY8V@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_701901_2	411154.GFO_2729	3.74e-150	424.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,1HXTK@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
k59_925646_1	944547.ABLL_0443	3.74e-37	138.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_925646_2	944547.ABLL_0442	6.07e-66	206.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2YMFW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_249398_1	1238450.VIBNISOn1_1210006	8.63e-88	270.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_21522_1	744979.R2A130_1248	2.46e-56	198.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1039424_1	1380600.AUYN01000007_gene3190	7.5e-175	495.0	COG0787@1|root,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1HWKS@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
k59_1039424_2	1250232.JQNJ01000001_gene1161	6.06e-68	208.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
k59_756149_1	313603.FB2170_14808	5.38e-145	420.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Pyr_redox_3
k59_756149_2	313603.FB2170_14813	2.1e-46	165.0	COG0484@1|root,COG0484@2|Bacteria,4P0AH@976|Bacteroidetes	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_814469_1	525898.Sdel_1163	1.17e-79	246.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42PBT@68525|delta/epsilon subdivisions,2YN9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_814469_2	1151292.QEW_2967	1.24e-29	110.0	COG4925@1|root,COG4925@2|Bacteria,1V9AI@1239|Firmicutes,24PAJ@186801|Clostridia	186801|Clostridia	I	sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclophil_like
k59_1151073_1	243231.GSU1269	7.38e-75	252.0	COG1470@1|root,COG5276@1|root,COG1470@2|Bacteria,COG5276@2|Bacteria,1NTT8@1224|Proteobacteria,42ZD4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
k59_1094724_1	1380600.AUYN01000009_gene2061	3.34e-201	574.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_305397_1	1353276.JADR01000006_gene1236	3.18e-250	694.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia	976|Bacteroidetes	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_305397_2	1469557.JSWF01000019_gene234	2.16e-125	372.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_978572_1	367737.Abu_0302	1.11e-44	162.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YP45@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1434032_1	1123228.AUIH01000003_gene843	3.81e-96	295.0	COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,1XIJP@135619|Oceanospirillales	135619|Oceanospirillales	EK	transcriptional regulator	-	-	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	PAS,PAS_8,Sigma54_activ_2,Sigma54_activat
k59_1546756_1	1168067.JAGP01000001_gene248	2.78e-59	185.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,460RJ@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_1546756_2	1123518.ARWI01000001_gene1047	7.16e-33	118.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,460IU@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_531162_1	926559.JoomaDRAFT_3847	9.79e-101	315.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1HZSK@117743|Flavobacteriia	976|Bacteroidetes	P	sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_305427_1	1121931.AUHG01000010_gene462	1.77e-57	197.0	COG2755@1|root,COG2755@2|Bacteria,4NKE5@976|Bacteroidetes,1HXIM@117743|Flavobacteriia	976|Bacteroidetes	E	Rhamnogalacturonan acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Pec_lyase
k59_79836_1	1454202.PPBDW_10010___1	5.1e-71	229.0	COG2131@1|root,COG2131@2|Bacteria,1QDAH@1224|Proteobacteria,1RRDW@1236|Gammaproteobacteria,1XX7Y@135623|Vibrionales	135623|Vibrionales	F	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
k59_418296_1	504487.JCM19302_224	1.81e-50	172.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_418296_2	1121912.AUHD01000019_gene3417	2.08e-122	353.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_1377269_1	1347342.BN863_20530	1.15e-164	476.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1323169_1	1123228.AUIH01000032_gene1730	1.99e-55	195.0	COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales	135619|Oceanospirillales	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
k59_134982_1	326298.Suden_1450	2.3e-84	271.0	COG3206@1|root,COG3206@2|Bacteria,1Q26P@1224|Proteobacteria,42V2K@68525|delta/epsilon subdivisions,2YQ9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1151134_1	929558.SMGD1_0798	2.27e-100	313.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1151134_2	563040.Saut_1783	1.47e-73	223.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1151134_3	326298.Suden_0424	1.36e-24	100.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2YMR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_644485_1	90813.JQMT01000001_gene788	4.33e-58	195.0	COG2199@1|root,COG3706@2|Bacteria,1N6SR@1224|Proteobacteria,1T2CM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_475296_1	1249975.JQLP01000005_gene610	1.97e-81	261.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1I0PJ@117743|Flavobacteriia,2P79A@244698|Gillisia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_1323177_1	1121897.AUGO01000008_gene2688	1.09e-40	144.0	2A9M0@1|root,30YTK@2|Bacteria,4PCRD@976|Bacteroidetes,1ID9W@117743|Flavobacteriia,2NXU4@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1323177_2	362418.IW19_20885	1.25e-59	188.0	COG0662@1|root,COG0662@2|Bacteria,4NQHH@976|Bacteroidetes,1I36H@117743|Flavobacteriia,2NVWP@237|Flavobacterium	976|Bacteroidetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_1323177_3	1392490.JHZX01000001_gene2039	2.68e-84	269.0	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,1HWVG@117743|Flavobacteriia	976|Bacteroidetes	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pec_lyase,Pectinesterase
k59_814557_1	90814.KL370891_gene1365	3.9e-49	160.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,460WW@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_814557_2	90814.KL370891_gene1364	5.19e-86	257.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,4609I@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_978617_1	180281.CPCC7001_173	0.000471	42.4	COG1283@1|root,COG1283@2|Bacteria,1G2NY@1117|Cyanobacteria	1117|Cyanobacteria	P	Na Pi-cotransporter family protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
k59_135009_1	1178825.ALIH01000001_gene2389	3.36e-25	99.8	28QB8@1|root,2ZCTU@2|Bacteria,4NP7R@976|Bacteroidetes,1I1M5@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
k59_135009_2	504487.JCM19302_3216	5.95e-47	159.0	COG1215@1|root,COG1215@2|Bacteria,4PKAP@976|Bacteroidetes,1IJ5R@117743|Flavobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate beta-D-mannosyltransferase	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_978620_1	1123518.ARWI01000001_gene2411	1.3e-157	458.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461JQ@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_1265083_1	1232410.KI421422_gene2035	7.37e-94	287.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,43RXU@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_79895_1	748247.AZKH_4264	1.74e-32	124.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria,2KV76@206389|Rhodocyclales	206389|Rhodocyclales	I	Long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_79895_2	305700.B447_16894	1.82e-73	222.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,2KWTN@206389|Rhodocyclales	206389|Rhodocyclales	I	Thioesterase superfamily	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k59_418340_1	411154.GFO_3396	2.35e-110	345.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mexF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_531263_2	504487.JCM19302_4255	3.69e-07	50.4	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1774659_1	1121904.ARBP01000017_gene5127	7.89e-27	105.0	2DP7Y@1|root,330X4@2|Bacteria,4NUP0@976|Bacteroidetes,47XV3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1546860_1	391603.FBALC1_10962	1.81e-61	216.0	COG1361@1|root,COG2304@1|root,COG3209@1|root,COG4257@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4257@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
k59_1546860_2	1178825.ALIH01000002_gene832	1.69e-142	408.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1323229_1	1484460.JSWG01000004_gene2659	2.39e-124	357.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_644551_1	1121875.KB907552_gene249	4.41e-312	872.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_81850_3	929558.SMGD1_0730	4.71e-43	145.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2YMTM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_1663314_1	1178825.ALIH01000006_gene1508	1.17e-63	202.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,1I1SW@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
k59_1663314_2	1122225.AULQ01000001_gene1673	4.3e-105	318.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,1HXNZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_137072_1	504487.JCM19302_4001	7.08e-148	424.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1HYD7@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_1607835_1	1349785.BAUG01000004_gene295	3.91e-18	81.3	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,1HX0G@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1607835_2	1121931.AUHG01000010_gene636	1.37e-102	311.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,1HYWP@117743|Flavobacteriia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase domain protein	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
k59_1096932_1	1197477.IA57_00865	1.35e-56	182.0	2D59T@1|root,32TIK@2|Bacteria,4NNIG@976|Bacteroidetes,1I44A@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
k59_1096932_2	1380600.AUYN01000009_gene1631	3.42e-14	69.3	28P9K@1|root,2ZC31@2|Bacteria,4NPW6@976|Bacteroidetes,1I1KA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
k59_477393_1	1237149.C900_03097	5.85e-103	332.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_1267107_1	572480.Arnit_2735	1.15e-92	289.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_307525_1	1380600.AUYN01000009_gene1906	7.57e-119	349.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,1HYDA@117743|Flavobacteriia	976|Bacteroidetes	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_195003_1	1286093.C266_06274	5.5e-101	304.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VJXD@28216|Betaproteobacteria,1JZY8@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	PFAM General substrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_477407_1	929558.SMGD1_1831	8.03e-121	356.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2YNID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acid membrane antigen A	amaA	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_548299_2	1123518.ARWI01000001_gene91	1.09e-160	459.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,45ZXT@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
k59_1511407_1	655815.ZPR_4535	4.44e-16	82.8	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_379489_1	1406840.Q763_06825	9.95e-56	185.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,2NUFQ@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1736563_2	929558.SMGD1_2614	2.84e-78	240.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_775086_1	561231.Pecwa_0997	4.03e-56	207.0	COG1629@1|root,COG1629@2|Bacteria,1QV18@1224|Proteobacteria,1T2Q3@1236|Gammaproteobacteria,1MU03@122277|Pectobacterium	1236|Gammaproteobacteria	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
k59_775086_2	225849.swp_2084	3.04e-10	61.6	COG0457@1|root,COG4932@1|root,COG0457@2|Bacteria,COG4932@2|Bacteria,1R93G@1224|Proteobacteria,1S0TE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1342710_1	1232410.KI421426_gene1359	5.09e-122	384.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,43SE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_39933_4	1395516.PMO01_17415	1.6e-71	232.0	2F7JT@1|root,3400E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1623843_1	572480.Arnit_0942	8.7e-136	394.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YMH1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1623843_2	944547.ABLL_0828	2.19e-72	221.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2YNVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_98994_1	392500.Swoo_3237	1.56e-24	96.3	COG2916@1|root,COG2916@2|Bacteria,1R9YM@1224|Proteobacteria,1S24H@1236|Gammaproteobacteria,2QBWE@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the histone-like protein H-NS family	hns	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0043900,GO:0043901,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1900190,GO:1900191,GO:1900231,GO:1900232,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03746,ko:K11685	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
k59_98994_2	1515746.HR45_18560	2.96e-14	70.5	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,2Q945@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_604547_1	1121931.AUHG01000011_gene2271	9.15e-142	407.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1HX9B@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_1170742_1	1209072.ALBT01000035_gene1454	2.31e-136	396.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1FHYA@10|Cellvibrio	1236|Gammaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_1216116_1	411154.GFO_3053	1.41e-141	410.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_722512_1	357804.Ping_1883	1.51e-57	199.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Pfam SNARE associated Golgi protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
k59_1680061_1	391603.FBALC1_12237	1.4e-49	176.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_1680061_2	1123037.AUDE01000020_gene3517	1.74e-16	79.7	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_493951_1	460265.Mnod_6237	1.15e-57	194.0	COG2369@1|root,COG2369@2|Bacteria,1P87U@1224|Proteobacteria,2TSNA@28211|Alphaproteobacteria,1JYRQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	head morphogenesis protein SPP1 gp7	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_1216126_1	1406840.Q763_00335	1.36e-116	365.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia,2P0JG@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_99004_1	1380600.AUYN01000001_gene2336	8.47e-103	305.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1HX36@117743|Flavobacteriia	976|Bacteroidetes	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_99004_2	398720.MED217_10737	2.52e-60	203.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia,2XIFZ@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Polyphosphate kinase middle domain	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1170753_1	335543.Sfum_2126	5.38e-36	127.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2MRQA@213462|Syntrophobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
k59_1170753_2	696281.Desru_2822	1.1e-17	78.6	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,2593B@186801|Clostridia,2628M@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_267492_1	1380600.AUYN01000001_gene2920	9.36e-85	256.0	COG3642@1|root,COG3642@2|Bacteria,4NIJK@976|Bacteroidetes,1HZEK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Lipopolysaccharide kinase (Kdo WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_39958_1	1123518.ARWI01000001_gene996	3.09e-31	117.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1S29P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
k59_39958_2	1123518.ARWI01000001_gene997	2.55e-102	314.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,460GN@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
k59_493971_1	929558.SMGD1_2847	3.74e-66	214.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2YMX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1793885_1	572480.Arnit_2113	2.04e-65	199.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	ninG	-	-	-	-	-	-	-	-	-	-	-	NinG
k59_1170766_1	563040.Saut_1512	1.92e-82	251.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42YQZ@68525|delta/epsilon subdivisions,2YREH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1170766_2	563040.Saut_1956	7.54e-42	155.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_379547_1	485918.Cpin_3951	3.97e-51	184.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1INVS@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_379547_2	391603.FBALC1_07723	2.41e-26	97.4	2E3TF@1|root,32YQY@2|Bacteria,4NUMK@976|Bacteroidetes,1I52K@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1342778_1	1348657.M622_03210	2.7e-49	163.0	28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,2VRKU@28216|Betaproteobacteria,2KWW0@206389|Rhodocyclales	206389|Rhodocyclales	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
k59_1284124_1	929558.SMGD1_1970	3.44e-16	75.9	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2YNDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_1284124_2	929558.SMGD1_1971	1.02e-101	304.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2YREW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_211908_2	1137281.D778_01805	4.2e-195	557.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1342787_1	267608.RSc3218	1.1e-90	283.0	28IJM@1|root,2Z8KG@2|Bacteria,1R9N3@1224|Proteobacteria,2VNIK@28216|Betaproteobacteria,1K3FS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1736678_1	317025.Tcr_1368	3.44e-35	135.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,4607H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_1736678_2	1122134.KB893651_gene2418	1.12e-31	118.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XJ9Q@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_267540_2	1537994.JQFW01000015_gene1331	8.36e-50	162.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,1S45M@1236|Gammaproteobacteria,466TZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Metal-dependent hydrolase	ygjP	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1736683_1	1122605.KB893646_gene25	1.7e-49	181.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IRE6@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_1342816_1	1123514.KB905899_gene850	1.97e-100	312.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent Clp protease ATP-binding subunit ClpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1056694_1	697303.Thewi_2363	5.34e-54	193.0	COG0784@1|root,COG2199@1|root,COG3290@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,42FTQ@68295|Thermoanaerobacterales	186801|Clostridia	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,GGDEF,PAS,PAS_8,PAS_9,Response_reg
k59_996928_1	1168065.DOK_14294	7.34e-41	145.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1J5SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	ramA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1114164_1	298386.PBPRA1265	8.55e-242	682.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1XUC7@135623|Vibrionales	135623|Vibrionales	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_775233_1	1123514.KB905899_gene1323	2.51e-174	503.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,46047@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_775238_1	572480.Arnit_2050	3.82e-79	238.0	COG2128@1|root,COG2128@2|Bacteria,1P0CZ@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1342842_1	411154.GFO_0741	5.03e-35	128.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1HYWH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
k59_1342842_2	1121931.AUHG01000016_gene1015	2.96e-52	171.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1HXVN@117743|Flavobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_99137_1	626887.J057_14680	2.15e-74	246.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,4648S@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1623950_1	572480.Arnit_2616	1.63e-34	130.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_888863_1	1120966.AUBU01000005_gene3846	1.79e-45	156.0	COG2207@1|root,COG2207@2|Bacteria,4NRBA@976|Bacteroidetes,47RNM@768503|Cytophagia	976|Bacteroidetes	K	helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_154061_1	1172190.M947_10870	1.1e-93	294.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1284236_1	1137281.D778_01815	1.06e-297	829.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_1170901_2	1178825.ALIH01000007_gene1623	3.89e-263	728.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
k59_326939_2	926559.JoomaDRAFT_2732	4.16e-37	129.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,1I1TM@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1116352_2	649747.HMPREF0083_05146	9.12e-35	122.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,26XQC@186822|Paenibacillaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_666155_1	90814.KL370891_gene493	1.08e-41	150.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,45ZN8@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_666155_2	1123518.ARWI01000001_gene826	1.61e-62	201.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,45ZWD@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1796170_1	1172190.M947_02395	4e-78	261.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1MXA3@1224|Proteobacteria,43ANN@68525|delta/epsilon subdivisions,2YT2I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EPT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1796170_2	929558.SMGD1_1297	4.3e-17	80.1	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_999215_1	1123518.ARWI01000001_gene798	4.43e-103	310.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,45ZQZ@72273|Thiotrichales	72273|Thiotrichales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
k59_1682397_1	1178825.ALIH01000005_gene350	1.16e-227	629.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1HY4I@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1682397_2	1137281.D778_02512	5.24e-236	662.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia	976|Bacteroidetes	O	Molecular chaperone	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_999237_1	572480.Arnit_3143	9.02e-98	298.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42N7Z@68525|delta/epsilon subdivisions,2YN64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1513822_1	411154.GFO_2950	2.59e-74	234.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,1HXSD@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_101434_1	323848.Nmul_A1709	1.46e-15	86.7	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,372SX@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,dCache_1
k59_327044_1	317025.Tcr_1244	2.35e-133	397.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,461JH@72273|Thiotrichales	72273|Thiotrichales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_1116472_1	930171.Asphe3_02470	7.86e-05	44.7	COG0642@1|root,COG2205@2|Bacteria,2I5TZ@201174|Actinobacteria,1WBHJ@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
k59_1116472_2	1250232.JQNJ01000001_gene3059	7.81e-50	166.0	COG0745@1|root,COG0745@2|Bacteria,4NMAC@976|Bacteroidetes,1I1ST@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_156028_1	411154.GFO_1645	1.47e-217	602.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_156028_2	1121931.AUHG01000012_gene2532	1.03e-29	111.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1HY0K@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1059026_1	326298.Suden_0281	1.52e-32	125.0	COG4191@1|root,COG4753@1|root,COG4191@2|Bacteria,COG4753@2|Bacteria,1RCM9@1224|Proteobacteria,42R06@68525|delta/epsilon subdivisions,2YP00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_1059026_2	929558.SMGD1_0996	1.42e-58	186.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2YP63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_1739199_1	411154.GFO_0360	8.4e-83	270.0	COG2197@1|root,COG3292@1|root,COG2197@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1513858_2	563040.Saut_0279	8.89e-103	305.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42PRV@68525|delta/epsilon subdivisions,2YTQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Transport permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
k59_550618_1	1123228.AUIH01000003_gene870	3.49e-21	94.0	COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1XK72@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
k59_777744_2	926562.Oweho_2538	7.52e-34	131.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1HWW3@117743|Flavobacteriia,2PAWC@246874|Cryomorphaceae	976|Bacteroidetes	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1345303_1	1172190.M947_01995	6.26e-30	119.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_1568100_1	90814.KL370891_gene1498	6.18e-14	66.2	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	cycM	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1568100_2	1286106.MPL1_06717	5.24e-35	133.0	COG0247@1|root,COG0277@1|root,COG0437@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0437@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1527827_1	1117958.PE143B_0107960	1.14e-35	141.0	COG2199@1|root,COG3706@2|Bacteria,1RC1J@1224|Proteobacteria,1S2CD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS,PAS_3,PAS_9
k59_793632_1	411154.GFO_1581	2.13e-80	249.0	COG0628@1|root,COG0628@2|Bacteria,4NFB2@976|Bacteroidetes,1HZR1@117743|Flavobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_849488_1	1484460.JSWG01000008_gene1980	8.67e-74	232.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1HWKX@117743|Flavobacteriia	976|Bacteroidetes	GM	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_2953_1	1178825.ALIH01000010_gene467	8.8e-107	317.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1075419_1	563040.Saut_1659	3.86e-70	218.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2YN8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1075419_2	929558.SMGD1_0759	3.65e-53	172.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2YPHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1697441_1	411154.GFO_3410	2.18e-95	285.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1358024_1	1347342.BN863_34730	1.03e-66	220.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,4NDVW@976|Bacteroidetes,1HXBF@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome C biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_1753999_1	522306.CAP2UW1_2047	5.36e-14	70.5	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,1KPQD@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1753999_2	748247.AZKH_1024	4.1e-51	165.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,2KW5B@206389|Rhodocyclales	206389|Rhodocyclales	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k59_1641184_1	1353276.JADR01000002_gene2067	2.48e-112	335.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
k59_1075432_1	1165841.SULAR_05018	2.14e-71	221.0	COG0110@1|root,COG0110@2|Bacteria,1NFMZ@1224|Proteobacteria,43AWQ@68525|delta/epsilon subdivisions,2YT3X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	2.3.1.209	ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
k59_1075432_2	1123517.JOMR01000001_gene1331	4.16e-204	571.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RQ7S@1236|Gammaproteobacteria,460D1@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1075432_3	1123517.JOMR01000001_gene1332	4.6e-20	88.2	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,461CW@72273|Thiotrichales	72273|Thiotrichales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_963010_1	1178825.ALIH01000003_gene2166	1.52e-247	683.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1HWXE@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_963010_3	1197477.IA57_05835	3.57e-85	254.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1I19R@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_1584539_1	1089547.KB913013_gene4668	5.91e-127	394.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_454919_1	1178825.ALIH01000001_gene2512	6.9e-165	472.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
k59_1358048_2	944547.ABLL_2314	4.54e-65	228.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,SBP_bac_3
k59_1754041_1	1121931.AUHG01000015_gene1237	2.84e-107	325.0	28IKH@1|root,2Z8M8@2|Bacteria,4NFVI@976|Bacteroidetes,1HWNR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1754041_2	411154.GFO_0521	3.25e-16	74.7	2C5ER@1|root,31U66@2|Bacteria,4NP5G@976|Bacteroidetes,1I242@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_624328_1	411154.GFO_2343	1.7e-192	549.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia	976|Bacteroidetes	O	Molecular chaperone	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_510729_1	1121931.AUHG01000018_gene1329	1.48e-120	373.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_341381_1	563040.Saut_1705	2.68e-08	55.1	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VD0@68525|delta/epsilon subdivisions,2YQ93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_341381_2	929558.SMGD1_1867	1.75e-68	214.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2YM87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_1019796_1	1353276.JADR01000008_gene887	1.96e-86	265.0	COG0845@1|root,COG0845@2|Bacteria,4NMQS@976|Bacteroidetes,1I1M7@117743|Flavobacteriia	976|Bacteroidetes	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_454950_1	1123518.ARWI01000001_gene2445	2.1e-141	404.0	COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_454950_2	90814.KL370891_gene1282	3.55e-36	124.0	2CC8C@1|root,2ZKKN@2|Bacteria,1P7RM@1224|Proteobacteria,1SURG@1236|Gammaproteobacteria,4639P@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_793713_1	991.IW20_20460	1.23e-113	331.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1HXEE@117743|Flavobacteriia,2NUBV@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_228944_1	1249975.JQLP01000008_gene318	1.15e-75	240.0	28M6U@1|root,2ZAKE@2|Bacteria,4NM2W@976|Bacteroidetes,1HZQX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1358075_1	411154.GFO_1875	1.48e-168	482.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1HYHI@117743|Flavobacteriia	976|Bacteroidetes	J	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_793715_2	1484460.JSWG01000011_gene1795	1.21e-107	312.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1HXQM@117743|Flavobacteriia	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_793715_3	1380600.AUYN01000001_gene2354	1.2e-28	112.0	2CDHR@1|root,341P0@2|Bacteria,4P49J@976|Bacteroidetes,1I9WB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_341400_1	1406840.Q763_09765	4.8e-102	296.0	2EKSA@1|root,33EG2@2|Bacteria,4NYRG@976|Bacteroidetes,1I8JD@117743|Flavobacteriia,2NXS8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_963061_1	411154.GFO_2521	3.07e-142	428.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1527923_1	428127.EUBDOL_01726	1.88e-25	102.0	COG5017@1|root,COG5017@2|Bacteria,1VBCS@1239|Firmicutes,3VRJ1@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Glycosyltransferase family 28 C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_59541_1	1121931.AUHG01000010_gene732	1.92e-60	189.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1HWX6@117743|Flavobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_59541_2	1121931.AUHG01000010_gene733	8.38e-21	90.5	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia	976|Bacteroidetes	M	probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_398426_1	1123518.ARWI01000001_gene2044	5.8e-49	159.0	COG2246@1|root,COG2246@2|Bacteria,1RJUK@1224|Proteobacteria,1SAXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k59_398426_2	1123514.KB905899_gene444	3.46e-114	335.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,1RZUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
k59_60830_1	1380600.AUYN01000009_gene1919	8.85e-243	694.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1416342_1	243090.RB4179	1.02e-32	130.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,2IY6A@203682|Planctomycetes	203682|Planctomycetes	T	Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat
k59_1246317_1	1123518.ARWI01000001_gene1474	1.31e-229	647.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,45ZXV@72273|Thiotrichales	72273|Thiotrichales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1246317_2	1123514.KB905902_gene316	1.73e-64	201.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,461BM@72273|Thiotrichales	72273|Thiotrichales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_1246317_3	317025.Tcr_2199	1.68e-20	81.6	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,461EJ@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k59_1246317_4	317025.Tcr_2201	1.07e-28	110.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,4610S@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1642605_1	1178825.ALIH01000003_gene2249	6.85e-22	94.7	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1HYZ4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_1076773_1	983544.Lacal_0469	3.62e-122	376.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HY96@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_1133869_1	326298.Suden_0711	2.45e-127	372.0	COG2374@1|root,COG2374@2|Bacteria,1RCTI@1224|Proteobacteria,42Q2J@68525|delta/epsilon subdivisions,2YNG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1246334_1	563040.Saut_1469	5.09e-78	258.0	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_4272_1	640081.Dsui_1895	4.61e-17	81.6	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,2KYIA@206389|Rhodocyclales	206389|Rhodocyclales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_625666_1	1380600.AUYN01000009_gene1713	7.89e-258	723.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_625666_2	1178825.ALIH01000010_gene397	7.74e-90	275.0	COG3832@1|root,COG4978@1|root,COG3832@2|Bacteria,COG4978@2|Bacteria,4NFPM@976|Bacteroidetes,1HYM3@117743|Flavobacteriia	976|Bacteroidetes	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,GyrI-like,Polyketide_cyc2
k59_342682_2	349521.HCH_05216	1.13e-53	175.0	COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,1XIVV@135619|Oceanospirillales	135619|Oceanospirillales	E	amino acid ABC transporter	-	-	-	ko:K10015,ko:K10023	ko02010,map02010	M00225,M00226,M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1,3.A.1.3.11	-	-	BPD_transp_1
k59_230414_1	572480.Arnit_2358	4.15e-22	88.2	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2YPGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_230414_2	572480.Arnit_2359	2.06e-59	199.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1021214_1	929558.SMGD1_1975	1.14e-102	303.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2YMER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_342687_1	1121931.AUHG01000019_gene3051	1.45e-102	307.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1HYZG@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_568973_1	504487.JCM19302_16	1.01e-17	79.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_568973_2	1161401.ASJA01000018_gene1174	3.98e-16	76.6	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2,SnoaL_4
k59_1303871_1	1123518.ARWI01000001_gene388	1.37e-116	358.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,461R1@72273|Thiotrichales	72273|Thiotrichales	O	Belongs to the peptidase S16 family	-	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_738678_1	563040.Saut_2096	3.49e-56	189.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42PRR@68525|delta/epsilon subdivisions,2YMYP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	sulfur dehydrogenase subunit	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_625687_1	717231.Flexsi_0312	9.5e-70	229.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2GGDY@200930|Deferribacteres	200930|Deferribacteres	P	Adenylylsulphate kinase	-	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k59_1755511_1	1172190.M947_05035	4.07e-115	338.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N5U@68525|delta/epsilon subdivisions,2YMNF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_4292_1	1123514.KB905899_gene1934	4.87e-113	333.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,4612J@72273|Thiotrichales	72273|Thiotrichales	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_60889_1	349102.Rsph17025_0112	1.44e-18	85.1	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2U05W@28211|Alphaproteobacteria,1FD3Z@1060|Rhodobacter	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
k59_850930_1	1121931.AUHG01000011_gene2126	1.12e-89	276.0	COG1225@1|root,COG1225@2|Bacteria,4NH32@976|Bacteroidetes,1HWQJ@117743|Flavobacteriia	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
k59_286773_2	1121912.AUHD01000016_gene2925	0.0	1128.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_286773_4	391603.FBALC1_09432	5.41e-118	362.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_399844_1	1380600.AUYN01000009_gene1482	1.75e-53	174.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1HYYA@117743|Flavobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_399844_2	1380600.AUYN01000009_gene1483	5.97e-108	320.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1189733_1	317025.Tcr_0039	1.13e-112	325.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,1S50T@1236|Gammaproteobacteria,4626D@72273|Thiotrichales	72273|Thiotrichales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_1529180_1	411154.GFO_2056	3.87e-83	258.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucosamine mutase	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1529180_2	1121931.AUHG01000011_gene2309	4.36e-18	79.3	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
k59_4305_1	1123367.C666_13235	1.65e-68	215.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,2KW55@206389|Rhodocyclales	206389|Rhodocyclales	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_569005_1	1178825.ALIH01000001_gene2476	1.72e-28	112.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
k59_569005_2	1250006.JHZZ01000001_gene3360	3.89e-117	340.0	COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,1HX4N@117743|Flavobacteriia,3VWA3@52959|Polaribacter	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_795261_1	946077.W5A_07712	3.33e-15	73.6	COG4667@1|root,COG4667@2|Bacteria,4NF0K@976|Bacteroidetes,1HX96@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_795261_2	504487.JCM19302_2844	5.04e-59	201.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_456447_1	1178825.ALIH01000001_gene2263	1.75e-126	401.0	COG1345@1|root,COG1361@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3291@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_512211_1	1123514.KB905899_gene635	3.26e-141	412.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4604A@72273|Thiotrichales	72273|Thiotrichales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_850964_1	1123514.KB905902_gene218	2.25e-54	175.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,460YS@72273|Thiotrichales	72273|Thiotrichales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_850964_2	1123518.ARWI01000001_gene1351	6.81e-22	94.7	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_908092_1	1172190.M947_06560	5.93e-53	186.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_908092_2	929558.SMGD1_0812	3.56e-125	380.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_60934_1	509635.N824_11005	3.29e-68	240.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1IUY8@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1539886_1	1123518.ARWI01000001_gene2155	7.44e-207	582.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_749491_1	411154.GFO_3548	3.72e-12	65.1	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_749491_2	1121931.AUHG01000010_gene577	7.04e-57	177.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1I5R2@117743|Flavobacteriia	976|Bacteroidetes	C	COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit)	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_749491_3	1121931.AUHG01000010_gene579	5.59e-32	124.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_242109_1	929558.SMGD1_0046	3.47e-81	249.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_242109_2	929558.SMGD1_0028	3.37e-43	151.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2YNG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1144376_1	1380600.AUYN01000012_gene2985	4.36e-55	179.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,1HYVJ@117743|Flavobacteriia	976|Bacteroidetes	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
k59_1144376_2	1250005.PHEL85_0198	3.33e-161	456.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia,3VVHE@52959|Polaribacter	976|Bacteroidetes	F	Phosphorylase superfamily	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_1144376_3	1137281.D778_00808	1.16e-83	256.0	2DBAY@1|root,2Z84S@2|Bacteria,4NGXD@976|Bacteroidetes,1HXHD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
k59_1032360_1	326298.Suden_2096	2.13e-122	371.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1710529_1	1469557.JSWF01000025_gene1352	1.38e-293	820.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1HZ7E@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_973277_1	1121931.AUHG01000012_gene2820	3.8e-78	242.0	COG3391@1|root,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,1HYX0@117743|Flavobacteriia	976|Bacteroidetes	G	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_72578_1	1172190.M947_06025	6.09e-111	325.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_468009_1	1232410.KI421421_gene3649	7.62e-97	294.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,42PFR@68525|delta/epsilon subdivisions,2WJUB@28221|Deltaproteobacteria,43S36@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1427329_2	1168067.JAGP01000001_gene1387	4e-53	168.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,460ZC@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_1427329_3	1123518.ARWI01000001_gene2264	2.84e-139	412.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1370267_1	62928.azo3048	1.86e-109	323.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VK9Y@28216|Betaproteobacteria,2KV1M@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1539933_1	90813.JQMT01000001_gene1387	1.21e-107	327.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_242165_1	1121931.AUHG01000010_gene805	1.7e-119	351.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HWPQ@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1370301_1	1168067.JAGP01000001_gene767	4.34e-06	48.1	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,1RRFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	General glycosylation pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1370301_2	1168067.JAGP01000001_gene768	1.86e-117	343.0	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,460RR@72273|Thiotrichales	72273|Thiotrichales	S	HAD-superfamily hydrolase, subfamily IIB	-	-	2.7.1.31,3.1.3.70	ko:K07026,ko:K15918	ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200	M00532	R01514,R05790	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3
k59_1370301_3	283699.D172_3909	7.61e-22	93.2	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,2Q11F@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_1257909_1	76114.ebA3803	3.72e-115	343.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,2KVPK@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidases, C-terminal domain	dldH	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_1767257_1	572480.Arnit_0829	1.04e-39	135.0	COG0705@1|root,COG0705@2|Bacteria,1NH9I@1224|Proteobacteria,42RJD@68525|delta/epsilon subdivisions,2YPF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01694	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_1197391_1	1123518.ARWI01000001_gene2460	1.84e-97	291.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,46130@72273|Thiotrichales	72273|Thiotrichales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
k59_353918_1	1408813.AYMG01000038_gene270	5.13e-158	474.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	2.1.1.72	ko:K03427,ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,HSDR_N_2,Methylase_S,N6_Mtase,TaqI_C
k59_411177_1	1172190.M947_01630	4.03e-59	191.0	COG1376@1|root,COG1376@2|Bacteria,1RAMJ@1224|Proteobacteria,42Y3G@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_411177_2	563040.Saut_0848	3.32e-65	201.0	COG2346@1|root,COG2346@2|Bacteria,1Q5UZ@1224|Proteobacteria,42U39@68525|delta/epsilon subdivisions,2YRXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_14860_1	326298.Suden_1945	1.12e-75	238.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42QH4@68525|delta/epsilon subdivisions,2YNGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_1598015_1	1123518.ARWI01000001_gene783	6.51e-176	516.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,45ZRC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_639080_1	317025.Tcr_0384	8.63e-56	192.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,45ZVK@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_808606_1	484018.BACPLE_01368	9.28e-78	259.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,2FP6T@200643|Bacteroidia,4AKST@815|Bacteroidaceae	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_808606_2	1122179.KB890469_gene602	4.35e-70	237.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IQA2@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_129989_1	572480.Arnit_0126	4.41e-127	383.0	COG2984@1|root,COG4191@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CBQ@68525|delta/epsilon subdivisions,2YP5B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COGs COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,PAS_4
k59_1655826_1	504487.JCM19302_2221	4.48e-193	541.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1HYKT@117743|Flavobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_1655826_2	1178825.ALIH01000010_gene427	3.14e-64	207.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1HXB7@117743|Flavobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_74448_1	1353528.DT23_17160	5.89e-92	299.0	COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,He_PIG
k59_187519_1	317025.Tcr_1021	6.71e-141	404.0	COG2199@1|root,COG2199@2|Bacteria,1R4XN@1224|Proteobacteria,1RQ6S@1236|Gammaproteobacteria,461US@72273|Thiotrichales	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
k59_355610_1	1197477.IA57_09330	9.23e-106	319.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_751198_1	1121931.AUHG01000019_gene2979	6.95e-99	314.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1372039_1	1122225.AULQ01000006_gene968	1.4e-140	410.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1HY1T@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1541605_1	1484460.JSWG01000003_gene748	1.48e-147	429.0	COG2374@1|root,COG2374@2|Bacteria,4NHFV@976|Bacteroidetes	976|Bacteroidetes	O	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
k59_1541605_2	1380600.AUYN01000009_gene2033	5.65e-210	588.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1HXF8@117743|Flavobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1541605_3	1137281.D778_01334	6.72e-40	145.0	COG0545@1|root,COG0545@2|Bacteria,4NNK2@976|Bacteroidetes,1I2FD@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1259666_1	1122134.KB893650_gene561	7.86e-35	130.0	2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria,1XMC6@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
k59_1259666_2	1123518.ARWI01000001_gene682	1.32e-165	468.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,4606B@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_1712363_1	945713.IALB_1663	7.35e-126	379.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_696333_1	387093.SUN_0554	6.84e-54	186.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1259683_1	1121912.AUHD01000001_gene2453	1.65e-58	193.0	2E209@1|root,32X8E@2|Bacteria,4NSHA@976|Bacteroidetes,1I4IB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1599813_1	90814.KL370891_gene448	4.7e-07	52.0	2DBHN@1|root,2Z9BF@2|Bacteria,1QWQ3@1224|Proteobacteria,1S0YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1599813_2	1168065.DOK_12852	5.08e-49	174.0	2DBHN@1|root,2Z9BF@2|Bacteria,1QWQ3@1224|Proteobacteria,1S0YN@1236|Gammaproteobacteria,1J64E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1599813_4	317025.Tcr_0832	8.1e-60	196.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,461AN@72273|Thiotrichales	72273|Thiotrichales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1372070_1	945713.IALB_2133	2.23e-66	212.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ycjS	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_1372070_2	945713.IALB_2134	4.12e-17	80.5	COG1154@1|root,COG1154@2|Bacteria	2|Bacteria	H	1-deoxy-D-xylulose-5-phosphate synthase activity	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_864583_1	1121918.ARWE01000001_gene1409	4.57e-31	123.0	COG5002@1|root,COG5002@2|Bacteria,1R04G@1224|Proteobacteria,42ZVP@68525|delta/epsilon subdivisions,2X8ME@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
k59_525663_1	563040.Saut_1787	4.29e-193	545.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1769094_1	396588.Tgr7_2258	2.93e-21	89.4	2E23K@1|root,32XAV@2|Bacteria,1N7MZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1769094_2	1380387.JADM01000002_gene2279	9.11e-28	105.0	COG2197@1|root,COG2197@2|Bacteria,1RAAY@1224|Proteobacteria,1SJKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_9
k59_74521_1	1380600.AUYN01000007_gene3423	0.0	1115.0	COG0697@1|root,COG0697@2|Bacteria,4PKRH@976|Bacteroidetes,1HX4A@117743|Flavobacteriia	976|Bacteroidetes	EG	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_16537_1	323850.Shew_1836	7.07e-53	177.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria,2QAIM@267890|Shewanellaceae	1236|Gammaproteobacteria	F	PFAM Xanthine uracil vitamin C permease	uraA	GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082	-	ko:K02824,ko:K09016	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2,2.A.40.1.3	-	iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189,iSFxv_1172.SFxv_2795,iS_1188.S2690	Xan_ur_permease
k59_864594_1	1250005.PHEL85_2119	1.17e-107	321.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,1HZ6T@117743|Flavobacteriia,3VW8G@52959|Polaribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
k59_864594_2	504487.JCM19302_614	1.08e-23	94.7	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,1HYMQ@117743|Flavobacteriia	976|Bacteroidetes	G	Aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k59_1599841_1	90813.JQMT01000001_gene140	1e-116	353.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,4603K@72273|Thiotrichales	72273|Thiotrichales	O	magnesium chelatase	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_974745_1	326298.Suden_0397	1.48e-47	159.0	COG1076@1|root,COG1076@2|Bacteria,1N8QM@1224|Proteobacteria,43B25@68525|delta/epsilon subdivisions,2YT59@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_355689_1	62928.azo3455	9.47e-66	204.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,2KX20@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
k59_412979_1	945713.IALB_0752	3.25e-116	364.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_864635_1	411154.GFO_0393	2.89e-96	313.0	COG1345@1|root,COG3209@1|root,COG3391@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
k59_1712438_1	411154.GFO_1622	1.92e-108	319.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,1HYVJ@117743|Flavobacteriia	976|Bacteroidetes	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
k59_130102_2	1121403.AUCV01000016_gene4398	2.63e-53	185.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,42SXG@68525|delta/epsilon subdivisions,2WP6Y@28221|Deltaproteobacteria,2MNMK@213118|Desulfobacterales	28221|Deltaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C,PAP2,SNARE_assoc
k59_751292_1	504487.JCM19302_2126	6.02e-92	290.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
k59_1317633_1	1469557.JSWF01000014_gene2650	4.45e-201	567.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1HZFG@117743|Flavobacteriia	976|Bacteroidetes	M	Transporter	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
k59_300108_1	1347086.CCBA010000005_gene4011	0.000234	42.7	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus	91061|Bacilli	G	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific	nagE	-	2.7.1.193,2.7.1.199	ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00267,M00809	R02738,R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k59_300108_2	1027273.GZ77_23580	2.19e-10	61.6	COG1940@1|root,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,1RNEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon	nagC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	2.7.1.2	ko:K00845,ko:K02565	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	MarR,ROK
k59_130105_1	411154.GFO_2405	2.03e-92	273.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,1I1JP@117743|Flavobacteriia	976|Bacteroidetes	Q	SAM-dependent	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
k59_1769147_1	1123518.ARWI01000001_gene665	4.37e-182	521.0	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria,460A7@72273|Thiotrichales	72273|Thiotrichales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1769147_2	1123518.ARWI01000001_gene664	0.0	933.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,45ZQ7@72273|Thiotrichales	72273|Thiotrichales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_244094_1	62928.azo1705	2.7e-18	77.8	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,2KX2V@206389|Rhodocyclales	206389|Rhodocyclales	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k59_244094_2	1198452.Jab_2c06110	7.48e-05	45.8	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,473C5@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	PPIC-type PPIASE domain	cbf2	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
k59_696418_1	1121930.AQXG01000010_gene3043	1.91e-42	152.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_582448_1	1121931.AUHG01000011_gene2360	7.25e-207	582.0	2DBB7@1|root,2Z85R@2|Bacteria,4NM36@976|Bacteroidetes,1I0WW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_300129_1	688270.Celal_2980	8.01e-83	253.0	COG0664@1|root,COG0664@2|Bacteria,4NP9Z@976|Bacteroidetes,1I2N5@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1317656_1	1121931.AUHG01000017_gene1495	1.76e-30	107.0	2E3TF@1|root,32YQY@2|Bacteria,4NUMK@976|Bacteroidetes,1I52K@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1317656_2	1123234.AUKI01000011_gene1236	3.62e-23	100.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_808795_1	323850.Shew_2218	1.69e-78	258.0	COG4251@1|root,COG4251@2|Bacteria,1REKX@1224|Proteobacteria,1T2NR@1236|Gammaproteobacteria,2QA9K@267890|Shewanellaceae	1236|Gammaproteobacteria	T	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,dCache_1
k59_1712488_1	1380600.AUYN01000009_gene1823	1.23e-50	166.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_1712488_2	1121912.AUHD01000005_gene1815	1.58e-301	830.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1486451_1	563040.Saut_1100	9.57e-49	160.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2YT63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_1486451_3	326298.Suden_1124	4.19e-97	285.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2YPJE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_1486451_4	929558.SMGD1_2638	2.68e-11	65.1	COG1261@1|root,COG1261@2|Bacteria,1Q3ZV@1224|Proteobacteria,42Y1K@68525|delta/epsilon subdivisions,2YQRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chaperone for flagella basal body P-ring formation	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_1712500_1	929558.SMGD1_0762	1.46e-18	84.7	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1712500_2	563040.Saut_1751	1.32e-90	271.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1105526_1	1205683.CAKR01000009_gene2044	5.04e-115	359.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,41FCG@629|Yersinia	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	lacZ	GO:0000287,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0031420,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0046872,GO:0071704,GO:1901575,GO:1902494	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	iAF1260.b0344,iB21_1397.B21_00302,iECBD_1354.ECBD_3313,iECB_1328.ECB_00298,iECDH1ME8569_1439.ECDH1ME8569_0331,iECD_1391.ECD_00298,iECNA114_1301.ECNA114_0327,iEcDH1_1363.EcDH1_3262,iJO1366.b0344,iJR904.b0344,iY75_1357.Y75_RS01775	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_203466_1	1123518.ARWI01000001_gene415	2.09e-73	236.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,46098@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_203466_2	1123514.KB905899_gene1339	5.56e-42	145.0	COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,461GR@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k59_1444530_1	1453500.AT05_00865	1.01e-64	206.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia	976|Bacteroidetes	S	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_1275711_1	1077972.ARGLB_083_00400	4.11e-17	86.3	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,1W82R@1268|Micrococcaceae	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812,ko:K00841,ko:K10907	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00525	R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_766978_1	1208323.B30_17088	1.13e-20	90.9	COG0369@1|root,COG3182@1|root,COG0369@2|Bacteria,COG3182@2|Bacteria,1MWYV@1224|Proteobacteria,2TRCH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM oxidoreductase FAD NAD(P)-binding domain protein	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,FAD_binding_6,FeS,Flavodoxin_1,NAD_binding_1,PepSY_TM
k59_766978_2	1288298.rosmuc_02593	3.08e-80	240.0	29N8T@1|root,3096N@2|Bacteria,1RJCI@1224|Proteobacteria,2U5NK@28211|Alphaproteobacteria,46NHS@74030|Roseovarius	28211|Alphaproteobacteria	S	Predicted periplasmic protein (DUF2271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2271
k59_1671966_1	243231.GSU0103	1.08e-56	197.0	COG2199@1|root,COG2206@1|root,COG4251@1|root,COG2206@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
k59_429033_1	411154.GFO_1976	2.05e-08	54.3	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1HWJG@117743|Flavobacteriia	976|Bacteroidetes	S	protein with a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_429033_2	411154.GFO_1977	2.25e-94	282.0	COG0671@1|root,COG0671@2|Bacteria,4NR78@976|Bacteroidetes,1HXB4@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_1105569_1	411154.GFO_3553	4.92e-166	486.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit	mrpA	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
k59_1105569_2	1121931.AUHG01000010_gene583	1.55e-49	159.0	COG2111@1|root,COG2111@2|Bacteria,4NNPP@976|Bacteroidetes,1I231@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter, MnhB	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
k59_597564_1	926559.JoomaDRAFT_1268	1.96e-33	126.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_597564_2	880071.Fleli_1129	6.31e-06	49.3	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,47JPB@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
k59_1616768_1	929558.SMGD1_0709	5.52e-117	352.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1446378_1	317025.Tcr_0832	4.97e-106	315.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,461AN@72273|Thiotrichales	72273|Thiotrichales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_543142_1	4555.Si000288m	9.96e-05	43.9	COG0481@1|root,KOG0462@2759|Eukaryota,37HN6@33090|Viridiplantae,3GBWC@35493|Streptophyta,3KN4W@4447|Liliopsida,3I2HJ@38820|Poales	35493|Streptophyta	J	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_543142_2	1178825.ALIH01000017_gene648	5.51e-175	490.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1HXM5@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_657200_1	349521.HCH_06190	2.45e-41	149.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1XHXW@135619|Oceanospirillales	135619|Oceanospirillales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_373300_1	391603.FBALC1_08013	4.37e-33	124.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1HXB0@117743|Flavobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
k59_373300_2	1178825.ALIH01000018_gene1169	6.46e-16	76.6	2DH3V@1|root,2ZYAH@2|Bacteria,4NNGU@976|Bacteroidetes,1I35W@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1787304_1	929558.SMGD1_1612	3.45e-54	176.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_1787304_2	929558.SMGD1_1611	1.62e-34	124.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1559259_1	626418.bglu_1g28240	1.39e-75	229.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,1K4HB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
k59_715999_1	563040.Saut_1352	2.34e-104	311.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2YMGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1559268_1	264462.Bd1535	0.000607	43.5	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,RsbRD_N,SBP_bac_3
k59_1559268_2	1165841.SULAR_09209	3.93e-84	256.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2YNCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0330	IlvC,IlvN
k59_1618695_1	572480.Arnit_3038	1.97e-265	758.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1446412_1	945713.IALB_2620	1.94e-49	177.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_92421_1	225849.swp_1455	1.09e-105	318.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,2Q93S@267890|Shewanellaceae	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_937162_1	1121931.AUHG01000019_gene3044	3.71e-87	276.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_1107499_1	1123326.JFBL01000001_gene1279	7.88e-24	92.0	COG5554@1|root,COG5554@2|Bacteria,1Q3JU@1224|Proteobacteria,42XF5@68525|delta/epsilon subdivisions,2YQVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	nitrogen fixation protein FixT	-	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
k59_1107499_2	944547.ABLL_0014	3.41e-34	133.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1164441_1	411154.GFO_0587	1.79e-101	298.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_205392_1	572480.Arnit_2225	1.26e-114	343.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_147692_1	425104.Ssed_3031	4.15e-122	357.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,2QAFA@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k59_768922_1	1380600.AUYN01000001_gene2670	2.24e-180	553.0	COG1345@1|root,COG1361@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
k59_827775_1	317025.Tcr_1521	3.54e-101	319.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,45ZRH@72273|Thiotrichales	72273|Thiotrichales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_827775_2	1123517.JOMR01000001_gene1489	2.15e-111	321.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,460P5@72273|Thiotrichales	72273|Thiotrichales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_827775_3	90814.KL370891_gene641	3.38e-31	117.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,461SY@72273|Thiotrichales	72273|Thiotrichales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_1336426_1	981327.F925_02112	1.11e-65	202.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,3NMJN@468|Moraxellaceae	1236|Gammaproteobacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008824,GO:0009056,GO:0009439,GO:0009440,GO:0009987,GO:0016829,GO:0016840,GO:0034641,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:1901564,GO:1901565,GO:1901575	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
k59_990676_1	1121931.AUHG01000010_gene802	3.41e-240	681.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_827786_2	1380600.AUYN01000001_gene2537	3.04e-47	154.0	COG3296@1|root,COG3296@2|Bacteria,4NQGV@976|Bacteroidetes,1I2WN@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870,SHOCT
k59_1210848_1	411154.GFO_3267	4.87e-29	108.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1210848_2	1121931.AUHG01000010_gene251	3.1e-47	156.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1505061_1	572480.Arnit_0158	1.71e-89	283.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMM8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_318370_1	1232410.KI421426_gene1342	5.15e-42	150.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43S03@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribonuclease E/G family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1730294_1	1123514.KB905899_gene1322	8.74e-23	96.3	COG2142@1|root,COG2142@2|Bacteria,1P4UA@1224|Proteobacteria,1RW46@1236|Gammaproteobacteria,463E4@72273|Thiotrichales	72273|Thiotrichales	C	Succinate dehydrogenase hydrophobic membrane anchor	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
k59_1446536_1	572480.Arnit_0436	6.83e-118	344.0	COG0679@1|root,COG0679@2|Bacteria,1RDRQ@1224|Proteobacteria	1224|Proteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans,SBF
k59_318376_1	929558.SMGD1_2313	1.01e-131	392.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_599135_1	1187851.A33M_0279	1.01e-64	209.0	COG4177@1|root,COG4177@2|Bacteria,1NE3E@1224|Proteobacteria,2TTWY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_937273_1	1123518.ARWI01000001_gene466	1.21e-151	432.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,1RMZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k59_1164577_1	313590.MED134_01785	2.22e-33	126.0	COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,1HY2N@117743|Flavobacteriia,37DWU@326319|Dokdonia	976|Bacteroidetes	E	Aminotransferase class-V	phnW	-	2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K03430	ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R04152	RC00006,RC00008,RC00018,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_543286_1	1523503.JPMY01000010_gene2465	4.11e-77	239.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	amino acid ABC transporter	yhdY	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02029,ko:K09971,ko:K10002,ko:K10037	ko02010,ko02020,map02010,map02020	M00227,M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.2,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_543286_2	95619.PM1_0215745	1.5e-08	54.7	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	amino acid ABC transporter	aapQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_716176_1	1484460.JSWG01000009_gene439	1.4e-73	223.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1HYHU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_318404_1	1123517.JOMR01000001_gene1040	1.52e-70	231.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,1RS9G@1236|Gammaproteobacteria,461UT@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_937281_1	1565129.JSFF01000022_gene1416	1.83e-145	419.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,2Q8XZ@267890|Shewanellaceae	1236|Gammaproteobacteria	EGP	PFAM nucleoside H symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k59_1730342_1	318167.Sfri_0560	1.88e-21	90.1	COG2197@1|root,COG2197@2|Bacteria,1N5RH@1224|Proteobacteria,1SBHK@1236|Gammaproteobacteria,2QA3D@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_827906_1	1280001.BAOA01000028_gene4961	6.59e-40	144.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XSPG@135623|Vibrionales	135623|Vibrionales	C	COG1960 Acyl-CoA dehydrogenases	liuA	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_657416_1	316067.Geob_1105	1.79e-38	137.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_1210942_1	944546.ABED_1639	1.02e-36	138.0	28NZU@1|root,2ZBWK@2|Bacteria,1RCU0@1224|Proteobacteria,42ZJG@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_769061_1	309807.SRU_0558	4.8e-59	201.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1FITH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_543317_1	323850.Shew_0282	3.09e-94	281.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,2Q8NJ@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	yihG	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_1787517_1	675806.VII_000889	9.9e-12	63.9	COG0782@1|root,COG0782@2|Bacteria,1MZNY@1224|Proteobacteria,1S8V4@1236|Gammaproteobacteria,1XX79@135623|Vibrionales	135623|Vibrionales	K	Rnk N-terminus	-	-	-	ko:K06140	-	-	-	-	ko00000,ko03000	-	-	-	GreA_GreB,Rnk_N
k59_1107684_1	319224.Sputcn32_0454	2.24e-33	120.0	2A9E2@1|root,30YJE@2|Bacteria,1QFYJ@1224|Proteobacteria,1TDA2@1236|Gammaproteobacteria,2QE60@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_599180_1	1123518.ARWI01000001_gene1342	2.34e-22	97.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461Z4@72273|Thiotrichales	72273|Thiotrichales	NT	helical bimodular (HBM) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
k59_599180_2	317025.Tcr_1586	1.02e-94	283.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	COG1291 Flagellar motor component	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_1390148_2	1415778.JQMM01000001_gene1078	3.36e-05	48.5	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1SZUE@1236|Gammaproteobacteria,1J6NY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_373544_1	1121912.AUHD01000020_gene3390	4.47e-73	228.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia	976|Bacteroidetes	S	NADP oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
k59_1787536_1	1137281.D778_01537	2.57e-79	258.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
k59_1787536_2	1286632.P278_25240	5.84e-98	293.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_33875_1	1168067.JAGP01000001_gene584	3.76e-164	495.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,461VE@72273|Thiotrichales	72273|Thiotrichales	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_205600_1	1123518.ARWI01000001_gene450	5.32e-99	306.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,45ZPN@72273|Thiotrichales	72273|Thiotrichales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1618939_1	497321.C664_14614	3.2e-105	326.0	COG4389@1|root,COG4389@2|Bacteria,1MWEH@1224|Proteobacteria,2VIZV@28216|Betaproteobacteria,2KUTK@206389|Rhodocyclales	206389|Rhodocyclales	L	Site-specific recombinase	-	-	-	-	-	-	-	-	-	-	-	-	SpecificRecomb
k59_147895_1	563040.Saut_1459	2.21e-164	479.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_827971_1	1380600.AUYN01000009_gene1324	1.45e-95	314.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2
k59_827987_1	326298.Suden_1155	2.81e-118	344.0	COG1227@1|root,COG1227@2|Bacteria,1P9JN@1224|Proteobacteria,42N0W@68525|delta/epsilon subdivisions,2YNNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
k59_716291_1	1123228.AUIH01000005_gene654	3.04e-88	271.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_543388_1	411154.GFO_1545	4.53e-247	685.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1HXRM@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_1730462_1	85643.Tmz1t_3629	1.38e-33	120.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,2KVUE@206389|Rhodocyclales	206389|Rhodocyclales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_901706_1	1123514.KB905899_gene1702	2.04e-91	284.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,45ZT8@72273|Thiotrichales	72273|Thiotrichales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_1230405_1	1120968.AUBX01000002_gene1450	1.8e-78	236.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	4.2.99.20	ko:K06889,ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_5
k59_1230405_2	616991.JPOO01000003_gene1397	4.04e-97	286.0	COG4430@1|root,COG4430@2|Bacteria,4NG4C@976|Bacteroidetes,1HXYY@117743|Flavobacteriia,23H5C@178469|Arenibacter	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
k59_1070227_1	563040.Saut_0403	3.09e-96	286.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2YMKE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar biosynthetic protein fliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_338702_1	1121931.AUHG01000012_gene2873	5.26e-101	305.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1HY94@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_901735_1	1353537.TP2_17920	5.78e-69	229.0	COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U36H@28211|Alphaproteobacteria,2XNWW@285107|Thioclava	28211|Alphaproteobacteria	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_1230421_1	1121931.AUHG01000010_gene600	3.39e-93	286.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_677772_1	1123514.KB905900_gene2258	5.18e-74	229.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,461HI@72273|Thiotrichales	72273|Thiotrichales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_677772_2	1123518.ARWI01000001_gene1487	2.9e-61	191.0	2BXG1@1|root,347YM@2|Bacteria,1P06C@1224|Proteobacteria,1SRS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_677772_3	1123518.ARWI01000001_gene702	2.65e-06	47.8	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	mauD	-	-	ko:K12057	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AhpC-TSA,DUF4369,Thioredoxin,TraF
k59_1184726_1	1392490.JHZX01000001_gene864	2.33e-53	177.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1HX10@117743|Flavobacteriia	976|Bacteroidetes	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_1184726_2	1380600.AUYN01000003_gene191	7.26e-139	423.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_789733_1	1123514.KB905902_gene294	9.75e-50	163.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,46182@72273|Thiotrichales	72273|Thiotrichales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_789733_2	1123514.KB905902_gene282	5.91e-174	491.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,460A9@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,TusA
k59_789733_3	1123514.KB905902_gene281	1.26e-10	60.8	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales	72273|Thiotrichales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_617741_1	1380600.AUYN01000007_gene3423	1.31e-139	427.0	COG0697@1|root,COG0697@2|Bacteria,4PKRH@976|Bacteroidetes,1HX4A@117743|Flavobacteriia	976|Bacteroidetes	EG	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_617741_2	1178825.ALIH01000003_gene2002	2.69e-81	247.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1298122_1	1172190.M947_06470	7.67e-71	230.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k59_844361_1	113395.AXAI01000009_gene2555	3.2e-17	84.7	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_52642_1	319224.Sputcn32_3669	6.91e-124	359.0	COG4606@1|root,COG4606@2|Bacteria,1MVSV@1224|Proteobacteria,1RQCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fatD	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_450430_1	223926.28807128	4.56e-108	333.0	2AQ5Y@1|root,31FBF@2|Bacteria,1RI89@1224|Proteobacteria,1TF70@1236|Gammaproteobacteria,1Y0Q8@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_789774_1	1178825.ALIH01000004_gene2897	6.4e-118	347.0	COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,1IIKI@117743|Flavobacteriia	976|Bacteroidetes	M	Sucrose synthase	gmhA	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
k59_393681_1	563040.Saut_1063	1.35e-159	473.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1578680_1	1178825.ALIH01000013_gene535	3.92e-99	292.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1578680_2	1380600.AUYN01000007_gene3302	4.59e-29	104.0	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,1I54J@117743|Flavobacteriia	976|Bacteroidetes	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_953955_1	1122194.AUHU01000010_gene3140	1.39e-206	593.0	COG1874@1|root,COG1874@2|Bacteria,1NDQP@1224|Proteobacteria,1SDV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-galactosidase	bga2	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,Glyco_hydro_35
k59_1128107_1	1137281.D778_01019	5.61e-128	372.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HYN5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_338816_1	1123518.ARWI01000001_gene1920	7.98e-43	144.0	COG3012@1|root,COG3012@2|Bacteria,1N4HZ@1224|Proteobacteria,1SFB1@1236|Gammaproteobacteria,462H1@72273|Thiotrichales	72273|Thiotrichales	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_338816_2	1123514.KB905901_gene85	4.53e-26	106.0	COG3203@1|root,COG3203@2|Bacteria,1RH1J@1224|Proteobacteria,1S06S@1236|Gammaproteobacteria,4632G@72273|Thiotrichales	72273|Thiotrichales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_1578728_1	411154.GFO_3565	2.82e-149	428.0	COG0304@1|root,COG0304@2|Bacteria,4NGJD@976|Bacteroidetes,1HYKN@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1070367_1	572480.Arnit_2727	4.07e-152	431.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,42NZ1@68525|delta/epsilon subdivisions,2YN5D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
k59_1230542_1	876269.ARWA01000001_gene2103	5.45e-34	117.0	COG1146@1|root,COG1146@2|Bacteria,1N06F@1224|Proteobacteria,2UBYF@28211|Alphaproteobacteria,3NCP6@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	MA20_14855	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_1632253_1	367737.Abu_0675	1.75e-51	180.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,42PP5@68525|delta/epsilon subdivisions,2YN5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter ATP-binding	pglK	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008643,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015772,GO:0015920,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0034645,GO:0036211,GO:0042623,GO:0042626,GO:0043170,GO:0043412,GO:0043413,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0051179,GO:0051234,GO:0055085,GO:0070085,GO:0071702,GO:0071704,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1128167_1	1123518.ARWI01000001_gene708	3.49e-86	263.0	COG3439@1|root,COG3439@2|Bacteria,1RBWN@1224|Proteobacteria,1S74G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1070385_1	1123518.ARWI01000001_gene1784	9.8e-135	392.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,46070@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_789872_1	1048983.EL17_00395	6.67e-11	69.7	COG0642@1|root,COG2205@2|Bacteria,4PKI2@976|Bacteroidetes	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9
k59_225463_3	411154.GFO_3340	2.7e-88	261.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_393785_1	1123228.AUIH01000094_gene1675	1.33e-49	167.0	2E4GK@1|root,32ZBS@2|Bacteria,1N72D@1224|Proteobacteria,1SD9M@1236|Gammaproteobacteria,1XNDI@135619|Oceanospirillales	135619|Oceanospirillales	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
k59_507834_1	1168067.JAGP01000001_gene1929	1.94e-95	290.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,4612S@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_507834_2	1123518.ARWI01000001_gene1393	9.93e-65	207.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,462E0@72273|Thiotrichales	72273|Thiotrichales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
k59_450546_1	411154.GFO_2406	3.32e-68	209.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_450546_2	411154.GFO_2407	3.96e-16	74.3	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1I2WH@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_1184887_1	62928.azo0303	7.62e-153	439.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,2KVJW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_507842_1	768671.ThimaDRAFT_1928	3.61e-91	280.0	2C69V@1|root,33SX3@2|Bacteria,1NTPV@1224|Proteobacteria,1SMZB@1236|Gammaproteobacteria,1X0D2@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1298273_1	1121931.AUHG01000011_gene2320	2.54e-65	199.0	2DM5N@1|root,31TGW@2|Bacteria,4PKNS@976|Bacteroidetes,1I4D7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1298273_2	1121931.AUHG01000011_gene2319	2.44e-108	312.0	COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,1I1BH@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k59_338889_1	1249975.JQLP01000005_gene1713	2.08e-93	283.0	COG2321@1|root,COG2321@2|Bacteria,4NKTG@976|Bacteroidetes,1I06E@117743|Flavobacteriia	976|Bacteroidetes	S	neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_954041_1	1121931.AUHG01000012_gene2877	2.74e-154	462.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_954041_2	1121931.AUHG01000012_gene2876	2.63e-36	135.0	COG3637@1|root,COG3637@2|Bacteria,4PMC3@976|Bacteroidetes,1IJRA@117743|Flavobacteriia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1466127_1	1249997.JHZW01000003_gene2862	4.21e-118	342.0	COG0791@1|root,COG0791@2|Bacteria,4NSRM@976|Bacteroidetes,1I9IJ@117743|Flavobacteriia	976|Bacteroidetes	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1466132_1	945713.IALB_2613	7.98e-76	231.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	MA20_27875	-	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_844528_1	1123518.ARWI01000001_gene471	4.41e-129	383.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,1RQ5C@1236|Gammaproteobacteria,4622S@72273|Thiotrichales	72273|Thiotrichales	F	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k59_844528_2	1123518.ARWI01000001_gene472	4.86e-52	183.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,461YR@72273|Thiotrichales	72273|Thiotrichales	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_225518_1	1121931.AUHG01000013_gene2460	5.46e-76	247.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1HWNZ@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_562174_1	5022.CBX96380	1.57e-10	61.6	COG0229@1|root,KOG0856@2759|Eukaryota,3A0BN@33154|Opisthokonta,3P2R6@4751|Fungi,3QUJD@4890|Ascomycota,201MN@147541|Dothideomycetes,4KBJY@92860|Pleosporales	4751|Fungi	O	SelR domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033554,GO:0033743,GO:0034599,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:1901564,GO:1990748	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_562174_2	1121931.AUHG01000020_gene3142	4.85e-96	281.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I1Y2@117743|Flavobacteriia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_1407988_1	1313421.JHBV01000003_gene588	5.29e-70	227.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
k59_507891_1	90814.KL370891_gene562	0.000995	42.7	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,45ZQ0@72273|Thiotrichales	72273|Thiotrichales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_507891_2	317025.Tcr_1654	1.08e-66	225.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,45ZMV@72273|Thiotrichales	72273|Thiotrichales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2,OstA_C
k59_52801_2	1515746.HR45_03780	3.61e-30	113.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,2QAVV@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.47	ko:K00034,ko:K00059	ko00030,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00572	R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_225535_1	1121931.AUHG01000020_gene3139	1.53e-130	381.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia	976|Bacteroidetes	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_1184951_1	1565129.JSFF01000002_gene3507	5.35e-108	329.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RN7S@1236|Gammaproteobacteria,2Q94C@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase U32	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k59_1070485_1	425104.Ssed_1532	1.52e-95	299.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,2Q8KV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_52808_1	1121931.AUHG01000010_gene422	5.28e-57	179.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1I450@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_52808_2	411154.GFO_3442	4.72e-34	124.0	28JBH@1|root,2Z967@2|Bacteria,4NNHF@976|Bacteroidetes,1HYEA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
k59_617976_1	1250005.PHEL85_3150	2.5e-08	55.1	COG1621@1|root,COG4099@1|root,COG1621@2|Bacteria,COG4099@2|Bacteria,4PI4D@976|Bacteroidetes,1IES8@117743|Flavobacteriia,3VXDU@52959|Polaribacter	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_617976_4	1122176.KB903548_gene1207	1.08e-159	458.0	COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,1IP1W@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_393923_1	1278309.KB907101_gene657	9.26e-19	82.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1XJ6X@135619|Oceanospirillales	135619|Oceanospirillales	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_393923_2	1278309.KB907101_gene656	9e-83	255.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XHFB@135619|Oceanospirillales	135619|Oceanospirillales	M	Lipoprotein releasing system, transmembrane protein	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1298370_1	1122176.KB903542_gene353	2.56e-43	160.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes	976|Bacteroidetes	M	sodium ion export across plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
k59_167326_2	991.IW20_02435	1.41e-20	90.9	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia,2NUBG@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1298385_1	497321.C664_12715	6.21e-234	651.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,2KUNP@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_902103_1	713586.KB900536_gene2240	6.33e-22	100.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1578963_1	1178825.ALIH01000006_gene1550	1.36e-161	464.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_1694438_1	1121912.AUHD01000001_gene2379	5.25e-291	808.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_790112_1	317025.Tcr_1347	3.72e-192	541.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RR0P@1236|Gammaproteobacteria,460R9@72273|Thiotrichales	72273|Thiotrichales	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k59_1298468_1	1121931.AUHG01000011_gene1742	3.12e-71	214.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1I2XZ@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
k59_1298468_2	411154.GFO_2782	1.04e-38	137.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1HYAM@117743|Flavobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
k59_620898_1	1380600.AUYN01000012_gene2999	1.61e-248	690.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_620898_2	688270.Celal_3633	2.87e-114	335.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1HWKD@117743|Flavobacteriia,1F9S9@104264|Cellulophaga	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
k59_1233561_1	313603.FB2170_01482	9.67e-78	238.0	COG0657@1|root,COG0657@2|Bacteria,4NJ8D@976|Bacteroidetes,1HZX0@117743|Flavobacteriia,2PHAN@252356|Maribacter	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH,Lipase_GDSL_2,Peptidase_S9
k59_1634307_1	1137281.D778_00836	5.79e-169	497.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_1072565_1	1121931.AUHG01000012_gene2881	1.37e-120	353.0	COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,1IJAV@117743|Flavobacteriia	976|Bacteroidetes	EGP	Nucleoside H symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
k59_621001_1	998674.ATTE01000001_gene1385	9.49e-116	336.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,460F0@72273|Thiotrichales	72273|Thiotrichales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_621001_2	1358423.N180_12375	5.73e-73	227.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1IRWF@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k59_621001_3	717773.Thicy_1181	4.05e-09	56.2	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,45ZU1@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1014432_1	1049564.TevJSym_aa01980	2.28e-42	145.0	COG3439@1|root,COG3439@2|Bacteria,1REDZ@1224|Proteobacteria,1RPW4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_452244_2	1123514.KB905901_gene139	5.08e-79	237.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,460Q7@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_339198_1	411154.GFO_1965	3.28e-100	309.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,1HXGN@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_960614_1	1122207.MUS1_11405	5.49e-19	85.9	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,1T23I@1236|Gammaproteobacteria,1XQZC@135619|Oceanospirillales	135619|Oceanospirillales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
k59_960614_2	1129794.C427_1414	7.19e-23	92.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,467AX@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_678242_1	1565129.JSFF01000002_gene3605	4.1e-44	145.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,2QBKP@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM DNA polymerase III chi subunit, HolC	holC	GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
k59_678242_2	1565129.JSFF01000002_gene3604	1.21e-85	275.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,2Q9PC@267890|Shewanellaceae	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1299597_1	326298.Suden_2098	2.15e-80	252.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_904206_1	1168067.JAGP01000001_gene986	4.24e-173	506.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,45ZS8@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the aconitase IPM isomerase family	-	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_452274_1	709032.Sulku_1510	4.32e-132	386.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2YNUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase cofactor biosynthesis protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_847542_2	926559.JoomaDRAFT_2999	7.08e-147	416.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,1HYB4@117743|Flavobacteriia	976|Bacteroidetes	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_847542_3	946077.W5A_13091	1.34e-46	156.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_1525503_1	90814.KL370891_gene1712	3.74e-20	99.4	COG3307@1|root,COG3307@2|Bacteria,1N5VZ@1224|Proteobacteria,1RMC4@1236|Gammaproteobacteria,46329@72273|Thiotrichales	72273|Thiotrichales	M	O-Antigen ligase	-	-	-	ko:K13009	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Wzy_C,Wzy_C_2
k59_1751475_1	313603.FB2170_06640	7.21e-57	187.0	COG1940@1|root,COG1940@2|Bacteria,4NM8T@976|Bacteroidetes,1I06R@117743|Flavobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_1751475_2	1250232.JQNJ01000001_gene1563	3.38e-114	344.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HZ5E@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_904210_1	323850.Shew_2753	1.76e-74	246.0	COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,2QACV@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
k59_113418_1	349521.HCH_03259	2.37e-91	279.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1XNMD@135619|Oceanospirillales	1236|Gammaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_33
k59_479_1	1237149.C900_05609	6.65e-62	210.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_480_1	1121931.AUHG01000011_gene1644	2.39e-147	429.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_56959_1	318167.Sfri_2089	3.96e-82	252.0	28MTH@1|root,2ZB1P@2|Bacteria,1R6K1@1224|Proteobacteria,1S3MH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4007)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4007
k59_1299619_1	411154.GFO_2065	2.7e-112	348.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1638555_1	1123514.KB905901_gene123	6.42e-28	107.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	dsbH	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	Thioredoxin_2,Thioredoxin_7
k59_1638555_2	1123518.ARWI01000001_gene1415	1.59e-145	419.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,4611C@72273|Thiotrichales	72273|Thiotrichales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_791237_1	411154.GFO_3090	1.71e-121	362.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_621801_1	56780.SYN_02063	3.55e-31	118.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,42Q98@68525|delta/epsilon subdivisions,2WM5S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
k59_621801_2	983920.Y88_2300	4.91e-92	281.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,2TU4P@28211|Alphaproteobacteria,2K1I9@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1017219_1	1121931.AUHG01000011_gene2388	1.07e-103	330.0	COG1352@1|root,COG2201@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HWYQ@117743|Flavobacteriia	976|Bacteroidetes	T	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
k59_1751514_1	1355368.JART01000015_gene1912	2.16e-11	63.9	COG1246@1|root,COG1305@1|root,COG1246@2|Bacteria,COG1305@2|Bacteria,1RJJ1@1224|Proteobacteria,43B4M@68525|delta/epsilon subdivisions,2YP25@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Transglut_core
k59_1751514_2	572480.Arnit_1576	7.89e-93	272.0	COG3708@1|root,COG3708@2|Bacteria,1NEQY@1224|Proteobacteria,42VI3@68525|delta/epsilon subdivisions,2YQ9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
k59_1751514_3	572480.Arnit_1578	1.59e-14	72.4	COG0697@1|root,COG0697@2|Bacteria,1Q0QR@1224|Proteobacteria,42N25@68525|delta/epsilon subdivisions,2YRH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Putative multidrug resistance efflux transporter	-	-	-	-	-	-	-	-	-	-	-	-	EmrE
k59_1638582_1	1121931.AUHG01000017_gene1593	5.14e-191	552.0	COG2207@1|root,COG3063@1|root,COG5616@1|root,COG2207@2|Bacteria,COG3063@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_2,TPR_8
k59_532_1	1355368.JART01000020_gene1195	2.37e-108	322.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,43B09@68525|delta/epsilon subdivisions,2YMJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_508731_1	926559.JoomaDRAFT_0885	9.56e-34	122.0	COG3637@1|root,COG3637@2|Bacteria,4NTE4@976|Bacteroidetes,1I30I@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
k59_791275_1	211586.SO_2728	1.43e-112	328.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,2QAQX@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_113483_1	1392490.JHZX01000001_gene3395	1.9e-167	493.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_847599_1	1392498.JQLH01000001_gene64	1.02e-74	239.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia,2PG3C@252356|Maribacter	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
k59_282836_1	1121012.AUKX01000005_gene3603	1.13e-28	112.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1HXW7@117743|Flavobacteriia,23GEP@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	nagA	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_282836_2	1550091.JROE01000005_gene2306	4.99e-260	766.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IV7I@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_791288_1	1380600.AUYN01000007_gene3314	1.01e-178	533.0	COG1345@1|root,COG3391@1|root,COG1345@2|Bacteria,COG3391@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LTD
k59_791288_2	1380600.AUYN01000007_gene3315	3.3e-83	248.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1I25J@117743|Flavobacteriia	976|Bacteroidetes	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k59_791288_3	1178825.ALIH01000013_gene547	4.22e-49	163.0	298AX@1|root,2ZVGF@2|Bacteria,4NNYM@976|Bacteroidetes,1I1ZZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_791288_4	1380600.AUYN01000007_gene3316	3.57e-103	304.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1HWP6@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_791296_1	411154.GFO_0772	3.38e-110	333.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
k59_1243108_1	1122179.KB890469_gene602	1.44e-119	374.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IQA2@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_960730_1	317025.Tcr_0930	4.53e-85	255.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,460CA@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_960730_2	90814.KL370891_gene1259	6.54e-80	239.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1SNKE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_960730_3	493475.GARC_0818	2.44e-46	166.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,1S87U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5,DUF915,LCAT,PGAP1
k59_1356065_2	504487.JCM19302_2875	5.38e-122	350.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia	976|Bacteroidetes	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
k59_1356065_3	1178825.ALIH01000015_gene1871	8.83e-64	201.0	COG3637@1|root,COG3637@2|Bacteria,4NNCG@976|Bacteroidetes,1I1EV@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
k59_1356065_4	504487.JCM19302_2873	1.04e-80	246.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1HX36@117743|Flavobacteriia	976|Bacteroidetes	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_226515_1	983548.Krodi_1133	3.05e-72	241.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_452405_1	1380600.AUYN01000001_gene2388	2.62e-70	221.0	COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1HXTB@117743|Flavobacteriia	976|Bacteroidetes	E	Allophanate hydrolase subunit 2	-	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
k59_452405_2	745718.JADT01000024_gene537	2.29e-108	316.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia	976|Bacteroidetes	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_1638666_2	1237149.C900_02701	1.24e-09	57.0	COG2860@1|root,COG2860@2|Bacteria,4NEXS@976|Bacteroidetes,47PWQ@768503|Cytophagia	976|Bacteroidetes	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_960763_1	76114.ebA6521	3.32e-75	235.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,2KWAS@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_960764_1	1121931.AUHG01000020_gene3163	1.84e-116	343.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1HZCP@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_1525636_1	1168034.FH5T_02105	8.9e-75	232.0	COG3507@1|root,COG3507@2|Bacteria,4NDUM@976|Bacteroidetes,2FM23@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_1525636_2	926559.JoomaDRAFT_2663	1.38e-07	53.1	COG3507@1|root,COG3507@2|Bacteria,4NFU3@976|Bacteroidetes,1HYQR@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
k59_452411_1	1232683.ADIMK_0732	4.03e-91	277.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,4654B@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potF	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
k59_452411_2	1122201.AUAZ01000009_gene2770	8.62e-155	445.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,46CJY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K11076	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	ABC_tran,TOBE_2
k59_1299753_1	398767.Glov_2665	8.51e-41	140.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42T96@68525|delta/epsilon subdivisions,2X5B8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
k59_1299753_2	945713.IALB_3198	9.66e-44	154.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_1638680_1	504487.JCM19302_717	4.81e-172	488.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,1HWQE@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_1638680_2	555500.I215_11369	9.14e-40	142.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_57107_1	425104.Ssed_4364	2.99e-16	72.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,1SCB0@1236|Gammaproteobacteria,2QCSC@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_57107_2	929556.Solca_1319	2.07e-56	186.0	COG1266@1|root,COG1266@2|Bacteria,4NPEG@976|Bacteroidetes,1IUFC@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_170083_1	643867.Ftrac_1690	2.47e-100	302.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_1186792_1	616991.JPOO01000001_gene2797	2.28e-44	157.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1HXWR@117743|Flavobacteriia,23H1V@178469|Arenibacter	976|Bacteroidetes	G	SAF	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k59_1186792_2	1392490.JHZX01000001_gene2019	1.56e-203	576.0	COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,1I085@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Mannitol dehydrogenase C-terminal domain	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k59_1299775_1	411154.GFO_3373	5.5e-135	410.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_678440_1	1347342.BN863_19860	9.1e-138	401.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_282934_1	1165841.SULAR_05243	7.83e-96	291.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2YN9H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1751635_5	1121899.Q764_06095	3.88e-18	82.8	2EJ7T@1|root,2ZY6P@2|Bacteria,4PCNZ@976|Bacteroidetes,1ID7R@117743|Flavobacteriia,2NXMQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_960808_2	156889.Mmc1_0312	6.51e-37	132.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1751646_1	1232410.KI421412_gene307	5.54e-81	253.0	2B8GB@1|root,321RF@2|Bacteria,1RIVE@1224|Proteobacteria,42SWQ@68525|delta/epsilon subdivisions,2WPWX@28221|Deltaproteobacteria,43V4P@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_678461_1	1565129.JSFF01000028_gene705	5.46e-33	119.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,2Q98N@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	OMPdecase
k59_678461_2	1565129.JSFF01000028_gene704	1.23e-32	120.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,2Q9ZD@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_282962_1	426114.THI_2487	5.3e-15	70.9	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KJVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	synthase small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_282962_2	686340.Metal_2418	1.65e-20	85.5	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1S4VI@1236|Gammaproteobacteria,1XF76@135618|Methylococcales	135618|Methylococcales	O	PFAM Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_170116_1	1123514.KB905899_gene697	1.29e-37	130.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,1SEFI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_170116_2	1168067.JAGP01000001_gene1926	3.46e-246	678.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,4609K@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_470799_1	90814.KL370892_gene2336	1.95e-204	607.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1600729_1	1121931.AUHG01000016_gene1025	1.82e-116	342.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1HXZV@117743|Flavobacteriia	976|Bacteroidetes	EGP	major facilitator	araJ	-	-	ko:K08156	-	-	-	-	ko00000,ko02000	2.A.1.2.14	-	-	MFS_1,Sugar_tr
k59_1542460_1	1442598.JABW01000027_gene910	5.4e-10	58.2	COG2120@1|root,COG2120@2|Bacteria,1PDXV@1224|Proteobacteria,42PK5@68525|delta/epsilon subdivisions,2YNRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_1542460_2	235909.GK3125	2.75e-37	135.0	COG0223@1|root,COG0223@2|Bacteria,1UZH4@1239|Firmicutes,4HF0N@91061|Bacilli,1WHCU@129337|Geobacillus	91061|Bacilli	J	Formyl transferase, C-terminal domain	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_865480_1	1123518.ARWI01000001_gene1420	4.49e-146	425.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,461XX@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_413815_1	1353276.JADR01000001_gene530	3.48e-120	349.0	COG1091@1|root,COG1091@2|Bacteria,4NF71@976|Bacteroidetes,1HZ17@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_697273_1	572480.Arnit_2089	1.63e-112	325.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2YP4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	methyltransferase	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
k59_640079_1	1123514.KB905899_gene1224	9.38e-109	335.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_1429942_1	90814.KL370891_gene390	2.42e-96	303.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales	72273|Thiotrichales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_921464_1	1565129.JSFF01000043_gene1595	1.61e-170	481.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,2QAP8@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iJN746.PP_4169,iSFV_1184.SFV_3923	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1146989_2	929558.SMGD1_0730	4.09e-87	260.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2YMTM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_130873_1	1123514.KB905902_gene310	8.15e-64	203.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,460J8@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_130873_2	1123514.KB905902_gene309	1.39e-171	487.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,460JC@72273|Thiotrichales	72273|Thiotrichales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_1090409_1	929558.SMGD1_2169	8.18e-76	234.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2YMDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_1090409_2	326298.Suden_0668	3.68e-20	87.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2YMP6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_1487245_1	588596.E2JE52	8.59e-11	64.7	COG1007@1|root,KOG4668@2759|Eukaryota,38F5W@33154|Opisthokonta,3NZK6@4751|Fungi	4751|Fungi	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	LAGLIDADG_1,NADH5_C,Proton_antipo_M,Proton_antipo_N
k59_697284_1	1158292.JPOE01000005_gene18	5.98e-23	97.4	COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,2VVU0@28216|Betaproteobacteria,1KMNB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
k59_697284_2	384676.PSEEN1997	1.95e-35	140.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,UvrD-helicase,UvrD_C
k59_809606_1	1121931.AUHG01000011_gene2131	1.21e-108	315.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1HY9T@117743|Flavobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_809606_2	411154.GFO_2250	3.52e-112	336.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia	976|Bacteroidetes	C	dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_470856_1	323850.Shew_1824	8.43e-106	308.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,2Q9X3@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein LuxR	uvrY	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_865518_1	326298.Suden_0870	7.87e-33	125.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_865518_2	326298.Suden_0869	3.58e-176	495.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2YMC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_865520_1	1380600.AUYN01000006_gene702	2.56e-213	613.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1HWZI@117743|Flavobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_188507_1	411154.GFO_2199	2.6e-98	295.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,1HWT1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0798 Arsenite efflux pump ACR3 and related	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_300989_1	1056820.KB900640_gene285	5.77e-13	68.2	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,2PQ7K@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_300989_2	944547.ABLL_0539	1.37e-96	309.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,42P5C@68525|delta/epsilon subdivisions,2YNRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75542_1	1042375.AFPL01000046_gene1898	2.83e-30	116.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Sarcosine oxidase, subunit beta	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
k59_75542_2	317025.Tcr_1350	9.76e-36	123.0	COG4311@1|root,COG4311@2|Bacteria,1NA4N@1224|Proteobacteria,1SG2K@1236|Gammaproteobacteria,4635X@72273|Thiotrichales	72273|Thiotrichales	E	Sarcosine oxidase, delta subunit family	-	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
k59_75542_3	317025.Tcr_1349	1.66e-82	270.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,461P3@72273|Thiotrichales	72273|Thiotrichales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
k59_413866_1	411154.GFO_0145	3e-174	516.0	COG0477@1|root,COG0477@2|Bacteria,4PM7N@976|Bacteroidetes,1IJKR@117743|Flavobacteriia	976|Bacteroidetes	EGP	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_1035017_1	1178825.ALIH01000006_gene1457	7.32e-37	135.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,1HY29@117743|Flavobacteriia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
k59_413868_1	1249627.D779_4233	8.85e-104	320.0	2C69V@1|root,2Z9DY@2|Bacteria,1R5H6@1224|Proteobacteria,1RZY0@1236|Gammaproteobacteria,1WXUP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130913_1	1123228.AUIH01000029_gene3396	6.56e-72	222.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XJNP@135619|Oceanospirillales	135619|Oceanospirillales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_188527_1	1121931.AUHG01000018_gene1386	3.33e-162	477.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_1713344_1	880070.Cycma_4345	1.25e-14	67.4	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1713344_2	880070.Cycma_4345	3.21e-31	110.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1770059_1	929558.SMGD1_0132	2.44e-71	238.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03090,ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	CHASE,CheX,GAF,GGDEF,PAS_8,Response_reg,cNMP_binding
k59_1487311_1	1123228.AUIH01000019_gene3683	1.46e-60	191.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1XIEM@135619|Oceanospirillales	135619|Oceanospirillales	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_75580_1	1123037.AUDE01000027_gene2097	8.93e-97	305.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_188539_1	326298.Suden_0132	2.21e-29	108.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_188539_2	326298.Suden_0131	3.11e-23	96.3	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2YMXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_640157_1	929558.SMGD1_1101	2.36e-54	176.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SZP@68525|delta/epsilon subdivisions,2YSYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_640157_2	929558.SMGD1_1100	6.17e-105	316.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,43CMA@68525|delta/epsilon subdivisions,2YRH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_865571_1	90814.KL370891_gene1303	1.01e-29	114.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,45ZV7@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_865571_2	1123514.KB905899_gene1130	8.34e-91	267.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,460J0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k59_865571_3	90814.KL370891_gene1301	2.6e-59	187.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,4616R@72273|Thiotrichales	72273|Thiotrichales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_1542560_1	572480.Arnit_0379	2.08e-94	289.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_413905_1	1123517.JOMR01000001_gene994	3.92e-24	93.6	2DCMK@1|root,2ZENF@2|Bacteria,1PACB@1224|Proteobacteria,1SW0Y@1236|Gammaproteobacteria,46385@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_413905_2	1123518.ARWI01000001_gene115	6.32e-71	218.0	COG0664@1|root,COG0664@2|Bacteria,1NPK3@1224|Proteobacteria	1224|Proteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_413905_3	90814.KL370891_gene1166	4.08e-24	102.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,4603A@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_1260682_1	1137281.D778_01910	5.95e-214	597.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1HX0F@117743|Flavobacteriia	976|Bacteroidetes	O	collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1260682_2	1178825.ALIH01000009_gene1363	3.62e-40	133.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,1I3ZD@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S ferredoxin	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
k59_17440_2	1121918.ARWE01000001_gene158	5.37e-85	270.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,43TFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	sfrB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_1373134_1	1353276.JADR01000002_gene2254	1.18e-36	134.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1HX67@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
k59_1373134_2	1380600.AUYN01000007_gene3172	9.55e-73	220.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1I2VE@117743|Flavobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_356554_1	572480.Arnit_2605	2.34e-91	285.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2YN08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_188574_1	411154.GFO_1004	2.43e-67	213.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1HWW9@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
k59_188574_2	411154.GFO_1005	5.79e-56	180.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1HY9K@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1713394_1	1121912.AUHD01000001_gene2755	1.46e-81	253.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1HWUF@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
k59_1713394_2	1137281.D778_00368	1.71e-219	611.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1HXH7@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1600873_1	880073.Calab_0922	2.47e-12	67.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
k59_1487360_1	1121931.AUHG01000010_gene73	2.11e-108	327.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_356561_1	504487.JCM19302_2230	1.5e-06	47.4	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_356561_2	1137281.D778_00532	4.04e-100	321.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
k59_1430067_1	225849.swp_2644	3.05e-40	152.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,2Q8H4@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_75635_1	497321.C664_18332	1.62e-100	299.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,2KW79@206389|Rhodocyclales	206389|Rhodocyclales	NU	type 4 pilus biogenesis protein	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
k59_975479_1	1565129.JSFF01000012_gene526	7.43e-22	91.7	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,2QAF2@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
k59_975479_2	323850.Shew_3500	4.11e-77	230.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,2QBMG@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_245081_1	1158292.JPOE01000002_gene2549	1.36e-17	80.9	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_245081_2	1123228.AUIH01000005_gene743	3.59e-68	216.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1XK89@135619|Oceanospirillales	135619|Oceanospirillales	N	Flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1430078_1	367737.Abu_0164	6.99e-55	180.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2YMXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1430078_2	572480.Arnit_0313	1.74e-40	137.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,42RXC@68525|delta/epsilon subdivisions,2YP4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	esterase of the alpha beta hydrolase fold	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
k59_1487376_1	1178825.ALIH01000005_gene162	1.72e-101	300.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,1HY5I@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
k59_1487376_2	1250005.PHEL85_0101	1.93e-82	271.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia,3VW2R@52959|Polaribacter	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k59_752206_1	929558.SMGD1_1073	4.8e-144	420.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2YRHY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
k59_1489884_2	1237149.C900_02552	4.16e-29	108.0	2ENX1@1|root,33GHZ@2|Bacteria,4NXFU@976|Bacteroidetes,47WQI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_358929_1	313595.P700755_003215	6.41e-176	501.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,4C434@83612|Psychroflexus	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_358929_2	1484460.JSWG01000001_gene2155	7.86e-32	120.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,1HYCH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1375495_1	319224.Sputcn32_3455	7.37e-39	136.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,2QABZ@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	lafA	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_473568_1	396588.Tgr7_1430	2.92e-41	144.0	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria,1WY2H@135613|Chromatiales	135613|Chromatiales	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_1093004_1	411154.GFO_3412	1.24e-18	85.1	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1093004_2	411154.GFO_3411	3.32e-88	265.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_754546_1	572480.Arnit_2908	3.45e-17	75.1	29BUT@1|root,2ZYT3@2|Bacteria,1Q552@1224|Proteobacteria,430JR@68525|delta/epsilon subdivisions,2YS3W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_754546_2	387093.SUN_0706	1.93e-51	164.0	COG5652@1|root,COG5652@2|Bacteria,1RDK4@1224|Proteobacteria,42WR9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_754546_3	387093.SUN_0707	4.81e-42	141.0	COG4190@1|root,COG4190@2|Bacteria,1RDM2@1224|Proteobacteria,42UER@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR,MarR
k59_1544881_1	1229276.DI53_1892	1.32e-21	94.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IP3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1544881_2	563040.Saut_0258	8.07e-56	178.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42P3W@68525|delta/epsilon subdivisions,2YMZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_977411_1	709032.Sulku_1517	6.79e-67	222.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_1716033_1	90814.KL370891_gene518	2.12e-212	592.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1716033_2	1123518.ARWI01000001_gene799	1.73e-124	358.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,460GB@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Cytochrome C1	-	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_1716033_3	90814.KL370891_gene522	1.72e-115	343.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,45ZQZ@72273|Thiotrichales	72273|Thiotrichales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
k59_923939_1	411154.GFO_2811	1.81e-49	162.0	2AVE1@1|root,31M5W@2|Bacteria,4NS2G@976|Bacteroidetes,1I4MZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
k59_425310_2	316067.Geob_0928	4.03e-08	52.0	294M8@1|root,34B0H@2|Bacteria,1P2RM@1224|Proteobacteria,43174@68525|delta/epsilon subdivisions,2WWJZ@28221|Deltaproteobacteria,43VJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_651565_1	714943.Mucpa_1281	4.8e-67	227.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_142083_1	1347342.BN863_4650	3.94e-103	305.0	COG2321@1|root,COG2321@2|Bacteria,4NDTZ@976|Bacteroidetes,1HXEW@117743|Flavobacteriia	976|Bacteroidetes	S	metalloprotease	ypfJ	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
k59_1668238_1	1121897.AUGO01000007_gene476	6.22e-37	127.0	COG3832@1|root,COG3832@2|Bacteria,4NN6Z@976|Bacteroidetes,1IMHG@117743|Flavobacteriia,2P0C8@237|Flavobacterium	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_1668238_2	1123248.KB893357_gene4696	8.71e-64	198.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1ISV0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM 3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
k59_1668238_3	991.IW20_23335	2.98e-126	366.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,1HZKB@117743|Flavobacteriia,2NUZP@237|Flavobacterium	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_710169_2	326298.Suden_1125	3.93e-89	264.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2YP4R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_710169_3	326298.Suden_1126	1.32e-09	56.6	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2YT63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_1384215_1	1172190.M947_00050	4.57e-87	266.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_425333_1	1380600.AUYN01000009_gene1003	6.98e-231	659.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_425333_2	1178825.ALIH01000007_gene1614	5.5e-33	124.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1HXE0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_367880_1	929562.Emtol_2016	1.37e-39	145.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,47M8R@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_367880_2	382464.ABSI01000011_gene3135	9.33e-23	92.8	COG0315@1|root,COG0315@2|Bacteria,46VUN@74201|Verrucomicrobia,2IUS5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	MoaC family	-	-	-	-	-	-	-	-	-	-	-	-	MoaC
k59_1782093_1	574966.KB898650_gene564	7.46e-99	294.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RSPV@1236|Gammaproteobacteria,1XN6C@135619|Oceanospirillales	135619|Oceanospirillales	E	Branched-chain amino acid ABC transporter ATPase	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_985020_2	511062.GU3_08615	4.09e-39	134.0	COG3108@1|root,COG3108@2|Bacteria,1N6F7@1224|Proteobacteria,1SBQ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
k59_985020_3	983917.RGE_17400	8.21e-05	48.1	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VQJ3@28216|Betaproteobacteria,1KJC2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
k59_89503_2	1046627.BZARG_844	4.13e-167	473.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1HYBW@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleoid-associated protein NdpA	-	-	-	-	-	-	-	-	-	-	-	-	NA37
k59_259599_1	317025.Tcr_0289	1.1e-210	622.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_934909_1	1565129.JSFF01000017_gene2920	4.4e-97	295.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,2Q8ZS@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM serine dehydratase alpha chain	sdaA	GO:0003674,GO:0003824,GO:0003941,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_2106	SDH_alpha,SDH_beta
k59_144844_1	580332.Slit_0621	1.79e-20	94.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,44UZ9@713636|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_202604_1	395493.BegalDRAFT_3330	2.15e-29	110.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,460MP@72273|Thiotrichales	72273|Thiotrichales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_202604_2	118797.XP_007451680.1	1.43e-15	76.6	COG0441@1|root,KOG1637@2759|Eukaryota,38C5Y@33154|Opisthokonta,3B9Y5@33208|Metazoa,3CVGA@33213|Bilateria,4843X@7711|Chordata	33208|Metazoa	J	threonine-tRNA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	IF3_C,IF3_N,tRNA-synt_2b,tRNA_SAD
k59_1333483_1	1121931.AUHG01000011_gene1990	4.12e-60	188.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_1333483_2	1121931.AUHG01000011_gene1989	8.88e-268	773.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1784753_1	765913.ThidrDRAFT_4499	1.14e-89	279.0	COG1879@1|root,COG1879@2|Bacteria,1MXQN@1224|Proteobacteria,1S2J6@1236|Gammaproteobacteria,1X0YT@135613|Chromatiales	135613|Chromatiales	G	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_1,Peripla_BP_4
k59_1671081_1	945713.IALB_1440	2.29e-45	165.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_2160,iPC815.YPO2428	B3_4,B5,FDX-ACB,tRNA_bind
k59_30951_2	1123392.AQWL01000007_gene984	2.51e-54	183.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,2VJFD@28216|Betaproteobacteria,1KRCB@119069|Hydrogenophilales	119069|Hydrogenophilales	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct
k59_1727427_1	572480.Arnit_0134	2.34e-104	314.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_1161599_1	563040.Saut_1598	4.44e-83	249.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1161599_2	709032.Sulku_1291	2.11e-88	269.0	COG1879@1|root,COG1879@2|Bacteria,1Q695@1224|Proteobacteria,43ABX@68525|delta/epsilon subdivisions,2YR8J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_1727430_2	269799.Gmet_3564	1.43e-12	61.6	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,42WSU@68525|delta/epsilon subdivisions,2WSI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k59_1784773_2	1250278.JQNQ01000001_gene2277	1.07e-71	226.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia	976|Bacteroidetes	S	Sodium bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_1208843_1	945713.IALB_0554	7.07e-18	77.4	2BWJ4@1|root,2ZMM0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_713156_1	1121931.AUHG01000016_gene1124	1.78e-22	90.1	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1I2AQ@117743|Flavobacteriia	976|Bacteroidetes	S	glyoxalase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
k59_713156_2	1121931.AUHG01000016_gene1125	1.15e-26	103.0	28NAV@1|root,2ZBEH@2|Bacteria,4NJGP@976|Bacteroidetes,1I0G3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_202653_2	1056816.JAFQ01000004_gene5872	7.16e-07	50.8	COG1123@1|root,COG4172@2|Bacteria,2HHSV@201174|Actinobacteria,4G04F@85025|Nocardiaceae	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
k59_1556508_2	1178825.ALIH01000013_gene535	1.29e-08	54.7	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1502109_1	1249627.D779_3943	3.15e-59	197.0	COG3316@1|root,COG3316@2|Bacteria,1QE29@1224|Proteobacteria,1T5ZZ@1236|Gammaproteobacteria,1X2WN@135613|Chromatiales	135613|Chromatiales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_1161623_1	90814.KL370891_gene765	6.03e-80	245.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,45ZZD@72273|Thiotrichales	72273|Thiotrichales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_1161623_2	317025.Tcr_0710	5.56e-132	380.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,45ZQP@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_654401_1	563040.Saut_0944	1.06e-121	360.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_654401_2	929558.SMGD1_2548	1.42e-81	248.0	COG0596@1|root,COG0596@2|Bacteria,1NH3R@1224|Proteobacteria,42R8Q@68525|delta/epsilon subdivisions,2YNWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_1556528_1	616991.JPOO01000003_gene580	8.85e-105	338.0	COG1073@1|root,COG1073@2|Bacteria,4NID3@976|Bacteroidetes,1I78I@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
k59_1333547_1	313603.FB2170_01597	2.91e-87	261.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia,2PHBI@252356|Maribacter	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_1333547_2	1178825.ALIH01000019_gene1252	1.99e-101	300.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1671143_1	1336233.JAEH01000011_gene2885	4.66e-72	220.0	COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,1S3WV@1236|Gammaproteobacteria,2QBTR@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Belongs to the glutathione peroxidase family	gpwA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_1274929_1	563040.Saut_1333	1.94e-161	466.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1274930_1	323850.Shew_3271	1.45e-93	285.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,2Q9HT@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k59_1048784_1	1408473.JHXO01000002_gene3986	2.43e-44	151.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_713207_2	1123518.ARWI01000001_gene1476	4.37e-151	436.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,45ZQ5@72273|Thiotrichales	72273|Thiotrichales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_1556555_1	351016.RAZWK3B_05962	3.63e-41	146.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2P1Y2@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	ppsC	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1387170_1	1249480.B649_10060	5.15e-37	142.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_144957_1	1046627.BZARG_1733	4.94e-98	299.0	COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,1HY19@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
k59_202717_1	760192.Halhy_1822	5.06e-115	347.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1IPFW@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0374 Ni Fe-hydrogenase I large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1104791_1	1168067.JAGP01000001_gene1807	3.29e-110	325.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4601Z@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1727509_1	1121931.AUHG01000011_gene2182	8.37e-96	280.0	2DBYA@1|root,2ZBU9@2|Bacteria,4NNGM@976|Bacteroidetes,1I19X@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1727509_2	1121859.KB890755_gene1273	1.4e-63	202.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_1104793_1	411154.GFO_3263	2.66e-141	412.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_935022_1	411154.GFO_2233	1.06e-185	538.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia	976|Bacteroidetes	E	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_1104799_1	1123518.ARWI01000001_gene1236	2.06e-36	138.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,4600P@72273|Thiotrichales	72273|Thiotrichales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1104799_2	1123514.KB905899_gene1981	3.8e-28	109.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,460DA@72273|Thiotrichales	72273|Thiotrichales	Q	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_31060_1	1499967.BAYZ01000186_gene3988	2.07e-09	61.6	COG0840@1|root,COG0840@2|Bacteria,2NQS9@2323|unclassified Bacteria	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	cheD2	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k59_1556602_1	572480.Arnit_2117	7e-77	237.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42Q58@68525|delta/epsilon subdivisions,2YNDQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_1556602_2	990073.ATHU01000003_gene1836	1.08e-20	85.1	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_713264_1	929558.SMGD1_1909	4.45e-89	266.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YMRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_713264_2	929558.SMGD1_1910	1.14e-53	170.0	2BQIT@1|root,32JEK@2|Bacteria,1Q29V@1224|Proteobacteria,42V8T@68525|delta/epsilon subdivisions,2YQEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_713264_3	929558.SMGD1_1911	7.99e-90	266.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2YRMZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_766296_1	28229.ND2E_2593	9.83e-40	145.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,2Q75F@267889|Colwelliaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_879862_1	1869.MB27_36140	3.58e-16	83.6	COG0840@1|root,COG0840@2|Bacteria,2H2QC@201174|Actinobacteria	201174|Actinobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_825060_1	945713.IALB_2221	1.21e-07	49.3	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_825060_2	1168034.FH5T_20115	1.21e-45	152.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,2FQV3@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_935069_1	1392490.JHZX01000001_gene586	1.25e-82	263.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_879877_1	1392489.JPOL01000002_gene2703	4.45e-104	315.0	COG0707@1|root,COG0707@2|Bacteria,4PKUP@976|Bacteroidetes,1IJFS@117743|Flavobacteriia,2XIN2@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf,MGDG_synth
k59_1275030_1	411154.GFO_2758	2.51e-222	616.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1HXC6@117743|Flavobacteriia	976|Bacteroidetes	V	proteins, homologs of microcin C7 resistance protein MccF	ldcA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_1275030_2	411154.GFO_2757	8.92e-50	169.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HY7E@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_1104868_1	983544.Lacal_0343	5.54e-131	386.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1HX0N@117743|Flavobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1275037_1	1123518.ARWI01000001_gene1065	1.46e-37	135.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,460C1@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_1275037_2	1123518.ARWI01000001_gene1064	4.59e-56	177.0	COG2832@1|root,COG2832@2|Bacteria,1QSH3@1224|Proteobacteria,1RVXA@1236|Gammaproteobacteria,462VY@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
k59_1671260_1	572480.Arnit_0817	2.67e-177	526.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_935088_1	1380600.AUYN01000006_gene364	2.78e-138	401.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1HWX7@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_1502267_1	1336233.JAEH01000064_gene2531	2.53e-80	255.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,2QAB7@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DEAD DEAH box helicase domain protein	yejH	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k59_202827_1	1123514.KB905899_gene1492	3.4e-48	159.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,460YW@72273|Thiotrichales	72273|Thiotrichales	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_202827_2	246197.MXAN_2055	2.06e-12	66.6	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_1387285_1	929558.SMGD1_1830	1.43e-112	331.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2YMR8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_879925_1	1232410.KI421413_gene663	5.8e-63	216.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,43SAV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1237570_1	497321.C664_10582	2.21e-12	69.3	COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,2VK4Q@28216|Betaproteobacteria,2KWIR@206389|Rhodocyclales	206389|Rhodocyclales	L	Mu transposase, C-terminal	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Mu-transpos_C,rve
k59_959934_1	1004149.AFOE01000012_gene1526	1.73e-107	317.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1HWYJ@117743|Flavobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_959934_2	1032480.MLP_49070	0.000431	50.4	COG2273@1|root,COG2273@2|Bacteria,2GNRK@201174|Actinobacteria,4DV8Y@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_959934_3	1178825.ALIH01000003_gene2012	5.31e-150	424.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_959934_4	1046627.BZARG_1165	1.89e-21	88.2	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1HYRH@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_959953_1	877424.ATWC01000029_gene1653	2.74e-12	62.8	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia,27PH9@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k59_1637899_1	572480.Arnit_1454	1.47e-53	174.0	COG0639@1|root,COG0639@2|Bacteria,1N4BG@1224|Proteobacteria,42T7V@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	MA20_24125	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_1237681_1	411154.GFO_0216	6.68e-91	270.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia	976|Bacteroidetes	S	Acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1237681_2	411154.GFO_0215	4.81e-196	545.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1HY0R@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_1237681_3	1121931.AUHG01000010_gene866	8.83e-14	68.6	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,1I060@117743|Flavobacteriia	976|Bacteroidetes	M	Inorganic polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1637964_1	1123518.ARWI01000001_gene1021	1.35e-69	213.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,460ID@72273|Thiotrichales	72273|Thiotrichales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_1637964_2	1123518.ARWI01000001_gene1019	1.68e-15	71.6	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,460T4@72273|Thiotrichales	72273|Thiotrichales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_960137_1	1229753.K7QJU9_9CAUD	2.49e-42	157.0	4QGGQ@10239|Viruses,4QZHN@35237|dsDNA viruses  no RNA stage,4QUH3@28883|Caudovirales,4QJHH@10662|Myoviridae	10662|Myoviridae	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1237806_1	563040.Saut_1071	7.94e-134	396.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2YP81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_1237964_2	553385.JEMF01000020_gene3017	1.08e-29	119.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XIF9@135619|Oceanospirillales	135619|Oceanospirillales	E	Serine dehydratase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_1238267_1	1121931.AUHG01000010_gene589	3.67e-39	133.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,1I0V1@117743|Flavobacteriia	976|Bacteroidetes	S	Magnesium transporter MgtC	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
k59_1238267_2	411154.GFO_3561	1.91e-69	220.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1HY28@117743|Flavobacteriia	976|Bacteroidetes	H	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1238279_1	1121931.AUHG01000011_gene1652	8.57e-124	372.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1238345_1	1121887.AUDK01000018_gene3276	1.03e-55	179.0	COG1595@1|root,COG1595@2|Bacteria,4NQ2T@976|Bacteroidetes,1I399@117743|Flavobacteriia,2NV1B@237|Flavobacterium	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1238454_1	306263.Cla_1234	2.92e-85	265.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,42N4A@68525|delta/epsilon subdivisions,2YMSZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylglucosamine 2-epimerase	legG	GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576	3.2.1.184	ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
k59_1238544_1	1453501.JELR01000005_gene1681	6.02e-09	57.8	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,4646G@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0061 (SELO) family	ydiU	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
k59_1238626_1	411154.GFO_3322	1.3e-134	399.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,4PKJ5@976|Bacteroidetes,1HY50@117743|Flavobacteriia	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_1238898_1	1123518.ARWI01000001_gene249	4.13e-80	250.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,46067@72273|Thiotrichales	72273|Thiotrichales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1239003_1	1415778.JQMM01000001_gene1455	7.68e-69	212.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03969	-	-	-	-	ko00000	-	-	-	DUF4139,DUF4140,LRAT,PspA_IM30
k59_1239059_1	376686.Fjoh_1999	4.87e-140	404.0	COG1609@1|root,COG1609@2|Bacteria,4NKD4@976|Bacteroidetes,1I0J7@117743|Flavobacteriia,2NS63@237|Flavobacterium	976|Bacteroidetes	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
k59_1239059_2	1392490.JHZX01000001_gene732	5.22e-138	403.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,1HXH0@117743|Flavobacteriia	976|Bacteroidetes	G	Carbohydrate kinase	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1239734_1	929558.SMGD1_1765	4.1e-48	169.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1QU1X@1224|Proteobacteria	1224|Proteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K02480,ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,dCache_2,sCache_2
k59_1239783_1	1123514.KB905902_gene276	1.51e-31	127.0	2DRK8@1|root,33C5B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1239878_1	1121931.AUHG01000010_gene711	3.6e-58	191.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_1239878_2	388413.ALPR1_05860	2.14e-26	101.0	COG0454@1|root,COG0456@2|Bacteria,4NSPT@976|Bacteroidetes,47RPU@768503|Cytophagia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
k59_1239919_1	323850.Shew_1094	6.25e-74	236.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,1RN9P@1236|Gammaproteobacteria,2Q9AS@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1239991_1	595494.Tola_1286	1.03e-16	80.5	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
k59_1239991_2	1172190.M947_10275	3.5e-59	192.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP1346	Gp_dh_C,Gp_dh_N
k59_1240126_1	1123248.KB893337_gene2430	5.75e-62	212.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1IPJ8@117747|Sphingobacteriia	976|Bacteroidetes	DM	PFAM lipopolysaccharide biosynthesis	epsB	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_1240729_1	929558.SMGD1_1286	7.62e-121	369.0	COG3144@1|root,COG3144@2|Bacteria,1PBUJ@1224|Proteobacteria,42VQM@68525|delta/epsilon subdivisions,2YQGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_1240784_2	1121931.AUHG01000010_gene304	1.45e-66	208.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1HY9V@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_1240842_1	1172190.M947_08660	1.83e-61	211.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1241052_1	1123228.AUIH01000010_gene4002	1.17e-52	177.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1XPHQ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1241122_1	661367.LLO_2493	2.51e-13	72.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1JDEZ@118969|Legionellales	118969|Legionellales	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_1241122_2	929558.SMGD1_1086	4.21e-146	429.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1241277_1	929558.SMGD1_0138	1.3e-129	393.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1241560_1	323850.Shew_0025	6.7e-93	274.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,2QBBY@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Flavodoxin domain	hemG	GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3850,iAPECO1_1312.APECO1_2607,iB21_1397.B21_03690,iBWG_1329.BWG_3526,iE2348C_1286.E2348C_4162,iECABU_c1320.ECABU_c43520,iECBD_1354.ECBD_4175,iECB_1328.ECB_03741,iECDH10B_1368.ECDH10B_4039,iECDH1ME8569_1439.ECDH1ME8569_3727,iECD_1391.ECD_03741,iECED1_1282.ECED1_4552,iECH74115_1262.ECH74115_5289,iECIAI1_1343.ECIAI1_4043,iECNA114_1301.ECNA114_4159,iECOK1_1307.ECOK1_4319,iECS88_1305.ECS88_4298,iECSF_1327.ECSF_3707,iECSP_1301.ECSP_4903,iECs_1301.ECs4778,iEcDH1_1363.EcDH1_4131,iEcHS_1320.EcHS_A4073,iEcolC_1368.EcolC_4160,iG2583_1286.G2583_4648,iJO1366.b3850,iJR904.b3850,iLF82_1304.LF82_0981,iNRG857_1313.NRG857_19220,iSDY_1059.SDY_3895,iUMN146_1321.UM146_19505,iUMNK88_1353.UMNK88_4678,iUTI89_1310.UTI89_C4435,iY75_1357.Y75_RS17835,iZ_1308.Z5372,ic_1306.c4797	Flavodoxin_5
k59_1242254_1	1123518.ARWI01000001_gene1825	9e-56	179.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1S5D0@1236|Gammaproteobacteria,462MD@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k59_1242254_2	1123514.KB905899_gene1787	2.73e-103	314.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,46219@72273|Thiotrichales	72273|Thiotrichales	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_1242273_1	29495.EA26_08050	7.17e-67	211.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XT06@135623|Vibrionales	135623|Vibrionales	H	Riboflavin synthase alpha chain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1242469_1	1380600.AUYN01000007_gene3329	1.62e-201	571.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_1242469_2	1443665.JACA01000097_gene3982	2.27e-23	98.2	COG5661@1|root,COG5661@2|Bacteria,4PAPH@976|Bacteroidetes,1ICHT@117743|Flavobacteriia,2YM32@290174|Aquimarina	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1242469_3	1178825.ALIH01000003_gene2073	5.09e-104	305.0	COG0492@1|root,COG0492@2|Bacteria,4NHKD@976|Bacteroidetes,1I1D6@117743|Flavobacteriia	976|Bacteroidetes	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_1242469_4	504487.JCM19302_1472	5.52e-13	64.3	2C4ZA@1|root,3346C@2|Bacteria,4NVPK@976|Bacteroidetes,1I5SW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1242469_5	1380600.AUYN01000007_gene3332	1.15e-105	309.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia	976|Bacteroidetes	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_1242469_6	926559.JoomaDRAFT_1479	3.88e-43	145.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
k59_1242630_1	1178825.ALIH01000008_gene804	2.16e-58	183.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_1242630_2	1380600.AUYN01000006_gene291	1.27e-180	506.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1HWZ0@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_1242630_3	1380600.AUYN01000006_gene290	8e-44	144.0	2C8IP@1|root,32RM9@2|Bacteria,4NSFN@976|Bacteroidetes,1I40E@117743|Flavobacteriia	976|Bacteroidetes	-	-	mraW	-	-	-	-	-	-	-	-	-	-	-	-
k59_736099_1	504487.JCM19302_3361	1.46e-80	244.0	2BZRU@1|root,34BWD@2|Bacteria,4P6IU@976|Bacteroidetes,1IABW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1752878_1	1123514.KB905899_gene912	4.49e-64	202.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,1SYJC@1236|Gammaproteobacteria,4607A@72273|Thiotrichales	72273|Thiotrichales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1752878_2	1123518.ARWI01000001_gene108	5.87e-34	124.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,45ZR0@72273|Thiotrichales	72273|Thiotrichales	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_1131586_1	1178825.ALIH01000012_gene1799	5.05e-30	114.0	COG2035@1|root,COG2035@2|Bacteria,4NDU1@976|Bacteroidetes,1HYB3@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF368
k59_1131586_2	1380600.AUYN01000001_gene2697	1.09e-59	192.0	COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,1HYAC@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
k59_736117_1	1237149.C900_04576	5.86e-96	305.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_171309_1	944547.ABLL_0044	2.03e-25	97.4	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,42TEY@68525|delta/epsilon subdivisions,2YPN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_171309_2	572480.Arnit_0060	1.8e-96	283.0	COG0716@1|root,COG0716@2|Bacteria,1QRBW@1224|Proteobacteria	1224|Proteobacteria	C	Low-potential electron donor to a number of redox enzymes	isiB	-	-	ko:K03839,ko:K03840	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_171309_3	944547.ABLL_0042	1.04e-53	170.0	2E67S@1|root,32Q79@2|Bacteria,1N05A@1224|Proteobacteria,42X30@68525|delta/epsilon subdivisions,2YQVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein NifW	-	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_171309_4	572480.Arnit_0058	1.5e-77	232.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	prsA	-	5.2.1.8	ko:K02597,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	NifZ,Rotamase,Rotamase_2,Rotamase_3
k59_171309_5	760154.Sulba_1013	1.81e-27	102.0	COG0633@1|root,COG0633@2|Bacteria,1PSR6@1224|Proteobacteria,42XGK@68525|delta/epsilon subdivisions,2YQWI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_509660_2	563040.Saut_0845	1.07e-116	342.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2YMRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_340399_1	1121912.AUHD01000011_gene717	2.71e-230	642.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWJZ@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1357131_1	1121012.AUKX01000036_gene778	1.39e-71	244.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1IJMW@117743|Flavobacteriia,23I2Y@178469|Arenibacter	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,HisKA_7TM,Hpt,PAS,PAS_3,PAS_8,PAS_9,Response_reg
k59_453751_1	1123228.AUIH01000002_gene1428	9.8e-96	283.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XIPY@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
k59_1752911_1	709032.Sulku_1670	4.31e-41	144.0	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	709032.Sulku_1670|-	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1752911_2	97139.C824_04168	1.38e-26	108.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,36HPB@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_962025_1	929558.SMGD1_2589	6e-50	160.0	COG1886@1|root,COG1886@2|Bacteria,1NNYT@1224|Proteobacteria,42U38@68525|delta/epsilon subdivisions,2YPTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_962025_2	1172190.M947_00885	3.03e-55	176.0	2AJ5D@1|root,319PZ@2|Bacteria,1Q3HS@1224|Proteobacteria,42XCD@68525|delta/epsilon subdivisions,2YQQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_340417_1	1249975.JQLP01000001_gene3132	1.97e-75	236.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1HXUV@117743|Flavobacteriia,2P5XM@244698|Gillisia	976|Bacteroidetes	H	Ferrochelatase	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_736152_1	411154.GFO_2523	8.83e-121	354.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1HWV8@117743|Flavobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_171347_1	1235457.C404_04465	1.7e-91	299.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria,1K20Q@119060|Burkholderiaceae	28216|Betaproteobacteria	E	NAD-glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_453778_1	572480.Arnit_0939	1.44e-123	364.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2YMZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_453778_2	572480.Arnit_0940	3.32e-10	58.5	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,42QUT@68525|delta/epsilon subdivisions,2YNVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_397283_2	1519464.HY22_04545	0.000137	43.5	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSII_BNR,fn3
k59_1640058_1	1392490.JHZX01000001_gene2721	5.71e-15	83.2	COG1196@1|root,COG3064@1|root,COG1196@2|Bacteria,COG3064@2|Bacteria,4NGJZ@976|Bacteroidetes,1HY5X@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	sprD	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF,SPOR
k59_1991_1	688270.Celal_3003	9.97e-136	400.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HY6N@117743|Flavobacteriia,1FA81@104264|Cellulophaga	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1991_2	641526.ADIWIN_3215	6.44e-83	247.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_72735_2	563040.Saut_0589	1.8e-217	616.0	COG1511@1|root,COG2199@1|root,COG1511@2|Bacteria,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1540073_1	1121459.AQXE01000006_gene209	1.46e-10	64.7	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2M81W@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_862904_1	700598.Niako_6619	7.14e-13	67.8	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_862904_2	90814.KL370891_gene1151	2.46e-85	268.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,460AB@72273|Thiotrichales	72273|Thiotrichales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1540074_1	1168289.AJKI01000012_gene302	7.99e-07	51.2	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,2FP5Y@200643|Bacteroidia,3XJ3P@558415|Marinilabiliaceae	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	fdtC	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_1540074_2	1033734.CAET01000039_gene323	2.4e-37	130.0	COG1898@1|root,COG1898@2|Bacteria,1V3X4@1239|Firmicutes,4HY26@91061|Bacilli,1ZIBI@1386|Bacillus	91061|Bacilli	M	WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,FdtA
k59_694574_1	1172190.M947_04965	9.17e-31	125.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1370428_1	1232410.KI421424_gene1780	5.18e-66	203.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42UPV@68525|delta/epsilon subdivisions,2WQB6@28221|Deltaproteobacteria,43UXF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_411289_1	1123514.KB905903_gene341	2.68e-122	361.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,45ZY4@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_354035_1	398579.Spea_2444	3.29e-12	66.2	COG0850@1|root,COG0850@2|Bacteria,1RHVN@1224|Proteobacteria,1S6K8@1236|Gammaproteobacteria,2QES9@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007346,GO:0008150,GO:0009987,GO:0010564,GO:0032465,GO:0032954,GO:0032955,GO:0042802,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051726,GO:0060187,GO:0065007,GO:1901891,GO:1902412,GO:1903436	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
k59_354035_2	1168065.DOK_15738	5.95e-42	144.0	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,1RNJ0@1236|Gammaproteobacteria,1J5BF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the ParA family	minD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007059,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051782,GO:0060187,GO:0065007,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_354038_1	1380600.AUYN01000003_gene44	1.66e-07	50.8	COG1247@1|root,COG1247@2|Bacteria,4NPIE@976|Bacteroidetes,1I2DZ@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphinothricin acetyltransferase	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
k59_354038_2	313603.FB2170_01070	2.64e-76	232.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia,2PHAB@252356|Maribacter	976|Bacteroidetes	S	Mycothiol maleylpyruvate isomerase N-terminal domain	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_524000_1	929558.SMGD1_1576	8.48e-15	73.2	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_524000_2	1172190.M947_06245	1.53e-77	249.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S84@68525|delta/epsilon subdivisions,2YPD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1484652_1	1121931.AUHG01000017_gene1542	9.23e-128	367.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1HWXB@117743|Flavobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_354043_1	572480.Arnit_2574	1.98e-80	249.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2YMID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1427521_1	1453505.JASY01000001_gene3428	4.58e-31	120.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,1HZWV@117743|Flavobacteriia,2NSQ2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1370452_1	1123518.ARWI01000001_gene1643	7.11e-78	246.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,45ZSX@72273|Thiotrichales	72273|Thiotrichales	NU	Type II IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1144591_1	56110.Oscil6304_1714	2.34e-31	119.0	COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HFC1@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1144591_2	768670.Calni_1798	1.95e-14	76.6	COG0399@1|root,COG0399@2|Bacteria,2GF7R@200930|Deferribacteres	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_14995_1	1380600.AUYN01000009_gene2142	5.51e-68	211.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,1HXBY@117743|Flavobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_14995_2	760011.Spico_0892	0.000261	44.3	COG1012@1|root,COG1012@2|Bacteria,2J5FJ@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the aldehyde dehydrogenase family	ywdH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_694613_1	1123514.KB905902_gene301	1.83e-140	401.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,4606J@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k59_1258074_1	283699.D172_0991	2.72e-23	106.0	COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,1RY5B@1236|Gammaproteobacteria,2PZMN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
k59_919092_1	1123518.ARWI01000001_gene757	1.73e-56	183.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,460FK@72273|Thiotrichales	72273|Thiotrichales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_919092_2	1123514.KB905899_gene1556	1.71e-160	454.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,460GA@72273|Thiotrichales	72273|Thiotrichales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_919092_3	1123518.ARWI01000001_gene759	4.08e-68	213.0	2FG19@1|root,347Y0@2|Bacteria,1P155@1224|Proteobacteria,1SS4D@1236|Gammaproteobacteria,462VN@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_637590_1	1380600.AUYN01000001_gene2478	1.15e-129	371.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia	976|Bacteroidetes	S	Phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_637590_2	1178825.ALIH01000002_gene1041	0.000128	42.4	COG4818@1|root,COG4818@2|Bacteria,4NUVP@976|Bacteroidetes,1I44F@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_411351_1	945713.IALB_2927	1.42e-14	79.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,CBM_6,DUF1565,PDZ_2,Trypsin_2
k59_1767459_1	1121931.AUHG01000011_gene1647	1.66e-110	325.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1HX81@117743|Flavobacteriia	976|Bacteroidetes	I	synthase	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1767459_2	1121897.AUGO01000003_gene1737	5.45e-07	50.8	28NFT@1|root,2ZBI1@2|Bacteria,4NJ8P@976|Bacteroidetes,1I11A@117743|Flavobacteriia,2NXXQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_411354_1	1123518.ARWI01000001_gene2207	2.6e-118	363.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,461XY@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1370507_2	1392488.JHZY01000004_gene1693	2.01e-33	117.0	2EVE1@1|root,33NUE@2|Bacteria,4NYCD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_863009_1	85643.Tmz1t_3800	1.61e-77	246.0	COG0438@1|root,COG0438@2|Bacteria,1RGJZ@1224|Proteobacteria,2W2WQ@28216|Betaproteobacteria,2KYX8@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
k59_863009_2	1123517.JOMR01000001_gene1317	1.31e-140	405.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	wecB	-	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_807072_1	1123518.ARWI01000001_gene1208	3.15e-100	297.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales	72273|Thiotrichales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_863011_1	1123518.ARWI01000001_gene135	6.86e-41	145.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,45ZPT@72273|Thiotrichales	72273|Thiotrichales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_863011_2	1123518.ARWI01000001_gene136	1.03e-90	271.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,460SE@72273|Thiotrichales	72273|Thiotrichales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_1197564_1	471223.GWCH70_1970	2.07e-19	89.4	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4HB5P@91061|Bacilli,1WE83@129337|Geobacillus	91061|Bacilli	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1197564_3	1178825.ALIH01000009_gene1371	3.17e-111	335.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1HYRD@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_1427607_1	411154.GFO_1966	2.19e-106	322.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_637652_1	572480.Arnit_2910	8.37e-104	304.0	COG0745@1|root,COG0745@2|Bacteria,1Q49B@1224|Proteobacteria,431SE@68525|delta/epsilon subdivisions,2YSE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_637652_2	572480.Arnit_2909	4.99e-33	123.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2YP1Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
k59_751431_4	317025.Tcr_1920	1.47e-23	99.8	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG2202@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZ2Z@1236|Gammaproteobacteria,461N6@72273|Thiotrichales	72273|Thiotrichales	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_9,SBP_bac_3
k59_74745_1	1380600.AUYN01000001_gene2687	2.58e-228	634.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1429316_1	1227454.C446_03841	9.58e-37	151.0	COG0643@1|root,arCOG03730@1|root,arCOG03730@2157|Archaea,arCOG04403@2157|Archaea,2XSUS@28890|Euryarchaeota,23T9R@183963|Halobacteria	183963|Halobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k59_413150_1	90814.KL370891_gene1608	5.46e-58	196.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1S2RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1089779_1	1353276.JADR01000008_gene869	1.6e-131	385.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1656129_1	1237149.C900_04428	1.35e-32	115.0	COG1695@1|root,COG1695@2|Bacteria,4P48E@976|Bacteroidetes,47V9J@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
k59_1656129_2	1237149.C900_04427	1.19e-43	159.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47UBY@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1259916_1	1237149.C900_02535	1.06e-53	185.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1034344_1	572480.Arnit_0657	8.51e-94	296.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1429339_1	563040.Saut_0741	1.22e-78	248.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_1429339_2	572480.Arnit_1226	2.81e-30	116.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2YNPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Abc transporter, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1712617_1	1380600.AUYN01000009_gene1701	5.09e-132	378.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_1712617_2	1197477.IA57_08950	1.29e-08	53.1	2EN44@1|root,33FS7@2|Bacteria,4NY0X@976|Bacteroidetes,1I5NI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1259933_1	748247.AZKH_1501	1.85e-139	414.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KVAY@206389|Rhodocyclales	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_751471_1	1208321.D104_07350	3.57e-69	213.0	COG0698@1|root,COG0698@2|Bacteria,1MWIB@1224|Proteobacteria,1RPEG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	isomerase	Z012_03465	-	5.3.1.26,5.3.1.6	ko:K01808,ko:K01819	ko00030,ko00051,ko00052,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R03240,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3666,LacAB_rpiB
k59_1089812_1	1150621.SMUL_0548	7.15e-41	154.0	COG2199@1|root,COG3614@1|root,COG3614@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2YMI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,PAS_9
k59_582630_1	1042156.CXIVA_24490	8.5e-05	44.3	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,36E73@31979|Clostridiaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_582630_2	1313421.JHBV01000015_gene5768	2.22e-70	232.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
k59_751492_1	411154.GFO_3223	1.5e-118	348.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1259959_1	1121887.AUDK01000017_gene47	6.7e-111	328.0	COG1649@1|root,COG1649@2|Bacteria,4NGFW@976|Bacteroidetes,1HYGF@117743|Flavobacteriia,2NV55@237|Flavobacterium	976|Bacteroidetes	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015,GHL10
k59_1656186_1	572480.Arnit_0002	1.4e-122	357.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_751503_1	1172190.M947_10585	4.8e-95	300.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1486626_1	1121912.AUHD01000003_gene3136	5.79e-168	511.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1486626_2	1392498.JQLH01000001_gene1134	1.14e-169	481.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1HY1B@117743|Flavobacteriia,2PG7T@252356|Maribacter	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
k59_1656197_1	945713.IALB_0960	1.74e-15	78.6	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_16810_1	1250278.JQNQ01000001_gene3312	1.07e-65	221.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_864884_1	411154.GFO_1777	3.1e-151	433.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_1712684_1	425104.Ssed_3320	3.61e-24	96.7	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,2QC1W@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF423)	ygdD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF423
k59_1259992_1	929558.SMGD1_2848	7.77e-136	387.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2YNEP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1429405_1	666681.M301_2309	1.46e-31	128.0	COG2203@1|root,COG3447@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KNQY@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_696671_1	411154.GFO_2222	5.46e-161	458.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_696671_2	411154.GFO_2221	3.45e-15	74.3	2A8YX@1|root,338VI@2|Bacteria,4NX0Q@976|Bacteroidetes,1I61T@117743|Flavobacteriia	976|Bacteroidetes	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
k59_1317899_1	1313421.JHBV01000032_gene1585	3.21e-16	73.9	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1ISJH@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1317899_2	504487.JCM19302_2454	2.56e-140	398.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1HX6E@117743|Flavobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
k59_244363_1	1172190.M947_00410	1.47e-186	521.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2YMZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_1199054_1	563040.Saut_2034	8.31e-129	384.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42MBE@68525|delta/epsilon subdivisions,2YNGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1317909_1	318167.Sfri_2901	3.3e-67	219.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,2Q987@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_1808	PGI
k59_355973_1	1123518.ARWI01000001_gene472	8.69e-133	399.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,461YR@72273|Thiotrichales	72273|Thiotrichales	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_470254_1	1121931.AUHG01000010_gene450	1.21e-25	104.0	COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,1I085@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Mannitol dehydrogenase C-terminal domain	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k59_470254_2	1121931.AUHG01000010_gene451	3.33e-54	184.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1HXWR@117743|Flavobacteriia	976|Bacteroidetes	G	Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k59_1034461_2	926559.JoomaDRAFT_3514	2.44e-29	115.0	COG2885@1|root,COG2885@2|Bacteria,4NQKV@976|Bacteroidetes,1I3QA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1209954_1	411154.GFO_3566	6.42e-34	125.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1209954_2	1121931.AUHG01000010_gene596	1e-167	471.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1HWP6@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_1335249_2	411154.GFO_3382	7.75e-45	145.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1I3VI@117743|Flavobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_989612_1	572480.Arnit_1621	3.09e-37	132.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04305	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_989612_2	572480.Arnit_1620	3.5e-91	269.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2YNVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_881442_1	273121.WS0144	2.82e-22	100.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
k59_1503877_1	944547.ABLL_1214	8.68e-05	42.7	COG1476@1|root,COG1476@2|Bacteria,1QV0H@1224|Proteobacteria,42UQ2@68525|delta/epsilon subdivisions,2YPUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_714950_1	1123234.AUKI01000015_gene2286	6.58e-18	82.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_714950_2	411154.GFO_0537	1.28e-130	377.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1HX2G@117743|Flavobacteriia	976|Bacteroidetes	S	O-Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
k59_1388879_2	641526.ADIWIN_1384	0.000774	45.8	COG0545@1|root,COG0545@2|Bacteria,4NNK2@976|Bacteroidetes,1I2FD@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1729154_1	946483.Cenrod_2633	1.39e-19	94.4	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
k59_1729154_2	1123518.ARWI01000001_gene1672	5.29e-28	111.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_429904_2	572480.Arnit_2741	1.54e-96	285.0	COG3663@1|root,COG3663@2|Bacteria	2|Bacteria	L	G/U mismatch-specific uracil-DNA glycosylase activity	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
k59_542354_1	290397.Adeh_3017	6.08e-15	70.9	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_542354_2	944480.ATUV01000002_gene466	4.5e-17	80.5	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2M6NY@213113|Desulfurellales	28221|Deltaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_936392_1	1123518.ARWI01000001_gene308	2.51e-49	173.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,46047@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_936392_2	1123514.KB905899_gene1324	2.51e-56	182.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,46099@72273|Thiotrichales	72273|Thiotrichales	C	Succinate dehydrogenase fumarate reductase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
k59_372314_1	1178825.ALIH01000002_gene1050	2.1e-82	259.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_714972_1	1492738.FEM21_29180	4.92e-26	105.0	COG0463@1|root,COG0463@2|Bacteria,4NKPW@976|Bacteroidetes,1HXNR@117743|Flavobacteriia,2P092@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1503917_1	1123367.C666_07830	1.28e-70	224.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,2KW21@206389|Rhodocyclales	206389|Rhodocyclales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_1729174_1	504487.JCM19302_2400	1.81e-160	455.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1HWWG@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_1729174_2	1443665.JACA01000020_gene4906	2.58e-56	184.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HYY3@117743|Flavobacteriia,2YIDH@290174|Aquimarina	976|Bacteroidetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_319545_1	1380600.AUYN01000003_gene120	1.82e-67	211.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k59_206667_1	1123517.JOMR01000001_gene1388	1.64e-05	45.8	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,46020@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_206667_2	1168067.JAGP01000001_gene1594	1.2e-07	54.3	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,460Z9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_319553_1	865937.Gilli_2339	3e-07	50.8	COG2354@1|root,COG2354@2|Bacteria,4NG5M@976|Bacteroidetes,1HXU9@117743|Flavobacteriia,2P667@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_1211862_1	1150621.SMUL_0616	4.29e-38	138.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42QH4@68525|delta/epsilon subdivisions,2YNGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_1211862_2	1565314.OA34_03545	4.14e-12	65.1	29BJD@1|root,2ZYHR@2|Bacteria,1Q9EC@1224|Proteobacteria,42SGC@68525|delta/epsilon subdivisions,2YPYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized lipoprotein	-	-	-	ko:K07286	-	-	-	-	ko00000	-	-	-	Lipoprotein_16
k59_1619926_1	395494.Galf_1131	8.73e-87	290.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WBU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_4,PAS_9
k59_206708_1	1122201.AUAZ01000029_gene321	1.14e-77	234.0	COG2193@1|root,COG2193@2|Bacteria,1RD4Y@1224|Proteobacteria,1S40G@1236|Gammaproteobacteria,466D7@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfrA	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_148986_1	1191523.MROS_2455	3.32e-41	136.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_148986_2	391735.Veis_0313	5.41e-07	50.4	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VMTP@28216|Betaproteobacteria,4ABF8@80864|Comamonadaceae	1224|Proteobacteria	IQ	Short-chain dehydrogenase reductase sdr	MA20_01425	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1560643_2	929558.SMGD1_1964	2.08e-51	173.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2YQJT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_263556_1	1123326.JFBL01000001_gene1463	4.81e-18	80.1	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_263556_2	563040.Saut_1772	4.97e-71	221.0	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1391306_1	1137281.D778_00889	1.09e-95	291.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1560675_1	1122194.AUHU01000008_gene3378	7.69e-66	222.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,464Q3@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_991992_2	391603.FBALC1_15127	2.87e-14	71.2	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_938289_1	90813.JQMT01000001_gene1132	3.28e-40	145.0	2F49S@1|root,33X0E@2|Bacteria,1NW6Z@1224|Proteobacteria,1SPQT@1236|Gammaproteobacteria,462HK@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_938289_2	1123518.ARWI01000001_gene2365	9.56e-125	357.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,460AM@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	Intein_splicing,dUTPase
k59_1211935_1	411154.GFO_0285	3.4e-111	329.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,1HXXC@117743|Flavobacteriia	976|Bacteroidetes	S	sulfatase	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
k59_938306_1	563040.Saut_1929	8.4e-114	334.0	2A4YW@1|root,30TKN@2|Bacteria,1PDH4@1224|Proteobacteria,42SHS@68525|delta/epsilon subdivisions,2YPG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1165850_1	395494.Galf_1315	2.04e-09	67.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGMB@28216|Betaproteobacteria,44WAV@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
k59_1279079_1	1565129.JSFF01000019_gene1616	7.98e-148	423.0	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,1SD5U@1236|Gammaproteobacteria,2QA5D@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
k59_1391385_1	1565129.JSFF01000019_gene1661	3.43e-63	199.0	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,2QBGA@267890|Shewanellaceae	1236|Gammaproteobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	sigY	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_35114_1	313603.FB2170_03990	4.37e-155	449.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HYW2@117743|Flavobacteriia,2PHTV@252356|Maribacter	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_93904_1	1355374.JARU01000005_gene1838	2.63e-13	76.3	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2YRDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Putative exonuclease SbcCD, C subunit	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_1391411_1	1123228.AUIH01000002_gene1540	1.8e-75	237.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XHZM@135619|Oceanospirillales	135619|Oceanospirillales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1391411_2	1415780.JPOG01000001_gene538	0.000797	40.8	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1X3JZ@135614|Xanthomonadales	135614|Xanthomonadales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_35136_1	1165841.SULAR_00900	2.57e-76	239.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42QN4@68525|delta/epsilon subdivisions,2YTQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_883995_1	742766.HMPREF9455_01197	1.81e-08	53.9	COG5017@1|root,COG5017@2|Bacteria,4NT46@976|Bacteroidetes,2FVPA@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_883995_2	1167006.UWK_03381	5.65e-36	128.0	COG0707@1|root,COG0707@2|Bacteria,1RJH9@1224|Proteobacteria,432J5@68525|delta/epsilon subdivisions,2WYGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Oligosaccharide biosynthesis protein Alg14 like	-	-	-	-	-	-	-	-	-	-	-	-	Alg14
k59_883995_3	226186.BT_0608	5.36e-43	154.0	COG0438@1|root,COG0438@2|Bacteria,4NVTH@976|Bacteroidetes,2FN27@200643|Bacteroidia,4ASWJ@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1560773_1	1380600.AUYN01000006_gene691	6.37e-78	235.0	COG0517@1|root,COG0517@2|Bacteria,4NNFS@976|Bacteroidetes,1IJF1@117743|Flavobacteriia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1560773_2	1178825.ALIH01000003_gene2080	3.44e-72	217.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
k59_1560773_3	324602.Caur_1277	9.07e-09	57.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_1165890_1	1278078.G419_00940	3.65e-30	112.0	COG2218@1|root,COG2218@2|Bacteria,2I686@201174|Actinobacteria,4FWUD@85025|Nocardiaceae	201174|Actinobacteria	C	GXGXG motif	-	-	2.1.1.21	ko:K22082	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG
k59_1165890_2	317025.Tcr_1344	4.15e-296	810.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,4606M@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase,Rieske
k59_1560785_1	411154.GFO_3142	6.97e-114	332.0	COG0596@1|root,COG0596@2|Bacteria,4PKUD@976|Bacteroidetes,1IJFD@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_1052217_1	1172190.M947_09545	1.62e-19	82.4	2BR51@1|root,32K31@2|Bacteria,1Q8HX@1224|Proteobacteria,433KM@68525|delta/epsilon subdivisions,2YSI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1052217_2	563040.Saut_0665	1.23e-58	191.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1165905_1	411154.GFO_2531	5.81e-114	350.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia	976|Bacteroidetes	E	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_1109040_1	742767.HMPREF9456_00219	4.27e-09	61.6	2EB10@1|root,3351W@2|Bacteria,4NV9Q@976|Bacteroidetes,2FUVX@200643|Bacteroidia,230QS@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_717538_1	411154.GFO_3159	1.83e-191	563.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1447900_1	983545.Glaag_1958	1.57e-49	163.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,466Z7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	membrane	HA62_23750	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k59_770334_1	85643.Tmz1t_1674	1.01e-05	46.2	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VJQ0@28216|Betaproteobacteria,2KUCD@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_770334_2	748247.AZKH_2072	4.97e-90	265.0	2EE9F@1|root,3383V@2|Bacteria,1NBCJ@1224|Proteobacteria,2VW04@28216|Betaproteobacteria,2KYNR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_717541_1	1121931.AUHG01000010_gene769	3.48e-85	262.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_717541_2	411154.GFO_0111	2.36e-13	69.7	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
k59_1052233_1	323848.Nmul_A0618	3.41e-42	155.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,372VN@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1052233_2	1492737.FEM08_02040	1.01e-20	85.5	COG2010@1|root,COG2010@2|Bacteria,4PGR7@976|Bacteroidetes,1IETT@117743|Flavobacteriia,2NY1M@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1391457_1	396588.Tgr7_1851	9.29e-56	196.0	COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXCR@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GGDEF,PAS_3,PAS_4,PAS_9
k59_1109062_1	1123248.KB893348_gene95	3.84e-125	365.0	COG0562@1|root,COG0562@2|Bacteria,4NGXU@976|Bacteroidetes,1IPGJ@117747|Sphingobacteriia	976|Bacteroidetes	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
k59_1731715_1	945713.IALB_2307	1.05e-74	232.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2,Peptidase_C70,TPR_16,TPR_19,TPR_2,TPR_8
k59_770360_2	1347342.BN863_28180	9.23e-139	403.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_600303_1	1197477.IA57_02085	1.54e-156	450.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HYJX@117743|Flavobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_263708_1	1121931.AUHG01000019_gene2968	3.99e-11	64.3	COG3391@1|root,COG3391@2|Bacteria,4NGBX@976|Bacteroidetes,1HXDU@117743|Flavobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_263708_2	411154.GFO_3019	1.81e-56	182.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,1HWXM@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_263710_1	1121921.KB898706_gene2336	5.32e-50	173.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin,T2SS-T3SS_pil_N
k59_829261_2	929558.SMGD1_1855	1.41e-133	388.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_396999_1	929558.SMGD1_1521	7.53e-65	221.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_566357_1	1392490.JHZX01000001_gene1742	1.65e-189	555.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HZFE@117743|Flavobacteriia	976|Bacteroidetes	T	7TMR-DISM extracellular 2	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
k59_566357_2	1443665.JACA01000001_gene3002	5.37e-69	218.0	COG1073@1|root,COG1073@2|Bacteria,4NH47@976|Bacteroidetes,1HYN1@117743|Flavobacteriia,2YH0Q@290174|Aquimarina	976|Bacteroidetes	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9
k59_116118_1	929558.SMGD1_0810	2.17e-84	280.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_681199_1	1123037.AUDE01000044_gene835	6.97e-86	278.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
k59_1754346_1	1123518.ARWI01000001_gene189	2.25e-21	91.3	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,45ZR3@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1754346_2	1123514.KB905899_gene993	1.08e-211	605.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,460FW@72273|Thiotrichales	72273|Thiotrichales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_229250_1	572480.Arnit_0418	9.58e-87	270.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1641544_1	555500.I215_05752	1.34e-12	67.4	COG1773@1|root,COG1773@2|Bacteria,4NHF0@976|Bacteroidetes,1HZ40@117743|Flavobacteriia	976|Bacteroidetes	C	Pfam Rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_624589_1	1537917.JU82_04990	5.92e-157	451.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2YNPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_1189086_1	1178825.ALIH01000005_gene166	1.55e-36	129.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1HY3J@117743|Flavobacteriia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
k59_1189086_2	1347342.BN863_12440	6.04e-32	117.0	COG1443@1|root,COG1443@2|Bacteria,4NRS2@976|Bacteroidetes,1I2UY@117743|Flavobacteriia	976|Bacteroidetes	I	Hydrolase of MutT (Nudix) family protein	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_907020_1	391587.KAOT1_21866	1.17e-17	88.6	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
k59_1415316_1	768671.ThimaDRAFT_3694	7.8e-43	148.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1WWC0@135613|Chromatiales	135613|Chromatiales	T	PFAM HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_285643_1	945543.VIBR0546_16823	1.14e-44	164.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1Y2H6@135623|Vibrionales	135623|Vibrionales	M	COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
k59_285643_2	1123518.ARWI01000001_gene973	1.49e-95	286.0	COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,1S3TT@1236|Gammaproteobacteria,460NA@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
k59_285643_3	1123517.JOMR01000001_gene1797	4.38e-35	129.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,4609M@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1245310_1	1137281.D778_00893	5.08e-190	534.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1HWPX@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_1245310_2	1178825.ALIH01000002_gene1074	2.45e-100	293.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,1I27H@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
k59_1245310_3	504487.JCM19302_1153	8.01e-51	169.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_1132865_1	1137281.D778_00439	0.0	873.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_1132865_3	1267211.KI669560_gene822	2.25e-87	263.0	29G3D@1|root,30315@2|Bacteria,4NP6X@976|Bacteroidetes,1IUDK@117747|Sphingobacteriia	976|Bacteroidetes	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
k59_1132865_4	1267211.KI669560_gene821	1.04e-183	523.0	COG1106@1|root,COG1106@2|Bacteria,4NE5J@976|Bacteroidetes,1IQEZ@117747|Sphingobacteriia	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k59_1528155_1	1121931.AUHG01000019_gene2989	1.47e-99	292.0	2CPY4@1|root,32SK3@2|Bacteria,4NTVY@976|Bacteroidetes,1I490@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
k59_1528164_1	1123518.ARWI01000001_gene831	2.01e-133	397.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
k59_1584963_1	1123514.KB905899_gene1779	3.19e-13	66.6	COG1522@1|root,COG1522@2|Bacteria,1RG35@1224|Proteobacteria,1S484@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_341646_1	563040.Saut_0117	9.56e-105	320.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1302692_1	1380600.AUYN01000009_gene1317	1.33e-228	630.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1HXN1@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_1302692_2	1380600.AUYN01000009_gene1319	7.16e-43	144.0	2DM2K@1|root,31G7J@2|Bacteria,4NQIU@976|Bacteroidetes,1I2UQ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_1132881_1	504487.JCM19302_3067	2.15e-40	140.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k59_1132881_2	983544.Lacal_2234	2.8e-65	211.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HZ6Y@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1415337_1	1178825.ALIH01000008_gene766	1.07e-155	487.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HYR,Laminin_G_3,SprB
k59_1697801_1	1380600.AUYN01000009_gene2015	4.56e-05	43.9	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,1I2TK@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
k59_1697801_2	1139219.I569_02706	3.18e-27	107.0	COG0454@1|root,COG0456@2|Bacteria,1V4Y1@1239|Firmicutes,4HHH1@91061|Bacilli,4B2F2@81852|Enterococcaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_1697801_3	1380600.AUYN01000009_gene2013	3.64e-114	331.0	COG1272@1|root,COG1272@2|Bacteria,4NM95@976|Bacteroidetes,1HYZQ@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein, hemolysin III homolog	hly-III	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k59_1020168_1	504487.JCM19302_4237	3.97e-148	424.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
k59_624640_1	1123053.AUDG01000005_gene3901	9.13e-12	68.9	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1WXF1@135613|Chromatiales	135613|Chromatiales	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_624640_2	95619.PM1_0209860	7.01e-37	132.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
k59_172892_1	1123392.AQWL01000011_gene2247	1.04e-96	308.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KR9P@119069|Hydrogenophilales	119069|Hydrogenophilales	V	AcrB/AcrD/AcrF family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_455338_1	1469557.JSWF01000017_gene2316	6.99e-71	222.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,1HXI9@117743|Flavobacteriia	976|Bacteroidetes	S	Dehydrogenase	-	-	1.1.1.1	ko:K12957,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_567942_1	1178825.ALIH01000002_gene1091	1.56e-91	271.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
k59_567942_2	504487.JCM19302_1202	2.37e-221	616.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1HWNU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_681294_1	866536.Belba_3130	4.89e-69	231.0	COG1002@1|root,COG1002@2|Bacteria,4NFKA@976|Bacteroidetes,47KR1@768503|Cytophagia	976|Bacteroidetes	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
k59_624651_2	1355368.JART01000017_gene2015	7.4e-29	105.0	COG3937@1|root,COG3937@2|Bacteria,1P8D3@1224|Proteobacteria,42VTS@68525|delta/epsilon subdivisions,2YQ89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_624651_3	398767.Glov_1388	4.18e-20	90.1	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_285708_1	572480.Arnit_1737	3.43e-128	382.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1302732_1	765914.ThisiDRAFT_1399	3.78e-105	318.0	COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales	135613|Chromatiales	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_1641624_1	1380600.AUYN01000009_gene1124	6.47e-277	787.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1302751_1	1121931.AUHG01000019_gene3017	5.06e-188	537.0	COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia	976|Bacteroidetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
k59_172929_1	572480.Arnit_2519	4.7e-21	91.7	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_172929_2	1249480.B649_06345	4.51e-35	120.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2YQBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Redox-active disulfide protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_172929_3	572480.Arnit_2523	3.3e-05	43.9	COG2105@1|root,COG2105@2|Bacteria,1N814@1224|Proteobacteria,430QM@68525|delta/epsilon subdivisions,2YS0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
k59_285728_1	631362.Thi970DRAFT_02485	1.51e-51	184.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,1RYBW@1236|Gammaproteobacteria,1X0HK@135613|Chromatiales	135613|Chromatiales	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_59856_1	1123518.ARWI01000001_gene430	2.77e-37	127.0	COG0526@1|root,COG0526@2|Bacteria,1N9U2@1224|Proteobacteria,1SG9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_59856_2	90814.KL370891_gene1883	1.11e-60	194.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_59856_3	317025.Tcr_0935	5.03e-22	93.2	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,460RS@72273|Thiotrichales	72273|Thiotrichales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_1415388_1	746697.Aeqsu_2951	3.39e-42	149.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucosamine mutase	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1415388_2	1380600.AUYN01000001_gene2363	6.2e-111	322.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
k59_1415388_3	1137281.D778_00871	2.18e-18	85.5	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia	976|Bacteroidetes	E	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_907095_1	1250278.JQNQ01000001_gene1912	2.05e-102	327.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
k59_341685_1	323261.Noc_0789	1.26e-18	84.3	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_341685_2	90814.KL370891_gene1129	1.7e-51	170.0	COG2840@1|root,COG2840@2|Bacteria	2|Bacteria	U	Smr protein MutS2	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_341685_3	1123517.JOMR01000001_gene1028	1.08e-23	94.7	COG2919@1|root,COG2919@2|Bacteria,1QSKU@1224|Proteobacteria,1RW3G@1236|Gammaproteobacteria,463B1@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k59_341685_4	1168067.JAGP01000001_gene1088	2.59e-278	764.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_341685_5	1123514.KB905899_gene952	4.98e-99	293.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales	72273|Thiotrichales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_1358391_1	935557.ATYB01000008_gene4688	2.85e-28	112.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2TR9B@28211|Alphaproteobacteria,4B7HW@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	gguB	GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0019321,GO:0031224,GO:0042732,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
k59_1358391_2	595537.Varpa_1115	8.86e-71	229.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VHRA@28216|Betaproteobacteria,4A9T3@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC transporter	gguA	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
k59_3366_1	1123518.ARWI01000001_gene638	1.62e-127	371.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,4609R@72273|Thiotrichales	72273|Thiotrichales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_3366_2	317025.Tcr_1468	7.63e-41	140.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,4612A@72273|Thiotrichales	72273|Thiotrichales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_455394_1	317025.Tcr_1543	2.58e-16	77.8	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,45ZXU@72273|Thiotrichales	72273|Thiotrichales	NT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
k59_455394_2	1123517.JOMR01000001_gene1845	4.32e-109	320.0	28M4C@1|root,2ZAIA@2|Bacteria,1R67D@1224|Proteobacteria,1RQQQ@1236|Gammaproteobacteria,460BT@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_398814_1	1191523.MROS_1980	1.09e-28	117.0	COG0260@1|root,COG0260@2|Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_1754492_1	869213.JCM21142_31268	6.7e-36	122.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,47RFD@768503|Cytophagia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_1754492_2	1347342.BN863_5820	5.24e-224	625.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_794193_2	1226994.AMZB01000137_gene5411	1.83e-29	110.0	2EIQ2@1|root,33CFI@2|Bacteria,1NHAI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1302795_1	929558.SMGD1_1559	3.79e-86	258.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2YMQX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1302795_2	563040.Saut_1914	8.44e-29	114.0	COG1426@1|root,COG1426@2|Bacteria,1Q33C@1224|Proteobacteria,42WQB@68525|delta/epsilon subdivisions,2YQFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1754495_1	460265.Mnod_5946	7.25e-47	162.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,1JTRM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	TIGRFAM TRAP transporter, DctM subunit	dctM	GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM,DctQ
k59_1754495_2	1121127.JAFA01000006_gene5473	2.13e-40	142.0	COG0583@1|root,COG0583@2|Bacteria,1R9N4@1224|Proteobacteria,2VRR6@28216|Betaproteobacteria,1KGGC@119060|Burkholderiaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_285769_1	1250278.JQNQ01000001_gene671	4.13e-33	128.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,1HY7X@117743|Flavobacteriia	976|Bacteroidetes	U	Carboxypeptidase regulatory-like domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
k59_285769_2	1121931.AUHG01000015_gene1193	3.92e-26	104.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_116262_1	1123228.AUIH01000003_gene976	1.79e-44	164.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XR36@135619|Oceanospirillales	135619|Oceanospirillales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
k59_1302805_1	555500.I215_05897	1.13e-24	102.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_849971_1	1499680.CCFE01000021_gene1906	9.14e-20	94.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,4HCJG@91061|Bacilli,1ZDES@1386|Bacillus	91061|Bacilli	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_455442_1	1178825.ALIH01000002_gene1039	1.2e-157	467.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1HYC9@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
k59_1086672_2	1121434.AULY01000007_gene1291	1.37e-11	63.9	COG2207@1|root,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,43ARB@68525|delta/epsilon subdivisions,2X69Z@28221|Deltaproteobacteria,2MH0G@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_409953_1	1347342.BN863_23420	2.49e-97	308.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_409953_2	1380600.AUYN01000009_gene2058	2.81e-196	556.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1HX8F@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
k59_409953_3	1347342.BN863_9120	5.15e-148	420.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
k59_409953_4	1380600.AUYN01000009_gene2060	4.97e-160	456.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1314479_1	572480.Arnit_3034	2.23e-154	459.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YRFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_296975_1	1178825.ALIH01000015_gene1880	1.13e-66	206.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1I185@117743|Flavobacteriia	976|Bacteroidetes	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_296975_2	1380600.AUYN01000001_gene2327	3.58e-40	141.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,1I24J@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
k59_1256676_1	448385.sce6908	2.27e-16	82.8	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,42M3Z@68525|delta/epsilon subdivisions,2WJIR@28221|Deltaproteobacteria,2YWFB@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k59_636213_1	637905.SVI_2052	5.89e-97	302.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,2Q9Y1@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ1	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_13752_2	945713.IALB_2375	9.01e-54	174.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
k59_409962_1	416870.llmg_1100	4.91e-67	208.0	COG1187@1|root,COG1187@2|Bacteria,1VV8P@1239|Firmicutes,4HVHJ@91061|Bacilli,1YBZW@1357|Lactococcus	91061|Bacilli	G	RNA pseudouridylate synthase	rluC	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1596759_1	398579.Spea_3524	5.18e-217	608.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,2QD7K@267890|Shewanellaceae	1236|Gammaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1369089_1	1178825.ALIH01000001_gene2502	1.34e-59	192.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1HXDH@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1369089_2	983544.Lacal_0658	1.2e-43	151.0	COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,1HX57@117743|Flavobacteriia	976|Bacteroidetes	H	Prenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1652904_1	1137281.D778_01915	5.15e-07	49.3	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1I2XD@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
k59_1652904_2	1137281.D778_01916	1.41e-83	268.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_184573_1	745718.JADT01000015_gene2896	4.12e-48	159.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HXRV@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_184573_2	1121912.AUHD01000001_gene2355	3.02e-101	299.0	28NPC@1|root,2ZBPA@2|Bacteria,4NMF8@976|Bacteroidetes,1I1A0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_805625_6	1112217.PPL19_22419	9.29e-32	120.0	COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,1S2SY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	5'-deoxynucleotidase activity	yfdR	GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897	-	ko:K06952	-	-	-	-	ko00000	-	-	-	-
k59_861579_1	1123518.ARWI01000001_gene1211	5.28e-108	323.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_861579_2	1123514.KB905899_gene1963	2.62e-109	317.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,45ZPZ@72273|Thiotrichales	72273|Thiotrichales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
k59_409996_1	1454007.JAUG01000011_gene2329	6.51e-103	303.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1INQS@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_71462_1	1178825.ALIH01000006_gene1445	3.57e-78	258.0	COG0308@1|root,COG0308@2|Bacteria,4NEJR@976|Bacteroidetes,1HYMW@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1314528_1	317025.Tcr_1371	5.79e-41	142.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,460GM@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_861588_1	1168065.DOK_09284	9.67e-06	46.6	COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1J5PN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	cmpR_1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_861588_2	1298593.TOL_1528	1.72e-80	251.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XIQG@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_466905_1	1123514.KB905899_gene1893	6.74e-37	129.0	2FIFI@1|root,34A7R@2|Bacteria,1P365@1224|Proteobacteria,1SS4R@1236|Gammaproteobacteria,4631F@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_466905_2	90814.KL370891_gene147	8.01e-31	116.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1S8CZ@1236|Gammaproteobacteria,46317@72273|Thiotrichales	72273|Thiotrichales	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
k59_1709420_1	1168067.JAGP01000001_gene736	5.98e-18	82.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,4631P@72273|Thiotrichales	72273|Thiotrichales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	-	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k59_1709420_2	1168067.JAGP01000001_gene735	8.35e-82	243.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,460U7@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1709420_3	1123514.KB905899_gene1417	4.92e-52	171.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,460EM@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_917852_1	746697.Aeqsu_2123	4.98e-122	367.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1766110_1	1123518.ARWI01000001_gene2431	1.38e-101	301.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,461RE@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_1766110_2	90814.KL370891_gene1295	1.23e-155	452.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1369144_1	90814.KL370891_gene384	5.83e-15	74.3	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,460JU@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
k59_1369144_2	1123518.ARWI01000001_gene891	1.7e-131	382.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,45ZNA@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_13800_2	1380600.AUYN01000012_gene2964	1.58e-235	656.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1HWNP@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
k59_13800_3	504487.JCM19302_2442	2.28e-53	187.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k59_71480_1	1178825.ALIH01000007_gene1680	1.43e-108	322.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1HXQB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_71480_2	504487.JCM19302_503	9.84e-34	122.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1HX1Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_297063_1	749222.Nitsa_1267	2.93e-18	83.6	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2YMG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0026	Citrate_synt
k59_297063_2	944547.ABLL_1946	7.14e-73	226.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,42URC@68525|delta/epsilon subdivisions,2YPX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_917884_2	439235.Dalk_3120	9.42e-40	148.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,42MRG@68525|delta/epsilon subdivisions,2WJ5Q@28221|Deltaproteobacteria,2MINB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase M16C associated	PREP	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_693308_1	1178825.ALIH01000018_gene1178	1.43e-230	637.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX09@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_693308_2	1347342.BN863_14160	2.58e-261	732.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_1596849_1	700598.Niako_6709	1.37e-11	68.2	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IPMN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_1652978_1	1380600.AUYN01000006_gene411	3.11e-25	98.2	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I28Y@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
k59_1652978_2	1380600.AUYN01000006_gene410	7.89e-207	578.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes,1HY6U@117743|Flavobacteriia	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1596867_1	1484460.JSWG01000012_gene1423	2.86e-88	271.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1HYZG@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1596867_2	1121912.AUHD01000001_gene2385	1.01e-88	262.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1I19I@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
k59_1596867_3	1392490.JHZX01000001_gene1007	2.11e-69	214.0	COG4083@1|root,COG4083@2|Bacteria,4NM52@976|Bacteroidetes,1I1BK@117743|Flavobacteriia	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
k59_1766167_1	439292.Bsel_3197	2.71e-13	74.7	COG1132@1|root,COG1132@2|Bacteria,1TUQD@1239|Firmicutes,4HTPJ@91061|Bacilli	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,cNMP_binding
k59_410076_1	1172190.M947_00145	1.62e-96	286.0	COG1136@1|root,COG1136@2|Bacteria,1PFRW@1224|Proteobacteria,42P38@68525|delta/epsilon subdivisions,2YT0X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_972529_1	1137281.D778_00306	0.0	897.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_972529_3	1137281.D778_00304	2.1e-183	515.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1HYAP@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1031364_1	634956.Geoth_3128	9.51e-71	248.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1WE8N@129337|Geobacillus	91061|Bacilli	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS,PAS_4,PAS_9,dCache_1
k59_1483422_1	85643.Tmz1t_0805	2.88e-106	329.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,2KV4W@206389|Rhodocyclales	206389|Rhodocyclales	I	AcyL-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_184677_1	929558.SMGD1_0934	5.73e-117	347.0	COG0667@1|root,COG0667@2|Bacteria,1RHYD@1224|Proteobacteria,42SEU@68525|delta/epsilon subdivisions,2YT8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_522787_1	411154.GFO_0253	9.28e-105	320.0	COG1132@1|root,COG1132@2|Bacteria,4NHI1@976|Bacteroidetes,1HX07@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_241095_1	411154.GFO_1902	2.8e-80	247.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1HWZT@117743|Flavobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_1766197_1	1348657.M622_15005	6.22e-114	353.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,2KUZT@206389|Rhodocyclales	206389|Rhodocyclales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_1196599_1	399739.Pmen_2791	3.31e-40	142.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1YF0X@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479	ABC_tran
k59_1709536_1	1121931.AUHG01000011_gene1660	5.6e-67	229.0	COG4886@1|root,COG4932@1|root,COG4935@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_467012_1	1168067.JAGP01000001_gene1695	1.93e-29	117.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,46089@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_467012_2	317025.Tcr_0498	1.66e-195	553.0	COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4605G@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM lytic murein transglycosylase	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	PG_binding_1,SLT_2
k59_467012_4	90814.KL370891_gene1025	7.95e-139	411.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,4608M@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1426393_1	1380600.AUYN01000001_gene2223	1.69e-141	404.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1HWV1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
k59_805770_1	323850.Shew_0765	1.08e-85	278.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q8ZE@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1426395_1	1121912.AUHD01000004_gene2029	2.97e-64	207.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1HZDU@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_1426395_2	504487.JCM19302_1671	3.09e-163	474.0	COG2273@1|root,COG2273@2|Bacteria,4NHWA@976|Bacteroidetes,1HX44@117743|Flavobacteriia	976|Bacteroidetes	G	Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1256865_1	90814.KL370892_gene2172	2.36e-76	242.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,45ZS7@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM general secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1256865_2	765914.ThisiDRAFT_1295	4.34e-56	190.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_410159_1	1296415.JACC01000106_gene3756	5.43e-247	681.0	COG2801@1|root,COG2801@2|Bacteria,4NWHG@976|Bacteroidetes,1IMJP@117743|Flavobacteriia	976|Bacteroidetes	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve_3
k59_1086880_1	400668.Mmwyl1_0108	7.41e-72	244.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1XIFC@135619|Oceanospirillales	135619|Oceanospirillales	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_1653080_1	1123518.ARWI01000001_gene1761	4.13e-69	215.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4624T@72273|Thiotrichales	72273|Thiotrichales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_1653080_2	1123518.ARWI01000001_gene1762	9.04e-140	397.0	COG4149@1|root,COG4149@2|Bacteria	2|Bacteria	P	molybdate abc transporter	modB	-	-	ko:K02018,ko:K15496	ko02010,map02010	M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
k59_1653080_3	1123518.ARWI01000001_gene1763	7.24e-62	201.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,461NT@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_242948_1	504487.JCM19302_4119	1.86e-14	71.2	COG2825@1|root,COG2825@2|Bacteria,4NN8F@976|Bacteroidetes,1I21G@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_242948_2	1380600.AUYN01000007_gene3115	1.18e-91	278.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1HXGT@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1540690_1	1232410.KI421418_gene2442	6.16e-101	300.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2X2AF@28221|Deltaproteobacteria,43TXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_1711321_1	90813.JQMT01000001_gene839	5.8e-51	166.0	COG2897@1|root,COG2897@2|Bacteria,1QVX5@1224|Proteobacteria,1T2MK@1236|Gammaproteobacteria,463U6@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1711321_2	1168067.JAGP01000001_gene993	1.67e-45	157.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Lipase_GDSL_2
k59_1033148_1	1380600.AUYN01000001_gene2695	1.81e-116	343.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1HX4E@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1555911_1	1232410.KI421412_gene434	2.74e-58	190.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,42RD8@68525|delta/epsilon subdivisions,2WN8F@28221|Deltaproteobacteria,43TFY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1332908_1	1137281.D778_02124	1.85e-299	841.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1501490_2	929558.SMGD1_2597	1.37e-65	211.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YMD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_712557_1	411154.GFO_2999	1.81e-96	313.0	COG0784@1|root,COG1520@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1520@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NK8Q@976|Bacteroidetes,1IMWE@117743|Flavobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HTH_18,Reg_prop,SpoIIE,Y_Y_Y
k59_1726849_1	1392498.JQLH01000001_gene819	6.78e-137	397.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,1HXB1@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_712561_1	563040.Saut_0916	5.81e-72	238.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1208543_1	1123518.ARWI01000001_gene38	7.21e-26	95.5	COG3530@1|root,COG3530@2|Bacteria	2|Bacteria	L	Putative quorum-sensing-regulated virulence factor	ypeB	-	2.7.7.7	ko:K02342,ko:K09954,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	QSregVF_b
k59_1208543_2	243265.plu4451	4.25e-37	142.0	COG1112@1|root,COG3096@1|root,COG3267@1|root,COG1112@2|Bacteria,COG3096@2|Bacteria,COG3267@2|Bacteria,1MW2R@1224|Proteobacteria,1RS68@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
k59_934450_1	1172190.M947_10255	9.49e-208	601.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_934450_2	563040.Saut_0473	2.98e-63	212.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2YNF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_824304_1	886377.Murru_1046	1.07e-70	218.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
k59_824304_2	1004149.AFOE01000003_gene2188	3.65e-06	45.4	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1I2S0@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_1161014_1	563040.Saut_1516	3.91e-178	501.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2YMA7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_1161014_2	593117.TGAM_2148	1.54e-08	56.6	COG0463@1|root,arCOG01381@2157|Archaea,2XVM0@28890|Euryarchaeota,243JM@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_596263_1	1178825.ALIH01000011_gene48	2.1e-158	453.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_596263_2	1380600.AUYN01000009_gene1367	1.06e-51	168.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
k59_202097_2	1123518.ARWI01000001_gene72	5.32e-68	223.0	COG0428@1|root,COG2905@1|root,COG0428@2|Bacteria,COG2905@2|Bacteria,1QE6Q@1224|Proteobacteria,1S080@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	cNMP_binding
k59_202097_3	998674.ATTE01000001_gene2550	9.32e-103	311.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,4608J@72273|Thiotrichales	72273|Thiotrichales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
k59_314851_1	326298.Suden_0397	2.86e-127	367.0	COG1076@1|root,COG1076@2|Bacteria,1N8QM@1224|Proteobacteria,43B25@68525|delta/epsilon subdivisions,2YT59@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_314851_2	326298.Suden_0400	4.14e-15	73.6	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_314859_1	1026882.MAMP_00452	5.21e-23	93.2	COG1865@1|root,COG1865@2|Bacteria,1RJXU@1224|Proteobacteria,1SBM6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Adenosylcobinamide amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CbiZ
k59_314859_2	572480.Arnit_2003	2.39e-72	224.0	COG1357@1|root,COG1357@2|Bacteria,1REAS@1224|Proteobacteria,42NY4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Pentapeptide repeats (9 copies)	mcbG	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
k59_427634_2	1168289.AJKI01000031_gene915	6.94e-25	98.2	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,2G2VX@200643|Bacteroidia,3XK1H@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_30504_2	1121931.AUHG01000012_gene2875	1.54e-163	489.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_879198_1	945713.IALB_1700	4.6e-66	215.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_765686_1	1123008.KB905694_gene1772	2.54e-84	261.0	COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,2FNHE@200643|Bacteroidia,22WP2@171551|Porphyromonadaceae	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1048270_1	929558.SMGD1_2210	4.5e-84	268.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_1784303_1	411154.GFO_0449	4.19e-47	157.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,1I2S6@117743|Flavobacteriia	976|Bacteroidetes	S	MobA-related protein	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_484662_1	1205683.CAKR01000028_gene3817	2.56e-34	133.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,41DKE@629|Yersinia	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_765704_1	411154.GFO_3463	8.53e-122	375.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_653883_1	1304275.C41B8_07127	1.9e-22	97.4	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	cheA	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt
k59_653883_2	557598.LHK_00561	6.84e-33	117.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,2KREH@206351|Neisseriales	206351|Neisseriales	T	Chemotaxis protein cheY	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_765707_1	90814.KL370891_gene182	1.33e-96	293.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_765707_2	1168067.JAGP01000001_gene1856	7.75e-44	151.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,45ZP5@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_712649_1	572480.Arnit_2355	1.49e-227	630.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_712649_2	572480.Arnit_2354	3.29e-07	51.2	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1274397_1	946483.Cenrod_2399	4.03e-13	76.3	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4AD7J@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_1670637_1	1442598.JABW01000030_gene1381	9.36e-72	224.0	COG2064@1|root,COG2064@2|Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510,ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_484700_1	1123367.C666_15455	1.56e-24	99.8	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,2KVKA@206389|Rhodocyclales	206389|Rhodocyclales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_1386646_1	985255.APHJ01000025_gene1019	2.66e-51	169.0	COG2890@1|root,COG2890@2|Bacteria,4PKK6@976|Bacteroidetes,1IJBI@117743|Flavobacteriia,2P6A9@244698|Gillisia	976|Bacteroidetes	J	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_89105_1	929558.SMGD1_2585	5.74e-67	214.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YP18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_596359_1	1392490.JHZX01000001_gene3053	1.01e-204	580.0	COG2271@1|root,COG2271@2|Bacteria,4NK2M@976|Bacteroidetes,1I107@117743|Flavobacteriia	976|Bacteroidetes	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1048345_1	717773.Thicy_0569	1.17e-06	49.3	COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,46163@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein conserved in bacteria (DUF2058)	-	-	-	ko:K09912	-	-	-	-	ko00000	-	-	-	DUF2058
k59_1048345_2	1123514.KB905899_gene757	6.18e-48	155.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	ppiC	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
k59_1556057_1	317025.Tcr_0242	4.36e-46	163.0	COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,1RP0X@1236|Gammaproteobacteria,460TD@72273|Thiotrichales	72273|Thiotrichales	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_1501640_1	504487.JCM19302_258	5.92e-89	265.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1HWSB@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_1501640_2	1380600.AUYN01000006_gene337	6.06e-159	476.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,1HZ3X@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
k59_712719_1	411154.GFO_2335	2.65e-64	199.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I17E@117743|Flavobacteriia	976|Bacteroidetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_1048364_1	1172190.M947_06265	6.55e-17	80.9	COG1187@1|root,COG1187@2|Bacteria,1QZ1N@1224|Proteobacteria,430HW@68525|delta/epsilon subdivisions,2YS1F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	pseudouridine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1501671_1	1172190.M947_06310	3.65e-151	434.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2YMW2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_30628_1	62928.azo3135	1.14e-91	282.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,2KVQF@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_1386717_1	1278309.KB907101_gene742	2.92e-82	257.0	COG5650@1|root,COG5650@2|Bacteria,1NT6Q@1224|Proteobacteria,1SKE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_370295_1	272123.Anacy_4208	1.44e-22	97.1	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1HM34@1161|Nostocales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_370295_2	709032.Sulku_1860	2.67e-59	205.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_654003_1	411154.GFO_2345	9.71e-97	304.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXPB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_654014_1	1353528.DT23_10650	9.11e-71	230.0	COG1196@1|root,COG1196@2|Bacteria,1QVPK@1224|Proteobacteria,2TXGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_202301_1	637905.SVI_2765	1.39e-49	167.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,2QAW6@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_1127,iUMN146_1321.UM146_11790	Glyco_hydro_3
k59_202301_2	425104.Ssed_2836	4.62e-32	115.0	COG3150@1|root,COG3150@2|Bacteria,1NV1Y@1224|Proteobacteria,1RPQX@1236|Gammaproteobacteria,2QBA5@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0227 family	ycfP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k59_1386740_2	556261.HMPREF0240_03570	4.05e-17	90.5	COG2972@1|root,COG2972@2|Bacteria,1VRFU@1239|Firmicutes,24D70@186801|Clostridia,36R3N@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_540535_1	362418.IW19_00130	3.49e-10	65.5	COG1595@1|root,COG1595@2|Bacteria,4NMFD@976|Bacteroidetes,1IJSE@117743|Flavobacteriia,2P0KU@237|Flavobacterium	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_32635_2	929558.SMGD1_2753	1e-54	173.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2YPGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k59_429939_1	319224.Sputcn32_3671	4.46e-112	341.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RNZX@1236|Gammaproteobacteria,2QAXG@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TonB dependent receptor	viuA	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1672865_1	1187848.AJYQ01000145_gene1526	1.07e-07	50.4	COG5646@1|root,COG5646@2|Bacteria,1N03F@1224|Proteobacteria,1SA9M@1236|Gammaproteobacteria,1XX2F@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_261358_2	1353528.DT23_18875	2.25e-89	274.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2XMDD@285107|Thioclava	28211|Alphaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phbC1	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
k59_1163426_1	317025.Tcr_0062	2.23e-09	55.5	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,1SA5H@1236|Gammaproteobacteria,460VM@72273|Thiotrichales	72273|Thiotrichales	P	oxidoreductase, chain 4L	-	-	1.6.5.3	ko:K00340,ko:K05560	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,3.D.1	-	-	Oxidored_q2
k59_1163426_2	1123517.JOMR01000001_gene360	3.24e-43	159.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,461T6@72273|Thiotrichales	72273|Thiotrichales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	-	-	1.6.5.3	ko:K00341,ko:K05559	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,3.D.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
k59_1786374_1	525898.Sdel_0958	2.91e-94	288.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42MJS@68525|delta/epsilon subdivisions,2YNPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_936426_1	572480.Arnit_0302	8.16e-87	260.0	COG0746@1|root,COG0746@2|Bacteria,1NEIC@1224|Proteobacteria,42SCE@68525|delta/epsilon subdivisions,2YPMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_767932_1	1121931.AUHG01000011_gene1800	5.12e-92	284.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to deoxyribodipyrimidine photolyase	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_1335378_1	1144342.PMI40_01387	6.64e-36	134.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,47329@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_989723_1	1137281.D778_00133	2.79e-313	872.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_826783_1	1392490.JHZX01000001_gene2521	3.06e-63	194.0	2AMQ7@1|root,31CKD@2|Bacteria,4NQVK@976|Bacteroidetes,1I2S8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1276676_1	655815.ZPR_3469	4.99e-60	198.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1HZSJ@117743|Flavobacteriia	976|Bacteroidetes	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_1276676_3	655815.ZPR_3494	2.65e-65	198.0	2DMBC@1|root,32UGK@2|Bacteria,4NUC1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1276676_4	655815.ZPR_3467	3.72e-170	477.0	28J01@1|root,2Z8XB@2|Bacteria,4NGTC@976|Bacteroidetes,1I59G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1276676_5	655815.ZPR_3492	5.22e-85	257.0	COG3504@1|root,COG3504@2|Bacteria,4NH1R@976|Bacteroidetes,1HX3B@117743|Flavobacteriia	976|Bacteroidetes	U	Conjugative transposon TraN protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4138
k59_261412_1	1178825.ALIH01000019_gene1236	1.83e-151	429.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
k59_486889_1	326298.Suden_0215	5.76e-36	128.0	COG0433@1|root,COG0433@2|Bacteria,1Q4H7@1224|Proteobacteria,42Z6M@68525|delta/epsilon subdivisions,2YR7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_486889_2	929558.SMGD1_1011	3.62e-81	245.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2YNU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_430003_1	305700.B447_03123	1.23e-131	380.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria	1224|Proteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	tauK	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_32716_1	1137281.D778_01698	2.44e-98	306.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_277911_1	317025.Tcr_0195	4.48e-95	288.0	COG0745@1|root,COG2172@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,1R7VB@1224|Proteobacteria,1S026@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
k59_788097_1	1137281.D778_02668	8.13e-83	265.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_8
k59_788097_2	1202532.FF52_17638	5.23e-08	53.5	COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,1HY64@117743|Flavobacteriia,2NSDV@237|Flavobacterium	976|Bacteroidetes	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
k59_223699_1	1380600.AUYN01000010_gene842	3.53e-68	232.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_676154_1	323850.Shew_1872	1.04e-154	452.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,2QA04@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_111428_1	1123518.ARWI01000001_gene2056	4.86e-145	418.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	synthase	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
k59_111428_2	1123514.KB905899_gene454	4.46e-11	62.4	COG1577@1|root,COG1577@2|Bacteria,1RIKN@1224|Proteobacteria,1S678@1236|Gammaproteobacteria,46285@72273|Thiotrichales	72273|Thiotrichales	I	GHMP kinases N terminal domain	-	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_51077_1	411154.GFO_1528	1.66e-101	315.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,1HXYW@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC-like,FUSC_2
k59_1464128_1	1123367.C666_15250	1.26e-92	285.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,2KV06@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
k59_1355234_1	326298.Suden_0598	1.18e-68	219.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	ptmE	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k59_842728_1	487316.BBNM01000001_gene1635	3.72e-17	85.5	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,1RQNB@1236|Gammaproteobacteria,3NK3A@468|Moraxellaceae	1236|Gammaproteobacteria	O	XdhC and CoxI family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_788113_1	1137281.D778_02244	5.73e-61	192.0	COG0597@1|root,COG0597@2|Bacteria,4NNP3@976|Bacteroidetes,1I23N@117743|Flavobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_900048_1	616991.JPOO01000003_gene2569	1.8e-101	303.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia,23GFT@178469|Arenibacter	976|Bacteroidetes	C	ATP synthase A chain	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_842764_1	1229205.BUPH_00054	3.23e-06	52.8	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,1K7PY@119060|Burkholderiaceae	28216|Betaproteobacteria	T	UspA domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1183187_1	709032.Sulku_2310	1.2e-79	246.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_842776_1	1168067.JAGP01000001_gene462	1.34e-48	176.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,46172@72273|Thiotrichales	72273|Thiotrichales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_842776_2	1123514.KB905899_gene1632	1.74e-27	110.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_1749566_1	1121931.AUHG01000011_gene1793	9.52e-55	171.0	COG1826@1|root,COG1826@2|Bacteria,4NSAK@976|Bacteroidetes,1I40K@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1749566_2	411154.GFO_2724	1.05e-127	384.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1009382_1	1046627.BZARG_886	1.53e-49	176.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1009382_2	926559.JoomaDRAFT_2871	7.16e-143	419.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1HWZF@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_1464254_1	504487.JCM19302_368	9.27e-147	441.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
k59_1126537_1	323850.Shew_1272	1.01e-32	120.0	COG1694@1|root,COG3956@2|Bacteria,1RIIZ@1224|Proteobacteria,1SBA8@1236|Gammaproteobacteria,2Q98G@267890|Shewanellaceae	1236|Gammaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	TP_methylase
k59_1406677_2	572480.Arnit_0378	1.52e-13	70.5	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1009411_1	929558.SMGD1_1475	7.35e-16	73.2	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
k59_1009411_2	929558.SMGD1_1476	8.97e-11	65.5	COG1413@1|root,COG1413@2|Bacteria,1QZXI@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1406682_2	411154.GFO_2881	4.9e-58	185.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_842866_1	62928.azo3801	1.57e-114	353.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,2KUF2@206389|Rhodocyclales	206389|Rhodocyclales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1524135_1	411154.GFO_2750	1.88e-130	384.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7,NAD_synthase
k59_1464319_1	1250232.JQNJ01000001_gene1563	1.53e-191	543.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HZ5E@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_1692743_1	1487953.JMKF01000012_gene6252	2.04e-29	116.0	COG0726@1|root,COG0726@2|Bacteria,1G5J3@1117|Cyanobacteria,1HH6N@1150|Oscillatoriales	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
k59_223895_1	1117314.PCIT_20134	2.51e-103	306.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,1RP48@1236|Gammaproteobacteria,2Q3NP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k59_448920_1	936455.KI421499_gene7574	4.79e-45	166.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JVPA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
k59_337263_1	929558.SMGD1_0004	2.24e-80	244.0	COG0546@1|root,COG0546@2|Bacteria,1NDKE@1224|Proteobacteria,42SW4@68525|delta/epsilon subdivisions,2YPI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1009479_1	1123518.ARWI01000001_gene2244	2.65e-107	323.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,4604I@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_1009481_1	411154.GFO_2284	1.67e-135	391.0	COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,1HWUP@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
k59_223911_1	1123228.AUIH01000011_gene2033	2.36e-126	371.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1XHDD@135619|Oceanospirillales	135619|Oceanospirillales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_1068812_1	387093.SUN_1855	4.85e-77	254.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1012424_1	1121912.AUHD01000017_gene3506	1.28e-192	550.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_619079_1	1137281.D778_01119	6.41e-128	380.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1HYFW@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_563241_1	491952.Mar181_2638	1.25e-08	55.1	2ERYW@1|root,33JI1@2|Bacteria,1NIJI@1224|Proteobacteria,1SJ4V@1236|Gammaproteobacteria,1XMK1@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_563241_2	1278971.AOGF01000038_gene267	1.22e-11	65.1	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1Y6Z3@135625|Pasteurellales	135625|Pasteurellales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_1580013_1	62928.azo3047	1.48e-119	346.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VKUM@28216|Betaproteobacteria,2KY9I@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_280110_1	387093.SUN_1192	6.17e-61	213.0	COG3287@1|root,COG5001@1|root,COG5002@1|root,COG3287@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,dCache_2
k59_563249_1	1178825.ALIH01000002_gene1045	6.55e-136	397.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_954890_1	1223410.KN050846_gene1142	6.41e-32	125.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1467359_1	572480.Arnit_0959	1.43e-89	265.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_903223_1	313594.PI23P_11277	4.83e-112	337.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia,3VVNA@52959|Polaribacter	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
k59_903223_2	1178825.ALIH01000004_gene2883	2.15e-142	420.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_1467384_1	660470.Theba_1109	6.28e-07	58.5	COG1073@1|root,COG1388@1|root,COG1073@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	CP_0620	-	3.1.3.5,3.5.2.6,3.6.1.45	ko:K06889,ko:K11751,ko:K17836	ko00230,ko00240,ko00311,ko00760,ko01100,ko01110,ko01130,ko01501,map00230,map00240,map00311,map00760,map01100,map01110,map01130,map01501	M00627,M00628	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R06363	RC00017,RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	5_nucleotid_C,Abhydrolase_1,Amidase_2,DLH,Gmad2,Hydrolase_4,LysM,Metallophos,Peptidase_C39_2,Peptidase_S9,SLH
k59_1467384_2	1123037.AUDE01000010_gene2420	1.23e-08	57.4	COG0417@1|root,COG0417@2|Bacteria,4NGEJ@976|Bacteroidetes,1HXZC@117743|Flavobacteriia	976|Bacteroidetes	L	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_395094_1	326298.Suden_0292	2.7e-86	259.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2YN05@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_395094_2	929558.SMGD1_0981	1.85e-65	201.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_280159_1	985255.APHJ01000023_gene2664	9.73e-90	292.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1580080_1	497321.C664_09948	5.68e-09	54.3	COG0640@1|root,COG0640@2|Bacteria,1Q9DY@1224|Proteobacteria,2VVWF@28216|Betaproteobacteria,2KXM8@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_1580080_2	497321.C664_09943	3.21e-58	192.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VI1T@28216|Betaproteobacteria,2KVXK@206389|Rhodocyclales	206389|Rhodocyclales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1467390_1	1168067.JAGP01000001_gene29	1.93e-150	429.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,45ZXW@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_1467390_2	1123518.ARWI01000001_gene1688	1.58e-103	309.0	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1SCBK@1236|Gammaproteobacteria,461D8@72273|Thiotrichales	72273|Thiotrichales	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
k59_845723_1	572480.Arnit_1518	0.000161	52.8	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,42MHY@68525|delta/epsilon subdivisions,2YNDP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	domain protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg_2,Haemagg_act
k59_1012543_1	572480.Arnit_1735	1.41e-153	438.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_451764_1	1123514.KB905901_gene126	5.36e-109	336.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,46089@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k59_1071347_1	411154.GFO_0731	3.52e-150	423.0	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,1HWTK@117743|Flavobacteriia	976|Bacteroidetes	I	intracellular protease amidase	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k59_1071347_2	1121931.AUHG01000016_gene1005	2.77e-62	201.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1HZDH@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1580114_1	1565129.JSFF01000002_gene3413	7.17e-82	249.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria,2QAYK@267890|Shewanellaceae	1236|Gammaproteobacteria	J	S4 RNA-binding domain	rluF	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.21	ko:K06182,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1580114_2	1565129.JSFF01000002_gene3413	2.78e-78	241.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria,2QAYK@267890|Shewanellaceae	1236|Gammaproteobacteria	J	S4 RNA-binding domain	rluF	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.21	ko:K06182,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_280204_1	945713.IALB_1151	1.17e-89	265.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
k59_168432_1	323850.Shew_2940	6.67e-46	149.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,2QCGY@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0250 family	ybeD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k59_168432_2	458817.Shal_3240	3.04e-75	229.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,2Q938@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
k59_1580134_1	563040.Saut_1253	2.55e-94	284.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2YNAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_395168_2	990073.ATHU01000001_gene1768	1.18e-63	197.0	COG1145@1|root,COG1145@2|Bacteria,1QZ2K@1224|Proteobacteria,42SFI@68525|delta/epsilon subdivisions,2YPQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_395168_3	1537917.JU82_10455	8.65e-43	144.0	COG1433@1|root,COG1433@2|Bacteria,1N05Z@1224|Proteobacteria,42VFK@68525|delta/epsilon subdivisions,2YQG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_395168_4	709032.Sulku_1094	3.3e-37	127.0	COG2768@1|root,COG2768@2|Bacteria,1R1K0@1224|Proteobacteria,43DAC@68525|delta/epsilon subdivisions,2YTHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Fer4_9
k59_1467465_1	319224.Sputcn32_0760	6.38e-59	185.0	COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,1S22M@1236|Gammaproteobacteria,2QBQ7@267890|Shewanellaceae	1236|Gammaproteobacteria	N	CheC-like family	cheX	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k59_845776_1	317025.Tcr_0793	1.32e-91	283.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,461CC@72273|Thiotrichales	72273|Thiotrichales	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_280218_2	1379281.AVAG01000040_gene806	2.58e-29	121.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1071376_1	491205.JARQ01000001_gene461	2.56e-16	75.1	COG0110@1|root,COG0110@2|Bacteria,4NTBX@976|Bacteroidetes,1I44C@117743|Flavobacteriia	976|Bacteroidetes	S	Capsule biosynthesis protein CapG	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_1071376_2	946077.W5A_13120	1.1e-25	110.0	COG2244@1|root,COG2244@2|Bacteria,4NFKD@976|Bacteroidetes,1HZ63@117743|Flavobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k59_395181_1	411154.GFO_0429	3.02e-85	257.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_395181_2	411154.GFO_0428	3.34e-31	115.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
k59_451824_1	1123518.ARWI01000001_gene472	8.75e-119	361.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,1T1HI@1236|Gammaproteobacteria,461YR@72273|Thiotrichales	72273|Thiotrichales	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_395187_1	317025.Tcr_1219	1.64e-41	146.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,4613M@72273|Thiotrichales	72273|Thiotrichales	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_691946_2	1121931.AUHG01000012_gene2942	2.81e-97	294.0	COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,1HZ6W@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome bd ubiquinol oxidase, subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_1255454_1	929558.SMGD1_0392	1.59e-78	243.0	COG2404@1|root,COG2404@2|Bacteria,1NHB1@1224|Proteobacteria,42NB0@68525|delta/epsilon subdivisions,2YMQ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_1255454_2	1367491.BN865_09100	6.22e-21	93.2	COG0642@1|root,COG0642@2|Bacteria,1QUJA@1224|Proteobacteria,42MZ2@68525|delta/epsilon subdivisions,2YN1R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	dccS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_239719_1	1123518.ARWI01000001_gene1165	1.47e-162	467.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,46093@72273|Thiotrichales	72273|Thiotrichales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_239719_2	90814.KL370891_gene126	8.78e-105	304.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,460SD@72273|Thiotrichales	72273|Thiotrichales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_239719_3	1123518.ARWI01000001_gene1167	2.29e-62	199.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,45ZQR@72273|Thiotrichales	72273|Thiotrichales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1481980_1	90814.KL370891_gene1178	7.93e-23	94.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,46065@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1537651_2	326298.Suden_0377	8.45e-54	185.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,42PUG@68525|delta/epsilon subdivisions,2YN09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1142190_1	655815.ZPR_3456	9.69e-268	785.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,1HZXU@117743|Flavobacteriia	976|Bacteroidetes	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
k59_1195686_1	504487.JCM19302_1536	6.04e-168	488.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HWPI@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_1195686_2	1123037.AUDE01000013_gene606	2.25e-208	584.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_1195686_3	1347342.BN863_2510	1.27e-129	380.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_634934_1	1178825.ALIH01000007_gene1638	1.28e-109	339.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_747255_2	1121912.AUHD01000004_gene1921	9.17e-37	129.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747255_3	1484460.JSWG01000008_gene1920	3.98e-70	232.0	COG0642@1|root,COG3290@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_860282_1	563040.Saut_2157	4.55e-114	349.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1367924_1	326298.Suden_0861	1.44e-22	90.5	COG3030@1|root,COG3030@2|Bacteria,1N2HX@1224|Proteobacteria,42TXA@68525|delta/epsilon subdivisions,2YQ5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	FxsA cytoplasmic membrane protein	-	-	2.3.3.13	ko:K01649,ko:K07113	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	FxsA
k59_1367924_2	563040.Saut_0906	8.31e-85	266.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_125918_1	1178825.ALIH01000001_gene2308	2.34e-126	366.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1HY0U@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_125918_2	504487.JCM19302_3826	5.79e-108	315.0	COG0527@1|root,COG0527@2|Bacteria,4NJDY@976|Bacteroidetes,1HYZX@117743|Flavobacteriia	976|Bacteroidetes	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_295781_1	1178825.ALIH01000001_gene2536	3.79e-179	513.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_239753_1	1004149.AFOE01000007_gene1395	2.26e-11	64.3	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1I2CE@117743|Flavobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_239753_2	1380600.AUYN01000001_gene2269	5.48e-96	302.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_580272_1	868864.Dester_1351	1e-16	80.1	COG0439@1|root,COG0439@2|Bacteria,2G3K4@200783|Aquificae	200783|Aquificae	I	PFAM Carbamoyl-phosphate synthase L chain	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1484033_1	504487.JCM19302_1154	4.82e-240	671.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1HXT7@117743|Flavobacteriia	976|Bacteroidetes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_1484033_2	1484460.JSWG01000016_gene1622	4.19e-157	452.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_862309_1	1472418.BBJC01000005_gene2209	4.91e-42	149.0	COG0673@1|root,COG0673@2|Bacteria,1MXDE@1224|Proteobacteria,2TSGR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_862309_2	1238450.VIBNISOn1_1210002	1.84e-61	195.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,1S28I@1236|Gammaproteobacteria,1XXPC@135623|Vibrionales	135623|Vibrionales	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k59_1369845_1	929558.SMGD1_0081	5.52e-28	111.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1539529_1	1121931.AUHG01000019_gene3070	3.08e-134	394.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
k59_241706_1	572480.Arnit_0088	9.04e-41	142.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_241706_2	944547.ABLL_0078	1.36e-55	184.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_1315272_1	929558.SMGD1_1182	1.08e-140	439.0	COG3164@1|root,COG3164@2|Bacteria,1QUYX@1224|Proteobacteria,43CES@68525|delta/epsilon subdivisions,2YTC9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1710137_1	572480.Arnit_2786	4.64e-24	96.7	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,42US7@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Transport permease protein	pedC	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_1710137_2	572480.Arnit_2787	7.08e-114	330.0	COG1131@1|root,COG1131@2|Bacteria,1MX56@1224|Proteobacteria	1224|Proteobacteria	V	(ABC) transporter	pedB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_127878_1	62928.azo1529	2.05e-100	309.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2VJ4Z@28216|Betaproteobacteria,2KV5V@206389|Rhodocyclales	206389|Rhodocyclales	P	Kef-type K transport	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k59_127878_2	85643.Tmz1t_2005	7.98e-12	61.6	2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,2VR76@28216|Betaproteobacteria,2KWFX@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_636974_1	1121931.AUHG01000011_gene2366	2.81e-124	372.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_72185_1	62928.azo2691	2.25e-65	216.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,2KUEF@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1426960_3	203275.BFO_3096	2.15e-05	47.8	COG3391@1|root,COG3391@2|Bacteria,4NVSJ@976|Bacteroidetes,2FVH9@200643|Bacteroidia,230RV@171551|Porphyromonadaceae	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
k59_297784_1	1221522.B723_26815	4.3e-11	63.9	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,1SCY7@1236|Gammaproteobacteria,1YR0Q@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
k59_297784_2	1448139.AI20_13700	8.27e-13	69.3	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1Y5F3@135624|Aeromonadales	135624|Aeromonadales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_1087451_1	633148.Tagg_1250	0.000614	41.6	COG1047@1|root,arCOG00980@2157|Archaea,2XQ07@28889|Crenarchaeota	28889|Crenarchaeota	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
k59_1087451_2	1123518.ARWI01000001_gene14	3.11e-27	102.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	Metallothio_Pro
k59_1087451_3	1123518.ARWI01000001_gene15	1.94e-132	385.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,45ZUM@72273|Thiotrichales	72273|Thiotrichales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_353498_2	1123518.ARWI01000001_gene2126	3.15e-64	206.0	COG1073@1|root,COG1073@2|Bacteria,1RD2N@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF1749
k59_580298_1	1175654.A0A0S0NDG6_9CAUD	8.63e-30	114.0	4QDKA@10239|Viruses,4QUPP@35237|dsDNA viruses  no RNA stage,4QPPG@28883|Caudovirales,4QMZH@10699|Siphoviridae	10699|Siphoviridae	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_580298_2	1175654.A0A0S0NAE1_9CAUD	2.63e-43	156.0	4QB0T@10239|Viruses,4QV4X@35237|dsDNA viruses  no RNA stage,4QPUT@28883|Caudovirales,4QKQK@10699|Siphoviridae	10699|Siphoviridae	S	Protein of unknown function (DUF669)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_580298_4	1540098.A0A0A0RW31_9CAUD	1.78e-87	271.0	4QAUT@10239|Viruses,4QQ7X@28883|Caudovirales,4QKVS@10699|Siphoviridae	10699|Siphoviridae	S	DNA ligase (ATP) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_580298_5	1538804.A0A088F7W8_9CAUD	5.38e-131	381.0	4QAR1@10239|Viruses,4QPJE@28883|Caudovirales	28883|Caudovirales	S	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_580298_8	1458669.W6AQW5_9CAUD	1.65e-07	55.1	4QERA@10239|Viruses,4QZRZ@35237|dsDNA viruses  no RNA stage,4QQTQ@28883|Caudovirales,4QME6@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1369896_1	1443665.JACA01000001_gene2647	2.17e-38	130.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1I3YR@117743|Flavobacteriia,2YJUV@290174|Aquimarina	976|Bacteroidetes	O	F plasmid transfer operon protein	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1369896_2	398720.MED217_02590	4.98e-54	172.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2XK92@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_72215_1	983544.Lacal_0135	3.34e-151	457.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1144063_1	1121931.AUHG01000010_gene490	2.65e-22	90.9	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia	976|Bacteroidetes	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_1144063_2	1121931.AUHG01000010_gene491	6.79e-24	91.7	2DP68@1|root,330PW@2|Bacteria,4NWJ3@976|Bacteroidetes,1I584@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1144063_3	1121931.AUHG01000010_gene492	5.03e-38	132.0	COG0492@1|root,COG0492@2|Bacteria,4NHKD@976|Bacteroidetes,1I1D6@117743|Flavobacteriia	976|Bacteroidetes	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_1257484_2	1123517.JOMR01000001_gene1888	6.27e-51	178.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_694053_1	1392489.JPOL01000002_gene2231	1.28e-96	294.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia,2XI36@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_694053_2	1380600.AUYN01000007_gene3436	7.26e-67	213.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
k59_467654_2	90814.KL370892_gene2326	2.22e-20	89.7	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria,46275@72273|Thiotrichales	72273|Thiotrichales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_1597587_1	90813.JQMT01000001_gene544	1.29e-120	353.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales	72273|Thiotrichales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_185358_1	1380600.AUYN01000009_gene2047	9.61e-99	294.0	2C793@1|root,2Z9MK@2|Bacteria,4NI6K@976|Bacteroidetes,1HWYK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_72230_1	1178825.ALIH01000015_gene1887	1.25e-84	254.0	COG1011@1|root,COG1011@2|Bacteria,4NF0Y@976|Bacteroidetes,1HZ7Q@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
k59_72230_2	1380600.AUYN01000001_gene2321	3.79e-119	348.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes,1IMM0@117743|Flavobacteriia	976|Bacteroidetes	C	Alcohol dehydrogenase class IV	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k59_185366_1	1121931.AUHG01000011_gene2286	8.23e-50	179.0	COG3209@1|root,COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Reprolysin_4,TSP_3
k59_1427009_1	714943.Mucpa_1832	5.14e-33	134.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_1427009_2	1454007.JAUG01000054_gene2590	1.06e-34	137.0	COG0383@1|root,COG0383@2|Bacteria,4NEC3@976|Bacteroidetes,1IX18@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Glyco_hydro_38,Glyco_hydro_38C
k59_1197096_1	1123514.KB905899_gene1693	6.83e-07	48.9	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,460JZ@72273|Thiotrichales	72273|Thiotrichales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_1197096_2	317025.Tcr_0409	5.17e-58	189.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,46095@72273|Thiotrichales	72273|Thiotrichales	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_523492_1	1123228.AUIH01000002_gene1465	5.93e-65	205.0	COG5581@1|root,COG5581@2|Bacteria,1NBKC@1224|Proteobacteria,1SEUT@1236|Gammaproteobacteria,1XMGR@135619|Oceanospirillales	135619|Oceanospirillales	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
k59_1087481_2	1392490.JHZX01000001_gene344	2.12e-151	432.0	COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,1HYZ6@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1087481_3	1392490.JHZX01000001_gene345	0.0	961.0	COG1435@1|root,COG1435@2|Bacteria,4PMQ9@976|Bacteroidetes,1HY5Z@117743|Flavobacteriia	976|Bacteroidetes	F	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1087481_4	1086011.HJ01_01512	1.32e-230	665.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia,2NVUD@237|Flavobacterium	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_637060_1	1042375.AFPL01000027_gene3360	3.54e-68	218.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,46675@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_1597627_1	693986.MOC_6085	2.22e-26	103.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2TS23@28211|Alphaproteobacteria,1JU4N@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	TIGRFAM urea ABC transporter, ATP-binding protein UrtE	MA20_23050	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
k59_1597627_2	1046714.AMRX01000008_gene1023	3.49e-122	359.0	COG2421@1|root,COG2421@2|Bacteria,1MVRT@1224|Proteobacteria,1RQDU@1236|Gammaproteobacteria,4641U@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acetamidase formamidase	fmdA	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
k59_862432_1	1123518.ARWI01000001_gene1568	7.13e-24	99.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,4605D@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
k59_862432_2	1123518.ARWI01000001_gene1567	2.51e-76	230.0	COG1516@1|root,COG1516@2|Bacteria	2|Bacteria	N	flagellar protein fliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_257645_1	323850.Shew_2716	7.14e-102	312.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria,2Q9HB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_985612_1	504487.JCM19302_2401	1.23e-106	315.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HYY3@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_985612_2	1178825.ALIH01000002_gene880	2.4e-164	464.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1HXM2@117743|Flavobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_985612_4	688270.Celal_4276	2.48e-116	340.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia,1FA2B@104264|Cellulophaga	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_538796_1	243231.GSU1630	2.21e-14	72.8	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZD5@68525|delta/epsilon subdivisions,2WUEK@28221|Deltaproteobacteria,43TFW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, HAMP and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,sCache_3_2
k59_538796_2	1232410.KI421413_gene533	1.38e-24	100.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,43S9H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1499804_1	326298.Suden_0484	3.06e-53	174.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,42MG5@68525|delta/epsilon subdivisions,2YN7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_425945_1	326298.Suden_1767	4.91e-67	218.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_257670_1	1278309.KB907099_gene2537	1.89e-77	253.0	COG2911@1|root,COG2911@2|Bacteria,1MUT7@1224|Proteobacteria,1RQ5W@1236|Gammaproteobacteria,1XJRI@135619|Oceanospirillales	135619|Oceanospirillales	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
k59_538814_1	582744.Msip34_2344	8.97e-32	125.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,2KMDP@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_538814_2	1150626.PHAMO_270022	1.35e-14	73.2	2ATZM@1|root,31JJE@2|Bacteria,1RIFX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_368504_1	572480.Arnit_2579	4.57e-39	135.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	cprR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1208682_1	572480.Arnit_1409	8.16e-73	225.0	COG0810@1|root,COG0810@2|Bacteria,1MZB7@1224|Proteobacteria,42U57@68525|delta/epsilon subdivisions,2YQ1F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1208682_2	572480.Arnit_1408	2.74e-17	79.3	COG0685@1|root,COG0685@2|Bacteria,1QGEE@1224|Proteobacteria,42MYR@68525|delta/epsilon subdivisions,2YMH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_712849_1	257310.BB1469	3.01e-99	294.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,3T1WB@506|Alcaligenaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_144619_1	1347342.BN863_29670	4.97e-41	142.0	COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,1I2VP@117743|Flavobacteriia	976|Bacteroidetes	M	NlpC P60 family	nlpC	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	LysM,NLPC_P60
k59_144619_2	504487.JCM19302_228	2.33e-06	47.8	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_202378_1	1172190.M947_07320	5.64e-25	102.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria	1224|Proteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_202378_2	929558.SMGD1_0965	1.23e-38	135.0	29DRS@1|root,32N9S@2|Bacteria,1PPR2@1224|Proteobacteria,432TA@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1670822_1	1380600.AUYN01000007_gene3045	1.15e-93	290.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1670822_2	1178825.ALIH01000009_gene1356	3.69e-48	159.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1386813_1	929558.SMGD1_2870	1.28e-85	264.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,42MUQ@68525|delta/epsilon subdivisions,2YMUB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium calcium exchanger membrane	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
k59_1556211_1	317025.Tcr_1586	1.44e-36	130.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	COG1291 Flagellar motor component	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_1556211_2	317025.Tcr_1587	3.09e-11	65.1	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_202379_1	1121931.AUHG01000011_gene2413	2.77e-104	316.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,1HZYC@117743|Flavobacteriia	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_1727159_1	95619.PM1_0206705	3.35e-45	166.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1S01Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_484872_1	317025.Tcr_0191	7.08e-161	462.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,460GP@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_484872_2	1087481.AGFX01000011_gene3906	9.01e-10	61.2	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,26RTF@186822|Paenibacillaceae	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
k59_1208703_1	1178825.ALIH01000001_gene2440	2.31e-134	383.0	COG2197@1|root,COG2197@2|Bacteria,4NHNP@976|Bacteroidetes,1I09Z@117743|Flavobacteriia	976|Bacteroidetes	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1333236_1	1121861.KB899941_gene3846	8.39e-23	98.2	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2JWBG@204441|Rhodospirillales	204441|Rhodospirillales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_484873_1	1123518.ARWI01000001_gene592	1.28e-06	48.9	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,4631P@72273|Thiotrichales	72273|Thiotrichales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	-	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k59_484873_2	90814.KL370891_gene720	9.62e-76	248.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_879457_1	317025.Tcr_2051	2.99e-06	48.1	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,460DH@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_879457_2	1123518.ARWI01000001_gene1312	7.38e-130	373.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,4606Q@72273|Thiotrichales	72273|Thiotrichales	L	Exodeoxyribonuclease III xth	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_654118_1	1250005.PHEL85_1102	4.26e-99	312.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia,3VX58@52959|Polaribacter	976|Bacteroidetes	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_765941_1	1007105.PT7_0805	2.48e-88	271.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,3T1SD@506|Alcaligenaceae	28216|Betaproteobacteria	G	C4-dicarboxylate ABC transporter permease	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_1386850_2	1380600.AUYN01000005_gene2936	6.25e-65	211.0	arCOG14015@1|root,30H02@2|Bacteria,4NNVX@976|Bacteroidetes,1I680@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1386850_3	1121897.AUGO01000002_gene2482	1.08e-20	89.4	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,1HWQE@117743|Flavobacteriia,2NTCI@237|Flavobacterium	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_30763_1	440512.C211_00497	4.35e-09	57.4	COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
k59_30763_2	1250278.JQNQ01000001_gene3233	1.01e-57	186.0	COG4302@1|root,COG4302@2|Bacteria,4NH0M@976|Bacteroidetes,1I7DY@117743|Flavobacteriia	976|Bacteroidetes	E	Ethanolamine ammonia-lyase light chain (EutC)	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
k59_1556253_1	572480.Arnit_2449	3.21e-119	361.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_1501845_1	1121007.AUML01000025_gene17	1.87e-32	129.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia,2YHBX@290174|Aquimarina	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208,ko:K21575	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_765957_1	62928.azo3134	7.19e-107	336.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KV6Z@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1727212_1	411154.GFO_2323	2.82e-168	491.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1784581_1	1380600.AUYN01000006_gene362	2.86e-169	484.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_879514_1	1565129.JSFF01000014_gene408	2.96e-78	240.0	28MF7@1|root,2ZASQ@2|Bacteria,1R80F@1224|Proteobacteria,1RP72@1236|Gammaproteobacteria,2QA0S@267890|Shewanellaceae	1236|Gammaproteobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
k59_824692_1	985255.APHJ01000027_gene918	5.88e-38	148.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NHMH@976|Bacteroidetes,1HZTE@117743|Flavobacteriia	976|Bacteroidetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
k59_30800_1	411154.GFO_0779	1.37e-80	249.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_30800_2	655815.ZPR_1676	1.73e-16	78.2	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1501886_1	226186.BT_0614	9.37e-33	132.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,2FM9K@200643|Bacteroidia,4AKKD@815|Bacteroidaceae	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_484947_1	411154.GFO_1485	1.49e-05	46.6	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_484947_2	411154.GFO_1486	1.45e-89	263.0	COG1522@1|root,COG1522@2|Bacteria,4NHG9@976|Bacteroidetes,1HXEQ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_30804_1	1392489.JPOL01000002_gene1854	8.54e-113	354.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2XKGC@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_144720_1	886377.Murru_2965	3.2e-52	177.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_144720_2	313598.MED152_06655	7.39e-30	106.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,3VWVB@52959|Polaribacter	976|Bacteroidetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_144720_3	1347342.BN863_11100	5.45e-27	100.0	2E92X@1|root,333BW@2|Bacteria,4NV09@976|Bacteroidetes,1I50R@117743|Flavobacteriia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
k59_144720_4	1178825.ALIH01000006_gene1454	6e-250	695.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1HXV7@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_370487_1	1121931.AUHG01000020_gene3157	7.26e-70	220.0	COG0545@1|root,COG0545@2|Bacteria,4NNK2@976|Bacteroidetes,1I2FD@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_370487_2	411154.GFO_1879	8.86e-91	275.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1HXF8@117743|Flavobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_654197_1	768671.ThimaDRAFT_4426	5.16e-134	394.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_427994_1	326298.Suden_0623	9.26e-97	294.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2YMVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	phosphomannomutase	glmM_1	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_427994_2	326298.Suden_0651	3.79e-39	141.0	COG1462@1|root,COG1462@2|Bacteria,1R8Z9@1224|Proteobacteria,42XNA@68525|delta/epsilon subdivisions,2YR9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_1274719_1	1297863.APJF01000020_gene2728	2.7e-12	68.6	COG0834@1|root,COG0834@2|Bacteria,1NN6F@1224|Proteobacteria,2TSA4@28211|Alphaproteobacteria,3JVI5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	ET	Ligand-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Lig_chan,SBP_bac_3
k59_1727270_1	338966.Ppro_0333	1.29e-32	114.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria,43SS6@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k59_1727270_2	1232410.KI421421_gene3514	7.73e-13	62.4	2ER59@1|root,33IQV@2|Bacteria,1NMF6@1224|Proteobacteria,42Y36@68525|delta/epsilon subdivisions,2WT0Q@28221|Deltaproteobacteria,43VTT@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1501914_1	313598.MED152_09025	8.95e-10	60.8	COG0457@1|root,COG3103@1|root,COG0457@2|Bacteria,COG3103@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia,3VVPU@52959|Polaribacter	976|Bacteroidetes	T	Bacterial SH3 domain homologues	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
k59_1386942_1	1380600.AUYN01000009_gene1155	5.24e-38	143.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1386942_2	641526.ADIWIN_2246	6.51e-221	610.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1HWQC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_1386942_3	1178825.ALIH01000007_gene1654	4.28e-151	427.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_1386942_4	1353276.JADR01000008_gene841	3.39e-07	50.8	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_1670965_1	504487.JCM19302_2705	3.47e-58	188.0	COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1HX87@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_1670965_2	865937.Gilli_2227	2.14e-29	110.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia,2P607@244698|Gillisia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_1670969_1	313606.M23134_02780	1.27e-44	163.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47M4M@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_1333386_1	945713.IALB_0332	1.16e-25	106.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
k59_1333386_2	945713.IALB_0329	2.54e-48	164.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11	ko:K10960,ko:K17830	ko00564,ko00860,ko00900,ko01100,ko01110,map00564,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R10325,R10326,R10331,R11226,R11518	RC00212,RC00522,RC01823,RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
k59_1208777_1	929558.SMGD1_1491	5.33e-87	283.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42MR5@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
k59_540762_1	755732.Fluta_2829	1.65e-10	67.0	COG1520@1|root,COG1520@2|Bacteria,4NJHN@976|Bacteroidetes,1HZTN@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_713032_1	1123518.ARWI01000001_gene1173	4.33e-34	127.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales	72273|Thiotrichales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_713032_2	1123514.KB905899_gene1927	4.07e-94	278.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,1T23F@1236|Gammaproteobacteria,4612X@72273|Thiotrichales	72273|Thiotrichales	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_202537_1	411154.GFO_0273	9.99e-139	402.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1HWPY@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_202541_1	90814.KL370891_gene955	9.29e-66	219.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_485021_1	411154.GFO_2292	1.19e-13	69.3	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_89467_1	497321.C664_02660	2.11e-60	191.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,2KW20@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_89467_2	305700.B447_17983	3.68e-21	88.2	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,2KVHW@206389|Rhodocyclales	206389|Rhodocyclales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
k59_654281_1	136273.GY22_04880	8.5e-07	49.3	COG2314@1|root,COG2314@2|Bacteria,2GUWS@201174|Actinobacteria,1WA6W@1268|Micrococcaceae	201174|Actinobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
k59_654281_2	572480.Arnit_2157	2.71e-59	186.0	COG0317@1|root,COG0317@2|Bacteria,1RCK7@1224|Proteobacteria,42SEV@68525|delta/epsilon subdivisions	1224|Proteobacteria	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
k59_1048669_1	1353276.JADR01000008_gene888	4.26e-87	283.0	COG0841@1|root,COG0841@2|Bacteria,4NGVM@976|Bacteroidetes,1HYZV@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1443664_1	1178825.ALIH01000001_gene2381	1.51e-264	731.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_879651_1	1380600.AUYN01000001_gene2459	1.47e-61	194.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,1I3ZA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1556423_1	1348583.ATLH01000017_gene2611	6.02e-22	92.4	COG3279@1|root,COG3279@2|Bacteria,4NIYZ@976|Bacteroidetes,1HWVK@117743|Flavobacteriia,1F882@104264|Cellulophaga	976|Bacteroidetes	K	COGs COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_502833_1	411154.GFO_1004	4.57e-113	332.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1HWW9@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
k59_502833_2	411154.GFO_1003	5.05e-10	58.9	COG1377@1|root,COG1377@2|Bacteria,4NMN3@976|Bacteroidetes,1I174@117743|Flavobacteriia	976|Bacteroidetes	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1123201_1	62928.azo0558	3.2e-81	242.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2VQYS@28216|Betaproteobacteria,2KWCX@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_1123201_2	580332.Slit_0908	5.77e-26	97.4	2DQ5Y@1|root,334WI@2|Bacteria,1QWGA@1224|Proteobacteria,2VWW1@28216|Betaproteobacteria,44WJN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
k59_1065435_1	90814.KL370891_gene697	4.94e-116	348.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,460A5@72273|Thiotrichales	72273|Thiotrichales	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1065435_2	317025.Tcr_1443	7.89e-18	77.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,4617T@72273|Thiotrichales	72273|Thiotrichales	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k59_333715_1	682795.AciX8_3374	6.54e-13	70.1	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_1065450_1	1121931.AUHG01000015_gene1185	1.42e-141	429.0	COG1629@1|root,COG1629@2|Bacteria,4PM06@976|Bacteroidetes,1IJK3@117743|Flavobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_1629380_3	85643.Tmz1t_0254	6.6e-23	96.3	COG3481@1|root,COG3481@2|Bacteria,1QVI0@1224|Proteobacteria,2W27G@28216|Betaproteobacteria,2KZWJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
k59_445442_1	1178825.ALIH01000006_gene1437	1.26e-96	293.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_1460879_1	944547.ABLL_0037	3.9e-12	67.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07717,ko:K13040,ko:K13924	ko02020,ko02030,map02020,map02030	M00506,M00514,M00518	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,NMT1,PAS,PAS_9,SBP_bac_3
k59_1460879_2	944546.ABED_0821	1.19e-39	147.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_388747_1	1353528.DT23_17275	6.42e-158	451.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,2TTA9@28211|Alphaproteobacteria,2XMSP@285107|Thioclava	28211|Alphaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1293000_1	1123514.KB905901_gene86	8.72e-42	153.0	2DNAT@1|root,32WH7@2|Bacteria,1N2AT@1224|Proteobacteria,1SIPZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_557200_1	563040.Saut_1880	6.25e-108	331.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_502914_1	929558.SMGD1_1848	3.04e-69	217.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_502914_2	929558.SMGD1_1847	5.24e-60	192.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria	1224|Proteobacteria	H	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_896757_1	1123518.ARWI01000001_gene2144	1.56e-154	438.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,46025@72273|Thiotrichales	72273|Thiotrichales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_896757_2	795666.MW7_0390	0.000121	43.9	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,1K3DI@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1802985_1	1408321.JNJD01000006_gene1204	8.44e-16	82.8	COG2206@1|root,COG2206@2|Bacteria,1UN6E@1239|Firmicutes,25GXR@186801|Clostridia,27JDI@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_220738_1	1355368.JART01000015_gene1897	4.68e-27	102.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_220738_2	1537917.JU82_03450	9.63e-33	120.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_1293022_1	929558.SMGD1_1147	1.01e-18	84.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1293022_2	326298.Suden_2009	7.63e-47	156.0	2BEW6@1|root,328MU@2|Bacteria,1QAUA@1224|Proteobacteria,42VY6@68525|delta/epsilon subdivisions,2YQED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_784931_1	1117315.AHCA01000001_gene2604	8.91e-37	140.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,2Q0MJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	COG0542 ATPases with chaperone activity, ATP-binding subunit	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1460935_1	572480.Arnit_0296	2.28e-95	294.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_108105_1	504487.JCM19302_1558	6.19e-114	365.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_275278_1	929558.SMGD1_0633	4.18e-48	174.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_275278_2	929558.SMGD1_2212	2.99e-61	209.0	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_47905_1	1250005.PHEL85_3176	8.17e-110	344.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia,3VWZU@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_731679_1	1380600.AUYN01000009_gene1645	2.39e-105	310.0	COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,1HXZW@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_731679_2	1122226.AUHX01000004_gene1650	1.2e-53	170.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_731679_3	1380600.AUYN01000009_gene1643	1.04e-106	319.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1520769_1	225849.swp_4920	6.33e-96	306.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q8PH@267890|Shewanellaceae	1236|Gammaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	acrB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_162254_1	207954.MED92_11144	2.61e-16	75.5	COG1280@1|root,COG1280@2|Bacteria,1RAI3@1224|Proteobacteria,1S2GP@1236|Gammaproteobacteria,1XJ9E@135619|Oceanospirillales	135619|Oceanospirillales	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_162254_2	572480.Arnit_0482	1.32e-84	251.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2YPXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_162254_3	572480.Arnit_0481	2.62e-67	204.0	COG0858@1|root,COG0858@2|Bacteria,1Q48R@1224|Proteobacteria,42UQE@68525|delta/epsilon subdivisions,2YPZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_896795_1	1341155.FSS13T_24420	2.03e-25	114.0	COG4409@1|root,COG4409@2|Bacteria,4PM7K@976|Bacteroidetes,1IJKJ@117743|Flavobacteriia,2NTU2@237|Flavobacterium	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10,fn3
k59_445538_1	312153.Pnuc_1259	4.32e-29	114.0	COG0726@1|root,COG0726@2|Bacteria,1MX3V@1224|Proteobacteria,2VJVH@28216|Betaproteobacteria,1K51Q@119060|Burkholderiaceae	28216|Betaproteobacteria	G	deacetylase	pdaA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1403988_1	1089551.KE386572_gene2566	3.58e-94	279.0	2DB7P@1|root,2Z7MR@2|Bacteria,1RE7E@1224|Proteobacteria,2U7NS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162284_1	1134474.O59_002256	2.48e-94	308.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1FGF3@10|Cellvibrio	1236|Gammaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1293100_1	1380600.AUYN01000010_gene866	5.99e-147	437.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_503003_1	693661.Arcve_1359	1.44e-12	73.2	COG3291@1|root,COG3979@1|root,arCOG02499@1|root,arCOG02552@1|root,arCOG03439@1|root,arCOG02499@2157|Archaea,arCOG02552@2157|Archaea,arCOG03439@2157|Archaea,arCOG03504@2157|Archaea,arCOG07581@2157|Archaea,2XXWR@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
k59_1461006_1	1121935.AQXX01000117_gene5081	2.02e-62	214.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU6Y@1224|Proteobacteria,1RM7Z@1236|Gammaproteobacteria,1XH99@135619|Oceanospirillales	135619|Oceanospirillales	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
k59_388862_1	1484460.JSWG01000015_gene1026	2.78e-15	77.4	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG3420@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
k59_388862_2	1353276.JADR01000001_gene280	2.58e-105	344.0	COG1345@1|root,COG3227@1|root,COG3897@1|root,COG1345@2|Bacteria,COG3227@2|Bacteria,COG3897@2|Bacteria,4PNP2@976|Bacteroidetes	976|Bacteroidetes	EN	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,MAM
k59_1006058_1	326298.Suden_1781	1.02e-47	164.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1006058_2	563040.Saut_0425	3.28e-16	77.4	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2YN86@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	cbrR	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_503016_1	243159.AFE_1544	4.3e-27	110.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,2NDHA@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Belongs to the NadC ModD family	-	-	-	ko:K03813	-	-	-	-	ko00000,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_1006061_2	391623.TERMP_00517	1.99e-10	64.3	COG2236@1|root,arCOG00040@2157|Archaea,2XU0E@28890|Euryarchaeota,24312@183968|Thermococci	183968|Thermococci	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_785022_1	1168067.JAGP01000001_gene519	3.27e-36	134.0	COG0026@1|root,COG0026@2|Bacteria	2|Bacteria	F	5-(carboxyamino)imidazole ribonucleotide synthase activity	-	-	6.3.4.18,6.3.5.5	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	M00048,M00051	R00256,R00575,R01395,R07404,R10011,R10948,R10949	RC00002,RC00010,RC00043,RC00096,RC00141,RC01927,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,ATP-grasp_4
k59_785022_2	1235798.C817_01377	9.66e-12	65.5	COG2242@1|root,COG2242@2|Bacteria,1UIES@1239|Firmicutes,25EK6@186801|Clostridia	186801|Clostridia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_1225671_1	985054.JQEZ01000001_gene1867	4.25e-32	127.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,4NBYM@97050|Ruegeria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130,ko:K01138	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_731754_1	90814.KL370891_gene1718	7.86e-51	178.0	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,1SFE3@1236|Gammaproteobacteria,461HT@72273|Thiotrichales	72273|Thiotrichales	NU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_731754_2	90814.KL370891_gene1717	7.04e-39	144.0	COG2165@1|root,COG2931@1|root,COG2165@2|Bacteria,COG2931@2|Bacteria,1RHE1@1224|Proteobacteria,1SFE3@1236|Gammaproteobacteria,461HT@72273|Thiotrichales	72273|Thiotrichales	NU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_612994_1	1121931.AUHG01000015_gene1143	2e-98	290.0	COG3332@1|root,COG3332@2|Bacteria,4NMN7@976|Bacteroidetes,1I1KH@117743|Flavobacteriia	976|Bacteroidetes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
k59_108197_1	76114.ebA4979	5.51e-19	85.1	COG0282@1|root,COG0664@1|root,COG4869@1|root,COG0282@2|Bacteria,COG0664@2|Bacteria,COG4869@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,2KXZH@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	-	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
k59_108197_2	1380391.JIAS01000014_gene2026	2.47e-66	208.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2TURT@28211|Alphaproteobacteria,2JQTU@204441|Rhodospirillales	204441|Rhodospirillales	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1629483_1	929558.SMGD1_1528	5.6e-94	288.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2YN87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	nikZ	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1803118_1	1121931.AUHG01000011_gene1631	7.02e-70	223.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1803118_2	411154.GFO_2892	2.13e-52	179.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_1404058_1	1121875.KB907549_gene1752	1.79e-52	172.0	2BVY1@1|root,32QYH@2|Bacteria,4NR2M@976|Bacteroidetes,1I3HA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1520881_1	929558.SMGD1_0192	1.93e-64	216.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42NJQ@68525|delta/epsilon subdivisions,2YMZP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	hmm pf00563	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_1520885_1	1189619.pgond44_02413	6.79e-22	100.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1IIPI@117743|Flavobacteriia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
k59_1520902_1	572480.Arnit_1226	5.49e-128	373.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2YNPQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Abc transporter, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_503075_1	1123514.KB905902_gene198	1.1e-17	80.9	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_503075_2	90814.KL370892_gene2318	6.22e-57	188.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1SN75@1236|Gammaproteobacteria,462AW@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1746397_1	572480.Arnit_2477	1.88e-88	279.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	yibG	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_16,TPR_8
k59_1573881_1	1469557.JSWF01000014_gene2601	7.6e-76	244.0	COG1216@1|root,COG4123@1|root,COG1216@2|Bacteria,COG4123@2|Bacteria,4NFEP@976|Bacteroidetes,1HWUH@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_1352142_1	1229487.AMYW01000005_gene178	2.28e-21	88.6	COG1846@1|root,COG1846@2|Bacteria,4NRHI@976|Bacteroidetes,1I3R3@117743|Flavobacteriia,2NW6N@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
k59_1352142_2	1286632.P278_07490	7.39e-52	175.0	COG0457@1|root,COG2819@1|root,COG0457@2|Bacteria,COG2819@2|Bacteria,4NN8M@976|Bacteroidetes,1I1EI@117743|Flavobacteriia	976|Bacteroidetes	NU	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_48053_1	929558.SMGD1_2392	6.59e-222	621.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1006148_1	90814.KL370891_gene1545	8.18e-76	243.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,460HX@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_1352163_1	1121895.Q765_00230	5.6e-73	231.0	2C54U@1|root,2ZB6X@2|Bacteria,4NJRR@976|Bacteroidetes,1I0H8@117743|Flavobacteriia,2NVPV@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2586
k59_1689531_1	305700.B447_00385	1.52e-21	86.7	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1689531_2	85643.Tmz1t_2648	1.69e-50	178.0	COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,2KUQR@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1295805_1	1121931.AUHG01000011_gene1988	3.96e-158	478.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_50608_1	305700.B447_09413	6.69e-25	99.8	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_50608_3	883126.HMPREF9710_04685	2.03e-38	133.0	2DRNC@1|root,33CCS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_110882_1	1323663.AROI01000026_gene1872	3.02e-39	145.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_110882_2	1380600.AUYN01000009_gene1189	1.16e-08	55.5	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_899519_1	1121931.AUHG01000012_gene2574	4.66e-40	134.0	COG0236@1|root,COG0236@2|Bacteria,4NUSD@976|Bacteroidetes,1I5HU@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl carrier protein	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_899519_2	411154.GFO_1607	1.65e-26	107.0	COG0304@1|root,COG0304@2|Bacteria,4NDXP@976|Bacteroidetes,1HXYM@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_675679_1	1121931.AUHG01000011_gene1967	4.12e-128	373.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_615607_1	1250232.JQNJ01000001_gene528	3.19e-68	218.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1HXVN@117743|Flavobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_1463604_1	1484460.JSWG01000008_gene2048	3.8e-95	283.0	COG0637@1|root,COG0637@2|Bacteria,4NPDJ@976|Bacteroidetes,1HWWS@117743|Flavobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1463604_2	504487.JCM19302_2319	1.2e-126	364.0	COG0300@1|root,COG0300@2|Bacteria,4NEFB@976|Bacteroidetes,1HX0Q@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1463604_3	1121912.AUHD01000017_gene3507	1.66e-141	409.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1HYWG@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_1228336_1	1123228.AUIH01000026_gene3874	1.01e-52	173.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,1XI7I@135619|Oceanospirillales	135619|Oceanospirillales	T	response regulator	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
k59_1760472_1	1123037.AUDE01000016_gene281	1.55e-50	168.0	2CA54@1|root,30DBK@2|Bacteria,4NNK9@976|Bacteroidetes,1I237@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1760472_2	504487.JCM19302_1772	3.6e-25	100.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1081538_1	1121931.AUHG01000010_gene286	3.69e-116	340.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1081538_2	411154.GFO_3302	1.68e-173	495.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1192862_1	367737.Abu_0987	9.5e-50	172.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,42RMX@68525|delta/epsilon subdivisions,2YTP4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
k59_1192862_2	525897.Dbac_1149	4.18e-07	51.6	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2WUYC@28221|Deltaproteobacteria,2MCVA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1138335_1	1469557.JSWF01000015_gene2726	9.15e-105	312.0	COG0561@1|root,COG0561@2|Bacteria,4NG7K@976|Bacteroidetes,1HY6R@117743|Flavobacteriia	976|Bacteroidetes	S	of the HAD superfamily	supH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_1138335_2	1250232.JQNJ01000001_gene2453	1.46e-78	236.0	COG0432@1|root,COG0432@2|Bacteria,4NNMN@976|Bacteroidetes,1I21B@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_1138335_3	1380600.AUYN01000001_gene2777	1.09e-37	132.0	2E3XJ@1|root,32YUM@2|Bacteria,4NV86@976|Bacteroidetes,1I58H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1363885_3	1123518.ARWI01000001_gene655	1.83e-52	170.0	COG3018@1|root,COG3018@2|Bacteria,1N8R1@1224|Proteobacteria,1T0JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k59_404718_1	411154.GFO_3578	3.64e-110	328.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_404718_2	411154.GFO_3577	1.03e-40	137.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I27K@117743|Flavobacteriia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1251356_1	572480.Arnit_0668	4.44e-68	228.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_517197_1	641526.ADIWIN_1042	1.76e-09	60.1	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_517197_2	504487.JCM19302_2120	3.56e-61	191.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_517199_1	1123518.ARWI01000001_gene2389	3.17e-80	253.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_8857_1	1121931.AUHG01000020_gene3135	2e-66	205.0	COG1595@1|root,COG1595@2|Bacteria,4NFXX@976|Bacteroidetes,1HZT5@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_121937_1	313596.RB2501_07290	3.51e-153	461.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_687588_1	1123518.ARWI01000001_gene850	2.42e-76	239.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,460RX@72273|Thiotrichales	72273|Thiotrichales	L	ATP dependent DNA ligase domain	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_687588_2	1123514.KB905899_gene1657	1.1e-09	55.5	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k59_347508_1	1380600.AUYN01000003_gene37	1.29e-20	91.3	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_347508_2	1380600.AUYN01000003_gene36	4.62e-140	402.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_179092_1	929558.SMGD1_1181	1.56e-132	384.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,42P59@68525|delta/epsilon subdivisions,2YMPJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0324 family	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_1138366_1	317025.Tcr_0777	3.13e-66	233.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1192898_1	929558.SMGD1_0820	7.04e-138	406.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2YMBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1251401_1	317025.Tcr_2040	5.09e-119	349.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,45ZXH@72273|Thiotrichales	72273|Thiotrichales	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_630670_2	754477.Q7C_2064	3.95e-65	220.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,463VX@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_235666_1	1116375.VEJY3_06550	1.32e-115	347.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales	135623|Vibrionales	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_179100_1	1380600.AUYN01000001_gene2457	2.43e-114	332.0	COG5403@1|root,COG5403@2|Bacteria,4NEX0@976|Bacteroidetes,1HYHW@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
k59_179100_2	504487.JCM19302_39	2.01e-199	555.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1HWXS@117743|Flavobacteriia	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_179100_3	1178825.ALIH01000012_gene1832	8.89e-229	633.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_179100_4	1178825.ALIH01000012_gene1831	3.56e-109	323.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
k59_347543_1	1123514.KB905899_gene938	1.31e-17	80.5	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,4605I@72273|Thiotrichales	72273|Thiotrichales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_347543_2	1123518.ARWI01000001_gene135	8.68e-68	216.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,45ZPT@72273|Thiotrichales	72273|Thiotrichales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_1192917_1	411154.GFO_2157	2.33e-129	378.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HZ6Y@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1192917_2	1121931.AUHG01000011_gene2213	2.3e-34	125.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k59_630692_1	326298.Suden_1997	5.73e-48	156.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2YQ0W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
k59_630692_2	1042876.PPS_0677	2.34e-14	74.3	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,1RRQ0@1236|Gammaproteobacteria,1YXA4@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_1138403_2	1443665.JACA01000043_gene1487	5.63e-243	675.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1HXW7@117743|Flavobacteriia,2YGJH@290174|Aquimarina	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	nagA	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_1081637_1	929558.SMGD1_2447	1.14e-99	314.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2YMQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_912743_1	1406840.Q763_04185	4.75e-210	599.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia,2NTC3@237|Flavobacterium	976|Bacteroidetes	PT	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
k59_291721_1	1123514.KB905899_gene1044	4.08e-48	154.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,4617D@72273|Thiotrichales	72273|Thiotrichales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_291721_2	1123518.ARWI01000001_gene242	2.88e-43	157.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1026307_1	411154.GFO_1492	1.25e-78	243.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_1026307_2	1121931.AUHG01000012_gene2672	3.54e-28	110.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1HWSR@117743|Flavobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_8939_1	946077.W5A_13081	6.37e-64	206.0	COG3547@1|root,COG3547@2|Bacteria,4NHKG@976|Bacteroidetes,1IJ01@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1760590_1	411154.GFO_0802	7.39e-121	358.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1760590_2	411154.GFO_0801	6.51e-125	358.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,1I2IW@117743|Flavobacteriia	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_574180_1	1355368.JART01000008_gene1752	1.1e-92	281.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2YRGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k59_179155_1	323850.Shew_2411	1.44e-64	216.0	COG0665@1|root,COG0665@2|Bacteria,1QVH0@1224|Proteobacteria,1T2DK@1236|Gammaproteobacteria,2QEV7@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_235729_1	929558.SMGD1_1799	8.84e-31	118.0	2BQX9@1|root,32JUG@2|Bacteria,1Q2H0@1224|Proteobacteria,42VPF@68525|delta/epsilon subdivisions,2YQMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_235729_2	563040.Saut_0545	2.8e-70	217.0	COG3166@1|root,COG3166@2|Bacteria,1Q1VC@1224|Proteobacteria,42UGS@68525|delta/epsilon subdivisions,2YPY1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_235729_3	1172190.M947_04580	3.88e-52	170.0	2AIHQ@1|root,318ZM@2|Bacteria,1Q19H@1224|Proteobacteria,42T48@68525|delta/epsilon subdivisions,2YPGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_65987_2	945713.IALB_0353	1.16e-85	259.0	COG0101@1|root,COG0101@2|Bacteria	2|Bacteria	J	tRNA pseudouridine synthase activity	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_1421216_2	362418.IW19_23625	2.14e-191	548.0	COG0457@1|root,COG0457@2|Bacteria,4NIWW@976|Bacteroidetes,1III9@117743|Flavobacteriia,2NVH7@237|Flavobacterium	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1421216_3	694427.Palpr_2529	0.0	1115.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,2325T@171551|Porphyromonadaceae	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1421216_4	1492737.FEM08_35540	1.22e-77	244.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1HWRF@117743|Flavobacteriia,2NU9G@237|Flavobacterium	976|Bacteroidetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_65998_1	317025.Tcr_1788	2.36e-11	62.8	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RRKD@1236|Gammaproteobacteria,463MW@72273|Thiotrichales	72273|Thiotrichales	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_65998_2	1168067.JAGP01000001_gene581	1.47e-56	181.0	COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,1S85W@1236|Gammaproteobacteria,461GM@72273|Thiotrichales	72273|Thiotrichales	K	NikR C terminal nickel binding domain	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
k59_65998_3	1168067.JAGP01000001_gene582	2.67e-42	145.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,462BY@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_630748_1	572480.Arnit_0458	1.18e-149	432.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_1760624_1	1123514.KB905899_gene1035	6.69e-56	180.0	COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,46131@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_1760624_2	90813.JQMT01000001_gene1020	1.13e-62	206.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_1703913_1	385682.AFSL01000040_gene215	7.48e-110	322.0	COG0657@1|root,COG0657@2|Bacteria,4NHDX@976|Bacteroidetes,2FP2B@200643|Bacteroidia,3XKIN@558415|Marinilabiliaceae	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
k59_1026336_1	1178825.ALIH01000013_gene523	0.0	917.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_349249_2	1123518.ARWI01000001_gene285	4.57e-05	44.7	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,461UP@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_802147_1	1121931.AUHG01000011_gene1853	4.74e-05	43.9	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1I2YC@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_802147_2	411154.GFO_2666	1.09e-88	265.0	COG0778@1|root,COG0778@2|Bacteria,4NF4K@976|Bacteroidetes,1I1DI@117743|Flavobacteriia	976|Bacteroidetes	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_349253_2	1121931.AUHG01000010_gene155	5.2e-52	181.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_67675_1	1121931.AUHG01000010_gene315	3.75e-89	270.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1HWNA@117743|Flavobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
k59_67675_2	1121931.AUHG01000010_gene316	2.24e-19	87.4	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HXZ5@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
k59_123646_1	1124780.ANNU01000032_gene1227	0.0	939.0	COG3540@1|root,COG4677@1|root,COG3540@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	pel	-	3.1.1.11,3.1.4.3,3.2.1.82	ko:K01051,ko:K01114,ko:K10297,ko:K18650	ko00040,ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00040,map00562,map00564,map00565,map01100,map01110,map02024,map04919	M00081	R01312,R02027,R02052,R02362,R03332,R07381	RC00017,RC00425,RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko02042,ko04121	-	GH28	-	Beta_helix,Big_3,Pectinesterase,Pkinase
k59_575923_1	1121931.AUHG01000010_gene33	9e-107	313.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1HWSY@117743|Flavobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_969974_1	709032.Sulku_1511	4.56e-24	108.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,43DAG@68525|delta/epsilon subdivisions,2YTHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9
k59_969974_2	944547.ABLL_1008	8.58e-16	75.9	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_632474_1	1121875.KB907547_gene3444	1.14e-48	172.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_632474_2	1122225.AULQ01000001_gene1510	4.33e-102	299.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_632474_3	1380600.AUYN01000001_gene2685	3.83e-300	835.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1365703_1	1178825.ALIH01000006_gene1425	2.82e-101	301.0	COG4667@1|root,COG4667@2|Bacteria,4NF0K@976|Bacteroidetes,1HX96@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_1535443_1	1348657.M622_05805	2.89e-47	154.0	COG3312@1|root,COG3312@2|Bacteria,1NDM1@1224|Proteobacteria,2VWW4@28216|Betaproteobacteria,2KXMC@206389|Rhodocyclales	206389|Rhodocyclales	C	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
k59_1535443_2	85643.Tmz1t_0209	1.03e-45	154.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,2KVA0@206389|Rhodocyclales	206389|Rhodocyclales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_914462_1	1123514.KB905901_gene177	9.35e-143	430.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,45ZMP@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_237545_1	103372.F4X6L8	2.47e-08	62.8	COG0584@1|root,KOG2258@2759|Eukaryota,38CP3@33154|Opisthokonta,3BF2P@33208|Metazoa,3CTQT@33213|Bilateria,41YWU@6656|Arthropoda,3SM7J@50557|Insecta,46KXH@7399|Hymenoptera	33208|Metazoa	C	Glycerophosphoryl diester phosphodiesterase family	GDE1	GO:0000902,GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006066,GO:0006576,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0008081,GO:0008150,GO:0008152,GO:0008889,GO:0009056,GO:0009308,GO:0009395,GO:0009653,GO:0009987,GO:0016020,GO:0016021,GO:0016042,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019637,GO:0022008,GO:0023052,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0034308,GO:0034641,GO:0042439,GO:0042578,GO:0044106,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0047395,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052689,GO:0065007,GO:0070291,GO:0071704,GO:0071840,GO:0071944,GO:0120036,GO:0120039,GO:1901564,GO:1901575,GO:1901615	3.1.4.44,3.1.4.46	ko:K01126,ko:K19179	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_1253207_1	105559.Nwat_2788	7.6e-81	243.0	29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,1S6VD@1236|Gammaproteobacteria,1X0VV@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_293515_1	313598.MED152_12449	3.4e-254	733.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,3VX00@52959|Polaribacter	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_306743_2	411154.GFO_1019	3.9e-51	165.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1I0DR@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_1203672_1	85643.Tmz1t_2371	1.35e-115	342.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VIFH@28216|Betaproteobacteria,2KX72@206389|Rhodocyclales	206389|Rhodocyclales	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_1203672_2	85643.Tmz1t_2372	8.92e-22	88.2	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2VTKI@28216|Betaproteobacteria,2KX5S@206389|Rhodocyclales	206389|Rhodocyclales	L	Very short patch repair endonuclease	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
k59_757582_1	411154.GFO_2567	9.07e-100	300.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1378594_1	1123514.KB905899_gene681	9.95e-83	256.0	COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,1RQ2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
k59_306758_1	563040.Saut_0631	4.53e-92	282.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_645757_1	323850.Shew_0441	6.07e-70	218.0	COG2030@1|root,COG2030@2|Bacteria,1RAAG@1224|Proteobacteria,1S1Z8@1236|Gammaproteobacteria,2Q9VZ@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
k59_1548110_1	655815.ZPR_3880	2.63e-80	266.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4PKAS@976|Bacteroidetes,1IJ5T@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_476638_1	641526.ADIWIN_0044	1.54e-58	201.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_476638_2	504487.JCM19302_1795	5.32e-45	154.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1HX8X@117743|Flavobacteriia	976|Bacteroidetes	E	Gscfa family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
k59_588679_1	1565129.JSFF01000009_gene1842	3.49e-140	414.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RYVY@1236|Gammaproteobacteria,2Q9T1@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1435415_1	1123035.ARLA01000028_gene2544	5.52e-150	427.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,4C4FK@83612|Psychroflexus	976|Bacteroidetes	L	DDE domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_871254_1	1565129.JSFF01000016_gene182	1.02e-149	425.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,2Q9RV@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_22941_1	929558.SMGD1_2076	1.71e-72	221.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2YPGE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Biopolymer transporter ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1607045_1	929558.SMGD1_0640	7.21e-132	391.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1493248_1	313595.P700755_001394	4.35e-93	279.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1HXEB@117743|Flavobacteriia,4C2HB@83612|Psychroflexus	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_645783_1	929558.SMGD1_2761	2.04e-24	99.0	COG0697@1|root,COG0697@2|Bacteria,1QA9R@1224|Proteobacteria,42RRA@68525|delta/epsilon subdivisions,2YRCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_645783_2	929558.SMGD1_2772	2e-37	135.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_815967_1	1250005.PHEL85_2119	3.41e-128	376.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,1HZ6T@117743|Flavobacteriia,3VW8G@52959|Polaribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
k59_815967_2	1347342.BN863_9430	3.29e-170	488.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,1HY2E@117743|Flavobacteriia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
k59_1718976_1	411154.GFO_3350	1.55e-111	340.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl endopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_1152583_1	1123514.KB905901_gene44	3.57e-51	177.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4608P@72273|Thiotrichales	72273|Thiotrichales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_194249_1	1565314.OA34_03365	2.39e-33	118.0	2E63D@1|root,32SZ8@2|Bacteria,1N3BN@1224|Proteobacteria,42WAA@68525|delta/epsilon subdivisions,2YQCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO	cowN	-	-	ko:K21694	-	-	-	-	ko00000	-	-	-	-
k59_194249_2	1249480.B649_07015	4.67e-07	50.4	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2YNN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cofactor biosynthesis protein NifE	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_645793_1	1123518.ARWI01000001_gene1041	6.81e-112	340.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,46061@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_927100_1	1237149.C900_02810	1.56e-106	314.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,47MSG@768503|Cytophagia	976|Bacteroidetes	F	reductase, small chain	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_250985_1	1123228.AUIH01000009_gene1986	1.15e-55	191.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XH69@135619|Oceanospirillales	135619|Oceanospirillales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1324631_1	1046627.BZARG_2386	1.97e-16	73.9	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes,1I21F@117743|Flavobacteriia	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_1324631_2	391587.KAOT1_01330	1.62e-89	281.0	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes,1HXED@117743|Flavobacteriia	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_757648_1	1168034.FH5T_20355	5.95e-73	241.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes	976|Bacteroidetes	E	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1152603_1	572480.Arnit_0595	2.33e-95	288.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42RAU@68525|delta/epsilon subdivisions,2YPYM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_476698_1	326297.Sama_3279	2.83e-08	54.3	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,2QAGE@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_476698_2	1565129.JSFF01000029_gene3025	1.96e-76	242.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,2Q9P5@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2699	PALP,Thr_dehydrat_C
k59_1040887_1	521674.Plim_0185	2.19e-06	48.9	COG0253@1|root,COG0253@2|Bacteria,2IYCH@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_1040887_2	316067.Geob_1398	2.69e-72	219.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2WNCU@28221|Deltaproteobacteria,43SHK@69541|Desulfuromonadales	28221|Deltaproteobacteria	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_1324634_1	865937.Gilli_3077	3.29e-21	100.0	COG1520@1|root,COG3391@1|root,COG3828@1|root,COG4932@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,COG3828@2|Bacteria,COG4932@2|Bacteria,4NK97@976|Bacteroidetes,1HYP5@117743|Flavobacteriia,2P7C8@244698|Gillisia	976|Bacteroidetes	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
k59_81194_1	1121931.AUHG01000015_gene1192	2.91e-109	335.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_1324644_1	983544.Lacal_0434	1.44e-105	308.0	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1HZF0@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
k59_1324644_2	504487.JCM19302_593	1.35e-31	111.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,1I55S@117743|Flavobacteriia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_81201_1	247639.MGP2080_04055	1.5e-50	171.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1JBYZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_1324646_1	504487.JCM19302_855	1.91e-110	323.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1HXY3@117743|Flavobacteriia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
k59_1324646_2	1380600.AUYN01000009_gene1809	3.18e-134	388.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1HX8P@117743|Flavobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
k59_476719_1	1444309.JAQG01000017_gene733	1.92e-11	63.9	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,26QSG@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyisobutyrate dehydrogenase	glxR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_476719_2	1121931.AUHG01000012_gene2598	7.85e-195	545.0	COG0604@1|root,COG0604@2|Bacteria,4NF73@976|Bacteroidetes,1HXX9@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k59_871338_1	929558.SMGD1_0307	4.51e-108	322.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2YMUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_1324666_1	945713.IALB_0771	1.29e-38	135.0	COG0712@1|root,COG0712@2|Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1324666_2	517418.Ctha_0873	9.27e-11	61.2	COG0056@1|root,COG0056@2|Bacteria,1FDND@1090|Chlorobi	1090|Chlorobi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1548222_1	1168065.DOK_02256	2.51e-84	273.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1J5FP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	lapB	-	-	ko:K11004,ko:K12541	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00330,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2,3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_1776144_1	1123514.KB905899_gene642	6.79e-136	387.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,461C3@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_588790_1	637910.ROD_08021	3.18e-42	154.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3WX33@544|Citrobacter	1236|Gammaproteobacteria	C	Iron-containing alcohol dehydrogenase	adhE	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199	Aldedh,Fe-ADH
k59_306884_1	1121931.AUHG01000011_gene1907	5.83e-119	356.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia	976|Bacteroidetes	T	gtp-binding protein typa	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_979567_1	323850.Shew_3065	5.32e-93	282.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,2Q97D@267890|Shewanellaceae	1236|Gammaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	visC	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_1495479_2	563040.Saut_0011	6.44e-35	124.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2YNXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1380682_1	1178825.ALIH01000005_gene310	2.31e-66	221.0	COG0110@1|root,COG2242@1|root,COG0110@2|Bacteria,COG2242@2|Bacteria,4NHX5@976|Bacteroidetes,1I0U6@117743|Flavobacteriia	976|Bacteroidetes	H	Acetyltransferase (Isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_1380682_2	865937.Gilli_1073	3.26e-78	244.0	COG1216@1|root,COG1216@2|Bacteria,4NP8J@976|Bacteroidetes,1IM73@117743|Flavobacteriia,2P7KD@244698|Gillisia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1380682_3	1178825.ALIH01000005_gene308	2.85e-126	367.0	COG1215@1|root,COG1215@2|Bacteria,4PKUN@976|Bacteroidetes,1IMP6@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1380682_4	1239415.CM001837_gene1917	1.81e-50	167.0	COG1216@1|root,COG1216@2|Bacteria,4NJMY@976|Bacteroidetes,1HYJN@117743|Flavobacteriia,37DIH@326319|Dokdonia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_253307_1	1121931.AUHG01000012_gene2543	1.29e-85	254.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_253307_2	411154.GFO_1636	1.29e-14	71.2	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k59_1154889_1	929562.Emtol_2235	2.09e-88	269.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47JBA@768503|Cytophagia	976|Bacteroidetes	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1098404_1	1380600.AUYN01000001_gene2342	4.33e-127	380.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
k59_138557_1	7029.ACYPI072288-PA	2.99e-14	75.5	2EJPP@1|root,2SPTN@2759|Eukaryota,3AKN6@33154|Opisthokonta,3BV37@33208|Metazoa,3DH1Y@33213|Bilateria,422J0@6656|Arthropoda,3SRB2@50557|Insecta	33208|Metazoa	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_364229_1	1123514.KB905899_gene1573	7.07e-68	206.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,460Q2@72273|Thiotrichales	1236|Gammaproteobacteria	K	nitrogen regulatory protein P-II	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
k59_364229_2	472759.Nhal_3280	6.02e-17	79.3	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWG6@135613|Chromatiales	135613|Chromatiales	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1437613_1	411154.GFO_3571	8.12e-90	265.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes,1I1BM@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
k59_1437613_2	1121931.AUHG01000010_gene600	2.01e-90	278.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_706125_1	563040.Saut_2139	1.91e-99	291.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2YMYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_929259_1	1266925.JHVX01000015_gene206	2.28e-93	303.0	COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,2VHZ8@28216|Betaproteobacteria,374G2@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
k59_138576_1	1565129.JSFF01000004_gene3246	4.33e-65	203.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,2Q921@267890|Shewanellaceae	1236|Gammaproteobacteria	O	SMART Prolyl 4-hydroxylase, alpha subunit	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_138576_2	458817.Shal_2442	4.4e-18	80.9	COG4929@1|root,COG4929@2|Bacteria,1MZW2@1224|Proteobacteria,1S96E@1236|Gammaproteobacteria,2QCMR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157,DUF4401,GDYXXLXY
k59_364257_2	1232410.KI421412_gene97	2.65e-58	196.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43SAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-70 factor, region 1.1	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_421851_1	323850.Shew_0872	1.81e-45	152.0	COG2966@1|root,COG2966@2|Bacteria,1NH2X@1224|Proteobacteria,1RN1Q@1236|Gammaproteobacteria,2Q960@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Putative threonine/serine exporter	yjjP	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071944	-	-	-	-	-	-	-	-	-	-	ThrE
k59_421851_2	323850.Shew_0873	6.78e-67	205.0	COG3610@1|root,COG3610@2|Bacteria,1RAWK@1224|Proteobacteria,1S2KX@1236|Gammaproteobacteria,2QBKC@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Threonine/Serine exporter, ThrE	yjjB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0010033,GO:0010243,GO:0015711,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901652,GO:1901698,GO:1901700	-	-	-	-	-	-	-	-	-	-	ThrE_2
k59_590895_2	1178825.ALIH01000007_gene1590	2.4e-109	321.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_590895_4	1178825.ALIH01000007_gene1588	4.69e-75	225.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_590895_5	1380600.AUYN01000009_gene967	1.06e-119	382.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_1778457_1	655815.ZPR_2462	3.17e-54	182.0	COG0668@1|root,COG0668@2|Bacteria,4NFX6@976|Bacteroidetes,1HWPR@117743|Flavobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_929280_2	929558.SMGD1_2289	2.39e-90	269.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,42T7W@68525|delta/epsilon subdivisions,2YPM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01205	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k59_929280_3	326298.Suden_1388	3.19e-38	139.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_1550364_1	1298880.AUEV01000002_gene1499	3.63e-16	81.3	COG0642@1|root,COG0745@1|root,COG1511@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2GKQX@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_364280_1	709032.Sulku_1541	6.41e-13	67.4	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_3
k59_364280_2	1232437.KL661972_gene4773	6.68e-13	67.0	COG2227@1|root,COG2227@2|Bacteria,1QZT3@1224|Proteobacteria,42QXG@68525|delta/epsilon subdivisions,2WMWI@28221|Deltaproteobacteria,2MJJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_873540_2	1121931.AUHG01000020_gene3124	1.69e-32	115.0	2CP87@1|root,32SIN@2|Bacteria,4NS9S@976|Bacteroidetes,1I5NE@117743|Flavobacteriia	976|Bacteroidetes	S	ribonuclease Z	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1495583_1	1121937.AUHJ01000020_gene1255	9.34e-46	167.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,465KJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_818281_2	1296415.JACC01000003_gene2976	7.18e-08	55.5	COG3093@1|root,COG3093@2|Bacteria,4NSDG@976|Bacteroidetes,1I3X0@117743|Flavobacteriia,2YJED@290174|Aquimarina	976|Bacteroidetes	K	Bacteriophage CI repressor helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Phage_CI_repr
k59_138618_1	143224.JQMD01000002_gene2438	4.81e-53	179.0	2EU5R@1|root,33MNC@2|Bacteria,4NYKD@976|Bacteroidetes,1I6YZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_981424_1	563040.Saut_2027	3.27e-112	337.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2YNS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COGs COG0025 NhaP-type Na H and K H antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
k59_364296_1	411154.GFO_1419	7.7e-82	254.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_929305_1	1123518.ARWI01000001_gene482	6.9e-69	211.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,462ED@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
k59_929305_2	1123518.ARWI01000001_gene481	1.64e-110	330.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,460BY@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_214016_3	983544.Lacal_1090	1.02e-215	598.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_101205_1	1296415.JACC01000001_gene3443	3.55e-39	137.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,1HXKF@117743|Flavobacteriia	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
k59_101205_2	388413.ALPR1_00665	3.18e-38	134.0	COG1672@1|root,COG1672@2|Bacteria,4NU5E@976|Bacteroidetes,47SH6@768503|Cytophagia	976|Bacteroidetes	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
k59_101205_3	983544.Lacal_2183	1.11e-19	87.8	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1682251_1	1123518.ARWI01000001_gene2359	5.13e-87	261.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYIQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1567836_1	326298.Suden_0584	5.35e-17	79.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,42P3X@68525|delta/epsilon subdivisions,2YN2A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_1567836_2	929558.SMGD1_1956	1.61e-135	396.0	COG3642@1|root,COG3642@2|Bacteria,1NSBH@1224|Proteobacteria,42Q7Z@68525|delta/epsilon subdivisions,2YN3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_496110_1	1121931.AUHG01000010_gene755	6.26e-152	450.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_944134_1	1121456.ATVA01000012_gene2810	2.08e-63	201.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2M8BZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM transferase hexapeptide repeat containing protein	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_944134_2	365046.Rta_10870	5.06e-51	172.0	COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,2WHKJ@28216|Betaproteobacteria,4AFQB@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_606589_2	985255.APHJ01000008_gene1850	7.13e-07	49.7	2BMYJ@1|root,32GIC@2|Bacteria,4PCHQ@976|Bacteroidetes,1ICU7@117743|Flavobacteriia,2P7K8@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_666049_1	497321.C664_17447	1.01e-139	396.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,2KWZJ@206389|Rhodocyclales	206389|Rhodocyclales	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
k59_724658_1	1123514.KB905901_gene57	8.94e-89	278.0	COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria,1SD6Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HD superfamily	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_1454635_1	1353528.DT23_10620	4.5e-51	177.0	COG0463@1|root,COG1215@1|root,COG0463@2|Bacteria,COG1215@2|Bacteria,1MU5I@1224|Proteobacteria,2U4NG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1398074_1	90814.KL370891_gene715	7.02e-74	233.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,460GT@72273|Thiotrichales	72273|Thiotrichales	N	SRP54-type protein, GTPase domain	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_1398074_2	1123514.KB905899_gene1418	9.15e-102	301.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,45ZS6@72273|Thiotrichales	72273|Thiotrichales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
k59_381822_1	572480.Arnit_1777	1.93e-101	298.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,42T0U@68525|delta/epsilon subdivisions,2YPN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_1116298_1	1415778.JQMM01000001_gene1498	2.56e-103	314.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,1J5EI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ACT domain	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
k59_496171_1	929558.SMGD1_1908	2.13e-138	410.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
k59_1345067_1	1168289.AJKI01000022_gene1862	1.11e-41	154.0	COG0286@1|root,COG0286@2|Bacteria,4NII0@976|Bacteroidetes	976|Bacteroidetes	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
k59_835010_1	387093.SUN_1332	4.02e-134	394.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42NYV@68525|delta/epsilon subdivisions,2YN1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_999179_1	1249480.B649_06845	2.94e-89	270.0	2BV3K@1|root,32QGM@2|Bacteria,1Q4NH@1224|Proteobacteria,42ZI1@68525|delta/epsilon subdivisions,2YRN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_999179_2	709032.Sulku_1547	3.63e-52	176.0	COG3864@1|root,COG3864@2|Bacteria,1Q995@1224|Proteobacteria,42YHV@68525|delta/epsilon subdivisions,2YRK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1286302_2	827.JFJK01000015_gene537	0.000409	46.2	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1454708_1	1250006.JHZZ01000001_gene1892	3.42e-65	199.0	COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes,1I2YN@117743|Flavobacteriia,3VWKQ@52959|Polaribacter	976|Bacteroidetes	K	Nitrogen regulatory protein P-II	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_326939_1	1380600.AUYN01000009_gene2000	4.46e-67	208.0	COG0513@1|root,COG0513@2|Bacteria,4NMA1@976|Bacteroidetes,1I2ZI@117743|Flavobacteriia	976|Bacteroidetes	JKL	RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD
k59_892981_1	641526.ADIWIN_2409	2.25e-135	403.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWZV@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Endonuclease_1,LTD
k59_1516411_1	572480.Arnit_2628	1.97e-97	296.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2YMY6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_668873_1	563040.Saut_0906	3.3e-114	343.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2YMKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_271815_1	90814.KL370891_gene1592	1.36e-93	295.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_1400478_1	1121912.AUHD01000005_gene1829	2.22e-92	277.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
k59_1400478_2	1178825.ALIH01000002_gene1026	1.31e-51	179.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_44164_1	1137281.D778_02492	4.36e-155	445.0	COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes,1HXM0@117743|Flavobacteriia	976|Bacteroidetes	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_329554_1	387093.SUN_0274	5.23e-67	211.0	COG0845@1|root,COG0845@2|Bacteria,1QE6S@1224|Proteobacteria,42QGG@68525|delta/epsilon subdivisions,2YNSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_329554_2	563040.Saut_1321	2.63e-19	86.7	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1570283_1	944547.ABLL_2668	3.93e-25	101.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2YNHM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_1570283_2	572480.Arnit_0007	5.09e-71	215.0	2ASWM@1|root,32ZGF@2|Bacteria,1ND0U@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3010
k59_893021_1	1121931.AUHG01000012_gene2881	2.58e-72	227.0	COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,1IJAV@117743|Flavobacteriia	976|Bacteroidetes	EGP	Nucleoside H symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
k59_893021_2	1121931.AUHG01000012_gene2882	2.06e-76	238.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,1HXIS@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_384548_1	1121935.AQXX01000139_gene3044	1.36e-49	164.0	COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,1RRAF@1236|Gammaproteobacteria,1XJEV@135619|Oceanospirillales	135619|Oceanospirillales	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
k59_1221173_1	1537917.JU82_07115	1.02e-134	409.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_44199_1	1121931.AUHG01000017_gene1467	1.92e-76	246.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_44199_2	1121931.AUHG01000017_gene1468	1.22e-57	186.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1HX36@117743|Flavobacteriia	976|Bacteroidetes	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1221197_1	572480.Arnit_0145	8.84e-32	121.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1221197_2	572480.Arnit_0146	2.47e-95	282.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,42ST2@68525|delta/epsilon subdivisions,2YPG7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_1516473_1	411154.GFO_0008	2.59e-112	334.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
k59_1457155_1	709032.Sulku_0538	9.59e-52	169.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42UAU@68525|delta/epsilon subdivisions,2YNG0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_216857_1	572480.Arnit_1934	6.9e-110	337.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_104117_1	563040.Saut_1480	5.3e-121	375.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_384609_1	1121931.AUHG01000010_gene453	8.31e-31	117.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HY65@117743|Flavobacteriia	976|Bacteroidetes	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_1742124_1	96561.Dole_0198	3.88e-35	130.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,2MNN7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	pcmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1400556_1	326298.Suden_0617	4.04e-202	588.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1400556_2	326298.Suden_0618	2.56e-09	57.4	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_1289069_1	1121904.ARBP01000001_gene5644	1.21e-225	650.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,47MVB@768503|Cytophagia	976|Bacteroidetes	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k59_104134_1	929558.SMGD1_0455	3.31e-84	259.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2YM9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_104134_2	326298.Suden_1463	8.03e-69	216.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2YMG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iIT341.HP1375	Acetyltransf_11,Hexapep
k59_1061655_1	411154.GFO_2208	7.96e-84	249.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_271939_1	1249480.B649_06360	2.66e-79	252.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1457221_2	1172190.M947_11455	2.41e-29	115.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2YMVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	phosphomannomutase	glmM_1	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1457221_3	1121887.AUDK01000001_gene543	2.48e-08	58.5	COG0642@1|root,COG0745@1|root,COG1879@1|root,COG0745@2|Bacteria,COG1879@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,2NUY8@237|Flavobacterium	976|Bacteroidetes	T	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Peripla_BP_4,Response_reg
k59_44291_1	1380600.AUYN01000009_gene1690	7.71e-114	343.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_158425_1	1304883.KI912532_gene2410	5.7e-55	189.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,2VHVK@28216|Betaproteobacteria,2KXAP@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
k59_1570422_1	572480.Arnit_2422	1.75e-86	265.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42PA7@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_1570422_2	572480.Arnit_2423	3.77e-05	45.1	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_1685358_1	1121931.AUHG01000018_gene1349	3.2e-93	278.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1HXCT@117743|Flavobacteriia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
k59_1061710_1	1453498.LG45_14035	5.08e-108	341.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1I0F2@117743|Flavobacteriia,2NVKY@237|Flavobacterium	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_609165_1	572480.Arnit_2255	1.9e-109	327.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2YN2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_1289140_1	1121931.AUHG01000018_gene1413	3.39e-116	352.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
k59_553304_1	867900.Celly_2201	2.01e-97	290.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,1HXQV@117743|Flavobacteriia,1F8G8@104264|Cellulophaga	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_1799083_1	926559.JoomaDRAFT_0760	3.75e-35	130.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_1400645_1	411154.GFO_2792	2.17e-61	188.0	COG3565@1|root,COG3565@2|Bacteria,4NNHW@976|Bacteroidetes,1I212@117743|Flavobacteriia	976|Bacteroidetes	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1400645_2	411154.GFO_2793	2.59e-36	131.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1HYV6@117743|Flavobacteriia	976|Bacteroidetes	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_441887_1	1123518.ARWI01000001_gene1914	2.21e-09	55.1	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,460KF@72273|Thiotrichales	72273|Thiotrichales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_441887_2	1123518.ARWI01000001_gene1915	4.62e-77	231.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,460TA@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_216986_1	316067.Geob_1590	5.66e-53	177.0	COG2770@1|root,COG2770@2|Bacteria,1NRS4@1224|Proteobacteria,42YW7@68525|delta/epsilon subdivisions,2WTW5@28221|Deltaproteobacteria,43TSJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP
k59_329746_1	1121931.AUHG01000020_gene3152	7.23e-86	268.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1HYHI@117743|Flavobacteriia	976|Bacteroidetes	J	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_893184_1	945713.IALB_0265	2.65e-32	120.0	COG4902@1|root,COG4902@2|Bacteria	2|Bacteria	-	-	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	DUF2202
k59_609194_1	572480.Arnit_0409	1.03e-38	134.0	COG4649@1|root,COG4649@2|Bacteria,1Q2HI@1224|Proteobacteria,42VQJ@68525|delta/epsilon subdivisions,2YQ7B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_609194_2	572480.Arnit_0410	1.31e-16	78.6	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_1570456_1	387092.NIS_1462	4.97e-53	182.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2YMRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1570456_2	929558.SMGD1_0638	7.59e-12	64.3	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2YT0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	tagE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_272002_1	1123279.ATUS01000001_gene1553	1.18e-46	178.0	COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,1RWWH@1236|Gammaproteobacteria,1J9I1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_396710_1	1565129.JSFF01000009_gene1742	3.73e-102	303.0	COG1776@1|root,COG2201@1|root,COG1776@2|Bacteria,COG2201@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,2QB0S@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM response regulator receiver	cheC	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1639412_1	90814.KL370891_gene1548	2.93e-28	110.0	2BW0Y@1|root,2ZI2P@2|Bacteria,1P7E3@1224|Proteobacteria,1SVW7@1236|Gammaproteobacteria,463C6@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1639412_2	717773.Thicy_0195	9.3e-76	240.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,45ZMX@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_396714_1	929558.SMGD1_0400	2.67e-44	163.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YRBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_9,dCache_3
k59_1413478_1	411154.GFO_2544	1.63e-58	186.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_1074150_1	929558.SMGD1_2349	2.44e-182	516.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_848175_1	1191299.AJYX01000042_gene2358	8.81e-25	103.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales	135623|Vibrionales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_792033_1	411154.GFO_0488	3.69e-152	440.0	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes,1HXED@117743|Flavobacteriia	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1526317_1	223926.28807127	7.29e-71	225.0	2AJUS@1|root,31AHF@2|Bacteria,1Q5NB@1224|Proteobacteria,1TFAU@1236|Gammaproteobacteria,1Y1W5@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1752372_1	76114.ebA38	3.92e-96	302.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria,2KV0R@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_566116_1	1178825.ALIH01000004_gene2844	2.26e-185	520.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1HXGU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1245087_1	1168034.FH5T_13230	3.77e-06	49.7	COG3940@1|root,COG3940@2|Bacteria,4PKWP@976|Bacteroidetes,2G06I@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
k59_1245087_2	1034769.KB910518_gene948	1.18e-184	546.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,26QZH@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
k59_567696_1	572480.Arnit_2528	4.73e-36	140.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42T9J@68525|delta/epsilon subdivisions,2YRPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_906801_1	323850.Shew_1865	9.03e-56	191.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,2QAM0@267890|Shewanellaceae	1236|Gammaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_1641267_1	713587.THITH_07400	2.06e-15	75.5	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1WY34@135613|Chromatiales	135613|Chromatiales	S	pfam ammecr1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_1641267_2	317025.Tcr_1133	2.78e-22	95.5	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,1T2MP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1471067_1	411154.GFO_0212	3.68e-73	240.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1471067_2	1121931.AUHG01000010_gene863	9.97e-25	99.4	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1HXE0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_963084_1	360106.CFF8240_1450	3.77e-76	244.0	COG2857@1|root,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_1697547_1	1137281.D778_01003	1.3e-82	249.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,1I1W6@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
k59_1697547_2	1137281.D778_01002	3.76e-33	116.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_398446_1	1123518.ARWI01000001_gene964	3.88e-86	273.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_398446_2	90814.KL370891_gene307	9.08e-79	241.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,4604S@72273|Thiotrichales	72273|Thiotrichales	J	glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_1415139_2	944547.ABLL_1616	1.76e-17	82.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42N49@68525|delta/epsilon subdivisions,2YND2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
k59_680977_1	1453500.AT05_01150	4.02e-111	345.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_455027_1	313590.MED134_11471	1.41e-16	77.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia,37EH1@326319|Dokdonia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_455027_2	1380600.AUYN01000009_gene972	3.4e-184	533.0	COG0810@1|root,COG0810@2|Bacteria,4PKAV@976|Bacteroidetes,1HWXW@117743|Flavobacteriia	976|Bacteroidetes	M	Gliding motility protein RemB	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_172577_1	565045.NOR51B_1736	5.57e-58	207.0	COG0642@1|root,COG0834@1|root,COG4251@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,1JC2G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_1415143_1	1380600.AUYN01000007_gene3127	3.32e-157	476.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_1415143_2	1347342.BN863_35360	1.08e-68	221.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1358144_1	411154.GFO_0276	4.41e-33	121.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia	976|Bacteroidetes	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_1358144_2	1121931.AUHG01000018_gene1407	6.64e-47	161.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_229032_1	1380600.AUYN01000006_gene273	1.08e-26	106.0	COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,1HZWT@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_229032_2	1178825.ALIH01000013_gene518	3.58e-06	48.5	COG2067@1|root,COG2067@2|Bacteria,4PFMQ@976|Bacteroidetes,1HYJE@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_398490_1	1123518.ARWI01000001_gene757	3.11e-100	296.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,460FK@72273|Thiotrichales	72273|Thiotrichales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_398490_2	1123518.ARWI01000001_gene756	6.64e-33	122.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,45ZRK@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1697599_1	1123514.KB905901_gene121	4.02e-60	199.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,1RN0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_1697599_2	90814.KL370891_gene1689	5.94e-78	235.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,460TI@72273|Thiotrichales	72273|Thiotrichales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_1358168_1	497321.C664_14134	3.55e-55	187.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,2VJFD@28216|Betaproteobacteria,2KUYC@206389|Rhodocyclales	206389|Rhodocyclales	P	ferric reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
k59_115993_1	1121931.AUHG01000011_gene2424	3.06e-48	161.0	COG1216@1|root,COG1216@2|Bacteria,4NRKJ@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glyco_transf_7C
k59_115993_2	1250278.JQNQ01000001_gene701	3.13e-74	228.0	COG3403@1|root,COG3403@2|Bacteria,4NH39@976|Bacteroidetes,1HZXP@117743|Flavobacteriia	976|Bacteroidetes	S	YqcI/YcgG family	-	-	-	ko:K09190	-	-	-	-	ko00000	-	-	-	YqcI_YcgG
k59_1415173_1	1121912.AUHD01000001_gene2309	3.15e-216	602.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1415173_2	1122225.AULQ01000004_gene2101	9.96e-115	337.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_455103_2	1476902.A0A097P6S4_9CAUD	1.12e-226	661.0	4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses  no RNA stage,4QPBY@28883|Caudovirales,4QHYN@10662|Myoviridae	10662|Myoviridae	S	amidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_681053_1	504487.JCM19302_3107	1.54e-25	98.2	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_681053_2	1380600.AUYN01000009_gene1789	5.71e-115	332.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1HZ9W@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
k59_681053_3	1178825.ALIH01000008_gene700	9.4e-133	383.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1HXPT@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_681053_4	1380600.AUYN01000009_gene1787	1.13e-78	239.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1HXNW@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_963173_1	1123326.JFBL01000009_gene814	5.1e-22	95.1	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,42Q4E@68525|delta/epsilon subdivisions,2YR1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_963173_2	572480.Arnit_1284	6.97e-52	167.0	COG4665@1|root,COG4665@2|Bacteria,1QYCM@1224|Proteobacteria,43BD0@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_1358202_1	1443111.JASG01000004_gene2253	1.61e-44	153.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2TQT6@28211|Alphaproteobacteria,3ZWXB@60136|Sulfitobacter	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	nrtB	-	-	ko:K02050,ko:K15577	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	BPD_transp_1
k59_1358202_2	1123366.TH3_20678	2.83e-124	367.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,2JRE4@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051,ko:K15576	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
k59_398551_1	1380600.AUYN01000007_gene3276	2.33e-66	204.0	2AGNU@1|root,316WB@2|Bacteria,4NSNZ@976|Bacteroidetes,1I2U3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_398551_2	1380600.AUYN01000007_gene3278	1.59e-78	241.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1132772_1	1123518.ARWI01000001_gene2391	4.72e-131	399.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales	72273|Thiotrichales	M	PFAM AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k59_1132772_2	1123514.KB905899_gene1165	6.03e-119	345.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,460NJ@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_455127_1	1280673.AUJJ01000023_gene3136	6.18e-11	67.4	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,4BYQG@830|Butyrivibrio	186801|Clostridia	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
k59_567799_1	411154.GFO_1537	4.66e-151	446.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_285520_2	926559.JoomaDRAFT_3295	6.38e-39	136.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
k59_849711_1	944546.ABED_1188	9.61e-32	128.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_624498_1	1172190.M947_10595	6.55e-249	704.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_1245208_1	1172190.M947_04205	1.94e-118	353.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_285524_1	563040.Saut_1128	1.92e-35	122.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_285524_3	1249480.B649_05850	2.19e-51	166.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2YPCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k59_1528057_1	90814.KL370891_gene1862	2.32e-09	57.4	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,46038@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1528057_2	1123518.ARWI01000001_gene1778	1.08e-62	197.0	COG2197@1|root,COG2197@2|Bacteria,1RDUR@1224|Proteobacteria,1S9GG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1528057_3	1278307.KB906969_gene2215	8.64e-29	112.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	-	-	-	-	-	-	-	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_1528067_1	1178825.ALIH01000001_gene2538	6.48e-60	195.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1HY15@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
k59_1528067_2	402612.FP1386	1.2e-13	67.8	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia,2NW0I@237|Flavobacterium	976|Bacteroidetes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_229163_1	1123518.ARWI01000001_gene1044	2.47e-45	164.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_229163_2	1123518.ARWI01000001_gene1043	4e-11	59.3	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,460JT@72273|Thiotrichales	72273|Thiotrichales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_1358231_1	1380600.AUYN01000006_gene503	1.16e-195	545.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1HXKI@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1358231_2	1202532.FF52_13531	3.48e-121	377.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia,2NTII@237|Flavobacterium	976|Bacteroidetes	E	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
k59_793944_1	717774.Marme_0458	6.8e-88	277.0	COG0737@1|root,COG0737@2|Bacteria,1MU11@1224|Proteobacteria,1RMQV@1236|Gammaproteobacteria,1XID2@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_1415244_1	1123228.AUIH01000004_gene1130	1.26e-83	259.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XI17@135619|Oceanospirillales	135619|Oceanospirillales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_1754288_1	398720.MED217_15435	6.31e-06	47.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia,2XHZX@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_1754288_2	1484460.JSWG01000001_gene2223	3.12e-73	225.0	COG0457@1|root,COG0457@2|Bacteria,4NNWA@976|Bacteroidetes,1I350@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1697688_1	1123514.KB905899_gene1055	2.19e-49	175.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales	72273|Thiotrichales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_906960_1	1123228.AUIH01000006_gene2186	7.47e-17	76.6	2CJUR@1|root,30ZA2@2|Bacteria,1REPK@1224|Proteobacteria,1S4N7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1471268_1	1121007.AUML01000024_gene335	1.5e-156	450.0	COG0438@1|root,COG0438@2|Bacteria,4NGDA@976|Bacteroidetes,1HY6S@117743|Flavobacteriia,2YH0V@290174|Aquimarina	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_1302581_1	400668.Mmwyl1_2050	4.7e-52	185.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHSH@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_1132821_1	1484460.JSWG01000011_gene1725	3.16e-107	316.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1HXFJ@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
k59_1132821_2	1286632.P278_17790	4.44e-147	419.0	COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,1HY1H@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_567850_1	562970.Btus_2082	2.39e-39	146.0	COG0365@1|root,COG0365@2|Bacteria,1VQZF@1239|Firmicutes,4HTSG@91061|Bacilli,279KV@186823|Alicyclobacillaceae	91061|Bacilli	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_1584855_1	1121931.AUHG01000011_gene1820	4.57e-104	314.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
k59_793980_1	980584.AFPB01000153_gene365	2.43e-59	203.0	COG5434@1|root,COG5434@2|Bacteria,4NKHU@976|Bacteroidetes,1I0UA@117743|Flavobacteriia	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_1075662_1	572480.Arnit_1471	1.25e-28	111.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2YN3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1075662_2	572480.Arnit_1472	5.04e-29	104.0	COG1722@1|root,COG1722@2|Bacteria,1Q35M@1224|Proteobacteria,42WTB@68525|delta/epsilon subdivisions,2YQRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k59_297733_2	118005.AWNK01000007_gene599	5.72e-06	47.4	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k59_807884_2	1392490.JHZX01000001_gene2775	1.87e-58	185.0	COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,1I2BV@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1599044_2	1005999.GLGR_0408	7.78e-16	76.3	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_15816_1	563040.Saut_1523	8.72e-17	78.6	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YMUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_15816_2	563040.Saut_1524	3.4e-60	198.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2YMVM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_1033397_1	273121.WS0853	7.06e-20	86.3	COG0745@1|root,COG0745@2|Bacteria,1NW7Q@1224|Proteobacteria,42S6J@68525|delta/epsilon subdivisions,2YPCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1033397_2	929558.SMGD1_1736	1.23e-21	95.5	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1QZ25@1224|Proteobacteria,43CEB@68525|delta/epsilon subdivisions,2YRHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_863805_1	1121875.KB907549_gene1742	1.26e-65	209.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1I19C@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_863805_2	1123393.KB891333_gene2644	1.3e-62	201.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,2VQGW@28216|Betaproteobacteria,1KSP9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_863805_3	1121875.KB907546_gene2242	5.74e-28	104.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes,1I1CJ@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
k59_863805_4	616991.JPOO01000003_gene2306	1.64e-31	114.0	COG5502@1|root,COG5502@2|Bacteria,4NN8N@976|Bacteroidetes,1I1CJ@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
k59_863805_5	1250232.JQNJ01000001_gene2825	1.43e-276	773.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_863805_6	504487.JCM19302_1606	1.24e-133	386.0	COG0589@1|root,COG0589@2|Bacteria,4NGD6@976|Bacteroidetes,1HYDX@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein UspA and related nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_863805_7	1137281.D778_02231	4.36e-128	372.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_863805_8	1296415.JACC01000038_gene1882	1.43e-10	63.2	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia,2YJ0U@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1316815_1	1117315.AHCA01000003_gene20	7.6e-83	251.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,1RQ2V@1236|Gammaproteobacteria,2Q08P@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
k59_469118_1	1392490.JHZX01000001_gene1532	4.39e-53	170.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,1I2N1@117743|Flavobacteriia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_469118_2	1137281.D778_01642	7.18e-227	638.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_1033410_1	1122225.AULQ01000006_gene1034	1.29e-70	234.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_524913_1	1123514.KB905899_gene942	3.15e-221	629.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,45ZZJ@72273|Thiotrichales	72273|Thiotrichales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_524913_2	90814.KL370891_gene1143	3.52e-11	62.8	COG0835@1|root,COG3437@1|root,COG0835@2|Bacteria,COG3437@2|Bacteria,1RD7I@1224|Proteobacteria,1SKFD@1236|Gammaproteobacteria,46261@72273|Thiotrichales	72273|Thiotrichales	T	Two component signalling adaptor domain	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1711611_1	411154.GFO_0523	3.31e-132	377.0	COG0739@1|root,COG0739@2|Bacteria,4NN4Q@976|Bacteroidetes,1I1CW@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1599064_1	1380600.AUYN01000007_gene3238	5.3e-93	300.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1316829_1	572480.Arnit_1349	2.25e-67	219.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2YP81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_129319_1	572480.Arnit_0271	3.65e-15	75.9	COG3864@1|root,COG3864@2|Bacteria,1Q995@1224|Proteobacteria,42YHV@68525|delta/epsilon subdivisions,2YRK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_129319_2	1249480.B649_06870	6.53e-31	118.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42VWM@68525|delta/epsilon subdivisions,2YQKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0714 MoxR-like	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_1768324_2	1168067.JAGP01000001_gene255	1.15e-65	200.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,460QJ@72273|Thiotrichales	72273|Thiotrichales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_1768324_3	90814.KL370891_gene234	1.22e-132	378.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,4606F@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_1768324_4	1123518.ARWI01000001_gene1037	4.57e-64	200.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,460DP@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_1485586_1	391603.FBALC1_01857	3.74e-65	209.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1HXVZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1485586_2	1178825.ALIH01000001_gene2397	6.93e-132	376.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_299275_1	411154.GFO_0726	1.45e-69	221.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HX4B@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_186821_2	504487.JCM19302_2277	4.73e-151	429.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k59_524927_1	90814.KL370891_gene1539	1.55e-84	261.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales	72273|Thiotrichales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_524927_2	1123514.KB905899_gene537	2.34e-153	437.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,460HI@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_638442_1	930169.B5T_02704	2.23e-24	100.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1XHMV@135619|Oceanospirillales	135619|Oceanospirillales	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_638442_2	1121935.AQXX01000122_gene5651	4.41e-27	105.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1XI46@135619|Oceanospirillales	135619|Oceanospirillales	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_1033438_1	365046.Rta_10890	2.18e-38	147.0	COG3307@1|root,COG3307@2|Bacteria,1RK09@1224|Proteobacteria,2VT4W@28216|Betaproteobacteria,4AEHM@80864|Comamonadaceae	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_129334_1	1123518.ARWI01000001_gene1220	5.4e-05	47.8	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,45ZPS@72273|Thiotrichales	72273|Thiotrichales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_129334_2	1163617.SCD_n02137	1.41e-07	53.5	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria	1224|Proteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,GlcNAc_2-epim,Thioredox_DsbH
k59_15855_1	1380600.AUYN01000009_gene2019	3.56e-83	251.0	28JHY@1|root,2Z9BE@2|Bacteria,4NGKG@976|Bacteroidetes,1I1EX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1599084_1	1178825.ALIH01000001_gene2557	5.87e-105	328.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_1599084_2	983544.Lacal_1498	8.87e-94	283.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1HX81@117743|Flavobacteriia	976|Bacteroidetes	I	synthase	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_243288_1	1178825.ALIH01000001_gene2534	1.18e-99	295.0	COG2197@1|root,COG2197@2|Bacteria,4NR5M@976|Bacteroidetes,1HYNZ@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
k59_1711637_1	1416760.AYMS01000003_gene688	1.19e-33	124.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia,47GZU@76831|Myroides	976|Bacteroidetes	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_1711637_2	1380600.AUYN01000009_gene1738	2.7e-295	808.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1541000_1	411154.GFO_2954	1.85e-108	314.0	COG4083@1|root,30PDV@2|Bacteria,4PQ18@976|Bacteroidetes,1IKYB@117743|Flavobacteriia	976|Bacteroidetes	S	Exosortase	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
k59_638470_1	1123518.ARWI01000001_gene1906	4.28e-154	453.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_919960_1	1492737.FEM08_17310	3.49e-106	326.0	COG1653@1|root,COG1653@2|Bacteria,4NG6U@976|Bacteroidetes	976|Bacteroidetes	G	Pfam Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_919960_2	1347393.HG726019_gene8129	1.69e-06	51.6	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,2FMH6@200643|Bacteroidia,4ANFX@815|Bacteroidaceae	976|Bacteroidetes	P	COG COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
k59_1768363_1	1178825.ALIH01000007_gene1591	2.67e-130	389.0	COG0810@1|root,COG0810@2|Bacteria,4PKAV@976|Bacteroidetes,1HWXW@117743|Flavobacteriia	976|Bacteroidetes	M	Gliding motility protein RemB	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_581731_1	411154.GFO_3514	1.52e-65	200.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_581731_2	411154.GFO_3512	7.12e-52	172.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1599099_1	90814.KL370891_gene1555	4.72e-79	242.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,45ZW9@72273|Thiotrichales	72273|Thiotrichales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_1599099_2	90814.KL370891_gene1554	1.05e-186	520.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,45ZPG@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_1599099_3	1123518.ARWI01000001_gene2103	1.08e-09	56.2	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363	1.5.1.3	ko:K00287,ko:K18590	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020	DHFR_1
k59_73744_1	90813.JQMT01000001_gene172	2.15e-233	643.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4604G@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_73744_2	317025.Tcr_0246	1.1e-260	717.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,45ZW0@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_73744_3	90814.KL370891_gene175	2.77e-28	112.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,45ZW2@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1371417_1	411154.GFO_0584	3.73e-67	214.0	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes,1HWZH@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_412265_1	948106.AWZT01000067_gene2475	7.98e-42	156.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF,GAF_2,GGDEF,HAMP,PAS_4,PAS_9,Response_reg
k59_1655219_1	1121931.AUHG01000012_gene2923	3.23e-64	202.0	2B7X4@1|root,32143@2|Bacteria,4NNUI@976|Bacteroidetes,1I2MC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_1655219_2	411154.GFO_0983	3.31e-49	164.0	28MTA@1|root,2ZB1I@2|Bacteria,4NHGY@976|Bacteroidetes,1I14G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_524978_1	1366050.N234_36085	8.32e-221	614.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32
k59_1088918_1	362418.IW19_22040	2.53e-109	327.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia,2NUVR@237|Flavobacterium	976|Bacteroidetes	G	Pfam Major Facilitator Superfamily	gluP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1541022_1	1123514.KB905899_gene1458	1.64e-223	639.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,460M4@72273|Thiotrichales	72273|Thiotrichales	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1541022_2	90814.KL370891_gene670	8.56e-49	161.0	COG3951@1|root,COG3951@2|Bacteria,1QUV5@1224|Proteobacteria,1T224@1236|Gammaproteobacteria,461FV@72273|Thiotrichales	72273|Thiotrichales	MNO	Rod binding protein	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Rod-binding
k59_1541022_3	1123518.ARWI01000001_gene638	4.06e-54	179.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,4609R@72273|Thiotrichales	72273|Thiotrichales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_412268_1	1168067.JAGP01000001_gene177	9.93e-30	117.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,4604M@72273|Thiotrichales	72273|Thiotrichales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_412268_2	1123518.ARWI01000001_gene1161	1.68e-24	101.0	COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_73773_1	929558.SMGD1_2212	4.17e-93	298.0	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1198303_1	387093.SUN_0467	7.8e-26	107.0	COG0642@1|root,COG2205@2|Bacteria,1QZF7@1224|Proteobacteria,43CIH@68525|delta/epsilon subdivisions,2YTD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_695642_1	1122225.AULQ01000002_gene546	1.67e-86	267.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
k59_695642_2	1121887.AUDK01000024_gene1092	9.64e-106	314.0	COG4099@1|root,COG4099@2|Bacteria,4NIDF@976|Bacteroidetes,1I48B@117743|Flavobacteriia,2NXTN@237|Flavobacterium	976|Bacteroidetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Peptidase_S9
k59_695642_3	946077.W5A_07497	1.48e-56	195.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_1485680_1	944547.ABLL_2797	1.95e-64	206.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2YNH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_3
k59_1485680_2	709032.Sulku_1540	3.46e-64	208.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_412288_1	1392490.JHZX01000001_gene2754	2.04e-224	630.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia	976|Bacteroidetes	G	COG2211 Na melibiose symporter and related	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
k59_1428485_1	504487.JCM19302_1506	1.75e-144	413.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the FBPase class 1 family	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_243376_1	1173024.KI912149_gene5528	3.76e-29	119.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1316938_1	1137281.D778_01323	6.04e-305	837.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_412303_1	1380600.AUYN01000001_gene2778	9.59e-209	582.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1428501_1	313596.RB2501_13489	9.37e-56	197.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
k59_525033_1	411154.GFO_1451	2.93e-81	244.0	2CEU1@1|root,32S0H@2|Bacteria,4NM9W@976|Bacteroidetes,1I2DG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1259089_1	1123518.ARWI01000001_gene1258	3.67e-97	283.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,460ZP@72273|Thiotrichales	72273|Thiotrichales	H	Molybdenum cofactor biosynthesis protein MoaE	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_1259089_2	90814.KL370891_gene48	4.64e-65	210.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales	72273|Thiotrichales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_808051_1	357804.Ping_1245	1.66e-14	81.3	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2QHYE@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1198332_1	314254.OA2633_06134	6.28e-09	60.1	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2TVPG@28211|Alphaproteobacteria,43XR6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Eukaryotic-type carbonic anhydrase	acaP	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_1198332_2	90814.KL370891_gene1454	1.09e-94	284.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,45ZV3@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
k59_1657182_1	1358423.N180_08085	3.95e-13	66.2	2CFVU@1|root,3373K@2|Bacteria,4NWJS@976|Bacteroidetes,1J166@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1657182_2	1380600.AUYN01000006_gene545	1.59e-72	232.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_648725_1	360910.BAV0589	1.47e-37	138.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T5E8@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k59_760619_1	1380600.AUYN01000002_gene3	3.09e-128	410.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_1665527_1	411154.GFO_3376	1.38e-102	326.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1496311_2	1442598.JABW01000030_gene1383	2.89e-71	232.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2YTG8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k59_1551062_2	1424334.W822_05090	5.39e-37	136.0	COG5340@1|root,COG5340@2|Bacteria,1PZ9P@1224|Proteobacteria,2W3HU@28216|Betaproteobacteria,3T5K5@506|Alcaligenaceae	28216|Betaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1381453_1	531844.FIC_01888	4.61e-107	316.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia,405UN@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_1381453_2	1250005.PHEL85_2119	5.13e-87	268.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,1HZ6T@117743|Flavobacteriia,3VW8G@52959|Polaribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
k59_648763_1	1123514.KB905899_gene915	1.67e-106	317.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,460Y9@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_139317_1	1123518.ARWI01000001_gene1044	1.9e-267	773.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_982160_1	1120931.KB893936_gene77	1.48e-16	80.1	COG1925@1|root,COG4668@1|root,COG1925@2|Bacteria,COG4668@2|Bacteria,1MVP6@1224|Proteobacteria,1RQP4@1236|Gammaproteobacteria,1Y7A0@135625|Pasteurellales	135625|Pasteurellales	G	Bifunctional PTS system fructose-specific transporter subunit IIA HPr protein	fruB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS-HPr,PTS_EIIA_2
k59_982160_2	1280001.BAOA01000075_gene3218	4.73e-12	65.5	COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,1RNR1@1236|Gammaproteobacteria,1XT6Y@135623|Vibrionales	135623|Vibrionales	K	COG1609 Transcriptional regulators	fruR	-	-	ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4
k59_1551083_1	1123518.ARWI01000001_gene733	1.17e-24	99.8	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,460NI@72273|Thiotrichales	72273|Thiotrichales	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1551083_2	1123518.ARWI01000001_gene732	5.09e-111	326.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,4602K@72273|Thiotrichales	72273|Thiotrichales	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_707019_1	509635.N824_22320	1.48e-23	100.0	COG0463@1|root,COG0463@2|Bacteria,4NGHG@976|Bacteroidetes,1IUC2@117747|Sphingobacteriia	976|Bacteroidetes	M	Core-2/I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
k59_1043802_1	391587.KAOT1_04887	3.97e-45	164.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_8
k59_760669_1	709032.Sulku_1261	8.21e-86	258.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,42S32@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K02483,ko:K07659,ko:K07662	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00445,M00447,M00727,M00728,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1496361_1	326298.Suden_1827	1.99e-123	356.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2YN6R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_1496362_1	1232410.KI421413_gene713	1.93e-19	85.9	2DE9Y@1|root,2ZM4N@2|Bacteria,1Q17X@1224|Proteobacteria,43756@68525|delta/epsilon subdivisions,2X21C@28221|Deltaproteobacteria,43SFZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1496362_2	1232410.KI421413_gene712	4.35e-46	158.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43SUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt-1	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_1327714_1	323850.Shew_2962	3.33e-138	405.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,2QB1I@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the malic enzymes family	maeA	GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0004473,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006094,GO:0006108,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019318,GO:0019319,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0055114,GO:0071704,GO:1901576	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E1742	Malic_M,malic
k59_1043822_1	926559.JoomaDRAFT_1804	9.79e-136	416.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_84165_1	1121931.AUHG01000010_gene396	6.24e-164	473.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1438423_1	745718.JADT01000027_gene2522	3.34e-40	144.0	COG2356@1|root,COG2356@2|Bacteria,4PNZR@976|Bacteroidetes,1I4KS@117743|Flavobacteriia	976|Bacteroidetes	L	Carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
k59_422662_1	314287.GB2207_10943	3.04e-111	325.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1J4QY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the KdsA family	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_1099279_1	317025.Tcr_2002	3e-86	263.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,460DJ@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_309865_1	1565129.JSFF01000022_gene1396	2.81e-11	57.8	2BQF9@1|root,32JAP@2|Bacteria,1QEUF@1224|Proteobacteria,1TBQV@1236|Gammaproteobacteria,2QD2A@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_982250_1	326298.Suden_1510	1.04e-111	332.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_1438461_1	1286632.P278_11980	8.37e-187	564.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_422700_1	317025.Tcr_1214	3.1e-162	467.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_84223_1	367737.Abu_0743	1.12e-28	122.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k59_1779315_2	1172190.M947_02500	1.09e-71	223.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2YMHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k59_982279_2	572480.Arnit_2451	4.32e-46	154.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1269499_1	929556.Solca_0262	1.38e-16	85.1	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IVHM@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1496456_2	945713.IALB_0268	2.75e-15	75.1	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	pagN	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	Alginate_exp,OMP_b-brl,Surface_Ag_2
k59_982301_1	1008457.BAEX01000073_gene116	0.000137	43.5	2DM7Y@1|root,3247U@2|Bacteria,4NQ68@976|Bacteroidetes,1I3EP@117743|Flavobacteriia	976|Bacteroidetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k59_1722116_1	1123518.ARWI01000001_gene1734	2.59e-143	418.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,46079@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1722116_2	90814.KL370891_gene1905	5.65e-14	71.2	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,45ZSS@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_1043944_1	1123326.JFBL01000006_gene1045	7.32e-09	61.6	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
k59_254330_1	1298593.TOL_2705	4.28e-147	426.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XHAE@135619|Oceanospirillales	135619|Oceanospirillales	J	beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_254338_1	1178825.ALIH01000001_gene2386	2.28e-120	358.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_760818_1	1122225.AULQ01000005_gene2620	2.14e-88	266.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1HWP6@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_760818_2	1380600.AUYN01000007_gene3317	8.23e-217	602.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_874465_1	1121931.AUHG01000010_gene242	6.94e-119	345.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1HX5K@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
k59_874465_2	1121931.AUHG01000010_gene243	2.02e-09	57.4	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,4NDVW@976|Bacteroidetes,1HXBF@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome C biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_1155953_1	1123228.AUIH01000001_gene1334	8.61e-132	390.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XHWC@135619|Oceanospirillales	135619|Oceanospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1496533_1	1178825.ALIH01000005_gene189	3.79e-58	191.0	COG1835@1|root,COG1835@2|Bacteria,4PKKX@976|Bacteroidetes,1IJC6@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
k59_1496533_3	641526.ADIWIN_0717	3.42e-21	91.7	2E78C@1|root,331S1@2|Bacteria,4NPWT@976|Bacteroidetes,1I2MW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1496533_4	1168289.AJKI01000004_gene2955	8.66e-50	178.0	COG0515@1|root,COG5295@1|root,COG0515@2|Bacteria,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,2FYT9@200643|Bacteroidia	976|Bacteroidetes	UW	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_1099422_1	411154.GFO_1042	2.92e-225	632.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,1HY70@117743|Flavobacteriia	976|Bacteroidetes	G	COG3387 Glucoamylase and related glycosyl	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
k59_1381679_1	1121931.AUHG01000011_gene1974	2.08e-05	45.8	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Biotin_lipoyl,Na_Ala_symp,SprB
k59_1381679_2	1121931.AUHG01000011_gene1975	5e-74	231.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1HX4K@117743|Flavobacteriia	976|Bacteroidetes	L	COG1555 DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
k59_874495_1	436308.Nmar_0066	3.04e-66	213.0	COG1467@1|root,arCOG04110@2157|Archaea,41SCB@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
k59_1779444_1	118005.AWNK01000001_gene1996	1.09e-15	80.9	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19,TPR_2,TPR_8
k59_139551_1	317025.Tcr_1021	1.56e-69	219.0	COG2199@1|root,COG2199@2|Bacteria,1R4XN@1224|Proteobacteria,1RQ6S@1236|Gammaproteobacteria,461US@72273|Thiotrichales	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
k59_310020_1	633148.Tagg_1290	3.63e-05	50.8	COG0863@1|root,arCOG00129@2157|Archaea,2XPT8@28889|Crenarchaeota	28889|Crenarchaeota	L	DNA methylase N-4 N-6 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
k59_1551322_1	748247.AZKH_1408	9.85e-108	323.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria,2KVWE@206389|Rhodocyclales	206389|Rhodocyclales	L	impB/mucB/samB family	rumB	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
k59_874502_1	1323663.AROI01000024_gene1561	1.08e-22	103.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2
k59_1610464_1	1131553.JIBI01000060_gene706	2.8e-78	247.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,372FQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1610464_2	1207063.P24_11210	3.55e-20	88.2	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,2JU2U@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_197462_1	1123514.KB905899_gene490	7.43e-158	463.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,45ZTE@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_139561_1	62928.azo3852	2.03e-72	239.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,2KUPP@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1551336_1	411154.GFO_1659	2.02e-74	234.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia	976|Bacteroidetes	IQ	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
k59_310049_1	1304888.ATWF01000001_gene2325	1.74e-47	173.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,2GGBB@200930|Deferribacteres	200930|Deferribacteres	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1099480_1	251221.35212392	4.09e-08	58.5	COG4977@1|root,COG4977@2|Bacteria,1GFED@1117|Cyanobacteria	1117|Cyanobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_649046_1	1197477.IA57_00520	2.56e-84	259.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_1722260_1	627192.SLG_37450	3.81e-42	152.0	COG5640@1|root,COG5640@2|Bacteria,1R56C@1224|Proteobacteria,2UQZB@28211|Alphaproteobacteria,2K9F3@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
k59_932159_1	90814.KL370891_gene1739	1.72e-35	125.0	COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,460TU@72273|Thiotrichales	72273|Thiotrichales	Q	Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
k59_932159_2	90814.KL370891_gene1740	5.72e-25	98.6	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,462AC@72273|Thiotrichales	72273|Thiotrichales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_932171_1	1123518.ARWI01000001_gene885	8.09e-111	341.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales	72273|Thiotrichales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_932171_2	1123518.ARWI01000001_gene886	1.56e-129	383.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,460CV@72273|Thiotrichales	72273|Thiotrichales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_1498693_1	555778.Hneap_0780	5.38e-71	228.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXYB@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_932188_1	1244869.H261_13975	1.67e-82	255.0	COG1082@1|root,COG1082@2|Bacteria,1PP64@1224|Proteobacteria,2TUVQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
k59_481999_1	1484460.JSWG01000005_gene2693	1.67e-106	321.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1HXCK@117743|Flavobacteriia	976|Bacteroidetes	H	Pfam GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_86429_1	714943.Mucpa_4859	1.93e-81	251.0	COG0596@1|root,COG0596@2|Bacteria,4NZUP@976|Bacteroidetes,1J0KI@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_28085_1	272559.BF9343_2740	8.04e-10	63.2	COG3409@1|root,COG3409@2|Bacteria,4NFKN@976|Bacteroidetes,2FUR4@200643|Bacteroidia,4ASJH@815|Bacteroidaceae	976|Bacteroidetes	M	N-acetylmuramidase	-	-	-	-	-	-	-	-	-	-	-	-	Muraidase,PG_binding_1
k59_1553360_1	313598.MED152_02340	2.91e-18	84.7	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia,3VVYY@52959|Polaribacter	976|Bacteroidetes	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_1553360_2	929558.SMGD1_1919	2.49e-42	159.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
k59_424885_1	1249480.B649_02255	4.74e-08	53.5	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_896170_1	1237149.C900_03268	1.85e-101	306.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,47JUF@768503|Cytophagia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_502259_1	929558.SMGD1_1512	5.79e-05	44.3	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_502259_2	929558.SMGD1_1512	1.05e-52	176.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_274772_1	717605.Theco_3680	1.29e-05	48.1	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,26SFV@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_274772_2	929558.SMGD1_1298	1.09e-82	251.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42R1M@68525|delta/epsilon subdivisions,2YNZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, iron-sulfur protein	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_730987_2	572480.Arnit_1813	1.86e-102	303.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,42NWM@68525|delta/epsilon subdivisions,2YTR1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_274777_1	1123228.AUIH01000002_gene1474	1.25e-98	313.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XIAY@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	gacS	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
k59_161557_1	929558.SMGD1_0755	6.06e-45	154.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_161557_2	563040.Saut_1655	7.28e-22	93.6	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_444884_1	411154.GFO_1007	4.21e-86	258.0	COG0652@1|root,COG0652@2|Bacteria,4NMG5@976|Bacteroidetes,1I0CC@117743|Flavobacteriia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_444884_2	1121931.AUHG01000012_gene2899	3.83e-10	58.9	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1HY9K@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_612238_1	1172190.M947_01900	1.98e-40	147.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2YMFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
k59_612238_2	563040.Saut_1416	1.62e-33	126.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1802413_1	1123518.ARWI01000001_gene2361	1.55e-116	348.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,46020@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_556596_1	1168065.DOK_08804	4.47e-15	79.7	COG3489@1|root,COG3489@2|Bacteria,1MWBW@1224|Proteobacteria,1S2FI@1236|Gammaproteobacteria,1J81N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Imelysin	-	-	-	ko:K07338	-	-	-	-	ko00000	-	-	-	Peptidase_M75
k59_1403434_1	1392488.JHZY01000002_gene675	1.91e-37	135.0	28PP9@1|root,2ZCBQ@2|Bacteria,4NM7M@976|Bacteroidetes,1I1V7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1351343_1	1353528.DT23_04775	1.46e-72	229.0	COG3861@1|root,COG3861@2|Bacteria,1N0R6@1224|Proteobacteria,2U9AS@28211|Alphaproteobacteria,2XM4R@285107|Thioclava	28211|Alphaproteobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
k59_672426_1	865937.Gilli_3112	2.83e-44	157.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,1HZPN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1179239_1	1123514.KB905899_gene1156	2.36e-105	316.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,460A4@72273|Thiotrichales	72273|Thiotrichales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_1224943_1	1172190.M947_09765	1.14e-77	234.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2YPJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_1224943_2	1172190.M947_09760	4.41e-75	238.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_672435_1	1336233.JAEH01000004_gene1460	2.27e-35	125.0	28IIR@1|root,2Z8JS@2|Bacteria,1QAX0@1224|Proteobacteria,1RQN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_333208_1	929556.Solca_0345	7.28e-08	53.9	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
k59_1351370_2	1123518.ARWI01000001_gene1704	1.03e-272	754.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria,45ZTG@72273|Thiotrichales	72273|Thiotrichales	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1460356_1	1565129.JSFF01000014_gene423	7.22e-50	164.0	2CHGH@1|root,32S61@2|Bacteria,1MZN3@1224|Proteobacteria,1S9S8@1236|Gammaproteobacteria,2QC1N@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	VV12079	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_1460356_2	1565129.JSFF01000014_gene422	6.44e-83	272.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,2Q92X@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_556645_1	1137281.D778_01957	3.34e-87	268.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_161638_1	1123518.ARWI01000001_gene2391	8.64e-63	214.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales	72273|Thiotrichales	M	PFAM AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k59_1520169_2	1121875.KB907548_gene1577	4.44e-50	164.0	2C7KN@1|root,32RJD@2|Bacteria,4NR1V@976|Bacteroidetes,1I42C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1688774_1	1121035.AUCH01000005_gene101	2.69e-41	154.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales	206389|Rhodocyclales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1460392_1	1537917.JU82_04635	1.15e-130	384.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_107604_1	929558.SMGD1_1192	1.66e-52	169.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2YP6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_107604_2	929558.SMGD1_1193	4.09e-126	369.0	COG2199@1|root,COG2199@2|Bacteria,1QZ2R@1224|Proteobacteria,43CET@68525|delta/epsilon subdivisions,2YTCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_333249_1	1123518.ARWI01000001_gene488	2.2e-24	100.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,1RR6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_333249_2	1123518.ARWI01000001_gene486	5.77e-129	374.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,460XV@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_333249_3	1123518.ARWI01000001_gene485	3.54e-233	646.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,4609K@72273|Thiotrichales	1236|Gammaproteobacteria	E	Aminotransferase class-V	pucG	-	2.6.1.112	ko:K00839	ko00230,map00230	-	R10908	RC00018,RC03305	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
k59_47412_1	1286171.EAL2_c20710	7.89e-07	50.1	COG2111@1|root,COG2111@2|Bacteria,1VPIK@1239|Firmicutes,24VEZ@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1403512_1	870187.Thini_0009	3.43e-77	235.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria,4613F@72273|Thiotrichales	72273|Thiotrichales	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,MipZ
k59_1403512_2	426114.THI_2048	4.41e-23	91.7	2ERFX@1|root,33J1G@2|Bacteria,1NMD8@1224|Proteobacteria,2W59A@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
k59_1005451_1	929558.SMGD1_0104	8.01e-90	280.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1520219_1	458817.Shal_0004	8.98e-109	335.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,2Q924@267890|Shewanellaceae	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_839219_1	1121931.AUHG01000010_gene719	9.54e-47	166.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_731149_1	675815.VOA_000192	1.85e-45	155.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1RNQF@1236|Gammaproteobacteria,1XSBT@135623|Vibrionales	135623|Vibrionales	P	permease	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
k59_731149_2	575788.VS_II1211	2.2e-57	191.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,1RRH3@1236|Gammaproteobacteria,1XV4I@135623|Vibrionales	135623|Vibrionales	G	ABC transporter	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
k59_220315_1	1172190.M947_00405	5.33e-141	407.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2YMJ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_556730_1	326298.Suden_1037	1.07e-64	218.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42PDD@68525|delta/epsilon subdivisions,2YMYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_786499_2	929558.SMGD1_0041	3.34e-66	214.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1066982_1	572480.Arnit_2616	2.83e-111	354.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_390421_2	929558.SMGD1_0977	1.65e-45	147.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2YQA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_390421_3	326298.Suden_0296	6.17e-46	149.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2YP6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_1181497_1	983544.Lacal_2025	2.24e-31	120.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_1181497_2	983548.Krodi_0250	5.77e-37	133.0	2CZRP@1|root,32T6Z@2|Bacteria,4NSME@976|Bacteroidetes,1I3D9@117743|Flavobacteriia,37FK8@326319|Dokdonia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1181497_3	1137281.D778_01253	5.44e-120	359.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Beta-lactamase2,DUF3471
k59_733270_1	1137281.D778_01769	3.55e-06	48.9	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1I22W@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_733270_2	483216.BACEGG_03503	3.52e-35	123.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,2FNH1@200643|Bacteroidia,4AN50@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
k59_1124820_1	1123518.ARWI01000001_gene1804	9.78e-212	594.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,461UK@72273|Thiotrichales	72273|Thiotrichales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05590	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,Helicase_C
k59_898409_1	143224.JQMD01000002_gene2437	4.41e-184	525.0	COG0582@1|root,COG0582@2|Bacteria,4NI9Q@976|Bacteroidetes,1HZR0@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
k59_841144_1	323850.Shew_0039	3.28e-115	350.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,1RMSV@1236|Gammaproteobacteria,2Q99R@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_1405301_1	929558.SMGD1_2234	7.81e-98	288.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2YT4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase maturation protease	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_1405301_2	749222.Nitsa_0076	4.05e-37	130.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_733281_1	929558.SMGD1_2649	4.63e-189	544.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1294700_1	746697.Aeqsu_0814	1.88e-44	155.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
k59_1294700_2	313590.MED134_11281	1.98e-57	191.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia,37E1P@326319|Dokdonia	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
k59_1630305_1	1336233.JAEH01000004_gene1616	0.000599	41.6	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,2Q8Y2@267890|Shewanellaceae	1236|Gammaproteobacteria	E	TIGRFAM amino acid carrier protein	dagA	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1630305_2	425104.Ssed_0588	3.16e-60	192.0	2CFXK@1|root,2Z9V3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_898428_1	717773.Thicy_0363	5.41e-138	404.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,45ZT8@72273|Thiotrichales	72273|Thiotrichales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_1353641_1	1123514.KB905899_gene988	5.23e-293	816.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,461NV@72273|Thiotrichales	72273|Thiotrichales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_1353641_2	90814.KL370891_gene1091	4.08e-91	282.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,461U0@72273|Thiotrichales	72273|Thiotrichales	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
k59_1353643_1	411154.GFO_3171	1.84e-86	263.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
k59_1227248_1	90814.KL370891_gene207	3.35e-79	241.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,46069@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
k59_335540_2	1117647.M5M_01935	0.00014	43.9	COG2885@1|root,COG2885@2|Bacteria,1R9HA@1224|Proteobacteria,1RYNB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_841202_1	1123367.C666_01710	5.07e-65	209.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,2KUPR@206389|Rhodocyclales	206389|Rhodocyclales	T	alginate biosynthesis protein AlgZ FimS	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
k59_1227266_1	411154.GFO_2330	1.39e-80	259.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_1067072_1	537970.HCAN_0429	1.72e-38	152.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_1067072_2	709032.Sulku_0745	1.12e-31	124.0	COG3829@1|root,COG3829@2|Bacteria,1QQYY@1224|Proteobacteria,42ZWP@68525|delta/epsilon subdivisions,2YRT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1405348_2	944547.ABLL_0809	1.96e-52	174.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2YMZ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NeuB family	legI	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576	2.5.1.101	ko:K18430	ko00520,map00520	-	R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_109779_1	563040.Saut_1460	4.49e-21	90.5	COG2199@1|root,COG2199@2|Bacteria,1Q2N5@1224|Proteobacteria,42VZ7@68525|delta/epsilon subdivisions,2YQIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_516753_1	760154.Sulba_2284	6.71e-63	214.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2
k59_1363485_1	1178825.ALIH01000017_gene662	4.23e-312	883.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
k59_1363495_1	572480.Arnit_0598	4.75e-13	64.7	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1363495_2	572480.Arnit_0599	1.89e-123	360.0	COG2404@1|root,COG2404@2|Bacteria,1NHB1@1224|Proteobacteria,42NB0@68525|delta/epsilon subdivisions,2YMQ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
k59_8446_1	1178825.ALIH01000013_gene485	2.53e-39	139.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1HX0W@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_8446_2	1380600.AUYN01000006_gene809	2.22e-119	346.0	COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,1HXJH@117743|Flavobacteriia	976|Bacteroidetes	H	coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k59_178637_1	1380600.AUYN01000006_gene451	1.31e-25	110.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1477154_1	1380600.AUYN01000001_gene2358	1.12e-163	464.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1HZFD@117743|Flavobacteriia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1477154_2	391603.FBALC1_11057	2.96e-76	241.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_742783_1	1123518.ARWI01000001_gene245	1.4e-39	142.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,4608Y@72273|Thiotrichales	72273|Thiotrichales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_742783_2	1123518.ARWI01000001_gene246	6.06e-33	114.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_742783_3	90814.KL370891_gene1038	3.15e-201	578.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,45ZN1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_799888_1	1123518.ARWI01000001_gene1824	1.91e-156	462.0	29DE2@1|root,300BX@2|Bacteria,1NC7M@1224|Proteobacteria,1SFWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1137984_1	1167006.UWK_01992	1.81e-74	241.0	COG1835@1|root,COG1835@2|Bacteria,1RHQR@1224|Proteobacteria	1224|Proteobacteria	I	acyltransferase 3	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_404345_1	1121931.AUHG01000011_gene2079	3.46e-171	490.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_855544_1	483215.BACFIN_06391	1.97e-227	653.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMMF@200643|Bacteroidia,4ANZU@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_855544_2	743722.Sph21_4243	3.82e-41	154.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1IQ6S@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI,ROK
k59_630265_1	1123518.ARWI01000001_gene1054	1.29e-211	593.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,45ZYU@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_65498_1	1132509.C447_13197	5.8e-22	100.0	COG3119@1|root,arCOG02785@2157|Archaea,2XU7V@28890|Euryarchaeota,23T6D@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Sulfatase
k59_404355_1	1178825.ALIH01000008_gene765	1.41e-191	543.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_1647124_1	411154.GFO_0363	4.82e-200	562.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
k59_1137999_1	504487.JCM19302_33	2.88e-155	455.0	COG0417@1|root,COG0417@2|Bacteria,4NGEJ@976|Bacteroidetes,1HXZC@117743|Flavobacteriia	976|Bacteroidetes	L	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1533311_1	572480.Arnit_2669	1.56e-104	324.0	COG0699@1|root,COG0699@2|Bacteria,1NAXY@1224|Proteobacteria,42NA8@68525|delta/epsilon subdivisions,2YN7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_347162_1	62928.azo2168	2.48e-73	226.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,2KVFV@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_347162_2	497321.C664_01600	4.69e-62	202.0	28I8W@1|root,2Z8BP@2|Bacteria,1N0SC@1224|Proteobacteria,2VK0J@28216|Betaproteobacteria,2KVDQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2863
k59_630271_1	317025.Tcr_0757	1.83e-53	175.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,461ZM@72273|Thiotrichales	72273|Thiotrichales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_630271_2	1123514.KB905899_gene1408	3.71e-57	196.0	2EIBS@1|root,33C35@2|Bacteria,1QVXE@1224|Proteobacteria,1SHEY@1236|Gammaproteobacteria,463BH@72273|Thiotrichales	72273|Thiotrichales	S	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_630271_3	1168067.JAGP01000001_gene742	1.32e-75	231.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,462RB@72273|Thiotrichales	72273|Thiotrichales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_630271_4	90814.KL370891_gene724	3.64e-72	217.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,462JU@72273|Thiotrichales	72273|Thiotrichales	KT	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_1760144_1	411154.GFO_1876	4.98e-52	165.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1I41M@117743|Flavobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_1760144_2	411154.GFO_1877	1.23e-47	154.0	2E695@1|root,330X7@2|Bacteria,4NVE0@976|Bacteroidetes,1I53C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1477202_1	504487.JCM19302_3906	9.44e-239	681.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_1251015_1	572480.Arnit_0236	9.18e-133	384.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2YN1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1081232_1	1137281.D778_02459	2.27e-116	345.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_1081232_2	1121912.AUHD01000001_gene2318	6.97e-185	522.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_913930_5	1175654.A0A0S0N2M1_9CAUD	1.17e-06	52.8	4QDEN@10239|Viruses,4R0G3@35237|dsDNA viruses  no RNA stage,4QQNS@28883|Caudovirales,4QKQB@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1252677_1	1121931.AUHG01000011_gene2359	1.91e-115	342.0	2EXUR@1|root,33R3Z@2|Bacteria,4P0U2@976|Bacteroidetes,1I84A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1534932_1	411154.GFO_0510	3e-171	484.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWRZ@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1310307_1	1172190.M947_05695	1.21e-39	140.0	COG0697@1|root,COG0697@2|Bacteria,1R8RU@1224|Proteobacteria,42SDJ@68525|delta/epsilon subdivisions,2YPDW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1310307_2	929558.SMGD1_1401	1.15e-74	233.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2YTP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_1193779_1	90814.KL370891_gene1903	8.01e-57	180.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	rhodanese-related sulfurtransferase	yibN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_1193779_2	90814.KL370891_gene1904	1.98e-101	309.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,46079@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1365218_1	318161.Sden_1948	3.61e-123	376.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,2Q8M3@267890|Shewanellaceae	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_180448_2	1232410.KI421424_gene1767	4.6e-30	108.0	COG5336@1|root,COG5336@2|Bacteria,1Q3U8@1224|Proteobacteria,437BR@68525|delta/epsilon subdivisions,2X2H2@28221|Deltaproteobacteria,43VQW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_180448_3	1232410.KI421424_gene1768	6.97e-31	117.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1139582_1	1380600.AUYN01000002_gene6	2.07e-83	247.0	2ASGC@1|root,31HWH@2|Bacteria,4NR0Q@976|Bacteroidetes,1I25V@117743|Flavobacteriia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_1139582_2	1178825.ALIH01000010_gene431	0.0	1213.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1139582_3	1380600.AUYN01000002_gene4	2.99e-170	528.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_10170_1	1470593.BW43_01062	1.66e-34	134.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	pleD	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1365238_1	1121931.AUHG01000017_gene1513	6.87e-131	397.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_1705141_1	980584.AFPB01000138_gene2693	6.39e-30	108.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia,4069Z@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	J	Ribosomal protein S12/S23	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_1705141_2	1178825.ALIH01000001_gene2588	8.63e-100	290.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1HWP7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_1705141_3	391587.KAOT1_12202	4.77e-126	378.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1HY04@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1139598_1	1123518.ARWI01000001_gene1163	1.54e-122	373.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_67269_1	207954.MED92_11434	8.46e-96	286.0	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XHRF@135619|Oceanospirillales	135619|Oceanospirillales	S	ABC transporter, ATP-binding protein	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
k59_67269_2	400668.Mmwyl1_0950	4.35e-28	110.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1XH3N@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_1422429_1	1232410.KI421424_gene1763	2.94e-98	302.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria,43U5U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c3	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
k59_1705149_1	1137281.D778_02098	1.15e-77	241.0	28JMY@1|root,2Z9ED@2|Bacteria,4NGSX@976|Bacteroidetes,1HYMA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	-
k59_801738_1	1121931.AUHG01000010_gene427	2.32e-71	220.0	2EQ2R@1|root,33HP4@2|Bacteria,4NZ0U@976|Bacteroidetes,1I6WR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_801738_2	411154.GFO_3445	1.45e-111	332.0	COG0520@1|root,COG0520@2|Bacteria,4NJCB@976|Bacteroidetes,1I0MB@117743|Flavobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_462949_1	504487.JCM19302_84	1.5e-38	133.0	2EDFS@1|root,337BZ@2|Bacteria,4NW63@976|Bacteroidetes,1I566@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_462949_2	1380384.JADN01000007_gene1538	4.58e-44	151.0	2E5XB@1|root,32TRA@2|Bacteria,4NSFZ@976|Bacteroidetes,1I41W@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4251)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4251
k59_67287_1	1121931.AUHG01000011_gene1809	3.05e-103	308.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1HXRQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_293071_1	1450525.JATV01000010_gene1617	3.33e-26	112.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,2NT81@237|Flavobacterium	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_123271_1	1380600.AUYN01000009_gene1825	2.76e-30	115.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_123271_2	1137281.D778_00601	3.59e-87	261.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123271_3	1178825.ALIH01000001_gene2692	3.68e-84	253.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_575511_1	1122179.KB890469_gene596	2.96e-29	126.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,Reg_prop,Response_reg,Y_Y_Y
k59_575511_2	420890.LCGL_1682	3.35e-65	214.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,1YBEN@1357|Lactococcus	91061|Bacilli	G	Aldose 1-epimerase	lacX	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_857371_1	1121895.Q765_11985	0.000518	52.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4PPM7@976|Bacteroidetes,1IKQX@117743|Flavobacteriia,2NSJ1@237|Flavobacterium	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_857371_2	1223410.KN050846_gene1094	1.79e-07	57.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Sortilin-Vps10
k59_67293_1	1137281.D778_00334	7.55e-22	92.8	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_67293_2	1178825.ALIH01000019_gene1239	8.18e-111	320.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
k59_67293_3	504487.JCM19302_1772	1.98e-122	355.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_348891_1	641526.ADIWIN_1047	1.89e-153	435.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1HX31@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_10249_1	411154.GFO_3262	6.05e-84	248.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_10249_2	411154.GFO_3263	2.01e-38	140.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_801798_1	1279009.ADICEAN_00907	1.61e-50	179.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
k59_1422492_1	1121931.AUHG01000017_gene1539	9.92e-135	389.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
k59_1365316_1	929558.SMGD1_0815	9.89e-34	136.0	COG1195@1|root,COG1195@2|Bacteria,1R0Y3@1224|Proteobacteria,42NCY@68525|delta/epsilon subdivisions,2YN22@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_857426_1	1121931.AUHG01000012_gene2658	4.97e-102	315.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_237143_1	1123234.AUKI01000001_gene1920	1.49e-91	277.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1I0HE@117743|Flavobacteriia	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_237143_2	1121931.AUHG01000012_gene2592	5.91e-50	167.0	COG0628@1|root,COG0628@2|Bacteria,4NFB2@976|Bacteroidetes,1HZR1@117743|Flavobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_744595_1	1178825.ALIH01000006_gene1380	6e-214	598.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1HX3F@117743|Flavobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1310461_1	572480.Arnit_1797	4.79e-165	463.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2YR2N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1310461_2	572480.Arnit_1796	3.33e-40	139.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2YR2A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Abc transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_180575_1	983544.Lacal_1823	5.29e-23	93.6	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1HZJ6@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_180575_2	983544.Lacal_1824	2.78e-103	300.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1HXJG@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_180575_3	1178825.ALIH01000017_gene685	1.1e-68	209.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_180575_4	1380600.AUYN01000001_gene2733	1.98e-245	709.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_870526_1	1046714.AMRX01000007_gene2188	6.2e-33	130.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465AJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,PAS,PAS_8,PAS_9
k59_870526_2	563040.Saut_1414	5.18e-98	297.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2YMN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iIT341.HP0976	AAA_26,Aminotran_3
k59_702666_1	1565129.JSFF01000009_gene1768	2.67e-17	73.9	2ASUE@1|root,31I9T@2|Bacteria,1QFZ6@1224|Proteobacteria,1TDAS@1236|Gammaproteobacteria,2QCTN@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_702666_2	425104.Ssed_0599	2.74e-32	118.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,2Q8VA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k59_1265614_1	1353528.DT23_13945	5.37e-95	288.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,2XKHB@285107|Thioclava	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	bztB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_926327_1	1122225.AULQ01000005_gene2497	1.14e-07	52.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_926327_2	1197477.IA57_03480	1.58e-122	352.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1HXI6@117743|Flavobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
k59_926327_3	1137281.D778_01417	1.28e-63	198.0	COG4314@1|root,COG4314@2|Bacteria,4NVVP@976|Bacteroidetes,1I2Z0@117743|Flavobacteriia	976|Bacteroidetes	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
k59_926327_4	1121011.AUCB01000002_gene445	7.59e-11	62.8	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,23G8V@178469|Arenibacter	976|Bacteroidetes	P	Domain present in carbohydrate binding proteins and sugar hydrolses	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
k59_815164_2	1177928.TH2_09124	1.48e-20	92.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2JQVF@204441|Rhodospirillales	204441|Rhodospirillales	V	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_306020_1	563040.Saut_1540	7.9e-70	233.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z31@68525|delta/epsilon subdivisions,2YRAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Hpt sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1151753_1	1380600.AUYN01000006_gene278	9.93e-24	99.4	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_1151753_2	1443665.JACA01000001_gene2960	3.7e-36	131.0	COG1609@1|root,COG1609@2|Bacteria,4NFB7@976|Bacteroidetes,1HYFS@117743|Flavobacteriia,2YIT8@290174|Aquimarina	976|Bacteroidetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
k59_926329_1	1172190.M947_05960	1.14e-74	228.0	COG5456@1|root,COG5456@2|Bacteria,1Q27X@1224|Proteobacteria,42V4G@68525|delta/epsilon subdivisions,2YQE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_756834_1	563040.Saut_0096	5.59e-95	290.0	COG1293@1|root,COG1293@2|Bacteria,1R54S@1224|Proteobacteria,42MYG@68525|delta/epsilon subdivisions,2YT8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_756834_2	1172190.M947_08145	1.31e-17	77.8	2ANKR@1|root,31DJY@2|Bacteria,1QAVT@1224|Proteobacteria,42VKM@68525|delta/epsilon subdivisions,2YQB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1661872_1	1178825.ALIH01000013_gene491	1.62e-157	456.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
k59_1434684_3	2340.JV46_02100	2.77e-09	62.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1J7KE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_1265623_1	1250006.JHZZ01000001_gene2224	3.62e-127	377.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,3VWJ7@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_978998_2	1172190.M947_07655	3.48e-34	125.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_756846_1	1178825.ALIH01000001_gene2311	2.13e-259	716.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1HZDM@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_587939_1	1121931.AUHG01000010_gene639	4.93e-82	256.0	COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,1HY19@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
k59_418900_1	1232410.KI421421_gene3566	5.17e-57	192.0	COG1524@1|root,COG1524@2|Bacteria,1QX9K@1224|Proteobacteria	1224|Proteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_872642_1	1144313.PMI10_03513	2.09e-240	667.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HXEA@117743|Flavobacteriia,2NTF3@237|Flavobacterium	976|Bacteroidetes	G	Pfam Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
k59_82520_1	85643.Tmz1t_2365	1.27e-84	252.0	COG1988@1|root,COG1988@2|Bacteria,1RE5Y@1224|Proteobacteria,2W2UE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_82520_2	85643.Tmz1t_2366	3.96e-30	113.0	2E5EF@1|root,3306D@2|Bacteria,1ND5R@1224|Proteobacteria,2W4XH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1777537_1	305700.B447_05473	7.12e-72	221.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,2KUTX@206389|Rhodocyclales	206389|Rhodocyclales	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_590058_1	458817.Shal_1042	6.74e-144	428.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PPHF@1224|Proteobacteria,1RYDI@1236|Gammaproteobacteria,2QAYG@267890|Shewanellaceae	1236|Gammaproteobacteria	KU	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
k59_363417_1	1380600.AUYN01000001_gene2343	7.82e-183	529.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
k59_82526_1	1380600.AUYN01000009_gene1139	1.13e-124	367.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1HWPY@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_24350_1	1380600.AUYN01000007_gene3140	2.63e-83	252.0	2AZZ1@1|root,31S92@2|Bacteria,4NR5H@976|Bacteroidetes,1I0PY@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k59_252465_1	317025.Tcr_2047	2.77e-59	192.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,462MK@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_252465_2	1123514.KB905899_gene2034	4.85e-50	176.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,461PB@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1720370_1	929558.SMGD1_2373	8.86e-75	231.0	COG0650@1|root,COG0650@2|Bacteria,1QUK1@1224|Proteobacteria,42PHN@68525|delta/epsilon subdivisions,2YTP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH dehydrogenase	-	-	-	ko:K14087	-	-	-	-	ko00000	-	-	-	NADHdh
k59_252495_2	458817.Shal_1945	1.78e-78	238.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,2QA20@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein TetR	psrA	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1326064_1	1380600.AUYN01000007_gene3227	1.77e-39	144.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_1379976_1	1380600.AUYN01000007_gene3175	3.16e-65	217.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl endopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_1379976_2	1286632.P278_27400	5.34e-07	51.2	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_872700_1	945713.IALB_0499	2.8e-44	149.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_1379978_1	1446473.JHWH01000036_gene2160	1.39e-144	422.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2PWVV@265|Paracoccus	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k59_533998_1	1121931.AUHG01000012_gene2648	1.14e-144	419.0	COG0668@1|root,COG0668@2|Bacteria,4NE4R@976|Bacteroidetes,1HXQS@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	mscS2	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
k59_817454_1	1120973.AQXL01000119_gene539	0.000437	45.8	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,278N7@186823|Alicyclobacillaceae	91061|Bacilli	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
k59_817454_2	694427.Palpr_1353	1.01e-14	76.3	COG2966@1|root,COG2966@2|Bacteria,4NI61@976|Bacteroidetes,2FNR6@200643|Bacteroidia,2307V@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
k59_1494780_1	1123518.ARWI01000001_gene1566	3.39e-160	454.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,4607M@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_1494780_2	90814.KL370892_gene2121	1.34e-25	102.0	COG3619@1|root,COG3619@2|Bacteria,1RB5Q@1224|Proteobacteria,1RRG5@1236|Gammaproteobacteria,4619N@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
k59_647220_1	572480.Arnit_2999	1.24e-218	606.0	COG2301@1|root,COG2301@2|Bacteria,1PCZW@1224|Proteobacteria,42ZE1@68525|delta/epsilon subdivisions,2YRAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
k59_1549594_1	143224.JQMD01000002_gene3015	5.59e-95	286.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1HY0C@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_1549594_2	491952.Mar181_0945	8.71e-06	48.1	COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,1T31H@1236|Gammaproteobacteria,1XH90@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
k59_872735_1	425104.Ssed_2367	1.48e-55	188.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S66J@1236|Gammaproteobacteria,2QB6B@267890|Shewanellaceae	1236|Gammaproteobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ
k59_1549603_1	1392490.JHZX01000001_gene2747	1.61e-74	248.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1I0F2@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_1608656_1	504487.JCM19302_3968	3.09e-155	442.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1HWY3@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
k59_1154154_1	90814.KL370891_gene132	1.24e-66	213.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,460S3@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1154154_2	1026882.MAMP_00444	2.4e-12	62.8	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,461BQ@72273|Thiotrichales	72273|Thiotrichales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
k59_1380023_1	1172190.M947_04550	6.98e-124	363.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2YMPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_759151_1	1123518.ARWI01000001_gene2164	1.37e-194	552.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_534049_1	398720.MED217_04967	2.88e-24	99.8	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1HZXZ@117743|Flavobacteriia,2XK64@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
k59_534049_2	1178825.ALIH01000015_gene1918	1.22e-68	211.0	COG1917@1|root,COG1917@2|Bacteria,4NM8B@976|Bacteroidetes,1I17U@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_82635_1	1380600.AUYN01000001_gene2671	2.58e-139	447.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_590176_1	411154.GFO_2813	9.1e-85	253.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia	976|Bacteroidetes	J	ribosomal protein l17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_928568_2	382464.ABSI01000014_gene1450	6.15e-08	53.5	COG1606@1|root,COG1606@2|Bacteria,46VAE@74201|Verrucomicrobia,2IUM5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase
k59_1326137_1	748247.AZKH_2843	8.97e-07	49.7	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,2KXA7@206389|Rhodocyclales	206389|Rhodocyclales	T	Anti sigma-E protein RseA	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
k59_1326137_2	1348657.M622_02330	5.82e-81	250.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma E regulatory protein, MucB RseB	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
k59_308288_1	1496688.ER33_11620	3.08e-32	122.0	COG0517@1|root,COG0517@2|Bacteria,1GMG5@1117|Cyanobacteria,22TA4@167375|Cyanobium	1117|Cyanobacteria	S	transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_308288_2	1123053.AUDG01000129_gene1759	1.16e-17	80.5	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1S0AJ@1236|Gammaproteobacteria,1X141@135613|Chromatiales	135613|Chromatiales	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
k59_478175_1	62928.azo3600	2.35e-93	297.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KUC6@206389|Rhodocyclales	206389|Rhodocyclales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1608688_1	1197477.IA57_02565	1.56e-54	181.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_1549633_1	572480.Arnit_3058	2.2e-160	474.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43EDT@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	3.1.4.52	ko:K20964	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF3365,EAL,FIST,FIST_C,GGDEF,PAS_9,dCache_3
k59_1664096_1	411154.GFO_2387	6.54e-50	159.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1I50J@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_1664096_2	411154.GFO_2388	2e-57	187.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_82649_1	1469557.JSWF01000014_gene2652	2.12e-108	335.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_1380058_1	1565129.JSFF01000003_gene2227	2.33e-100	318.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q9AP@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_137890_1	1458275.AZ34_13435	1.95e-22	98.2	COG3206@1|root,COG3206@2|Bacteria,1RK0N@1224|Proteobacteria,2VHPS@28216|Betaproteobacteria,4AA01@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chain length determinant protein	gumC	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_137890_2	1265502.KB905942_gene2836	5.03e-58	194.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VN0C@28216|Betaproteobacteria,4ADT4@80864|Comamonadaceae	28216|Betaproteobacteria	D	Capsular exopolysaccharide family	epsG	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_137890_3	395495.Lcho_2352	6.42e-61	199.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VHWW@28216|Betaproteobacteria,1KJHI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k59_817529_1	563040.Saut_1140	4.54e-30	110.0	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_24479_1	709032.Sulku_2371	3.31e-186	527.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1326160_1	411154.GFO_1813	1.1e-82	249.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1I17Y@117743|Flavobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1326160_2	1443665.JACA01000005_gene279	9.23e-43	149.0	COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,1HYM4@117743|Flavobacteriia,2YGJY@290174|Aquimarina	976|Bacteroidetes	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1608711_1	317025.Tcr_0250	4.31e-104	322.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,45ZVF@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_705365_1	1537915.JU57_05190	2.77e-16	79.3	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_705365_2	1537915.JU57_05185	1.57e-175	523.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2YN89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_1494840_1	1123037.AUDE01000009_gene1270	7.9e-164	471.0	COG0438@1|root,COG0438@2|Bacteria,4NFKP@976|Bacteroidetes,1HXK3@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 1	wbsE	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
k59_1494840_2	1178825.ALIH01000017_gene655	2.76e-127	376.0	COG0438@1|root,COG0438@2|Bacteria,4NM0R@976|Bacteroidetes,1HX69@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	2.4.1.291	ko:K17248	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1494840_3	391598.FBBAL38_01630	6.08e-59	185.0	COG0662@1|root,COG0662@2|Bacteria,4NQ4K@976|Bacteroidetes,1I2VJ@117743|Flavobacteriia	976|Bacteroidetes	G	domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
k59_1494840_4	1046627.BZARG_1907	2.52e-85	266.0	COG1216@1|root,COG1216@2|Bacteria,4PKGS@976|Bacteroidetes,1IJRT@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1494840_5	1131812.JQMS01000001_gene1750	1.2e-90	278.0	COG0463@1|root,COG0463@2|Bacteria,4PKQ4@976|Bacteroidetes,1IKCS@117743|Flavobacteriia,2P0QI@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1494840_6	1178825.ALIH01000017_gene660	9.81e-121	350.0	COG2227@1|root,COG2227@2|Bacteria,4NK5C@976|Bacteroidetes,1HZ6H@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_1494840_7	504487.JCM19302_3302	7.7e-73	223.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_1112983_5	391603.FBALC1_16787	5.01e-107	319.0	COG2755@1|root,COG2755@2|Bacteria,4NFVN@976|Bacteroidetes,1HZ3W@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_97926_1	929558.SMGD1_0537	1.1e-131	381.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
k59_1112984_1	1121931.AUHG01000011_gene2104	1.69e-40	146.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,1HXFQ@117743|Flavobacteriia	976|Bacteroidetes	M	ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_378421_1	411154.GFO_3152	3.93e-60	189.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1I1BT@117743|Flavobacteriia	976|Bacteroidetes	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_378421_2	411154.GFO_3151	2.99e-38	137.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1215206_1	1121931.AUHG01000011_gene2315	9.75e-31	119.0	COG2203@1|root,COG2203@2|Bacteria,4NE84@976|Bacteroidetes,1HXM4@117743|Flavobacteriia	976|Bacteroidetes	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1215206_2	1121931.AUHG01000011_gene2316	4.78e-71	224.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1HWWN@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_1055569_1	225849.swp_1111	3.34e-64	211.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,2QANX@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_210853_1	1123518.ARWI01000001_gene295	1.4e-32	120.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria	1224|Proteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_210853_2	1123518.ARWI01000001_gene296	4.65e-115	351.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,462HE@72273|Thiotrichales	72273|Thiotrichales	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF294,DUF294_C
k59_1564761_1	323850.Shew_1491	3.3e-57	184.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,2Q93U@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Ion transport 2 domain protein	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k59_1564761_2	1123033.ARNF01000083_gene1649	1.09e-11	63.2	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,3NJMU@468|Moraxellaceae	1236|Gammaproteobacteria	S	L,D-transpeptidase catalytic domain	IV02_27405	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_210856_1	391603.FBALC1_04402	2.67e-22	90.1	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I17E@117743|Flavobacteriia	976|Bacteroidetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_832944_1	62928.azo1369	1.1e-124	365.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,2KV4N@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1285254_2	1453505.JASY01000007_gene1163	6.3e-106	314.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
k59_943230_1	572480.Arnit_1649	3.59e-106	315.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,42NNZ@68525|delta/epsilon subdivisions,2YNIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_943230_2	572480.Arnit_1648	7.16e-117	341.0	COG0189@1|root,COG0189@2|Bacteria,1R4ZF@1224|Proteobacteria,42PG3@68525|delta/epsilon subdivisions,2YMQ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_776338_1	1442598.JABW01000003_gene105	1.5e-68	214.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2YNAJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_776338_2	1355374.JARU01000015_gene1051	8.45e-50	162.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42P3W@68525|delta/epsilon subdivisions,2YMZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_1737861_1	1123518.ARWI01000001_gene2338	7.66e-163	469.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,4600Z@72273|Thiotrichales	72273|Thiotrichales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_1397184_1	391603.FBALC1_14212	2.16e-86	254.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia	976|Bacteroidetes	Q	thioesterase	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_1397184_2	1197477.IA57_02125	2.45e-158	452.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia	976|Bacteroidetes	I	dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_213081_1	1219065.VPR01S_09_01200	4.11e-139	416.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XVEU@135623|Vibrionales	135623|Vibrionales	G	COG3459 Cellobiose phosphorylase	chbP	-	2.4.1.280	ko:K18675	ko00520,map00520	-	R09942	RC00049	ko00000,ko00001,ko01000	-	GH94	-	Glyco_hydro_36,Glyco_transf_36
k59_1057830_1	1027273.GZ77_17855	2.32e-06	47.8	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XIT9@135619|Oceanospirillales	135619|Oceanospirillales	E	phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_1057830_2	90814.KL370891_gene1231	1.18e-69	212.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,460NG@72273|Thiotrichales	72273|Thiotrichales	F	NUDIX domain	-	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_438504_1	1484460.JSWG01000012_gene1491	3.35e-92	276.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_438504_2	1380600.AUYN01000003_gene182	1.09e-117	344.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_665090_1	985255.APHJ01000023_gene2596	1.57e-67	217.0	COG0438@1|root,COG0438@2|Bacteria,4NJR3@976|Bacteroidetes,1IGDV@117743|Flavobacteriia,2P5XU@244698|Gillisia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_665090_2	865937.Gilli_0682	1.04e-42	149.0	COG0438@1|root,COG0438@2|Bacteria,4NGYT@976|Bacteroidetes,1HYZ0@117743|Flavobacteriia,2P6BC@244698|Gillisia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_723707_4	1132026.I6NRF1_9CAUD	2.95e-48	172.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage,4QPWY@28883|Caudovirales,4QKSZ@10699|Siphoviridae	10699|Siphoviridae	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1681274_1	1172190.M947_01800	1.93e-68	221.0	COG1538@1|root,COG1538@2|Bacteria,1Q066@1224|Proteobacteria,42RNJ@68525|delta/epsilon subdivisions,2YNZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1512685_1	1117647.M5M_06695	4.61e-42	160.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1NUIZ@1224|Proteobacteria,1RPMQ@1236|Gammaproteobacteria,1J5NY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Alpha amylase, catalytic domain	-	-	2.4.1.19	ko:K00701	ko00500,map00500	-	R11260	-	ko00000,ko00001,ko01000	-	CBM20,GH13	-	Alpha-amylase
k59_1171978_2	641526.ADIWIN_0867	7.98e-106	307.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1I08A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1171978_3	1380600.AUYN01000001_gene2368	2.87e-60	205.0	2DPCB@1|root,331HJ@2|Bacteria,4NS9W@976|Bacteroidetes	976|Bacteroidetes	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
k59_1171978_4	1380600.AUYN01000001_gene2365	3.07e-122	354.0	28HMY@1|root,2Z7WC@2|Bacteria,4NG8W@976|Bacteroidetes,1HY09@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1171978_5	1380600.AUYN01000001_gene2364	5.1e-273	759.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia	976|Bacteroidetes	E	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_665127_1	1123514.KB905901_gene121	1.41e-94	288.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,1RN0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_1681298_2	929558.SMGD1_0444	5.79e-82	260.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_155084_1	1168067.JAGP01000001_gene367	6.34e-98	291.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,45ZP8@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_155084_2	1123514.KB905901_gene40	1.9e-161	459.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_213155_1	572480.Arnit_1929	1.42e-176	495.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2YMSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Co-chaperone-curved DNA binding protein A	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_998171_1	1123033.ARNF01000032_gene877	2.5e-32	122.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,3NMH5@468|Moraxellaceae	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_998171_2	1123518.ARWI01000001_gene1436	7.77e-39	143.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,460A3@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_1285357_1	572480.Arnit_3146	6.1e-18	79.7	COG1776@1|root,COG1776@2|Bacteria,1N49I@1224|Proteobacteria,43BB2@68525|delta/epsilon subdivisions,2YSZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k59_1285357_2	572480.Arnit_3145	1.21e-72	226.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S7I@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	adrA	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS,PAS_4
k59_605881_1	929558.SMGD1_0820	7.76e-61	205.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2YMBT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_549500_1	1123228.AUIH01000025_gene3302	8.41e-32	128.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1XQAI@135619|Oceanospirillales	135619|Oceanospirillales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
k59_1567000_1	1121931.AUHG01000010_gene155	1.49e-123	374.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_1285371_1	1165841.SULAR_03492	1.71e-21	88.2	COG2128@1|root,COG2128@2|Bacteria,1PZ9M@1224|Proteobacteria,42PYF@68525|delta/epsilon subdivisions,2YNK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1285371_2	929558.SMGD1_1260	6.1e-68	212.0	COG0789@1|root,COG0789@2|Bacteria,1NFNE@1224|Proteobacteria,42TCN@68525|delta/epsilon subdivisions,2YPGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_1217456_1	1197477.IA57_06400	2.39e-188	531.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia	976|Bacteroidetes	O	assembly protein, SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_1217456_2	1178825.ALIH01000001_gene2296	5.84e-97	293.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_889850_1	929558.SMGD1_1652	9.1e-75	243.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_665189_1	387093.SUN_1947	1.7e-31	125.0	COG3307@1|root,COG3307@2|Bacteria,1N25I@1224|Proteobacteria,42RSJ@68525|delta/epsilon subdivisions,2YPDD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM O-Antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k59_776480_1	765910.MARPU_06905	5.12e-62	213.0	COG0642@1|root,COG3437@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WXIU@135613|Chromatiales	135613|Chromatiales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_380934_1	1380600.AUYN01000006_gene490	5.8e-12	65.1	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HXME@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_380934_3	1178825.ALIH01000001_gene2439	2.93e-264	746.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NEPS@976|Bacteroidetes,1HYQ1@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_7,TPR_8
k59_380934_4	1178825.ALIH01000001_gene2440	1.67e-43	147.0	COG2197@1|root,COG2197@2|Bacteria,4NHNP@976|Bacteroidetes,1I09Z@117743|Flavobacteriia	976|Bacteroidetes	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_495293_1	1380600.AUYN01000001_gene2697	2.47e-98	294.0	COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,1HYAC@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
k59_943356_1	1178825.ALIH01000008_gene822	5.96e-11	62.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_943356_2	1380600.AUYN01000006_gene313	1.43e-108	335.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_326023_1	1086011.HJ01_00168	2.21e-82	258.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,1HYU5@117743|Flavobacteriia,2P0QW@237|Flavobacterium	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
k59_1795215_1	1150621.SMUL_1510	2.08e-100	300.0	COG0420@1|root,COG0420@2|Bacteria,1Q58G@1224|Proteobacteria,42NPZ@68525|delta/epsilon subdivisions,2YNJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
k59_1057984_1	1121931.AUHG01000012_gene2690	8.16e-60	205.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_1057984_2	1121931.AUHG01000012_gene2690	3.77e-42	154.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_268651_1	234831.PSM_A1338	2.75e-29	117.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,1T2MP@1236|Gammaproteobacteria,2Q26A@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_834472_1	392500.Swoo_2162	1.39e-60	198.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria,2QAIM@267890|Shewanellaceae	1236|Gammaproteobacteria	F	PFAM Xanthine uracil vitamin C permease	uraA	GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082	-	ko:K02824,ko:K09016	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2,2.A.40.1.3	-	iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189,iSFxv_1172.SFxv_2795,iS_1188.S2690	Xan_ur_permease
k59_776539_1	1123514.KB905903_gene374	7.11e-115	341.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,4601J@72273|Thiotrichales	72273|Thiotrichales	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_100445_1	280701.Q5QF87_9CAUD	2.72e-16	75.9	4QD4R@10239|Viruses,4QUPD@35237|dsDNA viruses  no RNA stage,4QTAJ@28883|Caudovirales,4QNC6@10744|Podoviridae	10744|Podoviridae	S	Protein of unknown function (DUF3268)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1397329_1	90813.JQMT01000001_gene284	7.84e-126	389.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,460M7@72273|Thiotrichales	72273|Thiotrichales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
k59_1795249_1	929558.SMGD1_0636	3.7e-107	338.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_381002_1	1380600.AUYN01000002_gene3	2.78e-33	127.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_381002_2	745718.JADT01000011_gene762	4.31e-108	335.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_889920_1	1122225.AULQ01000002_gene736	1.21e-72	245.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_834486_1	1232410.KI421424_gene1664	1.43e-34	129.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,43S0V@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Radical SAM superfamily	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_834486_2	1121918.ARWE01000001_gene1211	4.86e-40	140.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,43SDS@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase superfamily	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
k59_943411_1	929558.SMGD1_0063	2.91e-154	444.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1S@1224|Proteobacteria,43CE1@68525|delta/epsilon subdivisions,2YTBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1285494_1	1123518.ARWI01000001_gene105	1.01e-79	252.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,460C3@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_326100_1	317025.Tcr_0037	1.07e-135	399.0	COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,1RQ07@1236|Gammaproteobacteria,460K4@72273|Thiotrichales	72273|Thiotrichales	C	Rubredoxin	-	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Rubredoxin
k59_213307_1	314292.VAS14_08665	3.64e-21	89.7	COG4107@1|root,COG4107@2|Bacteria,1MVRN@1224|Proteobacteria,1RR70@1236|Gammaproteobacteria,1XUAD@135623|Vibrionales	135623|Vibrionales	P	ATPases associated with a variety of cellular activities	phnK	-	-	ko:K05781	-	-	-	-	ko00000	-	-	-	ABC_tran
k59_213307_2	1042375.AFPL01000035_gene2870	1.54e-80	248.0	COG4778@1|root,COG4778@2|Bacteria,1MUPB@1224|Proteobacteria,1RS1I@1236|Gammaproteobacteria,469ZS@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ATPases associated with a variety of cellular activities	phnL	GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1990234	2.7.8.37	ko:K05780	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	ABC_tran
k59_381052_1	94122.Shewana3_2680	1.17e-17	80.1	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,2QB5Z@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
k59_1681504_1	1121931.AUHG01000010_gene323	1.99e-100	317.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1I0N1@117743|Flavobacteriia	976|Bacteroidetes	GV	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_998363_1	1172190.M947_01860	3.79e-103	316.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1795305_1	1278309.KB907103_gene1080	2.17e-56	191.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,1T299@1236|Gammaproteobacteria,1XI0H@135619|Oceanospirillales	135619|Oceanospirillales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_1795305_2	1278309.KB907103_gene1081	1.5e-36	127.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,1XJ4Z@135619|Oceanospirillales	135619|Oceanospirillales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_1217595_1	1120951.AUBG01000011_gene2469	2.04e-162	472.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
k59_1137109_1	563040.Saut_1084	8.6e-236	655.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YMHJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1137109_2	326298.Suden_1147	5.17e-71	221.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_290327_1	1353528.DT23_17985	1.1e-40	147.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2XNZZ@285107|Thioclava	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
k59_1307584_1	1121931.AUHG01000012_gene2874	1.36e-76	256.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_1080298_1	1165841.SULAR_02903	3.47e-32	114.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2YPV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase assembly chaperone HypC	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_1080298_2	317025.Tcr_2043	5.59e-65	204.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,460EX@72273|Thiotrichales	72273|Thiotrichales	KO	TIGRFAM Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_1191960_1	563040.Saut_0093	5.76e-79	243.0	COG4558@1|root,COG4558@2|Bacteria,1QTSV@1224|Proteobacteria,43CDY@68525|delta/epsilon subdivisions,2YTBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_1137144_1	1250005.PHEL85_1899	2.16e-63	204.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia	976|Bacteroidetes	V	transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1137144_2	1484460.JSWG01000006_gene2962	5.37e-144	409.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_234212_1	420324.KI912006_gene8709	1.42e-88	276.0	COG1653@1|root,COG1653@2|Bacteria,1N98V@1224|Proteobacteria,2TSIS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	msmE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
k59_798974_1	1237149.C900_04676	3.18e-100	322.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,47JP0@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_290374_1	998088.B565_2002	2.19e-09	53.1	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1Y4UC@135624|Aeromonadales	135624|Aeromonadales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_290374_2	1123514.KB905899_gene1380	7.05e-202	564.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,460BA@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_290374_3	90814.KL370891_gene764	3.66e-73	228.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,45ZQP@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1080318_1	62928.azo1987	1.6e-95	290.0	COG1028@1|root,COG1028@2|Bacteria,1QVCC@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc,adh_short
k59_1307633_1	869213.JCM21142_432	1.84e-108	325.0	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes,47VCU@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1646232_1	1532558.JL39_27030	2.46e-57	181.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,4BEGJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_1646232_2	1172190.M947_03670	8.19e-78	235.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2YPAC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
k59_1419934_1	411154.GFO_3518	6.45e-62	201.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1419934_2	1121931.AUHG01000010_gene547	1.04e-40	137.0	COG0454@1|root,COG0456@2|Bacteria,4NM68@976|Bacteroidetes,1I1DY@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_742014_1	411154.GFO_2327	7.14e-52	167.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_742014_2	411154.GFO_2326	4.72e-109	328.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1HY1T@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1646243_2	1537915.JU57_05190	2.01e-34	133.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,42NB9@68525|delta/epsilon subdivisions,2YNN4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_120739_1	1121912.AUHD01000005_gene1657	1.04e-103	323.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_120739_2	1178825.ALIH01000011_gene83	5.09e-98	293.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_742026_1	867900.Celly_2929	4.25e-100	306.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1HYKQ@117743|Flavobacteriia,1F7XB@104264|Cellulophaga	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k59_290408_1	313603.FB2170_07924	8.28e-224	632.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_290408_2	313603.FB2170_07929	5.12e-51	163.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1I39R@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_290408_3	313603.FB2170_07934	5.33e-79	238.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I26W@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_290408_4	1121875.KB907547_gene3145	1.11e-25	98.2	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I6VR@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
k59_1532500_1	929506.CbC4_2329	1.08e-24	104.0	COG1388@1|root,COG2503@1|root,COG1388@2|Bacteria,COG2503@2|Bacteria,1U4Z7@1239|Firmicutes,24XAX@186801|Clostridia,36P30@31979|Clostridiaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_1702574_1	1537915.JU57_04045	3.8e-11	59.7	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
k59_1702574_2	1225785.CM001983_gene2655	6.47e-16	79.3	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,2JCW2@204037|Dickeya	1236|Gammaproteobacteria	F	dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs	dgt	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016462,GO:0016787,GO:0016788,GO:0016793,GO:0016817,GO:0016818,GO:0017111,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050897,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	iSF_1195.SF0152	HD,HD_assoc
k59_629438_1	1168067.JAGP01000001_gene1583	2.9e-40	148.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,45ZWJ@72273|Thiotrichales	72273|Thiotrichales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_629438_2	90814.KL370891_gene1648	4.42e-83	247.0	COG2365@1|root,COG2365@2|Bacteria,1REIM@1224|Proteobacteria	1224|Proteobacteria	T	Protein tyrosine serine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF442,Y_phosphatase2,Y_phosphatase3
k59_799031_1	1123514.KB905899_gene2044	1.65e-68	213.0	COG4232@1|root,COG4232@2|Bacteria,1N90P@1224|Proteobacteria,1SFPD@1236|Gammaproteobacteria,462UN@72273|Thiotrichales	72273|Thiotrichales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_799031_2	90814.KL370891_gene10	3.86e-205	576.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,45ZX9@72273|Thiotrichales	72273|Thiotrichales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_290419_1	1121011.AUCB01000005_gene2286	1.59e-07	58.5	COG5295@1|root,COG5295@2|Bacteria,4PI2R@976|Bacteroidetes,1IGAF@117743|Flavobacteriia,23IAY@178469|Arenibacter	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_686324_1	563040.Saut_1351	1.2e-34	130.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PMU@68525|delta/epsilon subdivisions,2YNHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k59_460202_1	305700.B447_12544	3.48e-11	62.4	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,2KUHJ@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_460202_2	547045.NEISICOT_02069	3.41e-45	160.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,2KPWD@206351|Neisseriales	206351|Neisseriales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1532514_1	649747.HMPREF0083_00983	1.15e-56	192.0	28MDY@1|root,30ACE@2|Bacteria,1UHM0@1239|Firmicutes,4HRIF@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177841_1	317025.Tcr_1943	2.18e-79	252.0	28J26@1|root,2Z8YT@2|Bacteria,1R7S5@1224|Proteobacteria,1RNDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
k59_177841_2	90813.JQMT01000001_gene1886	2.88e-38	137.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,4605U@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_1702590_1	563040.Saut_0893	1.01e-102	300.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2YNVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1702590_2	929558.SMGD1_0163	5.97e-25	98.2	COG4976@1|root,COG4976@2|Bacteria,1QZ2B@1224|Proteobacteria,43CEI@68525|delta/epsilon subdivisions,2YPR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_1419993_1	929558.SMGD1_2649	2.98e-160	469.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_686350_1	1121931.AUHG01000011_gene1758	4.75e-87	276.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1137244_1	1123518.ARWI01000001_gene388	5.03e-113	347.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,461R1@72273|Thiotrichales	72273|Thiotrichales	O	Belongs to the peptidase S16 family	-	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_403557_1	247490.KSU1_B0451	2.61e-21	90.9	292MF@1|root,2ZQ5C@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
k59_1532543_1	1123514.KB905899_gene525	8.55e-48	160.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,461AJ@72273|Thiotrichales	72273|Thiotrichales	P	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_1532543_2	90814.KL370891_gene1552	4.4e-58	206.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,dCache_1
k59_1702629_1	1120963.KB894496_gene2675	5.06e-07	52.4	2DS85@1|root,33EYM@2|Bacteria,1NJQN@1224|Proteobacteria,1SHH9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1137271_1	1565129.JSFF01000037_gene3000	3.76e-155	446.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,2Q9J3@267890|Shewanellaceae	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1420040_2	90814.KL370891_gene120	7.12e-74	234.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,46000@72273|Thiotrichales	72273|Thiotrichales	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_1025062_1	317025.Tcr_1879	1.77e-100	301.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,461U7@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_572939_1	411154.GFO_2255	6.31e-131	395.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_686417_1	929558.SMGD1_1946	1.37e-93	295.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_234411_1	1123518.ARWI01000001_gene2097	8.48e-172	489.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,45ZND@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1590088_1	563040.Saut_0602	2.02e-105	324.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2YMWR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1025112_1	563040.Saut_0322	2.02e-159	465.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_629587_1	506534.Rhein_3178	1.37e-22	88.2	COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria,1SGDV@1236|Gammaproteobacteria,1WZNH@135613|Chromatiales	135613|Chromatiales	K	PFAM Prophage CP4-57 regulatory	-	-	-	ko:K07733	-	-	-	-	ko00000,ko03000	-	-	-	Phage_AlpA
k59_629587_2	1111479.AXAR01000004_gene2134	0.000597	43.5	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,2780T@186823|Alicyclobacillaceae	91061|Bacilli	E	Aminotransferase class-V	nifZ	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_516111_1	1249997.JHZW01000003_gene3078	3.71e-25	110.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1HXNC@117743|Flavobacteriia,2PIG3@252356|Maribacter	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_1137356_1	1172190.M947_09145	3.5e-15	70.9	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1137356_2	929558.SMGD1_2268	7.86e-82	246.0	COG0711@1|root,COG0711@2|Bacteria,1Q9TP@1224|Proteobacteria,42U87@68525|delta/epsilon subdivisions,2YPT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1137356_3	563040.Saut_0773	9.83e-24	95.1	COG0712@1|root,COG0712@2|Bacteria,1RFPY@1224|Proteobacteria,42SKR@68525|delta/epsilon subdivisions,2YPHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1025130_1	867900.Celly_0424	2.2e-123	378.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia,1F8XQ@104264|Cellulophaga	976|Bacteroidetes	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_854863_1	317025.Tcr_0415	5.05e-29	108.0	2DQP1@1|root,337V6@2|Bacteria,1NBE8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_854863_2	317025.Tcr_0416	1.6e-62	203.0	COG1477@1|root,COG1477@2|Bacteria,1QTMG@1224|Proteobacteria,1S9F9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1362900_1	90814.KL370891_gene121	3.7e-64	210.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales	72273|Thiotrichales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF229,HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
k59_799206_1	1172190.M947_03620	5.56e-53	175.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2YMTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_799206_2	326298.Suden_1607	2.09e-23	96.3	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2YNAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1759459_1	929558.SMGD1_1902	1.24e-142	415.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_1759459_2	563040.Saut_1665	4.58e-45	148.0	COG0816@1|root,COG0816@2|Bacteria,1RJ6T@1224|Proteobacteria,42UR4@68525|delta/epsilon subdivisions,2YSYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_1702745_1	985255.APHJ01000040_gene356	2.66e-35	129.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1HXN1@117743|Flavobacteriia,2P5V2@244698|Gillisia	976|Bacteroidetes	S	GTP1/OBG	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_1702745_2	192952.MM_3198	2.72e-28	113.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
k59_1193462_1	76114.ebA2811	1.23e-74	246.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV2U@206389|Rhodocyclales	206389|Rhodocyclales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_7,PAS_8,PAS_9
k59_801159_1	457570.Nther_1125	1.33e-45	163.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
k59_574938_3	1028806.GGE_1985	4.43e-27	120.0	COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,1T0PY@1236|Gammaproteobacteria,1Y9IQ@135625|Pasteurellales	135625|Pasteurellales	S	Protein of unknown function (DUF1073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1073
k59_856796_1	1123514.KB905899_gene912	6.06e-77	236.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,1SYJC@1236|Gammaproteobacteria,4607A@72273|Thiotrichales	72273|Thiotrichales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_856796_2	90814.KL370891_gene1171	9.87e-72	219.0	COG2258@1|root,COG2258@2|Bacteria,1PBZ2@1224|Proteobacteria,1S8N6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_1544928_1	1123514.KB905899_gene1045	4.6e-161	474.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1037775_2	439235.Dalk_4072	6.82e-20	90.5	COG1235@1|root,COG3437@1|root,COG1235@2|Bacteria,COG3437@2|Bacteria,1R4W2@1224|Proteobacteria,43CSC@68525|delta/epsilon subdivisions,2X7ZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_1263407_1	83406.HDN1F_02470	6.39e-47	170.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J7N8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_1263407_2	1123517.JOMR01000001_gene1673	4.11e-29	112.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,460F1@72273|Thiotrichales	72273|Thiotrichales	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k59_529348_1	1380600.AUYN01000009_gene1557	3.51e-127	369.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_529348_2	1123057.P872_09905	4.08e-22	89.4	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,47QKW@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
k59_78283_1	177439.DP1189	1.45e-38	144.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,43B17@68525|delta/epsilon subdivisions,2X6FE@28221|Deltaproteobacteria,2MNE1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_359021_2	313595.P700755_002828	4.79e-27	106.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	MORN,MORN_2
k59_1321355_1	1123248.KB893331_gene3739	6.16e-19	91.7	COG3291@1|root,COG4257@1|root,COG3291@2|Bacteria,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF4082,DUF5011,GSDH,PKD,ThuA
k59_1321367_1	1353528.DT23_06695	5.21e-104	303.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,2XMZN@285107|Thioclava	28211|Alphaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_977465_1	1123234.AUKI01000015_gene2264	5.36e-57	182.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,1I39D@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	KOW,NusG
k59_1093117_1	90814.KL370891_gene1759	7.6e-97	294.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,45ZP3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_1544969_2	90814.KL370891_gene75	5.39e-228	630.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,4603B@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_1544969_3	90814.KL370891_gene74	4e-38	138.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4602X@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_247775_1	62928.azo1259	1.73e-93	286.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,2VHR4@28216|Betaproteobacteria,2KUIV@206389|Rhodocyclales	206389|Rhodocyclales	E	Peptidase dimerisation domain	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1149498_1	1502851.FG93_05938	2.97e-42	152.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,3JRWV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_191170_2	563040.Saut_1366	3.69e-50	161.0	COG1393@1|root,COG1393@2|Bacteria,1QA5B@1224|Proteobacteria,42UFC@68525|delta/epsilon subdivisions,2YPVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_191170_3	985867.AEWF01000006_gene588	3.04e-07	51.6	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2UBSZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_191170_4	929558.SMGD1_2439	2.87e-15	72.8	COG4649@1|root,COG4649@2|Bacteria,1Q2HI@1224|Proteobacteria,42VQJ@68525|delta/epsilon subdivisions,2YQ7B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_642905_1	563040.Saut_1457	9.54e-89	270.0	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,42QUG@68525|delta/epsilon subdivisions,2YP2D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
k59_1093134_2	1121931.AUHG01000012_gene2658	5.86e-52	179.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_977478_1	1197477.IA57_04415	2.64e-22	94.7	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_977478_2	1120951.AUBG01000006_gene519	1.42e-150	431.0	COG0596@1|root,COG0596@2|Bacteria,4NZUP@976|Bacteroidetes,1HZ6I@117743|Flavobacteriia	976|Bacteroidetes	S	Releases the N-terminal proline from various substrates	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_1149506_1	1537917.JU82_09430	1.2e-145	418.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2YMQU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_1149506_2	929558.SMGD1_2248	7.24e-48	155.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2YPV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase assembly chaperone HypC	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_1149506_3	326298.Suden_1430	9.35e-45	151.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2YMJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KO	Hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_1490065_1	929558.SMGD1_1620	6.67e-69	217.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2YMMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_1321408_1	1172190.M947_06155	1.08e-77	244.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2YMM3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	molybdopterin biosynthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1659608_1	637905.SVI_2370	1.82e-47	169.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,2Q90E@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
k59_529418_1	90814.KL370891_gene591	6.93e-20	84.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,1S8NW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport	exbB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_529418_2	1123514.KB905899_gene1526	4.69e-41	139.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,1SCA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	exbD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_812772_2	555500.I215_01530	6.41e-201	580.0	COG3866@1|root,COG4677@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,1IK65@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
k59_812772_3	1121887.AUDK01000001_gene462	8.47e-38	140.0	2C0TP@1|root,2Z7QF@2|Bacteria,4NGXF@976|Bacteroidetes,1HYWB@117743|Flavobacteriia,2NU72@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF5123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4957,DUF5123,fn3
k59_1263495_1	1380600.AUYN01000012_gene2964	1.03e-73	234.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1HWNP@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
k59_754705_1	323850.Shew_2739	3.3e-104	317.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,1RSN2@1236|Gammaproteobacteria,2QAQP@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
k59_473734_1	1123518.ARWI01000001_gene577	5.61e-37	139.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4604W@72273|Thiotrichales	72273|Thiotrichales	D	cell division protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_473734_2	90814.KL370891_gene735	2.54e-77	237.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,460XC@72273|Thiotrichales	72273|Thiotrichales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_642969_1	1484460.JSWG01000009_gene428	1.31e-78	240.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1HY9J@117743|Flavobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_642969_2	1380600.AUYN01000006_gene574	8.42e-66	201.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
k59_868373_1	1123518.ARWI01000001_gene526	3.55e-103	309.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,4609Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_1037910_1	1123228.AUIH01000005_gene647	1.35e-53	188.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XIVR@135619|Oceanospirillales	135619|Oceanospirillales	KL	helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_1149573_1	411154.GFO_2994	1.08e-180	512.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HZKA@117743|Flavobacteriia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_868391_1	1197477.IA57_07470	3.02e-40	145.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1HWYT@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_868391_2	1380600.AUYN01000001_gene2275	8.6e-58	194.0	COG2244@1|root,COG2244@2|Bacteria,4NHYC@976|Bacteroidetes,1HWN7@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_868399_1	637905.SVI_2626	1.25e-46	160.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,2QBBS@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Phenazine biosynthesis-like protein	pab	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k59_20023_2	504487.JCM19302_1878	9.79e-121	349.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1093232_1	929558.SMGD1_2673	1.41e-114	334.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2YMJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_585844_2	944547.ABLL_1812	8.66e-50	162.0	COG1433@1|root,COG1433@2|Bacteria,1P8Y4@1224|Proteobacteria,42VVM@68525|delta/epsilon subdivisions,2YQI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_416742_1	313595.P700755_003422	1.16e-115	360.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,4C3DT@83612|Psychroflexus	976|Bacteroidetes	V	MMPL family	mexF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_643052_1	1123228.AUIH01000002_gene1452	3.13e-106	318.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XHQS@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_78482_1	1453498.LG45_14445	1.07e-22	95.5	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I20T@117743|Flavobacteriia,2P071@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
k59_78482_2	984262.SGRA_2329	2.62e-16	76.3	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1IRYX@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_191327_1	983544.Lacal_2229	3.53e-91	273.0	COG1266@1|root,COG1266@2|Bacteria,4NMYM@976|Bacteroidetes,1I2NV@117743|Flavobacteriia	976|Bacteroidetes	S	Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
k59_1603933_2	563040.Saut_1939	1.41e-129	374.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_1603939_1	1392498.JQLH01000001_gene3609	1.22e-50	176.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2PG19@252356|Maribacter	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1490233_2	1406840.Q763_09750	1.47e-90	268.0	COG0497@1|root,COG0497@2|Bacteria,4NN6W@976|Bacteroidetes,1IJ34@117743|Flavobacteriia,2P0IJ@237|Flavobacterium	976|Bacteroidetes	L	DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20083_1	326298.Suden_1909	9.81e-44	150.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2YMYB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_20083_2	929558.SMGD1_1559	9.18e-106	309.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2YMQX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1772996_1	1120951.AUBG01000005_gene2177	8.82e-132	381.0	28KQN@1|root,2ZA8E@2|Bacteria,4NID0@976|Bacteroidetes,1HYPC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_700366_1	572477.Alvin_0474	2.27e-51	173.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RY2H@1236|Gammaproteobacteria,1WX0H@135613|Chromatiales	135613|Chromatiales	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_1149683_1	563040.Saut_0079	8.66e-88	264.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_1434981_1	1172190.M947_02860	4.08e-63	203.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1434981_2	1355374.JARU01000018_gene2016	1.9e-12	67.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2YMW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_306347_1	1172190.M947_10745	3.58e-64	212.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1095730_1	1172190.M947_06905	9.68e-106	312.0	COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,42ZNV@68525|delta/epsilon subdivisions,2YRNU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1492825_1	411154.GFO_2975	1.98e-99	309.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_1718552_2	1380600.AUYN01000001_gene2378	2.14e-60	198.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1HWJF@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_306366_1	1137281.D778_00614	6.05e-156	457.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_645392_1	981336.F944_02146	3.84e-15	76.6	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,3NIW7@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	yiaD	-	-	ko:K12216	-	-	-	-	ko00000,ko02044	3.A.7.9.1	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
k59_645392_2	317025.Tcr_0209	7.75e-97	288.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,460IJ@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_645392_3	1123518.ARWI01000001_gene1132	9.6e-44	158.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1QVWQ@1224|Proteobacteria,1T2KZ@1236|Gammaproteobacteria,463U0@72273|Thiotrichales	72273|Thiotrichales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_1662215_1	868131.MSWAN_1217	4.88e-78	254.0	COG2217@1|root,arCOG01576@2157|Archaea,2XT3T@28890|Euryarchaeota,23NJY@183925|Methanobacteria	183925|Methanobacteria	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_1152149_1	1123514.KB905902_gene285	1.97e-100	302.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluF	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.21	ko:K06182,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1152149_2	1123514.KB905902_gene209	8.11e-54	178.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,4621W@72273|Thiotrichales	72273|Thiotrichales	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_250531_1	319224.Sputcn32_2898	1.23e-13	64.3	2E35B@1|root,32Y5A@2|Bacteria,1N850@1224|Proteobacteria,1SCFH@1236|Gammaproteobacteria,2QE65@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_250531_2	319224.Sputcn32_2899	5.49e-38	127.0	COG3655@1|root,COG3655@2|Bacteria,1NA11@1224|Proteobacteria,1SD6H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
k59_1378237_1	90814.KL370892_gene2194	7.11e-64	200.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,460R5@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_1378237_2	1123518.ARWI01000001_gene1494	0.0	970.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,4604K@72273|Thiotrichales	72273|Thiotrichales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_419261_1	945713.IALB_0909	6.57e-08	53.1	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_419263_1	631362.Thi970DRAFT_01249	5.21e-32	125.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1WWBP@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07814,ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,Response_reg
k59_193860_1	1380600.AUYN01000009_gene1307	5.81e-137	413.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_638748_1	929558.SMGD1_1780	1.38e-30	109.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_638748_2	929558.SMGD1_1781	6.24e-129	387.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_129649_1	1348657.M622_05555	1.44e-68	219.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,2VH4R@28216|Betaproteobacteria,2KWA6@206389|Rhodocyclales	206389|Rhodocyclales	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
k59_412516_1	945713.IALB_3147	8.23e-98	308.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02336,ko:K06877,ko:K07501	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1
k59_187154_1	90814.KL370891_gene1159	6e-33	128.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,45ZMI@72273|Thiotrichales	72273|Thiotrichales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_187154_2	90814.KL370891_gene1158	1.65e-86	260.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,45ZPM@72273|Thiotrichales	72273|Thiotrichales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_243625_1	504487.JCM19302_4119	1.82e-19	84.0	COG2825@1|root,COG2825@2|Bacteria,4NN8F@976|Bacteroidetes,1I21G@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_864178_1	1565129.JSFF01000031_gene2982	3.95e-106	310.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria,2QAAR@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	napG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
k59_638772_1	1121931.AUHG01000011_gene1914	1.26e-68	231.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
k59_1371703_1	1469557.JSWF01000028_gene2995	2.95e-53	181.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,1HWTA@117743|Flavobacteriia	976|Bacteroidetes	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_1541289_1	880070.Cycma_0047	9.06e-200	574.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_1485953_1	1392490.JHZX01000001_gene2848	1.13e-16	73.9	COG4980@1|root,COG4980@2|Bacteria,4NRSE@976|Bacteroidetes,1I46Y@117743|Flavobacteriia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
k59_1485953_2	1347342.BN863_13760	1.59e-76	230.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,1I1ZU@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_864194_1	1239962.C943_00064	6.26e-36	126.0	COG4319@1|root,COG4319@2|Bacteria,4NUN7@976|Bacteroidetes,47WZP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k59_187189_1	1120951.AUBG01000005_gene2220	3.03e-18	77.4	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,1I3YR@117743|Flavobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_187189_2	504487.JCM19302_1598	6.14e-64	203.0	28HPY@1|root,2Z7XS@2|Bacteria,4NJIW@976|Bacteroidetes,1HZBP@117743|Flavobacteriia	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
k59_187189_3	1178825.ALIH01000006_gene1554	5.21e-42	148.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1I0Y1@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
k59_920294_1	132113.XP_003494847.1	2.56e-78	259.0	COG0442@1|root,COG0642@1|root,KOG0519@2759|Eukaryota,KOG2324@2759|Eukaryota,38HAU@33154|Opisthokonta,3BD03@33208|Metazoa,3CSIY@33213|Bilateria,41XHG@6656|Arthropoda,3SGR7@50557|Insecta,46JGQ@7399|Hymenoptera	33208|Metazoa	J	Anticodon binding domain	-	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_74131_1	351746.Pput_3909	4.63e-11	63.5	COG1212@1|root,COG1778@1|root,COG1212@2|Bacteria,COG1778@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1YXAI@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
k59_1198551_1	1178825.ALIH01000019_gene1234	6.69e-12	64.7	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_1198551_2	983544.Lacal_0338	8.51e-46	162.0	298D5@1|root,30PYQ@2|Bacteria,4NNR2@976|Bacteroidetes,1I21A@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
k59_243681_2	224911.27353818	3.07e-13	70.5	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JQV4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase	MA20_31570	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_7,PAS_8
k59_243685_1	1121931.AUHG01000011_gene2226	4.73e-115	353.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_750941_2	497321.C664_18534	8.38e-90	287.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,2KU82@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_469559_1	709032.Sulku_1670	1.37e-19	86.3	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	709032.Sulku_1670|-	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_469559_2	41431.PCC8801_1483	1.94e-27	118.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,1GPY5@1117|Cyanobacteria	1117|Cyanobacteria	T	Regulator	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k59_1317244_1	572480.Arnit_2663	8.18e-30	117.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_641393_1	555500.I215_06252	1.12e-62	200.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1HWKD@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM aldo keto reductase	gpr	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
k59_641393_2	1121931.AUHG01000012_gene2498	2.15e-65	203.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
k59_415020_3	743720.Psefu_1423	1.25e-78	257.0	COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria,1YW7N@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	C-5 cytosine-specific DNA methylase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_132053_1	709032.Sulku_2359	4.51e-93	277.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2YN0R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_132053_2	929558.SMGD1_1504	6.25e-141	402.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2YMDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_76893_1	1123518.ARWI01000001_gene453	2.59e-40	142.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,4625S@72273|Thiotrichales	72273|Thiotrichales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_76893_2	90814.KL370891_gene837	6.23e-154	438.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,460FP@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_76893_3	888064.HMPREF9088_0094	1.25e-09	58.5	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,4AZ5V@81852|Enterococcaceae	91061|Bacilli	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1658086_1	1178825.ALIH01000010_gene478	1.43e-202	575.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1HX1R@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_1658088_1	1565129.JSFF01000004_gene3190	3.11e-86	263.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,2QA8V@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_132062_1	398720.MED217_16145	7.78e-45	163.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HXVC@117743|Flavobacteriia,2XJ3U@283735|Leeuwenhoekiella	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
k59_1431182_1	572480.Arnit_0854	2.28e-32	115.0	2EQTE@1|root,33ID4@2|Bacteria,1RKB7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1431182_2	572480.Arnit_0853	7.14e-70	214.0	COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,42TEB@68525|delta/epsilon subdivisions,2YP5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1658095_1	563040.Saut_1367	9.6e-26	103.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1658095_2	87626.PTD2_17042	3.25e-26	110.0	COG2199@1|root,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria,2Q01E@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	rrpX	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_76905_1	746697.Aeqsu_1462	8.32e-105	318.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_1200446_1	1165841.SULAR_00135	5.16e-137	407.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1374313_1	1392488.JHZY01000002_gene324	1.25e-30	118.0	COG1714@1|root,COG1714@2|Bacteria,4NW7A@976|Bacteroidetes,1I578@117743|Flavobacteriia,2XK7J@283735|Leeuwenhoekiella	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_189726_1	1492738.FEM21_02550	6.39e-18	83.6	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia,2NTAE@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
k59_189726_2	1392488.JHZY01000004_gene2527	5.17e-259	714.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1IEAI@117743|Flavobacteriia,2XKC7@283735|Leeuwenhoekiella	976|Bacteroidetes	H	C-5 cytosine-specific DNA methylase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_189726_3	555500.I215_09376	1.44e-248	690.0	28JKN@1|root,2Z9DE@2|Bacteria,4NH4D@976|Bacteroidetes,1HWN9@117743|Flavobacteriia	976|Bacteroidetes	S	MvaI/BcnI restriction endonuclease family	-	-	-	-	-	-	-	-	-	-	-	-	MvaI_BcnI
k59_698639_1	983548.Krodi_0973	1.36e-27	111.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia,37DMC@326319|Dokdonia	976|Bacteroidetes	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_698639_2	985255.APHJ01000021_gene1544	1.23e-37	137.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2P6KC@244698|Gillisia	976|Bacteroidetes	EH	Acetohydroxy acid isomeroreductase, NADPH-binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1543645_1	318167.Sfri_2090	2.19e-84	280.0	COG0470@1|root,COG0470@2|Bacteria,1MVEE@1224|Proteobacteria,1S0R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1543645_2	318167.Sfri_2091	1.78e-54	177.0	COG0175@1|root,COG0175@2|Bacteria,1R52W@1224|Proteobacteria,1RRZS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
k59_1771298_1	1123518.ARWI01000001_gene304	1.4e-289	823.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,4602D@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1200459_1	929558.SMGD1_1808	5.4e-70	225.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_866845_1	1121931.AUHG01000010_gene563	2.18e-113	329.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_811092_1	1270193.JARP01000001_gene2532	3.54e-28	107.0	COG0580@1|root,COG0580@2|Bacteria,4NFW4@976|Bacteroidetes,1HXX1@117743|Flavobacteriia,2NSF5@237|Flavobacterium	976|Bacteroidetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
k59_811092_2	1197477.IA57_08035	4.56e-39	130.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,1I51R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_811092_3	1347342.BN863_5170	2.27e-05	45.4	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_1262042_1	1122179.KB890469_gene599	3.2e-68	232.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1714755_2	1121931.AUHG01000010_gene565	3.22e-24	98.6	COG0524@1|root,COG0524@2|Bacteria,4NJIK@976|Bacteroidetes,1I00V@117743|Flavobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1602155_1	504487.JCM19302_3690	4.68e-120	358.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_866873_1	929558.SMGD1_1780	1.74e-13	65.1	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_866873_2	563040.Saut_0523	5.85e-67	218.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2J@1224|Proteobacteria,42UFK@68525|delta/epsilon subdivisions,2YQ0J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1658171_1	1123518.ARWI01000001_gene160	4.9e-97	296.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,460QB@72273|Thiotrichales	72273|Thiotrichales	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_1148237_1	338966.Ppro_1293	1.71e-43	153.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria,43T7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1148237_2	443143.GM18_2265	4.84e-51	169.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
k59_528013_1	985255.APHJ01000027_gene813	9.72e-134	388.0	COG3489@1|root,COG3489@2|Bacteria,4NFAT@976|Bacteroidetes,1HXCH@117743|Flavobacteriia,2P78K@244698|Gillisia	976|Bacteroidetes	S	Imelysin	-	-	-	ko:K07338	-	-	-	-	ko00000	-	-	-	Peptidase_M75
k59_1488595_1	1123514.KB905902_gene303	5.69e-105	323.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria,460C0@72273|Thiotrichales	72273|Thiotrichales	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_1488595_2	1163409.UUA_11001	3.8e-07	51.2	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1X4D6@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_1374383_1	90814.KL370891_gene1357	2.2e-20	87.0	28M4C@1|root,2ZAIA@2|Bacteria,1R67D@1224|Proteobacteria,1RQQQ@1236|Gammaproteobacteria,460BT@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_1374383_2	225937.HP15_855	3.01e-41	152.0	COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria,1SB0F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,UT
k59_753377_1	504487.JCM19302_66	5.11e-78	239.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
k59_753377_2	391603.FBALC1_10317	9.08e-139	398.0	28PKM@1|root,2ZCA0@2|Bacteria,4NHEG@976|Bacteroidetes,1I1K5@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
k59_584462_1	1202532.FF52_16923	1.12e-95	299.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_584462_2	1270193.JARP01000006_gene1737	1.76e-42	152.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1HWTC@117743|Flavobacteriia,2NV3H@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1488614_1	1055815.AYYA01000039_gene95	5.64e-73	228.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
k59_1200520_1	572480.Arnit_1361	4.97e-137	402.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_753392_1	1168034.FH5T_15665	2.66e-289	819.0	COG3250@1|root,COG3250@2|Bacteria,4NK0C@976|Bacteroidetes,2FQSH@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_698736_1	1123514.KB905903_gene381	1.21e-105	310.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,4602G@72273|Thiotrichales	72273|Thiotrichales	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_698736_2	1123518.ARWI01000001_gene1788	3.07e-149	423.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,46143@72273|Thiotrichales	72273|Thiotrichales	S	membrane transporter protein	-	-	-	ko:K07090,ko:K11312	-	-	-	-	ko00000	-	-	-	TauE
k59_698736_3	926559.JoomaDRAFT_1127	5.18e-26	107.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_302494_1	411154.GFO_1754	1.53e-105	310.0	COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1HWKN@117743|Flavobacteriia	976|Bacteroidetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_1374411_1	411154.GFO_3397	5.91e-94	284.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,1HWZ5@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_472417_1	1270193.JARP01000006_gene1735	3.32e-40	142.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia,2NSGH@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_472417_2	376686.Fjoh_2032	8.11e-97	303.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_77033_1	945713.IALB_2645	1.19e-113	350.0	COG0495@1|root,COG0495@2|Bacteria	2|Bacteria	J	leucyl-tRNA aminoacylation	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_641548_1	1121931.AUHG01000010_gene600	6.46e-156	449.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_753407_1	90814.KL370891_gene632	8.64e-111	332.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,45ZYV@72273|Thiotrichales	72273|Thiotrichales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_1543752_1	360107.CHAB381_A0005	8.51e-49	173.0	2AQWX@1|root,2ZYSX@2|Bacteria,1QYQR@1224|Proteobacteria,43CI2@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
k59_376172_4	1406840.Q763_09665	3.59e-62	195.0	COG0518@1|root,COG0518@2|Bacteria,4NMFC@976|Bacteroidetes,1ID0Q@117743|Flavobacteriia,2NWQD@237|Flavobacterium	976|Bacteroidetes	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k59_1213145_1	323850.Shew_1418	6.92e-31	116.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,2QB4S@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1213145_2	754436.JCM19237_3997	1.93e-86	263.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1XU3P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1508059_2	572480.Arnit_0111	2.28e-123	370.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,MASE2,PAS_7
k59_1733178_1	563040.Saut_0003	8.33e-113	345.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1167447_1	326298.Suden_1181	1.2e-83	257.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2YM99@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_719064_1	1121931.AUHG01000011_gene1660	5.01e-82	275.0	COG4886@1|root,COG4932@1|root,COG4935@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_1508083_1	748247.AZKH_3617	9.19e-99	305.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,2KUED@206389|Rhodocyclales	206389|Rhodocyclales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_321306_1	1121931.AUHG01000019_gene3039	8.44e-100	311.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia	976|Bacteroidetes	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
k59_1621353_1	1249975.JQLP01000001_gene2810	2.9e-26	112.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2P78E@244698|Gillisia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_95527_1	1121931.AUHG01000017_gene1504	1.87e-192	551.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_993550_1	944547.ABLL_2785	1.63e-44	164.0	COG3287@1|root,COG3437@1|root,COG3287@2|Bacteria,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
k59_721886_2	1397528.Q671_11320	4.84e-06	47.8	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1XI8U@135619|Oceanospirillales	135619|Oceanospirillales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_1452259_2	1166018.FAES_4690	6.98e-71	221.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,47PEA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_324088_1	504487.JCM19302_1047	1.53e-83	262.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1HWV6@117743|Flavobacteriia	976|Bacteroidetes	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_603864_1	1121931.AUHG01000010_gene572	1.24e-10	60.5	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_1215546_2	563040.Saut_1005	1.22e-88	269.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2YMJB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_211272_1	929558.SMGD1_0343	4.43e-123	362.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1510895_1	28258.KP05_13265	5.74e-51	176.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XHN7@135619|Oceanospirillales	135619|Oceanospirillales	S	Tripartite tricarboxylate transporter TctA	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k59_211273_1	1123518.ARWI01000001_gene1523	7.9e-156	459.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales	72273|Thiotrichales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1170205_1	1123326.JFBL01000022_gene2618	1.17e-57	196.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_324133_1	1178825.ALIH01000012_gene1819	1.93e-80	258.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia	976|Bacteroidetes	EM	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
k59_98381_1	1380600.AUYN01000009_gene1778	3.24e-112	328.0	COG5343@1|root,COG5343@2|Bacteria,4NH0S@976|Bacteroidetes,1HY07@117743|Flavobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
k59_1679606_1	929558.SMGD1_1870	9.28e-159	473.0	COG2199@1|root,COG2200@1|root,COG4753@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,COG4753@2|Bacteria,1R7HC@1224|Proteobacteria,42RY7@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
k59_1679606_2	563040.Saut_1703	1.59e-85	254.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,42RGH@68525|delta/epsilon subdivisions,2YP5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_1679606_3	929558.SMGD1_1872	1.88e-15	74.7	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2YMIS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_721950_1	572480.Arnit_0715	4.98e-152	455.0	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1623552_1	563040.Saut_0896	7.64e-109	324.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_1623552_2	563040.Saut_0897	6.2e-78	241.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1215602_1	1168289.AJKI01000046_gene867	1.6e-118	361.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,2FX8W@200643|Bacteroidia,3XKI5@558415|Marinilabiliaceae	976|Bacteroidetes	P	haloacid dehalogenase-like hydrolase	copB	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_1283534_1	595460.RRSWK_05943	2.57e-09	62.8	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,HisKA_7TM,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_1283534_2	637905.SVI_2173	5.02e-06	49.3	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1NC9X@1224|Proteobacteria,1T1YW@1236|Gammaproteobacteria,2Q90W@267890|Shewanellaceae	1236|Gammaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
k59_1736000_1	1123514.KB905900_gene2210	9.32e-17	75.5	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,460PM@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_1736000_2	1123514.KB905900_gene2211	2.26e-106	311.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,460JB@72273|Thiotrichales	72273|Thiotrichales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_1736000_3	1123514.KB905900_gene2212	4.19e-106	316.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_996279_1	563040.Saut_1720	2.83e-22	88.2	2AK8C@1|root,31AYM@2|Bacteria,1Q6J3@1224|Proteobacteria,43398@68525|delta/epsilon subdivisions,2YSRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_996279_2	563040.Saut_1721	2.59e-134	382.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_1283535_3	1150621.SMUL_0005	6.24e-71	215.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2YP5I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_1283535_4	929558.SMGD1_1249	1.54e-14	72.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1170260_1	1137281.D778_00535	9.8e-76	235.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1HX5R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1170260_2	391603.FBALC1_12387	6.58e-74	229.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1HY13@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_941940_1	938289.CAJN020000006_gene443	3.65e-17	73.9	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia	186801|Clostridia	C	rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
k59_941940_2	639282.DEFDS_0706	1.47e-16	78.6	COG0672@1|root,COG0672@2|Bacteria,2GGKP@200930|Deferribacteres	200930|Deferribacteres	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
k59_1215641_1	411154.GFO_1949	6.63e-89	265.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1HY18@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1215641_2	411154.GFO_1948	9.51e-104	305.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1HYXD@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
k59_1679656_1	28229.ND2E_3408	2.73e-49	180.0	COG1629@1|root,COG4771@2|Bacteria,1R4PY@1224|Proteobacteria,1RYVW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k59_1452370_1	1163617.SCD_n02696	2.23e-20	90.1	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_1452370_2	397945.Aave_4209	7.98e-20	84.3	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,4ADZP@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Thioredoxin domain	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_1510986_1	411154.GFO_2769	5.4e-192	540.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1056119_1	572480.Arnit_3004	1.09e-175	494.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2YN2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	iIT341.HP0867	LpxB
k59_1056119_2	572480.Arnit_3005	1.09e-76	230.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2YP5R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_436882_1	1298593.TOL_0827	1.56e-42	144.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XJ8C@135619|Oceanospirillales	135619|Oceanospirillales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_436882_2	498211.CJA_0643	2.12e-11	62.8	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1FGR8@10|Cellvibrio	1236|Gammaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_1623601_1	985255.APHJ01000040_gene338	2.15e-67	223.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1HWZF@117743|Flavobacteriia,2P76J@244698|Gillisia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_1452393_1	1168067.JAGP01000001_gene568	2.05e-58	192.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_1793355_1	945713.IALB_0303	5.54e-25	103.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,HAMP,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1793355_2	203119.Cthe_1267	1.03e-18	84.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WHYU@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_153604_1	411154.GFO_3338	1.93e-86	258.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia	976|Bacteroidetes	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_493499_1	90814.KL370891_gene1388	1.05e-107	320.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_888409_1	365044.Pnap_2038	1.49e-34	122.0	COG1433@1|root,COG1433@2|Bacteria,1RIKC@1224|Proteobacteria,2VSNY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k59_1565363_1	1172190.M947_08060	9.79e-103	310.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YMXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_722085_1	944547.ABLL_2061	2.52e-35	125.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,42MBG@68525|delta/epsilon subdivisions,2YMHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.30,3.2.2.9	ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_98537_1	1123518.ARWI01000001_gene2220	1.18e-110	333.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4604A@72273|Thiotrichales	72273|Thiotrichales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_324298_1	1127673.GLIP_3561	8.1e-08	58.9	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,464I6@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	cvaB	-	-	ko:K06147,ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding
k59_1215744_1	391587.KAOT1_06252	6.68e-31	118.0	COG1083@1|root,COG1083@2|Bacteria,4NM98@976|Bacteroidetes,1I17Z@117743|Flavobacteriia	976|Bacteroidetes	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_1215744_2	614083.AWQR01000001_gene3071	7.07e-74	228.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,4ABNW@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_1215744_3	118161.KB235919_gene6378	1.09e-62	213.0	COG0517@1|root,COG1082@1|root,COG2089@1|root,COG0517@2|Bacteria,COG1082@2|Bacteria,COG2089@2|Bacteria,1G4IG@1117|Cyanobacteria,3VM4T@52604|Pleurocapsales	1117|Cyanobacteria	GM	Xylose isomerase-like TIM barrel	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,CBS,NeuB,SAF
k59_379085_1	1484460.JSWG01000006_gene3028	0.000647	47.8	COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3866@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
k59_548047_1	411154.GFO_2876	1.89e-34	126.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1HX81@117743|Flavobacteriia	976|Bacteroidetes	I	synthase	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_548047_2	1121931.AUHG01000011_gene1646	2.44e-113	326.0	COG2227@1|root,COG2227@2|Bacteria,4NM91@976|Bacteroidetes,1HZAR@117743|Flavobacteriia	976|Bacteroidetes	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1679757_1	929558.SMGD1_0132	8.32e-64	216.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03090,ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	CHASE,CheX,GAF,GGDEF,PAS_8,Response_reg,cNMP_binding
k59_1565458_1	1353528.DT23_15320	1.71e-71	229.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,2XKUI@285107|Thioclava	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_1565458_2	1353528.DT23_15325	2.44e-13	68.9	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TTN3@28211|Alphaproteobacteria,2XN23@285107|Thioclava	28211|Alphaproteobacteria	U	transporter, permease	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_888480_1	1406840.Q763_09595	1.23e-85	252.0	2CTAF@1|root,32SSZ@2|Bacteria,4NTNC@976|Bacteroidetes,1I8Q3@117743|Flavobacteriia,2P0D4@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_888480_2	655815.ZPR_3422	1.24e-210	588.0	COG3843@1|root,COG3843@2|Bacteria,4NG66@976|Bacteroidetes	976|Bacteroidetes	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
k59_663466_1	572480.Arnit_0523	5.29e-52	171.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2YMKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	fecE	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_663466_2	1304885.AUEY01000058_gene2306	5.5e-14	70.5	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_663480_1	561231.Pecwa_2942	7.46e-17	79.7	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,1MTF7@122277|Pectobacterium	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	ybhG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_663480_2	998674.ATTE01000001_gene4007	7.41e-32	125.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,463U2@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter	-	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
k59_153702_1	411154.GFO_1817	1.63e-161	467.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1565496_1	1116375.VEJY3_01105	6.15e-06	53.1	COG1835@1|root,COG1835@2|Bacteria,1RDQ4@1224|Proteobacteria,1S45C@1236|Gammaproteobacteria,1XZ0E@135623|Vibrionales	135623|Vibrionales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_996522_1	411154.GFO_2964	2.5e-62	196.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_996522_2	411154.GFO_2963	1.3e-32	125.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_1342463_1	1123514.KB905899_gene1973	2.65e-107	314.0	COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,461SZ@72273|Thiotrichales	72273|Thiotrichales	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
k59_463740_2	1380600.AUYN01000009_gene2047	3.81e-51	171.0	2C793@1|root,2Z9MK@2|Bacteria,4NI6K@976|Bacteroidetes,1HWYK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_1706002_1	411154.GFO_0018	7.62e-49	173.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
k59_181276_1	626887.J057_07386	1.69e-37	134.0	COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria,1SIPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_181276_2	28229.ND2E_2475	2.16e-28	105.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,2Q6TA@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Uncharacterized BCR, YaiI/YqxD family COG1671	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_858150_1	62928.azo0376	6.63e-86	273.0	COG0010@1|root,COG4992@1|root,COG0010@2|Bacteria,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KWDX@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,Arginase
k59_463760_1	411154.GFO_1762	2.03e-96	289.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1HYNA@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_802529_1	1218074.BAXZ01000002_gene242	1.12e-87	266.0	2ADRF@1|root,313GS@2|Bacteria,1PSE3@1224|Proteobacteria,2WA7A@28216|Betaproteobacteria,1K285@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1762736_1	1172190.M947_09990	6.89e-100	305.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1140382_1	326298.Suden_1045	3.97e-64	227.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_1535823_1	411154.GFO_2855	3.57e-37	135.0	290I6@1|root,2ZN71@2|Bacteria,4NM5S@976|Bacteroidetes,1I19E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1535823_2	411154.GFO_2854	1.18e-73	231.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_463792_1	1469557.JSWF01000025_gene1327	1.78e-55	176.0	295MU@1|root,2ZSZ8@2|Bacteria,4NP18@976|Bacteroidetes,1I1YU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_463792_2	1137281.D778_00455	2.27e-08	52.8	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1I202@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_519461_1	90814.KL370891_gene756	2.02e-79	239.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,460RV@72273|Thiotrichales	72273|Thiotrichales	T	Low molecular weight phosphotyrosine protein phosphatase	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_68119_1	387093.SUN_1373	9.55e-40	141.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2YNK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_68119_2	929558.SMGD1_1574	9.33e-135	406.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_293849_1	90813.JQMT01000001_gene686	2.74e-44	153.0	2EAP9@1|root,334RQ@2|Bacteria,1NDHV@1224|Proteobacteria,1SD8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_293849_2	1123514.KB905899_gene1636	2.54e-51	169.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,1RMCB@1236|Gammaproteobacteria,461PD@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_181335_1	1121931.AUHG01000012_gene2691	1.03e-91	279.0	COG1196@1|root,COG1196@2|Bacteria,4NIJ6@976|Bacteroidetes,1HZCG@117743|Flavobacteriia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_406951_1	411154.GFO_1951	1.61e-28	110.0	COG2207@1|root,COG2207@2|Bacteria,4NNDN@976|Bacteroidetes,1I1T3@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_406951_2	411154.GFO_1950	5.82e-220	630.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1HZCQ@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_237931_1	1122993.KB898325_gene2064	5.06e-60	211.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,4NJ3U@976|Bacteroidetes	976|Bacteroidetes	L	N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
k59_237937_2	411154.GFO_1017	4.99e-112	326.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1HXQW@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_1535857_2	929558.SMGD1_2472	7.23e-85	255.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_745414_1	1123518.ARWI01000001_gene887	8.87e-269	750.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1SYH1@1236|Gammaproteobacteria,45ZV2@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_858222_1	338966.Ppro_3460	5.17e-38	150.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,43AN8@68525|delta/epsilon subdivisions,2X62F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
k59_406967_1	90814.KL370891_gene666	7.19e-131	376.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,460DS@72273|Thiotrichales	72273|Thiotrichales	N	TIGRFAM flagellar basal-body rod protein FlgF	-	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1140427_1	1120951.AUBG01000006_gene525	2.41e-58	191.0	2E129@1|root,32WI1@2|Bacteria,4NSEA@976|Bacteroidetes,1I4QV@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
k59_1140427_2	1380600.AUYN01000003_gene14	8.23e-109	321.0	COG3631@1|root,COG3631@2|Bacteria,4NPKS@976|Bacteroidetes,1I2EQ@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	DUF4440,SnoaL,SnoaL_2
k59_1480013_1	1380600.AUYN01000009_gene1316	5.8e-73	228.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
k59_1593664_1	945713.IALB_1680	1.93e-76	248.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_802610_1	1380600.AUYN01000009_gene1217	1.03e-174	494.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_68163_2	247639.MGP2080_00345	2.2e-50	182.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria	1224|Proteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
k59_68163_3	1201293.AKXQ01000009_gene939	2.07e-11	63.9	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1706113_1	1123518.ARWI01000001_gene2464	8.07e-73	239.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,463KB@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_858243_2	652103.Rpdx1_1192	1.37e-25	105.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,3K48K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_1366142_1	90814.KL370892_gene2331	6.49e-39	140.0	COG2304@1|root,COG4254@1|root,COG2304@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
k59_1366142_2	90814.KL370891_gene1	3.7e-12	67.0	COG2304@1|root,COG2931@1|root,COG4254@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,HemolysinCabind,VWA_2
k59_1311274_1	411154.GFO_3634	4.07e-115	340.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia	976|Bacteroidetes	S	Flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1593678_1	1123514.KB905903_gene417	5.63e-56	187.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG3156 Type II secretory pathway component PulK	gspK	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_11055_1	1223410.KN050846_gene2314	2.21e-145	422.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_11055_2	1349785.BAUG01000023_gene1484	3.12e-308	858.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_237979_1	1336233.JAEH01000009_gene2742	8.56e-26	103.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,2Q8IU@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SMART transcription factor jumonji jmjC domain protein	ycfD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
k59_237979_2	1565129.JSFF01000014_gene351	6.48e-80	249.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,2Q8QB@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_1593687_1	1380600.AUYN01000006_gene562	3.05e-47	157.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia	976|Bacteroidetes	S	zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
k59_745453_1	1121939.L861_07305	3.43e-81	250.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,1XH8D@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1142431_2	388399.SSE37_03600	6.28e-56	180.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,2TUXH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_351756_1	90814.KL370891_gene1694	1.9e-31	112.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,46178@72273|Thiotrichales	72273|Thiotrichales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_409030_1	94122.Shewana3_3160	2.81e-27	112.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,2Q8YP@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_2885	ATP-grasp_3,Glu_cys_ligase
k59_409030_2	392500.Swoo_3325	5.07e-17	76.3	2ET0J@1|root,33KIS@2|Bacteria,1QVZD@1224|Proteobacteria,1T2P5@1236|Gammaproteobacteria,2QCBS@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_578664_1	1565129.JSFF01000015_gene36	2.76e-116	346.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,2QAN8@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM CBS domain containing protein	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_1765055_1	323850.Shew_2529	5.15e-78	249.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN61@1236|Gammaproteobacteria,2Q9K0@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM pseudouridine synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_183603_1	1397528.Q671_01440	1.7e-28	114.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1XHDB@135619|Oceanospirillales	135619|Oceanospirillales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.117	ko:K20455	ko00640,map00640	-	R11263	RC01152	ko00000,ko00001,ko01000	-	-	-	Aconitase,Aconitase_C
k59_183603_2	1121878.AUGL01000001_gene394	8.57e-60	195.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	protein conserved in bacteria	prpF	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0071704,GO:0072329,GO:1901575	-	ko:K09788	ko00640,map00640	-	R11264	RC03405	ko00000,ko00001,ko01000	-	-	-	PrpF
k59_465914_1	929558.SMGD1_0630	5.82e-94	290.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_465914_2	929558.SMGD1_0631	5.75e-44	148.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1651938_1	637905.SVI_2115	3.02e-90	265.0	COG0789@1|root,COG0789@2|Bacteria,1N4Q1@1224|Proteobacteria,1SEIH@1236|Gammaproteobacteria,2QCZ2@267890|Shewanellaceae	1236|Gammaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_409040_2	326298.Suden_2066	3.81e-41	139.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2YPUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_409040_3	367737.Abu_2277	3.59e-52	169.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2YMYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_916942_1	338963.Pcar_1098	5.81e-58	190.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,43UA7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1255775_1	1380600.AUYN01000001_gene2911	2.33e-19	81.6	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1I1XW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1255775_2	1380600.AUYN01000001_gene2912	1.14e-118	341.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_1255775_3	1178825.ALIH01000010_gene451	1.56e-71	217.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1I2XJ@117743|Flavobacteriia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k59_578693_1	1121918.ARWE01000001_gene350	2.84e-156	454.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,43SU0@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	thiamine pyrophosphate protein TPP binding domain protein	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1085795_1	929558.SMGD1_1538	1.29e-56	184.0	COG4121@1|root,COG4121@2|Bacteria,1Q8T8@1224|Proteobacteria,42RAP@68525|delta/epsilon subdivisions,2YP3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_1085795_2	326298.Suden_1936	7.21e-10	57.4	2BTM2@1|root,32NTT@2|Bacteria,1Q3YE@1224|Proteobacteria,42XZF@68525|delta/epsilon subdivisions,2YQTV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_804675_1	323850.Shew_1595	3.25e-79	240.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,1S3T3@1236|Gammaproteobacteria,2Q93P@267890|Shewanellaceae	1236|Gammaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_240025_1	326298.Suden_1611	1.65e-55	187.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1255783_1	572477.Alvin_0467	8.55e-29	115.0	COG0587@1|root,COG1372@1|root,COG0587@2|Bacteria,COG1372@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
k59_70531_1	1121931.AUHG01000019_gene3022	4.55e-28	104.0	COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1I32P@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_70531_2	143224.JQMD01000002_gene3399	4.81e-17	82.0	COG0417@1|root,COG0417@2|Bacteria,4NGEJ@976|Bacteroidetes,1HXZC@117743|Flavobacteriia	976|Bacteroidetes	L	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_12933_1	411154.GFO_1803	5.66e-39	132.0	COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes,1I40J@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_12933_2	1121931.AUHG01000017_gene1497	9.82e-51	163.0	2CFV0@1|root,32XS2@2|Bacteria,4NUBZ@976|Bacteroidetes,1I4UP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747544_1	1123518.ARWI01000001_gene1260	1.87e-75	233.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,460AH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_747544_2	1123514.KB905899_gene2014	9.02e-29	104.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria	1224|Proteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	ThiS
k59_409085_1	1172190.M947_03785	3.24e-93	286.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2YMJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_1708444_1	1380600.AUYN01000009_gene1655	1.85e-168	485.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1HWXI@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
k59_1537968_1	1121937.AUHJ01000036_gene2809	8.63e-75	236.0	COG2801@1|root,COG2801@2|Bacteria,1R6TH@1224|Proteobacteria,1RRWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
k59_1425352_1	411154.GFO_1769	1.72e-40	150.0	COG4219@1|root,COG4219@2|Bacteria,4NHAY@976|Bacteroidetes,1HXH6@117743|Flavobacteriia	976|Bacteroidetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
k59_1425352_2	1121931.AUHG01000017_gene1531	1.21e-38	143.0	COG4219@1|root,COG4219@2|Bacteria,4NHAY@976|Bacteroidetes,1HXH6@117743|Flavobacteriia	976|Bacteroidetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
k59_1085819_1	1406840.Q763_16435	2.81e-40	145.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1HWUA@117743|Flavobacteriia,2NSZA@237|Flavobacterium	976|Bacteroidetes	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1085819_2	1380600.AUYN01000009_gene1649	3.66e-165	470.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1HX8A@117743|Flavobacteriia	976|Bacteroidetes	S	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
k59_1085819_3	1123037.AUDE01000018_gene2925	8.23e-10	69.7	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
k59_70557_1	572480.Arnit_2873	2.99e-63	218.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_296117_1	391587.KAOT1_15618	8.76e-92	293.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31
k59_296117_2	216432.CA2559_05105	1.08e-118	353.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1HYB7@117743|Flavobacteriia	976|Bacteroidetes	G	alpha amylase, catalytic	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
k59_183687_1	1537917.JU82_09795	6.58e-96	294.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1274085_1	575564.HMPREF0014_00885	1.52e-26	105.0	COG0560@1|root,COG0560@2|Bacteria,1MXGP@1224|Proteobacteria,1RQNV@1236|Gammaproteobacteria,3NJEE@468|Moraxellaceae	1236|Gammaproteobacteria	E	haloacid dehalogenase-like hydrolase	cicA	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_824067_1	945713.IALB_2912	2.39e-85	262.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	MA20_17715	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
k59_201874_1	1121931.AUHG01000012_gene2854	1.11e-56	195.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_596072_1	531844.FIC_00375	1.59e-90	280.0	COG0438@1|root,COG0438@2|Bacteria,4NG90@976|Bacteroidetes,1HZBR@117743|Flavobacteriia,406SZ@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_596072_2	536227.CcarbDRAFT_3650	6.97e-70	221.0	COG3233@1|root,COG3233@2|Bacteria,1UYHF@1239|Firmicutes,25DZY@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
k59_427395_1	159087.Daro_4007	1.32e-06	48.9	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2VN1E@28216|Betaproteobacteria,2KUEP@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_427395_2	76114.ebA3738	2.62e-18	83.6	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,2KV3E@206389|Rhodocyclales	206389|Rhodocyclales	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_765441_1	571166.KI421509_gene1938	6.98e-124	362.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,2TUN8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1784038_1	641526.ADIWIN_0798	3.41e-109	327.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_369922_1	572480.Arnit_0858	2.86e-10	60.1	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YNB0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	periplasmic solute binding protein	znuA	-	-	ko:K02077,ko:K09815	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
k59_369922_2	572480.Arnit_0857	1.8e-51	164.0	COG0735@1|root,COG0735@2|Bacteria,1NCW6@1224|Proteobacteria,42VHY@68525|delta/epsilon subdivisions,2YQK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1443001_1	1121931.AUHG01000010_gene820	4.89e-34	128.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_1443001_2	411154.GFO_0159	2.75e-43	144.0	2C8TJ@1|root,32RMV@2|Bacteria,4NSAA@976|Bacteroidetes,1I54A@117743|Flavobacteriia	976|Bacteroidetes	S	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_878967_1	944547.ABLL_0443	8.56e-165	478.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1332734_1	891974.E05_50800	2.23e-10	60.1	2AD7J@1|root,312WH@2|Bacteria,1RHF8@1224|Proteobacteria,1S7Q4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
k59_1332734_2	367737.Abu_0455	1.07e-44	170.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CHE@68525|delta/epsilon subdivisions,2YRKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_201912_1	945713.IALB_2930	1.79e-68	216.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_878974_1	411154.GFO_1613	2.85e-78	239.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
k59_1048082_1	1121931.AUHG01000015_gene1212	1.57e-14	68.6	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
k59_1208454_1	1380600.AUYN01000003_gene158	7.12e-90	279.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
k59_30339_1	945713.IALB_0638	8.48e-107	319.0	COG0195@1|root,COG0195@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_144210_1	1123228.AUIH01000028_gene440	5.85e-75	235.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria,1XJC3@135619|Oceanospirillales	135619|Oceanospirillales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	GHL13,Polysacc_deac_1
k59_765490_1	411154.GFO_3354	5.72e-122	349.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1HY1G@117743|Flavobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
k59_653662_1	305700.B447_20578	8.73e-37	127.0	2E6EI@1|root,33120@2|Bacteria,1NA6C@1224|Proteobacteria,2VW1M@28216|Betaproteobacteria,2KX0S@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144215_1	458817.Shal_0953	1.46e-173	510.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,2Q9PC@267890|Shewanellaceae	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1386381_1	1123514.KB905902_gene194	1.44e-85	276.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,462AR@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
k59_259016_1	1122951.ATUE01000006_gene1325	6.31e-103	329.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,3NJ8A@468|Moraxellaceae	1236|Gammaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1443071_1	323850.Shew_0497	2.77e-80	255.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,2QB0M@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	dauA_1	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_987202_1	1121931.AUHG01000010_gene114	2.65e-121	353.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1HWNB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_1388650_1	1137281.D778_02022	8.19e-143	423.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1HXWN@117743|Flavobacteriia	976|Bacteroidetes	K	RNA binding protein with S1 RNA-binding domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1445163_1	1353276.JADR01000003_gene2688	1.16e-22	101.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA
k59_1445163_2	688270.Celal_3417	4.21e-32	112.0	2E4WC@1|root,32ZQG@2|Bacteria,4NUNE@976|Bacteroidetes,1I503@117743|Flavobacteriia,1F9N9@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1445163_3	886377.Murru_2985	9.41e-35	130.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
k59_1558012_1	90814.KL370891_gene544	1.25e-47	171.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,45ZPD@72273|Thiotrichales	72273|Thiotrichales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_542181_1	1178825.ALIH01000009_gene1271	2.04e-38	130.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_542181_2	504487.JCM19302_4142	6.13e-99	292.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1HYQ9@117743|Flavobacteriia	976|Bacteroidetes	E	Lysine transporter LysE	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_261096_1	1123514.KB905899_gene1420	3.42e-56	192.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,4604H@72273|Thiotrichales	72273|Thiotrichales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_261096_2	90814.KL370891_gene713	7.04e-185	523.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,460BP@72273|Thiotrichales	72273|Thiotrichales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_261096_3	1123518.ARWI01000001_gene599	3.27e-09	57.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,460QQ@72273|Thiotrichales	72273|Thiotrichales	N	Role in flagellar biosynthesis	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_1786127_1	1122207.MUS1_13230	1.26e-146	423.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XI8P@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_N
k59_1786130_1	1392490.JHZX01000001_gene87	3.51e-27	108.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_1786130_2	983544.Lacal_2565	4.68e-85	259.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_598074_1	1178825.ALIH01000002_gene937	3.35e-129	379.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1209826_1	269799.Gmet_0880	3.89e-74	239.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,43UE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	FP	metal-dependent phosphohydrolase, HD sub domain	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
k59_146426_1	1121931.AUHG01000011_gene2341	2.03e-98	295.0	COG0399@1|root,COG0399@2|Bacteria,4NGI4@976|Bacteroidetes,1HYZI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_1617465_1	929558.SMGD1_2306	1.04e-202	566.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2YMAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_542215_1	509635.N824_01330	9.04e-33	130.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IPF5@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_656007_1	1484460.JSWG01000008_gene1920	3.37e-139	413.0	COG0642@1|root,COG3290@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_656007_2	1392490.JHZX01000001_gene328	1.32e-09	58.2	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
k59_317011_1	1380600.AUYN01000011_gene947	2.52e-50	181.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1106277_1	90814.KL370891_gene1443	2.54e-91	283.0	COG4564@1|root,COG4564@2|Bacteria,1QVX9@1224|Proteobacteria	1224|Proteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	dCache_2
k59_1503733_1	1380600.AUYN01000009_gene1147	4.95e-76	236.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
k59_1729019_1	504487.JCM19302_3046	7.81e-60	186.0	COG0526@1|root,COG0526@2|Bacteria,4NQ6I@976|Bacteroidetes,1I2YE@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	trxA_1	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_1729019_2	745718.JADT01000001_gene1599	6.55e-47	151.0	2CIDP@1|root,32S8D@2|Bacteria,4NS8C@976|Bacteroidetes,1I42Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1729019_3	675813.VIB_002483	2.16e-41	150.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1XSIF@135623|Vibrionales	135623|Vibrionales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_936276_1	945021.TEH_17520	2.79e-28	114.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,4AZEG@81852|Enterococcaceae	91061|Bacilli	K	Protein of unknown function (DUF_B2219)	yvoA_2	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k59_989492_1	929558.SMGD1_2766	7.29e-118	351.0	COG2984@1|root,COG2984@2|Bacteria,1PGQI@1224|Proteobacteria,43496@68525|delta/epsilon subdivisions,2YRIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_714811_1	929558.SMGD1_0778	2.47e-62	198.0	COG0457@1|root,COG0457@2|Bacteria,1NRB9@1224|Proteobacteria,42W0K@68525|delta/epsilon subdivisions,2YQ9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
k59_714811_2	563040.Saut_1764	1.19e-136	390.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,42MHJ@68525|delta/epsilon subdivisions,2YMM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	dinuclear metal center protein, YbgI	-	-	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
k59_261171_1	643867.Ftrac_1608	2.3e-32	129.0	COG0642@1|root,COG0834@1|root,COG0834@2|Bacteria,COG2205@2|Bacteria,4NK0U@976|Bacteroidetes,47YDI@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,SBP_bac_3
k59_429777_1	1121904.ARBP01000014_gene105	1.57e-23	103.0	COG3119@1|root,COG3386@1|root,COG3119@2|Bacteria,COG3386@2|Bacteria,4NETT@976|Bacteroidetes	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	SGL,Sulfatase
k59_1276471_1	497321.C664_17997	6.83e-89	266.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,2KUYM@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_146489_1	1237149.C900_03964	8.57e-61	206.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_881350_1	991.IW20_21100	3.95e-20	91.7	2D1GA@1|root,32TAN@2|Bacteria,4NSH6@976|Bacteroidetes,1I2BP@117743|Flavobacteriia,2NT66@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1672716_1	1123228.AUIH01000035_gene2839	1.01e-39	150.0	COG4264@1|root,COG4264@2|Bacteria,1NEZU@1224|Proteobacteria,1RN4A@1236|Gammaproteobacteria,1XQSH@135619|Oceanospirillales	135619|Oceanospirillales	Q	IucA / IucC family	-	-	-	-	-	-	-	-	-	-	-	-	FhuF,IucA_IucC
k59_372192_1	1121931.AUHG01000010_gene196	1.83e-31	118.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1HYJS@117743|Flavobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_372192_2	411154.GFO_3213	2.8e-61	196.0	COG0266@1|root,COG0266@2|Bacteria,4NFM2@976|Bacteroidetes,1HYNY@117743|Flavobacteriia	976|Bacteroidetes	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_1729062_1	985255.APHJ01000021_gene1703	5.52e-101	296.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia,2P60E@244698|Gillisia	976|Bacteroidetes	P	Carbonic anhydrase	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_204258_1	411154.GFO_0622	1.93e-119	353.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_486688_1	555500.I215_11584	9.09e-198	565.0	COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,1HZJZ@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_1335177_1	156889.Mmc1_2685	2.97e-79	267.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
k59_1106344_1	1177928.TH2_04158	2.26e-52	174.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2U4E5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
k59_881367_1	1380600.AUYN01000003_gene113	7.89e-103	310.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1HXAF@117743|Flavobacteriia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1729073_2	1380600.AUYN01000006_gene649	0.0	948.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1HXFR@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_1729073_3	1197477.IA57_06315	5.83e-10	60.1	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_204278_2	1178825.ALIH01000002_gene877	4.39e-42	142.0	COG0346@1|root,COG0346@2|Bacteria,4NMSQ@976|Bacteroidetes,1I1P9@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_146540_2	411154.GFO_2860	2.71e-92	274.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1HXJ3@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_261252_1	1178825.ALIH01000007_gene1684	1.13e-139	398.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1HYH7@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1558176_1	317025.Tcr_2038	3.92e-113	349.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,462CC@72273|Thiotrichales	72273|Thiotrichales	C	Hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_826630_1	929558.SMGD1_0310	1.99e-111	332.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1276538_1	717774.Marme_2883	2.23e-94	281.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1S18F@1236|Gammaproteobacteria,1XNX4@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate	-	-	4.1.1.3	ko:K01003	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
k59_1729118_1	225849.swp_0141	1.13e-11	62.8	2CX2C@1|root,32T0Z@2|Bacteria,1N40Z@1224|Proteobacteria,1SA1U@1236|Gammaproteobacteria,2QBGX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3157
k59_1729118_2	323850.Shew_3755	2.56e-62	194.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,1SCN1@1236|Gammaproteobacteria,2QC1Y@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1276549_1	1121912.AUHD01000001_gene2384	6.51e-64	207.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1HYZG@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1276549_2	1347342.BN863_4200	7.47e-16	76.3	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1HXDR@117743|Flavobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_598195_1	985255.APHJ01000026_gene2250	2.51e-67	213.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia,2P6B3@244698|Gillisia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_146574_1	1124780.ANNU01000010_gene3639	1.66e-39	145.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
k59_146574_2	356851.JOAN01000015_gene2680	6.68e-09	58.5	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4DDT0@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_1014240_1	563040.Saut_1406	3.94e-49	166.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,42W4N@68525|delta/epsilon subdivisions	1224|Proteobacteria	D	Sporulation related domain	ftsN	-	-	ko:K03591,ko:K03749	-	-	-	-	ko00000,ko03036	-	-	-	SPOR
k59_1072460_1	1191523.MROS_0772	2.36e-72	234.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
k59_620853_1	296591.Bpro_4594	6.28e-114	339.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VJ1V@28216|Betaproteobacteria,4AAER@80864|Comamonadaceae	28216|Betaproteobacteria	C	Nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11,Nitr_red_bet_C
k59_54595_1	879212.DespoDRAFT_00973	6.78e-21	94.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_566116_2	1178825.ALIH01000004_gene2843	3.65e-34	117.0	2E59P@1|root,3301Z@2|Bacteria,4NUUS@976|Bacteroidetes,1I52U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1400_1	1232410.KI421418_gene2274	1.85e-102	298.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,43TG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_1187551_1	504487.JCM19302_3407	1.14e-46	170.0	COG0823@1|root,COG1523@1|root,COG0823@2|Bacteria,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_340010_1	1122201.AUAZ01000009_gene2768	1.8e-64	204.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,46461@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1177 ABC-type spermidine putrescine transport system, permease component II	potI	-	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
k59_848209_1	1178825.ALIH01000005_gene248	7.05e-42	148.0	COG0415@1|root,COG0415@2|Bacteria,4NDW0@976|Bacteroidetes,1HWUN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phrB3	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_848209_2	1178825.ALIH01000005_gene249	1.13e-66	218.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to deoxyribodipyrimidine photolyase	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_1131132_1	391603.FBALC1_11107	1.48e-99	292.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1I1AG@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
k59_1131132_2	1469557.JSWF01000019_gene229	3.74e-75	226.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I20A@117743|Flavobacteriia	976|Bacteroidetes	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_1018135_1	411154.GFO_3189	4.72e-202	569.0	COG1488@1|root,COG1488@2|Bacteria,4NFQK@976|Bacteroidetes,1HYY6@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k59_1243675_1	411154.GFO_3248	1.55e-59	188.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1243675_2	688270.Celal_1518	1.1e-10	62.4	2E32X@1|root,32Y35@2|Bacteria,4NUUU@976|Bacteroidetes,1I54Q@117743|Flavobacteriia,1F9HH@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57908_1	945713.IALB_1065	9.27e-104	323.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_961557_1	411154.GFO_0071	2.15e-66	211.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_961557_2	1250278.JQNQ01000001_gene1147	2.63e-24	99.8	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1526381_2	572480.Arnit_2955	2.03e-93	281.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2YN4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_679264_1	362418.IW19_03220	7.29e-09	60.5	2EEXA@1|root,338QN@2|Bacteria,4NWR3@976|Bacteroidetes,1IC12@117743|Flavobacteriia,2NXND@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1639521_1	1051646.VITU9109_25745	6.23e-41	151.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,1RN69@1236|Gammaproteobacteria,1XWMY@135623|Vibrionales	135623|Vibrionales	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k59_1300595_1	1121912.AUHD01000006_gene1325	8.21e-68	218.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1300595_2	985255.APHJ01000021_gene1293	2.51e-16	75.9	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,2P6F8@244698|Gillisia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_509322_1	572480.Arnit_1713	5.85e-148	431.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_227357_1	1121931.AUHG01000010_gene253	6.08e-143	410.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1356766_1	1380600.AUYN01000009_gene1155	2.32e-201	580.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_679276_1	1232410.KI421422_gene2030	3.85e-63	204.0	COG0457@1|root,COG0457@2|Bacteria,1N3FU@1224|Proteobacteria,42UWS@68525|delta/epsilon subdivisions,2WR2J@28221|Deltaproteobacteria,43SMZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
k59_1526393_1	929558.SMGD1_0604	9.22e-166	491.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_227360_1	1123518.ARWI01000001_gene2172	4.01e-77	236.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_227360_2	1123518.ARWI01000001_gene2173	2.59e-52	176.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_340053_1	317025.Tcr_0854	4.29e-96	302.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_566195_1	1123518.ARWI01000001_gene1463	4.06e-159	468.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_566195_2	1165841.SULAR_03522	9.77e-56	178.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1243707_1	1484460.JSWG01000006_gene2931	1.41e-92	290.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1I0HE@117743|Flavobacteriia	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1243707_2	1484460.JSWG01000006_gene2932	1.34e-46	153.0	2DPVF@1|root,333JB@2|Bacteria,4NX32@976|Bacteroidetes,1I5NQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1243708_1	1249997.JHZW01000003_gene2129	2.13e-72	223.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1HXQK@117743|Flavobacteriia,2PGXJ@252356|Maribacter	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
k59_1243708_2	1121931.AUHG01000012_gene2532	8.28e-30	111.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1HY0K@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1018198_1	1442598.JABW01000028_gene1015	1.53e-134	399.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2YMUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1526421_1	234831.PSM_B0522	1.32e-39	153.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q0WZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,DUF4118,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_1356789_1	1380600.AUYN01000012_gene2949	1.9e-11	63.9	COG1011@1|root,COG1011@2|Bacteria,4NQJ0@976|Bacteroidetes,1I1I6@117743|Flavobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k59_1356789_2	1392489.JPOL01000002_gene3119	1.01e-56	186.0	COG0189@1|root,COG0189@2|Bacteria,4NHX0@976|Bacteroidetes,1IJ8Z@117743|Flavobacteriia	976|Bacteroidetes	HJ	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
k59_905237_1	1123517.JOMR01000001_gene903	4.05e-48	162.0	COG2199@1|root,COG2199@2|Bacteria,1R4XN@1224|Proteobacteria,1RQ6S@1236|Gammaproteobacteria,461US@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
k59_905237_2	1123518.ARWI01000001_gene2419	8.87e-180	513.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_227390_1	1249480.B649_05385	2.2e-05	45.8	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_227390_2	1172190.M947_10240	2.12e-63	204.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_792146_1	517418.Ctha_0342	1.75e-23	104.0	COG0737@1|root,COG3391@1|root,COG0737@2|Bacteria,COG3391@2|Bacteria,1FDAF@1090|Chlorobi	1090|Chlorobi	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,SWM_repeat
k59_1582994_1	1469557.JSWF01000032_gene3215	9.14e-45	156.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_1582994_2	1250006.JHZZ01000001_gene838	1.56e-51	164.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,1I1Z0@117743|Flavobacteriia,3VWI7@52959|Polaribacter	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
k59_1582994_3	1380600.AUYN01000009_gene1237	0.0	912.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1HYKS@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
k59_1582994_4	1380600.AUYN01000009_gene1236	0.0	892.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1HWP9@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
k59_679334_1	317025.Tcr_0173	6.07e-79	246.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,461Q2@72273|Thiotrichales	72273|Thiotrichales	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_961636_1	886377.Murru_0760	0.0	1444.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1131240_1	94122.Shewana3_4019	4.74e-46	166.0	COG0840@1|root,COG0840@2|Bacteria,1QCVC@1224|Proteobacteria,1RX4H@1236|Gammaproteobacteria,2QADI@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_848312_2	1380600.AUYN01000006_gene505	2.98e-68	206.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1I2SS@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_848312_3	1121912.AUHD01000002_gene3181	4.4e-113	326.0	COG0740@1|root,COG0740@2|Bacteria,4NF77@976|Bacteroidetes,1HXAR@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_848312_4	886377.Murru_2337	6.57e-107	337.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
k59_58029_1	1121352.JHZP01000001_gene578	0.00083	40.8	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,2KQ0X@206351|Neisseriales	206351|Neisseriales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_58029_2	323850.Shew_3143	3.41e-68	211.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,2Q9KI@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_283809_1	572480.Arnit_2578	4.46e-99	300.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1413695_1	1122176.KB903531_gene3155	1.74e-67	218.0	COG0624@1|root,COG0624@2|Bacteria,4NJBF@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_1752565_1	1121430.JMLG01000018_gene250	1.6e-56	192.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,260ZD@186807|Peptococcaceae	186801|Clostridia	C	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1187722_1	531844.FIC_00375	1.14e-30	117.0	COG0438@1|root,COG0438@2|Bacteria,4NG90@976|Bacteroidetes,1HZBR@117743|Flavobacteriia,406SZ@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1187722_2	1380600.AUYN01000001_gene2282	4.14e-169	477.0	COG0463@1|root,COG0463@2|Bacteria,4NGTD@976|Bacteroidetes,1I0ZD@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1187722_3	1443665.JACA01000005_gene400	4.28e-65	208.0	28IAS@1|root,2Z8DC@2|Bacteria,4NFA2@976|Bacteroidetes,1HYWQ@117743|Flavobacteriia,2YJ2M@290174|Aquimarina	976|Bacteroidetes	S	EpsG family	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
k59_1131289_1	1122225.AULQ01000007_gene2320	5.56e-188	532.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_735810_1	1123518.ARWI01000001_gene1682	3.28e-65	228.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,4629D@72273|Thiotrichales	72273|Thiotrichales	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k59_735810_2	1123514.KB905900_gene2104	2.62e-41	146.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,45ZWG@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,HemN_C,Radical_SAM
k59_905339_1	1123518.ARWI01000001_gene1410	3.08e-159	466.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,45ZQH@72273|Thiotrichales	72273|Thiotrichales	E	peptidase	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1639682_1	1123514.KB905899_gene1537	4.84e-75	244.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_622913_1	326298.Suden_1213	1.68e-103	313.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42QN4@68525|delta/epsilon subdivisions,2YTQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1637_1	1168067.JAGP01000001_gene198	5.43e-15	70.5	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4615J@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_1637_2	1123518.ARWI01000001_gene1119	3.87e-161	460.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	recE	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008309,GO:0008409,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0035312,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051908,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	2.7.7.7,3.6.4.12	ko:K02335,ko:K02342,ko:K03654,ko:K03722,ko:K10906	ko00230,ko00240,ko01100,ko03018,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03410,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,Helicase_C,RNase_T,UvrD-helicase,UvrD_C
k59_283873_1	1123228.AUIH01000008_gene2440	3.16e-36	136.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1XJZA@135619|Oceanospirillales	135619|Oceanospirillales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_792272_1	929558.SMGD1_2449	1.08e-114	352.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1PGYK@1224|Proteobacteria,42YPW@68525|delta/epsilon subdivisions,2YR2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_114575_1	867900.Celly_0996	6e-46	162.0	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1356897_1	411154.GFO_2345	8.12e-45	161.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXPB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_1356897_2	1250278.JQNQ01000001_gene1034	2.33e-10	57.4	COG4270@1|root,COG4270@2|Bacteria,4NQAY@976|Bacteroidetes,1I2U0@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG4270 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
k59_735859_1	1123326.JFBL01000009_gene875	4.51e-102	311.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,42N88@68525|delta/epsilon subdivisions,2YNQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	L-serine deaminase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_471004_2	411154.GFO_3098	8.17e-16	71.6	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_526741_1	90814.KL370891_gene660	5.84e-13	67.8	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,460ER@72273|Thiotrichales	72273|Thiotrichales	T	Chemotaxis protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_526741_2	1123514.KB905899_gene1468	4.53e-171	493.0	COG1462@1|root,COG1462@2|Bacteria,1RIEQ@1224|Proteobacteria,1RURU@1236|Gammaproteobacteria,462A7@72273|Thiotrichales	72273|Thiotrichales	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_526741_3	1168067.JAGP01000001_gene1350	2.93e-56	178.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,46101@72273|Thiotrichales	72273|Thiotrichales	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k59_526741_4	1123514.KB905899_gene1466	7.5e-79	236.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,460W1@72273|Thiotrichales	72273|Thiotrichales	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_526741_5	1123514.KB905899_gene1465	4.28e-30	112.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,4617F@72273|Thiotrichales	72273|Thiotrichales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
k59_1147142_1	90814.KL370891_gene1763	2.51e-164	474.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,45ZT2@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1035135_1	317025.Tcr_1118	4.55e-109	329.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,45ZPK@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_413978_1	1123514.KB905899_gene1111	1.96e-88	273.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,45ZPB@72273|Thiotrichales	72273|Thiotrichales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_1770160_1	1172190.M947_04430	1.74e-68	213.0	COG0745@1|root,COG0745@2|Bacteria,1PFKD@1224|Proteobacteria,42TIQ@68525|delta/epsilon subdivisions,2YPWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_921622_1	504487.JCM19302_4151	5.58e-11	60.8	COG5309@1|root,COG5309@2|Bacteria,4NFD7@976|Bacteroidetes,1HY34@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_921622_2	1250005.PHEL85_0893	9.91e-195	556.0	COG1472@1|root,COG1472@2|Bacteria,4NJGK@976|Bacteroidetes,1HZ5M@117743|Flavobacteriia,3VVTB@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
k59_921623_1	439235.Dalk_2022	4.78e-54	184.0	COG4799@1|root,COG4799@2|Bacteria,1MZ7G@1224|Proteobacteria,42Z8S@68525|delta/epsilon subdivisions,2WUDU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
k59_1147153_1	572480.Arnit_0834	4.64e-133	384.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42M7C@68525|delta/epsilon subdivisions,2YTS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1600942_1	572480.Arnit_0388	6.35e-103	323.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,TarH,dCache_2,sCache_2
k59_640266_1	1178825.ALIH01000005_gene284	3.86e-132	377.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_245139_1	90814.KL370891_gene1851	2.81e-19	84.7	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_245139_2	1123514.KB905903_gene381	3.25e-55	180.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,4602G@72273|Thiotrichales	72273|Thiotrichales	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_131052_1	1123228.AUIH01000022_gene3124	1.56e-133	423.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHMP@135619|Oceanospirillales	135619|Oceanospirillales	T	Chemotaxis protein histidine kinase and related	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1430143_1	1249480.B649_04350	5.32e-12	66.2	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_1260826_1	497965.Cyan7822_5247	1.85e-36	142.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGDE@43988|Cyanothece	1117|Cyanobacteria	T	PAS fold-4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1199627_2	1123248.KB893316_gene4569	4.82e-21	90.5	COG1082@1|root,COG1082@2|Bacteria,4NFEA@976|Bacteroidetes,1IURN@117747|Sphingobacteriia	976|Bacteroidetes	G	Pfam Xylose	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1199627_3	1235803.C825_03090	2.41e-132	427.0	COG0383@1|root,COG0383@2|Bacteria,4P1Z7@976|Bacteroidetes,2FTJ7@200643|Bacteroidia	976|Bacteroidetes	G	alpha-mannosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_38,Glyco_hydro_38C
k59_809855_1	929558.SMGD1_0786	7.26e-48	161.0	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_809855_2	929558.SMGD1_0787	8.01e-66	204.0	2AMMX@1|root,31CI0@2|Bacteria,1Q8WA@1224|Proteobacteria,42UGB@68525|delta/epsilon subdivisions,2YPW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_697530_1	990073.ATHU01000001_gene1798	1.26e-27	103.0	COG0633@1|root,COG0633@2|Bacteria,1PSR6@1224|Proteobacteria,42XGK@68525|delta/epsilon subdivisions,2YQWI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_697530_2	1537917.JU82_01565	1.75e-56	176.0	COG0633@1|root,COG0633@2|Bacteria,1NJF0@1224|Proteobacteria,42U1V@68525|delta/epsilon subdivisions,2YQ25@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_697530_3	1537917.JU82_01570	1.95e-18	83.6	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YNGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1430193_1	929558.SMGD1_2300	8.54e-103	308.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1657067_1	926559.JoomaDRAFT_1570	5.33e-28	109.0	COG3464@1|root,COG3464@2|Bacteria,4NFK7@976|Bacteroidetes,1HX8S@117743|Flavobacteriia	976|Bacteroidetes	L	COG3464 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k59_1318768_1	1380600.AUYN01000006_gene306	4.7e-87	270.0	COG1577@1|root,COG2827@1|root,COG1577@2|Bacteria,COG2827@2|Bacteria,4NEXC@976|Bacteroidetes,1HY6C@117743|Flavobacteriia	976|Bacteroidetes	I	GHMP Kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1318768_2	1380600.AUYN01000006_gene313	2.39e-49	173.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_809886_1	980584.AFPB01000168_gene1926	3.02e-34	127.0	COG2126@1|root,COG2126@2|Bacteria,4PPD0@976|Bacteroidetes,1IKIM@117743|Flavobacteriia	976|Bacteroidetes	J	Ion transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans
k59_1090663_1	572480.Arnit_2343	1.75e-99	295.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2YMRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_752328_1	1168067.JAGP01000001_gene290	1.01e-69	237.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,1SYT2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Autotransporter beta-domain	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	Autotransporter,PAP2,PATR
k59_583464_1	572480.Arnit_1768	3.48e-147	416.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42THA@68525|delta/epsilon subdivisions,2YPB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_865758_1	411154.GFO_3347	4.09e-96	283.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1HXMN@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_865758_2	1121931.AUHG01000010_gene337	9.93e-39	138.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1770273_1	1123518.ARWI01000001_gene848	2.99e-22	94.4	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1770273_2	1123518.ARWI01000001_gene850	1.03e-38	139.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,460RX@72273|Thiotrichales	72273|Thiotrichales	L	ATP dependent DNA ligase domain	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_356705_2	1380600.AUYN01000003_gene203	5.63e-105	311.0	28Z2A@1|root,2ZKUT@2|Bacteria,4NSQ0@976|Bacteroidetes,1I0GS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_356705_3	1380600.AUYN01000003_gene202	1.43e-59	189.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1I2EY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_356705_4	1042376.AFPK01000071_gene712	0.000119	44.7	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia,405VS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_640360_1	90814.KL370891_gene910	2.41e-93	283.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,460BD@72273|Thiotrichales	72273|Thiotrichales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_640360_2	1123514.KB905899_gene728	2.03e-113	337.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine	dcyD	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
k59_640360_3	90814.KL370891_gene908	4.99e-185	520.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,1RSA6@1236|Gammaproteobacteria,45ZTC@72273|Thiotrichales	72273|Thiotrichales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1260891_1	83406.HDN1F_12400	2.42e-21	101.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_3,PAS_4
k59_975604_1	1123228.AUIH01000026_gene3918	9.7e-82	258.0	COG4191@1|root,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,1T23G@1236|Gammaproteobacteria,1XS1R@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_301267_1	411154.GFO_2863	8.36e-209	630.0	COG4932@1|root,COG4935@1|root,COG4932@2|Bacteria,COG4935@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_1487546_1	367737.Abu_0455	2.63e-15	78.2	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CHE@68525|delta/epsilon subdivisions,2YRKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_471172_1	946077.W5A_03044	5.88e-33	122.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia	976|Bacteroidetes	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_1430245_1	1137281.D778_00658	3.09e-72	217.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
k59_1430245_2	1380600.AUYN01000009_gene1498	1.31e-65	216.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
k59_697605_1	998088.B565_3072	2.98e-32	119.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales	135624|Aeromonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_697605_2	466038.KI421440_gene1432	1.98e-30	115.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,4BPV9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
k59_526907_1	1122179.KB890469_gene596	2.17e-61	216.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,Reg_prop,Response_reg,Y_Y_Y
k59_1090719_3	1178825.ALIH01000001_gene2613	1.08e-73	222.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1I1ZW@117743|Flavobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_1199703_1	90814.KL370891_gene1624	9.8e-110	327.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,4607Z@72273|Thiotrichales	72273|Thiotrichales	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1373383_1	1123228.AUIH01000024_gene3222	6.91e-100	311.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XH7Q@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_245313_1	929713.NIASO_18295	2.31e-55	184.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1IQQH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_583541_1	411154.GFO_2674	4.48e-09	56.6	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1HYYA@117743|Flavobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_583541_3	1250232.JQNJ01000001_gene2524	1.97e-23	100.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_131197_1	1121912.AUHD01000004_gene2148	1.62e-29	117.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1HXPG@117743|Flavobacteriia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_131197_2	1380600.AUYN01000001_gene2354	7.09e-24	98.6	2CDHR@1|root,341P0@2|Bacteria,4P49J@976|Bacteroidetes,1I9WB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_975658_1	675806.VII_001013	9.14e-19	92.8	COG0642@1|root,COG0784@1|root,COG4192@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4192@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Y35E@135623|Vibrionales	135623|Vibrionales	T	Histidine Phosphotransfer domain	torS	-	2.7.13.3	ko:K07647	ko02020,map02020	M00455	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,Response_reg
k59_1318868_1	572480.Arnit_1711	6.01e-193	546.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2YN1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_640440_1	458817.Shal_1143	1.67e-68	207.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,2QBVX@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_640440_2	326297.Sama_0934	2.3e-40	138.0	COG4970@1|root,COG4970@2|Bacteria,1Q92Y@1224|Proteobacteria,1SX5X@1236|Gammaproteobacteria,2QBV8@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k59_1260980_1	1565129.JSFF01000001_gene1130	2.37e-118	357.0	COG3303@1|root,COG3303@2|Bacteria,1QXF8@1224|Proteobacteria,1T3AB@1236|Gammaproteobacteria,2QEU6@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_810002_1	1123518.ARWI01000001_gene1858	9.32e-22	94.4	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,460M9@72273|Thiotrichales	72273|Thiotrichales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_810002_2	1123518.ARWI01000001_gene1859	2.91e-97	312.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,4614F@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_9
k59_1199724_1	1380600.AUYN01000009_gene1580	1.13e-167	483.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1HXQU@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_131202_1	1123518.ARWI01000001_gene2095	3.02e-88	268.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,4604R@72273|Thiotrichales	72273|Thiotrichales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_131202_2	497964.CfE428DRAFT_2938	1.71e-17	86.7	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_526953_1	326298.Suden_0283	1.02e-102	313.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42PPM@68525|delta/epsilon subdivisions,2YN9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	tlpD	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1487619_1	1380600.AUYN01000009_gene1733	1.12e-204	590.0	COG4206@1|root,COG4206@2|Bacteria,4PM79@976|Bacteroidetes,1IJK7@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1092417_2	1121931.AUHG01000010_gene489	1.47e-81	244.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
k59_1602927_1	857087.Metme_2136	3.42e-82	272.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XG52@135618|Methylococcales	135618|Methylococcales	T	Metal-dependent phosphohydrolase, HD region, subdomain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
k59_1602927_2	317025.Tcr_0025	1.44e-14	71.2	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,462SK@72273|Thiotrichales	72273|Thiotrichales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_1320625_1	391587.KAOT1_04080	9.88e-72	234.0	2CGU2@1|root,2Z7ZH@2|Bacteria,4NHFA@976|Bacteroidetes,1HWU4@117743|Flavobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_190482_1	1123518.ARWI01000001_gene666	3.85e-75	239.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,46060@72273|Thiotrichales	72273|Thiotrichales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_358414_1	563040.Saut_1823	3.75e-92	287.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_358414_2	929558.SMGD1_1692	6.51e-53	167.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YPSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iIT341.HP1270	Oxidored_q2
k59_976962_2	983544.Lacal_0384	2.49e-12	63.2	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia	976|Bacteroidetes	J	ribosomal protein l17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_699396_1	1121931.AUHG01000001_gene3109	1.61e-123	369.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_754000_2	1565129.JSFF01000001_gene1213	3.48e-23	97.4	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,2QAE5@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1148870_1	929558.SMGD1_2198	3.6e-16	75.5	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2YNV5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_829774_1	1301098.PKB_2585	1.64e-20	89.0	COG1335@1|root,COG1335@2|Bacteria,1REQ3@1224|Proteobacteria,1S45D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k59_1675940_1	387093.SUN_1426	1.74e-121	377.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1109667_1	572480.Arnit_2468	1.94e-05	45.4	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42N1V@68525|delta/epsilon subdivisions,2YRFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22,2.6.1.76	ko:K00836,ko:K07250	ko00250,ko00260,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,ko01210,ko01230,map00250,map00260,map00280,map00410,map00640,map00650,map01100,map01120,map01210,map01230	M00027,M00033	R00908,R01648,R04188,R06977	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1109667_2	572480.Arnit_2469	2.8e-81	244.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,42V5R@68525|delta/epsilon subdivisions,2YSS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Acetyltransferase (GNAT) family	-	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_938907_1	1443665.JACA01000034_gene2471	9.6e-102	317.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2YGJR@290174|Aquimarina	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
k59_1732328_1	62928.azo3651	4.55e-83	267.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	mcrA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_992718_1	1380600.AUYN01000006_gene650	4.08e-74	236.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1HY2X@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_992718_2	745718.JADT01000020_gene276	5.51e-106	312.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1HWPD@117743|Flavobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
k59_1212505_1	1236542.BALM01000014_gene1155	5.08e-62	209.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1279820_1	1094466.KQS_10485	1.65e-102	308.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1I0C6@117743|Flavobacteriia,2NSY9@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
k59_1279820_2	1453498.LG45_07830	6.81e-73	234.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1HYER@117743|Flavobacteriia,2NT9Q@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_544843_1	1237149.C900_00894	9.29e-109	332.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
k59_433154_1	1380600.AUYN01000003_gene209	4.2e-229	640.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1HWJU@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_433154_2	1443665.JACA01000058_gene1072	3.78e-38	132.0	COG0666@1|root,COG0666@2|Bacteria,4NSDC@976|Bacteroidetes,1I46H@117743|Flavobacteriia,2YJT0@290174|Aquimarina	976|Bacteroidetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
k59_1052768_1	1298593.TOL_0843	3.45e-58	191.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XHFQ@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_1109734_1	90813.JQMT01000001_gene675	6.65e-34	134.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,46172@72273|Thiotrichales	72273|Thiotrichales	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_1620661_1	886377.Murru_3274	3.64e-72	232.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,1HWVE@117743|Flavobacteriia	976|Bacteroidetes	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_207587_1	326298.Suden_0006	3.81e-234	656.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_544870_1	1305737.JAFX01000001_gene727	1.46e-21	93.6	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,47VP9@768503|Cytophagia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_544870_2	489825.LYNGBM3L_23830	3.48e-15	75.9	COG2335@1|root,COG2335@2|Bacteria,1G6R4@1117|Cyanobacteria,1HBIV@1150|Oscillatoriales	1117|Cyanobacteria	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_1279877_1	1172190.M947_00600	4.96e-15	71.2	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2YPEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_1279877_2	563040.Saut_1147	4.52e-57	183.0	2A2WP@1|root,30RAU@2|Bacteria,1PMAH@1224|Proteobacteria,42Y3T@68525|delta/epsilon subdivisions,2YQRJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LptC
k59_320495_1	880071.Fleli_0960	1.73e-76	239.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KX2@768503|Cytophagia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_829905_1	1565129.JSFF01000026_gene1277	1.61e-10	60.5	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,2Q9YD@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_829905_2	323850.Shew_0203	3.61e-72	223.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,2QB0J@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.7.2.8	ko:K00930,ko:K22478	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255	AA_kinase,NAT
k59_1448650_1	572480.Arnit_1202	4.83e-146	436.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43E1J@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,SBP_bac_3,dCache_2,dCache_3
k59_718280_1	572480.Arnit_2899	3.49e-113	342.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_207625_1	317025.Tcr_0123	2.48e-72	226.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,45ZXW@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_207625_2	90814.KL370892_gene1940	3.65e-190	539.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,460MD@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_207625_3	90814.KL370892_gene1941	2.7e-50	160.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,4616M@72273|Thiotrichales	72273|Thiotrichales	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
k59_207625_4	1123514.KB905900_gene2100	1.41e-76	241.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,460AU@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM A G-specific adenine glycosylase	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_489939_1	317025.Tcr_1779	1.15e-65	213.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,460F3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
k59_489939_2	317025.Tcr_1778	1.02e-30	120.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,45ZY9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_94731_1	392500.Swoo_4769	3.6e-68	217.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,2Q8XF@267890|Shewanellaceae	1236|Gammaproteobacteria	H	MoeA domain protein domain I and II	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_771036_1	709032.Sulku_0052	2.31e-111	333.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_320532_1	411154.GFO_2836	2.7e-94	280.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1HXDV@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_659546_5	1270196.JCKI01000008_gene1532	2.55e-28	112.0	COG3926@1|root,COG3926@2|Bacteria,4NRDK@976|Bacteroidetes	976|Bacteroidetes	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
k59_1620714_1	929558.SMGD1_2727	1.35e-107	311.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2YP0H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_489953_1	351348.Maqu_1721	8.46e-121	356.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,46BCB@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_489953_2	658187.LDG_7064	1.03e-68	219.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_544926_1	391603.FBALC1_02752	1.54e-145	420.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1HYDV@117743|Flavobacteriia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_659567_1	1250278.JQNQ01000001_gene972	2.07e-88	267.0	COG3595@1|root,COG3595@2|Bacteria,4PMD5@976|Bacteroidetes,1IK6I@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k59_1789641_1	326298.Suden_1999	3.81e-20	86.7	2A50M@1|root,30TNT@2|Bacteria,1PDM4@1224|Proteobacteria,42QJ6@68525|delta/epsilon subdivisions,2YPYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMIN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
k59_1789641_3	387093.SUN_1502	2.93e-38	138.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1N68I@1224|Proteobacteria,43BAI@68525|delta/epsilon subdivisions,2YT7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_433285_1	929558.SMGD1_1228	1.96e-36	127.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2YMVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928	GTP_cyclohydroI
k59_320568_1	929558.SMGD1_1545	6.48e-100	292.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2YNX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_1561614_1	1121935.AQXX01000082_gene171	2.32e-74	238.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1XH9M@135619|Oceanospirillales	135619|Oceanospirillales	C	Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k59_544947_1	1123518.ARWI01000001_gene280	1.11e-60	212.0	COG2199@1|root,COG5000@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,1R7HC@1224|Proteobacteria,1T3X6@1236|Gammaproteobacteria,462E3@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_207698_1	929558.SMGD1_1060	3.81e-88	270.0	COG0475@1|root,COG0475@2|Bacteria,1N2RV@1224|Proteobacteria,43B2N@68525|delta/epsilon subdivisions,2YT5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_207698_2	929558.SMGD1_1061	2.96e-50	162.0	COG2078@1|root,COG2078@2|Bacteria,1Q5PY@1224|Proteobacteria,431KR@68525|delta/epsilon subdivisions,2YSE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_207698_3	929558.SMGD1_1062	2.8e-23	95.9	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_1392256_1	572480.Arnit_2604	3.49e-138	415.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,42PYN@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124	Transketolase_N
k59_1451284_1	298386.PBPRA2188	5.02e-73	226.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XTEU@135623|Vibrionales	135623|Vibrionales	E	COG1126 ABC-type polar amino acid transport system, ATPase component	aapP	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_832342_1	760154.Sulba_1005	7.17e-109	344.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02030,ko:K07679	ko02020,ko05133,map02020,map05133	M00236,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
k59_152478_1	1123514.KB905899_gene1716	2.76e-102	303.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,4613U@72273|Thiotrichales	72273|Thiotrichales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_152478_2	1123518.ARWI01000001_gene931	7.96e-96	286.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	motA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_266259_1	1123518.ARWI01000001_gene2228	3.78e-49	165.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1RRM3@1236|Gammaproteobacteria,461HM@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K11707	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_266259_2	1123518.ARWI01000001_gene2227	1.07e-134	385.0	COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,1RS5Y@1236|Gammaproteobacteria,4613H@72273|Thiotrichales	72273|Thiotrichales	P	ABC transporter	-	-	-	ko:K11710	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
k59_1169199_1	929558.SMGD1_1499	5.16e-100	306.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_1282479_1	941824.TCEL_00883	1.32e-41	154.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,36FJB@31979|Clostridiaceae	186801|Clostridia	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_1112418_1	392500.Swoo_0313	1.35e-96	297.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2QAYJ@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1169214_1	224324.aq_563	2.6e-08	54.7	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,RHH_3,dCache_1
k59_1169214_2	563040.Saut_0378	1.44e-74	230.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,42RAQ@68525|delta/epsilon subdivisions,2YPDH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k59_546942_1	1197477.IA57_00805	1.28e-167	488.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_546942_2	1380600.AUYN01000001_gene2707	1.08e-199	556.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_546942_3	1380600.AUYN01000001_gene2708	1.41e-115	345.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
k59_1564205_1	1237149.C900_04356	2.07e-48	174.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia	976|Bacteroidetes	KMT	PFAM BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
k59_1564208_2	1298593.TOL_0077	3.97e-64	200.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales	135619|Oceanospirillales	C	COG2863 Cytochrome c553	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_603063_1	768066.HELO_2646	2.2e-73	235.0	COG4626@1|root,COG4626@2|Bacteria,1R2FH@1224|Proteobacteria,1RN1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1678681_1	203119.Cthe_1472	5.88e-53	196.0	COG2730@1|root,COG4124@1|root,COG2730@2|Bacteria,COG4124@2|Bacteria,1U8S3@1239|Firmicutes,24CGR@186801|Clostridia,3WHKP@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 26	celH	GO:0003674,GO:0003824,GO:0004553,GO:0008810,GO:0016787,GO:0016798	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Dockerin_1,Glyco_hydro_26
k59_941222_1	396588.Tgr7_1053	1.69e-37	135.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,1RS8P@1236|Gammaproteobacteria,1WZUJ@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	Thioredoxin_5
k59_832419_1	1121931.AUHG01000018_gene1342	1.65e-67	224.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1HYKS@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
k59_995285_1	572480.Arnit_2922	7.59e-44	169.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_832426_1	1280664.AUIX01000023_gene896	5.26e-10	65.9	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,4BYI4@830|Butyrivibrio	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DegV,HATPase_c,HisKA,Hpt,MASE3,Response_reg,dCache_1
k59_435874_1	1197477.IA57_00505	3.25e-112	327.0	COG2819@1|root,COG2819@2|Bacteria,4NGAG@976|Bacteroidetes,1HZR3@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_1451376_1	653733.Selin_0624	1.37e-32	130.0	COG2199@1|root,COG2202@1|root,COG3437@1|root,COG3829@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	2.7.13.3	ko:K02482,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CHASE,EAL,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_662248_1	563040.Saut_1958	1.32e-91	291.0	COG2887@1|root,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_682338_2	1267535.KB906767_gene4991	3.31e-14	72.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,3Y2X1@57723|Acidobacteria,2JHYG@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
k59_399702_1	768671.ThimaDRAFT_1155	1.35e-109	322.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_342564_1	367737.Abu_0317	1.51e-19	87.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_342564_2	572480.Arnit_2651	1.85e-60	196.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_117090_1	1121931.AUHG01000016_gene1114	4.08e-50	171.0	COG0420@1|root,COG0420@2|Bacteria,4NEET@976|Bacteroidetes,1HYF2@117743|Flavobacteriia	976|Bacteroidetes	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k59_117090_2	655815.ZPR_2878	1.63e-65	222.0	COG0419@1|root,COG0419@2|Bacteria,4NH9H@976|Bacteroidetes,1HYCM@117743|Flavobacteriia	976|Bacteroidetes	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_173849_1	1168067.JAGP01000001_gene1502	1.14e-75	227.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,460J9@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_1246249_2	1168067.JAGP01000001_gene2115	4.06e-08	56.2	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,460MW@72273|Thiotrichales	72273|Thiotrichales	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1359215_1	1380600.AUYN01000001_gene2286	1.83e-184	534.0	COG5434@1|root,COG5434@2|Bacteria,4NKHU@976|Bacteroidetes,1I0UA@117743|Flavobacteriia	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_342579_1	1121931.AUHG01000010_gene561	1.2e-98	301.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_4181_1	411154.GFO_2786	2.74e-41	144.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,1HXDI@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_399723_2	1123517.JOMR01000001_gene703	1.94e-187	530.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	BQ	COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_399723_3	90813.JQMT01000001_gene1911	1.42e-10	63.5	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,460MD@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_1642544_1	929558.SMGD1_1028	2.05e-114	332.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,42YWZ@68525|delta/epsilon subdivisions,2YRHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_1642544_2	563040.Saut_2022	4.68e-53	176.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2YR6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ecdysteroid kinase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_1698776_2	504487.JCM19302_3139	1.15e-153	434.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1HX8Z@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1698776_3	504487.JCM19302_3138	2.32e-62	198.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,1HXF0@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_230327_1	90814.KL370891_gene1720	1.34e-121	359.0	2DNAT@1|root,32WH7@2|Bacteria,1N2AT@1224|Proteobacteria,1SIPZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_230327_2	1123517.JOMR01000001_gene526	2.5e-13	71.2	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,1SFE3@1236|Gammaproteobacteria,461HT@72273|Thiotrichales	72273|Thiotrichales	NU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1133826_1	760154.Sulba_1005	7.28e-67	227.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02030,ko:K07679	ko02020,ko05133,map02020,map05133	M00236,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
k59_1189681_1	713587.THITH_16220	5.93e-37	140.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1T4WG@1236|Gammaproteobacteria,1X2TZ@135613|Chromatiales	135613|Chromatiales	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_173897_1	1380600.AUYN01000009_gene1737	1.95e-73	236.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_399755_1	323850.Shew_2795	2.29e-102	308.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,2QAA9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Xanthine uracil vitamin C permease	yjcD	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k59_1133836_1	90814.KL370891_gene1844	1.63e-55	177.0	2F4JC@1|root,33X92@2|Bacteria,1NWG8@1224|Proteobacteria,1SPMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1133836_2	90814.KL370891_gene1843	2.48e-73	234.0	COG0369@1|root,COG0369@2|Bacteria,1QUAH@1224|Proteobacteria,1T1RJ@1236|Gammaproteobacteria,460VY@72273|Thiotrichales	72273|Thiotrichales	P	Oxidoreductase NAD-binding domain	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,NAD_binding_1
k59_795148_1	215803.DB30_5174	5.5e-05	50.8	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,1PEIB@1224|Proteobacteria,439WA@68525|delta/epsilon subdivisions,2X5AJ@28221|Deltaproteobacteria,2YWZV@29|Myxococcales	28221|Deltaproteobacteria	N	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
k59_1246312_2	563040.Saut_2141	2.52e-86	272.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1133849_1	1380600.AUYN01000009_gene1172	6.12e-138	402.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_1076759_1	1123514.KB905899_gene468	1.67e-32	125.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,462R8@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1076759_2	1123514.KB905899_gene467	5.56e-104	312.0	COG0564@1|root,COG0564@2|Bacteria,1R4IN@1224|Proteobacteria,1S0WR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Pseudouridine synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_1076759_4	1123518.ARWI01000001_gene2067	9.27e-103	304.0	COG0847@1|root,COG0847@2|Bacteria,1MXM2@1224|Proteobacteria,1T2MD@1236|Gammaproteobacteria,462WC@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_401139_3	1484460.JSWG01000010_gene3194	5.95e-132	385.0	COG1376@1|root,COG1376@2|Bacteria,4NEE0@976|Bacteroidetes,1HXKU@117743|Flavobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
k59_401139_4	1178825.ALIH01000006_gene1565	1.35e-100	296.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_1360523_1	1223410.KN050846_gene636	1.12e-118	344.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
k59_5399_2	1182590.BN5_02590	6.89e-13	70.5	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1YI59@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	TLL0138	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_1305270_1	1278309.KB907108_gene1587	1.07e-23	99.0	28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,1T4JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1305270_2	1278309.KB907108_gene1586	1.7e-66	214.0	2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria,1XNQZ@135619|Oceanospirillales	135619|Oceanospirillales	S	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_401146_1	411154.GFO_3163	9.58e-42	146.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HX79@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_401146_2	985255.APHJ01000021_gene1657	5.53e-83	247.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1I263@117743|Flavobacteriia,2P6T3@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1022580_1	391587.KAOT1_16738	1.19e-159	452.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1022580_2	641526.ADIWIN_2501	3.47e-15	70.1	2E7YU@1|root,332D8@2|Bacteria,4NV36@976|Bacteroidetes,1I554@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1022580_3	504487.JCM19302_4137	1.51e-58	192.0	COG3146@1|root,COG3146@2|Bacteria,4NI7H@976|Bacteroidetes,1I0KW@117743|Flavobacteriia	976|Bacteroidetes	S	8-amino-7-oxononanoate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB_like
k59_1417706_1	411154.GFO_3564	4.69e-112	325.0	COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,1I1ME@117743|Flavobacteriia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
k59_1078121_1	1121285.AUFK01000002_gene19	1.31e-66	221.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1HZUG@117743|Flavobacteriia	976|Bacteroidetes	L	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
k59_1700216_1	1353276.JADR01000001_gene462	2.26e-43	154.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,1HXR0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k59_1700216_2	1380600.AUYN01000009_gene2164	1.58e-158	456.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,1HX5V@117743|Flavobacteriia	976|Bacteroidetes	HQ	Isochorismate synthase	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
k59_1700216_3	1380600.AUYN01000009_gene2163	3.94e-81	242.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1I2BT@117743|Flavobacteriia	976|Bacteroidetes	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
k59_1700216_4	1197477.IA57_12160	4.09e-88	265.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,1HZK4@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
k59_796596_1	1123517.JOMR01000001_gene1795	3.82e-24	99.4	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_796596_2	1123514.KB905899_gene1759	5.06e-82	257.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,4606G@72273|Thiotrichales	72273|Thiotrichales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_513565_1	411154.GFO_1619	4.78e-101	300.0	2DBAY@1|root,2Z84S@2|Bacteria,4NGXD@976|Bacteroidetes,1HXHD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
k59_344055_1	1123037.AUDE01000029_gene1564	5.43e-42	140.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1I18G@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_344055_2	1121912.AUHD01000001_gene2422	5.25e-118	338.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1HWPB@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_62242_1	1123514.KB905899_gene1493	4.12e-77	244.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,45ZYV@72273|Thiotrichales	72273|Thiotrichales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_62242_2	1122139.KB907884_gene401	0.000799	41.2	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1XJZ1@135619|Oceanospirillales	135619|Oceanospirillales	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_401176_1	504487.JCM19302_56	9.78e-158	456.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HXGY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_401176_2	1347342.BN863_13860	4.68e-110	322.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1756908_1	376686.Fjoh_2012	5.7e-146	438.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2NSP5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_739877_1	1123518.ARWI01000001_gene742	6.9e-38	134.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,460DU@72273|Thiotrichales	72273|Thiotrichales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k59_739877_2	1123518.ARWI01000001_gene746	1.09e-158	447.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,45ZQJ@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_739877_3	391589.RGAI101_3937	1.79e-83	300.0	COG1352@1|root,COG2201@1|root,COG3852@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3852@2|Bacteria,1NQTI@1224|Proteobacteria	1224|Proteobacteria	NT	Chemotaxis	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HWE_HK,HisKA,HisKA_3,PAS_10,PAS_4,PAS_9,Response_reg
k59_1305321_1	411154.GFO_2246	1.16e-05	45.1	COG2198@1|root,COG2198@2|Bacteria,4NVS6@976|Bacteroidetes,1I5MU@117743|Flavobacteriia	976|Bacteroidetes	T	(Hpt) domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_1305321_2	1121931.AUHG01000011_gene2136	3.21e-116	343.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_627119_1	1185766.DL1_13780	2.48e-133	388.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2XMKS@285107|Thioclava	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_1305327_1	522306.CAP2UW1_0311	3.22e-105	319.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,1KPNU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_1022635_1	572480.Arnit_1615	2.82e-94	288.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,42PS0@68525|delta/epsilon subdivisions,2YMQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M20
k59_5457_1	563040.Saut_0695	6.09e-111	328.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2YMU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_1135108_1	572480.Arnit_2977	1.02e-126	365.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2YN6R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_231916_1	1565129.JSFF01000026_gene1234	1.76e-45	158.0	COG3210@1|root,COG3210@2|Bacteria,1QXF2@1224|Proteobacteria,1T3A4@1236|Gammaproteobacteria,2QETX@267890|Shewanellaceae	1236|Gammaproteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_288142_1	1122225.AULQ01000012_gene414	5.73e-119	345.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_288142_2	504487.JCM19302_1779	2e-99	290.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_288142_3	1347342.BN863_27090	1.06e-54	174.0	2AVDM@1|root,31M58@2|Bacteria,4NUN6@976|Bacteroidetes,1I278@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
k59_1587547_1	1348657.M622_10990	4.61e-50	159.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,2KXFI@206389|Rhodocyclales	206389|Rhodocyclales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1305330_1	616991.JPOO01000003_gene2346	1.09e-160	466.0	COG1524@1|root,COG1524@2|Bacteria,4NIUS@976|Bacteroidetes,1HZKJ@117743|Flavobacteriia,23HQN@178469|Arenibacter	976|Bacteroidetes	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
k59_1305330_2	504472.Slin_3399	1.62e-140	422.0	COG0521@1|root,COG0521@2|Bacteria,4NG3I@976|Bacteroidetes,47JEA@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
k59_1305330_3	1123277.KB893191_gene2934	1.38e-111	360.0	COG4206@1|root,COG4206@2|Bacteria,4PNAG@976|Bacteroidetes,47YAC@768503|Cytophagia	976|Bacteroidetes	H	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1473975_1	1380600.AUYN01000007_gene3145	2.1e-72	220.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1I23R@117743|Flavobacteriia	976|Bacteroidetes	S	(GNAT) family	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_1473975_2	1178825.ALIH01000003_gene2253	7.66e-28	108.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1HXN8@117743|Flavobacteriia	976|Bacteroidetes	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_175420_1	90814.KL370891_gene857	0.0	1775.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_175420_2	400668.Mmwyl1_4035	6.95e-29	112.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XHDH@135619|Oceanospirillales	135619|Oceanospirillales	F	carbamoyl-phosphate synthetase glutamine chain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1530418_1	1178825.ALIH01000001_gene2685	1.69e-64	203.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
k59_196156_1	1123514.KB905899_gene1055	2.66e-87	285.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales	72273|Thiotrichales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1437329_1	1121912.AUHD01000015_gene1124	8.98e-46	154.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,1HWXJ@117743|Flavobacteriia	976|Bacteroidetes	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
k59_1437329_2	983544.Lacal_0635	1.86e-45	153.0	COG1216@1|root,COG1216@2|Bacteria,4PKP2@976|Bacteroidetes,1IJFG@117743|Flavobacteriia	976|Bacteroidetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_196158_1	1356852.N008_13495	6.17e-16	77.8	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,47JBI@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1380446_1	1565129.JSFF01000032_gene1345	1.54e-174	504.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,2Q9TR@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase M13, neprilysin	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_1609091_1	1042377.AFPJ01000036_gene1227	1.68e-182	523.0	COG3538@1|root,COG3538@2|Bacteria,1MXZA@1224|Proteobacteria,1RXFA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
k59_1609091_2	869213.JCM21142_183	2.7e-253	721.0	COG2361@1|root,COG2361@2|Bacteria,4PKES@976|Bacteroidetes	976|Bacteroidetes	S	Glycoside hydrolase 97	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
k59_1609091_3	1144313.PMI10_03515	0.0	1534.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NTRC@237|Flavobacterium	976|Bacteroidetes	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
k59_1609091_4	1144313.PMI10_03514	0.0	1225.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NUCP@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_1609091_5	1144313.PMI10_03513	1.19e-64	210.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HXEA@117743|Flavobacteriia,2NTF3@237|Flavobacterium	976|Bacteroidetes	G	Pfam Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
k59_1268312_1	929558.SMGD1_2116	2.89e-76	248.0	COG1196@1|root,COG1196@2|Bacteria,1QEEI@1224|Proteobacteria,43DPF@68525|delta/epsilon subdivisions,2YRNC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_759596_1	1249480.B649_11540	2.29e-121	372.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_1437345_1	1415778.JQMM01000001_gene477	1.89e-91	282.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1J55B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_2885	Glu_cys_ligase
k59_1437351_1	1537917.JU82_02990	6.47e-50	165.0	COG0704@1|root,COG0704@2|Bacteria,1Q5TJ@1224|Proteobacteria,42STN@68525|delta/epsilon subdivisions,2YPRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PhoU family	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_198143_2	1448139.AI20_11910	1.33e-14	73.6	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,1Y4Q1@135624|Aeromonadales	135624|Aeromonadales	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k59_1722902_1	323850.Shew_2352	1.54e-41	139.0	2EM8V@1|root,33EY0@2|Bacteria,1NBBF@1224|Proteobacteria,1SVSX@1236|Gammaproteobacteria,2QCUQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3135
k59_536377_1	1123228.AUIH01000041_gene2959	1.94e-65	224.0	COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1XRVI@135619|Oceanospirillales	135619|Oceanospirillales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
k59_423548_1	326298.Suden_0149	7.42e-61	189.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,42TRM@68525|delta/epsilon subdivisions,2YQ2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1393 Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_423548_2	326298.Suden_1537	2.09e-30	113.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,42RG9@68525|delta/epsilon subdivisions,2YMVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transcriptional regulator, ModE family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_85064_1	411154.GFO_2528	1.52e-112	331.0	COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,1HX8R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_592550_1	1121875.KB907547_gene3142	9.06e-71	216.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_592550_2	313603.FB2170_07949	3.1e-78	242.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
k59_875224_1	1380600.AUYN01000009_gene1127	1.01e-08	55.5	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_875224_2	1123037.AUDE01000001_gene1926	2.5e-39	163.0	COG1345@1|root,COG2356@1|root,COG3420@1|root,COG4733@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LTD
k59_423569_2	266117.Rxyl_2496	1.84e-44	163.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
k59_1552039_1	1123518.ARWI01000001_gene1180	3.86e-08	54.3	COG1560@1|root,COG1560@2|Bacteria,1PHNN@1224|Proteobacteria,1RXSV@1236|Gammaproteobacteria,463FF@72273|Thiotrichales	72273|Thiotrichales	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_1552039_2	1123518.ARWI01000001_gene1181	3.56e-141	403.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,45ZYE@72273|Thiotrichales	72273|Thiotrichales	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_1156739_1	1353276.JADR01000005_gene2576	1.89e-167	476.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1HWV8@117743|Flavobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1328666_1	1236959.BAMT01000001_gene1367	4.86e-61	210.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KM09@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,Response_reg
k59_1722948_1	411154.GFO_2788	2.77e-85	254.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1722948_2	411154.GFO_2787	8.67e-36	132.0	2E4WE@1|root,32ZQI@2|Bacteria,4NURF@976|Bacteroidetes,1I5C9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_930962_1	930169.B5T_02397	2.54e-58	200.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_708138_1	1123326.JFBL01000007_gene550	1.15e-70	219.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42RBS@68525|delta/epsilon subdivisions,2YP0S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	sensor protein	cetB	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_198207_1	62928.azo1420	8.65e-112	327.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,2KXUE@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
k59_1439354_1	504487.JCM19302_295	6.49e-82	247.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCS@117743|Flavobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1439354_2	1137281.D778_01237	4.93e-13	67.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1HX5Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	with different specificities (Related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_423613_1	946077.W5A_10467	1.64e-90	286.0	28MEY@1|root,2ZASH@2|Bacteria,4NG12@976|Bacteroidetes,1I8JG@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_1780261_2	653733.Selin_1914	3.93e-15	81.6	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1666522_1	326298.Suden_1852	1.3e-159	470.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2YNGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2,Viral_helicase1
k59_1206150_1	865937.Gilli_1066	4.28e-26	106.0	28J74@1|root,2Z92M@2|Bacteria,4NJFE@976|Bacteroidetes,1HYFB@117743|Flavobacteriia,2P73M@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1206150_2	590409.Dd586_0658	4.13e-09	58.9	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,2JD1P@204037|Dickeya	1236|Gammaproteobacteria	M	Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	-	-	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_1044789_1	1122225.AULQ01000006_gene917	2.42e-235	669.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_255252_1	1380600.AUYN01000007_gene3309	4.54e-21	89.4	COG3047@1|root,COG3047@2|Bacteria,4NH9T@976|Bacteroidetes,1HYYP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_255252_2	504487.JCM19302_2788	3.31e-145	419.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_1328724_1	1178825.ALIH01000009_gene1334	2.86e-120	368.0	COG4783@1|root,COG4783@2|Bacteria,4PMBD@976|Bacteroidetes,1IJQH@117743|Flavobacteriia	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_1156804_1	572480.Arnit_0767	8.41e-181	528.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1206157_1	998674.ATTE01000001_gene1886	8.82e-08	57.8	COG3291@1|root,COG4886@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,1NFXF@1224|Proteobacteria,1T5FG@1236|Gammaproteobacteria,4638P@72273|Thiotrichales	2|Bacteria	M	domain protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,DUF5011,F5_F8_type_C,Flg_new,LRR_5,Laminin_G_3,NPCBM,Peptidase_M60,SLH
k59_1270442_1	326298.Suden_1023	9.5e-92	285.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_1270442_2	709032.Sulku_1014	7.36e-10	58.2	COG2267@1|root,COG2267@2|Bacteria,1Q0VR@1224|Proteobacteria,42SJB@68525|delta/epsilon subdivisions,2YPM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1666538_1	1123514.KB905899_gene680	1.85e-132	388.0	COG0833@1|root,COG0833@2|Bacteria,1QTSM@1224|Proteobacteria,1RNI2@1236|Gammaproteobacteria,4627A@72273|Thiotrichales	72273|Thiotrichales	E	Amino acid permease	-	-	-	ko:K11733	-	-	-	-	ko00000,ko02000	2.A.3.1.2	-	-	AA_permease
k59_1100264_1	572480.Arnit_0907	7.85e-52	166.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2YPGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k59_1100264_2	572480.Arnit_0908	5.48e-73	225.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1328745_1	469596.HMPREF9488_03445	1.03e-09	60.5	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,3VNRV@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Response regulator receiver domain protein	cssR	-	-	ko:K07770	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1328745_2	929558.SMGD1_2077	2.71e-83	255.0	COG0642@1|root,COG0642@2|Bacteria,1QZ1Z@1224|Proteobacteria,42SN7@68525|delta/epsilon subdivisions,2YPK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_366138_1	1122207.MUS1_02035	1.81e-61	200.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1XIUZ@135619|Oceanospirillales	135619|Oceanospirillales	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
k59_366138_2	312309.VF_A0049	6.9e-08	50.8	COG0640@1|root,COG0640@2|Bacteria,1QM6B@1224|Proteobacteria,1TJEB@1236|Gammaproteobacteria,1Y13T@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
k59_1723030_1	1565129.JSFF01000013_gene286	5.19e-53	176.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,2Q9MP@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_198272_1	1123518.ARWI01000001_gene1508	1.09e-92	284.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,45ZNS@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_198272_3	1123518.ARWI01000001_gene1510	9.18e-150	427.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,4602J@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_198272_4	1123518.ARWI01000001_gene1517	2.17e-13	67.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria,463C1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_820152_2	1166018.FAES_3085	3.24e-15	74.7	COG3431@1|root,COG3431@2|Bacteria,4NVP3@976|Bacteroidetes,47RXP@768503|Cytophagia	976|Bacteroidetes	S	Sensors of blue-light using FAD	pacB	-	-	-	-	-	-	-	-	-	-	-	BLUF
k59_820152_3	709032.Sulku_2433	3.14e-90	276.0	COG1879@1|root,COG1879@2|Bacteria,1R1K9@1224|Proteobacteria,43DAQ@68525|delta/epsilon subdivisions,2YR56@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_85219_1	1121931.AUHG01000010_gene75	5.24e-242	699.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1206187_1	1415754.JQMK01000013_gene224	2.18e-54	180.0	COG2267@1|root,COG2267@2|Bacteria,1R4YR@1224|Proteobacteria,1S1JB@1236|Gammaproteobacteria,468TQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_310865_1	926559.JoomaDRAFT_1169	6.36e-251	699.0	COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,1HZNM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_423696_1	1380600.AUYN01000001_gene2374	0.0	1060.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_423696_2	1121912.AUHD01000001_gene2821	3.2e-79	239.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1I2CM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_423696_3	1178825.ALIH01000006_gene1430	3.67e-175	509.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1HX0J@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_1439459_1	1232410.KI421421_gene3588	4.05e-26	105.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1439459_2	338963.Pcar_1937	8.03e-50	162.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_1611376_1	1178825.ALIH01000001_gene2536	2.83e-43	154.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_1100336_1	563040.Saut_1812	9.54e-56	176.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_820208_1	572480.Arnit_1679	5.38e-37	137.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_1723118_1	1123518.ARWI01000001_gene1990	1.76e-114	330.0	COG3439@1|root,COG3439@2|Bacteria,1REDZ@1224|Proteobacteria,1S935@1236|Gammaproteobacteria,461JP@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_875409_1	1123517.JOMR01000001_gene1440	5.29e-168	477.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S0BJ@1236|Gammaproteobacteria,460IC@72273|Thiotrichales	72273|Thiotrichales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1328839_1	411154.GFO_0200	1.36e-21	92.4	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HWPI@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_1328839_2	1121931.AUHG01000010_gene854	1.26e-72	231.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
k59_1044907_1	1121931.AUHG01000001_gene3115	6.26e-45	151.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,1HY5I@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
k59_1044907_2	411154.GFO_1902	5.83e-46	157.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1HWZT@117743|Flavobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_1328841_1	572480.Arnit_2292	2.72e-201	570.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_875419_1	425104.Ssed_1333	6.57e-47	154.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,2QA3I@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_708333_1	1168067.JAGP01000001_gene2073	6.22e-57	194.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales	72273|Thiotrichales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_708333_2	94122.Shewana3_0125	4.06e-19	87.8	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,2QAWE@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5638	Chor_lyase
k59_1611432_1	313594.PI23P_07465	8.48e-22	94.4	COG3637@1|root,COG3637@2|Bacteria,4PKKK@976|Bacteroidetes,1HYEJ@117743|Flavobacteriia,3VWEG@52959|Polaribacter	976|Bacteroidetes	M	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
k59_140559_1	1380600.AUYN01000002_gene3	1.66e-151	472.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_296800_1	1178825.ALIH01000009_gene1292	1.12e-249	689.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1HX73@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_1426060_1	323850.Shew_0871	1.46e-103	308.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,2Q9MB@267890|Shewanellaceae	1236|Gammaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_71266_1	90814.KL370891_gene1490	6.13e-126	365.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,46083@72273|Thiotrichales	72273|Thiotrichales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_71266_2	1123514.KB905899_gene1194	2.76e-120	353.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,1RY1W@1236|Gammaproteobacteria,463XA@72273|Thiotrichales	72273|Thiotrichales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_352537_1	1158338.JNLJ01000001_gene1096	3.66e-12	68.9	COG3746@1|root,COG3746@2|Bacteria,2G5GC@200783|Aquificae	200783|Aquificae	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
k59_1483128_1	411154.GFO_3243	1.32e-170	483.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_1368934_1	1123518.ARWI01000001_gene1045	0.0	931.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_693075_1	94122.Shewana3_3510	7.42e-26	99.0	COG1438@1|root,COG1438@2|Bacteria,1N2AF@1224|Proteobacteria,1RSF7@1236|Gammaproteobacteria,2Q8GX@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
k59_693075_2	1565129.JSFF01000002_gene3550	8.25e-22	92.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,2Q8VD@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM Dyp-type peroxidase family	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
k59_1196396_1	1121912.AUHD01000001_gene2780	2.07e-227	635.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1196396_2	504487.JCM19302_1033	6.64e-12	62.8	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,1I199@117743|Flavobacteriia	976|Bacteroidetes	I	Acyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_296841_1	572480.Arnit_2222	2.82e-34	120.0	2AJSI@1|root,31AEV@2|Bacteria,1Q5GJ@1224|Proteobacteria,4317Q@68525|delta/epsilon subdivisions,2YS8K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1483140_1	1123514.KB905899_gene1963	5.39e-12	63.2	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,45ZPZ@72273|Thiotrichales	72273|Thiotrichales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
k59_1483140_2	1123518.ARWI01000001_gene1213	6.42e-126	361.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,460FG@72273|Thiotrichales	72273|Thiotrichales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_917682_1	90813.JQMT01000001_gene898	1.15e-168	483.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,4605R@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_805463_1	411154.GFO_3464	2.31e-120	356.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1HZGJ@117743|Flavobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_805463_2	411154.GFO_3465	4.03e-57	196.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
k59_296848_1	1121889.AUDM01000008_gene729	1.5e-99	310.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes,1I1N3@117743|Flavobacteriia,2NSZF@237|Flavobacterium	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_805465_2	1178825.ALIH01000001_gene2355	1.43e-39	139.0	COG0810@1|root,COG0810@2|Bacteria,4NN8A@976|Bacteroidetes,1I18J@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_748267_1	90814.KL370891_gene198	7.17e-19	82.8	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,460T0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_748267_2	317025.Tcr_0262	1.57e-115	337.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,4607J@72273|Thiotrichales	72273|Thiotrichales	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_1256559_1	572480.Arnit_0699	8.88e-45	149.0	COG0727@1|root,COG0727@2|Bacteria,1Q2XT@1224|Proteobacteria,42WFK@68525|delta/epsilon subdivisions,2YQMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_1256559_2	572480.Arnit_0700	3.7e-45	159.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_13638_1	944546.ABED_0736	1.79e-40	151.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42QY3@68525|delta/epsilon subdivisions,2YNZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,MCPsignal,dCache_1,dCache_2,sCache_2
k59_972377_1	317025.Tcr_1975	1.3e-86	276.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,461PA@72273|Thiotrichales	72273|Thiotrichales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_1483156_1	745718.JADT01000005_gene80	2.63e-44	149.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_1483156_2	641526.ADIWIN_0415	1.33e-116	340.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_184425_1	1380600.AUYN01000007_gene3322	3.56e-234	650.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,1HX8M@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
k59_1538701_1	391587.KAOT1_08503	2.37e-40	148.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1538701_2	983544.Lacal_0028	4.38e-11	63.2	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1196422_1	411154.GFO_1970	4.75e-100	313.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k59_579488_1	1123514.KB905901_gene181	6.24e-54	195.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,460QS@72273|Thiotrichales	72273|Thiotrichales	S	TIGRFAM TIGR02099 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_1709266_1	411154.GFO_1563	8.52e-49	177.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWPC@117743|Flavobacteriia	976|Bacteroidetes	M	Cell envelope biogenesis protein AsmA	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_127015_1	1232410.KI421412_gene127	7.54e-71	226.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2WJRJ@28221|Deltaproteobacteria,43S9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	alpha/beta hydrolase fold	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
k59_1596664_1	1237149.C900_03123	5.91e-41	148.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
k59_1596664_2	1237149.C900_03124	1.77e-46	157.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
k59_240851_1	1123518.ARWI01000001_gene1731	3.12e-150	463.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_240851_2	1123518.ARWI01000001_gene1730	1.96e-156	449.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_861459_1	929558.SMGD1_1216	8.63e-79	245.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YQ8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_917717_1	1380600.AUYN01000003_gene146	2.58e-176	501.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1HWKX@117743|Flavobacteriia	976|Bacteroidetes	GM	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_917717_2	1178825.ALIH01000005_gene344	4.97e-89	276.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia	976|Bacteroidetes	C	dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_693141_1	1237149.C900_05787	4.95e-10	63.9	COG0577@1|root,COG0577@2|Bacteria,4P1B0@976|Bacteroidetes,47U89@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	MacB_PCD
k59_1652810_1	1380600.AUYN01000001_gene2438	6.81e-109	316.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1652810_2	1178825.ALIH01000002_gene1008	1.34e-23	97.1	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_71365_1	504487.JCM19302_3900	1.08e-76	237.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_522566_1	929558.SMGD1_1797	1.26e-30	111.0	2AVG9@1|root,31M8F@2|Bacteria,1QJ39@1224|Proteobacteria,42W1H@68525|delta/epsilon subdivisions,2YQB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_522566_2	929558.SMGD1_1798	1.26e-52	174.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42RBN@68525|delta/epsilon subdivisions,2YP23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_184481_1	572480.Arnit_2336	5.72e-46	152.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2YNYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_184481_2	944546.ABED_1475	3.57e-27	109.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_1256639_1	1123518.ARWI01000001_gene649	3.8e-108	320.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,460ER@72273|Thiotrichales	72273|Thiotrichales	T	Chemotaxis protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_805559_1	1121931.AUHG01000011_gene2051	9.42e-114	348.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_861513_1	90814.KL370891_gene1745	1.05e-116	362.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,45ZVX@72273|Thiotrichales	72273|Thiotrichales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_1256646_1	376686.Fjoh_2035	2.14e-87	266.0	COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,1HZX4@117743|Flavobacteriia,2NU3E@237|Flavobacterium	976|Bacteroidetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_71388_1	1380600.AUYN01000007_gene3252	6.08e-240	663.0	COG2865@1|root,COG2865@2|Bacteria,4NEF5@976|Bacteroidetes,1HYUG@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM Divergent AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
k59_71388_2	1121912.AUHD01000003_gene2972	7.54e-144	410.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_71388_3	1107311.Q767_08285	3.27e-33	126.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia,2NVIV@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
k59_805574_2	944547.ABLL_0508	2.98e-48	175.0	COG0642@1|root,COG3287@1|root,COG0642@2|Bacteria,COG3287@2|Bacteria,1NXDJ@1224|Proteobacteria,43CBD@68525|delta/epsilon subdivisions,2YQE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA
k59_636197_1	1313301.AUGC01000021_gene1226	1.4e-31	117.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes	976|Bacteroidetes	O	Fe-S assembly ATPase, SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_636197_2	491952.Mar181_2457	8.87e-64	207.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1XHSV@135619|Oceanospirillales	135619|Oceanospirillales	O	Cysteine desulfurase activator complex subunit SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_296965_1	572480.Arnit_2534	6.83e-25	99.8	COG0745@1|root,COG0745@2|Bacteria,1Q5S3@1224|Proteobacteria,42ZUW@68525|delta/epsilon subdivisions,2YRV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_296965_2	572480.Arnit_2535	2.28e-18	85.9	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42PU8@68525|delta/epsilon subdivisions	1224|Proteobacteria	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
k59_240930_1	497321.C664_02715	1.51e-124	364.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,2KUWH@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1031221_1	1123234.AUKI01000013_gene1576	7.5e-37	130.0	COG3637@1|root,COG3637@2|Bacteria,4NI8B@976|Bacteroidetes,1HZ9J@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1031221_2	313603.FB2170_09446	1.25e-79	244.0	COG2259@1|root,COG2259@2|Bacteria,4NK73@976|Bacteroidetes,1I0YP@117743|Flavobacteriia	976|Bacteroidetes	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1258373_2	313603.FB2170_08829	6.38e-65	198.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1I2UP@117743|Flavobacteriia,2PHD0@252356|Maribacter	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_468536_1	317025.Tcr_0170	0.000276	42.0	COG2391@1|root,COG2391@2|Bacteria,1PBU0@1224|Proteobacteria,1SWII@1236|Gammaproteobacteria,4627V@72273|Thiotrichales	72273|Thiotrichales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_468536_2	90814.KL370891_gene106	4.44e-92	271.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_1598468_1	572480.Arnit_1832	4.44e-71	244.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_1032870_1	563040.Saut_0554	4.9e-70	226.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2YTQ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1032870_2	929558.SMGD1_0425	3.94e-34	128.0	28NUA@1|root,2ZBSQ@2|Bacteria,1QE31@1224|Proteobacteria,42Z7U@68525|delta/epsilon subdivisions,2YR9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73101_1	572480.Arnit_0652	1.05e-191	544.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2YM9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_186255_1	326298.Suden_1783	1.89e-52	181.0	COG1413@1|root,COG1413@2|Bacteria,1Q1TE@1224|Proteobacteria,42UC8@68525|delta/epsilon subdivisions,2YPXK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1370767_1	572480.Arnit_1795	1.78e-85	280.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_1427858_1	929558.SMGD1_1870	8.45e-60	209.0	COG2199@1|root,COG2200@1|root,COG4753@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,COG4753@2|Bacteria,1R7HC@1224|Proteobacteria,42RY7@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
k59_807344_1	317025.Tcr_0455	5.29e-33	127.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_807344_2	90814.KL370891_gene1660	7.53e-32	121.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,1SYRU@1236|Gammaproteobacteria,460YA@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1197771_1	1380600.AUYN01000007_gene3125	1.24e-36	136.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1197771_2	391603.FBALC1_00185	2.3e-132	383.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_73114_1	1123228.AUIH01000007_gene2594	9.07e-121	360.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XHGY@135619|Oceanospirillales	135619|Oceanospirillales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_637895_1	1123518.ARWI01000001_gene1186	7.61e-261	749.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales	72273|Thiotrichales	E	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_637899_1	1232410.KI421428_gene1224	1.03e-113	360.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43S5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	RNA polymerase I subunit A N-terminus	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1427870_1	999419.HMPREF1077_02533	7.47e-44	154.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,2FM99@200643|Bacteroidia,22XQ2@171551|Porphyromonadaceae	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
k59_186285_2	326298.Suden_2033	1.11e-47	166.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2YMTY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Mg chelatase-related protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1370804_1	1123518.ARWI01000001_gene998	1.11e-146	444.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1144921_1	391603.FBALC1_12097	5.96e-115	334.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1HXF5@117743|Flavobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
k59_1144921_2	641526.ADIWIN_2211	2.07e-52	168.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,1I24Y@117743|Flavobacteriia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_1316289_1	1121931.AUHG01000010_gene498	1.5e-44	158.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
k59_1316289_2	1121931.AUHG01000010_gene499	1.6e-79	240.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia	976|Bacteroidetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_973738_1	1042377.AFPJ01000004_gene374	4.41e-09	62.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,46AB4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG2909 ATP-dependent transcriptional regulator	malT	GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
k59_1316294_1	1121931.AUHG01000012_gene2649	1.17e-113	335.0	COG3021@1|root,COG3021@2|Bacteria,4NGD4@976|Bacteroidetes,1HYZ5@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1197808_1	388413.ALPR1_02205	2.22e-65	226.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
k59_1444138_2	1565129.JSFF01000001_gene1008	3.79e-18	79.0	2CEIZ@1|root,33JKV@2|Bacteria,1NMVX@1224|Proteobacteria,1SB27@1236|Gammaproteobacteria,2QCWX@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_315849_1	323850.Shew_1831	8.01e-141	410.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,2Q8Q5@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM SpoVR family protein	ycgB	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_1275311_1	1348583.ATLH01000001_gene3720	1.34e-70	237.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1105148_1	90814.KL370891_gene705	4.98e-115	337.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,461Y8@72273|Thiotrichales	72273|Thiotrichales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_371083_1	76114.ebA6270	3.57e-99	309.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria,2KVYB@206389|Rhodocyclales	206389|Rhodocyclales	CK	FMN_bind	-	-	-	ko:K19339	-	-	-	-	ko00000,ko03000	-	-	-	Fer4_5
k59_1209117_1	1499686.BN1079_01945	1.49e-111	332.0	COG0451@1|root,COG1898@1|root,COG0451@2|Bacteria,COG1898@2|Bacteria,1MXGB@1224|Proteobacteria,1RSK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	fnlB	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_1333990_1	572480.Arnit_0956	1.78e-77	234.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,430PA@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_597183_1	338966.Ppro_2611	9.54e-18	87.8	COG2202@1|root,COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PJW@68525|delta/epsilon subdivisions,2WJQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_315892_1	1380600.AUYN01000001_gene2265	1.19e-104	313.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1HWSR@117743|Flavobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_1556965_1	367737.Abu_0813	1.91e-81	268.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_654844_1	1382358.JHVN01000007_gene302	7.25e-32	115.0	292H0@1|root,2ZQ15@2|Bacteria,1VGV2@1239|Firmicutes,4HQ9X@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1556966_1	1453500.AT05_05250	1.11e-17	89.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CHU_C,PKD,Peptidase_S8,fn3
k59_1105173_1	387093.SUN_0858	9.23e-57	198.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_654856_2	926556.Echvi_1408	2.16e-55	182.0	COG0338@1|root,COG0338@2|Bacteria,4NFZ2@976|Bacteroidetes,47N6K@768503|Cytophagia	976|Bacteroidetes	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k59_825413_1	631362.Thi970DRAFT_02450	5e-16	79.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWY7@135613|Chromatiales	135613|Chromatiales	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_825413_2	929558.SMGD1_0408	3.52e-70	234.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2YRCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_1275359_1	572480.Arnit_1103	2.17e-106	308.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2YMFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_766635_1	929558.SMGD1_0343	6.09e-16	77.4	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_766635_2	563040.Saut_1455	1.25e-25	105.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_31386_1	90814.KL370891_gene1439	1.74e-66	212.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1108 ABC-type Mn2 Zn2 transport systems permease components	yfeD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071944	-	ko:K09819,ko:K11606,ko:K11709	ko02010,map02010	M00243,M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	iEC042_1314.EC042_1518	ABC-3
k59_1162094_1	323850.Shew_1698	3.69e-60	206.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,2Q9E0@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1162095_1	1537917.JU82_06275	4.81e-37	140.0	COG4753@1|root,COG4753@2|Bacteria,1Q8YM@1224|Proteobacteria,42YGW@68525|delta/epsilon subdivisions,2YR37@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1616380_1	572480.Arnit_2485	4.58e-106	315.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_825437_1	983544.Lacal_1294	3.64e-38	129.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
k59_90085_1	1163398.AJJP01000050_gene1867	3.55e-72	233.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_90085_2	317025.Tcr_1380	6.02e-26	101.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,460G6@72273|Thiotrichales	72273|Thiotrichales	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
k59_1334044_1	497321.C664_15713	4.96e-71	237.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,dCache_1
k59_1334052_1	1172190.M947_01820	6.77e-89	269.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1RD7I@1224|Proteobacteria,42SM8@68525|delta/epsilon subdivisions,2YPEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_90102_1	497321.C664_08658	3.51e-31	110.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY2T@28216|Betaproteobacteria,2KXK6@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
k59_90102_2	62928.azo3933	7.39e-68	211.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,2KV1K@206389|Rhodocyclales	206389|Rhodocyclales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
k59_654908_1	313595.P700755_000282	2.03e-216	608.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1334065_1	1121875.KB907547_gene3138	1.07e-179	516.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1I09M@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_1334065_2	1121875.KB907547_gene3137	9.49e-77	229.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	fdx1	-	-	ko:K03522,ko:K05337	-	-	-	-	ko00000,ko04147	-	-	-	Fer4,Fer4_7
k59_1334065_3	1121875.KB907547_gene3136	0.0	993.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1HXEG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1275424_2	41431.PCC8801_2049	1.37e-13	72.0	COG0110@1|root,COG0110@2|Bacteria,1G35K@1117|Cyanobacteria,3KG06@43988|Cyanothece	1117|Cyanobacteria	S	Hexapeptide repeat of succinyl-transferase	act	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k59_1049228_1	1249480.B649_01930	2.58e-65	220.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_31448_1	225849.swp_3549	3.83e-67	211.0	COG2801@1|root,COG2801@2|Bacteria,1MVQ9@1224|Proteobacteria,1S5KN@1236|Gammaproteobacteria,2Q8UX@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Phage_terminase
k59_1727997_1	90814.KL370891_gene1891	4.09e-11	64.7	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1727997_2	1121105.ATXL01000014_gene1760	3.49e-11	68.6	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,4AZI3@81852|Enterococcaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k59_1559638_1	1408433.JHXV01000032_gene1130	4.11e-61	202.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_828075_1	563040.Saut_1766	4.88e-83	253.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2YP2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_599299_1	90814.KL370891_gene639	8.88e-178	523.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,45ZRH@72273|Thiotrichales	72273|Thiotrichales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_148032_1	411154.GFO_1539	3.41e-60	198.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
k59_148032_2	1121931.AUHG01000012_gene2630	2.08e-13	68.6	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
k59_1619106_1	1042375.AFPL01000035_gene2835	5.11e-14	76.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RP76@1236|Gammaproteobacteria,4666Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,PilJ
k59_882893_1	1172190.M947_02430	6e-65	212.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42MPN@68525|delta/epsilon subdivisions,2YMHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar basal body protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_148039_1	392500.Swoo_3132	2.17e-90	275.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,2QA1Y@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltC	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iG2583_1286.G2583_3622,iUMNK88_1353.UMNK88_3661	DUF3393,SLT
k59_1336788_1	1121931.AUHG01000010_gene756	4.06e-100	313.0	COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,1HXUZ@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1619153_1	572480.Arnit_1795	9.45e-97	310.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_1336828_1	70448.Q0P3F1	1.63e-106	322.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,34JUG@3041|Chlorophyta	3041|Chlorophyta	C	Cytochrome C and Quinol oxidase polypeptide I	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_488248_1	411154.GFO_2175	8.13e-90	274.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-lyase	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_488266_1	215803.DB30_2150	8.34e-17	80.9	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,43E8F@68525|delta/epsilon subdivisions,2WZZP@28221|Deltaproteobacteria,2Z1JY@29|Myxococcales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_769350_1	1121859.KB890743_gene58	2.48e-35	133.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_769350_2	1286632.P278_11970	5.28e-67	219.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,1HZG8@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1390419_1	1328313.DS2_00015	2.21e-68	226.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,4661S@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_882986_1	929558.SMGD1_0406	5.95e-31	117.0	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,42PR6@68525|delta/epsilon subdivisions,2YNJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyltransferase	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
k59_882986_2	326298.Suden_1939	8.16e-24	95.9	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YP5K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	protein-glutamate methylesterase	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
k59_1505477_1	983544.Lacal_0129	7.25e-234	672.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
k59_431432_1	391598.FBBAL38_05710	6.27e-50	180.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_716512_1	929558.SMGD1_2396	1.8e-106	318.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_262849_1	563040.Saut_2097	1.26e-114	339.0	COG3245@1|root,COG3258@1|root,COG3245@2|Bacteria,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,42WAQ@68525|delta/epsilon subdivisions,2YTG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_1559788_1	504487.JCM19302_1490	3.88e-98	300.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1HZ2W@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1559788_2	1137281.D778_02005	3.58e-29	111.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1HYEZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_716525_1	1469557.JSWF01000028_gene2990	1.81e-65	219.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia	976|Bacteroidetes	P	COG0659 Sulfate permease and related	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
k59_657753_1	945713.IALB_2200	6.44e-53	181.0	COG0206@1|root,COG0206@2|Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1164923_1	572480.Arnit_2582	2e-125	372.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_318750_1	1123517.JOMR01000001_gene1311	3.3e-171	497.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,45ZVA@72273|Thiotrichales	72273|Thiotrichales	GM	Polysaccharide biosynthesis protein	wbtA	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_92930_1	1123326.JFBL01000007_gene633	1.14e-77	243.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42RY6@68525|delta/epsilon subdivisions,2YPET@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_205877_1	317025.Tcr_1449	3.49e-68	230.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,460Z0@72273|Thiotrichales	72273|Thiotrichales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_205877_2	317025.Tcr_1448	1.88e-69	213.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,4614E@72273|Thiotrichales	72273|Thiotrichales	N	flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_205877_4	1168067.JAGP01000001_gene1316	3.74e-31	118.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,460CQ@72273|Thiotrichales	72273|Thiotrichales	T	Sigma-54 interaction domain	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
k59_1278164_1	226185.EF_3255	2.05e-16	83.6	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,4B0IS@81852|Enterococcaceae	91061|Bacilli	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_148173_1	1249480.B649_04540	1.88e-57	181.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,42WM3@68525|delta/epsilon subdivisions,2YRZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
k59_1278165_1	1244869.H261_15452	1.18e-100	319.0	COG0664@1|root,COG1235@1|root,COG2703@1|root,COG0664@2|Bacteria,COG1235@2|Bacteria,COG2703@2|Bacteria,1R90N@1224|Proteobacteria,2TTTI@28211|Alphaproteobacteria,2JVDD@204441|Rhodospirillales	204441|Rhodospirillales	PT	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B_2,cNMP_binding
k59_318774_1	929558.SMGD1_2788	1.22e-26	110.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_318774_2	929558.SMGD1_2789	4.22e-95	288.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2YN4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0283	DHQ_synthase
k59_318790_1	411154.GFO_2533	6.82e-117	338.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1HYTE@117743|Flavobacteriia	976|Bacteroidetes	P	COG0569 K transport systems NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_1787860_1	243275.TDE_2498	2.27e-22	93.6	COG0426@1|root,COG0426@2|Bacteria,2J57P@203691|Spirochaetes	203691|Spirochaetes	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Lactamase_B,Response_reg
k59_1787860_2	697282.Mettu_1505	2.96e-24	102.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria,1XGA9@135618|Methylococcales	135618|Methylococcales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_1787860_3	1485544.JQKP01000010_gene791	3.46e-22	92.8	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria,2VP4Q@28216|Betaproteobacteria,44VB1@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_560774_3	1453505.JASY01000037_gene3909	1.15e-80	244.0	COG1595@1|root,COG1595@2|Bacteria,4NSV9@976|Bacteroidetes,1I4SV@117743|Flavobacteriia,2NWEI@237|Flavobacterium	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
k59_560774_4	926559.JoomaDRAFT_1231	2.98e-99	299.0	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes,1HXAM@117743|Flavobacteriia	976|Bacteroidetes	K	Pfam Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k59_1069062_1	929558.SMGD1_2308	3.22e-52	176.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1009741_1	563040.Saut_0281	6.81e-54	178.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
k59_1296876_1	926562.Oweho_1468	2.7e-32	114.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia,2PB1G@246874|Cryomorphaceae	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
k59_1296876_2	867900.Celly_0234	2.67e-42	150.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia,1F8Q2@104264|Cellulophaga	976|Bacteroidetes	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_788571_1	62928.azo0916	2.31e-66	216.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,2KW1P@206389|Rhodocyclales	206389|Rhodocyclales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k59_1631492_1	1123514.KB905899_gene1105	4.28e-61	195.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,460Z1@72273|Thiotrichales	72273|Thiotrichales	S	YaeQ	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_1183611_1	1333507.AUTQ01000274_gene4046	2.61e-32	122.0	COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,1S589@1236|Gammaproteobacteria,2Q37E@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	Q	2-keto-4-pentenoate hydratase	-	-	4.2.1.80	ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04781	RC00750,RC01213	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
k59_953062_1	504487.JCM19302_2497	1.5e-71	224.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HWQR@117743|Flavobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_953062_2	504487.JCM19302_2495	1.14e-203	571.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1HWYT@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_278312_1	1565129.JSFF01000003_gene2115	1.51e-103	314.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,2Q9VP@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM Peptidoglycan-binding LysM	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_506500_1	326298.Suden_1068	9.42e-83	256.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_337544_1	1380600.AUYN01000010_gene892	6.04e-125	378.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_449230_1	1380600.AUYN01000006_gene295	7.7e-104	322.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_449230_2	504487.JCM19302_222	7.29e-37	133.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1HX7A@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_278329_1	983544.Lacal_2525	4.69e-78	245.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1HYAK@117743|Flavobacteriia	976|Bacteroidetes	J	(SAM)-dependent	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1750011_1	411154.GFO_1959	3.04e-143	426.0	COG4251@1|root,COG4251@2|Bacteria,4NDUQ@976|Bacteroidetes,1HZ8B@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
k59_1633336_1	317025.Tcr_1086	8.98e-17	73.6	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,4616D@72273|Thiotrichales	72273|Thiotrichales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_1633336_2	90814.KL370891_gene948	2.07e-52	176.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,45ZZ7@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_903628_1	319236.JCM19294_827	1.63e-26	103.0	COG0428@1|root,COG0428@2|Bacteria,4PJ79@976|Bacteroidetes,1IC3B@117743|Flavobacteriia,3HMAE@363408|Nonlabens	976|Bacteroidetes	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
k59_903628_2	411154.GFO_1583	2.03e-71	219.0	2BI62@1|root,32CBB@2|Bacteria,4NQGF@976|Bacteroidetes,1I3F8@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
k59_168699_1	869213.JCM21142_93989	8.34e-72	231.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,47NKF@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1633341_1	313598.MED152_08920	3.66e-21	89.4	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1HXMG@117743|Flavobacteriia,3VVSC@52959|Polaribacter	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1633341_2	1178825.ALIH01000003_gene2106	2.93e-51	164.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
k59_1633341_3	1121007.AUML01000005_gene2213	0.00019	42.7	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia,2YIEI@290174|Aquimarina	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
k59_1012883_1	1121012.AUKX01000042_gene2493	1.69e-08	54.3	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia,23GZI@178469|Arenibacter	976|Bacteroidetes	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
k59_1012883_2	1380600.AUYN01000001_gene2409	2.09e-121	354.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1HWK6@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_846038_1	1144313.PMI10_04217	1.45e-69	216.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1I2EF@117743|Flavobacteriia,2NUBD@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_846038_2	983544.Lacal_0362	2.61e-45	160.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_1580462_1	572480.Arnit_1617	3.9e-157	468.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	nrfI	GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_619535_1	572480.Arnit_1965	3.61e-57	180.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2YP4R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_619535_2	572480.Arnit_1966	1.34e-113	328.0	COG0125@1|root,COG0125@2|Bacteria,1R98D@1224|Proteobacteria,43B5Z@68525|delta/epsilon subdivisions,2YP5N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_619535_3	572480.Arnit_1967	2.98e-212	591.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2YMII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_903674_1	717772.THIAE_01875	6.1e-29	119.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RSD8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_846086_1	323850.Shew_1090	2.24e-92	278.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria,2Q9YA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,OmpA_membrane,TSP_3
k59_1071614_1	313595.P700755_003775	9.96e-43	155.0	COG1228@1|root,COG1228@2|Bacteria,4PHV7@976|Bacteroidetes,1IGPI@117743|Flavobacteriia,4C4H5@83612|Psychroflexus	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_168770_1	1565129.JSFF01000022_gene1415	3.87e-07	50.4	COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,2Q90J@267890|Shewanellaceae	1236|Gammaproteobacteria	H	PFAM ATP-NAD AcoX kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
k59_168770_2	323850.Shew_2413	2.31e-37	127.0	2CJ8F@1|root,32D8I@2|Bacteria,1QSA5@1224|Proteobacteria,1T7D1@1236|Gammaproteobacteria,2QCX9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	YfcL protein	-	-	-	-	-	-	-	-	-	-	-	-	YfcL
k59_168770_3	425104.Ssed_1642	5.55e-09	55.1	COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,1S48A@1236|Gammaproteobacteria,2QAHH@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM tRNA rRNA methyltransferase (SpoU)	IV02_28330	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_1012959_1	867900.Celly_1276	2.28e-38	147.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia,1F8MR@104264|Cellulophaga	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_619625_2	929558.SMGD1_1180	2.67e-13	67.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K04739,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko04910,ko05111,map02020,map02024,map02025,map02026,map04910,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
k59_903762_1	1123518.ARWI01000001_gene679	6.65e-27	101.0	2D5Q1@1|root,32TJK@2|Bacteria,1N688@1224|Proteobacteria,1SS8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_903762_2	1123518.ARWI01000001_gene678	5.39e-54	174.0	COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,1S7XG@1236|Gammaproteobacteria,461E2@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
k59_1012998_1	929558.SMGD1_0627	2.64e-43	155.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1012998_2	351348.Maqu_1806	1.16e-16	81.3	COG0517@1|root,COG2905@1|root,COG5001@1|root,COG0517@2|Bacteria,COG2905@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465FS@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_619634_1	572480.Arnit_3103	2.95e-64	204.0	COG2307@1|root,COG2307@2|Bacteria,1NMSC@1224|Proteobacteria,42V9T@68525|delta/epsilon subdivisions,2YQAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_619634_2	367737.Abu_2307	2.15e-61	201.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2YNA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_955293_1	558152.IQ37_08560	7.66e-16	83.6	COG4907@1|root,COG4907@2|Bacteria,4NJKC@976|Bacteroidetes,1I111@117743|Flavobacteriia,3ZQDJ@59732|Chryseobacterium	976|Bacteroidetes	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_1232291_1	749222.Nitsa_1068	3.8e-44	164.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1232291_2	1123399.AQVE01000001_gene698	3.02e-06	52.4	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1SM26@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1232291_3	696747.NIES39_L05760	2.78e-06	51.6	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2203@1|root,COG3322@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3322@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1013007_1	1278309.KB907099_gene3146	3.09e-22	94.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XIFG@135619|Oceanospirillales	135619|Oceanospirillales	E	in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1013007_2	1278309.KB907099_gene3145	8.15e-38	128.0	2CU16@1|root,32SUH@2|Bacteria,1N3T8@1224|Proteobacteria,1SBCZ@1236|Gammaproteobacteria,1XKTF@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1071664_1	1353276.JADR01000001_gene290	2.71e-82	252.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1HX64@117743|Flavobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_619658_1	1392488.JHZY01000002_gene818	2.67e-99	311.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,1HWZE@117743|Flavobacteriia,2XJVP@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	ybaL_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
k59_1580592_1	1121937.AUHJ01000032_gene3071	7.4e-24	93.2	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,46787@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_1580592_2	1123228.AUIH01000024_gene3259	1.15e-63	216.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XHCD@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1232311_1	504487.JCM19302_243	1.22e-62	211.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_1409204_1	563040.Saut_1067	4.8e-85	269.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,42YDE@68525|delta/epsilon subdivisions,2YR8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS
k59_1580603_1	572480.Arnit_0596	2.14e-60	192.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,42RN3@68525|delta/epsilon subdivisions,2YPXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	abc transporter atp-binding protein	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_1580603_2	572480.Arnit_0595	1.17e-36	132.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42RAU@68525|delta/epsilon subdivisions,2YPYM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1409211_1	326298.Suden_0571	2.13e-167	483.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria,1MUGA@1224|Proteobacteria,42NI0@68525|delta/epsilon subdivisions,2YNKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP citrate synthase	-	-	2.3.3.8	ko:K15230	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,Ligase_CoA
k59_1071706_1	1123518.ARWI01000001_gene2402	1.96e-16	77.8	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,45ZU3@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_1071706_2	1123514.KB905899_gene1148	5.7e-226	632.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,46024@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_1071706_3	1123514.KB905899_gene1147	6.47e-20	87.4	COG1340@1|root,COG1340@2|Bacteria,1QVWN@1224|Proteobacteria,1T2KY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
k59_1232377_1	1249480.B649_01930	2.01e-96	300.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_563914_1	616991.JPOO01000003_gene580	4.36e-49	177.0	COG1073@1|root,COG1073@2|Bacteria,4NID3@976|Bacteroidetes,1I78I@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
k59_168974_1	1121935.AQXX01000132_gene2659	4.39e-22	95.9	COG3608@1|root,COG3608@2|Bacteria,1N396@1224|Proteobacteria,1RMKN@1236|Gammaproteobacteria,1XJNQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1633545_1	504487.JCM19302_809	2.16e-94	292.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_1409317_1	504487.JCM19302_1433	1.72e-08	53.9	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1I0I9@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1409317_2	983544.Lacal_0726	8.2e-62	198.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_619822_1	1123037.AUDE01000008_gene619	3.03e-70	216.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1HXWH@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k59_619822_3	1046627.BZARG_2990	2.28e-61	197.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_1633559_1	326298.Suden_1604	2.36e-149	432.0	COG1776@1|root,COG1776@2|Bacteria,1RICK@1224|Proteobacteria,42NMU@68525|delta/epsilon subdivisions,2YMV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_1633559_2	326298.Suden_1605	2.57e-137	390.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2YMP8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1386	Ribul_P_3_epim
k59_564006_1	269798.CHU_2664	6.32e-13	65.5	COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_564006_2	1237149.C900_02202	2.52e-47	155.0	COG2050@1|root,COG2050@2|Bacteria,4NT7R@976|Bacteroidetes,47RY0@768503|Cytophagia	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1071797_1	1117958.PE143B_0129245	6e-70	225.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage terminase, large subunit	Z012_12305	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_280682_1	886377.Murru_0954	3.44e-43	162.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
k59_846409_1	1484460.JSWG01000010_gene3193	4.08e-22	91.7	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_846409_3	1137281.D778_02212	5.46e-122	355.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_846409_4	1178825.ALIH01000002_gene898	1.58e-61	192.0	COG0517@1|root,COG0517@2|Bacteria,4NZCM@976|Bacteroidetes,1I9F3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_846409_5	1178825.ALIH01000002_gene897	9.64e-55	174.0	2F97K@1|root,341IZ@2|Bacteria,4P44R@976|Bacteroidetes,1I9JY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_846409_6	1178825.ALIH01000002_gene896	7.32e-75	239.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_564047_1	1450525.JATV01000006_gene885	3.78e-114	357.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2NSTD@237|Flavobacterium	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1232560_1	572480.Arnit_2260	2.82e-140	406.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2YN7C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_1232562_1	1123517.JOMR01000001_gene1317	8.23e-105	311.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	wecB	-	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_1232562_2	76869.PputGB1_1374	5.76e-22	92.8	COG0451@1|root,COG1898@1|root,COG0451@2|Bacteria,COG1898@2|Bacteria,1MXGB@1224|Proteobacteria,1RSK7@1236|Gammaproteobacteria,1YXFK@136845|Pseudomonas putida group	1236|Gammaproteobacteria	GM	Polysaccharide biosynthesis protein	fnlB	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_619927_1	1121931.AUHG01000019_gene3017	6.11e-81	258.0	COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia	976|Bacteroidetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
k59_619927_2	1121931.AUHG01000019_gene3016	1.58e-13	69.7	COG3281@1|root,COG3281@2|Bacteria,4PMAP@976|Bacteroidetes,1HZME@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH
k59_1409427_1	1172190.M947_02905	1.5e-35	134.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_1409427_2	709032.Sulku_1914	1.77e-11	64.7	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2YPMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_179910_1	1380600.AUYN01000009_gene1189	5.49e-105	324.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_462347_1	497321.C664_19630	6.06e-40	135.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,2KWIS@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_462347_2	305700.B447_19899	4.99e-45	150.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,2KWAG@206389|Rhodocyclales	206389|Rhodocyclales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_801149_1	1166018.FAES_0273	4.24e-80	265.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KCF@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_9653_1	913325.N799_02795	4.8e-11	62.8	2CBKC@1|root,32RTJ@2|Bacteria,1N5I0@1224|Proteobacteria,1SACI@1236|Gammaproteobacteria,1X74V@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9653_2	1137281.D778_00401	5.76e-184	533.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1HYTZ@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1648292_1	143224.JQMD01000002_gene4170	0.0	1372.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1648292_2	1341155.FSS13T_10800	1.08e-46	164.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia,2NTDK@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1194542_1	1209072.ALBT01000003_gene709	7.26e-98	297.0	COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,1RPD1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA methylase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_11200_1	1380600.AUYN01000009_gene1126	3.75e-230	640.0	COG3876@1|root,COG3876@2|Bacteria,4NKHR@976|Bacteroidetes,1HZYR@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_11200_2	1380600.AUYN01000009_gene1125	4.98e-294	810.0	COG0521@1|root,COG0521@2|Bacteria,4PKAT@976|Bacteroidetes,1IKAW@117743|Flavobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
k59_1083948_1	1121912.AUHD01000001_gene2480	6.34e-124	373.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_1366342_1	929558.SMGD1_0462	9.92e-27	104.0	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1366342_2	563040.Saut_1484	1.3e-71	226.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_349913_1	411154.GFO_0098	1.91e-122	374.0	COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,1HXUZ@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1480258_1	143224.JQMD01000002_gene3103	2.41e-14	74.7	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_858481_1	1121007.AUML01000023_gene1185	8.92e-75	233.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,1HWT1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0798 Arsenite efflux pump ACR3 and related	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_858481_2	1492737.FEM08_14430	5.25e-101	298.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,1HYIW@117743|Flavobacteriia,2NSBT@237|Flavobacterium	976|Bacteroidetes	T	Protein tyrosine phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1140649_1	563040.Saut_0901	6.06e-110	322.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2YMHA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1253834_1	391603.FBALC1_01927	5.46e-93	277.0	COG4638@1|root,COG4638@2|Bacteria,4NJ33@976|Bacteroidetes,1HZFM@117743|Flavobacteriia	976|Bacteroidetes	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k59_124317_1	1123037.AUDE01000027_gene2115	3.59e-38	142.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia	976|Bacteroidetes	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_1536104_1	1121931.AUHG01000016_gene1107	1.65e-128	375.0	COG0457@1|root,COG0457@2|Bacteria,4NGMH@976|Bacteroidetes,1HZM6@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
k59_1194571_1	313603.FB2170_14813	2.06e-138	409.0	COG0484@1|root,COG0484@2|Bacteria,4P0AH@976|Bacteroidetes	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_294132_1	411154.GFO_0426	2.95e-121	362.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_238201_1	929558.SMGD1_2002	2.86e-77	256.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
k59_1706378_1	1380600.AUYN01000007_gene3241	1.37e-187	548.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1593913_1	748247.AZKH_2764	3.79e-21	94.4	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,2KVTT@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_1649975_1	1168067.JAGP01000001_gene1923	2.27e-99	292.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria,1SQK7@1236|Gammaproteobacteria,4632R@72273|Thiotrichales	72273|Thiotrichales	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	-
k59_1649975_2	1168067.JAGP01000001_gene1922	1.31e-125	365.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,460QA@72273|Thiotrichales	72273|Thiotrichales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_294139_1	1123518.ARWI01000001_gene1771	1.15e-75	232.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,460D0@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_181654_1	929558.SMGD1_2575	3.14e-262	751.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_294140_1	411154.GFO_3471	1.68e-06	48.5	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_294140_2	411154.GFO_3472	6.37e-146	422.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,1HYIN@117743|Flavobacteriia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1480309_1	1123514.KB905899_gene520	1.37e-68	211.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,460W3@72273|Thiotrichales	72273|Thiotrichales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
k59_407240_1	1121931.AUHG01000010_gene552	7.7e-103	312.0	COG1793@1|root,COG1793@2|Bacteria,4NEKP@976|Bacteroidetes,1HXWE@117743|Flavobacteriia	976|Bacteroidetes	L	Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
k59_407240_2	1121931.AUHG01000010_gene551	1.52e-43	150.0	COG1236@1|root,COG1236@2|Bacteria,4NFN7@976|Bacteroidetes,1HZJP@117743|Flavobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
k59_407243_1	1380600.AUYN01000009_gene1981	4.39e-187	550.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
k59_1706427_1	1121931.AUHG01000015_gene1206	4.91e-109	317.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I20T@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
k59_1084025_1	1123514.KB905899_gene1021	6.16e-44	152.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,45ZSU@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1084025_2	1123518.ARWI01000001_gene221	0.0	1506.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_238255_1	1123518.ARWI01000001_gene298	6.41e-60	185.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,1SCCK@1236|Gammaproteobacteria,4615W@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_238255_2	317025.Tcr_1118	2.91e-40	146.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,45ZPK@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1536166_1	243233.MCA0547	1.41e-43	162.0	COG2461@1|root,COG5001@1|root,COG2461@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XE5X@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS_9
k59_1140723_1	1123514.KB905899_gene1123	1.44e-31	119.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,4609B@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_1140723_2	1123518.ARWI01000001_gene419	1.64e-79	236.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,46112@72273|Thiotrichales	72273|Thiotrichales	H	queuosine biosynthesis protein QueD	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_1140723_3	1123518.ARWI01000001_gene2430	8.68e-40	139.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,460AW@72273|Thiotrichales	72273|Thiotrichales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_1311582_1	1121931.AUHG01000011_gene2231	2.67e-89	286.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_802917_1	1123518.ARWI01000001_gene1311	4.19e-163	460.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,460DH@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_802917_2	1123518.ARWI01000001_gene1310	3.08e-43	158.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,45ZW5@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_1253913_1	1007105.PT7_0523	1.33e-111	338.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria,3T2DB@506|Alcaligenaceae	28216|Betaproteobacteria	U	the major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_181726_1	1408473.JHXO01000015_gene1917	2.99e-199	572.0	COG3537@1|root,COG3537@2|Bacteria,4NIAX@976|Bacteroidetes,2FQH5@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	GDPD,Glyco_hydro_92
k59_633335_1	98439.AJLL01000067_gene1568	1.67e-49	165.0	COG1926@1|root,COG1926@2|Bacteria,1G2IS@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_690351_1	1469557.JSWF01000017_gene2306	7.76e-43	142.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_690351_2	983544.Lacal_2791	6.15e-55	189.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_519842_1	411154.GFO_2757	1.26e-90	278.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HY7E@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k59_464187_1	1408473.JHXO01000013_gene610	2.75e-124	377.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,2FMQN@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4
k59_464187_2	1380600.AUYN01000009_gene1389	8.67e-57	180.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,1I20G@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
k59_1253941_1	1123518.ARWI01000001_gene45	1.23e-97	291.0	COG0834@1|root,COG0834@2|Bacteria,1RI5R@1224|Proteobacteria,1S5PV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_576780_1	1168034.FH5T_15055	1.36e-174	496.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,2FMCX@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_68565_1	556267.HWAG_00867	9.03e-23	95.9	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_68565_2	326298.Suden_1599	2.73e-59	198.0	2FGCU@1|root,34890@2|Bacteria,1P1W4@1224|Proteobacteria,42VMW@68525|delta/epsilon subdivisions,2YSCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_690374_1	90814.KL370891_gene1659	7.44e-206	602.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1140775_1	411154.GFO_2725	3.97e-24	95.5	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1I2EY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1140775_2	411154.GFO_2726	8.91e-118	345.0	28IMZ@1|root,2Z8NF@2|Bacteria,4NIZ8@976|Bacteroidetes,1I0D0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1366493_1	1348657.M622_09965	1.75e-64	218.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,2KVTG@206389|Rhodocyclales	206389|Rhodocyclales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_690386_1	563040.Saut_1689	3.21e-36	131.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2YMEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_690386_2	929558.SMGD1_1884	6.32e-87	263.0	2AIM2@1|root,302EJ@2|Bacteria,1Q99E@1224|Proteobacteria,42ZJ9@68525|delta/epsilon subdivisions,2YRN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1594055_1	509635.N824_08835	1.43e-219	648.0	COG3408@1|root,COG3408@2|Bacteria,4NHZ6@976|Bacteroidetes,1IVE3@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
k59_1594055_2	208444.JNYY01000001_gene5271	7.82e-05	44.7	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DZS9@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
k59_1366520_1	1380600.AUYN01000009_gene967	1.73e-207	635.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_68609_1	1336233.JAEH01000042_gene3894	2.92e-66	212.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,2Q94M@267890|Shewanellaceae	1236|Gammaproteobacteria	H	PFAM aminotransferase class-III	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
k59_519907_1	1121931.AUHG01000010_gene750	1.26e-127	366.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1366525_1	709032.Sulku_1316	1.19e-144	417.0	COG0426@1|root,COG0426@2|Bacteria,1NDXY@1224|Proteobacteria,42N11@68525|delta/epsilon subdivisions,2YNA0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
k59_1194691_2	326298.Suden_0847	2.34e-71	223.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_803021_1	1443665.JACA01000001_gene2593	3.21e-50	162.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia,2YHDT@290174|Aquimarina	976|Bacteroidetes	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_803021_2	1380600.AUYN01000001_gene2408	1.25e-180	506.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
k59_464246_1	90814.KL370891_gene1836	6.51e-158	457.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,460MD@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_464246_2	1123518.ARWI01000001_gene1802	8.26e-42	149.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,46029@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_11409_1	1121887.AUDK01000032_gene1019	1.87e-135	403.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia,2NSSU@237|Flavobacterium	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1480494_1	1178825.ALIH01000005_gene340	2.27e-37	136.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_576874_2	744979.R2A130_0076	3.82e-21	94.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_576874_3	860228.Ccan_04560	0.000118	45.4	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1I20H@117743|Flavobacteriia,1ERWJ@1016|Capnocytophaga	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_1028787_1	1195246.AGRI_15861	5.72e-59	209.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,466BR@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,HAMP,PAS_3,PAS_9,dCache_1
k59_464282_1	90814.KL370891_gene1262	1.15e-67	213.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,460KX@72273|Thiotrichales	72273|Thiotrichales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k59_464282_2	1123518.ARWI01000001_gene2467	5.59e-85	262.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,4617B@72273|Thiotrichales	72273|Thiotrichales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_915341_1	1122225.AULQ01000002_gene801	1.72e-95	305.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HZFE@117743|Flavobacteriia	976|Bacteroidetes	T	7TMR-DISM extracellular 2	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
k59_915341_2	1380600.AUYN01000007_gene3244	6.74e-137	394.0	COG0589@1|root,COG0589@2|Bacteria,4NIWH@976|Bacteroidetes,1HXPX@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_424885_2	563040.Saut_0699	2.95e-77	233.0	COG1214@1|root,COG1214@2|Bacteria,1Q1J6@1224|Proteobacteria,42TUF@68525|delta/epsilon subdivisions,2YQ3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_821405_1	572480.Arnit_0112	1.03e-75	234.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	acuI	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_821405_2	572480.Arnit_0111	2.47e-16	77.8	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,MASE2,PAS_7
k59_1553363_1	1111732.AZOD01000009_gene1188	5.14e-12	70.1	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1X52Y@135614|Xanthomonadales	135614|Xanthomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_1498731_1	90814.KL370891_gene1846	1.48e-120	347.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,460FX@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_1498731_2	1123518.ARWI01000001_gene1792	1.38e-166	468.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_28092_1	1123514.KB905899_gene649	2.13e-48	161.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,45ZUU@72273|Thiotrichales	72273|Thiotrichales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_28092_2	90814.KL370891_gene1426	5.55e-103	303.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,460NN@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_28092_3	1123518.ARWI01000001_gene2239	4.5e-21	90.5	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1206929_1	1509405.GV67_04115	6.67e-20	89.4	28H75@1|root,2Z7JG@2|Bacteria,1MU3Y@1224|Proteobacteria,2TVB5@28211|Alphaproteobacteria,4BGWP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
k59_709658_1	1123517.JOMR01000001_gene768	4.26e-136	398.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RWCC@1236|Gammaproteobacteria,460AQ@72273|Thiotrichales	72273|Thiotrichales	M	UDP-N-acetylglucosamine 2-epimerase	-	-	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_199543_1	929558.SMGD1_0842	1.39e-96	288.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2YMXU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_199543_2	563040.Saut_0353	6.34e-29	111.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2YMV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_1724298_1	572480.Arnit_1344	5.84e-07	49.3	COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,42V0Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Putative thioesterase (yiiD_Cterm)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
k59_1724298_2	572480.Arnit_1345	8.22e-69	228.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2YR4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Hydrolase_4
k59_762992_1	768670.Calni_1166	2.51e-20	89.7	COG0451@1|root,COG0451@2|Bacteria,2GFXM@200930|Deferribacteres	200930|Deferribacteres	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_762992_2	1046627.BZARG_1633	8.21e-245	687.0	COG0119@1|root,COG0119@2|Bacteria,4NHR2@976|Bacteroidetes,1HZQE@117743|Flavobacteriia	976|Bacteroidetes	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
k59_762992_3	1250005.PHEL85_1416	1.42e-106	315.0	COG1212@1|root,COG1212@2|Bacteria,4NKB4@976|Bacteroidetes,1I2KE@117743|Flavobacteriia,3VX0U@52959|Polaribacter	976|Bacteroidetes	H	Cytidylyltransferase	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_762992_4	313598.MED152_05625	4.85e-32	117.0	COG0546@1|root,COG0546@2|Bacteria,4NN2C@976|Bacteroidetes,1I1WE@117743|Flavobacteriia,3VX7F@52959|Polaribacter	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1498765_1	572480.Arnit_0529	0.000126	43.1	COG2966@1|root,COG2966@2|Bacteria,1NH2X@1224|Proteobacteria,42QZR@68525|delta/epsilon subdivisions,2YP1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
k59_1498765_2	572480.Arnit_0543	2.01e-47	154.0	2BQJ4@1|root,32JEZ@2|Bacteria,1Q29Y@1224|Proteobacteria,42V8X@68525|delta/epsilon subdivisions,2YQIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1498765_3	572480.Arnit_0544	1.47e-32	118.0	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_424921_1	742741.HMPREF9475_04039	7.76e-08	55.1	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,21Z1T@1506553|Lachnoclostridium	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_424921_2	944479.JQLX01000010_gene540	5.17e-09	60.8	COG3206@1|root,COG3206@2|Bacteria,1PGV5@1224|Proteobacteria,43A94@68525|delta/epsilon subdivisions,2X598@28221|Deltaproteobacteria,2M7HV@213113|Desulfurellales	28221|Deltaproteobacteria	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_762995_1	572480.Arnit_0817	1.5e-103	330.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1498768_1	411154.GFO_1532	5.79e-158	446.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1HXVM@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_199561_1	1232410.KI421413_gene534	1.13e-73	241.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZD5@68525|delta/epsilon subdivisions,2WUEK@28221|Deltaproteobacteria,43TFW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, HAMP and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,sCache_3_2
k59_1440678_1	1120953.AUBH01000004_gene3182	2.34e-38	146.0	COG2199@1|root,COG3706@2|Bacteria,1R0U8@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1781650_1	326298.Suden_0536	2.17e-129	398.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1498788_1	506534.Rhein_2077	1.2e-10	61.6	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1WX51@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1498788_2	1123518.ARWI01000001_gene559	1.74e-55	179.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,461EX@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_1498788_3	1335757.SPICUR_04615	1.52e-08	51.2	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_312131_1	745718.JADT01000013_gene1350	9.17e-62	202.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_312131_2	1178825.ALIH01000007_gene1661	1.51e-104	305.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,1HZAW@117743|Flavobacteriia	976|Bacteroidetes	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_1553435_1	1168289.AJKI01000051_gene829	7.63e-56	178.0	COG0454@1|root,COG0456@2|Bacteria,4NQ9E@976|Bacteroidetes,2FY34@200643|Bacteroidia,3XKQN@558415|Marinilabiliaceae	976|Bacteroidetes	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
k59_1612707_1	62928.azo0917	3.71e-98	288.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VK0C@28216|Betaproteobacteria,2KW5Q@206389|Rhodocyclales	206389|Rhodocyclales	K	response regulator	dctR	-	-	ko:K11712	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	GerE,Response_reg
k59_141713_1	1406840.Q763_09710	1.78e-83	249.0	2EMQR@1|root,33FD8@2|Bacteria,4NY1K@976|Bacteroidetes,1I8UT@117743|Flavobacteriia,2NX42@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141713_2	655815.ZPR_3452	1.67e-108	314.0	2E2HG@1|root,32XME@2|Bacteria,4NU25@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141713_3	1406840.Q763_09700	4.47e-276	756.0	2E8Z7@1|root,34AH2@2|Bacteria,4P5J4@976|Bacteroidetes,1I86W@117743|Flavobacteriia,2NT9C@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_424958_1	1380600.AUYN01000006_gene306	6.75e-47	164.0	COG1577@1|root,COG2827@1|root,COG1577@2|Bacteria,COG2827@2|Bacteria,4NEXC@976|Bacteroidetes,1HY6C@117743|Flavobacteriia	976|Bacteroidetes	I	GHMP Kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_424958_2	1380600.AUYN01000006_gene305	5.38e-137	399.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
k59_1383840_1	1123514.KB905899_gene2035	8.22e-135	405.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,45ZW5@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_1498816_1	317025.Tcr_1446	1.89e-159	456.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,460CQ@72273|Thiotrichales	72273|Thiotrichales	T	Sigma-54 interaction domain	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
k59_1498816_2	1123514.KB905899_gene1440	3.03e-40	144.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,460K3@72273|Thiotrichales	72273|Thiotrichales	T	PAS domain	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k59_1440729_1	929558.SMGD1_1015	2.93e-116	343.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2YMQ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_1440729_2	326298.Suden_0210	3.86e-09	54.3	2EHAZ@1|root,33B2U@2|Bacteria,1PA3S@1224|Proteobacteria,42X9M@68525|delta/epsilon subdivisions,2YQVA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_367508_1	411154.GFO_1903	1.21e-160	456.0	COG3569@1|root,COG3569@2|Bacteria,4NGTF@976|Bacteroidetes,1HYFX@117743|Flavobacteriia	976|Bacteroidetes	L	DNA topoisomerase I	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
k59_256733_1	929558.SMGD1_1329	9.39e-62	205.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_367529_1	411154.GFO_2764	3.55e-101	312.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_876712_1	1121931.AUHG01000010_gene221	5.2e-134	382.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_482159_1	1123514.KB905899_gene1248	4.81e-210	600.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,4607H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_1440779_1	1380600.AUYN01000009_gene1637	2.55e-93	285.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_594007_1	929558.SMGD1_2083	3.6e-38	143.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1667940_1	313603.FB2170_07949	2.47e-217	603.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
k59_1667940_2	1121875.KB907547_gene3144	3.04e-133	386.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1HY4Q@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_932357_1	1392490.JHZX01000001_gene123	8.38e-112	354.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k59_1330218_1	572480.Arnit_0391	9.44e-101	320.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2YMBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
k59_482188_1	1056820.KB900700_gene1125	4.78e-14	72.8	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,2PNIG@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_482188_2	543632.JOJL01000014_gene9251	1.35e-05	49.3	COG0500@1|root,COG0500@2|Bacteria,2I3YC@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_1158334_1	305700.B447_00625	5.25e-91	267.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,2VQ50@28216|Betaproteobacteria,2KW5Y@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	norC	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
k59_1158334_2	1123367.C666_03760	0.000182	42.7	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,2KUBH@206389|Rhodocyclales	206389|Rhodocyclales	C	to the heme-copper respiratory oxidase family	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
k59_425066_1	1415778.JQMM01000001_gene1974	1.3e-89	265.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1J654@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_1781786_1	1442598.JABW01000003_gene93	5.77e-51	168.0	COG1216@1|root,COG1216@2|Bacteria,1N8UX@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF616
k59_86623_1	1123518.ARWI01000001_gene983	8.88e-20	87.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,45ZS4@72273|Thiotrichales	72273|Thiotrichales	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_86623_2	1123518.ARWI01000001_gene984	3.02e-97	290.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales	72273|Thiotrichales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_763143_1	1123518.ARWI01000001_gene1938	5.32e-45	155.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,460K0@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k59_763143_2	1123517.JOMR01000001_gene585	4.01e-12	66.6	COG2980@1|root,COG2980@2|Bacteria,1PSFM@1224|Proteobacteria,1SSE0@1236|Gammaproteobacteria,462X7@72273|Thiotrichales	72273|Thiotrichales	M	Lipopolysaccharide-assembly	-	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
k59_256810_1	1380600.AUYN01000006_gene265	1.95e-42	140.0	COG3609@1|root,COG3609@2|Bacteria,4NSHD@976|Bacteroidetes,1I46W@117743|Flavobacteriia	976|Bacteroidetes	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k59_1332175_1	572480.Arnit_3128	1.12e-73	223.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,42W98@68525|delta/epsilon subdivisions,2YQFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1332175_2	572480.Arnit_3127	2.12e-16	74.7	COG2353@1|root,COG2353@2|Bacteria,1PDM9@1224|Proteobacteria,42TFW@68525|delta/epsilon subdivisions,2YQ0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1555239_1	497321.C664_12325	4.94e-27	106.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,2KVRT@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_1555239_2	497321.C664_12330	2.38e-62	193.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KWPI@206389|Rhodocyclales	206389|Rhodocyclales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_1160261_1	1121931.AUHG01000010_gene535	6.4e-135	392.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1HYIU@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
k59_1669836_1	580332.Slit_2066	4.56e-75	236.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,44V68@713636|Nitrosomonadales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_595690_1	1123326.JFBL01000006_gene1042	7.76e-96	285.0	COG2207@1|root,COG2207@2|Bacteria,1N3SB@1224|Proteobacteria,43AM3@68525|delta/epsilon subdivisions,2YT1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_143708_1	1502770.JQMG01000001_gene2324	5.08e-13	66.6	COG4969@1|root,COG4969@2|Bacteria,1N4MN@1224|Proteobacteria,2VVHM@28216|Betaproteobacteria,2KNTC@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Pilin (bacterial filament)	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
k59_143708_2	870187.Thini_1297	5.28e-26	99.0	2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,4639K@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1555256_1	1178825.ALIH01000006_gene1549	2.04e-151	435.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
k59_1555256_2	1137281.D778_02226	1.8e-30	119.0	COG0642@1|root,COG2203@1|root,COG3290@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_1726193_1	865937.Gilli_0854	1.14e-35	124.0	COG2920@1|root,COG2920@2|Bacteria,4NSKM@976|Bacteroidetes,1I46G@117743|Flavobacteriia	976|Bacteroidetes	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_1726193_2	886379.AEWI01000122_gene1872	7.27e-28	104.0	COG2210@1|root,COG2210@2|Bacteria,4NNB9@976|Bacteroidetes,2FW6V@200643|Bacteroidia	976|Bacteroidetes	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_539683_1	391587.KAOT1_12292	9.25e-37	132.0	2E7WJ@1|root,332B6@2|Bacteria,4NVEC@976|Bacteroidetes,1I555@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_539683_2	504487.JCM19302_3134	5.18e-147	428.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,1HYHT@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_314156_1	1117108.PAALTS15_19903	2.2e-09	60.1	COG0454@1|root,COG0454@2|Bacteria,1UJEF@1239|Firmicutes,4IT6Z@91061|Bacilli,2778J@186822|Paenibacillaceae	91061|Bacilli	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_1273648_1	1121011.AUCB01000022_gene3694	3.69e-36	127.0	28HM7@1|root,2Z7VU@2|Bacteria,4NGV1@976|Bacteroidetes,1HXYU@117743|Flavobacteriia,23H68@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1695532_1	883126.HMPREF9710_01850	5.85e-39	144.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,473HE@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_283335_1	1121931.AUHG01000011_gene1655	4.06e-184	518.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
k59_283335_2	1121931.AUHG01000011_gene1654	1.08e-20	89.4	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1HXZB@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_509065_1	1178825.ALIH01000007_gene1587	4.07e-146	460.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_1469364_1	929558.SMGD1_1106	5.94e-97	293.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2YPEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cation efflux system protein	crdC	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
k59_1469364_2	563040.Saut_2057	1.08e-28	114.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_678880_1	1123228.AUIH01000003_gene790	3.48e-43	163.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1073995_1	392500.Swoo_0819	7.17e-66	213.0	COG2807@1|root,COG2807@2|Bacteria,1MXGT@1224|Proteobacteria,1RNWA@1236|Gammaproteobacteria,2QAZS@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM major facilitator superfamily MFS_1	yeaN	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
k59_1695539_1	1406840.Q763_09725	1.22e-238	707.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,1HZXU@117743|Flavobacteriia,2NTUX@237|Flavobacterium	976|Bacteroidetes	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
k59_226988_1	1121931.AUHG01000010_gene724	9.14e-32	112.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,1I4QG@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_226988_2	1121931.AUHG01000010_gene728	1.34e-115	333.0	28JKT@1|root,2Z9DG@2|Bacteria,4NJJK@976|Bacteroidetes,1HYPI@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
k59_1469370_1	411154.GFO_0489	1.48e-62	200.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1HX12@117743|Flavobacteriia	976|Bacteroidetes	EGP	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k59_1469370_2	411154.GFO_0488	6.53e-20	88.2	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes,1HXED@117743|Flavobacteriia	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114031_1	387093.SUN_0942	7.83e-47	164.0	2A07G@1|root,30NAN@2|Bacteria,1Q58X@1224|Proteobacteria,430TB@68525|delta/epsilon subdivisions,2YRYC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1639156_1	983544.Lacal_1990	1.29e-113	342.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1HXUQ@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1639156_2	1380600.AUYN01000009_gene1595	3.31e-57	185.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_339721_1	1178825.ALIH01000001_gene2578	2.52e-138	401.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_396469_1	1117647.M5M_07520	2.23e-33	131.0	COG2010@1|root,COG3420@1|root,COG2010@2|Bacteria,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,1T2I7@1236|Gammaproteobacteria,1J4SI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3420 Nitrous oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
k59_904844_1	861299.J421_2768	8.62e-99	319.0	COG0086@1|root,COG0086@2|Bacteria,1ZSZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_170526_1	1123518.ARWI01000001_gene1450	3.56e-12	65.5	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales	72273|Thiotrichales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_170526_2	90813.JQMT01000001_gene2143	1.04e-10	63.5	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,1SBZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1130823_1	572480.Arnit_3003	1.6e-113	334.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_791782_1	944547.ABLL_0941	4.46e-23	90.1	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42V7U@68525|delta/epsilon subdivisions,2YSGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1752089_1	411154.GFO_2957	2.39e-170	487.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1HXDR@117743|Flavobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_452918_1	1232410.KI421428_gene1210	5.53e-124	367.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,43TZ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
k59_622423_1	1499685.CCFJ01000051_gene1995	1.21e-11	69.7	COG3935@1|root,COG3935@2|Bacteria,1VCAM@1239|Firmicutes,4HKS4@91061|Bacilli,1ZHP7@1386|Bacillus	91061|Bacilli	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
k59_1413245_1	477184.KYC_19444	5.47e-86	276.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2VM4U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_1356481_1	1484460.JSWG01000015_gene850	1.11e-90	280.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_283377_1	1094466.KQS_05910	1.59e-194	560.0	COG0827@1|root,COG0827@2|Bacteria,4PMS5@976|Bacteroidetes,1I839@117743|Flavobacteriia,2NY03@237|Flavobacterium	976|Bacteroidetes	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
k59_283377_2	1094466.KQS_05915	6.25e-152	435.0	COG0827@1|root,COG0827@2|Bacteria,4NJAP@976|Bacteroidetes	976|Bacteroidetes	L	BsuBI/PstI restriction endonuclease C-terminus	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	BsuBI_PstI_RE,Eco57I
k59_1017833_2	1175654.A0A0S0NAI5_9CAUD	1.55e-70	222.0	4QCT7@10239|Viruses,4QVJT@35237|dsDNA viruses  no RNA stage,4QPFU@28883|Caudovirales,4QKS9@10699|Siphoviridae	10699|Siphoviridae	S	iron-sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1017833_3	1175654.A0A0S0N8S9_9CAUD	4.19e-183	527.0	4QGHR@10239|Viruses,4QWID@35237|dsDNA viruses  no RNA stage,4QTRG@28883|Caudovirales,4QKSH@10699|Siphoviridae	10699|Siphoviridae	S	Queuosine biosynthesis protein QueC	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1017833_4	1353531.AZNX01000018_gene5994	2.32e-36	128.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2UJ9N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_283378_1	1121931.AUHG01000011_gene1797	1.48e-113	328.0	28NPC@1|root,2ZBPA@2|Bacteria,4NMF8@976|Bacteroidetes,1I1A0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1243479_1	1250232.JQNJ01000001_gene96	6.01e-201	570.0	COG3177@1|root,COG3177@2|Bacteria,4NG08@976|Bacteroidetes,1I0BA@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k59_1639194_2	1178825.ALIH01000003_gene2093	3.66e-55	176.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,1I258@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_396503_1	1250005.PHEL85_3273	3.7e-148	429.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia,3VVDN@52959|Polaribacter	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_452934_1	1178825.ALIH01000011_gene45	5.31e-15	76.6	28MB2@1|root,2ZAPM@2|Bacteria,4NM1C@976|Bacteroidetes,1I004@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1582659_1	1121931.AUHG01000010_gene827	2.09e-201	571.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_1017859_1	1086011.HJ01_01409	4.36e-38	145.0	COG3291@1|root,COG3291@2|Bacteria,4NEWJ@976|Bacteroidetes,1HZA6@117743|Flavobacteriia,2P051@237|Flavobacterium	976|Bacteroidetes	MU	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14
k59_1017859_2	1380600.AUYN01000001_gene2703	6.45e-131	375.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrophosphatase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
k59_57641_1	411154.GFO_1857	4.69e-25	105.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57641_2	411154.GFO_1858	5.37e-21	88.6	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k59_848024_1	1123518.ARWI01000001_gene1522	7.85e-66	227.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,4614F@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_9
k59_848024_2	342610.Patl_2135	3.96e-143	417.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2Q164@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_283416_1	392500.Swoo_2609	2.62e-98	293.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,2QAAC@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_59322_1	944547.ABLL_2785	1.69e-49	178.0	COG3287@1|root,COG3437@1|root,COG3287@2|Bacteria,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
k59_793501_1	926559.JoomaDRAFT_1804	2.43e-167	503.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_793501_2	1296416.JACB01000051_gene2695	2.13e-26	105.0	COG3325@1|root,COG3325@2|Bacteria,4PPVV@976|Bacteroidetes,1IKVM@117743|Flavobacteriia,2YIHH@290174|Aquimarina	976|Bacteroidetes	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
k59_737086_3	1453496.AT03_13275	5.09e-53	184.0	COG4834@1|root,COG4834@2|Bacteria,1MZ5H@1224|Proteobacteria,1SCQB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2184)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2184
k59_567526_1	1178825.ALIH01000008_gene776	4.65e-146	437.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_2866_1	1178825.ALIH01000001_gene2385	3.18e-22	89.7	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1I3ZS@117743|Flavobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
k59_2866_2	1469557.JSWF01000045_gene484	4.07e-114	340.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_1019616_1	326298.Suden_1692	2.13e-61	197.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2YNK6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_737093_1	90814.KL370891_gene1593	5.9e-61	192.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,4615Z@72273|Thiotrichales	72273|Thiotrichales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_737093_2	396588.Tgr7_1279	7.43e-46	154.0	COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1S41U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	CT2216	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_510566_1	616991.JPOO01000003_gene2345	1.27e-127	375.0	COG0160@1|root,COG0160@2|Bacteria,4NIHH@976|Bacteroidetes,1IG0C@117743|Flavobacteriia,23ICM@178469|Arenibacter	976|Bacteroidetes	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_2881_1	1380600.AUYN01000007_gene3292	8.18e-114	341.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1HXZF@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
k59_2881_2	1392490.JHZX01000001_gene2046	1.43e-20	90.5	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1357945_1	1380600.AUYN01000003_gene114	1.19e-105	313.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_59363_1	1042377.AFPJ01000004_gene386	1.36e-11	72.0	COG5276@1|root,COG5276@2|Bacteria,1NCJH@1224|Proteobacteria,1SZI3@1236|Gammaproteobacteria,468AW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_228771_1	90814.KL370891_gene574	6.51e-24	95.9	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,460KH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_228771_2	1123514.KB905899_gene1541	4.34e-47	152.0	COG2921@1|root,COG2921@2|Bacteria,1NMJ1@1224|Proteobacteria,1SI79@1236|Gammaproteobacteria,461CF@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k59_285192_1	759914.BP951000_2214	1.83e-12	72.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	lytB	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K06381	-	-	-	-	ko00000	-	-	-	CW_binding_2,PG_binding_1,SH3_3,SpoIID,Y_Y_Y
k59_1019649_1	1122211.JMLW01000007_gene118	4.83e-55	184.0	COG0438@1|root,COG0438@2|Bacteria,1MWU0@1224|Proteobacteria,1RZA8@1236|Gammaproteobacteria,1XPJQ@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
k59_624204_1	1123518.ARWI01000001_gene2389	2.54e-21	93.6	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_624204_2	387093.SUN_1160	5.01e-36	128.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42QT6@68525|delta/epsilon subdivisions,2YR4C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_1470851_1	411154.GFO_2142	9.96e-126	382.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_737121_1	1336233.JAEH01000021_gene3365	3.68e-89	279.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,2QA2R@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0000166,GO:0000900,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004812,GO:0004829,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006435,GO:0006446,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0017076,GO:0017148,GO:0019222,GO:0019538,GO:0019752,GO:0030371,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032553,GO:0032555,GO:0032559,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045947,GO:0046483,GO:0046872,GO:0046914,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097367,GO:0106074,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iPC815.YPO2433,iSDY_1059.SDY_1814	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_398252_1	1123518.ARWI01000001_gene1450	3.92e-154	460.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales	72273|Thiotrichales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_285198_1	497321.C664_10108	2.82e-120	344.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,2KU7I@206389|Rhodocyclales	206389|Rhodocyclales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_1302171_1	1121931.AUHG01000011_gene2185	1.15e-159	451.0	COG1376@1|root,COG1376@2|Bacteria,4NMHM@976|Bacteroidetes,1HZGK@117743|Flavobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_680766_1	1123517.JOMR01000001_gene1507	2.75e-17	80.1	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,460BS@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_285213_1	1249480.B649_00715	2.28e-40	142.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2YME6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylglucosamine 4,6-dehydratase	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_567575_1	1380600.AUYN01000009_gene1963	4.46e-50	170.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_737144_1	504487.JCM19302_2886	6.87e-181	514.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
k59_737144_2	1197477.IA57_12615	2.81e-96	285.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1753950_1	1178825.ALIH01000001_gene2365	7.67e-97	288.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1HXFX@117743|Flavobacteriia	976|Bacteroidetes	D	Required for cell division and gliding motility	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k59_398286_1	387093.SUN_1493	7.84e-155	451.0	COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,1MU1B@1224|Proteobacteria,42QHG@68525|delta/epsilon subdivisions,2YN5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC,Fer4_11,Fer4_4
k59_1470895_1	1122225.AULQ01000006_gene917	1.17e-169	497.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_567588_1	1223410.KN050846_gene2503	7.79e-13	67.4	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_567588_2	411154.GFO_0354	2.91e-179	503.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_172415_1	411154.GFO_1822	3.03e-158	452.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_115824_1	1229487.AMYW01000032_gene3023	6.89e-24	106.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia,2NTD8@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c7 and related cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_1244995_1	317655.Sala_2701	3.36e-12	67.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,2K083@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
k59_1244995_2	1307759.JOMJ01000003_gene793	1.04e-27	108.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,42QZX@68525|delta/epsilon subdivisions,2WN5T@28221|Deltaproteobacteria,2MA07@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
k59_184192_2	1122225.AULQ01000006_gene1171	8.38e-23	90.5	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_296641_1	1380600.AUYN01000009_gene1328	1.46e-53	175.0	COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,1HYY1@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_296641_2	1137281.D778_01171	1.34e-82	248.0	COG1670@1|root,COG1670@2|Bacteria,4NM3W@976|Bacteroidetes,1I1MN@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_71100_1	1336233.JAEH01000016_gene3031	3.51e-71	219.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2QA1R@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_71100_2	1565129.JSFF01000011_gene1900	3.21e-18	81.3	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,2Q9RS@267890|Shewanellaceae	1236|Gammaproteobacteria	G	inositol monophosphatase	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2538,iPC815.YPO2899	Inositol_P
k59_1482940_1	938709.AUSH02000051_gene156	4.43e-06	48.9	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes	976|Bacteroidetes	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_1482940_2	1137281.D778_02343	1.58e-72	221.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,1I266@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
k59_1482940_3	1392490.JHZX01000001_gene862	7.43e-126	360.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1HXSV@117743|Flavobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_1256350_1	765914.ThisiDRAFT_2592	6.16e-34	138.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WXIU@135613|Chromatiales	135613|Chromatiales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_466517_1	1121007.AUML01000014_gene2878	7.33e-301	833.0	COG1328@1|root,COG1328@2|Bacteria,4NFVE@976|Bacteroidetes,1I51J@117743|Flavobacteriia,2YJ96@290174|Aquimarina	976|Bacteroidetes	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_1482945_1	62928.azo0832	1.14e-69	221.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,2KVSV@206389|Rhodocyclales	206389|Rhodocyclales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1482945_2	62928.azo0833	2e-44	154.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,2KU75@206389|Rhodocyclales	206389|Rhodocyclales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1256361_1	504472.Slin_4940	2.26e-36	134.0	COG0438@1|root,COG0438@2|Bacteria,4NJFY@976|Bacteroidetes,47JHM@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_1368784_1	929558.SMGD1_2812	1.29e-31	121.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42Z03@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1368784_2	929558.SMGD1_2811	1.88e-237	659.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_352380_1	411154.GFO_3490	1.88e-122	352.0	COG1018@1|root,COG1018@2|Bacteria,4NM4J@976|Bacteroidetes,1I1RH@117743|Flavobacteriia	976|Bacteroidetes	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FAD_binding_8,NAD_binding_1
k59_352380_2	1121931.AUHG01000010_gene507	2.01e-89	264.0	2DEWP@1|root,2ZPJE@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_352380_3	1121931.AUHG01000010_gene508	2.31e-43	150.0	2E3AK@1|root,2ZCCU@2|Bacteria,4NN6G@976|Bacteroidetes,1I1MB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1652577_1	1353528.DT23_05805	2.6e-144	410.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2XKPC@285107|Thioclava	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_1368806_1	1249975.JQLP01000005_gene1719	5.73e-98	288.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1HXFC@117743|Flavobacteriia,2P69N@244698|Gillisia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
k59_1368806_2	1123037.AUDE01000010_gene2312	3.16e-128	374.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1HY3V@117743|Flavobacteriia	976|Bacteroidetes	M	mandelate racemase	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
k59_240655_1	1353528.DT23_04675	1.57e-160	459.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2TSJV@28211|Alphaproteobacteria,2XKPE@285107|Thioclava	28211|Alphaproteobacteria	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	rbcL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_522346_1	411154.GFO_2933	2.64e-109	338.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_805310_1	367737.Abu_0788	1.27e-05	48.5	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42QY3@68525|delta/epsilon subdivisions,2YNZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,MCPsignal,dCache_1,dCache_2,sCache_2
k59_805310_2	572480.Arnit_0858	5.35e-106	314.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YNB0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	periplasmic solute binding protein	znuA	-	-	ko:K02077,ko:K09815	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
k59_1314199_1	1205680.CAKO01000040_gene667	4.01e-47	158.0	COG0555@1|root,COG0555@2|Bacteria,1NQQ5@1224|Proteobacteria,2TQUP@28211|Alphaproteobacteria,2JPVJ@204441|Rhodospirillales	204441|Rhodospirillales	O	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_1314199_2	1205680.CAKO01000040_gene666	7.48e-42	145.0	COG1177@1|root,COG1177@2|Bacteria,1N0SF@1224|Proteobacteria,2TRZ7@28211|Alphaproteobacteria,2JRMV@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_1482998_1	1380600.AUYN01000009_gene2061	3.06e-56	194.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_917556_1	563040.Saut_1606	4.09e-188	526.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2YMPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_917556_2	1537917.JU82_04060	1.95e-20	89.4	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_353657_1	313598.MED152_11539	2.43e-15	74.7	2DRCR@1|root,33B8F@2|Bacteria,4NUWN@976|Bacteroidetes,1I5E0@117743|Flavobacteriia,3VXE1@52959|Polaribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4174)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4174
k59_1427137_1	1121931.AUHG01000010_gene226	1.03e-86	259.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1HWRK@117743|Flavobacteriia	976|Bacteroidetes	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_1427137_2	1041826.FCOL_08450	7.06e-13	70.5	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2NUYY@237|Flavobacterium	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,MAM,PepSY,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,fn3
k59_580463_1	572480.Arnit_1484	7.49e-39	147.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,Cadherin_3,Calx-beta,SdrD_B
k59_1087605_1	242619.PG_0924	2.23e-35	132.0	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes	976|Bacteroidetes	S	5'-nucleotidase, lipoprotein e(P4) family	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
k59_1087605_2	143224.JQMD01000002_gene159	7.51e-99	291.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1767025_1	504472.Slin_1640	1.84e-40	151.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1087616_1	572480.Arnit_1202	4.88e-125	384.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43E1J@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,SBP_bac_3,dCache_2,dCache_3
k59_353690_1	323850.Shew_1939	4.74e-32	113.0	COG3139@1|root,COG3139@2|Bacteria,1N6T3@1224|Proteobacteria,1SCFV@1236|Gammaproteobacteria,2QCHA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1315)	yeaC	-	-	ko:K09916	-	-	-	-	ko00000	-	-	-	DUF1315
k59_353690_2	1565129.JSFF01000028_gene723	8.44e-66	209.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RMUB@1236|Gammaproteobacteria,2Q8W7@267890|Shewanellaceae	1236|Gammaproteobacteria	EJ	PFAM Asparaginase glutaminase	ansA	GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1961,iSF_1195.SF1456,iS_1188.S1571,iYL1228.KPN_01203	Asparaginase
k59_1032217_1	926562.Oweho_2246	0.000111	50.4	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4PPAH@976|Bacteroidetes,1IKHA@117743|Flavobacteriia,2PBN6@246874|Cryomorphaceae	2|Bacteria	M	Fibronectin type 3 domain	-	-	3.4.24.40	ko:K01406,ko:K20276	ko01503,ko02024,map01503,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CHU_C,Laminin_G_3,MAM,PKD
k59_1539776_1	1305737.JAFX01000001_gene3591	3.24e-47	156.0	COG4539@1|root,COG4539@2|Bacteria,4NQIX@976|Bacteroidetes,47Q6B@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
k59_185558_1	118161.KB235922_gene2014	3.12e-19	92.4	COG0642@1|root,COG1340@1|root,COG1352@1|root,COG2201@1|root,COG1340@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3VKY4@52604|Pleurocapsales	1117|Cyanobacteria	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,Response_reg
k59_973170_2	1123514.KB905899_gene1907	6.42e-124	366.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,46033@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,OEP
k59_1315539_1	1122225.AULQ01000007_gene2223	4.43e-57	179.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1I1A9@117743|Flavobacteriia	976|Bacteroidetes	I	hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
k59_1315539_2	1392488.JHZY01000004_gene3073	3.82e-22	94.7	COG0644@1|root,COG0644@2|Bacteria,4NDTU@976|Bacteroidetes,1HYHZ@117743|Flavobacteriia	976|Bacteroidetes	C	lycopene cyclase	crtY	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
k59_1427182_1	1121931.AUHG01000010_gene726	9.97e-41	148.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,1HX6A@117743|Flavobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein	mutS_2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
k59_1427182_2	1121931.AUHG01000010_gene727	1.44e-77	231.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1I2YP@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
k59_128127_2	357804.Ping_2696	1.38e-23	98.6	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RY7R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1653897_1	1111730.ATTM01000005_gene108	1.87e-91	299.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia,2P0JG@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_14668_4	195105.CN97_00755	2.17e-29	122.0	COG2369@1|root,COG2369@2|Bacteria,1P87U@1224|Proteobacteria,2TSNA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	head morphogenesis protein, SPP1	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_14668_5	562742.F4YXT2_9CAUD	1.5e-46	154.0	4QCE9@10239|Viruses,4QXGI@35237|dsDNA viruses  no RNA stage,4QPHG@28883|Caudovirales	28883|Caudovirales	S	Pfam:Peptidase_S78_2	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14668_14	562742.F4YXT9_9CAUD	1.52e-42	155.0	4QG8X@10239|Viruses,4QVDN@35237|dsDNA viruses  no RNA stage,4QSBT@28883|Caudovirales,4QM55@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1370136_1	572480.Arnit_1728	1.77e-143	426.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_918770_1	929558.SMGD1_0427	1.27e-84	270.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2YMZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_918770_2	929558.SMGD1_0426	2.51e-61	199.0	COG0265@1|root,COG0265@2|Bacteria,1NVFS@1224|Proteobacteria,42Z4E@68525|delta/epsilon subdivisions,2YRIR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase s1	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_637242_1	572480.Arnit_0512	1.51e-221	636.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_410997_1	1178825.ALIH01000003_gene2191	1.93e-135	394.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1HXWF@117743|Flavobacteriia	976|Bacteroidetes	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k59_1427207_1	1237149.C900_04526	1.94e-74	237.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_749393_1	563040.Saut_0071	2.98e-43	160.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YT16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1710427_1	1178825.ALIH01000005_gene359	7.48e-104	305.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1HYZ1@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
k59_467901_1	1172190.M947_10255	8.3e-57	199.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_467915_1	1480694.DC28_04830	1.26e-51	173.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
k59_973216_1	1137281.D778_01157	1.27e-145	417.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,1HY21@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX amino terminal protease family	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_1484371_1	1353528.DT23_03080	8.64e-142	408.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,2XMHJ@285107|Thioclava	28211|Alphaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_918810_1	592029.DDD_0826	8.29e-51	180.0	COG1479@1|root,COG1479@2|Bacteria,4NE8H@976|Bacteroidetes,1I0JR@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
k59_694318_1	1392489.JPOL01000002_gene2247	6.92e-144	420.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1HZF1@117743|Flavobacteriia,2XK56@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Maltogenic Amylase, C-terminal domain	malL	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_806720_1	1298593.TOL_2673	5.92e-53	174.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1XIC2@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_806720_2	498211.CJA_0958	1.47e-109	327.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1FG5V@10|Cellvibrio	1236|Gammaproteobacteria	E	Branched-chain amino acid transport system / permease component	fmdF	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_1315622_1	1353276.JADR01000010_gene1611	4.34e-98	292.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_411057_1	1123518.ARWI01000001_gene1730	5.17e-142	411.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1370205_1	1392490.JHZX01000001_gene2157	1.65e-56	195.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4PKKM@976|Bacteroidetes,1HYM7@117743|Flavobacteriia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_1370205_2	1122225.AULQ01000004_gene1975	1.77e-35	124.0	COG2198@1|root,COG2198@2|Bacteria,4NVD5@976|Bacteroidetes,1I5CS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_1370205_3	1178825.ALIH01000002_gene962	4.64e-104	308.0	COG3279@1|root,COG3279@2|Bacteria,4NHUZ@976|Bacteroidetes,1HY5V@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_1767163_1	1392489.JPOL01000002_gene1356	4.51e-29	119.0	28I8D@1|root,2Z8B7@2|Bacteria,4NN38@976|Bacteroidetes,1IIB2@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
k59_918854_1	1392488.JHZY01000004_gene1973	1.46e-103	304.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,1HWTV@117743|Flavobacteriia,2XIPQ@283735|Leeuwenhoekiella	976|Bacteroidetes	IQ	KR domain	kduD	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
k59_694356_1	1492737.FEM08_09550	1.97e-25	109.0	COG3119@1|root,COG3119@2|Bacteria,4NE7S@976|Bacteroidetes,1I2RA@117743|Flavobacteriia,2NVTT@237|Flavobacterium	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_1271604_2	1336233.JAEH01000007_gene2515	5.02e-50	163.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,2QAJ2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM cytochrome C oxidase mono-heme subunit FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_1271604_3	323850.Shew_1986	1.26e-72	221.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,2QAJ2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM cytochrome C oxidase mono-heme subunit FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_1271604_4	1565129.JSFF01000003_gene2251	8.74e-30	105.0	COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,2QCSE@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM Cbb3-type cytochrome oxidase component	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_1271604_5	1565129.JSFF01000003_gene2250	5.92e-45	153.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,2Q8VP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
k59_367298_1	1123518.ARWI01000001_gene896	1.59e-43	149.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,45ZSB@72273|Thiotrichales	72273|Thiotrichales	M	Arabinose 5-phosphate isomerase	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_367298_2	317025.Tcr_0504	5.9e-70	217.0	COG3637@1|root,COG3637@2|Bacteria,1N7IC@1224|Proteobacteria,1SI8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PagL
k59_199426_3	411154.GFO_3077	1.76e-44	154.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_86351_1	1002804.HBZC1_07130	1.21e-06	46.6	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2YQ0A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_86351_2	1172190.M947_09185	1.19e-59	184.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2YPJ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_762880_1	1250232.JQNJ01000001_gene3001	7.06e-158	459.0	COG0521@1|root,COG0521@2|Bacteria,4PKAT@976|Bacteroidetes,1IKAW@117743|Flavobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
k59_1440555_1	626887.J057_05966	1.27e-120	353.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,1RVY8@1236|Gammaproteobacteria,46AAT@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k59_932150_2	1178825.ALIH01000008_gene788	1.1e-130	374.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1HX41@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_932150_3	313603.FB2170_00655	3.77e-23	90.1	2E50X@1|root,32ZUB@2|Bacteria,4NW9R@976|Bacteroidetes,1I57F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_932150_4	1380600.AUYN01000006_gene273	2.8e-85	258.0	COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,1HZWT@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_424820_1	156889.Mmc1_2528	1.6e-55	187.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	rsbP	-	3.1.3.3	ko:K07315,ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko03021	-	-	-	HATPase_c_2,PAS_9,Response_reg,SpoIIE
k59_424820_2	1112212.JH584235_gene3330	1.36e-16	82.8	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2K8N8@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1329956_1	1137281.D778_01916	1.04e-124	377.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1725863_2	1121931.AUHG01000012_gene2518	1.89e-40	134.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1I3W1@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_764661_2	1232410.KI421417_gene2734	2.24e-46	166.0	2E2HF@1|root,32XMD@2|Bacteria,1N5B9@1224|Proteobacteria,42WRZ@68525|delta/epsilon subdivisions,2WRVW@28221|Deltaproteobacteria,43VYK@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201110_1	948106.AWZT01000039_gene1168	3.37e-67	211.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VIBS@28216|Betaproteobacteria,1K3GU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Pro_CA
k59_29632_1	1172190.M947_10610	4.46e-71	235.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42PDD@68525|delta/epsilon subdivisions,2YMYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_539386_1	1565129.JSFF01000002_gene3443	4.63e-96	300.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q95C@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_369138_1	1380600.AUYN01000009_gene1765	2.08e-82	269.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1103161_1	1380600.AUYN01000009_gene1319	5.18e-36	126.0	2DM2K@1|root,31G7J@2|Bacteria,4NQIU@976|Bacteroidetes,1I2UQ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_1103161_2	1137281.D778_00738	1.14e-72	225.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1HXRU@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1554992_1	563040.Saut_1857	8.28e-115	336.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2YN2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_1554992_2	1172190.M947_07720	9.05e-63	199.0	2AJSF@1|root,30P8S@2|Bacteria,1PCR0@1224|Proteobacteria,42WCR@68525|delta/epsilon subdivisions,2YSXN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_1554992_3	1172190.M947_07725	2.74e-05	45.1	2AK36@1|root,31ASY@2|Bacteria,1Q62K@1224|Proteobacteria,42W11@68525|delta/epsilon subdivisions,2YQDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
k59_1442292_1	85643.Tmz1t_1554	2.64e-36	132.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,2KURQ@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_595440_1	1237149.C900_03098	2.1e-75	241.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,47NRA@768503|Cytophagia	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_595440_2	1121895.Q765_12600	6.22e-06	47.8	COG0745@1|root,COG0745@2|Bacteria,4NGI5@976|Bacteroidetes,1HZWI@117743|Flavobacteriia,2NS62@237|Flavobacterium	976|Bacteroidetes	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1554993_1	351348.Maqu_0609	4.63e-141	410.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,1RRNV@1236|Gammaproteobacteria,46D6X@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_32,HTH_33
k59_823276_1	1172190.M947_06330	1.05e-82	259.0	COG0658@1|root,COG0658@2|Bacteria,1PY6P@1224|Proteobacteria,42NU2@68525|delta/epsilon subdivisions,2YME0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Competence protein	comE	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
k59_369178_1	1137281.D778_00950	0.0	1004.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1554999_1	637910.ROD_01351	5.16e-16	78.2	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,3WZ69@544|Citrobacter	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1442304_1	493475.GARC_2568	8.4e-121	364.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,465RT@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_878262_1	1380600.AUYN01000001_gene2458	7.89e-69	211.0	2AISX@1|root,3199U@2|Bacteria,4NQ7A@976|Bacteroidetes,1I3B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_764729_1	411154.GFO_3374	1.31e-51	176.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_764729_2	1250278.JQNQ01000001_gene1808	5.71e-16	77.4	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_878265_1	1168067.JAGP01000001_gene1589	7.82e-06	47.8	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,460GY@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_878265_2	1123518.ARWI01000001_gene673	1.05e-66	210.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,460HY@72273|Thiotrichales	72273|Thiotrichales	N	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_986347_1	62928.azo2524	1.31e-104	311.0	COG0583@1|root,COG0583@2|Bacteria,1MV36@1224|Proteobacteria,2VID0@28216|Betaproteobacteria,2KY10@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_143452_1	991.IW20_24810	7.51e-99	313.0	COG0610@1|root,COG3206@1|root,COG0610@2|Bacteria,COG3206@2|Bacteria,4NFJ8@976|Bacteroidetes,1HXHQ@117743|Flavobacteriia,2NT10@237|Flavobacterium	976|Bacteroidetes	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k59_652939_1	85643.Tmz1t_2792	1.46e-72	233.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
k59_1669611_1	1123228.AUIH01000024_gene3266	2.93e-105	313.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XH22@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_201205_1	709032.Sulku_1680	2.64e-48	168.0	COG0582@1|root,COG0582@2|Bacteria,1QYDC@1224|Proteobacteria,43CBN@68525|delta/epsilon subdivisions,2YQ27@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1442327_1	1380600.AUYN01000007_gene3035	4.76e-230	655.0	COG1404@1|root,COG2866@1|root,COG1404@2|Bacteria,COG2866@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Peptidase_S8,fn3
k59_1442327_2	1137281.D778_02642	1.97e-12	65.1	2ENP3@1|root,33GAF@2|Bacteria,4NZ0D@976|Bacteroidetes,1I70X@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1442327_3	1071679.BG57_23235	5.05e-105	319.0	COG0189@1|root,COG0189@2|Bacteria,1QXHP@1224|Proteobacteria,2WH4J@28216|Betaproteobacteria	28216|Betaproteobacteria	HJ	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k59_1442327_4	153721.MYP_1215	7.59e-72	218.0	COG0346@1|root,COG0346@2|Bacteria,4NQXE@976|Bacteroidetes,47QV1@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_1442327_5	153721.MYP_1214	1.23e-55	177.0	COG2207@1|root,COG2207@2|Bacteria,4NPKU@976|Bacteroidetes,47SE6@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_483736_1	709032.Sulku_1553	1.77e-12	66.6	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42VWM@68525|delta/epsilon subdivisions,2YQKK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0714 MoxR-like	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_483736_2	572480.Arnit_0271	2.79e-60	198.0	COG3864@1|root,COG3864@2|Bacteria,1Q995@1224|Proteobacteria,42YHV@68525|delta/epsilon subdivisions,2YRK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_652956_1	228410.NE1319	8.21e-07	53.1	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,3738Z@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_369239_1	388413.ALPR1_17858	2.47e-73	236.0	COG0436@1|root,COG0436@2|Bacteria,4NJEW@976|Bacteroidetes,47TQQ@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1047519_1	1121012.AUKX01000002_gene3404	3.04e-152	447.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1HY1A@117743|Flavobacteriia,23GQN@178469|Arenibacter	976|Bacteroidetes	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
k59_1047519_2	1380600.AUYN01000006_gene677	0.0	951.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1047519_3	1046627.BZARG_423	8.27e-51	162.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1I5R2@117743|Flavobacteriia	976|Bacteroidetes	C	COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit)	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_1047519_4	1380600.AUYN01000006_gene498	2.13e-121	357.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
k59_1047519_5	391603.FBALC1_16867	1.44e-52	175.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
k59_29748_1	1469557.JSWF01000029_gene3283	1.17e-08	55.8	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1332015_1	317025.Tcr_0172	5.69e-39	143.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales	72273|Thiotrichales	E	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_764828_1	90814.KL370892_gene1948	1.7e-77	236.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,460I5@72273|Thiotrichales	72273|Thiotrichales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_764828_2	317025.Tcr_0024	3.2e-54	182.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,45ZU4@72273|Thiotrichales	72273|Thiotrichales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_986449_1	929558.SMGD1_1238	3.51e-95	299.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_539535_1	323850.Shew_2501	2.73e-137	395.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,2Q8QP@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	sapF	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008144,GO:0008150,GO:0008324,GO:0008519,GO:0009987,GO:0015075,GO:0015101,GO:0015203,GO:0015489,GO:0015672,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0017076,GO:0022857,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071804,GO:0071805,GO:0072488,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363,GO:1902047	-	ko:K02031,ko:K02032,ko:K13896,ko:K19229,ko:K19230	ko01503,ko02010,ko02024,map01503,map02010,map02024	M00239,M00349,M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24,3.A.1.5.5	-	iYL1228.KPN_01288	ABC_tran,oligo_HPY
k59_539535_2	225849.swp_3255	5.16e-23	94.4	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,2QAU0@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM ABC transporter related	sapF	-	-	ko:K02031,ko:K02032,ko:K13896,ko:K19229,ko:K19230	ko01503,ko02010,ko02024,map01503,map02010,map02024	M00239,M00349,M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24,3.A.1.5.5	-	-	ABC_tran,oligo_HPY
k59_1047551_1	388413.ALPR1_04353	1.66e-23	97.4	COG0561@1|root,COG0561@2|Bacteria,4NICE@976|Bacteroidetes,47XRS@768503|Cytophagia	976|Bacteroidetes	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_1047551_2	641526.ADIWIN_3860	1.47e-28	115.0	COG0823@1|root,COG3291@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_878365_1	1449347.JQLN01000001_gene381	1.03e-07	52.8	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,2M45G@2063|Kitasatospora	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_878365_2	317025.Tcr_1463	3.38e-54	182.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,46291@72273|Thiotrichales	72273|Thiotrichales	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	-	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k59_1332035_1	1121912.AUHD01000007_gene469	4.92e-88	276.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1HWTC@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1103313_1	1178825.ALIH01000008_gene696	2.52e-101	300.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1HZU1@117743|Flavobacteriia	976|Bacteroidetes	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_1103313_2	504487.JCM19302_3109	4.07e-79	235.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1I1ZH@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_1103313_3	1380600.AUYN01000009_gene1790	2.29e-28	113.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_426790_1	1197477.IA57_11655	1.86e-147	424.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_539569_2	1347342.BN863_32190	1.36e-60	192.0	COG2146@1|root,COG2146@2|Bacteria,4NP7U@976|Bacteroidetes,1I3AW@117743|Flavobacteriia	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_539569_3	1347342.BN863_32180	8.77e-10	56.6	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_823455_1	1123518.ARWI01000001_gene1698	1.46e-128	381.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,4605W@72273|Thiotrichales	72273|Thiotrichales	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_1385726_1	1565129.JSFF01000004_gene3141	4.25e-75	228.0	COG3109@1|root,COG3109@2|Bacteria,1N68T@1224|Proteobacteria,1RP4S@1236|Gammaproteobacteria,2Q9M0@267890|Shewanellaceae	1236|Gammaproteobacteria	T	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities	proQ	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006974,GO:0007154,GO:0007165,GO:0007231,GO:0008150,GO:0009628,GO:0009651,GO:0009987,GO:0010468,GO:0010608,GO:0010958,GO:0019222,GO:0023052,GO:0032879,GO:0032890,GO:0032892,GO:0033554,GO:0033592,GO:0034057,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0042538,GO:0042710,GO:0043269,GO:0043270,GO:0044010,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051704,GO:0051716,GO:0051952,GO:0051954,GO:0051955,GO:0051957,GO:0060255,GO:0065007,GO:0070881,GO:0071214,GO:0071470,GO:0071472,GO:0071474,GO:0071475,GO:0097159,GO:0097617,GO:0104004,GO:1901363,GO:1902834,GO:1902836,GO:1903789,GO:1903793,GO:1903959,GO:1903961,GO:1904062,GO:1904064	-	ko:K03607	-	-	-	-	ko00000	-	-	-	ProQ,ProQ_C
k59_314041_1	223926.28809511	2.96e-89	273.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XW26@135623|Vibrionales	135623|Vibrionales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_314041_2	223926.28809512	1.59e-53	174.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,1SI75@1236|Gammaproteobacteria,1XWMS@135623|Vibrionales	135623|Vibrionales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
k59_388633_2	525898.Sdel_1013	2.28e-24	102.0	2BNRQ@1|root,32HF7@2|Bacteria,1PA1V@1224|Proteobacteria,42SBU@68525|delta/epsilon subdivisions,2YPMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
k59_841457_3	1492738.FEM21_28180	7.36e-96	286.0	2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,1IIH7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
k59_841457_4	1249997.JHZW01000002_gene1707	2.46e-143	409.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_390773_1	345219.Bcoa_1126	4.12e-22	91.3	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus	91061|Bacilli	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k59_390773_2	929558.SMGD1_0503	2.7e-87	263.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,42QY6@68525|delta/epsilon subdivisions,2YNYW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the inositol monophosphatase superfamily	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k59_1125160_1	1565129.JSFF01000004_gene3231	6.38e-139	424.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,2Q9EM@267890|Shewanellaceae	1236|Gammaproteobacteria	KL	PFAM SNF2-related protein	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SWIM
k59_335813_1	1123514.KB905899_gene437	2.19e-106	317.0	COG1215@1|root,COG1215@2|Bacteria,1QVXA@1224|Proteobacteria,1T2MS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
k59_335813_2	1123514.KB905899_gene436	5.72e-34	123.0	COG3148@1|root,COG3148@2|Bacteria	2|Bacteria	S	PFAM DTW domain containing protein	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
k59_504807_1	317025.Tcr_1777	1.58e-145	425.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K12340,ko:K12538	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00328,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,1.B.17.1,2.A.6.2	-	-	OEP
k59_504807_2	317025.Tcr_1776	6.27e-17	75.5	COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,461CR@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_674923_1	1249480.B649_05390	1.18e-66	218.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YNK4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_1353952_1	929558.SMGD1_0303	8.18e-75	237.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
k59_1067349_1	1380600.AUYN01000009_gene2002	1.61e-196	555.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HYE9@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_335835_1	929558.SMGD1_1888	2.32e-80	243.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,42NNI@68525|delta/epsilon subdivisions,2YNBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
k59_335835_2	929558.SMGD1_1889	3.64e-31	110.0	2BSV5@1|root,32MYQ@2|Bacteria,1Q3GB@1224|Proteobacteria,42XA1@68525|delta/epsilon subdivisions,2YQPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_335835_3	929558.SMGD1_1890	6.72e-49	160.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2YN8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_786906_1	1353276.JADR01000002_gene2069	2.07e-89	283.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_110108_1	1178825.ALIH01000002_gene914	3.12e-47	155.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia	976|Bacteroidetes	O	general stress protein	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
k59_110108_2	1197477.IA57_00305	9.56e-44	158.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_164251_1	572480.Arnit_0225	4.84e-106	310.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2YMC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566	DAP_epimerase
k59_1691377_1	1178825.ALIH01000001_gene2529	5.24e-68	219.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_164258_1	572480.Arnit_0818	4.03e-76	248.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,43019@68525|delta/epsilon subdivisions,2YRSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_504863_1	323850.Shew_2339	1.96e-97	287.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,2Q9QF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Pfam:DUF479	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	ACP_PD
k59_1295092_1	1123518.ARWI01000001_gene776	8.15e-109	338.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,45ZPD@72273|Thiotrichales	72273|Thiotrichales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_733664_1	555778.Hneap_0857	1.25e-37	130.0	COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,1S4RE@1236|Gammaproteobacteria,1WY1Y@135613|Chromatiales	135613|Chromatiales	FJ	CMP dCMP deaminase, zinc-binding	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_733664_2	1123518.ARWI01000001_gene473	1.92e-47	163.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,1RQNB@1236|Gammaproteobacteria,462FD@72273|Thiotrichales	72273|Thiotrichales	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
k59_1691397_1	1219084.AP014508_gene2048	2.94e-05	46.6	COG0426@1|root,COG0426@2|Bacteria,2GCP3@200918|Thermotogae	200918|Thermotogae	C	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1354027_1	572480.Arnit_1240	3.31e-36	125.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42SKP@68525|delta/epsilon subdivisions,2YP6Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k59_1354027_2	572480.Arnit_1239	2.65e-67	214.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,42UBS@68525|delta/epsilon subdivisions,2YQ51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_674999_1	1121011.AUCB01000001_gene557	4.35e-58	192.0	COG2207@1|root,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1HX7J@117743|Flavobacteriia,23GF0@178469|Arenibacter	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
k59_559182_1	1122604.JONR01000003_gene1498	1.5e-25	107.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,1S04D@1236|Gammaproteobacteria,1X51D@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1227627_1	563040.Saut_2074	3.61e-86	257.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,42RXC@68525|delta/epsilon subdivisions,2YP4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	esterase of the alpha beta hydrolase fold	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
k59_1227627_2	1537915.JU57_04605	8.88e-39	139.0	COG1672@1|root,COG1672@2|Bacteria,1PZGT@1224|Proteobacteria,42QN9@68525|delta/epsilon subdivisions,2YNKC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_335901_1	1123487.KB892841_gene4306	1.02e-25	105.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,2KUXR@206389|Rhodocyclales	206389|Rhodocyclales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_335901_2	671143.DAMO_1892	8.65e-19	79.3	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
k59_335901_3	518766.Rmar_2421	7.58e-08	51.6	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
k59_559196_1	1185766.DL1_21065	8.7e-82	263.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,2TUPI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CI	phenylacetic acid degradation protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh,MaoC_dehydratas
k59_504902_1	1123517.JOMR01000001_gene415	8.15e-70	220.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,4611Q@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_1295137_1	411154.GFO_0201	5.92e-145	419.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
k59_898851_1	1168067.JAGP01000001_gene1232	7.62e-06	47.4	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_898851_2	1123514.KB905899_gene1596	5.38e-126	360.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,460ET@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_898851_3	1123514.KB905899_gene1597	3.79e-77	236.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,460AV@72273|Thiotrichales	72273|Thiotrichales	S	NGG1p interacting factor 3	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_1008118_1	458817.Shal_0810	1.04e-154	446.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,2Q8JQ@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_841585_1	572480.Arnit_2881	7.98e-97	291.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2YMBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_504923_1	572480.Arnit_0250	4.33e-119	349.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2YN44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_335951_1	1380600.AUYN01000006_gene702	1.92e-105	327.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1HWZI@117743|Flavobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_1405656_1	944547.ABLL_1150	4.18e-63	206.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_222660_1	411154.GFO_2999	5.39e-87	285.0	COG0784@1|root,COG1520@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1520@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NK8Q@976|Bacteroidetes,1IMWE@117743|Flavobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HTH_18,Reg_prop,SpoIIE,Y_Y_Y
k59_447630_1	1178825.ALIH01000007_gene1582	1.94e-68	225.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
k59_447630_2	1380600.AUYN01000009_gene959	2.81e-171	483.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HXMP@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_447651_1	1123234.AUKI01000024_gene2189	1.16e-115	341.0	COG3547@1|root,COG3547@2|Bacteria,4NF2F@976|Bacteroidetes,1HXCM@117743|Flavobacteriia	976|Bacteroidetes	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_898923_1	563040.Saut_1943	2.59e-76	233.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_335986_1	326427.Cagg_0841	2.49e-66	225.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
k59_222693_1	926559.JoomaDRAFT_3924	1.42e-27	107.0	COG3650@1|root,COG3650@2|Bacteria,4PPA7@976|Bacteroidetes,1IKGX@117743|Flavobacteriia	976|Bacteroidetes	S	response to hydrogen peroxide	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_222693_2	1127673.GLIP_3860	1.41e-41	145.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,466TB@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Carboxylesterase family	aes	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
k59_222693_3	1250005.PHEL85_2086	2.16e-13	69.7	COG0265@1|root,COG0657@1|root,COG0265@2|Bacteria,COG0657@2|Bacteria,4PKDQ@976|Bacteroidetes,1HXR3@117743|Flavobacteriia	976|Bacteroidetes	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_898931_1	684949.ATTJ01000003_gene3315	2.21e-49	173.0	COG0376@1|root,COG0376@2|Bacteria,1WMC8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Peroxidase	-	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_1227737_2	1121931.AUHG01000010_gene753	4.21e-34	125.0	COG0564@1|root,COG0564@2|Bacteria,4NGY7@976|Bacteroidetes,1HYYW@117743|Flavobacteriia	976|Bacteroidetes	J	Pseudouridine synthase, RluA family	-	-	5.4.99.23,5.4.99.26	ko:K06175,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_1067551_1	563040.Saut_1796	1.1e-128	389.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1067553_1	519989.ECTPHS_07856	1.03e-45	162.0	COG2199@1|root,COG3706@2|Bacteria,1R51K@1224|Proteobacteria,1SYWV@1236|Gammaproteobacteria,1X2JP@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1522958_1	572480.Arnit_2062	1.49e-36	134.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2YMBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_1522958_2	563040.Saut_1786	7.61e-32	121.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_615083_1	1304888.ATWF01000001_gene1617	7.95e-51	177.0	COG0642@1|root,COG2205@2|Bacteria,2GGJR@200930|Deferribacteres	200930|Deferribacteres	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_787100_1	1380600.AUYN01000001_gene2929	2.29e-136	394.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,1HX5R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_787100_2	1197477.IA57_08740	3.69e-89	264.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1I189@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
k59_110315_1	929558.SMGD1_2276	4.89e-52	173.0	COG0810@1|root,COG0810@2|Bacteria,1QAAM@1224|Proteobacteria,42X9R@68525|delta/epsilon subdivisions,2YQQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
k59_110315_2	929558.SMGD1_2277	1.46e-121	359.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_733822_1	411154.GFO_1853	6.03e-126	381.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1295267_1	504487.JCM19302_880	2.16e-39	140.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1295267_2	385682.AFSL01000006_gene2342	5.92e-13	68.2	COG1106@1|root,COG1106@2|Bacteria,4NE5J@976|Bacteroidetes,2FQDP@200643|Bacteroidia,3XKQF@558415|Marinilabiliaceae	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k59_1227780_1	1121931.AUHG01000010_gene793	1.09e-65	203.0	2E22F@1|root,32XA2@2|Bacteria,4NUIT@976|Bacteroidetes,1I45V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5004,Lipocalin_4
k59_391028_1	929558.SMGD1_1696	9.99e-66	223.0	COG4783@1|root,COG4783@2|Bacteria,1QZ2M@1224|Proteobacteria,43CEP@68525|delta/epsilon subdivisions,2YTC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1575838_1	1172190.M947_00985	1.29e-57	195.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1575838_2	563040.Saut_1038	4.8e-10	59.3	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,430TX@68525|delta/epsilon subdivisions,2YS1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
k59_841722_1	411154.GFO_3183	1.95e-112	352.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_222763_1	563040.Saut_0919	7.29e-108	326.0	COG0539@1|root,COG1107@1|root,COG0539@2|Bacteria,COG1107@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1067624_1	1121940.AUDZ01000006_gene326	8.02e-07	52.4	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XH4C@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1067624_2	1122236.KB905142_gene361	2.7e-13	68.6	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,2KKS8@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1354237_1	1123228.AUIH01000033_gene2667	1.89e-23	101.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XIKF@135619|Oceanospirillales	135619|Oceanospirillales	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_615131_1	1121931.AUHG01000019_gene3034	1.56e-52	174.0	COG1577@1|root,COG1577@2|Bacteria,4NEXC@976|Bacteroidetes,1HY6C@117743|Flavobacteriia	976|Bacteroidetes	I	GHMP Kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_615131_2	1121931.AUHG01000019_gene3035	1.41e-47	163.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
k59_1295320_1	1237149.C900_03125	1.08e-42	157.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
k59_1575878_1	563040.Saut_1651	3.14e-98	296.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_615154_1	62928.azo2989	3.15e-105	324.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KV5J@206389|Rhodocyclales	206389|Rhodocyclales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_505121_1	643867.Ftrac_2419	5.28e-108	323.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,47JKQ@768503|Cytophagia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_841790_1	471870.BACINT_02241	1.61e-35	132.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,2FMHD@200643|Bacteroidia,4AM4U@815|Bacteroidaceae	976|Bacteroidetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_222817_1	1232410.KI421418_gene2329	2.41e-87	266.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42PM8@68525|delta/epsilon subdivisions,2WM7J@28221|Deltaproteobacteria,43SB8@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_615176_1	929558.SMGD1_0192	2.55e-106	330.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42NJQ@68525|delta/epsilon subdivisions,2YMZP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	hmm pf00563	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_391127_1	745718.JADT01000001_gene2033	2.71e-84	261.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_1523085_1	626887.J057_15095	2.11e-86	281.0	COG2273@1|root,COG5498@1|root,COG2273@2|Bacteria,COG5498@2|Bacteria,1R4DU@1224|Proteobacteria,1RR8D@1236|Gammaproteobacteria,464IN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF5011,Glyco_hydro_81
k59_505137_1	1123514.KB905899_gene1994	5.83e-78	238.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,1S0KZ@1236|Gammaproteobacteria,463AF@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_1196023_1	504487.JCM19302_746	2.04e-230	645.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia	976|Bacteroidetes	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1196023_2	504487.JCM19302_747	5.18e-116	344.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia	976|Bacteroidetes	M	Biotin attachment protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
k59_635486_1	411154.GFO_2184	4.5e-105	306.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1HX3V@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
k59_860817_1	525244.HMPREF0023_0668	7.91e-27	112.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,3NIJN@468|Moraxellaceae	1236|Gammaproteobacteria	CP	Proton-conducting membrane transporter	phaD	-	1.6.5.3	ko:K00342,ko:K05561,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M
k59_1085990_1	411154.GFO_0538	1.85e-111	337.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HY5T@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1255992_1	637905.SVI_3901	5.3e-20	88.2	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,2QA78@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
k59_1255992_2	225849.swp_4723	1.53e-26	100.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1SA5G@1236|Gammaproteobacteria,2QA6Q@267890|Shewanellaceae	1236|Gammaproteobacteria	K	transcriptional regulator, MerR family	zntR	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K08365,ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
k59_1142674_1	1121931.AUHG01000012_gene2656	1.76e-61	194.0	COG2114@1|root,COG2114@2|Bacteria,4PKG4@976|Bacteroidetes,1IJYX@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	SatD
k59_1255995_1	572480.Arnit_1810	1.51e-122	365.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2YMSG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.6,3.1.4.16	ko:K01119,ko:K17224	ko00230,ko00240,ko00920,ko01100,ko01120,map00230,map00240,map00920,map01100,map01120	M00595	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135,R10151	RC00078,RC00296,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_1368388_1	572480.Arnit_2491	9.05e-34	123.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2YT6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_1368388_2	572480.Arnit_2490	1.88e-106	312.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2YMT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	motP	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_352015_1	572480.Arnit_1023	8.78e-93	291.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1NU9A@1224|Proteobacteria,42YSZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,dCache_2
k59_1085992_1	1137281.D778_01652	0.0	914.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1030569_2	671143.DAMO_0821	2.52e-26	107.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_1596053_1	326298.Suden_1359	1.05e-111	333.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2YMUP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	na -driven multidrug efflux	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_1596053_2	929558.SMGD1_2309	1.92e-33	117.0	2BJZK@1|root,32ECD@2|Bacteria,1QDIV@1224|Proteobacteria,433KD@68525|delta/epsilon subdivisions,2YSRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1196029_1	983544.Lacal_1516	5.65e-100	304.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan synthetase	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1196029_2	1380600.AUYN01000009_gene1325	1.68e-157	449.0	COG0457@1|root,COG0457@2|Bacteria,4NG9G@976|Bacteroidetes,1HYXF@117743|Flavobacteriia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
k59_1030580_1	1565129.JSFF01000002_gene3395	3.85e-182	548.0	COG0439@1|root,COG0777@1|root,COG0825@1|root,COG0439@2|Bacteria,COG0777@2|Bacteria,COG0825@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,2Q9WE@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2,Carboxyl_trans
k59_1196045_2	1439940.BAY1663_00526	5.13e-10	59.7	COG2885@1|root,COG2885@2|Bacteria,1R6QU@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	MA20_39345	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_296335_1	411154.GFO_3407	9.05e-250	687.0	COG2865@1|root,COG2865@2|Bacteria,4NEF5@976|Bacteroidetes,1HYUG@117743|Flavobacteriia	976|Bacteroidetes	K	PFAM Divergent AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
k59_1765372_1	323850.Shew_0271	2.01e-54	184.0	COG1075@1|root,COG1075@2|Bacteria,1NAEF@1224|Proteobacteria,1RZCX@1236|Gammaproteobacteria,2QB8G@267890|Shewanellaceae	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	plaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_1652239_1	1117315.AHCA01000006_gene2795	6.66e-57	181.0	2DPVN@1|root,32UMW@2|Bacteria,1N0TH@1224|Proteobacteria,1S98X@1236|Gammaproteobacteria,2Q39J@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Acyl-CoA cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_296338_1	1121931.AUHG01000010_gene70	2.84e-168	495.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_917196_1	1123514.KB905902_gene250	4.79e-90	267.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,460KY@72273|Thiotrichales	72273|Thiotrichales	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_917196_2	926560.KE387023_gene3850	1.69e-21	91.7	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574,ko:K12152	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_917196_3	1134474.O59_002974	3.85e-13	68.6	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1FID7@10|Cellvibrio	1236|Gammaproteobacteria	P	Citrate transporter	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_917200_2	94122.Shewana3_0062	4.01e-29	110.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,2QDB7@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1652242_1	1484460.JSWG01000009_gene130	2.49e-136	404.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,4PKJ5@976|Bacteroidetes,1HY50@117743|Flavobacteriia	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_1030626_1	572480.Arnit_1241	2.13e-10	60.1	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,42M05@68525|delta/epsilon subdivisions,2YNMZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_1030626_3	572480.Arnit_1243	4.01e-35	129.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_296359_1	1178825.ALIH01000016_gene616	1.05e-75	249.0	COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_70816_1	1197477.IA57_09050	3.69e-135	389.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_183918_1	1123514.KB905899_gene942	8.27e-125	374.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,45ZZJ@72273|Thiotrichales	72273|Thiotrichales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_183918_2	1123514.KB905899_gene943	3.42e-71	225.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,4610Y@72273|Thiotrichales	72273|Thiotrichales	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k59_183918_3	1123517.JOMR01000001_gene1018	5.87e-55	176.0	COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,463KP@72273|Thiotrichales	72273|Thiotrichales	T	Universal stress protein family	-	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
k59_183918_4	717772.THIAE_04110	2.4e-29	114.0	2CJI1@1|root,33SDY@2|Bacteria,1NTQD@1224|Proteobacteria,1SJW7@1236|Gammaproteobacteria,461M4@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_521993_1	1051646.VITU9109_26145	5.1e-10	63.5	COG0642@1|root,COG0745@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,1T1Y4@1236|Gammaproteobacteria,1XTDR@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	chiS	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,Response_reg
k59_13170_1	317936.Nos7107_5070	1.69e-22	91.3	COG2076@1|root,COG2076@2|Bacteria,1G9SH@1117|Cyanobacteria,1HP9J@1161|Nostocales	1117|Cyanobacteria	U	PFAM small multidrug resistance protein	-	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
k59_13170_2	1217720.ALOX01000011_gene2499	6.66e-21	92.4	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2TS08@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70822_1	1165841.SULAR_06673	3.72e-92	283.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2YMC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_747796_1	944547.ABLL_0639	4.28e-109	330.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1596129_2	563040.Saut_0242	3.31e-39	137.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspC2	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1596129_3	326298.Suden_0280	8.7e-99	290.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2YP63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_466239_1	1150621.SMUL_3043	3.64e-21	92.8	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2YNJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA binding S1 domain protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_917230_1	323850.Shew_1459	9.04e-10	56.6	2CH1F@1|root,2ZDFE@2|Bacteria,1QDK3@1224|Proteobacteria,1T9MY@1236|Gammaproteobacteria,2QC5P@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_917230_2	998088.B565_2032	2.14e-18	84.0	COG3633@1|root,COG3633@2|Bacteria,1MXE1@1224|Proteobacteria,1RP9B@1236|Gammaproteobacteria,1Y3F0@135624|Aeromonadales	135624|Aeromonadales	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
k59_635587_2	1121931.AUHG01000011_gene2297	1.29e-104	324.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_1086086_1	411154.GFO_2976	2.67e-08	53.9	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_1086086_2	411154.GFO_2975	9.39e-100	309.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_466252_1	1188252.AJYK01000065_gene2585	1.59e-28	120.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,1RNRS@1236|Gammaproteobacteria,1XSZF@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008683,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k59_1142774_1	497321.C664_09385	6.16e-15	74.3	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUM4@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1142774_2	497321.C664_12975	8.3e-32	122.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,2KUT0@206389|Rhodocyclales	206389|Rhodocyclales	M	3-Deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k59_352117_1	1250005.PHEL85_3158	1.99e-06	50.1	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,3VWJ7@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_352117_2	1121012.AUKX01000021_gene1672	4.32e-129	384.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia,23G8X@178469|Arenibacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_466259_1	1123228.AUIH01000002_gene1458	3.53e-22	90.9	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,1XMR5@135619|Oceanospirillales	135619|Oceanospirillales	O	Protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_1142785_2	709032.Sulku_1640	2.09e-52	172.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,42V0V@68525|delta/epsilon subdivisions,2YS63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_1142787_2	85643.Tmz1t_2371	3.1e-63	205.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VIFH@28216|Betaproteobacteria,2KX72@206389|Rhodocyclales	206389|Rhodocyclales	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_635640_1	1120966.AUBU01000006_gene3401	3.4e-65	204.0	2ECG8@1|root,336EJ@2|Bacteria,4NW0Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_635640_2	1189620.AJXL01000020_gene1561	0.000375	40.4	2E6UP@1|root,331EC@2|Bacteria,4NUYV@976|Bacteroidetes,1I59A@117743|Flavobacteriia,2NX3Q@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_917282_1	1121931.AUHG01000018_gene1394	1.47e-128	372.0	COG1295@1|root,COG1295@2|Bacteria,4NH9D@976|Bacteroidetes,1I0V2@117743|Flavobacteriia	976|Bacteroidetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_352151_1	1121931.AUHG01000010_gene423	1e-50	168.0	28JBH@1|root,2Z967@2|Bacteria,4NNHF@976|Bacteroidetes,1HYEA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
k59_352151_2	411154.GFO_3443	1.22e-103	308.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia	976|Bacteroidetes	E	cystathionine	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
k59_579063_1	411154.GFO_1513	2.47e-149	431.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	sad	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1596195_1	1121931.AUHG01000011_gene2430	4.79e-159	487.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_747867_1	1172190.M947_01630	4.42e-65	208.0	COG1376@1|root,COG1376@2|Bacteria,1RAMJ@1224|Proteobacteria,42Y3G@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1765488_1	317025.Tcr_0923	0.00012	43.1	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,45ZSM@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1765488_2	323848.Nmul_A1884	5.53e-36	129.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3731S@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_466310_1	1137281.D778_00748	1.02e-27	108.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1HWRB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_466310_2	1380600.AUYN01000009_gene1309	1.11e-37	128.0	2DP5F@1|root,330KU@2|Bacteria,4NV42@976|Bacteroidetes,1I5KT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_466310_3	1380600.AUYN01000009_gene1310	2.11e-82	246.0	COG1595@1|root,COG1595@2|Bacteria,4NHNI@976|Bacteroidetes,1HY4K@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_579073_1	323850.Shew_0540	4.53e-17	78.6	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1S1Z5@1236|Gammaproteobacteria,2Q9AV@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_1538290_1	391603.FBALC1_00672	2.07e-40	145.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
k59_354144_1	411154.GFO_0196	7.58e-117	337.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_354144_2	1121931.AUHG01000010_gene850	8.05e-40	142.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1767507_2	1042376.AFPK01000029_gene1513	1.47e-11	65.9	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia,406UC@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1710814_1	1249997.JHZW01000002_gene695	5.32e-103	303.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1HWZN@117743|Flavobacteriia,2PGHA@252356|Maribacter	976|Bacteroidetes	J	Ribosomal L25p family	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_1710814_2	1122225.AULQ01000005_gene2541	4.76e-88	263.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_694695_1	1172190.M947_01820	1.49e-109	324.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1RD7I@1224|Proteobacteria,42SM8@68525|delta/epsilon subdivisions,2YPEY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_973510_1	411154.GFO_2760	1.21e-10	60.8	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_973510_2	1121931.AUHG01000011_gene1763	3.24e-70	223.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,1HYJ7@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
k59_242429_1	945713.IALB_2164	1.56e-63	204.0	COG1284@1|root,COG1284@2|Bacteria	2|Bacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_749791_1	1123514.KB905901_gene50	2.23e-96	285.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_1032662_1	504487.JCM19302_4008	1.22e-90	282.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1HYRD@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_354158_1	1249975.JQLP01000001_gene3101	1.89e-109	333.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia,2P632@244698|Gillisia	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1316013_1	717231.Flexsi_1014	3.03e-147	426.0	COG1593@1|root,COG1593@2|Bacteria,2GFBZ@200930|Deferribacteres	200930|Deferribacteres	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_919178_1	62928.azo3161	3.57e-29	111.0	COG3642@1|root,COG3642@2|Bacteria,1N21R@1224|Proteobacteria,2WGQJ@28216|Betaproteobacteria,2KYS0@206389|Rhodocyclales	206389|Rhodocyclales	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_140596_16	1329250.WOSG25_180370	1.19e-09	59.3	2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,4HR69@91061|Bacilli	91061|Bacilli	S	YopX protein	-	-	-	-	-	-	-	-	-	-	-	-	YopX
k59_761921_1	572480.Arnit_1262	1.42e-103	305.0	COG0583@1|root,COG0583@2|Bacteria,1N8HZ@1224|Proteobacteria,43AFV@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	gltR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_983449_1	929558.SMGD1_1701	8.57e-78	236.0	2BS7I@1|root,30SN1@2|Bacteria,1Q8VY@1224|Proteobacteria,42VZW@68525|delta/epsilon subdivisions,2YQMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_983449_2	1537915.JU57_11210	2.69e-16	75.5	2AI7Y@1|root,318NF@2|Bacteria,1Q0NR@1224|Proteobacteria,42SAU@68525|delta/epsilon subdivisions,2YPMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1723234_1	1168067.JAGP01000001_gene460	1.56e-86	264.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,1RNKV@1236|Gammaproteobacteria,461DQ@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k59_1439617_1	1249975.JQLP01000003_gene185	1.19e-42	150.0	COG0463@1|root,COG0463@2|Bacteria,4PNQC@976|Bacteroidetes,1IMJ1@117743|Flavobacteriia,2P7BA@244698|Gillisia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1045035_1	572480.Arnit_0160	1.36e-143	414.0	COG0642@1|root,COG0642@2|Bacteria,1QZF0@1224|Proteobacteria,43CI9@68525|delta/epsilon subdivisions,2YTCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1045041_1	694427.Palpr_2928	1.76e-13	74.3	COG5557@1|root,COG5557@2|Bacteria,4NF8T@976|Bacteroidetes,2FW4G@200643|Bacteroidia	976|Bacteroidetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_931298_1	1380600.AUYN01000009_gene1198	6.69e-53	176.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1HXJC@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_931298_2	1380600.AUYN01000009_gene1197	7.67e-104	329.0	COG0460@1|root,COG0527@1|root,COG2021@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,COG2021@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Abhydrolase_1,Homoserine_dh,NAD_binding_3
k59_931302_1	1123514.KB905903_gene342	1.6e-32	123.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,45ZZU@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_931302_2	156889.Mmc1_3659	5.47e-26	106.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_983509_1	36874.HQ34_06920	5.46e-150	438.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes,2FNIZ@200643|Bacteroidia,22W7S@171551|Porphyromonadaceae	976|Bacteroidetes	G	Nucleoside permease	nupG	-	-	ko:K03289,ko:K11537	-	-	-	-	ko00000,ko02000	2.A.1.10.1,2.A.1.10.2	-	-	Nuc_H_symport
k59_983509_2	1319815.HMPREF0202_01955	1.25e-46	164.0	COG0402@1|root,COG0402@2|Bacteria,378PM@32066|Fusobacteria	32066|Fusobacteria	F	Psort location Cytoplasmic, score 9.97	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_198531_1	1123518.ARWI01000001_gene1351	1.97e-147	445.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_423925_1	1380600.AUYN01000009_gene2038	2.73e-130	387.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1206339_1	767817.Desgi_2040	3.34e-60	212.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
k59_423928_1	411154.GFO_0200	3.96e-168	483.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HWPI@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_366418_1	1380600.AUYN01000006_gene602	5.19e-150	434.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_140686_1	1121931.AUHG01000012_gene2869	4.24e-53	177.0	COG5183@1|root,COG5183@2|Bacteria,4NR0S@976|Bacteroidetes,1I34T@117743|Flavobacteriia	976|Bacteroidetes	A	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
k59_820429_1	572480.Arnit_0095	2.15e-13	67.8	COG1280@1|root,COG1280@2|Bacteria,1RET0@1224|Proteobacteria,42TQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_820429_2	944547.ABLL_0083	1.84e-43	145.0	COG0824@1|root,COG0824@2|Bacteria,1MZFI@1224|Proteobacteria,43AU9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Thioesterase-like superfamily	MA20_08165	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
k59_1666838_1	317025.Tcr_1702	1.41e-12	65.5	COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,1S7XG@1236|Gammaproteobacteria,461E2@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
k59_931330_1	563040.Saut_1031	1.41e-27	107.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_931330_2	563040.Saut_1038	4.78e-57	185.0	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,430TX@68525|delta/epsilon subdivisions,2YS1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
k59_1270756_1	944547.ABLL_1050	5.54e-39	132.0	COG2371@1|root,COG2371@2|Bacteria,1Q9AZ@1224|Proteobacteria,434A6@68525|delta/epsilon subdivisions,2YRYD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	-	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C
k59_1270756_2	572480.Arnit_1073	4.46e-79	239.0	COG0830@1|root,COG0830@2|Bacteria,1NIBD@1224|Proteobacteria,42Y30@68525|delta/epsilon subdivisions,2YR6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	UreF	-	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
k59_481089_1	1121931.AUHG01000010_gene718	3.14e-36	133.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia	976|Bacteroidetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_27210_1	1178825.ALIH01000015_gene1891	7.16e-133	402.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_27210_2	1380600.AUYN01000001_gene2320	1e-72	221.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1I28N@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_1100588_1	1172190.M947_07495	3.14e-47	168.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YNHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1100588_2	929558.SMGD1_1003	5.13e-06	48.1	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2YMJJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	malic enzyme	mez	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_1552457_1	572480.Arnit_1773	4.29e-109	317.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2YMCU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_1552457_2	572480.Arnit_1774	1.71e-11	63.9	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1611660_1	1232410.KI421418_gene2256	3.57e-53	179.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,43TTV@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
k59_198593_2	1296415.JACC01000034_gene1276	3.83e-38	141.0	COG2207@1|root,COG2207@2|Bacteria,4NKKA@976|Bacteroidetes,1HX54@117743|Flavobacteriia,2YHTZ@290174|Aquimarina	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1723359_1	504487.JCM19302_3781	8.76e-77	237.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1HWQ7@117743|Flavobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_1723359_2	313595.P700755_001864	3.6e-244	677.0	COG0270@1|root,COG0789@1|root,COG0270@2|Bacteria,COG0789@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia	976|Bacteroidetes	H	cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_17,MerR,MerR_1
k59_1723359_3	1392490.JHZX01000001_gene1387	6.32e-113	332.0	2CJP6@1|root,2Z7MS@2|Bacteria,4NJDB@976|Bacteroidetes,1I0M2@117743|Flavobacteriia	976|Bacteroidetes	L	Eco47II restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_Eco47II
k59_1723359_4	1137281.D778_01584	5.69e-56	177.0	COG3727@1|root,COG3727@2|Bacteria,4NQEH@976|Bacteroidetes,1I1D1@117743|Flavobacteriia	976|Bacteroidetes	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
k59_1611672_1	398720.MED217_00595	2.46e-49	174.0	2DBXW@1|root,2ZBRY@2|Bacteria,4NM6W@976|Bacteroidetes,1HYMB@117743|Flavobacteriia,2XJY0@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017
k59_1439755_1	1380600.AUYN01000009_gene1195	7.86e-21	90.5	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1439755_2	1380600.AUYN01000009_gene1194	2.46e-112	332.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1HX9B@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_650202_1	1042376.AFPK01000018_gene1678	4.89e-147	447.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,1IG81@117743|Flavobacteriia,406SK@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N,Plug
k59_650202_2	1392490.JHZX01000001_gene2801	2.72e-54	174.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,1I213@117743|Flavobacteriia	976|Bacteroidetes	S	Bacteriocin-protection protein	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
k59_1497803_1	572480.Arnit_0656	1.61e-09	55.1	2E94U@1|root,333DN@2|Bacteria,1P6X3@1224|Proteobacteria,42TTX@68525|delta/epsilon subdivisions,2YPST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1497803_2	572480.Arnit_0657	1.04e-92	292.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1382844_1	1178825.ALIH01000016_gene604	9.19e-88	279.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1382844_2	746697.Aeqsu_2657	2.27e-66	209.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1HXP9@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1045139_1	207954.MED92_06263	7.69e-71	244.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T245@1236|Gammaproteobacteria,1XJ38@135619|Oceanospirillales	135619|Oceanospirillales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1439765_1	1172190.M947_00655	5.22e-18	77.8	2BSN9@1|root,32MQW@2|Bacteria,1Q3CP@1224|Proteobacteria,42X3U@68525|delta/epsilon subdivisions,2YQYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AF0941-like	-	-	-	-	-	-	-	-	-	-	-	-	AF0941-like
k59_1439765_2	1172190.M947_09400	2.02e-98	292.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_536871_2	387093.SUN_1064	1.41e-56	189.0	29Y2F@1|root,30JVD@2|Bacteria,1RAWX@1224|Proteobacteria,4300B@68525|delta/epsilon subdivisions,2YRWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_368504_2	572480.Arnit_2578	1.02e-55	186.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1046940_1	1380600.AUYN01000006_gene289	9.88e-146	429.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1HXSX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_1046940_2	1123037.AUDE01000022_gene1474	8.8e-28	111.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_87463_1	1406840.Q763_09680	2.24e-45	147.0	COG4319@1|root,COG4319@2|Bacteria,4NQ7F@976|Bacteroidetes	976|Bacteroidetes	S	CbbQ NirQ NorQ GpvN family protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_87463_2	1406840.Q763_09685	6.51e-154	432.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k59_87463_3	1406840.Q763_09690	1.56e-130	370.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1I1AG@117743|Flavobacteriia,2NU4Y@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
k59_87463_4	1406840.Q763_09695	5.18e-53	167.0	COG0662@1|root,COG0662@2|Bacteria,4NVRF@976|Bacteroidetes,1I5QV@117743|Flavobacteriia,2NZHD@237|Flavobacterium	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_142756_1	929558.SMGD1_0735	1.84e-117	341.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,42MG5@68525|delta/epsilon subdivisions,2YN7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_142756_2	929558.SMGD1_0734	1.84e-27	104.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42QYK@68525|delta/epsilon subdivisions,2YNZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ABC transporter, ATP-binding protein	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k59_538831_1	945713.IALB_2002	9.51e-31	117.0	COG1087@1|root,COG1087@2|Bacteria	2|Bacteria	M	UDP-glucose 4-epimerase activity	galE	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_538831_2	1191523.MROS_2445	6.66e-46	157.0	COG1703@1|root,COG1703@2|Bacteria	2|Bacteria	E	isobutyryl-CoA mutase activity	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_1272762_1	68570.DC74_1782	5.23e-23	98.2	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
k59_1499845_1	1121931.AUHG01000011_gene1966	4.27e-95	288.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_1384884_1	944547.ABLL_1812	2.75e-69	211.0	COG1433@1|root,COG1433@2|Bacteria,1P8Y4@1224|Proteobacteria,42VVM@68525|delta/epsilon subdivisions,2YQI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1499850_1	411154.GFO_2741	4.5e-34	128.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1HY1F@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
k59_1499850_2	411154.GFO_2743	1.83e-190	529.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,1HYU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
k59_1499850_3	411154.GFO_2744	1.15e-24	96.3	COG1430@1|root,COG1430@2|Bacteria,4NQ5G@976|Bacteroidetes,1I2TF@117743|Flavobacteriia	976|Bacteroidetes	S	acr, cog1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
k59_200606_1	326298.Suden_0720	6.06e-139	402.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_200606_2	563040.Saut_0738	8.66e-39	144.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_1159326_1	411154.GFO_2778	1.13e-117	338.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_313230_1	929558.SMGD1_1833	4.96e-135	392.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,42NRP@68525|delta/epsilon subdivisions,2YN5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipopolysaccharide heptosyltransferase	waaC	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_1272802_1	1137281.D778_00058	5.51e-05	44.3	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_1272802_2	1121898.Q766_16595	9.15e-06	47.4	COG0526@1|root,COG0526@2|Bacteria,4NT1R@976|Bacteroidetes,1I4MU@117743|Flavobacteriia,2NWK3@237|Flavobacterium	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_1725375_1	323850.Shew_1760	1.09e-53	189.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,2Q8H4@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_216621_1	929558.SMGD1_0802	2.17e-169	485.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2YMV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_1220962_1	1121011.AUCB01000050_gene1410	3.41e-08	54.3	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,23HR7@178469|Arenibacter	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_1220962_2	595460.RRSWK_00731	2.71e-70	238.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_1516247_1	1380600.AUYN01000009_gene1734	7.01e-38	135.0	COG3712@1|root,COG3712@2|Bacteria,4NH8I@976|Bacteroidetes,1HXP7@117743|Flavobacteriia	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_1516247_2	1178825.ALIH01000001_gene2629	3.39e-101	295.0	COG1595@1|root,COG1595@2|Bacteria,4NMCX@976|Bacteroidetes,1I1EN@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1516247_3	1178825.ALIH01000001_gene2630	8.29e-217	616.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1570110_1	1168067.JAGP01000001_gene1370	1.37e-134	389.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,4600G@72273|Thiotrichales	72273|Thiotrichales	P	transporter, permease	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_1570110_2	1123514.KB905899_gene1271	4.8e-186	526.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,45ZQ1@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_668713_1	1123518.ARWI01000001_gene1440	1.26e-107	320.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_1456950_1	411154.GFO_2812	2.38e-110	325.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_329385_1	563040.Saut_0681	1.02e-20	87.0	29QY9@1|root,30BZ3@2|Bacteria,1QTGR@1224|Proteobacteria,42VBX@68525|delta/epsilon subdivisions,2YQ83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_329385_2	929558.SMGD1_2156	1.74e-37	132.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2YNGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_608869_1	1121931.AUHG01000011_gene1633	3.61e-34	126.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1IJXK@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_608869_2	1121931.AUHG01000011_gene1632	1.79e-94	290.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_271682_1	90814.KL370891_gene429	7.97e-110	335.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4602V@72273|Thiotrichales	72273|Thiotrichales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_668726_1	1266925.JHVX01000005_gene1997	2.31e-12	66.2	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VHWW@28216|Betaproteobacteria,371SC@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k59_668726_2	1288494.EBAPG3_29660	2.47e-54	181.0	2DKYH@1|root,30WKQ@2|Bacteria,1RCXC@1224|Proteobacteria,2VR6P@28216|Betaproteobacteria,372XE@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
k59_1626810_1	1565129.JSFF01000026_gene1265	4.94e-49	162.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,2Q9B8@267890|Shewanellaceae	1236|Gammaproteobacteria	H	PFAM D12 class N6 adenine-specific DNA methyltransferase	dam	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k59_780325_1	1565129.JSFF01000001_gene820	7.2e-144	414.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,2QB31@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_780325_2	425104.Ssed_3415	2.5e-62	203.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,2Q8TX@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
k59_836668_1	1216932.CM240_1740	1.49e-12	69.7	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,36F9I@31979|Clostridiaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_1001673_1	326298.Suden_1330	5.22e-95	284.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2YMSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iIT341.HP0961	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1685049_1	768671.ThimaDRAFT_4265	9.29e-08	52.8	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1WXMH@135613|Chromatiales	135613|Chromatiales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_1685049_2	1123228.AUIH01000009_gene1977	5.5e-29	105.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1XKYP@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_946454_2	929558.SMGD1_0817	9.01e-21	89.7	COG4968@1|root,COG4968@2|Bacteria,1QUIY@1224|Proteobacteria,42S53@68525|delta/epsilon subdivisions,2YPC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1798768_1	1565129.JSFF01000008_gene2626	1.8e-99	294.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1S3MJ@1236|Gammaproteobacteria,2QB1P@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_780362_1	425104.Ssed_2618	4.9e-97	289.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,2QA79@267890|Shewanellaceae	1236|Gammaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_2618	dCMP_cyt_deam_1,dCMP_cyt_deam_2
k59_158182_1	929558.SMGD1_0877	8.05e-76	244.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_946474_1	1249997.JHZW01000003_gene2332	9.08e-103	308.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HYW2@117743|Flavobacteriia,2PHTV@252356|Maribacter	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_1001704_1	1121887.AUDK01000017_gene58	3.15e-152	439.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia,2NUVR@237|Flavobacterium	976|Bacteroidetes	G	Pfam Major Facilitator Superfamily	gluP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_836693_1	992406.RIA_1704	5.3e-113	339.0	COG0433@1|root,COG0433@2|Bacteria,4NGNM@976|Bacteroidetes,1HZRS@117743|Flavobacteriia	976|Bacteroidetes	S	COG0433 Predicted ATPase	-	-	-	ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,DndE,FtsK_SpoIIIE
k59_727345_1	1380600.AUYN01000006_gene300	7.46e-69	228.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia	976|Bacteroidetes	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
k59_1457017_1	504487.JCM19302_4015	7.53e-214	597.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_1001723_1	1395587.P364_0110300	7.96e-13	68.9	COG1846@1|root,COG1846@2|Bacteria,1VEGV@1239|Firmicutes,4HQ4V@91061|Bacilli,26ZAF@186822|Paenibacillaceae	91061|Bacilli	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_1061461_1	572480.Arnit_2918	1.13e-103	313.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1457020_1	929558.SMGD1_0735	1.54e-50	166.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,42MG5@68525|delta/epsilon subdivisions,2YN7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_1457020_2	1537917.JU82_03665	2.93e-07	53.1	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1221052_1	1380600.AUYN01000009_gene1026	3.66e-162	478.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1001727_1	1173264.KI913949_gene1979	8.12e-24	97.4	COG3415@1|root,COG3415@2|Bacteria,1G6I1@1117|Cyanobacteria,1HHG5@1150|Oscillatoriales	1117|Cyanobacteria	L	Winged helix-turn helix	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_32,HTH_33
k59_608937_1	313606.M23134_06172	0.000183	47.4	COG4733@1|root,COG4733@2|Bacteria,4PMD6@976|Bacteroidetes,47UPT@768503|Cytophagia	976|Bacteroidetes	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
k59_216715_1	1123228.AUIH01000012_gene33	5.21e-83	257.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,1RMRY@1236|Gammaproteobacteria,1XIED@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_1457026_1	1380600.AUYN01000007_gene3163	4.44e-147	436.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_727371_1	1168067.JAGP01000001_gene1727	2.64e-109	330.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,45ZMK@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_216723_1	746697.Aeqsu_3069	2.72e-56	189.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1HZDU@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_553060_1	563040.Saut_0573	1.42e-87	271.0	COG1776@1|root,COG1776@2|Bacteria,1RICK@1224|Proteobacteria,42NMU@68525|delta/epsilon subdivisions,2YMV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k59_384456_1	411154.GFO_1547	9.22e-105	312.0	COG0834@1|root,COG0834@2|Bacteria,4NEQQ@976|Bacteroidetes,1I027@117743|Flavobacteriia	976|Bacteroidetes	ET	Ligand-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Lig_chan,SBP_bac_3
k59_668818_1	572480.Arnit_1083	2.18e-109	322.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2YMGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1685123_1	1380600.AUYN01000009_gene1294	2.46e-129	390.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
k59_946517_1	1123518.ARWI01000001_gene2205	2.5e-64	204.0	COG1639@1|root,COG1639@2|Bacteria,1R4P9@1224|Proteobacteria,1RRBF@1236|Gammaproteobacteria,463MU@72273|Thiotrichales	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_329507_1	1380384.JADN01000003_gene475	2.47e-57	183.0	COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,1I246@117743|Flavobacteriia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
k59_727405_1	2903.EOD41712	1.81e-07	55.1	COG2730@1|root,2RFQF@2759|Eukaryota	2759|Eukaryota	G	Carbohydrate binding domain X2	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_1,CBM_X2,Cellulase
k59_727405_2	1297857.CAUK01000004_gene1551	3.05e-16	77.8	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_3,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_106974_2	700598.Niako_4587	1e-29	116.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1IPVT@117747|Sphingobacteriia	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_1572818_1	411154.GFO_3374	9.8e-63	204.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_1572818_2	1123234.AUKI01000002_gene1800	6.29e-27	107.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_106976_1	335543.Sfum_3699	2.73e-58	200.0	COG1629@1|root,COG4771@2|Bacteria,1MXY7@1224|Proteobacteria,42MSN@68525|delta/epsilon subdivisions,2WIK9@28221|Deltaproteobacteria,2MQ6R@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_949070_1	1178825.ALIH01000011_gene8	4.89e-77	238.0	2F30U@1|root,33VW3@2|Bacteria,4P3R3@976|Bacteroidetes,1I8ZN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1745019_1	1565129.JSFF01000002_gene3454	3.43e-116	344.0	COG1301@1|root,COG1301@2|Bacteria,1P4W9@1224|Proteobacteria,1S0UN@1236|Gammaproteobacteria,2Q9PI@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_107005_1	1172190.M947_02945	1.48e-72	230.0	29W5U@1|root,30HQY@2|Bacteria,1QUJN@1224|Proteobacteria,42NUV@68525|delta/epsilon subdivisions,2YNFP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1178700_1	1172190.M947_08300	9.47e-48	156.0	2AK71@1|root,31AX6@2|Bacteria,1Q6EC@1224|Proteobacteria,432ZM@68525|delta/epsilon subdivisions,2YSGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1178700_2	929558.SMGD1_1062	1.25e-74	231.0	COG0492@1|root,COG0492@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2YMV2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	pyridine nucleotide-disulfide oxidoreductase	trxB_2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	FixS,Pyr_redox_3
k59_219721_1	1249975.JQLP01000008_gene380	3.88e-90	273.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia,2P5D6@244698|Gillisia	976|Bacteroidetes	HP	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_46858_1	1121931.AUHG01000011_gene2120	2.68e-80	249.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
k59_46858_2	985255.APHJ01000039_gene202	8.85e-13	67.4	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1HXUW@117743|Flavobacteriia,2P5N2@244698|Gillisia	976|Bacteroidetes	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_1688150_1	1137281.D778_01270	1.99e-45	153.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_611716_1	572480.Arnit_0410	7.76e-127	372.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_107045_1	1123514.KB905899_gene1320	1.27e-103	306.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,460CZ@72273|Thiotrichales	72273|Thiotrichales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1350821_1	572480.Arnit_2084	2.36e-129	372.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_387618_1	1120953.AUBH01000004_gene3017	1.37e-33	131.0	COG2199@1|root,COG3447@1|root,COG3447@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRYD@1236|Gammaproteobacteria,46CH6@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
k59_387636_1	411154.GFO_2625	4.89e-89	287.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
k59_219762_1	317025.Tcr_1053	6.03e-54	180.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,460F1@72273|Thiotrichales	72273|Thiotrichales	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k59_332667_1	563040.Saut_0077	1.82e-72	234.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_730535_1	717773.Thicy_0241	3.68e-153	469.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1519635_1	313603.FB2170_13071	7.43e-06	45.8	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_1519635_2	1380384.JADN01000008_gene1040	2e-77	233.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_1178809_1	1328313.DS2_15019	3.33e-13	75.5	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,46D5V@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_219812_1	323850.Shew_1473	1.44e-51	170.0	COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,2Q9FK@267890|Shewanellaceae	1236|Gammaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	SO2179	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PTPS
k59_219812_2	211586.SO_2180	5.2e-41	144.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria,2Q9HR@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M23B	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1178822_1	572480.Arnit_1679	1.42e-113	344.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_1292000_1	1123033.ARNF01000087_gene1387	3.47e-50	181.0	COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,1RQH5@1236|Gammaproteobacteria,3NKDP@468|Moraxellaceae	1236|Gammaproteobacteria	L	CRISPR-associated helicase, Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
k59_107136_1	1178825.ALIH01000005_gene274	3.01e-64	197.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1I2UN@117743|Flavobacteriia	976|Bacteroidetes	J	tRNA-binding protein	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
k59_107136_2	1347342.BN863_10890	6.82e-67	205.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1I2S7@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
k59_1224476_1	90813.JQMT01000001_gene1443	7.49e-59	197.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,45ZQ0@72273|Thiotrichales	72273|Thiotrichales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_1064581_1	1168067.JAGP01000001_gene2078	3.56e-108	324.0	COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1292018_1	1237149.C900_04675	2.9e-101	323.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,47JXH@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1178843_1	990073.ATHU01000001_gene1797	9.51e-52	166.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,42VM2@68525|delta/epsilon subdivisions,2YQCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k59_1178843_2	1249480.B649_06975	3.99e-62	192.0	2E67S@1|root,32Q79@2|Bacteria,1N05A@1224|Proteobacteria,42X30@68525|delta/epsilon subdivisions,2YQVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein NifW	-	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_672012_1	1380600.AUYN01000006_gene648	5.34e-50	178.0	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_783884_1	1347342.BN863_19790	3.11e-134	386.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
k59_783884_2	1347342.BN863_19780	7.05e-266	743.0	COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	ybbD	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_1292033_1	1380600.AUYN01000010_gene866	2.3e-75	246.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1125659_1	1392489.JPOL01000002_gene1283	2.99e-42	156.0	COG4733@1|root,COG4733@2|Bacteria,4PNDB@976|Bacteroidetes,1HZQB@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,DUF4990
k59_1125659_2	1492738.FEM21_10270	6.88e-73	256.0	COG3866@1|root,COG4677@1|root,COG4935@1|root,COG5263@1|root,COG5492@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,COG4935@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,4NHZ1@976|Bacteroidetes,1IJTK@117743|Flavobacteriia,2NTRH@237|Flavobacterium	976|Bacteroidetes	G	pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
k59_1523230_1	572480.Arnit_2631	6.1e-121	356.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1523230_2	572480.Arnit_2630	7.88e-35	131.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_899252_1	1049564.TevJSym_ac00850	2.22e-24	103.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1J56M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440	Ala_racemase_C,Ala_racemase_N
k59_899252_2	545276.KB898727_gene294	2.77e-20	89.7	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_1630789_1	709032.Sulku_1859	2.2e-31	119.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42QNP@68525|delta/epsilon subdivisions,2YR5C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1630789_2	945550.VISI1226_11701	1.08e-23	102.0	COG2244@1|root,COG2244@2|Bacteria,1R6GF@1224|Proteobacteria,1RZZ6@1236|Gammaproteobacteria,1XVIC@135623|Vibrionales	135623|Vibrionales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_336345_1	1214166.ALLG01000009_gene535	1.09e-20	97.4	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,1WT1P@1307|Streptococcus suis	91061|Bacilli	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_1182405_1	1122918.KB907250_gene3582	6.27e-62	201.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,4HBYA@91061|Bacilli,277A8@186822|Paenibacillaceae	91061|Bacilli	G	Arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
k59_734122_1	563040.Saut_0739	9.03e-15	73.2	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2YMD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_734122_2	326298.Suden_0721	2.83e-72	227.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2YMD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	2-nitropropane dioxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_336356_1	929558.SMGD1_0137	5.68e-31	119.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2YMG2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_336356_2	1172190.M947_09270	1.08e-59	191.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2YMV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0400	LYTB
k59_1067919_1	1121931.AUHG01000015_gene1201	1.19e-180	534.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_1691902_1	572480.Arnit_3137	6.31e-31	111.0	COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,43D4D@68525|delta/epsilon subdivisions,2YTGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
k59_1691902_2	572480.Arnit_3138	1.64e-92	273.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,42RSP@68525|delta/epsilon subdivisions,2YPDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_1691902_3	572480.Arnit_3139	2.56e-32	119.0	COG3658@1|root,COG3658@2|Bacteria,1REFV@1224|Proteobacteria,42Q0G@68525|delta/epsilon subdivisions,2YN98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
k59_1008659_1	90814.KL370891_gene254	1.5e-115	342.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1630847_1	32024.JMTI01000008_gene1222	6.04e-78	245.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_336430_1	1167006.UWK_03191	3.07e-13	65.1	2EIMJ@1|root,33CCU@2|Bacteria,1NMXZ@1224|Proteobacteria,433IY@68525|delta/epsilon subdivisions,2WY9B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_277405_1	1123518.ARWI01000001_gene1466	6.94e-48	162.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,460W9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
k59_1463483_1	1121931.AUHG01000011_gene2051	3.41e-121	369.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_223117_1	1353528.DT23_09705	3.9e-27	102.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,2U5P8@28211|Alphaproteobacteria,2XNE7@285107|Thioclava	28211|Alphaproteobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
k59_223117_2	1353528.DT23_09700	1.48e-44	147.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,2XMBR@285107|Thioclava	28211|Alphaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k59_1523373_1	756067.MicvaDRAFT_4044	4.7e-40	158.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k59_1406063_1	1007105.PT7_0495	5.1e-58	191.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2VNHE@28216|Betaproteobacteria,3T2T9@506|Alcaligenaceae	28216|Betaproteobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1576235_1	1232410.KI421424_gene1636	6.59e-121	356.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria,43TG3@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_391439_2	1250006.JHZZ01000001_gene2222	1.18e-75	251.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia,3VWZU@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_952168_1	1197477.IA57_01550	6.96e-51	166.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1HZJ6@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_952168_2	745718.JADT01000004_gene1260	6.92e-27	101.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1I18G@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_277435_1	90814.KL370891_gene1456	2.46e-52	183.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,461XY@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_391458_2	207954.MED92_17137	1.31e-41	159.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XHU8@135619|Oceanospirillales	135619|Oceanospirillales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_336479_1	1120970.AUBZ01000032_gene2555	1.32e-65	217.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,46645@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_1228234_1	929558.SMGD1_0366	1.25e-71	221.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2YN3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_1068025_1	338963.Pcar_3142	1.69e-71	233.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,43TPQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_734282_1	305700.B447_03588	1.57e-70	237.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1182584_1	1172190.M947_09410	8.33e-86	257.0	COG0212@1|root,COG0212@2|Bacteria,1RDZJ@1224|Proteobacteria,42SXM@68525|delta/epsilon subdivisions,2YPJD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_1182584_2	1172190.M947_09405	1.05e-101	312.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1748961_1	1250006.JHZZ01000001_gene2229	7.71e-107	321.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1463565_1	323850.Shew_1995	3.85e-103	305.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,2Q9ZK@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_448198_1	1178825.ALIH01000001_gene2570	2.78e-158	496.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2
k59_842210_1	519989.ECTPHS_10536	3.19e-20	91.7	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1WXDA@135613|Chromatiales	135613|Chromatiales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_842210_2	1168067.JAGP01000001_gene141	1.13e-71	228.0	COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RRA7@1236|Gammaproteobacteria,45ZRQ@72273|Thiotrichales	72273|Thiotrichales	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
k59_1694490_1	1190606.AJYG01000171_gene90	5.61e-30	121.0	COG1455@1|root,COG2200@1|root,COG1455@2|Bacteria,COG2200@2|Bacteria,1MXAG@1224|Proteobacteria,1RSMG@1236|Gammaproteobacteria,1Y0P5@135623|Vibrionales	135623|Vibrionales	GT	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PTS_EIIC
k59_225705_1	504487.JCM19302_3208	4.77e-147	420.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_1070611_1	929558.SMGD1_1835	4.64e-28	112.0	294BG@1|root,2ZRRP@2|Bacteria,1RG32@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,LPP20
k59_1185145_2	1121931.AUHG01000010_gene820	2.06e-94	286.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_1466365_1	411154.GFO_3422	4.93e-62	191.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1466365_2	411154.GFO_3421	7.33e-53	172.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_508076_1	929558.SMGD1_1651	1.79e-195	543.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2YMQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_508076_2	425400.LS65_08035	5.04e-15	74.7	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2YN5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_1070627_1	323850.Shew_1956	9.12e-16	72.4	COG3771@1|root,COG3771@2|Bacteria,1MZGX@1224|Proteobacteria,1S9X9@1236|Gammaproteobacteria,2QCJD@267890|Shewanellaceae	1236|Gammaproteobacteria	S	involved in the assembly of lipopolysaccharide (LPS)	lapA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1903509	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
k59_1070627_2	1565129.JSFF01000028_gene706	1.89e-104	311.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,2Q8I4@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_7,TPR_8
k59_1011485_2	675816.VIA_001162	1.17e-60	202.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,1T257@1236|Gammaproteobacteria,1Y33K@135623|Vibrionales	135623|Vibrionales	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,Response_reg
k59_1230855_1	572480.Arnit_0030	7.8e-88	260.0	COG2077@1|root,COG2077@2|Bacteria	2|Bacteria	O	thioredoxin peroxidase activity	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k59_1230855_2	572480.Arnit_0029	7.72e-08	52.4	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,42Z77@68525|delta/epsilon subdivisions,2YRAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_1298525_1	1537917.JU82_00660	1.85e-92	297.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2YNGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_790193_1	1250006.JHZZ01000001_gene1098	1.38e-40	150.0	COG1874@1|root,COG1874@2|Bacteria,4NE2P@976|Bacteroidetes,1HZBG@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom2,Glyco_hydro_35
k59_1466431_1	1232410.KI421421_gene3421	2.05e-11	63.9	2E1I6@1|root,32WW2@2|Bacteria,1NTI4@1224|Proteobacteria,42YDB@68525|delta/epsilon subdivisions,2WTNY@28221|Deltaproteobacteria,43TFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
k59_1466431_2	316067.Geob_2910	6.88e-45	157.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions,2WJW5@28221|Deltaproteobacteria,43UU9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_1466439_1	1121931.AUHG01000020_gene3160	5.06e-41	150.0	COG1345@1|root,COG1345@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia	976|Bacteroidetes	N	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1466439_2	655815.ZPR_1860	6.63e-23	89.4	2EEE6@1|root,33887@2|Bacteria,4NWWV@976|Bacteroidetes,1I572@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1466439_3	411154.GFO_1881	1.21e-79	241.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1I1ZP@117743|Flavobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
k59_1579136_1	980584.AFPB01000174_gene1562	6.8e-10	63.5	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia,406KS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_1579136_2	1380600.AUYN01000007_gene3260	4.88e-40	146.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_1230901_1	1380600.AUYN01000007_gene3394	1.2e-122	357.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_394202_1	1123514.KB905899_gene1877	1.13e-12	66.6	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,4622Q@72273|Thiotrichales	72273|Thiotrichales	GM	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_394202_2	1123514.KB905899_gene1876	1.56e-50	171.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,45ZYR@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_53030_1	865937.Gilli_2905	2.76e-10	58.2	2EG2H@1|root,339UG@2|Bacteria,4NXGG@976|Bacteroidetes,1I6AF@117743|Flavobacteriia,2P7QC@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_53030_2	411154.GFO_0357	1.97e-92	275.0	COG1573@1|root,COG1573@2|Bacteria,4NECP@976|Bacteroidetes,1HWXH@117743|Flavobacteriia	976|Bacteroidetes	L	DNA metabolism protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
k59_508201_1	929558.SMGD1_2643	2.22e-77	252.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_562515_1	929506.CbC4_1987	1.41e-31	127.0	COG2199@1|root,COG2203@1|root,COG3899@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
k59_790271_1	1123518.ARWI01000001_gene144	2.56e-81	250.0	COG3137@1|root,COG3137@2|Bacteria,1QSGG@1224|Proteobacteria,1RVWA@1236|Gammaproteobacteria,4624V@72273|Thiotrichales	72273|Thiotrichales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
k59_1230961_1	929558.SMGD1_0387	5.72e-32	114.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42RBS@68525|delta/epsilon subdivisions,2YTD0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_1230961_2	929558.SMGD1_0386	2.52e-45	165.0	COG0840@1|root,COG0840@2|Bacteria,1N5N4@1224|Proteobacteria,42RSG@68525|delta/epsilon subdivisions,2YRU6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_902374_1	326298.Suden_1815	7.53e-136	399.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_508215_1	1123514.KB905899_gene440	2.79e-87	270.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,45ZVI@72273|Thiotrichales	72273|Thiotrichales	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_562541_1	292415.Tbd_1416	2.84e-70	227.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,1KRD0@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_1298663_1	425104.Ssed_1911	2.43e-78	260.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,2QA9P@267890|Shewanellaceae	1236|Gammaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_53069_1	1250278.JQNQ01000001_gene2107	8.05e-134	382.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
k59_1231013_1	929558.SMGD1_0159	1.1e-81	251.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2YN18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_849241_1	929558.SMGD1_2226	1.12e-102	325.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1132370_1	1380600.AUYN01000006_gene802	8.42e-122	358.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1301977_1	563040.Saut_2073	4.95e-53	176.0	COG1672@1|root,COG1672@2|Bacteria,1PZGT@1224|Proteobacteria,42QN9@68525|delta/epsilon subdivisions,2YNKC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_1527634_1	1121931.AUHG01000010_gene572	1.36e-120	350.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_680567_1	326298.Suden_0728	4.17e-129	370.0	COG4123@1|root,COG4123@2|Bacteria,1RDSC@1224|Proteobacteria,42RIN@68525|delta/epsilon subdivisions,2YP8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_1584252_1	376686.Fjoh_4993	6.86e-08	53.1	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1I2CE@117743|Flavobacteriia,2NT1R@237|Flavobacterium	976|Bacteroidetes	GM	Histidinol phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1584252_2	1380600.AUYN01000001_gene2267	1.86e-49	159.0	2CJFR@1|root,32T3P@2|Bacteria,4NTID@976|Bacteroidetes,1I41R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1584252_3	504487.JCM19302_2506	3.2e-91	277.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_341139_1	929558.SMGD1_0813	7.71e-97	289.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2YPC0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_1075243_1	90814.KL370891_gene647	1.99e-48	166.0	COG0524@1|root,COG2146@1|root,COG0524@2|Bacteria,COG2146@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
k59_567438_1	1121931.AUHG01000017_gene1551	6.02e-74	226.0	COG3708@1|root,COG3708@2|Bacteria,4NQ46@976|Bacteroidetes,1I45F@117743|Flavobacteriia	976|Bacteroidetes	K	transcription activator, effector binding	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
k59_567438_3	1124780.ANNU01000073_gene702	1.46e-09	59.3	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NJ5G@976|Bacteroidetes,47MAH@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF302,TPR_2
k59_1019505_1	1392490.JHZX01000001_gene575	3.22e-39	133.0	COG2921@1|root,COG2921@2|Bacteria,4NSCF@976|Bacteroidetes,1I49D@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k59_1019505_2	1443665.JACA01000005_gene322	3.12e-71	220.0	COG3911@1|root,COG3911@2|Bacteria,4NNT6@976|Bacteroidetes,1I25D@117743|Flavobacteriia,2YIN5@290174|Aquimarina	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k59_1019505_3	983544.Lacal_2151	4.2e-80	255.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1HX0Y@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_1357854_1	1223410.KN050846_gene1094	2.76e-05	47.4	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Sortilin-Vps10
k59_1357854_2	313606.M23134_02095	7.39e-67	254.0	COG1649@1|root,COG3291@1|root,COG1649@2|Bacteria,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,47Y1M@768503|Cytophagia	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Sortilin-Vps10
k59_1075255_1	1197477.IA57_09615	1.02e-149	439.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_624079_2	1123518.ARWI01000001_gene113	1.01e-100	301.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,460AG@72273|Thiotrichales	72273|Thiotrichales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_1019523_1	1237149.C900_03151	1.13e-107	320.0	COG0205@1|root,COG0205@2|Bacteria,4NGN7@976|Bacteroidetes,47TRF@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_624086_1	1121931.AUHG01000010_gene81	1.8e-114	334.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1132423_1	305700.B447_17376	1.13e-102	312.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,2KU7K@206389|Rhodocyclales	206389|Rhodocyclales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1302047_1	94624.Bpet1942	3.38e-101	305.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,3T1Y2@506|Alcaligenaceae	28216|Betaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1527693_1	1349767.GJA_3586	1.73e-41	155.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
k59_793467_1	1165841.SULAR_07770	7.53e-155	453.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_793467_2	563040.Saut_1836	2.34e-29	115.0	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_906572_1	929558.SMGD1_1804	5.17e-73	231.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1414900_1	768671.ThimaDRAFT_3283	4.06e-20	89.7	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1WWVD@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_1414900_2	1123518.ARWI01000001_gene2434	6.91e-33	118.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,460RU@72273|Thiotrichales	72273|Thiotrichales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_793476_1	1236542.BALM01000017_gene1247	2.56e-81	271.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,2Q8WR@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_1697286_1	926559.JoomaDRAFT_2189	7.21e-192	552.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_567501_2	536233.CLO_2414	3.93e-07	59.7	2DU2B@1|root,33NMT@2|Bacteria,1W1YR@1239|Firmicutes,256Q4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1019576_1	1168067.JAGP01000001_gene568	6.51e-53	177.0	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_906588_1	90814.KL370891_gene429	1.16e-196	564.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4602V@72273|Thiotrichales	72273|Thiotrichales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1132457_1	1121912.AUHD01000007_gene485	2.37e-272	780.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_398192_1	1121931.AUHG01000010_gene799	3.11e-122	363.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1HZVU@117743|Flavobacteriia	976|Bacteroidetes	IQ	amp-binding	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_117375_1	411154.GFO_2975	1.83e-104	322.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
k59_1472689_1	1123518.ARWI01000001_gene681	5.5e-49	159.0	COG2020@1|root,COG2020@2|Bacteria,1NAP9@1224|Proteobacteria,1SZWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_1472689_2	90814.KL370891_gene630	2.07e-24	99.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,4606B@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_1134026_1	1168067.JAGP01000001_gene1638	2.01e-15	75.5	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,460TR@72273|Thiotrichales	72273|Thiotrichales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1134026_2	1168067.JAGP01000001_gene1639	3.89e-204	568.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria,460KV@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_1134026_3	90813.JQMT01000001_gene256	5.42e-51	162.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,460WX@72273|Thiotrichales	72273|Thiotrichales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_1134026_4	1168067.JAGP01000001_gene298	1.21e-141	414.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_851064_1	1353276.JADR01000002_gene2069	2.93e-139	416.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_851064_2	946077.W5A_07512	0.0	907.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HX4R@117743|Flavobacteriia	976|Bacteroidetes	P	arylsulfatase a	atsA_1	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
k59_738820_2	1123518.ARWI01000001_gene1091	4.52e-120	349.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,45ZP5@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_512333_1	411154.GFO_3515	1.33e-134	384.0	COG0702@1|root,COG0702@2|Bacteria,4NIXP@976|Bacteroidetes,1HZVX@117743|Flavobacteriia	976|Bacteroidetes	GM	Pfam NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k59_512333_2	1121912.AUHD01000003_gene2967	2.68e-28	112.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_795391_1	1121931.AUHG01000011_gene1821	1.47e-41	139.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
k59_795391_2	411154.GFO_2933	8.71e-26	104.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1359485_1	929558.SMGD1_1140	4.9e-118	351.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YNK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_682662_1	1380600.AUYN01000003_gene48	6.4e-127	382.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_1304071_1	1289387.AUKW01000009_gene4242	2.02e-11	65.9	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
k59_1472715_1	882086.SacxiDRAFT_2610	1.32e-13	75.1	COG1522@1|root,COG1940@1|root,COG1522@2|Bacteria,COG1940@2|Bacteria,2I2XH@201174|Actinobacteria,4E2FA@85010|Pseudonocardiales	201174|Actinobacteria	GK	Transcriptional regulator sugar kinase	-	-	-	-	-	-	-	-	-	-	-	-	ROK
k59_569179_1	1172190.M947_04710	6.3e-115	357.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1304074_1	1121931.AUHG01000011_gene1936	1.77e-121	357.0	28HNS@1|root,2Z7WY@2|Bacteria,4NDYC@976|Bacteroidetes,1HYVW@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4856)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4856
k59_61064_1	1469557.JSWF01000025_gene1269	1.85e-86	259.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_1472717_2	1492737.FEM08_30660	2.12e-183	518.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1HWQZ@117743|Flavobacteriia,2NWMP@237|Flavobacterium	976|Bacteroidetes	S	Phosphotransferase enzyme family	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
k59_1472717_3	1492737.FEM08_30670	1.23e-64	205.0	COG1209@1|root,COG1209@2|Bacteria,4NF32@976|Bacteroidetes,1HZD0@117743|Flavobacteriia	976|Bacteroidetes	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
k59_682682_1	497321.C664_16133	3.41e-52	181.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,2KUHM@206389|Rhodocyclales	206389|Rhodocyclales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_682682_2	132113.XP_003492791.1	1.34e-10	60.5	COG0085@1|root,COG0222@1|root,KOG0214@2759|Eukaryota,KOG1715@2759|Eukaryota,39VWS@33154|Opisthokonta,3BM6Z@33208|Metazoa,3DDNE@33213|Bilateria	33208|Metazoa	K	DNA-directed 5'-3' RNA polymerase activity	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1189821_1	929558.SMGD1_2315	6.72e-12	64.3	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1189821_2	326298.Suden_1343	3.51e-84	255.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_1021428_1	1380600.AUYN01000009_gene1141	2.55e-90	273.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_286956_1	504487.JCM19302_2999	2.29e-63	195.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k59_230653_1	1123514.KB905899_gene1457	2.43e-99	299.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,4610C@72273|Thiotrichales	72273|Thiotrichales	N	Belongs to the bacterial flagellin family	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1304099_1	1121931.AUHG01000017_gene1525	6.52e-131	382.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_795441_2	929558.SMGD1_0885	5.81e-213	594.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2YMRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_795441_3	929558.SMGD1_0884	6.28e-39	137.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2YMKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_400052_1	317025.Tcr_1135	4.82e-86	266.0	COG0842@1|root,COG0842@2|Bacteria,1QVX7@1224|Proteobacteria,1T2MQ@1236|Gammaproteobacteria,463U8@72273|Thiotrichales	72273|Thiotrichales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_286982_1	1121935.AQXX01000131_gene2788	1.97e-21	94.0	COG0834@1|root,COG0834@2|Bacteria,1RDZV@1224|Proteobacteria,1S4VJ@1236|Gammaproteobacteria,1XKQX@135619|Oceanospirillales	135619|Oceanospirillales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_908264_1	76869.PputGB1_5350	8.41e-60	205.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1YVX4@136845|Pseudomonas putida group	1236|Gammaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	iECNA114_1301.ECNA114_3794,iECOK1_1307.ECOK1_4092,iECP_1309.ECP_3748,iECS88_1305.ECS88_4065,iECSF_1327.ECSF_3486,iLF82_1304.LF82_2165,iNRG857_1313.NRG857_18145,iUMN146_1321.UM146_18405,iUTI89_1310.UTI89_C4195,ic_1306.c4475	ACT_4,HD_4,RelA_SpoT,TGS
k59_400066_1	944547.ABLL_0146	8.53e-91	271.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_400066_2	572480.Arnit_0153	5.05e-20	85.9	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K07221,ko:K09807	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	OMP_b-brl,SIMPL
k59_400073_1	1476902.A0A067ZIM0_9CAUD	5.22e-16	72.4	4QDWB@10239|Viruses,4QRZ6@28883|Caudovirales	28883|Caudovirales	S	Pfam:Phage_TAC_7	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_400073_2	1476902.A0A067ZJA9_9CAUD	1.68e-66	206.0	4QGAP@10239|Viruses,4QWU3@35237|dsDNA viruses  no RNA stage,4QQUA@28883|Caudovirales,4QIA5@10662|Myoviridae	10662|Myoviridae	S	Phage tail tube protein FII	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_400084_1	1123518.ARWI01000001_gene251	2.16e-99	299.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,46027@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_400084_2	90814.KL370891_gene1035	3.48e-14	70.1	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,4610T@72273|Thiotrichales	72273|Thiotrichales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_1021496_2	1094466.KQS_08135	4.57e-05	43.9	2A9PF@1|root,30YWA@2|Bacteria,4PCVC@976|Bacteroidetes,1IDD6@117743|Flavobacteriia,2NY26@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_795496_1	319224.Sputcn32_2894	3e-118	365.0	COG0582@1|root,COG0582@2|Bacteria,1QYZQ@1224|Proteobacteria,1RSG8@1236|Gammaproteobacteria,2QDKW@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM phage integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_851170_1	90813.JQMT01000001_gene923	1.89e-145	416.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,45ZY5@72273|Thiotrichales	72273|Thiotrichales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_851170_2	1123518.ARWI01000001_gene125	1.81e-44	150.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,45ZYP@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_287025_1	1121890.AUDO01000014_gene1402	1.97e-65	224.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia,2NU0K@237|Flavobacterium	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k59_456693_1	709032.Sulku_1313	1.99e-46	162.0	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42MWR@68525|delta/epsilon subdivisions,2YNCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_117484_1	1484460.JSWG01000009_gene523	5.62e-141	430.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	GO:0001871,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0004185,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0009987,GO:0010467,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030246,GO:0030247,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044421,GO:0051604,GO:0070008,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:2001070	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_117484_2	1178825.ALIH01000001_gene2474	1.08e-196	552.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HXME@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_117484_3	1178825.ALIH01000001_gene2476	5.32e-54	180.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
k59_1077086_1	1121931.AUHG01000012_gene2811	4.46e-122	359.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
k59_1699161_1	411154.GFO_0125	1.66e-101	302.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1699161_2	1121931.AUHG01000010_gene783	2.57e-74	222.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1I32H@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
k59_512467_1	1353528.DT23_01020	2.39e-98	298.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,2XPEC@285107|Thioclava	28211|Alphaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	tauR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
k59_512467_2	1353528.DT23_01025	1.2e-43	155.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria,2XNU3@285107|Thioclava	28211|Alphaproteobacteria	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_1246662_1	1123514.KB905901_gene78	3.61e-79	247.0	COG5662@1|root,COG5662@2|Bacteria,1RJ4M@1224|Proteobacteria,1S23M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Protein of unknown function (DUF3379)	EBIG1770	-	-	-	-	-	-	-	-	-	-	-	DUF3379
k59_1246662_2	1123514.KB905901_gene77	1.14e-33	121.0	COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S7BJ@1236|Gammaproteobacteria,462N7@72273|Thiotrichales	72273|Thiotrichales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_625999_1	1300005.R9RHA1_9CAUD	4.26e-55	193.0	4QBG0@10239|Viruses,4QWYZ@35237|dsDNA viruses  no RNA stage,4QSGM@28883|Caudovirales,4QP2Q@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_738955_2	1207076.ALAT01000105_gene1898	1.68e-35	127.0	2E3EW@1|root,33ISG@2|Bacteria,1MZ6T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1134165_1	2340.JV46_17810	6.19e-52	186.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_343013_1	1121931.AUHG01000012_gene2672	4e-183	516.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1HWSR@117743|Flavobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_964777_1	411154.GFO_3470	4.88e-48	168.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
k59_964777_2	1121931.AUHG01000010_gene485	2.81e-56	184.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_174307_2	1380600.AUYN01000001_gene2709	3.23e-143	410.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,1HX2I@117743|Flavobacteriia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
k59_174307_3	1380600.AUYN01000001_gene2708	1.53e-124	371.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
k59_1021563_1	563040.Saut_1447	8.51e-29	108.0	COG2863@1|root,COG2863@2|Bacteria,1NBPD@1224|Proteobacteria,42VXS@68525|delta/epsilon subdivisions,2YQ9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1021563_2	929558.SMGD1_0332	1.2e-91	272.0	COG0476@1|root,COG0476@2|Bacteria,1P1FY@1224|Proteobacteria,42PK6@68525|delta/epsilon subdivisions,2YNCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_795564_1	411154.GFO_3359	1.64e-120	359.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1755870_1	1537915.JU57_06770	1.5e-63	206.0	2F29Z@1|root,33V7Y@2|Bacteria,1NVGY@1224|Proteobacteria	1224|Proteobacteria	S	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k59_1755870_2	1537917.JU82_02370	1.25e-39	141.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,42N4A@68525|delta/epsilon subdivisions,2YMSZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylglucosamine 2-epimerase	legG	GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576	3.2.1.184	ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
k59_1699224_1	553178.CAPGI0001_0361	4.2e-23	94.7	COG0346@1|root,COG0346@2|Bacteria,4PBRN@976|Bacteroidetes,1IFFH@117743|Flavobacteriia,1ESXX@1016|Capnocytophaga	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_739004_1	326298.Suden_1487	2.33e-30	117.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2YMEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_343058_1	572480.Arnit_1864	4.72e-88	264.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2YPMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_1077165_1	1123514.KB905899_gene1248	7.62e-32	123.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,4607H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_1077165_2	90813.JQMT01000001_gene1212	2e-20	88.2	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,45ZNU@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_739012_1	1283300.ATXB01000001_gene428	3.93e-100	298.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1XFWX@135618|Methylococcales	135618|Methylococcales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_343063_1	1123037.AUDE01000001_gene1780	3.57e-54	183.0	28ID4@1|root,2Z8FC@2|Bacteria,4NFYZ@976|Bacteroidetes,1HXPK@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_343063_2	1453498.LG45_06670	7.92e-05	45.1	COG3184@1|root,COG3184@2|Bacteria,4NT1K@976|Bacteroidetes,1I3ZH@117743|Flavobacteriia,2NWFP@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
k59_343067_1	1123367.C666_00330	2.04e-75	234.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,2KVAN@206389|Rhodocyclales	206389|Rhodocyclales	H	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k59_1246743_1	90814.KL370891_gene929	6.06e-19	81.3	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1246743_2	1123518.ARWI01000001_gene370	1.38e-53	182.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,4600J@72273|Thiotrichales	72273|Thiotrichales	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_230830_1	1250006.JHZZ01000001_gene2242	5.17e-172	497.0	COG5434@1|root,COG5434@2|Bacteria,4NTBW@976|Bacteroidetes	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_1361083_2	1569209.BBPH01000092_gene1248	5.67e-23	99.0	COG4134@1|root,COG4134@2|Bacteria,1MWJ7@1224|Proteobacteria,2TSU7@28211|Alphaproteobacteria,2PYEX@265|Paracoccus	28211|Alphaproteobacteria	S	Bacterial extracellular solute-binding protein	ynjB	-	-	ko:K02055,ko:K05777	ko02024,map02024	M00192,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_1135596_1	1472418.BBJC01000002_gene912	1.81e-08	57.4	28M5B@1|root,2ZAJ4@2|Bacteria,1R7Y9@1224|Proteobacteria,2U94U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1530899_1	411154.GFO_3463	4.75e-161	480.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_232480_1	1123518.ARWI01000001_gene2073	2.27e-20	91.3	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,460NE@72273|Thiotrichales	72273|Thiotrichales	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_232480_2	1123514.KB905899_gene468	1.06e-24	99.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,462R8@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_740376_1	563040.Saut_0587	2.19e-176	513.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_740376_2	1244083.CSUNSWCD_2408	1.97e-32	115.0	2E94U@1|root,333DN@2|Bacteria,1P6X3@1224|Proteobacteria,42TTX@68525|delta/epsilon subdivisions,2YPST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_288676_2	504487.JCM19302_4259	3.99e-143	412.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1HXRB@117743|Flavobacteriia	976|Bacteroidetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Lipocalin_2
k59_1190857_1	203122.Sde_1496	4.48e-36	135.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,464NA@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iEC042_1314.EC042_2616	tRNA-synt_1c
k59_119069_1	326298.Suden_0312	4.32e-34	124.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2YMVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_119069_2	929558.SMGD1_0945	2.47e-42	139.0	2A4QD@1|root,30TBM@2|Bacteria,1PD3Y@1224|Proteobacteria,42WKS@68525|delta/epsilon subdivisions,2YQFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5972_1	155515.JP36_04535	0.000308	43.9	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1Y7XF@135625|Pasteurellales	135625|Pasteurellales	S	Competence protein F	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_5972_2	1123518.ARWI01000001_gene1224	3.99e-119	347.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux
k59_684477_1	1121012.AUKX01000014_gene2773	8.17e-118	353.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1IFBT@117743|Flavobacteriia,23HUH@178469|Arenibacter	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
k59_684477_2	746697.Aeqsu_1992	2.05e-180	517.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1305889_1	1380600.AUYN01000001_gene2932	2.84e-37	143.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_797226_1	411154.GFO_0470	9.75e-154	437.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1HXR1@117743|Flavobacteriia	976|Bacteroidetes	P	Ca2 Na antiporter	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_232508_1	1123228.AUIH01000022_gene3079	1.63e-98	295.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XIFT@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
k59_740397_1	1123518.ARWI01000001_gene1439	4.55e-82	248.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,460Z3@72273|Thiotrichales	72273|Thiotrichales	O	Thiol disulfide interchange protein	-	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
k59_740397_2	1123518.ARWI01000001_gene1440	1.71e-88	269.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_176012_1	1096769.Pelub83DRAFT_0656	0.000317	43.5	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,4BQ5K@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941,ko:K18824	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Pterin_bind
k59_176012_2	1123518.ARWI01000001_gene2248	7.52e-33	128.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,45ZVM@72273|Thiotrichales	72273|Thiotrichales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_288719_1	864073.HFRIS_000285	1.09e-37	147.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,475ZU@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	methyl-accepting chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,TarH
k59_288719_2	317025.Tcr_0549	3.87e-60	192.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,462F6@72273|Thiotrichales	72273|Thiotrichales	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
k59_6005_1	1123517.JOMR01000001_gene762	7.03e-13	73.9	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,46291@72273|Thiotrichales	72273|Thiotrichales	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	-	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k59_966504_1	1121931.AUHG01000011_gene1704	4.32e-171	486.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1644545_1	1158318.ATXC01000001_gene944	9.24e-33	116.0	COG0011@1|root,COG0011@2|Bacteria,2G43G@200783|Aquificae	200783|Aquificae	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_1644545_2	367737.Abu_0453	6.41e-43	154.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YTJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_966511_1	1249975.JQLP01000005_gene2778	1.82e-105	327.0	COG3451@1|root,COG3451@2|Bacteria,4NER7@976|Bacteroidetes,1HWN6@117743|Flavobacteriia,2P7F5@244698|Gillisia	976|Bacteroidetes	U	Domain of unknown function, B. Theta Gene description (DUF3875)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3875,DUF87
k59_288731_1	411154.GFO_3078	7.31e-156	467.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1135655_1	411154.GFO_2228	1.95e-99	301.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_458480_1	391603.FBALC1_02867	1.4e-159	462.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1HXF9@117743|Flavobacteriia	976|Bacteroidetes	E	acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1305946_1	306281.AJLK01000180_gene5288	1.5e-22	101.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1JI2C@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_176050_1	90814.KL370892_gene2326	1.27e-52	185.0	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria,46275@72273|Thiotrichales	72273|Thiotrichales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_176050_2	983917.RGE_38690	0.00012	45.8	COG2199@1|root,COG2703@1|root,COG2703@2|Bacteria,COG3706@2|Bacteria,1R592@1224|Proteobacteria,2VS5X@28216|Betaproteobacteria,1KP9G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	PT	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hemerythrin,dCache_1
k59_401851_1	1379698.RBG1_1C00001G0394	1.98e-44	160.0	COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_966532_1	1178825.ALIH01000003_gene2005	6.7e-188	551.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_966532_2	1197477.IA57_03310	5.94e-37	136.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HWPQ@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_627773_1	90814.KL370891_gene145	6.09e-213	605.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4603G@72273|Thiotrichales	72273|Thiotrichales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1474612_1	1123514.KB905899_gene707	1.05e-123	366.0	COG0225@1|root,COG0229@1|root,COG0526@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,COG0526@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,Redoxin,SelR
k59_1078780_1	1178825.ALIH01000019_gene1248	3.21e-160	460.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
k59_6052_1	62928.azo2070	4.31e-157	449.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,2KVAQ@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_62938_1	944546.ABED_0099	2.16e-13	68.2	COG3218@1|root,COG3218@2|Bacteria,1NP49@1224|Proteobacteria,43BBZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_62938_2	283942.IL1253	4.61e-09	58.5	COG3637@1|root,COG3637@2|Bacteria,1NG7I@1224|Proteobacteria,1SC99@1236|Gammaproteobacteria,2QGAD@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_119167_1	1392490.JHZX01000001_gene3024	8.73e-101	323.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_627794_1	563040.Saut_0919	8.4e-157	454.0	COG0539@1|root,COG1107@1|root,COG0539@2|Bacteria,COG1107@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_458538_1	411154.GFO_2127	1.56e-104	316.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_797331_1	1168067.JAGP01000001_gene694	4.54e-115	362.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1588258_1	1380600.AUYN01000009_gene1208	6.49e-70	220.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1588258_2	1392489.JPOL01000003_gene249	6.94e-67	213.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1HWYR@117743|Flavobacteriia,2XI90@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_1135719_1	1121931.AUHG01000012_gene2788	9.45e-70	217.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_1248410_1	572480.Arnit_0366	2.06e-110	327.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42RTF@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Di-haem cytochrome c peroxidase	mauG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
k59_1474650_1	929558.SMGD1_1729	7.48e-31	123.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1616085_1	1123228.AUIH01000040_gene2930	3.7e-77	243.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XIG9@135619|Oceanospirillales	135619|Oceanospirillales	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_145104_1	985255.APHJ01000031_gene2817	9.86e-95	283.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1HXPC@117743|Flavobacteriia,2P5G0@244698|Gillisia	976|Bacteroidetes	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_1671325_1	1121931.AUHG01000010_gene566	1.98e-141	405.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1HY7T@117743|Flavobacteriia	976|Bacteroidetes	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_202869_1	1137281.D778_02029	1.81e-175	496.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1HXC6@117743|Flavobacteriia	976|Bacteroidetes	V	proteins, homologs of microcin C7 resistance protein MccF	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_202869_2	1347342.BN863_1160	8.24e-189	541.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_541119_1	1124983.PFLCHA0_c06830	1.21e-19	84.3	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1YPGV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0560	DHquinase_II
k59_89816_1	161934.XP_010686968.1	0.000965	44.3	COG1806@1|root,2QQ1R@2759|Eukaryota,37NRA@33090|Viridiplantae,3GFS0@35493|Streptophyta	35493|Streptophyta	S	pyruvate, phosphate dikinase regulatory protein	-	GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.7.11.32,2.7.4.27	ko:K20115	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_89816_2	1191523.MROS_1656	8.88e-36	130.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_825168_1	1121931.AUHG01000011_gene1768	1.6e-74	227.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_1104953_1	1380600.AUYN01000009_gene1453	7.72e-81	245.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1104953_2	1178825.ALIH01000008_gene732	2.51e-124	354.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,1HX5C@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
k59_1104953_3	216432.CA2559_07440	5.12e-137	394.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,1HZPW@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
k59_370895_1	1178825.ALIH01000001_gene2296	8.68e-78	243.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_654634_1	1122599.AUGR01000011_gene4084	3.53e-34	124.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XHNR@135619|Oceanospirillales	135619|Oceanospirillales	E	ABC transporter	aapP	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_654634_2	1089551.KE386572_gene4205	2.5e-33	124.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,4BPRV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_1556752_2	572480.Arnit_1336	4.99e-24	96.7	2A4DJ@1|root,30SZD@2|Bacteria,1PCJ7@1224|Proteobacteria,430CF@68525|delta/epsilon subdivisions,2YRYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1161853_2	641491.DND132_1162	2.68e-26	116.0	COG0642@1|root,COG4191@1|root,COG0642@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2X8BX@28221|Deltaproteobacteria,2MHFZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1048972_1	641526.ADIWIN_2756	1.46e-86	262.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,1HYUI@117743|Flavobacteriia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_1558924_2	1347342.BN863_2950	2.46e-84	263.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1HXK1@117743|Flavobacteriia	976|Bacteroidetes	S	FAD-dependent	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
k59_990287_1	323850.Shew_3841	4.62e-100	311.0	COG4773@1|root,COG4773@2|Bacteria,1QTT0@1224|Proteobacteria,1T2PF@1236|Gammaproteobacteria,2Q95D@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TIGRFAM TonB-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1210543_1	1178825.ALIH01000002_gene1117	6e-88	284.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1389599_1	1178825.ALIH01000004_gene2954	2.49e-30	112.0	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,1I199@117743|Flavobacteriia	976|Bacteroidetes	I	Acyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1389599_2	1484460.JSWG01000015_gene995	2.05e-58	201.0	COG4206@1|root,COG4206@2|Bacteria,4PM79@976|Bacteroidetes,1IJK7@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_430628_1	637905.SVI_2218	1.71e-11	72.4	COG2199@1|root,COG3706@2|Bacteria,1RFH9@1224|Proteobacteria,1S72F@1236|Gammaproteobacteria,2QB4R@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
k59_33338_1	1380600.AUYN01000011_gene956	1.13e-113	353.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_768570_1	1163408.UU9_07034	4.53e-12	62.4	COG2841@1|root,COG2841@2|Bacteria,1QB8P@1224|Proteobacteria,1T6SZ@1236|Gammaproteobacteria,1X83B@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF465)	uptF	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_768570_2	666685.R2APBS1_0565	8.36e-35	130.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales	135614|Xanthomonadales	E	Cystathionine beta-synthase	cysB	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k59_1107174_1	385682.AFSL01000069_gene1470	5.45e-167	473.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,2FQJ2@200643|Bacteroidia,3XJBY@558415|Marinilabiliaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_262045_1	1178825.ALIH01000006_gene1547	8.37e-125	363.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_262045_2	1296415.JACC01000038_gene1876	3.32e-10	58.5	2DZM8@1|root,32VDQ@2|Bacteria,4NSF0@976|Bacteroidetes,1I3WI@117743|Flavobacteriia,2YJDZ@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_487488_2	1353276.JADR01000007_gene1295	2.03e-39	137.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
k59_1164120_1	709032.Sulku_0745	4.68e-76	243.0	COG3829@1|root,COG3829@2|Bacteria,1QQYY@1224|Proteobacteria,42ZWP@68525|delta/epsilon subdivisions,2YRT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_430657_1	1484460.JSWG01000007_gene3105	3.57e-101	323.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_92132_1	323850.Shew_0466	8.59e-90	290.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QAY1@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_33374_1	658612.MD26_17070	1.13e-45	164.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria	1224|Proteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_33374_2	1123518.ARWI01000001_gene569	5.74e-09	57.8	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,45ZPQ@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1210572_1	991.IW20_08330	2.58e-21	110.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2P050@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
k59_1277370_1	411154.GFO_3498	1.84e-60	194.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia	976|Bacteroidetes	EF	ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_827474_1	1001585.MDS_0640	6.68e-38	137.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,1RQK2@1236|Gammaproteobacteria,1YJ35@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF561)	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_205110_1	1121896.JMLU01000040_gene2921	8.32e-77	239.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1HZGV@117743|Flavobacteriia,2NS7G@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1559033_1	367737.Abu_0943	1e-47	177.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,431XQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Haemagluttinin repeat	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg_2,Haemagg_act
k59_318016_1	1476902.A0A067ZJB4_9CAUD	4.61e-87	268.0	4QAMU@10239|Viruses,4QV4U@35237|dsDNA viruses  no RNA stage,4QPEV@28883|Caudovirales,4QI0J@10662|Myoviridae	10662|Myoviridae	S	Baseplate J-like protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025	-	-	-	-	-	-	-	-	-	-	-
k59_1107264_1	563040.Saut_1685	2.25e-119	371.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,43C3Q@68525|delta/epsilon subdivisions,2YTG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1787122_1	563040.Saut_1736	7.29e-102	303.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42MJP@68525|delta/epsilon subdivisions,2YMVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	pglG	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_33438_1	94122.Shewana3_1736	2.06e-39	144.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,2Q8R7@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_33438_2	323850.Shew_1550	6.08e-38	142.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,2Q9IH@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM FAD linked oxidase domain protein	ydiJ	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0097159,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1277427_1	1168067.JAGP01000001_gene535	2.4e-32	121.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,46071@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_1277427_2	1123514.KB905899_gene797	4.46e-68	213.0	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,1S3VA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)	phnN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019634,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.23	ko:K05774	ko00030,map00030	-	R06836	RC00002	ko00000,ko00001,ko01000	-	-	iAF1260.b4094,iB21_1397.B21_03926,iBWG_1329.BWG_3809,iECBD_1354.ECBD_3936,iECB_1328.ECB_03966,iECDH10B_1368.ECDH10B_4285,iECDH1ME8569_1439.ECDH1ME8569_3953,iECD_1391.ECD_03966,iEKO11_1354.EKO11_4224,iEcDH1_1363.EcDH1_3897,iEcolC_1368.EcolC_3932,iJO1366.b4094,iSSON_1240.SSON_4270,iUMNK88_1353.UMNK88_4960,iY75_1357.Y75_RS21315	AAA_18,Guanylate_kin
k59_1504747_1	1123366.TH3_04969	3.27e-05	47.4	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2TU9T@28211|Alphaproteobacteria,2JRXT@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2199 FOG GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1504747_2	90814.KL370891_gene1782	1.08e-178	507.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,461NY@72273|Thiotrichales	72273|Thiotrichales	U	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
k59_1618482_1	1123518.ARWI01000001_gene1592	4.84e-143	416.0	COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,45ZYI@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k59_1336196_1	1168289.AJKI01000002_gene2506	8.18e-37	142.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia,3XJ4Y@558415|Marinilabiliaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_1107302_1	1137281.D778_00745	7.06e-114	346.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1673669_1	1168067.JAGP01000001_gene627	5.21e-27	114.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,45ZTE@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_1787159_1	338966.Ppro_1754	1.97e-112	335.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria,43UEN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_430760_1	929558.SMGD1_2292	3.67e-32	117.0	COG1619@1|root,COG1619@2|Bacteria,1Q23R@1224|Proteobacteria,42UXX@68525|delta/epsilon subdivisions,2YPD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_430760_2	929558.SMGD1_2291	2.57e-116	352.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_768714_1	1123037.AUDE01000006_gene1167	1.8e-31	119.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
k59_768714_2	616991.JPOO01000003_gene498	9.66e-61	198.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1HYNA@117743|Flavobacteriia,23GG5@178469|Arenibacter	976|Bacteroidetes	E	Aminotransferase class I and II	hisC	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_657058_1	869213.JCM21142_197	1e-37	139.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_1730014_1	1392490.JHZX01000001_gene3339	1.75e-51	172.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1HX0Z@117743|Flavobacteriia	976|Bacteroidetes	K	GTP cyclohydrolase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1730014_2	1347342.BN863_14180	3.94e-265	729.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1HWW2@117743|Flavobacteriia	976|Bacteroidetes	H	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1730022_1	620914.JH621246_gene2703	7.29e-13	66.6	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia,2YGZ1@290174|Aquimarina	976|Bacteroidetes	F	Amino acid kinase family	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1730022_2	504472.Slin_2390	9.09e-19	84.3	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
k59_430783_1	1232410.KI421412_gene350	2.83e-128	371.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,43TBK@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_205224_1	411154.GFO_0182	1.31e-111	357.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_205224_2	1121931.AUHG01000010_gene834	0.000293	42.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_1336240_1	1178825.ALIH01000008_gene717	1.4e-39	142.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1336240_2	504487.JCM19302_3086	5.59e-58	197.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_1673702_1	1492737.FEM08_16070	2.13e-175	502.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,1HXH0@117743|Flavobacteriia,2NSD0@237|Flavobacterium	976|Bacteroidetes	G	Pfam FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1673702_2	1250232.JQNJ01000001_gene2716	7.42e-219	609.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1HZCR@117743|Flavobacteriia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_1107357_1	411154.GFO_3284	1.65e-136	391.0	COG0463@1|root,COG0463@2|Bacteria,4NK1T@976|Bacteroidetes,1HZ1Q@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1050878_1	305700.B447_12307	9.34e-50	169.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,2KUYT@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k59_1050878_2	1123367.C666_05190	1.32e-42	147.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,2KUTB@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_827631_1	411154.GFO_1011	2.24e-32	118.0	2AQR4@1|root,31FYV@2|Bacteria,4NQYS@976|Bacteroidetes,1I3DS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_827631_2	411154.GFO_1008	4.11e-32	118.0	COG0204@1|root,COG0204@2|Bacteria,4NG70@976|Bacteroidetes,1HXMA@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1277525_1	589865.DaAHT2_0927	1.25e-10	61.6	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,42WJ3@68525|delta/epsilon subdivisions,2X5E1@28221|Deltaproteobacteria,2MKUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1277525_2	1278309.KB907111_gene3385	5.38e-05	50.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1446312_1	1123367.C666_07475	5e-105	317.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_1210705_1	1121931.AUHG01000011_gene1754	3.54e-146	419.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_1389846_1	411154.GFO_2738	1.64e-68	223.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1HWXI@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
k59_827653_1	411154.GFO_2927	1.62e-222	635.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_1787245_1	1168067.JAGP01000001_gene1396	2.26e-23	92.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,46002@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_3882_2	1380600.AUYN01000009_gene2126	8.57e-155	456.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_229971_1	313598.MED152_00335	8.43e-43	159.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia,3VWAR@52959|Polaribacter	976|Bacteroidetes	M	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_1415953_1	323850.Shew_1056	3.78e-110	321.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,2QBAA@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0008150,GO:0009314,GO:0009628,GO:0050896	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_1076373_2	90813.JQMT01000001_gene55	6.45e-90	267.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,460M5@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_1076373_3	90814.KL370891_gene40	1e-83	254.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales	72273|Thiotrichales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_1245937_1	1380600.AUYN01000009_gene973	6.43e-106	313.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1755091_1	1380600.AUYN01000006_gene552	2.47e-125	373.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
k59_1698481_1	1565129.JSFF01000001_gene1168	7.54e-154	451.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,2Q9EH@267890|Shewanellaceae	1236|Gammaproteobacteria	L	SMART helicase c2	dinG	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0033677,GO:0033680,GO:0042623,GO:0048037,GO:0050896,GO:0051276,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071840,GO:0140097,GO:0140098	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k59_1303416_1	94122.Shewana3_0107	1.05e-117	357.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,1RQJI@1236|Gammaproteobacteria,2Q8ZI@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Translation elongation factor	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_625306_2	322710.Avin_52450	9.96e-41	153.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1528789_1	1380600.AUYN01000001_gene2542	4.69e-112	331.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_568581_1	313603.FB2170_09206	2.79e-202	572.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
k59_1755107_1	323850.Shew_1984	6.32e-45	150.0	2DRYR@1|root,33DQT@2|Bacteria,1NG9I@1224|Proteobacteria,1T068@1236|Gammaproteobacteria,2QCHP@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1585676_1	211586.SO_0314	3.22e-136	404.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,1RMVF@1236|Gammaproteobacteria,2QB3Q@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	speC	GO:0003674,GO:0003824,GO:0004586,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A3126	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
k59_1303424_1	983544.Lacal_2672	3.55e-113	347.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1303431_1	1123228.AUIH01000013_gene234	9.1e-96	295.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1XHAP@135619|Oceanospirillales	135619|Oceanospirillales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_511808_1	867900.Celly_2848	1.8e-81	264.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HZ0H@117743|Flavobacteriia,1FABK@104264|Cellulophaga	976|Bacteroidetes	M	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_850534_1	317025.Tcr_0021	5.87e-105	320.0	COG2199@1|root,COG3706@2|Bacteria,1R6GI@1224|Proteobacteria,1T2M9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_230036_1	1123228.AUIH01000054_gene3597	2.27e-59	193.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales	135619|Oceanospirillales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_907704_1	1123518.ARWI01000001_gene34	1.45e-72	235.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,45ZSE@72273|Thiotrichales	72273|Thiotrichales	C	dihydrolipoamide dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_625345_1	411154.GFO_2370	4.83e-106	337.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_399486_1	572480.Arnit_0454	5.79e-102	314.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_60540_1	425104.Ssed_1505	6.42e-124	372.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,2Q9YV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	betT	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_456051_1	90814.KL370891_gene144	2.01e-65	212.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,4611X@72273|Thiotrichales	72273|Thiotrichales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_342353_1	1178825.ALIH01000001_gene2272	9.5e-106	327.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_738327_1	693979.Bache_R0042	1.85e-112	350.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,4AK8A@815|Bacteroidaceae	976|Bacteroidetes	G	glycosyl hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_794862_1	411154.GFO_0208	3.09e-33	123.0	COG2885@1|root,COG2885@2|Bacteria,4NH36@976|Bacteroidetes,1HWN0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_794862_2	411154.GFO_0207	2.07e-122	353.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k59_1585734_2	1034807.FBFL15_2674	6.52e-306	837.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,1HY2E@117743|Flavobacteriia,2NUBM@237|Flavobacterium	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
k59_1585734_3	1121897.AUGO01000008_gene2673	1.76e-22	92.4	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,1HWTV@117743|Flavobacteriia,2NU9A@237|Flavobacterium	976|Bacteroidetes	IQ	Gluconate 5-dehydrogenase	idnO	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
k59_850569_1	1121931.AUHG01000010_gene445	6.31e-171	484.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_850569_2	1121931.AUHG01000010_gene446	1.02e-132	379.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,1HYMQ@117743|Flavobacteriia	976|Bacteroidetes	G	Aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k59_850569_3	1121931.AUHG01000010_gene447	1.48e-62	201.0	COG1638@1|root,COG1638@2|Bacteria,4NGV4@976|Bacteroidetes,1HZ02@117743|Flavobacteriia	976|Bacteroidetes	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_907748_1	690850.Desaf_2527	1.43e-12	72.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M7RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
k59_3990_1	1123518.ARWI01000001_gene661	1.01e-102	304.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,460PW@72273|Thiotrichales	72273|Thiotrichales	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_3990_2	317025.Tcr_1486	8.51e-62	196.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,46335@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_3990_3	1485545.JQLW01000007_gene716	0.000177	44.7	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria	1224|Proteobacteria	E	aminopeptidase N	pepN	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042	DUF3458,DUF3458_C,Peptidase_M1
k59_794889_1	360104.CCC13826_0860	3.95e-11	62.4	COG1040@1|root,COG1040@2|Bacteria,1Q1C2@1224|Proteobacteria,42T93@68525|delta/epsilon subdivisions,2YPEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transformation system protein	ctsW	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k59_511901_1	391603.FBALC1_00722	7.7e-06	46.6	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_511901_3	1178825.ALIH01000013_gene501	1.73e-29	114.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1HYJS@117743|Flavobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_173686_2	90814.KL370891_gene1360	1.28e-186	544.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,460Z9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1076527_2	313603.FB2170_05740	1.15e-55	189.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1HXT6@117743|Flavobacteriia,2PIAE@252356|Maribacter	976|Bacteroidetes	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k59_682157_2	572480.Arnit_1570	1.15e-84	254.0	2C388@1|root,30ZIR@2|Bacteria,1RFG7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1642363_1	1278309.KB907102_gene135	6.81e-08	55.5	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XHNH@135619|Oceanospirillales	135619|Oceanospirillales	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
k59_1642363_2	1123518.ARWI01000001_gene356	8.59e-47	155.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,4610K@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k59_342406_1	1235803.C825_04452	2.01e-26	105.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,2FNA5@200643|Bacteroidia,22W0D@171551|Porphyromonadaceae	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_342406_2	1484460.JSWG01000009_gene174	2.26e-247	681.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1HY1Q@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_342406_3	504487.JCM19302_4100	3.86e-104	309.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1528898_1	1347342.BN863_4150	2.9e-222	621.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1HXI4@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_1528898_2	504487.JCM19302_3465	9.75e-26	101.0	COG0242@1|root,COG0242@2|Bacteria,4NPNS@976|Bacteroidetes,1I2ND@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	DUF1684,Pep_deformylase
k59_1755223_1	411154.GFO_1693	3.03e-70	226.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1HXX6@117743|Flavobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_626811_1	572480.Arnit_2108	3e-178	499.0	COG1621@1|root,COG1621@2|Bacteria,1RCMP@1224|Proteobacteria,432Y7@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_5204_2	1121931.AUHG01000015_gene1153	3.28e-78	233.0	2ADU8@1|root,313JX@2|Bacteria,4NQA4@976|Bacteroidetes,1I2S9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118273_1	1392489.JPOL01000002_gene1562	4.02e-25	101.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2XIF1@283735|Leeuwenhoekiella	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_118273_2	504487.JCM19302_1518	6.2e-76	229.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_118273_3	313598.MED152_07915	3.98e-62	192.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia,3VWQ3@52959|Polaribacter	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_343797_1	945713.IALB_0036	6.65e-68	219.0	COG1066@1|root,COG1066@2|Bacteria	2|Bacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_1022357_1	291112.PAU_01449	6.79e-42	150.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k59_400931_1	1178825.ALIH01000005_gene318	1.5e-92	297.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
k59_400931_2	983544.Lacal_0130	5.23e-128	370.0	COG1596@1|root,COG1596@2|Bacteria,4NFXJ@976|Bacteroidetes,1HWKA@117743|Flavobacteriia	976|Bacteroidetes	M	Periplasmic protein involved in polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
k59_1247473_1	929558.SMGD1_0037	7.86e-08	53.9	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2YN6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
k59_1247473_2	929558.SMGD1_1827	3.32e-126	363.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2YMWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_965598_1	504487.JCM19302_1142	1.43e-89	268.0	COG3145@1|root,COG3145@2|Bacteria,4NFEG@976|Bacteroidetes,1HWRD@117743|Flavobacteriia	976|Bacteroidetes	L	Alkylated DNA repair protein	alkB	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
k59_1247475_1	1469557.JSWF01000030_gene3526	2.84e-32	126.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia	976|Bacteroidetes	L	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
k59_1247475_2	1178825.ALIH01000003_gene2053	2.07e-26	100.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1I17S@117743|Flavobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
k59_796361_1	1172190.M947_09900	9.74e-20	84.3	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42MTC@68525|delta/epsilon subdivisions,2YMSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cosR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_796361_2	563040.Saut_0691	4.32e-34	120.0	COG1539@1|root,COG1539@2|Bacteria,1RHII@1224|Proteobacteria,42V1R@68525|delta/epsilon subdivisions,2YQ8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	dihydroneopterin aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_287871_1	317025.Tcr_0905	3.99e-72	226.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,460CX@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_287871_2	1123518.ARWI01000001_gene2449	6.96e-47	163.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4607S@72273|Thiotrichales	72273|Thiotrichales	T	nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1643751_1	1123518.ARWI01000001_gene1326	2.99e-85	305.0	COG2304@1|root,COG4254@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria,1QU09@1224|Proteobacteria,1S7VE@1236|Gammaproteobacteria,461I1@72273|Thiotrichales	72273|Thiotrichales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118303_1	411154.GFO_1972	6.63e-56	183.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_118303_2	411154.GFO_1584	6.21e-59	191.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,1HWY9@117743|Flavobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_5239_1	1121931.AUHG01000010_gene564	1.22e-42	151.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia	976|Bacteroidetes	N	Cell envelope biogenesis protein OmpA	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1360368_1	1123234.AUKI01000022_gene2224	6.61e-114	343.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_457601_1	391600.ABRU01000013_gene3397	4.98e-39	154.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2KH9A@204458|Caulobacterales	204458|Caulobacterales	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,HAMP,MCPsignal
k59_909083_2	411154.GFO_1480	2.75e-103	300.0	29FZ2@1|root,302WT@2|Bacteria,4NPJZ@976|Bacteroidetes,1I29R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1134898_1	1380600.AUYN01000001_gene2925	3.02e-232	647.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1HX65@117743|Flavobacteriia	976|Bacteroidetes	J	TRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_1134898_2	1380600.AUYN01000001_gene2923	8.96e-103	300.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,1HZTW@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_1134898_3	504487.JCM19302_2148	1.2e-25	103.0	COG3642@1|root,COG3642@2|Bacteria,4NIJK@976|Bacteroidetes,1HZEK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Lipopolysaccharide kinase (Kdo WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_1190381_1	76114.ebA3446	3.79e-55	189.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria,2KUUB@206389|Rhodocyclales	206389|Rhodocyclales	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_77487_2	755732.Fluta_0770	5.88e-38	129.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1I2TE@117743|Flavobacteriia,2PAYV@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_358255_2	697282.Mettu_3919	9.11e-10	60.8	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_753839_1	411154.GFO_2767	2.18e-12	66.6	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1HX68@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_753839_2	411154.GFO_2766	5.59e-112	325.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1I27S@117743|Flavobacteriia	976|Bacteroidetes	M	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
k59_190329_1	90814.KL370891_gene1175	2.35e-34	131.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,460C3@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_190329_2	1123518.ARWI01000001_gene104	3.34e-32	124.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,460ES@72273|Thiotrichales	72273|Thiotrichales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340,ko:K12538	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00328,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,1.B.17.1,2.A.6.2	-	-	OEP
k59_1262629_1	323850.Shew_1276	2.6e-140	406.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,2Q9WD@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM isocitrate lyase and phosphorylmutase	aceA	GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b4015,iAF1260.b4015,iB21_1397.B21_03847,iBWG_1329.BWG_3671,iE2348C_1286.E2348C_4318,iEC042_1314.EC042_4377,iEC55989_1330.EC55989_4500,iECABU_c1320.ECABU_c45310,iECBD_1354.ECBD_4022,iECB_1328.ECB_03887,iECDH10B_1368.ECDH10B_4204,iECDH1ME8569_1439.ECDH1ME8569_3871,iECD_1391.ECD_03887,iECED1_1282.ECED1_4722,iECIAI1_1343.ECIAI1_4235,iECIAI39_1322.ECIAI39_4401,iECNA114_1301.ECNA114_4164,iECO103_1326.ECO103_4759,iECO111_1330.ECO111_4827,iECO26_1355.ECO26_5119,iECP_1309.ECP_4225,iECSE_1348.ECSE_4300,iECSF_1327.ECSF_3865,iECUMN_1333.ECUMN_4541,iECW_1372.ECW_m4374,iEKO11_1354.EKO11_4310,iETEC_1333.ETEC_4270,iEcDH1_1363.EcDH1_3982,iEcE24377_1341.EcE24377A_4557,iEcHS_1320.EcHS_A4249,iEcSMS35_1347.EcSMS35_4469,iEcolC_1368.EcolC_4015,iJN746.PP_4116,iJO1366.b4015,iJR904.b4015,iLF82_1304.LF82_0012,iNRG857_1313.NRG857_20015,iSDY_1059.SDY_4328,iUMNK88_1353.UMNK88_4859,iWFL_1372.ECW_m4374,iY75_1357.Y75_RS20880	ICL
k59_246924_1	504487.JCM19302_4102	8.34e-106	311.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1HWWH@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_246924_2	388467.A19Y_1466	1.83e-16	75.9	COG1898@1|root,COG1898@2|Bacteria,1G0QA@1117|Cyanobacteria,1H6ZK@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_1262630_1	1123228.AUIH01000022_gene3091	1.06e-123	374.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales	135619|Oceanospirillales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_699270_1	443143.GM18_2247	1.13e-06	53.1	COG0778@1|root,COG0778@2|Bacteria,1RDTR@1224|Proteobacteria	1224|Proteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_699270_2	1504981.KO116_1165	9.87e-19	86.3	COG2244@1|root,COG2244@2|Bacteria,1PMCM@1224|Proteobacteria,1T9CG@1236|Gammaproteobacteria,1XMN7@135619|Oceanospirillales	135619|Oceanospirillales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_77528_2	929558.SMGD1_0937	2.14e-138	392.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_584960_1	1197477.IA57_10945	1.38e-06	48.9	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_584960_2	1178825.ALIH01000002_gene895	6.26e-74	228.0	2F1YU@1|root,33UY6@2|Bacteria,4P2VN@976|Bacteroidetes,1I8MH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_584960_3	1178825.ALIH01000002_gene896	8.88e-26	105.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_303012_1	1565129.JSFF01000011_gene1985	1.74e-122	357.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,2QA59@267890|Shewanellaceae	1236|Gammaproteobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735	SAICAR_synt
k59_976879_1	717772.THIAE_00915	4.29e-106	322.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,45ZQ1@72273|Thiotrichales	1236|Gammaproteobacteria	P	NMT1-like family	nrtA	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_1658770_1	85643.Tmz1t_1748	3.62e-78	256.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,2KVHX@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1771944_1	1123228.AUIH01000010_gene3936	1e-36	133.0	COG2770@1|root,COG2770@2|Bacteria,1QZYS@1224|Proteobacteria	1224|Proteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP
k59_867479_2	1250006.JHZZ01000001_gene1450	9.25e-06	54.3	COG3291@1|root,COG3291@2|Bacteria,4PMBH@976|Bacteroidetes,1IMSY@117743|Flavobacteriia,3VXB4@52959|Polaribacter	976|Bacteroidetes	L	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1148795_1	1123514.KB905899_gene1889	8.92e-62	192.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4615J@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_1148795_2	290512.Paes_1639	4.68e-56	199.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1FDMS@1090|Chlorobi	1090|Chlorobi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_358342_1	1121931.AUHG01000011_gene2087	6.21e-78	234.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_132719_1	266748.HY04_03040	2.24e-08	56.2	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HX4D@117743|Flavobacteriia,3ZUNH@59732|Chryseobacterium	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_132719_2	1538644.KO02_21840	6.93e-14	78.2	COG2956@1|root,COG2956@2|Bacteria,4NGUC@976|Bacteroidetes,1IQX2@117747|Sphingobacteriia	976|Bacteroidetes	G	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1658811_1	411154.GFO_1663	2.96e-80	250.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,1HXWZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_246997_1	1123518.ARWI01000001_gene582	1.85e-27	113.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria,461TZ@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_246997_2	1123518.ARWI01000001_gene583	1.45e-50	170.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,461S9@72273|Thiotrichales	72273|Thiotrichales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1489239_1	1197477.IA57_12570	2.7e-105	312.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_1320580_1	929558.SMGD1_1000	1.43e-78	240.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42MJZ@68525|delta/epsilon subdivisions,2YN8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_247008_1	76114.ebA4492	8.41e-79	247.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,2KUHR@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
k59_1658839_1	563040.Saut_0268	3.19e-64	209.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	general secretion pathway protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_77609_1	1347342.BN863_32770	2.85e-78	242.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1HWNB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_77609_3	1122225.AULQ01000002_gene525	1.34e-66	202.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_77609_4	504487.JCM19302_3839	9.83e-287	787.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia	976|Bacteroidetes	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_1037090_1	1172190.M947_07055	3.96e-77	234.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2YMN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_1431879_1	765913.ThidrDRAFT_0556	2.27e-56	180.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,1T530@1236|Gammaproteobacteria,1X2VM@135613|Chromatiales	135613|Chromatiales	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
k59_1658846_1	1197477.IA57_11185	3.02e-73	223.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1HWZW@117743|Flavobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_358396_1	1380600.AUYN01000001_gene2415	3.31e-109	334.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_1092417_1	411154.GFO_3476	1.29e-124	360.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_813832_1	1278309.KB907099_gene3091	1.9e-102	304.0	COG1092@1|root,COG1092@2|Bacteria,1R6GY@1224|Proteobacteria,1RZ4H@1236|Gammaproteobacteria,1XNXK@135619|Oceanospirillales	135619|Oceanospirillales	J	S-adenosylmethionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_SAM
k59_530459_1	1122951.ATUE01000006_gene933	6.29e-15	68.9	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
k59_530459_2	1123518.ARWI01000001_gene1730	8.41e-14	70.1	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,45ZPY@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1264394_1	1137281.D778_02672	1.47e-92	286.0	COG0793@1|root,COG0793@2|Bacteria,4NIS9@976|Bacteroidetes,1HZR4@117743|Flavobacteriia	976|Bacteroidetes	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_813844_1	765912.Thimo_0781	8.23e-24	97.8	2AAD4@1|root,30ZP1@2|Bacteria,1NBWF@1224|Proteobacteria,1SB2S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_869312_1	1298593.TOL_2284	8.51e-137	401.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XHWP@135619|Oceanospirillales	135619|Oceanospirillales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_359926_1	2340.JV46_13540	6.32e-101	310.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1J589@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1491148_1	411154.GFO_2389	8.02e-150	429.0	COG1960@1|root,COG1960@2|Bacteria,4NFD4@976|Bacteroidetes,1HWQD@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1604863_1	929558.SMGD1_2303	4.62e-115	331.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2YMFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_1604863_2	1172190.M947_02205	4e-141	410.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_643827_1	1123517.JOMR01000001_gene1342	2.58e-08	59.7	COG3307@1|root,COG3307@2|Bacteria,1Q9AR@1224|Proteobacteria,1RUX5@1236|Gammaproteobacteria,462D4@72273|Thiotrichales	72273|Thiotrichales	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k59_643827_2	1123296.JQKE01000054_gene1384	3.94e-36	135.0	28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2VJZB@28216|Betaproteobacteria,2KSEU@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1264425_1	572480.Arnit_2669	1.08e-143	428.0	COG0699@1|root,COG0699@2|Bacteria,1NAXY@1224|Proteobacteria,42NA8@68525|delta/epsilon subdivisions,2YN7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_248825_1	945713.IALB_0399	4.02e-83	260.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_1322513_1	1121931.AUHG01000010_gene386	3.46e-99	301.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1322513_2	1121931.AUHG01000010_gene385	2.12e-102	297.0	COG1917@1|root,COG1917@2|Bacteria,4PKJ0@976|Bacteroidetes,1IJAI@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
k59_1546173_1	411154.GFO_3353	2.08e-64	206.0	COG0787@1|root,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1HWKS@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
k59_1546173_2	1121931.AUHG01000010_gene343	4.43e-83	247.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
k59_925080_1	1469557.JSWF01000044_gene695	2.76e-82	272.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NEPS@976|Bacteroidetes,1HYQ1@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_7,TPR_8
k59_1150544_1	1449063.JMLS01000016_gene924	1.17e-52	177.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,4HDAC@91061|Bacilli,26W7B@186822|Paenibacillaceae	91061|Bacilli	S	phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k59_1150544_2	1178825.ALIH01000007_gene1694	8.49e-19	80.1	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_643874_1	572480.Arnit_1545	1.1e-58	197.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,42RST@68525|delta/epsilon subdivisions,2YPD3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_643874_2	572480.Arnit_0833	3.32e-07	51.6	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions,2YR4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_79288_1	1168067.JAGP01000001_gene491	3.05e-90	276.0	COG1271@1|root,COG1271@2|Bacteria,1R5SQ@1224|Proteobacteria,1RY58@1236|Gammaproteobacteria,461TF@72273|Thiotrichales	72273|Thiotrichales	C	oxidase subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1038911_1	1123518.ARWI01000001_gene821	1.22e-115	344.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,460CN@72273|Thiotrichales	72273|Thiotrichales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_1038911_2	1123518.ARWI01000001_gene822	4.08e-83	251.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,4613A@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
k59_474659_1	1123514.KB905899_gene914	2.82e-17	80.5	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,45ZWB@72273|Thiotrichales	72273|Thiotrichales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
k59_474659_2	1123518.ARWI01000001_gene112	1.8e-66	213.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,460Y9@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_869381_1	742766.HMPREF9455_02586	7.47e-57	187.0	COG0518@1|root,COG0518@2|Bacteria,4NMFC@976|Bacteroidetes,2FS4D@200643|Bacteroidia,22Y23@171551|Porphyromonadaceae	976|Bacteroidetes	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k59_869381_2	1168067.JAGP01000001_gene1526	9.52e-80	241.0	COG1416@1|root,COG1416@2|Bacteria,1QACS@1224|Proteobacteria,1SIA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_869381_3	1208321.D104_16515	7.54e-36	128.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XJN2@135619|Oceanospirillales	135619|Oceanospirillales	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k59_978204_1	1235800.C819_02062	0.000307	45.4	COG2755@1|root,COG2755@2|Bacteria,1TS75@1239|Firmicutes,24DPZ@186801|Clostridia,27IYV@186928|unclassified Lachnospiraceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_978204_3	1121012.AUKX01000046_gene2680	6.4e-109	318.0	COG0500@1|root,COG0500@2|Bacteria,4NFT7@976|Bacteroidetes,1I0W7@117743|Flavobacteriia,23HT6@178469|Arenibacter	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_1433511_1	929558.SMGD1_2383	1.35e-95	288.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,43DST@68525|delta/epsilon subdivisions,2YNGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase-4, component G	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
k59_1094189_1	1123514.KB905899_gene1980	1.51e-70	221.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,1T1K8@1236|Gammaproteobacteria,4611F@72273|Thiotrichales	72273|Thiotrichales	I	Thioesterase domain	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_1717102_1	1286632.P278_01220	1.42e-59	187.0	2E34H@1|root,32Y4K@2|Bacteria,4NV4B@976|Bacteroidetes,1I579@117743|Flavobacteriia	976|Bacteroidetes	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
k59_1717102_2	1408813.AYMG01000007_gene4349	3.58e-13	67.4	COG2227@1|root,COG2227@2|Bacteria,4NJ5M@976|Bacteroidetes,1IRZH@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
k59_869407_1	1123514.KB905902_gene230	3.31e-38	140.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,46012@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_869407_2	1123518.ARWI01000001_gene455	1.33e-118	357.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales	72273|Thiotrichales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_37620_1	1121931.AUHG01000010_gene69	2.11e-246	682.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1563262_1	1172190.M947_01190	3.91e-128	386.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1281609_1	653733.Selin_2388	1.7e-37	142.0	COG0326@1|root,COG0326@2|Bacteria	2|Bacteria	O	unfolded protein binding	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_209407_1	1123518.ARWI01000001_gene1098	1.33e-10	60.5	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,45ZXX@72273|Thiotrichales	72273|Thiotrichales	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_209407_2	90814.KL370891_gene175	4.26e-104	314.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,45ZW2@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1791328_2	313628.LNTAR_13177	2.81e-06	53.1	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
k59_96453_1	1172190.M947_07320	5.21e-61	200.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria	1224|Proteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1213986_1	945713.IALB_1083	7.59e-59	204.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CarboxypepD_reg,LVIVD,TSP_3
k59_1394018_1	90814.KL370891_gene347	4.06e-200	557.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,45ZR2@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_1450472_1	1121931.AUHG01000012_gene2821	8.37e-86	270.0	COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,1HY8J@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_546216_1	563040.Saut_1453	6.44e-79	256.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_151689_1	1336233.JAEH01000058_gene2022	4.6e-131	382.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,2Q8JB@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	yeiM	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_37705_1	1123228.AUIH01000003_gene950	1.32e-122	360.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHMY@135619|Oceanospirillales	135619|Oceanospirillales	IQ	catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1111615_1	1296415.JACC01000051_gene3721	9.55e-124	366.0	COG0438@1|root,COG0438@2|Bacteria,4NF7J@976|Bacteroidetes,1IIKH@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_1054305_1	1380600.AUYN01000009_gene1493	1.12e-67	213.0	2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_886590_1	1178825.ALIH01000003_gene2139	4.4e-49	161.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_886590_2	1123037.AUDE01000013_gene490	3.3e-76	235.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the FBPase class 1 family	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_267835_1	223926.28808950	1.28e-21	102.0	COG1345@1|root,COG4412@1|root,COG1345@2|Bacteria,COG4412@2|Bacteria,1RKAD@1224|Proteobacteria,1S8JD@1236|Gammaproteobacteria,1XSHD@135623|Vibrionales	135623|Vibrionales	Q	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
k59_605060_1	1336233.JAEH01000016_gene3028	7.5e-110	326.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,2Q9ZU@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	iPC815.YPO2896,iYL1228.KPN_02862	Aminotran_5
k59_212369_2	323850.Shew_2987	2.57e-83	253.0	COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,2Q9XP@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator, LysR family	metR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016597,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_325148_1	709032.Sulku_1661	1.39e-20	85.9	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SWG@68525|delta/epsilon subdivisions,2YPN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Chemotaxis protein CheW	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_325148_2	1304885.AUEY01000002_gene310	2.95e-06	56.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2MIVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_1794331_1	1120963.KB894492_gene1556	7.97e-54	179.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,2Q08F@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_548718_1	1123228.AUIH01000002_gene1546	6.89e-23	91.3	COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1XMJC@135619|Oceanospirillales	135619|Oceanospirillales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
k59_548718_2	1123228.AUIH01000002_gene1545	8.8e-33	125.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XHBX@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_722992_1	504487.JCM19302_3002	3.83e-191	538.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_605064_1	1380600.AUYN01000009_gene1816	8.61e-131	378.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_605064_2	983544.Lacal_1872	1.87e-43	152.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1794335_1	411154.GFO_2232	1.89e-65	214.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
k59_664344_1	1237149.C900_00779	6.91e-67	218.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,47NVA@768503|Cytophagia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_40349_1	745718.JADT01000005_gene72	5.02e-36	128.0	COG3637@1|root,COG3637@2|Bacteria,4NI8B@976|Bacteroidetes,1HZ9J@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_325158_1	408672.NBCG_03360	1.97e-08	54.3	COG1670@1|root,COG1670@2|Bacteria,2GJRX@201174|Actinobacteria,4DREV@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_1453168_1	458817.Shal_4181	3.83e-82	261.0	COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,1RYUG@1236|Gammaproteobacteria,2Q9QW@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_605093_1	411154.GFO_3440	2.08e-105	310.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_99537_1	1123326.JFBL01000011_gene212	7.22e-54	192.0	COG0643@1|root,COG2208@1|root,COG0643@2|Bacteria,COG2208@2|Bacteria,1R7CN@1224|Proteobacteria,42PXU@68525|delta/epsilon subdivisions,2YNWD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c
k59_1794359_1	317025.Tcr_2024	1.38e-63	216.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,PAS_4
k59_775666_1	411154.GFO_0073	8.21e-47	160.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia	976|Bacteroidetes	M	probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_605121_1	1042377.AFPJ01000007_gene1921	7.18e-34	134.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,4657M@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
k59_548778_1	929558.SMGD1_0945	1.22e-42	140.0	2A4QD@1|root,30TBM@2|Bacteria,1PD3Y@1224|Proteobacteria,42WKS@68525|delta/epsilon subdivisions,2YQFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40408_1	1121931.AUHG01000016_gene1076	8.04e-143	406.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_1284641_1	1123518.ARWI01000001_gene2173	1.44e-95	290.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_997393_2	317025.Tcr_1543	6.72e-103	318.0	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,45ZXU@72273|Thiotrichales	72273|Thiotrichales	NT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
k59_212465_1	313603.FB2170_07914	7.43e-210	590.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_212465_2	1121875.KB907547_gene3151	1.25e-47	154.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes,1I9XX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1453245_1	929558.SMGD1_2858	4.47e-50	169.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO
k59_1453245_2	929558.SMGD1_2859	1.31e-09	58.5	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_1343300_1	504487.JCM19302_2944	8.03e-98	303.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_1453251_1	1178825.ALIH01000008_gene813	4.09e-205	591.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia	976|Bacteroidetes	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
k59_1396616_1	1123234.AUKI01000016_gene2981	4.72e-06	50.4	COG4974@1|root,COG4974@2|Bacteria,4NX3Q@976|Bacteroidetes,1HXCN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_1396616_2	644076.SCH4B_2793	9.73e-42	140.0	COG3422@1|root,COG3422@2|Bacteria,1N0S6@1224|Proteobacteria,2U8P6@28211|Alphaproteobacteria,4NCDA@97050|Ruegeria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1508)	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
k59_723116_1	572480.Arnit_0709	4.14e-118	357.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_40471_1	1278309.KB907102_gene247	2.73e-56	182.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,1RP1E@1236|Gammaproteobacteria,1XJ43@135619|Oceanospirillales	135619|Oceanospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_40471_2	1117958.PE143B_0109930	1.16e-23	95.9	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	intracellular protease amidase	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k59_1624310_2	1123514.KB905901_gene33	9.24e-56	178.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,460YI@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_1453286_1	1121931.AUHG01000019_gene2978	2.58e-118	347.0	COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,1HY9N@117743|Flavobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k59_325310_1	1123518.ARWI01000001_gene1881	1.39e-113	342.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,45ZSG@72273|Thiotrichales	72273|Thiotrichales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_664511_1	305700.B447_19099	2.01e-64	219.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,2WGPI@28216|Betaproteobacteria,2KUI8@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_664511_2	305700.B447_19104	2.09e-12	63.5	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,2VX4E@28216|Betaproteobacteria,2M033@206389|Rhodocyclales	206389|Rhodocyclales	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1284744_1	1123518.ARWI01000001_gene1103	0.0	1134.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4609J@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1284744_2	1123518.ARWI01000001_gene1104	9.19e-24	99.8	COG0845@1|root,COG0845@2|Bacteria,1NKWA@1224|Proteobacteria,1RP0X@1236|Gammaproteobacteria,460TD@72273|Thiotrichales	72273|Thiotrichales	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_1566383_1	411154.GFO_2263	5.52e-146	420.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
k59_1284768_1	1125973.JNLC01000012_gene937	1.95e-07	52.8	COG2084@1|root,COG2084@2|Bacteria,1MWR4@1224|Proteobacteria,2U157@28211|Alphaproteobacteria,3JRTW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	MA20_20495	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_1284768_2	1304883.KI912532_gene1685	1.47e-23	98.6	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2WFNY@28216|Betaproteobacteria,2KVWM@206389|Rhodocyclales	206389|Rhodocyclales	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k59_212582_1	1250278.JQNQ01000001_gene3156	3.1e-151	467.0	COG0178@1|root,COG0178@2|Bacteria,4NGEE@976|Bacteroidetes,1I0HF@117743|Flavobacteriia	976|Bacteroidetes	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_1114747_1	563040.Saut_1875	1.72e-12	63.2	2E7QP@1|root,30HJH@2|Bacteria,1Q381@1224|Proteobacteria,431QW@68525|delta/epsilon subdivisions,2YSC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1114747_2	1249480.B649_07995	4.63e-45	152.0	COG0352@1|root,COG0352@2|Bacteria,1NMR6@1224|Proteobacteria,42TSZ@68525|delta/epsilon subdivisions,2YPHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_437997_1	563040.Saut_2087	1.9e-68	212.0	2BEW6@1|root,328MU@2|Bacteria,1QAUA@1224|Proteobacteria,42VY6@68525|delta/epsilon subdivisions,2YQED@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_775840_1	929558.SMGD1_2539	7.19e-44	155.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_775840_2	326298.Suden_1212	1.43e-78	246.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1680743_1	929558.SMGD1_2440	3.01e-45	157.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_380261_1	411154.GFO_2215	1.01e-51	171.0	COG0642@1|root,COG0642@2|Bacteria,4NHCX@976|Bacteroidetes,1I0GU@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_380261_2	411154.GFO_2214	2.74e-56	179.0	COG2128@1|root,COG2128@2|Bacteria,4NJJV@976|Bacteroidetes,1I0NT@117743|Flavobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1453361_1	688270.Celal_1715	1.5e-115	336.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,1HXDB@117743|Flavobacteriia,1FA8N@104264|Cellulophaga	976|Bacteroidetes	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1453361_2	509635.N824_27135	1.77e-13	70.1	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes	976|Bacteroidetes	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_664580_1	1380600.AUYN01000003_gene129	6.89e-150	433.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_494682_1	929558.SMGD1_1310	1.77e-153	448.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YT16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_494682_2	929558.SMGD1_1311	7.98e-64	198.0	COG3829@1|root,COG3829@2|Bacteria,1NG3B@1224|Proteobacteria,43AE4@68525|delta/epsilon subdivisions,2YT0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_1680749_1	1430440.MGMSRv2_2721	1.46e-44	163.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2U0PD@28211|Alphaproteobacteria,2JPZE@204441|Rhodospirillales	204441|Rhodospirillales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD_5
k59_1680749_2	563040.Saut_1004	1.33e-150	434.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2YNG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_723259_1	1232410.KI421421_gene3842	6.89e-15	68.2	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,43SP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_723259_2	1232410.KI421421_gene3841	9.05e-49	156.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,43SNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_325422_1	1237149.C900_04788	4.5e-67	212.0	2E691@1|root,32WA1@2|Bacteria,4NT8M@976|Bacteroidetes,47R10@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1216907_1	1236959.BAMT01000013_gene2959	3.45e-18	85.5	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,2KKI6@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_664622_1	929558.SMGD1_0051	3.94e-116	352.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2YMEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_664622_2	1172190.M947_01275	4.51e-06	47.4	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_737699_1	745718.JADT01000005_gene88	1.8e-48	165.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,1HZQ0@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_737699_2	1469557.JSWF01000014_gene2603	1.9e-154	445.0	COG0438@1|root,COG0438@2|Bacteria,4NE53@976|Bacteroidetes,1HX83@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_624756_1	1185766.DL1_21000	2.65e-96	286.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,2XNSE@285107|Thioclava	28211|Alphaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	natD	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1529739_2	1131812.JQMS01000001_gene254	8.76e-150	433.0	COG1835@1|root,COG1835@2|Bacteria,4NR9B@976|Bacteroidetes,1IIA5@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1529739_3	1469557.JSWF01000014_gene2589	4.41e-143	416.0	COG1216@1|root,COG1216@2|Bacteria,4NFP4@976|Bacteroidetes,1I0IN@117743|Flavobacteriia	976|Bacteroidetes	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glyco_transf_7C,Glycos_transf_2
k59_1529739_4	1469557.JSWF01000014_gene2590	1.17e-117	349.0	COG0438@1|root,COG0438@2|Bacteria,4NICT@976|Bacteroidetes,1HZ2P@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
k59_1473195_1	572480.Arnit_3064	3.46e-119	352.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_1473195_2	572480.Arnit_3065	2.75e-09	57.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42PNH@68525|delta/epsilon subdivisions,2YRFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1134476_1	317025.Tcr_0418	2.93e-97	290.0	28KDQ@1|root,2ZA05@2|Bacteria,1QE8C@1224|Proteobacteria,1S0JF@1236|Gammaproteobacteria,462VG@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61559_1	1220714.L7TNL6_9CAUD	1.35e-131	406.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage,4QPWY@28883|Caudovirales,4QJW9@10662|Myoviridae	10662|Myoviridae	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61559_2	1175654.A0A0S0N5L1_9CAUD	3.42e-08	53.9	4QFYS@10239|Viruses,4QYA8@35237|dsDNA viruses  no RNA stage,4QUD0@28883|Caudovirales,4QMR9@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1756210_1	90814.KL370891_gene1814	8.88e-102	310.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
k59_1756210_2	90814.KL370891_gene1825	9.93e-23	95.1	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,45ZRJ@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_4848_1	1122225.AULQ01000007_gene2258	1.62e-31	119.0	COG1216@1|root,COG1216@2|Bacteria,4NFEP@976|Bacteroidetes,1HWUH@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_4848_2	1122225.AULQ01000007_gene2259	2.61e-139	405.0	COG0438@1|root,COG0438@2|Bacteria,4NJI5@976|Bacteroidetes,1I06C@117743|Flavobacteriia	976|Bacteroidetes	M	Exostosin family	-	-	-	-	-	-	-	-	-	-	-	-	Exostosin
k59_4848_3	391587.KAOT1_06227	3.11e-89	273.0	COG2520@1|root,COG2520@2|Bacteria,4NMFM@976|Bacteroidetes,1I33H@117743|Flavobacteriia	976|Bacteroidetes	J	Vibrio cholerae RfbT protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_4848_4	376686.Fjoh_0298	1.57e-150	447.0	COG1216@1|root,COG1216@2|Bacteria,4NI78@976|Bacteroidetes,1HXTP@117743|Flavobacteriia,2NURB@237|Flavobacterium	976|Bacteroidetes	S	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_4848_5	1178825.ALIH01000005_gene297	6.82e-196	552.0	COG0438@1|root,COG0438@2|Bacteria,4NIXA@976|Bacteroidetes,1HYIA@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_4848_6	1353276.JADR01000005_gene2540	1.53e-280	773.0	COG0707@1|root,COG0707@2|Bacteria,4PKUP@976|Bacteroidetes,1IJFS@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf,MGDG_synth
k59_4848_7	1178825.ALIH01000005_gene299	2.24e-143	410.0	COG2327@1|root,COG2327@2|Bacteria,4NEU1@976|Bacteroidetes,1HY8X@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
k59_4848_8	1178825.ALIH01000005_gene300	3.5e-192	535.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1HYI2@117743|Flavobacteriia	976|Bacteroidetes	M	Sialic acid synthase	-	-	2.5.1.132,2.5.1.56	ko:K01654,ko:K21279	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_4848_9	1178825.ALIH01000005_gene301	1.73e-218	609.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria,4NGXC@976|Bacteroidetes,1HX0H@117743|Flavobacteriia	976|Bacteroidetes	M	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	2.7.7.43,2.7.7.92,3.1.3.103,3.1.3.45	ko:K03270,ko:K21055,ko:K21749	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215,R11440	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
k59_4848_10	391598.FBBAL38_02490	1.48e-129	390.0	2C1UE@1|root,3334D@2|Bacteria,4P270@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_739272_4	1380600.AUYN01000001_gene2801	0.0	928.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_851604_1	926554.KI912617_gene4815	2.63e-68	231.0	COG0612@1|root,COG0612@2|Bacteria,1WM19@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_795918_1	1392489.JPOL01000002_gene3151	2.68e-123	372.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1I0PJ@117743|Flavobacteriia,2XJVV@283735|Leeuwenhoekiella	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_1756228_1	1123234.AUKI01000014_gene2446	3.16e-35	130.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia	976|Bacteroidetes	M	UDP-N-acetylmuramyl pentapeptide phosphotransferase	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
k59_1756228_2	488538.SAR116_1963	1.55e-23	102.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2TU8I@28211|Alphaproteobacteria,4BQ79@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
k59_569767_1	1197477.IA57_02660	1.22e-80	251.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1HXJC@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1586810_1	411154.GFO_0667	1.89e-153	437.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_683216_1	1123514.KB905901_gene140	3.59e-140	422.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,45ZS2@72273|Thiotrichales	72273|Thiotrichales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
k59_1359994_1	521674.Plim_2833	2.38e-23	95.5	2EDEG@1|root,337AV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_457158_1	1121912.AUHD01000007_gene574	0.0	905.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_343438_1	335659.S23_25060	1.4e-34	128.0	COG0824@1|root,COG0824@2|Bacteria,1R6A6@1224|Proteobacteria,2TU6J@28211|Alphaproteobacteria,3JR33@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_739308_1	709032.Sulku_1349	3.17e-54	184.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42YK0@68525|delta/epsilon subdivisions,2YRI7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_61620_1	940282.CADQ01000006_gene186	6.25e-31	119.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,2JPWP@204441|Rhodospirillales	204441|Rhodospirillales	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_61620_2	317025.Tcr_1787	2.51e-57	186.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQPA@1236|Gammaproteobacteria,461NN@72273|Thiotrichales	72273|Thiotrichales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_1643374_1	1046627.BZARG_1277	1.25e-23	99.4	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1HXWN@117743|Flavobacteriia	976|Bacteroidetes	K	RNA binding protein with S1 RNA-binding domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1643374_2	1123037.AUDE01000001_gene1905	2.5e-120	348.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
k59_1643374_3	1137281.D778_02025	3.61e-73	223.0	294YG@1|root,2ZSBD@2|Bacteria,4NNM4@976|Bacteroidetes,1I27W@117743|Flavobacteriia	976|Bacteroidetes	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
k59_1643374_4	1137281.D778_02023	3.59e-41	145.0	COG3015@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3187@2|Bacteria,4NSEQ@976|Bacteroidetes,1I4SD@117743|Flavobacteriia	976|Bacteroidetes	MP	lipoprotein NlpE involved in copper resistance	nlpE	-	-	-	-	-	-	-	-	-	-	-	META,NlpE
k59_1643374_5	504487.JCM19302_2718	9.48e-26	102.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_1529815_1	317025.Tcr_0136	2.67e-99	293.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,1SZRM@1236|Gammaproteobacteria,460HH@72273|Thiotrichales	72273|Thiotrichales	S	Molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_795959_1	1121931.AUHG01000011_gene2196	1.09e-113	348.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_61628_1	929558.SMGD1_2209	1.35e-163	478.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_1473280_1	1178825.ALIH01000009_gene1255	4.27e-137	408.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_343456_1	557393.B8QTU5_9CAUD	9.75e-59	197.0	4QE4P@10239|Viruses,4QZC2@35237|dsDNA viruses  no RNA stage,4QR3B@28883|Caudovirales,4QKAN@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_965228_1	572480.Arnit_0700	1.87e-158	459.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_174766_1	1172190.M947_07335	1.76e-52	180.0	COG2897@1|root,COG2897@2|Bacteria,1P6SN@1224|Proteobacteria,42VHJ@68525|delta/epsilon subdivisions,2YQHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_1473314_1	929558.SMGD1_1229	1.83e-32	124.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2YMJN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
k59_796004_1	411154.GFO_1818	6.82e-114	335.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.384	ko:K13327	ko00523,ko01130,map00523,map01130	M00801,M00802	R05526	RC00897	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
k59_343496_1	1380600.AUYN01000006_gene736	1.14e-171	486.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1HY6A@117743|Flavobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_512985_1	1249997.JHZW01000003_gene2707	3.35e-46	161.0	COG0526@1|root,COG0526@2|Bacteria,4NK8N@976|Bacteroidetes,1I84U@117743|Flavobacteriia,2PHWD@252356|Maribacter	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
k59_512985_2	886377.Murru_2888	1.02e-25	97.4	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
k59_400632_1	1123514.KB905899_gene534	1.64e-138	398.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4606P@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_400632_2	1123514.KB905899_gene533	5.09e-10	60.1	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,45ZR5@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_908780_1	411154.GFO_0353	1.93e-65	208.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_1643449_1	1392490.JHZX01000001_gene680	4.94e-56	184.0	COG1609@1|root,COG1609@2|Bacteria,4NFB7@976|Bacteroidetes,1HYFS@117743|Flavobacteriia	976|Bacteroidetes	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
k59_1643449_2	1353276.JADR01000008_gene827	3.85e-10	61.2	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1HWPY@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_1304715_1	411154.GFO_2999	5.94e-171	520.0	COG0784@1|root,COG1520@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1520@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NK8Q@976|Bacteroidetes,1IMWE@117743|Flavobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HTH_18,Reg_prop,SpoIIE,Y_Y_Y
k59_118007_1	1380600.AUYN01000009_gene1775	6.23e-129	377.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_118007_2	1380600.AUYN01000009_gene1774	4.55e-88	262.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,1I19Q@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1247191_1	1454004.AW11_03580	4.6e-18	85.1	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2VHA3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phospholipase, patatin family	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_1360090_1	1123367.C666_19070	5.34e-114	333.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,2KXNX@206389|Rhodocyclales	206389|Rhodocyclales	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_231310_1	663952.SDD27957_10665	4.13e-09	59.3	COG1846@1|root,COG1846@2|Bacteria,1VMZX@1239|Firmicutes,4HMTC@91061|Bacilli	91061|Bacilli	K	MarR family	-	-	-	ko:K18909	-	M00705	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MarR,MarR_2
k59_231310_2	563040.Saut_0424	3.81e-07	51.2	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_1699718_1	1172190.M947_10170	1.49e-91	293.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1586930_1	1313421.JHBV01000068_gene4634	3.46e-27	112.0	COG3335@1|root,COG3335@2|Bacteria,4NRKP@976|Bacteroidetes,1IZ9D@117747|Sphingobacteriia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_457278_1	411154.GFO_1473	2.31e-31	120.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,1HZZG@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_457278_2	411154.GFO_1474	5.46e-72	222.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1I0VV@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_457280_1	1121931.AUHG01000010_gene180	1.33e-84	260.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1756370_2	317025.Tcr_0773	2.03e-103	309.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,45ZXQ@72273|Thiotrichales	72273|Thiotrichales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_287590_1	1123517.JOMR01000001_gene271	7.06e-47	173.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,463V7@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_569912_1	1165841.SULAR_04322	6.67e-44	155.0	COG1672@1|root,COG1672@2|Bacteria,1PZGT@1224|Proteobacteria,42QN9@68525|delta/epsilon subdivisions,2YNKC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_1586945_1	1178825.ALIH01000020_gene2719	2.38e-89	266.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1HYRW@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_851763_1	616991.JPOO01000001_gene2727	4.28e-166	481.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia,23G6N@178469|Arenibacter	976|Bacteroidetes	P	CBS domain	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_796073_1	1123518.ARWI01000001_gene1876	2.63e-56	178.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,46173@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_796073_2	90814.KL370891_gene1770	1.06e-21	89.4	COG1536@1|root,COG1536@2|Bacteria,1PAHB@1224|Proteobacteria,1ST44@1236|Gammaproteobacteria,463BX@72273|Thiotrichales	72273|Thiotrichales	N	FliG C-terminal domain	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C
k59_1022111_1	391603.FBALC1_10037	7.12e-62	197.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1HWQX@117743|Flavobacteriia	976|Bacteroidetes	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_1022111_2	1484460.JSWG01000015_gene1108	3.36e-55	183.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1HX17@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_174859_1	1123518.ARWI01000001_gene1197	3.31e-130	377.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,45ZQB@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_174859_2	1123518.ARWI01000001_gene1198	1.93e-67	207.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,460UT@72273|Thiotrichales	72273|Thiotrichales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k59_5005_1	1046724.KB889873_gene2086	9.53e-57	189.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,4650E@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_1360126_1	1123514.KB905899_gene721	6.45e-84	250.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,4611W@72273|Thiotrichales	72273|Thiotrichales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_1699751_1	504487.JCM19302_343	4.27e-148	424.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_287611_1	313603.FB2170_14823	1.27e-162	476.0	2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1077685_1	313603.FB2170_07919	2.48e-66	215.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1HYK2@117743|Flavobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1148870_2	563040.Saut_0718	9.69e-99	296.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2YT6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_699402_1	411154.GFO_0047	2.14e-35	132.0	COG0668@1|root,COG0668@2|Bacteria,4NF28@976|Bacteroidetes,1HY35@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_699402_2	865937.Gilli_0749	2.63e-11	70.5	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd,TSP_3
k59_528704_1	323850.Shew_1892	6.08e-10	59.3	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,2Q9EM@267890|Shewanellaceae	1236|Gammaproteobacteria	KL	PFAM SNF2-related protein	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SWIM
k59_528704_2	1565129.JSFF01000004_gene3232	3.81e-78	234.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,2QBXE@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_415899_1	1123355.JHYO01000017_gene3597	9.57e-38	146.0	COG1235@1|root,COG2905@1|root,COG1235@2|Bacteria,COG2905@2|Bacteria,1R96I@1224|Proteobacteria,2UQQ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,cNMP_binding
k59_303151_1	143224.JQMD01000002_gene3561	1.88e-19	92.8	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
k59_528719_2	411154.GFO_2969	8.17e-77	232.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
k59_1658907_1	1178825.ALIH01000011_gene96	2.4e-31	120.0	2CEPI@1|root,2Z8PU@2|Bacteria,4NFSB@976|Bacteroidetes,1I04N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1658907_2	1380600.AUYN01000003_gene168	3.63e-50	164.0	2CIT3@1|root,32Y0C@2|Bacteria,4NUWR@976|Bacteroidetes,1I533@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
k59_699432_1	1121931.AUHG01000019_gene2986	4.1e-05	42.4	COG1476@1|root,COG1476@2|Bacteria,4NV53@976|Bacteroidetes,1I527@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k59_699432_2	1121931.AUHG01000019_gene2987	6.45e-67	206.0	2CDPK@1|root,32RR8@2|Bacteria,4NSHW@976|Bacteroidetes,1I402@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1715484_1	1537917.JU82_00195	6.26e-74	243.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YNQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1489335_1	756067.MicvaDRAFT_2789	1.73e-13	73.2	COG0745@1|root,COG2200@1|root,COG0745@2|Bacteria,COG2200@2|Bacteria,1FZXH@1117|Cyanobacteria,1HAFU@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
k59_1489335_2	90814.KL370891_gene955	6.25e-38	140.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_19320_1	1123326.JFBL01000001_gene1252	3.65e-43	158.0	COG1315@1|root,COG1315@2|Bacteria,1Q4EW@1224|Proteobacteria,42Z1K@68525|delta/epsilon subdivisions,2YR61@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Pfam:DUF342	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_585111_1	929558.SMGD1_1920	5.78e-60	198.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_77684_1	1380600.AUYN01000007_gene3437	9.24e-84	263.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_77684_2	1380600.AUYN01000007_gene3436	2.87e-134	388.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
k59_642256_1	1123518.ARWI01000001_gene966	9.39e-28	103.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1SH3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k59_642256_2	1123518.ARWI01000001_gene967	1.05e-40	149.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,45ZZ5@72273|Thiotrichales	72273|Thiotrichales	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
k59_1544371_1	90814.KL370891_gene1536	1.82e-180	528.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1544371_2	1123518.ARWI01000001_gene2120	3.18e-165	490.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1201168_1	929558.SMGD1_1599	3.46e-19	83.6	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2YREA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_1201168_2	929558.SMGD1_1600	4.59e-63	206.0	2A54K@1|root,30TT8@2|Bacteria,1Q98H@1224|Proteobacteria,4348V@68525|delta/epsilon subdivisions,2YRCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1320719_1	411154.GFO_1078	4.93e-17	76.3	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,1I199@117743|Flavobacteriia	976|Bacteroidetes	I	Acyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1320719_2	1121931.AUHG01000012_gene2826	3.94e-76	228.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1I345@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1320719_3	411154.GFO_1081	4.69e-45	158.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_77721_1	983544.Lacal_0882	1.77e-137	404.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1HWRE@117743|Flavobacteriia	976|Bacteroidetes	MU	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1603047_1	553385.JEMF01000047_gene3322	2.32e-61	211.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1262847_1	1121931.AUHG01000010_gene24	8.07e-130	404.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_358502_2	391603.FBALC1_15082	3.14e-88	263.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
k59_358502_3	745718.JADT01000007_gene2697	1.46e-23	91.7	2E3I4@1|root,32YGK@2|Bacteria,4NUQ9@976|Bacteroidetes,1I53J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_303219_1	1121918.ARWE01000001_gene3273	4.23e-161	464.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42MGQ@68525|delta/epsilon subdivisions,2WSUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_303221_1	1469557.JSWF01000044_gene592	7.5e-144	421.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1HXF9@117743|Flavobacteriia	976|Bacteroidetes	E	acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1148962_1	929558.SMGD1_2199	1.29e-73	229.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_303226_1	637905.SVI_4263	4.81e-65	202.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,2Q9Q6@267890|Shewanellaceae	1236|Gammaproteobacteria	U	UPF0056 inner membrane protein	yhgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_303226_2	1565129.JSFF01000027_gene3305	4.56e-09	58.5	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria,2Q8XN@267890|Shewanellaceae	1236|Gammaproteobacteria	O	peptidase M6 immune inhibitor A	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PKD,Peptidase_M6
k59_528805_1	1336233.JAEH01000014_gene3497	1.04e-68	209.0	COG1539@1|root,COG1539@2|Bacteria,1RDHQ@1224|Proteobacteria,1S4Q3@1236|Gammaproteobacteria,2QCKY@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Dihydroneopterin aldolase	folX	-	5.1.99.7	ko:K07589	ko00790,map00790	-	R11082	RC01479	ko00000,ko00001,ko01000	-	-	-	FolB
k59_528805_2	1336233.JAEH01000014_gene3496	0.000422	42.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,2QAEM@267890|Shewanellaceae	1236|Gammaproteobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1772175_1	706191.PANA_3380	1.02e-41	156.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,3VZ75@53335|Pantoea	1236|Gammaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_77755_2	1168067.JAGP01000001_gene122	3.16e-43	142.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S765@1236|Gammaproteobacteria,462BA@72273|Thiotrichales	72273|Thiotrichales	C	Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
k59_1037247_1	1123228.AUIH01000067_gene2153	5.25e-60	192.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,1XRUJ@135619|Oceanospirillales	135619|Oceanospirillales	Q	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_1375123_2	929558.SMGD1_2412	1.28e-51	168.0	29DMK@1|root,300JF@2|Bacteria,1Q6BD@1224|Proteobacteria,432QV@68525|delta/epsilon subdivisions,2YSKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_19393_1	929558.SMGD1_1455	6.9e-78	249.0	COG1315@1|root,COG1315@2|Bacteria,1Q4EW@1224|Proteobacteria,42Z1K@68525|delta/epsilon subdivisions,2YR61@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Pfam:DUF342	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_247191_1	1380600.AUYN01000009_gene1790	7.57e-182	522.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_132928_1	1121912.AUHD01000005_gene1676	1.04e-68	233.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1772189_1	326298.Suden_0967	2.31e-35	138.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YN16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF EAL family protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,Hemerythrin,PAS_4,PAS_9
k59_1201224_1	929558.SMGD1_0303	7.26e-90	277.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
k59_1037263_1	1120963.KB894500_gene66	6.87e-45	165.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q025@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_642345_1	219305.MCAG_02679	7.83e-13	67.0	2DXRV@1|root,3467M@2|Bacteria,2IKBE@201174|Actinobacteria,4DDDI@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_473162_1	563040.Saut_0489	1.89e-17	80.1	2AINN@1|root,31954@2|Bacteria,1NDHA@1224|Proteobacteria,42Z7Y@68525|delta/epsilon subdivisions,2YR4T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_473162_2	1206729.BAFZ01000089_gene2349	2e-14	73.2	COG0500@1|root,COG2226@2|Bacteria,2IMIR@201174|Actinobacteria,4FZ5H@85025|Nocardiaceae	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1262897_1	1443665.JACA01000036_gene2174	3.32e-110	326.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia,2YICC@290174|Aquimarina	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_867721_1	667014.Thein_1831	2.91e-08	59.7	COG2204@1|root,COG2204@2|Bacteria,2GIFH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Magnesium chelatase, subunit ChlI	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1715593_1	1565129.JSFF01000031_gene2984	7.41e-65	201.0	COG3043@1|root,COG3043@2|Bacteria,1RHGD@1224|Proteobacteria,1S84V@1236|Gammaproteobacteria,2QBSD@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	-	GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
k59_585204_1	90814.KL370891_gene1068	3.47e-165	473.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales	72273|Thiotrichales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_528841_1	1121918.ARWE01000001_gene3199	4.39e-51	187.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
k59_358565_1	572480.Arnit_0873	1.85e-16	76.6	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2YNP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_358565_2	572480.Arnit_0874	3.34e-67	216.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2YNPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_416058_1	1137281.D778_02691	1.63e-176	500.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes,1HZCU@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_923524_1	985255.APHJ01000027_gene918	1.98e-50	183.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NHMH@976|Bacteroidetes,1HZTE@117743|Flavobacteriia	976|Bacteroidetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
k59_358574_1	1347369.CCAD010000024_gene1497	3.73e-26	115.0	COG5001@1|root,COG5001@2|Bacteria,1UI7N@1239|Firmicutes,4ISN0@91061|Bacilli,1ZS9J@1386|Bacillus	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MHYT,PAS,PAS_4,PAS_9
k59_1715613_1	1380600.AUYN01000001_gene2902	1e-182	520.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_1603145_1	929558.SMGD1_0008	6.9e-136	417.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1375161_1	1123518.ARWI01000001_gene1584	1.05e-106	309.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300	LuxS
k59_1375161_2	90814.KL370892_gene2113	2.31e-46	154.0	2DSP5@1|root,33GW9@2|Bacteria,1NIK6@1224|Proteobacteria,1SISY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1375161_3	1168067.JAGP01000001_gene289	2.14e-80	251.0	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_923550_1	1380600.AUYN01000001_gene2490	1.32e-116	351.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_923550_2	745718.JADT01000012_gene982	8.97e-47	156.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1I1XH@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
k59_1605658_1	1172190.M947_02915	6.53e-41	138.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_587413_1	411154.GFO_3414	3.1e-137	395.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
k59_587413_2	411154.GFO_3415	2.58e-18	83.2	COG0457@1|root,COG4547@1|root,COG0457@2|Bacteria,COG4547@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia	976|Bacteroidetes	H	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_925819_1	575590.HMPREF0156_00976	4.2e-60	195.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
k59_1491916_1	1565129.JSFF01000020_gene1581	3.33e-113	336.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,2Q8V9@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Citrate transporter	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_587414_1	563040.Saut_0440	7.11e-41	149.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1774675_1	945713.IALB_1803	8.07e-73	235.0	COG4365@1|root,COG4365@2|Bacteria	2|Bacteria	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
k59_1546882_1	929558.SMGD1_0956	1.47e-62	202.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2YNAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1546882_2	572480.Arnit_1624	4.31e-52	169.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2YRGB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k59_1661386_1	929558.SMGD1_1241	3.75e-90	281.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1661386_2	563040.Saut_2163	2.12e-87	258.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2YPJI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_1661386_3	563040.Saut_2164	1.8e-48	156.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2YPWS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k59_1661386_4	563040.Saut_2165	7.8e-72	218.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_475381_1	1484460.JSWG01000009_gene250	9.66e-46	163.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k59_475381_2	641526.ADIWIN_0628	1.61e-27	103.0	2E8WY@1|root,32NN9@2|Bacteria,4P9RM@976|Bacteroidetes,1I43V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_832446_1	980584.AFPB01000172_gene1509	9.76e-10	57.8	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia,406AP@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
k59_832446_2	1121931.AUHG01000012_gene2719	3.12e-55	173.0	COG2921@1|root,COG2921@2|Bacteria,4NSCF@976|Bacteroidetes,1I49D@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k59_832446_3	411154.GFO_1446	2.99e-107	311.0	COG3911@1|root,COG3911@2|Bacteria,4NNT6@976|Bacteroidetes,1I25D@117743|Flavobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k59_832446_4	411154.GFO_1445	7.55e-98	301.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1HX0Y@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_1510027_2	311403.Arad_9276	1.79e-06	50.4	COG3238@1|root,COG3238@2|Bacteria,1N843@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
k59_210370_1	1178825.ALIH01000005_gene130	1.35e-13	68.9	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_266355_1	1123518.ARWI01000001_gene1044	1.86e-175	529.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_377952_1	1168067.JAGP01000001_gene1202	7.13e-111	335.0	COG2199@1|root,COG2199@2|Bacteria,1P29Y@1224|Proteobacteria,1RS7H@1236|Gammaproteobacteria,461VY@72273|Thiotrichales	72273|Thiotrichales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
k59_1564284_1	929558.SMGD1_1441	1.28e-47	154.0	COG0789@1|root,COG0789@2|Bacteria,1Q3QJ@1224|Proteobacteria,42XN5@68525|delta/epsilon subdivisions,2YR08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_1564284_2	929558.SMGD1_0177	2.13e-54	172.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2YPX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_1564284_3	1355374.JARU01000001_gene357	3.41e-18	77.4	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2YQSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_1564284_4	326298.Suden_0837	5.57e-39	138.0	COG0745@1|root,COG0745@2|Bacteria,1QGBK@1224|Proteobacteria,42T0C@68525|delta/epsilon subdivisions,2YPNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_887479_1	1336245.JAGO01000010_gene992	2.44e-29	120.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XH2S@135619|Oceanospirillales	135619|Oceanospirillales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1214780_1	317025.Tcr_1802	2.57e-55	180.0	COG1082@1|root,COG1082@2|Bacteria,1Q3WR@1224|Proteobacteria,1S04R@1236|Gammaproteobacteria,461MT@72273|Thiotrichales	72273|Thiotrichales	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1214780_2	1123514.KB905899_gene1362	3.83e-98	293.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,4616F@72273|Thiotrichales	72273|Thiotrichales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1451433_1	1506583.JQJY01000003_gene3302	7.5e-89	265.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1I1G2@117743|Flavobacteriia,2NUNG@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1678766_1	1278309.KB907106_gene1263	3.53e-21	92.0	COG3851@1|root,COG3851@2|Bacteria,1QUAD@1224|Proteobacteria,1RMGY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	uhpB	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07675,ko:K20263	ko02020,ko02024,map02020,map02024	M00473,M00818	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,MASE1
k59_1735080_1	563040.Saut_0114	9.48e-124	363.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions,2YN01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fad-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_266386_1	563040.Saut_1265	4.24e-171	486.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_603133_1	411154.GFO_3580	4.21e-171	506.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1HWNX@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF3991,Plug,TonB_dep_Rec,Toprim_2
k59_1622981_1	90814.KL370891_gene1926	4.79e-138	407.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,4605W@72273|Thiotrichales	72273|Thiotrichales	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_38694_1	563040.Saut_2156	7.54e-118	348.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_38694_2	1172190.M947_02620	1.48e-07	51.6	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1510102_1	425104.Ssed_0693	6.2e-107	312.0	2CE0Z@1|root,33PGD@2|Bacteria,1NRBE@1224|Proteobacteria,1SJZB@1236|Gammaproteobacteria,2QB7F@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Nucleoside-specific channel-forming protein, Tsx	-	-	-	-	-	-	-	-	-	-	-	-	Channel_Tsx
k59_1622993_2	983545.Glaag_2627	1.11e-07	55.5	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RRTP@1236|Gammaproteobacteria,464NN@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_152687_1	1123514.KB905899_gene1123	5.61e-80	247.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,4609B@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_1055171_1	62928.azo3579	1.34e-125	373.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2VHAK@28216|Betaproteobacteria,2KUSP@206389|Rhodocyclales	206389|Rhodocyclales	H	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k59_1510115_1	504487.JCM19302_2370	3.18e-54	171.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1564368_1	1172190.M947_10245	1.19e-44	161.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_1564368_2	563040.Saut_0475	2.66e-10	60.5	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_323324_1	326298.Suden_1461	4.47e-46	159.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_97539_1	1121011.AUCB01000005_gene2323	2.19e-45	155.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia,23G6F@178469|Arenibacter	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
k59_97539_2	1121875.KB907547_gene2949	2.7e-62	193.0	COG0346@1|root,COG0346@2|Bacteria,4NQ3F@976|Bacteroidetes,1I2U9@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_1214846_1	867900.Celly_2848	8.64e-43	157.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HZ0H@117743|Flavobacteriia,1FABK@104264|Cellulophaga	976|Bacteroidetes	M	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_210472_1	572480.Arnit_1559	1.74e-196	565.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_210483_1	929558.SMGD1_2819	1.91e-88	281.0	COG0419@1|root,COG0419@2|Bacteria,1Q57D@1224|Proteobacteria,42NIY@68525|delta/epsilon subdivisions,2YNHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	P-loop containing region of AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_887578_1	1034807.FBFL15_0737	1.69e-07	52.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia,2NSC1@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_887578_2	1137281.D778_01865	8.17e-64	203.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_1564398_1	1394178.AWOO02000026_gene5104	3.73e-08	60.1	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4EHII@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_38765_1	929558.SMGD1_2256	2.17e-131	380.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2YMY3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	hydrogenase expression formation protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_210492_1	1123518.ARWI01000001_gene1310	2.43e-45	167.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,45ZW5@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
k59_210492_2	1168067.JAGP01000001_gene2033	3.26e-42	152.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,461PB@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_995451_1	367737.Abu_1286	6.83e-94	288.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_152741_1	1178825.ALIH01000007_gene1751	1.15e-22	95.9	2E3AK@1|root,32YA3@2|Bacteria,4PQ2A@976|Bacteroidetes,1IKYT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1792441_1	1123228.AUIH01000041_gene2959	3.41e-30	120.0	COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1XRVI@135619|Oceanospirillales	135619|Oceanospirillales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
k59_1792445_1	1121931.AUHG01000012_gene2930	2.63e-116	345.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1HXNP@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_721129_1	411154.GFO_0182	6.81e-88	287.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_1564424_1	323850.Shew_3438	1.59e-33	127.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2QAYJ@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1564424_2	323850.Shew_3439	1.34e-26	107.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2Q8PV@267890|Shewanellaceae	1236|Gammaproteobacteria	U	type II secretion system protein	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1282727_1	411154.GFO_3429	8.67e-24	97.1	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1282727_2	411154.GFO_3430	5.31e-14	68.2	COG1652@1|root,COG1652@2|Bacteria,4NMED@976|Bacteroidetes,1I1AU@117743|Flavobacteriia	976|Bacteroidetes	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
k59_547182_1	1380600.AUYN01000009_gene1765	1.03e-66	225.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_547182_2	1121007.AUML01000042_gene3420	2.45e-48	164.0	2AQB0@1|root,31FH1@2|Bacteria,4NQZH@976|Bacteroidetes,1I3E6@117743|Flavobacteriia,2YHFF@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_547182_3	1349785.BAUG01000032_gene1848	1.65e-07	52.4	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_152781_1	1223410.KN050846_gene909	8.02e-97	293.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_995497_1	572480.Arnit_3031	1.42e-65	205.0	COG5616@1|root,COG5616@2|Bacteria,1QZFF@1224|Proteobacteria,43CIN@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1214920_1	1121931.AUHG01000012_gene2683	1.73e-36	126.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I2CT@117743|Flavobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
k59_1171615_1	345073.VC395_2842	8.44e-37	130.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XWYF@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_212745_1	1121931.AUHG01000016_gene994	8.37e-179	530.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1217017_2	1565129.JSFF01000036_gene1434	5.56e-84	252.0	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,2QBX8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,DUF4124
k59_1680899_1	1137281.D778_00748	9.45e-55	179.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1HWRB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1680899_2	1178825.ALIH01000001_gene2557	2.23e-24	101.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_549101_1	572480.Arnit_0924	1.75e-124	366.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_1680914_1	888059.HMPREF9071_1627	2.04e-06	50.1	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1I2UP@117743|Flavobacteriia,1ES3A@1016|Capnocytophaga	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_325557_1	929558.SMGD1_1857	1.97e-35	128.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2YMCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_325557_2	929558.SMGD1_1855	5.95e-93	283.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_723402_1	313603.FB2170_06645	1.56e-146	425.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes,1IETD@117743|Flavobacteriia,2PIUE@252356|Maribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k59_1343609_1	1294143.H681_07780	8.28e-37	134.0	COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DTW domain containing protein	yfiP	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
k59_438191_1	318167.Sfri_3407	1.3e-15	75.5	COG0524@1|root,COG0524@2|Bacteria,1R52G@1224|Proteobacteria,1RN4W@1236|Gammaproteobacteria,2QEI6@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR,PfkB
k59_438191_2	425104.Ssed_1122	2.19e-31	118.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,1RQ1V@1236|Gammaproteobacteria,2QAPT@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the IUNH family	IUNH	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
k59_1737547_1	1172190.M947_04160	1.28e-161	469.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_212793_1	1565129.JSFF01000008_gene2648	3.19e-65	219.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1SK84@1236|Gammaproteobacteria,2Q97S@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_212793_2	458817.Shal_0110	4.01e-35	123.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RRAN@1236|Gammaproteobacteria,2Q9IA@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdhB	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_1057543_1	929558.SMGD1_2720	4.27e-79	249.0	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_942981_1	1249997.JHZW01000002_gene781	1.69e-34	135.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_889548_1	1565129.JSFF01000001_gene1022	2.12e-112	347.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,2Q8NV@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_1566640_1	411154.GFO_2804	3.04e-43	153.0	COG1292@1|root,COG1292@2|Bacteria,4NEIW@976|Bacteroidetes,1HXKK@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the BCCT transporter (TC 2.A.15) family	opuD	-	-	ko:K02168,ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11,2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_723436_1	326298.Suden_1040	6.17e-48	171.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_1343644_1	1380600.AUYN01000009_gene1798	1.49e-71	227.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_1680972_1	572480.Arnit_0407	3.67e-139	411.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k59_834198_1	502025.Hoch_4284	1.76e-101	314.0	COG2730@1|root,COG2730@2|Bacteria,1PJTY@1224|Proteobacteria,430AX@68525|delta/epsilon subdivisions,2WVW9@28221|Deltaproteobacteria,2Z13Z@29|Myxococcales	28221|Deltaproteobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
k59_664814_1	187272.Mlg_2589	8.45e-98	297.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,1X02P@135613|Chromatiales	135613|Chromatiales	P	NMT1-like family	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_1217111_1	1189619.pgond44_05460	1.21e-28	114.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HYJX@117743|Flavobacteriia,4C2GY@83612|Psychroflexus	976|Bacteroidetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1217111_2	1178825.ALIH01000011_gene88	1.13e-20	88.6	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1115027_1	1121912.AUHD01000001_gene2401	3.94e-39	145.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_1115027_2	1380600.AUYN01000009_gene1365	1.68e-12	66.2	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_776093_1	709032.Sulku_0635	9.42e-15	75.5	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,MCPsignal
k59_776093_2	1537917.JU82_07300	1.04e-10	63.9	COG0745@1|root,COG0745@2|Bacteria,1Q4N0@1224|Proteobacteria,42ZGM@68525|delta/epsilon subdivisions,2YRQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1115028_1	207954.MED92_05268	1.68e-102	299.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,1RPRR@1236|Gammaproteobacteria,1XIIZ@135619|Oceanospirillales	135619|Oceanospirillales	S	Intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_1074975_2	1353276.JADR01000003_gene2682	1.36e-180	526.0	COG3291@1|root,COG3291@2|Bacteria,4PMG1@976|Bacteroidetes,1IKIP@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017
k59_1132117_2	1123518.ARWI01000001_gene1796	0.0	1011.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_2514_1	323850.Shew_0555	3.82e-85	281.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,2Q96K@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	yjeP	-	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel,MscS_TM,MscS_porin
k59_736693_1	1178825.ALIH01000003_gene2221	1.21e-120	357.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1HX67@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
k59_454332_2	1249480.B649_01135	1.33e-47	167.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42SRV@68525|delta/epsilon subdivisions,2YR7J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1244467_1	983544.Lacal_0966	2.21e-38	132.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_1244467_2	1380600.AUYN01000007_gene3185	1.45e-208	581.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1HWZ8@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1244467_3	1178825.ALIH01000003_gene2217	2.54e-114	330.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia	976|Bacteroidetes	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1357612_1	1235798.C817_05737	7.73e-36	135.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_58925_1	1121931.AUHG01000010_gene39	4.55e-99	294.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_340892_1	411154.GFO_0627	1.86e-103	302.0	COG0741@1|root,COG0741@2|Bacteria,4NMIF@976|Bacteroidetes,1I1GE@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan-binding protein LysM	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_680286_1	1380600.AUYN01000009_gene1369	6.47e-85	258.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
k59_680286_2	1380600.AUYN01000009_gene1368	1.01e-126	375.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_1019211_1	1265503.KB905170_gene115	4.35e-118	354.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,1S87U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5,DUF915,LCAT,PGAP1
k59_284790_1	1484460.JSWG01000010_gene3189	2.1e-126	370.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1HWJW@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_284790_2	1380384.JADN01000008_gene1125	2.24e-70	218.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1HXP0@117743|Flavobacteriia	976|Bacteroidetes	Q	Organic solvent ABC transporter ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_115415_1	1449351.RISW2_17000	4.77e-06	51.6	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,4KNFF@93682|Roseivivax	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	ctrA	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_171908_1	59538.XP_005972045.1	5.34e-47	167.0	COG1012@1|root,KOG2456@2759|Eukaryota,38CW8@33154|Opisthokonta,3BDR1@33208|Metazoa,3CZ4X@33213|Bilateria,47ZQK@7711|Chordata,497P7@7742|Vertebrata,3J5DC@40674|Mammalia,4J7KY@91561|Cetartiodactyla	33208|Metazoa	C	Aldehyde dehydrogenase 3 family, member A2	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_680290_1	411154.GFO_3168	4.59e-176	494.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1HWPD@117743|Flavobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	tdo2	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
k59_680290_2	411154.GFO_3169	2.45e-78	239.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_1527412_1	1123518.ARWI01000001_gene1550	2.76e-113	338.0	COG1519@1|root,COG1519@2|Bacteria,1RBYU@1224|Proteobacteria,1S5BN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_1357634_1	929558.SMGD1_1509	6.27e-28	105.0	2AIVF@1|root,319NT@2|Bacteria,1Q3D4@1224|Proteobacteria,42X4I@68525|delta/epsilon subdivisions,2YQUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Flagellar FliJ protein	-	-	-	-	-	-	-	-	-	-	-	-	FliJ
k59_1357634_2	1172190.M947_05910	5.27e-30	112.0	COG3334@1|root,COG3334@2|Bacteria,1Q9SM@1224|Proteobacteria,42TJV@68525|delta/epsilon subdivisions,2YPUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PDP protein	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
k59_736737_1	1218074.BAXZ01000020_gene3945	4.56e-163	463.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,1JZN1@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1640649_1	1123514.KB905899_gene1515	8.58e-103	321.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_228355_1	572480.Arnit_2174	1.67e-09	55.8	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2YPE3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_228355_2	572480.Arnit_2173	1.21e-82	248.0	COG0745@1|root,COG0745@2|Bacteria,1Q99R@1224|Proteobacteria,42SS4@68525|delta/epsilon subdivisions,2YPE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_510162_1	1123514.KB905899_gene1724	1.09e-95	283.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,460TJ@72273|Thiotrichales	72273|Thiotrichales	L	NUDIX domain	-	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_567236_1	425104.Ssed_1988	1.34e-34	131.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,2Q9VP@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM Peptidoglycan-binding LysM	mltD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_2574_1	497321.C664_17642	5.39e-05	48.5	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KUHV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_228377_1	411154.GFO_2183	7.66e-122	371.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1640683_1	90814.KL370891_gene29	1.05e-106	319.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,46026@72273|Thiotrichales	72273|Thiotrichales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1188642_1	1121931.AUHG01000011_gene1837	4.79e-13	67.4	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1HXXI@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1188642_2	1121931.AUHG01000011_gene1838	7.69e-76	231.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1I0RX@117743|Flavobacteriia	976|Bacteroidetes	M	serine threonine protein kinase	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
k59_284842_1	1123514.KB905899_gene600	4.48e-59	203.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,460CR@72273|Thiotrichales	72273|Thiotrichales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_1755223_2	1121931.AUHG01000012_gene2494	2.6e-87	260.0	COG3952@1|root,COG3952@2|Bacteria,4NH8Q@976|Bacteroidetes,1HYST@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM lipid A biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
k59_1585791_1	1172190.M947_10240	3.96e-86	263.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2YNIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1085 Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_342407_1	90813.JQMT01000001_gene1764	6.73e-27	108.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria,461VV@72273|Thiotrichales	72273|Thiotrichales	P	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_342407_2	1123518.ARWI01000001_gene1088	4.48e-187	520.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,461Q0@72273|Thiotrichales	72273|Thiotrichales	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_568701_1	926559.JoomaDRAFT_2180	2.76e-57	191.0	COG1462@1|root,COG1462@2|Bacteria,4NEH1@976|Bacteroidetes,1HXH5@117743|Flavobacteriia	976|Bacteroidetes	M	Curli production assembly	csgG	-	-	ko:K06214	-	-	-	-	ko00000,ko02044	-	-	-	CsgG,OMP_b-brl
k59_568701_2	1250278.JQNQ01000001_gene673	3.37e-39	134.0	2DEP1@1|root,32U3R@2|Bacteria,4NQDA@976|Bacteroidetes,1I328@117743|Flavobacteriia	976|Bacteroidetes	S	Curli assembly protein CsgF	-	-	-	ko:K04338	-	-	-	-	ko00000,ko02044	-	-	-	CsgF
k59_116955_1	1279017.AQYJ01000027_gene1962	7.6e-50	176.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46A3P@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8
k59_568707_1	1387312.BAUS01000007_gene2389	1.19e-47	181.0	COG2199@1|root,COG3290@1|root,COG3447@1|root,COG3614@1|root,COG2199@2|Bacteria,COG3290@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,1RGCV@1224|Proteobacteria,2VMY7@28216|Betaproteobacteria,2KMN2@206350|Nitrosomonadales	206350|Nitrosomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,MASE1,PAS
k59_738407_1	1565314.OA34_06745	1.87e-07	50.4	COG2204@1|root,COG2204@2|Bacteria,1RHEG@1224|Proteobacteria,42UQT@68525|delta/epsilon subdivisions,2YPX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_738407_2	326298.Suden_0283	2.42e-59	197.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,42PPM@68525|delta/epsilon subdivisions,2YN9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	tlpD	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1359078_1	1380600.AUYN01000009_gene2128	3.62e-213	614.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1359078_2	313594.PI23P_10565	1.2e-19	83.2	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1I2YQ@117743|Flavobacteriia,3VWQF@52959|Polaribacter	976|Bacteroidetes	M	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_4047_1	1185766.DL1_06230	1.4e-107	322.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2XN02@285107|Thioclava	28211|Alphaproteobacteria	S	Putative modulator of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1076558_1	1121931.AUHG01000016_gene1013	6.39e-93	286.0	COG2031@1|root,COG2031@2|Bacteria,4NIRP@976|Bacteroidetes,1HWM3@117743|Flavobacteriia	976|Bacteroidetes	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
k59_1528919_1	1038860.AXAP01000075_gene7048	2.75e-79	241.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,3JUMA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_30645	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_456145_1	1121931.AUHG01000016_gene1007	1.17e-10	58.5	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,1I4Q6@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_456145_2	411154.GFO_0733	2.26e-23	95.9	COG0589@1|root,COG0589@2|Bacteria,4NE48@976|Bacteroidetes,1HXRC@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1472257_1	1380600.AUYN01000006_gene478	1.61e-68	213.0	COG2885@1|root,COG2885@2|Bacteria,4NMF0@976|Bacteroidetes,1IJWQ@117743|Flavobacteriia	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_60637_1	1121931.AUHG01000010_gene533	3.17e-140	397.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_511949_1	644076.SCH4B_4375	2.64e-06	47.8	2AJ1X@1|root,319K5@2|Bacteria,1RK0X@1224|Proteobacteria,2UKUD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2829)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2829
k59_738434_1	1049564.TevJSym_aa00960	1.85e-62	215.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1J4Y6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_1359105_1	997352.HMPREF9419_0433	6.25e-22	94.7	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_907835_1	598659.NAMH_1605	3.99e-40	148.0	COG1887@1|root,COG1887@2|Bacteria,1MYNJ@1224|Proteobacteria,42T8Z@68525|delta/epsilon subdivisions,2YQI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
k59_1133698_1	929558.SMGD1_0328	9.52e-121	353.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2YN3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1472287_1	555500.I215_04755	6.47e-30	114.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia	976|Bacteroidetes	S	Acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1472287_2	1380600.AUYN01000009_gene1008	1.12e-152	431.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1HX38@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_1472287_3	1120951.AUBG01000012_gene1668	7.06e-09	55.8	COG2267@1|root,COG2267@2|Bacteria,4PKJZ@976|Bacteroidetes,1IJBC@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_60676_1	1121931.AUHG01000012_gene2701	9.22e-101	314.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_511972_2	1298858.AUEL01000029_gene66	1.42e-141	424.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,43K78@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
k59_625492_1	1137281.D778_01670	4.05e-82	245.0	COG1974@1|root,COG1974@2|Bacteria,4NQXK@976|Bacteroidetes,1I2WU@117743|Flavobacteriia	976|Bacteroidetes	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
k59_625492_2	1121887.AUDK01000017_gene39	2.31e-158	461.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia,2NUAJ@237|Flavobacterium	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_1698684_1	1123518.ARWI01000001_gene108	3.59e-123	358.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,45ZR0@72273|Thiotrichales	72273|Thiotrichales	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_1133725_1	572480.Arnit_0609	1.1e-146	414.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42MTC@68525|delta/epsilon subdivisions,2YMSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cosR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1021041_2	746697.Aeqsu_1000	7.48e-71	227.0	COG2250@1|root,COG2250@2|Bacteria,4NM94@976|Bacteroidetes,1I1CK@117743|Flavobacteriia	976|Bacteroidetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1698696_1	1123514.KB905903_gene390	6.68e-145	424.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,460P1@72273|Thiotrichales	72273|Thiotrichales	FP	Belongs to the GppA Ppx family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_456222_1	1041146.ATZB01000058_gene4176	8.73e-60	202.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8
k59_60708_1	411154.GFO_2659	4.16e-18	81.6	COG3129@1|root,COG3129@2|Bacteria,4NF3Z@976|Bacteroidetes,1HWRU@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
k59_60708_2	411154.GFO_2658	7.25e-88	271.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,1HXC8@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1472336_1	929558.SMGD1_0543	3.46e-109	333.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_682313_1	1380600.AUYN01000009_gene1773	1.55e-83	259.0	COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,1HYMN@117743|Flavobacteriia	976|Bacteroidetes	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k59_1189644_1	1565129.JSFF01000002_gene3432	3.38e-119	365.0	COG0247@1|root,COG0277@1|root,COG1150@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1150@2|Bacteria,1MU6Y@1224|Proteobacteria,1RM7Z@1236|Gammaproteobacteria,2QAKZ@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	lldE	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
k59_456250_1	292415.Tbd_0983	1.76e-21	99.4	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_568827_1	1123518.ARWI01000001_gene1346	1.55e-67	226.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,PAS_4
k59_512030_1	1178825.ALIH01000013_gene504	2.27e-100	299.0	COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1HX87@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_1698737_1	944546.ABED_0011	3.91e-23	93.6	COG3585@1|root,COG3585@2|Bacteria,1N06J@1224|Proteobacteria,42U4N@68525|delta/epsilon subdivisions,2YQ5D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
k59_1698737_2	1355374.JARU01000020_gene954	2.1e-49	164.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_117079_1	1121931.AUHG01000010_gene309	2.98e-168	483.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
k59_117079_2	1121931.AUHG01000010_gene310	4.06e-21	89.4	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
k59_4164_1	296591.Bpro_1882	2.05e-62	197.0	COG1045@1|root,COG1045@2|Bacteria	2|Bacteria	E	serine acetyltransferase	-	-	2.3.1.30	ko:K00640,ko:K08699	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_1642518_1	944547.ABLL_0894	9.55e-12	67.8	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2YRDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Putative exonuclease SbcCD, C subunit	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_682338_1	411154.GFO_3204	6.57e-67	209.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,1HXM3@117743|Flavobacteriia	976|Bacteroidetes	P	divalent heavy-metal cations transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_1319403_1	746697.Aeqsu_0254	2.11e-80	251.0	COG2982@1|root,COG2982@2|Bacteria,4NIE2@976|Bacteroidetes,1HZC9@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1200135_1	929558.SMGD1_1981	1.34e-83	253.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2YR7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k59_866372_1	1380600.AUYN01000009_gene1982	1.17e-91	284.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
k59_1714252_1	391603.FBALC1_09987	1.08e-21	89.7	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia	976|Bacteroidetes	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_1714252_2	1178825.ALIH01000002_gene918	1.07e-103	305.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1I1DS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k59_301936_1	1121875.KB907546_gene2674	3.26e-152	433.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
k59_301936_2	1121875.KB907546_gene2673	1.69e-222	624.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_301936_3	1121875.KB907546_gene2672	9.26e-103	308.0	2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1488112_1	177437.HRM2_01270	9.78e-31	126.0	COG0834@1|root,COG2202@1|root,COG4191@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42RZ2@68525|delta/epsilon subdivisions,2WP0V@28221|Deltaproteobacteria,2MMQI@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,SBP_bac_3
k59_1488117_1	1027273.GZ77_07755	6.39e-60	207.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XH2S@135619|Oceanospirillales	135619|Oceanospirillales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_189356_1	1123514.KB905899_gene1781	6.11e-114	335.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales	72273|Thiotrichales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_189356_2	1123514.KB905899_gene1780	4.24e-152	436.0	COG3111@1|root,COG3111@2|Bacteria,1MU8B@1224|Proteobacteria,1S1UJ@1236|Gammaproteobacteria,460U6@72273|Thiotrichales	72273|Thiotrichales	S	short chain amide porin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131712_1	863365.XHC_0899	5.75e-08	53.9	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1X3N9@135614|Xanthomonadales	135614|Xanthomonadales	HL	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4,TMP-TENI
k59_131712_2	67352.JODS01000001_gene336	2.96e-28	112.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
k59_1430822_1	1178825.ALIH01000003_gene2019	6.18e-48	159.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1430822_2	1380600.AUYN01000007_gene3400	1.33e-99	293.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1I1C6@117743|Flavobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1430822_3	1347342.BN863_1890	1.73e-40	147.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1261627_1	1121931.AUHG01000010_gene461	7.4e-81	258.0	COG0657@1|root,COG4677@1|root,COG0657@2|Bacteria,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,1HWVG@117743|Flavobacteriia	976|Bacteroidetes	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Pectinesterase
k59_1149683_2	1165841.SULAR_03492	2.24e-13	66.6	COG2128@1|root,COG2128@2|Bacteria,1PZ9M@1224|Proteobacteria,42PYF@68525|delta/epsilon subdivisions,2YNK8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1093317_1	1123392.AQWL01000004_gene2803	1.04e-37	144.0	COG4264@1|root,COG4264@2|Bacteria,1NEZU@1224|Proteobacteria,2WE9N@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	IucA / IucC family	-	-	-	-	-	-	-	-	-	-	-	-	FhuF,IucA_IucC
k59_1773018_1	929558.SMGD1_0558	1.08e-103	318.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1149684_1	1442598.JABW01000031_gene1233	2.15e-16	78.2	COG5002@1|root,COG5002@2|Bacteria,1QUJ9@1224|Proteobacteria,42MEB@68525|delta/epsilon subdivisions,2YMXI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1149684_2	944547.ABLL_1205	2.96e-58	184.0	COG1309@1|root,COG1309@2|Bacteria,1RDIP@1224|Proteobacteria,42XZ0@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
k59_247985_1	1123518.ARWI01000001_gene2031	1.16e-149	436.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,460A8@72273|Thiotrichales	72273|Thiotrichales	NU	Secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1375829_1	1502724.FF80_00924	6.99e-61	210.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3N65D@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_247990_1	1123517.JOMR01000001_gene1711	1.54e-63	220.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461MN@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_529630_1	1123514.KB905899_gene1686	1.83e-30	120.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,460JU@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
k59_529630_2	1123517.JOMR01000001_gene536	1.07e-05	46.2	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,460NU@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_754835_1	326298.Suden_0032	2.9e-24	100.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2YN81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	flgE	GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flagellin_IN,Flg_bb_rod,Flg_bbr_C
k59_754835_2	929558.SMGD1_1290	4.64e-82	253.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_20133_1	1005048.CFU_2557	2.28e-69	220.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,475QG@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	amino acid transport system, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_1263682_1	411154.GFO_2364	4.23e-37	137.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA
k59_1263682_2	411154.GFO_2363	3.19e-120	343.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia	976|Bacteroidetes	I	Isopentenyl-diphosphate delta-isomerase	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
k59_868546_2	1123368.AUIS01000018_gene715	5.15e-24	102.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,1SBXG@1236|Gammaproteobacteria,2NC91@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_813005_1	1123517.JOMR01000001_gene519	2.82e-28	108.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,460NP@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_813005_2	90813.JQMT01000001_gene336	1.2e-87	263.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,45ZP8@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_1149704_1	1336233.JAEH01000004_gene1568	6.64e-60	186.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR3Q@1236|Gammaproteobacteria,2QC7D@267890|Shewanellaceae	1236|Gammaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_1149704_2	1111728.ATYS01000128_gene3518	3.59e-52	174.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_868551_1	985255.APHJ01000018_gene3044	3.65e-73	244.0	COG0732@1|root,COG1002@1|root,COG0732@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia	976|Bacteroidetes	L	Restriction	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
k59_1038069_1	1283300.ATXB01000001_gene1125	2.15e-29	114.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1XDPB@135618|Methylococcales	135618|Methylococcales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1038069_2	317025.Tcr_1809	1.26e-40	134.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,46141@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_1038069_3	90814.KL370891_gene1765	1.48e-43	145.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,46109@72273|Thiotrichales	72273|Thiotrichales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_1375866_1	563040.Saut_1449	2.7e-69	214.0	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1263723_1	1565129.JSFF01000003_gene2190	1.06e-84	262.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,2QA2W@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_1659854_1	1380600.AUYN01000001_gene2492	4.22e-32	121.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1I0BY@117743|Flavobacteriia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
k59_304086_1	880073.Calab_1761	2.23e-29	119.0	COG3696@1|root,COG3696@2|Bacteria,2NP07@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran,OEP
k59_304086_2	985255.APHJ01000017_gene2148	1.17e-18	87.8	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia,2P7GQ@244698|Gillisia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_191441_1	1123518.ARWI01000001_gene408	1.62e-73	229.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,4614Z@72273|Thiotrichales	72273|Thiotrichales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_191441_2	1123518.ARWI01000001_gene409	5.19e-162	460.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,45ZSI@72273|Thiotrichales	72273|Thiotrichales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1093392_2	411154.GFO_3398	1.95e-81	244.0	COG1510@1|root,COG1510@2|Bacteria,4NSVR@976|Bacteroidetes,1I1BX@117743|Flavobacteriia	976|Bacteroidetes	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_473927_1	313603.FB2170_14818	4.79e-146	427.0	COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133692_1	411154.GFO_0149	9.44e-109	335.0	COG2202@1|root,COG3452@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3452@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,PAS_3,PAS_9
k59_1432784_1	1406840.Q763_09725	1.01e-217	651.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,1HZXU@117743|Flavobacteriia,2NTUX@237|Flavobacterium	976|Bacteroidetes	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
k59_20205_1	572480.Arnit_1994	1.61e-74	238.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2YMZS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.4	ko:K00382,ko:K21739	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_304107_1	1408473.JHXO01000013_gene609	2.64e-46	164.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,2FN4C@200643|Bacteroidia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_304107_2	525373.HMPREF0766_12618	1.24e-07	54.3	COG0845@1|root,COG2608@1|root,COG0845@2|Bacteria,COG2608@2|Bacteria,4NG8S@976|Bacteroidetes,1IPFI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HMA,HlyD_D23
k59_529722_1	945713.IALB_0015	3.58e-73	245.0	COG1197@1|root,COG1197@2|Bacteria	2|Bacteria	L	transcription-coupled nucleotide-excision repair, DNA damage recognition	mfd	-	2.4.1.129,3.4.16.4	ko:K03723,ko:K05365	ko00550,ko03420,map00550,map03420	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011,ko03400	-	GT51	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1490390_2	1249480.B649_11270	6.2e-54	176.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133703_1	1123234.AUKI01000004_gene59	2.08e-84	271.0	COG0362@1|root,COG3265@1|root,COG0362@2|Bacteria,COG3265@2|Bacteria,4NG05@976|Bacteroidetes,1HXYX@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2,SKI
k59_1490394_1	1123518.ARWI01000001_gene285	8.14e-244	698.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,1RYNI@1236|Gammaproteobacteria,461UP@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_1149794_1	709032.Sulku_1992	1.28e-06	47.4	COG3370@1|root,COG3370@2|Bacteria,1N27G@1224|Proteobacteria,42UAJ@68525|delta/epsilon subdivisions,2YPZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_1149794_2	326298.Suden_1510	7.06e-91	278.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_473953_2	90814.KL370891_gene1826	3.69e-31	116.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RPGM@1236|Gammaproteobacteria,460YR@72273|Thiotrichales	72273|Thiotrichales	IQ	FolM Alternative dihydrofolate reductase 1	-	-	1.5.1.3,1.5.1.50	ko:K13938	ko00670,ko00790,ko01100,map00670,map00790,map01100	-	R00936,R00939,R11019	RC00109,RC03327	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
k59_529760_1	1114970.PSF113_0793	9.05e-38	147.0	COG3210@1|root,COG5585@1|root,COG3210@2|Bacteria,COG5585@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN
k59_1263790_1	1172190.M947_10245	3.05e-140	417.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,42M42@68525|delta/epsilon subdivisions,2YMAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
k59_133729_1	1484460.JSWG01000015_gene1232	1.15e-176	530.0	COG0308@1|root,COG0842@1|root,COG0308@2|Bacteria,COG0842@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k59_1716440_1	1347342.BN863_2810	5.27e-67	206.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_1716440_2	1392490.JHZX01000001_gene1212	3.35e-06	48.1	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I4IY@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
k59_1038172_1	235279.HH_1845	1.28e-44	157.0	COG4974@1|root,COG4974@2|Bacteria,1R440@1224|Proteobacteria,43AEK@68525|delta/epsilon subdivisions,2YT19@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
k59_191508_1	929558.SMGD1_1226	1.66e-94	303.0	COG2319@1|root,COG2319@2|Bacteria,1Q4KY@1224|Proteobacteria,42ZEF@68525|delta/epsilon subdivisions,2YR4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1545378_1	1137281.D778_02353	1.28e-59	184.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,1I4M9@117743|Flavobacteriia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_1604157_1	1121127.JAFA01000001_gene673	2.12e-20	88.2	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKD3@28216|Betaproteobacteria,1K0J2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF2063,DUF692
k59_1604157_2	1500894.JQNN01000001_gene229	1.24e-11	63.2	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2VWC8@28216|Betaproteobacteria,478B2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
k59_416947_1	1121931.AUHG01000011_gene2402	1.09e-106	322.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_813166_1	1137281.D778_00384	8.51e-53	167.0	COG2388@1|root,COG2388@2|Bacteria,4NVBP@976|Bacteroidetes,1I41N@117743|Flavobacteriia	976|Bacteroidetes	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
k59_813166_2	1380600.AUYN01000009_gene1604	5.54e-113	328.0	COG1073@1|root,COG1073@2|Bacteria,4NFVJ@976|Bacteroidetes,1HXBR@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
k59_813166_3	1380600.AUYN01000009_gene1605	5.13e-24	99.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_1432852_1	1123518.ARWI01000001_gene1325	2.04e-90	280.0	COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,4636N@72273|Thiotrichales	72273|Thiotrichales	KLT	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Sel1
k59_248149_1	1168067.JAGP01000001_gene501	8.61e-59	201.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,460M8@72273|Thiotrichales	72273|Thiotrichales	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_191532_1	1380600.AUYN01000001_gene2500	2.85e-167	471.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_191532_2	1380600.AUYN01000001_gene2501	7.23e-84	251.0	2E7SQ@1|root,3327W@2|Bacteria,4NUWY@976|Bacteroidetes,1I5CR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_924390_1	944547.ABLL_2526	4.36e-79	237.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2YNX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_1604192_1	746697.Aeqsu_3178	2.51e-107	320.0	COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes,1HX5I@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1263826_1	1123514.KB905899_gene1583	1.9e-96	285.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,460F5@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_1263826_2	1123518.ARWI01000001_gene790	4.99e-86	257.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,460XQ@72273|Thiotrichales	72273|Thiotrichales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1263826_3	1123518.ARWI01000001_gene791	3.04e-42	139.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_1376014_1	598659.NAMH_1606	1.63e-62	209.0	COG1028@1|root,COG1211@1|root,COG1028@2|Bacteria,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,42RJ4@68525|delta/epsilon subdivisions,2YRGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.405,2.7.7.40	ko:K21681	ko00040,ko01100,map00040,map01100	-	R01525,R02921	RC00002,RC00089	ko00000,ko00001,ko01000	-	-	-	IspD,adh_short
k59_586088_1	1123514.KB905899_gene782	7.27e-101	301.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,4609E@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_586088_2	90814.KL370891_gene947	2.2e-24	92.8	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,4616D@72273|Thiotrichales	72273|Thiotrichales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_78713_1	411154.GFO_2138	6.97e-15	73.6	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	GO:0001871,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0004185,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0009987,GO:0010467,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030246,GO:0030247,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044421,GO:0051604,GO:0070008,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:2001070	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1568935_1	411154.GFO_3483	8.29e-117	348.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_156908_1	1380600.AUYN01000001_gene2559	2.09e-102	298.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
k59_156908_2	504487.JCM19302_1971	4.56e-33	121.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia	976|Bacteroidetes	S	NADP oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
k59_778798_1	1121931.AUHG01000017_gene1559	6.93e-152	443.0	COG3930@1|root,COG3930@2|Bacteria,4NG5D@976|Bacteroidetes,1HZIT@117743|Flavobacteriia	976|Bacteroidetes	E	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
k59_215248_1	1469557.JSWF01000032_gene3124	1.66e-155	441.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia	976|Bacteroidetes	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_215248_2	1380600.AUYN01000009_gene1142	2.61e-07	50.8	COG0597@1|root,COG0597@2|Bacteria,4NNP3@976|Bacteroidetes,1I23N@117743|Flavobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_328049_1	435908.IDSA_03225	3.09e-55	181.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,2QFMG@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO1056	Acetyltransf_11,Hexapep
k59_156922_1	90814.KL370891_gene1851	6.03e-88	265.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,46006@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_156922_2	1123518.ARWI01000001_gene1785	6.82e-98	286.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,460PP@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_156922_3	90814.KL370891_gene1853	5.1e-21	91.3	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,46070@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_607652_1	391598.FBBAL38_04945	1.26e-94	285.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1346257_1	323850.Shew_3752	7.24e-86	266.0	COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,1RNBM@1236|Gammaproteobacteria,2Q8PU@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	ybdG	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0016020,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0071944,GO:0104004	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
k59_440350_1	398579.Spea_1999	7.06e-74	228.0	COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,1RM8J@1236|Gammaproteobacteria,2Q9N8@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_551628_1	1202532.FF52_16938	9.42e-105	320.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia,2NV7Y@237|Flavobacterium	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_1219610_1	1502852.FG94_00169	2.26e-67	224.0	COG4625@1|root,COG4625@2|Bacteria,1R600@1224|Proteobacteria	1224|Proteobacteria	S	Rhamnogalacturonan lyase B, N-terminal	rhgB	-	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
k59_725930_1	929558.SMGD1_2686	6.5e-57	188.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_328093_1	945713.IALB_1910	9.02e-29	114.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5,Acyl_transf_3,DUF1624
k59_328093_2	945713.IALB_1909	1.43e-12	67.0	COG2255@1|root,COG2255@2|Bacteria	2|Bacteria	L	four-way junction helicase activity	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_607687_1	1191523.MROS_2015	1.27e-07	58.2	COG0642@1|root,COG0745@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_328113_2	1380600.AUYN01000009_gene1584	4.56e-67	226.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1174255_1	1185766.DL1_00735	1.95e-126	372.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,2XMU0@285107|Thioclava	28211|Alphaproteobacteria	O	-cysteine	sufB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_102570_1	357804.Ping_2906	4.1e-65	200.0	COG3439@1|root,COG3439@2|Bacteria,1RHJQ@1224|Proteobacteria,1S5ZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_102570_2	443152.MDG893_08751	1.17e-36	132.0	COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria,1SIPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_497419_1	425104.Ssed_4138	8.45e-35	137.0	COG0354@1|root,COG2304@1|root,COG2931@1|root,COG0354@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2Q9AA@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Outer membrane adhesin like proteiin	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HCBP_related,HemolysinCabind
k59_551682_1	1120951.AUBG01000019_gene1685	3.42e-117	343.0	COG0300@1|root,COG0300@2|Bacteria,4NIAI@976|Bacteroidetes,1HWTS@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_551682_2	1178825.ALIH01000020_gene2715	1.43e-118	349.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1346330_1	572480.Arnit_1717	8.02e-95	286.0	COG0770@1|root,COG0770@2|Bacteria,1Q5GZ@1224|Proteobacteria,42RQ8@68525|delta/epsilon subdivisions,2YP4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_440411_1	867900.Celly_0098	2.53e-48	174.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia,1F876@104264|Cellulophaga	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_1514973_1	1121931.AUHG01000010_gene370	7.61e-158	451.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1HWXE@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1514973_2	411154.GFO_3384	1.14e-27	105.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1HWRQ@117743|Flavobacteriia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_1346333_1	326298.Suden_1136	3.13e-53	184.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42RCJ@68525|delta/epsilon subdivisions,2YNX9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
k59_1000378_1	563040.Saut_1856	1.25e-18	84.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_1000378_2	929558.SMGD1_1673	6.95e-120	348.0	COG2214@1|root,COG2214@2|Bacteria,1QV0K@1224|Proteobacteria,42RGB@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
k59_440418_1	929558.SMGD1_0752	9.26e-77	232.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2YP7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_440418_2	563040.Saut_1654	1.32e-92	274.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2YT8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_778925_1	1565129.JSFF01000012_gene576	9.95e-74	224.0	2CIG1@1|root,33MZH@2|Bacteria,1NPWM@1224|Proteobacteria,1SHNF@1236|Gammaproteobacteria,2QBZE@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_102601_1	983544.Lacal_2650	5.76e-133	396.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_726002_1	323850.Shew_3448	1.47e-86	261.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,2QAJ9@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
k59_157024_1	1250232.JQNJ01000001_gene3000	2.75e-74	248.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1219715_1	1137281.D778_02761	6.68e-105	308.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,1HYHS@117743|Flavobacteriia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_1219715_2	1137281.D778_02762	3.64e-55	179.0	COG1946@1|root,COG1946@2|Bacteria,4NEY8@976|Bacteroidetes,1HZXI@117743|Flavobacteriia	976|Bacteroidetes	I	Thioesterase-like superfamily	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
k59_891735_1	1172190.M947_03860	8.15e-60	186.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_891735_2	929558.SMGD1_1923	3.67e-45	157.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1797472_1	411154.GFO_2553	2.46e-83	254.0	COG0589@1|root,COG0589@2|Bacteria,4NER9@976|Bacteroidetes,1HYXH@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_945378_1	1123514.KB905899_gene2040	1.51e-72	230.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,460PI@72273|Thiotrichales	72273|Thiotrichales	H	HemY protein N-terminus	-	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
k59_328194_1	497321.C664_02710	2.03e-57	199.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KUIP@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_667483_1	929556.Solca_1036	1.26e-05	47.8	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_726058_1	1380384.JADN01000008_gene1097	3.53e-119	373.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_270639_1	929558.SMGD1_2867	2.27e-43	147.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_270639_2	1172190.M947_01715	1.27e-18	86.7	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_42973_1	865937.Gilli_1039	2.95e-95	287.0	COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,1HZTF@117743|Flavobacteriia,2P7CG@244698|Gillisia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.183,3.2.1.184	ko:K08068,ko:K18429	ko00520,map00520	-	R10187	RC00005,RC00288	ko00000,ko00001,ko01000	-	-	-	Epimerase_2
k59_667542_1	1121931.AUHG01000010_gene438	7.54e-175	501.0	COG0702@1|root,COG0702@2|Bacteria,4NG5U@976|Bacteroidetes,1I0T9@117743|Flavobacteriia	976|Bacteroidetes	GM	PFAM SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_667557_1	563040.Saut_0666	1.39e-51	167.0	2BR51@1|root,32K31@2|Bacteria,1Q8HX@1224|Proteobacteria,433KM@68525|delta/epsilon subdivisions,2YSI4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_667557_2	563040.Saut_0667	1.91e-26	100.0	COG3018@1|root,COG3018@2|Bacteria,1RGG9@1224|Proteobacteria,42P0S@68525|delta/epsilon subdivisions,2YQJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	(Lipo)protein	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k59_1174428_1	1356852.N008_09935	4.13e-74	248.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,47K29@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_215512_1	1121931.AUHG01000011_gene2398	2.15e-108	324.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY1Z@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
k59_1000531_1	1005999.GLGR_2217	1.44e-15	81.6	COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell	thiP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	iAPECO1_1312.APECO1_1915,iECIAI1_1343.ECIAI1_0067,iECO103_1326.ECO103_0068,iECO111_1330.ECO111_0069,iECO26_1355.ECO26_0069,iECOK1_1307.ECOK1_0068,iECS88_1305.ECS88_0072,iECSE_1348.ECSE_0067,iECUMN_1333.ECUMN_0068,iPC815.YPO0521,iSF_1195.SF0062,iSFxv_1172.SFxv_0064,iS_1188.S0064,iUMN146_1321.UM146_23130,iUTI89_1310.UTI89_C0075	BPD_transp_1
k59_1740613_2	1123517.JOMR01000001_gene1941	1.72e-41	143.0	2B6WS@1|root,31ZWK@2|Bacteria,1RCZJ@1224|Proteobacteria,1S3NQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1515147_1	572480.Arnit_1865	1.06e-68	214.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2YNS5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_1515147_2	572480.Arnit_1869	2.55e-15	72.8	28WAS@1|root,2ZIB8@2|Bacteria,1NBB7@1224|Proteobacteria,42P2G@68525|delta/epsilon subdivisions,2YNQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1346511_1	1178825.ALIH01000019_gene1234	2.73e-17	82.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_1346511_2	1469557.JSWF01000035_gene908	1.96e-48	161.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_157147_1	1123514.KB905899_gene1005	3.87e-42	144.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,460XX@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM nudix-type nucleoside diphosphatase, YffH AdpP family	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_157147_2	717772.THIAE_04955	3.35e-15	72.8	2DC5X@1|root,2ZD0W@2|Bacteria,1P8T3@1224|Proteobacteria,1SW4N@1236|Gammaproteobacteria,46368@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_779150_1	572480.Arnit_2236	2.1e-55	182.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YN0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_779150_2	572480.Arnit_2235	9.57e-50	167.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1455985_1	1123228.AUIH01000004_gene1123	9.32e-28	115.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XIW5@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM,TPR_19
k59_1569213_1	709032.Sulku_1839	7.46e-146	426.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_945513_1	1123514.KB905899_gene1398	7.8e-61	199.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,4606R@72273|Thiotrichales	72273|Thiotrichales	L	ATPase (AAA	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_945513_2	90814.KL370891_gene737	1.23e-70	214.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,460WA@72273|Thiotrichales	72273|Thiotrichales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_215605_1	720554.Clocl_3012	3.49e-40	144.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,3WGTY@541000|Ruminococcaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_102852_1	1123514.KB905901_gene5	7.63e-85	264.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
k59_607960_1	1137281.D778_01199	2.15e-124	367.0	COG1538@1|root,COG1538@2|Bacteria,4NE4S@976|Bacteroidetes,1HXG4@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1626206_1	929558.SMGD1_0081	2.49e-104	312.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2YNFC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1569266_1	411154.GFO_0298	3.88e-42	140.0	2DNW5@1|root,32ZGI@2|Bacteria,4NT26@976|Bacteroidetes,1I423@117743|Flavobacteriia	976|Bacteroidetes	S	Rho termination factor	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
k59_1569266_2	411154.GFO_0299	1.08e-76	234.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,1HZ9G@117743|Flavobacteriia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
k59_1797709_1	1123518.ARWI01000001_gene1852	3.23e-39	142.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6
k59_1626214_1	1123518.ARWI01000001_gene1441	3.43e-135	403.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein Ccs1 ResB	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_667701_1	411154.GFO_3635	1.15e-90	270.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,1HYHS@117743|Flavobacteriia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_782028_3	1380380.JIAX01000008_gene2015	3.54e-08	53.9	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroF	GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
k59_894258_1	497321.C664_14529	5.42e-137	403.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VHP4@28216|Betaproteobacteria,2KUSH@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_385953_1	1121931.AUHG01000019_gene3066	1.43e-07	51.6	2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
k59_385953_2	411154.GFO_2934	7.42e-55	182.0	COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes,1HX5I@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1003244_1	1123367.C666_07075	6.11e-61	204.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,2KUSA@206389|Rhodocyclales	206389|Rhodocyclales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_1401664_1	411154.GFO_1980	8.59e-87	283.0	COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,4PMSQ@976|Bacteroidetes,1HZN0@117743|Flavobacteriia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,PAS_9,Response_reg
k59_1517882_1	367737.Abu_0384	1.36e-14	72.8	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1517882_2	572480.Arnit_0642	5.54e-78	235.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_1686658_1	1336233.JAEH01000006_gene2277	1.16e-105	315.0	COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,2Q9EP@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle	rsmC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
k59_965402_1	1120966.AUBU01000008_gene2397	7.81e-157	457.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1756432_1	225849.swp_0178	2.62e-122	365.0	COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,1RYUG@1236|Gammaproteobacteria,2Q9QW@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_61823_1	1123518.ARWI01000001_gene467	5.94e-184	515.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,461MP@72273|Thiotrichales	72273|Thiotrichales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_61823_2	1123518.ARWI01000001_gene468	3.02e-114	338.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,46248@72273|Thiotrichales	72273|Thiotrichales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
k59_570022_2	929558.SMGD1_2210	1.3e-67	224.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_1022203_1	1168067.JAGP01000001_gene1820	2.09e-19	87.4	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales	1224|Proteobacteria	P	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_851866_1	643867.Ftrac_1528	4.58e-80	247.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,47JZR@768503|Cytophagia	976|Bacteroidetes	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_683461_1	1380600.AUYN01000009_gene1834	1.3e-172	494.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_683461_2	1347342.BN863_22340	2.85e-19	80.9	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1I5AD@117743|Flavobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
k59_1473499_1	1380600.AUYN01000006_gene701	1.97e-170	493.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,1HZ2A@117743|Flavobacteriia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174963_2	425104.Ssed_2115	3.7e-28	111.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,2QA3T@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1643590_1	1449347.JQLN01000005_gene4178	2.51e-16	78.2	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,2M1GQ@2063|Kitasatospora	201174|Actinobacteria	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
k59_1643590_2	391598.FBBAL38_02555	6.59e-31	120.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1417346_1	1515746.HR45_01870	1.02e-36	132.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,2Q8GF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF808)	yedI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_1360213_1	62928.azo3837	3.28e-25	102.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,2KU8K@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_1360213_2	1348657.M622_00790	6.85e-68	210.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,2KUKC@206389|Rhodocyclales	206389|Rhodocyclales	P	COG4149 ABC-type molybdate transport system, permease component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_1077760_1	572480.Arnit_1968	3.64e-164	474.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_1077763_1	1406840.Q763_00335	1.51e-48	174.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia,2P0JG@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1077763_2	1406840.Q763_00330	2.2e-58	196.0	COG0521@1|root,COG0521@2|Bacteria,4NHV5@976|Bacteroidetes,1HXT5@117743|Flavobacteriia,2NUQE@237|Flavobacterium	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_400804_1	1123517.JOMR01000001_gene1743	2.85e-211	594.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,4607R@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_400804_2	317025.Tcr_0610	7.49e-91	271.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4603D@72273|Thiotrichales	72273|Thiotrichales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_1699852_2	1397528.Q671_14265	1.12e-81	258.0	COG0582@1|root,COG0582@2|Bacteria,1N45B@1224|Proteobacteria,1RNDM@1236|Gammaproteobacteria,1XJFW@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_5106_1	1349785.BAUG01000045_gene2272	3.94e-138	392.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_5106_2	313603.FB2170_07509	1.7e-28	120.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia,2PGME@252356|Maribacter	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1417365_1	688270.Celal_0645	1.63e-19	82.8	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1I3Q8@117743|Flavobacteriia,1FAG7@104264|Cellulophaga	976|Bacteroidetes	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_457425_1	391612.CY0110_03084	1.37e-74	244.0	2B8KV@1|root,321W5@2|Bacteria,1GMTM@1117|Cyanobacteria,3KKAC@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1247357_1	996306.SSUR61_1063	2.62e-15	74.7	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1WT5B@1307|Streptococcus suis	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_513185_2	1120951.AUBG01000013_gene2569	3.36e-61	204.0	COG3177@1|root,COG3177@2|Bacteria,4NG08@976|Bacteroidetes,1I0BA@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k59_1304905_1	491915.Aflv_2238	3.32e-32	130.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,N6_Mtase,TaqI_C
k59_400817_1	323850.Shew_2665	4.58e-81	272.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria,2Q8MN@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	short-chain dehydrogenase reductase SDR	pfaA	-	-	ko:K21783	ko00333,ko01130,map00333,map01130	M00837,M00838	R11665	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k59_343693_1	572480.Arnit_1241	6.17e-255	729.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,42M05@68525|delta/epsilon subdivisions,2YNMZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_570085_1	1123514.KB905899_gene1536	9.4e-44	149.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,461A7@72273|Thiotrichales	72273|Thiotrichales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_570085_2	1123518.ARWI01000001_gene733	8.87e-56	182.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,460NI@72273|Thiotrichales	72273|Thiotrichales	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1643642_1	572480.Arnit_2909	7.21e-89	271.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2YP1Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
k59_231500_1	326298.Suden_0991	3.06e-87	276.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2YMN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA_synt_2f
k59_739568_1	62928.azo3852	1.13e-90	286.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,2KUPP@206389|Rhodocyclales	206389|Rhodocyclales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1643646_1	323850.Shew_1473	8.51e-101	298.0	COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,2Q9FK@267890|Shewanellaceae	1236|Gammaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	SO2179	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PTPS
k59_683519_1	1121912.AUHD01000008_gene172	1.47e-102	307.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1HY6H@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
k59_683519_2	985255.APHJ01000021_gene1772	9.06e-20	81.3	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia,2P71P@244698|Gillisia	976|Bacteroidetes	U	mttA/Hcf106 family	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_683519_3	1380600.AUYN01000007_gene3110	1.07e-132	382.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_5144_1	1121918.ARWE01000001_gene28	1.33e-67	208.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria,43V68@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K21902	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_175032_1	1120951.AUBG01000011_gene2377	5.07e-21	90.5	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes,1I0BS@117743|Flavobacteriia	976|Bacteroidetes	S	5'-nucleotidase, lipoprotein e(P4) family	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
k59_175032_2	525257.HMPREF0204_12071	3.2e-19	80.1	COG0640@1|root,COG0640@2|Bacteria,4NQ33@976|Bacteroidetes,1I331@117743|Flavobacteriia,3ZRXS@59732|Chryseobacterium	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_965518_1	317025.Tcr_0128	5.01e-35	132.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,45ZUX@72273|Thiotrichales	72273|Thiotrichales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_965518_2	317025.Tcr_0127	3.15e-68	206.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,460QC@72273|Thiotrichales	72273|Thiotrichales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1022286_2	392500.Swoo_0503	9.5e-59	200.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,2QARI@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DEAD DEAH box helicase domain protein	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
k59_513234_1	245174.XP_009266115.1	4.15e-12	65.1	COG0048@1|root,KOG1750@2759|Eukaryota,3A1XA@33154|Opisthokonta,3P2WN@4751|Fungi,3V16T@5204|Basidiomycota	4751|Fungi	J	Belongs to the universal ribosomal protein uS12 family	-	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_231521_1	1203606.HMPREF1526_02046	1.63e-68	224.0	COG2730@1|root,COG2730@2|Bacteria,1UFE1@1239|Firmicutes,24EUH@186801|Clostridia,36ENF@31979|Clostridiaceae	186801|Clostridia	M	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Cellulase
k59_1134822_1	1237149.C900_04536	6.61e-86	259.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_1134822_2	1237149.C900_04537	1.91e-05	46.2	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,47JQR@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_1360287_1	1121898.Q766_13995	6.15e-60	192.0	COG0494@1|root,COG4111@1|root,COG0494@2|Bacteria,COG4111@2|Bacteria,4NMPE@976|Bacteroidetes,1I0DT@117743|Flavobacteriia,2NU74@237|Flavobacterium	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_61944_1	572480.Arnit_1781	9.72e-139	414.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_1417435_1	1249480.B649_05405	1.07e-238	667.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,42YVM@68525|delta/epsilon subdivisions,2YRBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1417435_2	1131269.AQVV01000009_gene1135	1.46e-15	72.8	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
k59_1473612_1	1249480.B649_07390	6.98e-11	70.9	COG2304@1|root,COG4932@1|root,COG5295@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1QU09@1224|Proteobacteria,43DI2@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,VWA_2
k59_343763_1	1484460.JSWG01000009_gene206	1.18e-30	117.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1HYH4@117743|Flavobacteriia	976|Bacteroidetes	M	heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_343763_2	983544.Lacal_1056	1.24e-76	232.0	COG0463@1|root,COG0463@2|Bacteria,4NGJK@976|Bacteroidetes,1HXEY@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254
k59_1247432_1	1380600.AUYN01000006_gene663	5.07e-121	348.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1HYAA@117743|Flavobacteriia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_1247432_2	1122225.AULQ01000005_gene2600	1.9e-72	219.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
k59_1247432_3	1380600.AUYN01000006_gene665	8.62e-190	561.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1643708_1	1178825.ALIH01000004_gene2883	3.35e-112	338.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_457527_1	398579.Spea_2922	2.13e-135	390.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,2Q9MT@267890|Shewanellaceae	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118261_1	929558.SMGD1_1022	1.08e-25	102.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	fib	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_118261_2	929558.SMGD1_1023	2.82e-05	46.6	COG1472@1|root,COG3023@1|root,COG1472@2|Bacteria,COG3023@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2YN15@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glycosyl hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidase_2,Glyco_hydro_3
k59_1475246_1	391598.FBBAL38_02125	3.84e-130	379.0	COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,1HZ6W@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome bd ubiquinol oxidase, subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_1701571_1	869213.JCM21142_104254	1.04e-196	564.0	2CGU2@1|root,2Z7ZH@2|Bacteria,4NHFA@976|Bacteroidetes,47SVI@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_1701571_2	1121887.AUDK01000024_gene1095	1.45e-172	492.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia,2NTBI@237|Flavobacterium	976|Bacteroidetes	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
k59_289403_2	90814.KL370892_gene2074	7.17e-151	438.0	COG0420@1|root,COG0420@2|Bacteria,1QVXH@1224|Proteobacteria,1T2N6@1236|Gammaproteobacteria,4626J@72273|Thiotrichales	72273|Thiotrichales	L	3'-5' exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_1249071_1	1453498.LG45_09440	1.75e-16	84.7	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NU73@237|Flavobacterium	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
k59_910529_1	1094508.Tsac_2382	3.5e-24	114.0	COG0784@1|root,COG2199@1|root,COG3290@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,42FTQ@68295|Thermoanaerobacterales	186801|Clostridia	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,GGDEF,PAS,PAS_8,PAS_9,Response_reg
k59_685282_1	1380600.AUYN01000006_gene669	4.44e-147	422.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_853686_1	411154.GFO_2714	7.59e-86	256.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1HZGZ@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_853686_2	312309.VF_1472	5.91e-12	60.1	COG4338@1|root,COG4338@2|Bacteria,1NGIS@1224|Proteobacteria,1SGEQ@1236|Gammaproteobacteria,1XZCB@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256
k59_345355_1	1191523.MROS_1570	6.05e-74	235.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
k59_345355_2	1191523.MROS_1571	9.74e-09	56.2	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hybB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iAPECO1_1312.APECO1_3427,iE2348C_1286.E2348C_3282,iECABU_c1320.ECABU_c34010,iECOK1_1307.ECOK1_3414,iECS88_1305.ECS88_3377,iUMN146_1321.UM146_01380,iUTI89_1310.UTI89_C3417	NrfD
k59_119811_1	1380600.AUYN01000006_gene476	6.89e-92	281.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_119811_2	746697.Aeqsu_1617	1.39e-59	187.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1HWX6@117743|Flavobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_798027_1	1121931.AUHG01000016_gene1113	1.89e-18	89.7	COG0419@1|root,COG0419@2|Bacteria,4NH9H@976|Bacteroidetes,1HYCM@117743|Flavobacteriia	976|Bacteroidetes	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_1645296_1	1121931.AUHG01000017_gene1523	4.47e-111	329.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_1645296_2	1121931.AUHG01000017_gene1524	2.57e-52	174.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_402554_1	991.IW20_02410	5.1e-209	610.0	COG3866@1|root,COG3866@2|Bacteria,4NHZ1@976|Bacteroidetes,1HZ7I@117743|Flavobacteriia,2NZW9@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
k59_402554_2	1348583.ATLH01000005_gene954	5.95e-171	486.0	COG0673@1|root,COG0673@2|Bacteria,4NEQB@976|Bacteroidetes,1HZ01@117743|Flavobacteriia,1F9T8@104264|Cellulophaga	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	yvaA	-	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_402554_3	445961.IW15_14320	1.04e-09	58.2	COG2755@1|root,COG2755@2|Bacteria,4NKE5@976|Bacteroidetes,1HXIM@117743|Flavobacteriia,3ZQBS@59732|Chryseobacterium	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Pec_lyase
k59_1701625_1	563040.Saut_0766	2.54e-24	97.8	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1701625_2	929558.SMGD1_2261	1.36e-28	112.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_1039168_1	1380600.AUYN01000010_gene862	4.95e-41	148.0	COG1225@1|root,COG1225@2|Bacteria,4NH32@976|Bacteroidetes,1HWQJ@117743|Flavobacteriia	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
k59_586997_1	1178825.ALIH01000007_gene1580	1.81e-261	739.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_586997_2	1380600.AUYN01000009_gene959	1.71e-26	104.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HXMP@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1150815_1	563040.Saut_0359	1.04e-38	132.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,42ST2@68525|delta/epsilon subdivisions,2YPG7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_1150815_2	1537917.JU82_05070	8.07e-26	102.0	COG3713@1|root,COG3713@2|Bacteria,1MXXC@1224|Proteobacteria,42XV8@68525|delta/epsilon subdivisions,2YRZW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MltA-interacting MipA family protein	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	-
k59_134659_1	945713.IALB_1964	7.84e-07	51.2	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9	ko:K00033,ko:K00616,ko:K01810,ko:K08300,ko:K13810	ko00010,ko00030,ko00480,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,map00010,map00030,map00480,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230,map03018	M00001,M00004,M00006,M00007,M00114,M00394	R01528,R01827,R02739,R02740,R03321,R10221	RC00001,RC00376,RC00439,RC00539,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko04147	-	-	-	PGI,TAL_FSA
k59_134659_2	1096546.WYO_2372	1.59e-25	108.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,1JSET@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
k59_869634_2	1380600.AUYN01000012_gene2952	2.26e-77	239.0	2EIJA@1|root,33CAK@2|Bacteria	1380600.AUYN01000012_gene2952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_869634_3	742817.HMPREF9449_02735	1.59e-55	189.0	COG0463@1|root,COG0463@2|Bacteria,4NGHG@976|Bacteroidetes,2G11T@200643|Bacteroidia	976|Bacteroidetes	M	Core-2/I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
k59_869634_4	177439.DP0013	2.45e-28	119.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,42WPQ@68525|delta/epsilon subdivisions,2WRTN@28221|Deltaproteobacteria,2MP13@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_869634_5	391603.FBALC1_07328	7.38e-65	213.0	COG1216@1|root,COG1216@2|Bacteria,4P2W1@976|Bacteroidetes,1I8S4@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1605261_1	1168067.JAGP01000001_gene1257	1.26e-67	224.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,45ZN8@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_1264744_2	504487.JCM19302_3581	6.44e-43	147.0	COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,1I3ED@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
k59_755901_1	1121033.AUCF01000039_gene439	3.56e-33	122.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,2JRVY@204441|Rhodospirillales	204441|Rhodospirillales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_755901_2	93220.LV28_13540	3.35e-21	91.3	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,1K68I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c	soxX	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
k59_1150837_1	572480.Arnit_0649	1.94e-104	315.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2YMGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_1039203_2	563040.Saut_0856	6.65e-23	89.0	COG1722@1|root,COG1722@2|Bacteria,1Q35M@1224|Proteobacteria,42WTB@68525|delta/epsilon subdivisions,2YQRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k59_1039203_3	1172190.M947_05220	9.36e-116	337.0	COG0388@1|root,COG0388@2|Bacteria,1QBMA@1224|Proteobacteria,42PD8@68525|delta/epsilon subdivisions,2YMD1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_755916_1	1177928.TH2_08086	2.95e-113	338.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria,2JTRQ@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_978407_1	1122225.AULQ01000001_gene1444	1.67e-213	598.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
k59_978407_2	1137281.D778_00359	7.44e-153	445.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1HXCS@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_79570_1	944547.ABLL_1988	1.94e-70	226.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AKC@68525|delta/epsilon subdivisions,2YRPM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_1546520_1	929558.SMGD1_2847	8.04e-137	397.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2YMX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1264788_1	1137281.D778_01598	9.58e-72	222.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia	976|Bacteroidetes	S	amidophosphoribosyl-transferase	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
k59_1150874_1	411154.GFO_3280	1.88e-125	363.0	28JCX@1|root,2Z97G@2|Bacteria,4NII8@976|Bacteroidetes,1I0YE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_21340_1	1537994.JQFW01000042_gene2259	2.27e-15	76.3	COG0793@1|root,COG0793@2|Bacteria,1R88M@1224|Proteobacteria,1RY1G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_1717401_1	929558.SMGD1_0539	4.16e-127	371.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1202610_1	572480.Arnit_1203	1.54e-96	286.0	COG0745@1|root,COG0745@2|Bacteria,1Q49B@1224|Proteobacteria,431SE@68525|delta/epsilon subdivisions,2YSE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1491587_1	1123518.ARWI01000001_gene2239	1.74e-132	384.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1491587_2	1123514.KB905899_gene652	1.59e-153	436.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,45ZWI@72273|Thiotrichales	72273|Thiotrichales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_1491587_3	1123514.KB905899_gene653	1.16e-182	510.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4600U@72273|Thiotrichales	72273|Thiotrichales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_1491587_4	90814.KL370891_gene1422	3.73e-21	94.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,45ZUD@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the folylpolyglutamate synthase family	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1717411_1	929558.SMGD1_2208	2.03e-105	317.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_869698_1	1121931.AUHG01000019_gene2970	1.15e-93	282.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_869698_2	1121931.AUHG01000019_gene2971	8.67e-25	101.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_418076_1	411154.GFO_0810	2.81e-139	406.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_1605332_1	1123518.ARWI01000001_gene1342	7.86e-18	85.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461Z4@72273|Thiotrichales	72273|Thiotrichales	NT	helical bimodular (HBM) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
k59_1605332_2	1123514.KB905899_gene888	5.43e-131	382.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,460RP@72273|Thiotrichales	72273|Thiotrichales	EGP	Drug resistance transporter Bcr CflA subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_1717418_1	411154.GFO_2861	1.71e-196	553.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan synthetase	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_701741_2	944547.ABLL_0410	9.07e-126	359.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2YMW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_1264826_1	1123518.ARWI01000001_gene464	1.67e-117	340.0	COG0600@1|root,COG0600@2|Bacteria,1PH2A@1224|Proteobacteria,1RXAN@1236|Gammaproteobacteria,462WV@72273|Thiotrichales	72273|Thiotrichales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k59_1264826_2	1123518.ARWI01000001_gene465	1.94e-67	211.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1T1X0@1236|Gammaproteobacteria,463N6@72273|Thiotrichales	72273|Thiotrichales	P	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_475087_1	1306406.ASHX01000001_gene2419	2.09e-05	51.6	COG5479@1|root,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
k59_1377080_1	234267.Acid_7204	7.81e-34	129.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria	57723|Acidobacteria	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_926930_1	196367.JNFG01000059_gene452	8.68e-05	47.8	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KG4B@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_926930_2	247639.MGP2080_00345	7.01e-59	210.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria	1224|Proteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
k59_1324466_1	1250006.JHZZ01000001_gene3346	2.04e-60	206.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1I0F2@117743|Flavobacteriia,3VXGE@52959|Polaribacter	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_1324466_2	1336803.PHEL49_2081	2.48e-200	569.0	COG5492@1|root,COG5492@2|Bacteria,4PM9P@976|Bacteroidetes,1I0RN@117743|Flavobacteriia,3VX02@52959|Polaribacter	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
k59_588566_1	945713.IALB_0644	1.38e-16	78.2	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_588566_2	234621.RER_26430	1.3e-27	102.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4G24W@85025|Nocardiaceae	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_250817_1	1123514.KB905899_gene925	3.64e-65	221.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,45ZMI@72273|Thiotrichales	72273|Thiotrichales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_136238_1	391603.FBALC1_10377	6.38e-17	79.7	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136238_2	1380600.AUYN01000001_gene2779	2.58e-234	654.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1662490_1	1288826.MSNKSG1_17885	9.65e-59	186.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,464TW@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_1662490_2	1453501.JELR01000005_gene1743	7.72e-80	238.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,466ID@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1662490_3	314285.KT71_00995	1.8e-57	180.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1JA3T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_136239_1	1158182.KB905020_gene2297	6.43e-27	118.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,1T4M3@1236|Gammaproteobacteria,1WY59@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_1548028_1	1178825.ALIH01000009_gene1357	7.89e-14	77.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1606941_2	944547.ABLL_0618	5.64e-73	223.0	COG1040@1|root,COG1040@2|Bacteria,1Q1C2@1224|Proteobacteria,42T93@68525|delta/epsilon subdivisions,2YPEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	transformation system protein	ctsW	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k59_1266261_2	326298.Suden_1929	3.76e-55	179.0	COG0790@1|root,COG0790@2|Bacteria,1NY7Z@1224|Proteobacteria,42T5I@68525|delta/epsilon subdivisions,2YPQ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_703453_1	392500.Swoo_1203	2.75e-67	204.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,2QBXV@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Required for insertion of 4Fe-4S clusters for at least IspG	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k59_703453_2	1565129.JSFF01000020_gene1575	4.98e-40	136.0	2AFJ7@1|root,315K0@2|Bacteria,1QDF3@1224|Proteobacteria,1T9DP@1236|Gammaproteobacteria,2QC31@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_871177_1	1249975.JQLP01000005_gene2637	2.05e-36	124.0	2CKK3@1|root,30X4A@2|Bacteria,4PAG0@976|Bacteroidetes,1IEC1@117743|Flavobacteriia,2P728@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_871177_2	411154.GFO_3091	3.8e-85	268.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_645700_1	572480.Arnit_0669	8.13e-89	281.0	COG2199@1|root,COG2202@1|root,COG4564@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4564@2|Bacteria,1QYD2@1224|Proteobacteria,42PVI@68525|delta/epsilon subdivisions,2YNV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9,dCache_2
k59_871186_1	1408473.JHXO01000001_gene2155	1.13e-93	299.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1493167_1	78398.KS43_04210	9.64e-50	167.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,1MQ47@122277|Pectobacterium	1236|Gammaproteobacteria	J	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_1493167_2	626887.J057_07426	6.64e-23	91.3	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,4678H@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	COG1186 Protein chain release factor B	yaeJ	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_194160_1	1121904.ARBP01000006_gene4087	5.69e-39	148.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_194160_2	1158294.JOMI01000003_gene2449	2.88e-06	47.4	COG0454@1|root,COG0456@2|Bacteria,4PK5U@976|Bacteroidetes,2FXT3@200643|Bacteroidia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_1203664_1	90814.KL370891_gene710	7.21e-134	384.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,46081@72273|Thiotrichales	72273|Thiotrichales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_1324548_1	1380358.JADJ01000015_gene2334	8.93e-15	71.2	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1XKGN@135619|Oceanospirillales	135619|Oceanospirillales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_250895_1	543913.D521_0629	1.85e-73	231.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,2VQN6@28216|Betaproteobacteria,1KQV8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_1435385_1	80637.XP_007768591.1	1.16e-09	64.3	COG0578@1|root,KOG0042@2759|Eukaryota,38FKM@33154|Opisthokonta,3NU42@4751|Fungi,3UZ87@5204|Basidiomycota,227WK@155619|Agaricomycetes	4751|Fungi	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	GUT2	GO:0001302,GO:0003674,GO:0003824,GO:0004368,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005975,GO:0006066,GO:0006071,GO:0006072,GO:0006116,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009117,GO:0009331,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016901,GO:0019362,GO:0019400,GO:0019637,GO:0019674,GO:0019751,GO:0019867,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032502,GO:0032592,GO:0032991,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0046483,GO:0046496,GO:0048869,GO:0051186,GO:0052646,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0098573,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901564,GO:1901615,GO:1902494,GO:1990204	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	iMM904.YIL155C,iND750.YIL155C	DAO,DAO_C,EF-hand_7
k59_757566_1	745718.JADT01000001_gene1621	3.2e-153	432.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1HY9V@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_136302_1	1137281.D778_00444	1.03e-124	367.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_136302_2	1122225.AULQ01000009_gene317	9.07e-15	67.4	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,1I55S@117743|Flavobacteriia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_645743_1	1123514.KB905899_gene1504	2.08e-92	280.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,461U7@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k59_306743_1	411154.GFO_1018	6.8e-151	429.0	COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1HXK4@117743|Flavobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor RskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
k59_376368_1	504487.JCM19302_543	5.43e-49	159.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1HXVM@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_376368_2	1380600.AUYN01000009_gene1212	5.3e-221	612.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1HX7F@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_376368_3	1178825.ALIH01000007_gene1706	2.15e-218	626.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1HXB5@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
k59_264963_1	1353528.DT23_09435	3.16e-152	453.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2XNIN@285107|Thioclava	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_1508300_1	572480.Arnit_2519	6.57e-101	323.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1167670_1	1250006.JHZZ01000001_gene2221	2.69e-73	234.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1IC3K@117743|Flavobacteriia,3VXCE@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1167670_2	1250006.JHZZ01000001_gene2242	9.37e-92	285.0	COG5434@1|root,COG5434@2|Bacteria,4NTBW@976|Bacteroidetes	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_150952_1	411154.GFO_2146	2.43e-63	204.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1HWZC@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k59_1110848_1	326298.Suden_1902	9.57e-106	324.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1393259_1	944547.ABLL_2825	2.71e-92	282.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,42MA8@68525|delta/epsilon subdivisions,2YNA8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_95761_1	1297742.A176_06897	5.4e-55	186.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria,2YTWM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_939866_1	563040.Saut_0640	9.89e-44	146.0	COG0454@1|root,COG0456@2|Bacteria,1N41Y@1224|Proteobacteria,42UGC@68525|delta/epsilon subdivisions,2YQ4N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_939866_2	1537917.JU82_05635	1.16e-42	149.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_939867_1	929558.SMGD1_1586	3.2e-58	186.0	COG0745@1|root,COG0745@2|Bacteria,1QZNH@1224|Proteobacteria,42SJZ@68525|delta/epsilon subdivisions,2YPIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_601755_1	425104.Ssed_4156	2.78e-22	94.7	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,2QA7F@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM sodium neurotransmitter symporter	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_1790631_1	318167.Sfri_0452	4.74e-106	333.0	COG0210@1|root,COG0551@1|root,COG0210@2|Bacteria,COG0551@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,2QA64@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DNA topoisomerase, type IA, zn finger domain protein	helD	-	3.6.4.12	ko:K03658	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_IV_N,UvrD-helicase,UvrD_C,zf-C4_Topoisom
k59_1167702_1	411154.GFO_2143	8.96e-118	360.0	COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,1HZVW@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
k59_1449727_1	1250005.PHEL85_2140	7.2e-312	862.0	COG1290@1|root,COG1290@2|Bacteria,4NI64@976|Bacteroidetes,1I0MA@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1339708_2	458817.Shal_3382	4.32e-21	93.2	COG0484@1|root,COG0484@2|Bacteria,1N89W@1224|Proteobacteria,1SDS5@1236|Gammaproteobacteria,2QDDR@267890|Shewanellaceae	1236|Gammaproteobacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_939893_1	1121912.AUHD01000007_gene516	4.05e-81	266.0	COG0366@1|root,COG0366@2|Bacteria,4PMNI@976|Bacteroidetes,1IJVU@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_1167734_2	985255.APHJ01000040_gene323	8.58e-52	163.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1I2TE@117743|Flavobacteriia,2P6Y0@244698|Gillisia	976|Bacteroidetes	J	Ribosomal protein S17	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_376459_1	926559.JoomaDRAFT_1804	9.57e-52	182.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_376459_2	926559.JoomaDRAFT_1805	4.63e-91	283.0	COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,1HZJZ@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_37026_2	497321.C664_02715	9.66e-79	244.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,2KUWH@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1110937_1	62928.azo3782	1.73e-113	342.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,2KUBD@206389|Rhodocyclales	206389|Rhodocyclales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_37052_1	497321.C664_01555	5.68e-78	250.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,2KUJR@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1733517_1	1406840.Q763_09600	4.93e-134	384.0	COG0358@1|root,COG0358@2|Bacteria,4NH5X@976|Bacteroidetes,1I03T@117743|Flavobacteriia,2NVRI@237|Flavobacterium	976|Bacteroidetes	L	DNA primase	traP	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,zf-CHC2
k59_601824_1	1380600.AUYN01000007_gene3083	4.18e-31	121.0	COG1541@1|root,COG1541@2|Bacteria,4NFFT@976|Bacteroidetes,1HZKR@117743|Flavobacteriia	976|Bacteroidetes	H	COG1541 Coenzyme F390 synthetase	capK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_601824_2	1178825.ALIH01000009_gene1324	6.85e-84	259.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_1562680_1	90814.KL370891_gene1592	2.05e-32	127.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_1562680_2	1123514.KB905902_gene289	1.63e-113	330.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,1S40I@1236|Gammaproteobacteria,46161@72273|Thiotrichales	72273|Thiotrichales	O	2OG-Fe(II) oxygenase	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
k59_1790724_1	929558.SMGD1_1558	7.88e-90	270.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2YMYB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_1790724_2	563040.Saut_1915	1.97e-42	144.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2YMQX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1621641_1	1123518.ARWI01000001_gene1568	6.86e-76	237.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,4605D@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
k59_153115_1	637905.SVI_4239	2.68e-50	164.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,2QA9D@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_153115_2	323850.Shew_0098	7.8e-67	214.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria,2Q8ST@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase, HAMP region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1792808_1	563040.Saut_1862	2.12e-121	352.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2YMGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1792808_2	929558.SMGD1_1596	5.51e-54	176.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2YT08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_1735552_1	411154.GFO_1558	7.31e-87	258.0	2C0UP@1|root,31BZQ@2|Bacteria,4NQIC@976|Bacteroidetes,1I38V@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
k59_1735552_2	411154.GFO_1557	2.34e-66	209.0	COG3121@1|root,COG3121@2|Bacteria,4NK7D@976|Bacteroidetes,1I142@117743|Flavobacteriia	976|Bacteroidetes	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	PapD_N
k59_721519_1	1121931.AUHG01000012_gene2690	4.74e-142	431.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_887975_1	326298.Suden_1802	8.99e-126	361.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_1623309_1	1070319.CAGGBEG34_690003	4.86e-88	268.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,1K0P8@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	pmrIb	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1169849_1	236097.ADG881_65	0.000254	43.5	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T2C6@1236|Gammaproteobacteria,1XR3Q@135619|Oceanospirillales	135619|Oceanospirillales	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1169849_3	990073.ATHU01000001_gene179	1.51e-62	199.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2YNWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1735562_1	1121931.AUHG01000011_gene2232	4.01e-23	95.9	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HXME@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_1735562_2	865937.Gilli_0631	2.22e-30	117.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia,2P5EP@244698|Gillisia	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
k59_1395478_1	1317122.ATO12_00580	2.65e-93	280.0	COG3774@1|root,COG3774@2|Bacteria,4NITG@976|Bacteroidetes,1I139@117743|Flavobacteriia,2YGPI@290174|Aquimarina	976|Bacteroidetes	M	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
k59_547564_1	563040.Saut_1026	1.64e-51	176.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
k59_774157_1	572480.Arnit_0800	6.5e-146	429.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_97991_1	1123517.JOMR01000001_gene1910	5.94e-30	116.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4605T@72273|Thiotrichales	72273|Thiotrichales	O	molecular chaperone	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_97991_2	1123514.KB905900_gene2084	6.37e-09	55.8	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,461Y3@72273|Thiotrichales	72273|Thiotrichales	H	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_888027_1	1178825.ALIH01000001_gene2599	6.12e-32	112.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,1I53X@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_888027_4	1178825.ALIH01000001_gene2602	2.35e-44	145.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1I2VR@117743|Flavobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_547600_1	1123514.KB905899_gene1519	2.25e-30	117.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,45ZZA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_547600_2	1123518.ARWI01000001_gene713	2.51e-182	518.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,45ZX7@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_995904_1	392499.Swit_5197	4.34e-07	50.8	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,2K3NU@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein involved in DNA binding and transposition, DNA-mediated	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1283165_1	62928.azo3788	1.67e-124	358.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,2VI8M@28216|Betaproteobacteria,2KV5F@206389|Rhodocyclales	206389|Rhodocyclales	C	Prokaryotic cytochrome b561	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_547604_1	1121931.AUHG01000019_gene3032	2.73e-147	425.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_1113092_1	1236541.BALL01000011_gene1829	1.18e-111	331.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,2Q9U1@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM CBS domain containing protein	yfjD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_493037_1	1123518.ARWI01000001_gene1950	2.09e-15	74.3	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,460EG@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_493037_2	1123518.ARWI01000001_gene1949	2.67e-72	232.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,45ZSQ@72273|Thiotrichales	72273|Thiotrichales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_98036_1	1121931.AUHG01000019_gene2973	1.19e-109	329.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
k59_1395531_1	411154.GFO_3031	8.94e-43	143.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1I17F@117743|Flavobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1395531_2	1121931.AUHG01000010_gene26	7.03e-19	85.1	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1I17W@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_1113106_1	1137281.D778_01957	3.12e-101	306.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1215303_1	411154.GFO_0782	3.49e-73	231.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_210976_1	1442598.JABW01000030_gene1384	2.6e-92	286.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	-	-	-	ko:K02282,ko:K04562	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ,CbiA,GNVR,ParA,Wzz
k59_888090_1	1353528.DT23_14295	3.31e-74	234.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2XKYX@285107|Thioclava	28211|Alphaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_153259_2	945713.IALB_1623	5.82e-114	327.0	COG0377@1|root,COG0377@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_436559_2	90814.KL370891_gene1210	5.82e-81	247.0	2A9HH@1|root,30YPR@2|Bacteria,1RFHF@1224|Proteobacteria,1S4ZX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_436559_3	1123514.KB905899_gene1177	1.05e-07	55.1	COG3528@1|root,COG3528@2|Bacteria,1QSPH@1224|Proteobacteria,1RNRA@1236|Gammaproteobacteria,463R7@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
k59_1169983_2	1123517.JOMR01000001_gene1476	1.83e-12	66.6	COG3018@1|root,COG3018@2|Bacteria,1N8R1@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k59_603630_1	439235.Dalk_1601	3.27e-47	155.0	COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,PAS_8,Response_reg
k59_603630_2	1089550.ATTH01000001_gene1989	7.63e-10	60.8	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1FJV8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
k59_662949_2	1237149.C900_03157	3.18e-84	256.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47PF1@768503|Cytophagia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_995996_1	90814.KL370891_gene1265	7.54e-124	364.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,45ZSM@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1452084_1	944547.ABLL_2639	5.85e-173	496.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_1186537_2	983544.Lacal_2753	1.27e-73	226.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1HYRJ@117743|Flavobacteriia	976|Bacteroidetes	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
k59_734638_1	1144275.COCOR_03222	8.39e-22	95.9	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_1751421_1	90814.KL370891_gene1480	2.56e-184	522.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,1RQCD@1236|Gammaproteobacteria,4626A@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I
k59_1751421_2	317025.Tcr_1671	8.55e-28	106.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,460ME@72273|Thiotrichales	72273|Thiotrichales	O	O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1073539_1	1278309.KB907108_gene1610	2e-62	199.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1XHYQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
k59_1073539_2	1166130.H650_07540	3.17e-05	46.6	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,3X0M5@547|Enterobacter	1236|Gammaproteobacteria	S	membrane transporter protein	yfcA	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K07090,ko:K11312	-	-	-	-	ko00000	-	-	-	TauE
k59_1017127_1	929558.SMGD1_1598	1.59e-31	121.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2YTJQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_1017127_2	929558.SMGD1_1597	1.51e-72	229.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2YRI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_1468886_1	1303518.CCALI_01148	0.000654	42.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_1468886_2	316056.RPC_4507	1.57e-83	248.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2UDW5@28211|Alphaproteobacteria,3K4D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_678220_1	1123514.KB905899_gene1564	6.3e-134	393.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,460G5@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
k59_678220_2	317025.Tcr_0543	7.43e-61	202.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,45ZYZ@72273|Thiotrichales	72273|Thiotrichales	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_565234_1	398579.Spea_3667	1.63e-98	316.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,2Q95R@267890|Shewanellaceae	1236|Gammaproteobacteria	EKT	PFAM histidine kinase, HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,SBP_bac_3,dCache_1
k59_226350_1	1121875.KB907549_gene1898	3.7e-77	258.0	COG1983@1|root,COG5373@1|root,COG1983@2|Bacteria,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1HZB4@117743|Flavobacteriia	976|Bacteroidetes	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k59_1074024_1	984262.SGRA_2011	1.23e-36	134.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-superfamily hydrolase subfamily IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1074024_2	1035193.HMPREF9073_03223	4.24e-230	643.0	COG2271@1|root,COG2271@2|Bacteria,4NGX4@976|Bacteroidetes,1I4JV@117743|Flavobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	glpT	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
k59_1074024_3	926559.JoomaDRAFT_3136	2.41e-132	395.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,1IIHF@117743|Flavobacteriia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	glpQ1_5	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
k59_1074024_4	1449076.JOOE01000003_gene3285	2.34e-92	317.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TS2K@28211|Alphaproteobacteria,2KD9D@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_678977_1	1537917.JU82_03225	1.45e-10	60.8	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_678977_2	929558.SMGD1_0605	8.1e-77	238.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,42M00@68525|delta/epsilon subdivisions,2YMF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1130889_1	305700.B447_05970	4.04e-136	390.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,2VJP1@28216|Betaproteobacteria,2KVVH@206389|Rhodocyclales	206389|Rhodocyclales	S	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_1130889_2	497321.C664_13939	7.9e-60	195.0	COG2391@1|root,COG2391@2|Bacteria,1MWWP@1224|Proteobacteria,2VNR8@28216|Betaproteobacteria,2KUHZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k59_1582685_1	1123518.ARWI01000001_gene1951	4.04e-225	646.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,45ZYC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_283418_1	1178825.ALIH01000003_gene2132	7.81e-60	192.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_283418_2	1380600.AUYN01000007_gene3279	4.42e-176	496.0	28H5K@1|root,2Z7I6@2|Bacteria,4NFX9@976|Bacteroidetes,1HXUE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_283418_3	1122179.KB890458_gene680	1.21e-125	367.0	COG2084@1|root,COG2084@2|Bacteria,4NKRT@976|Bacteroidetes,1J0CJ@117747|Sphingobacteriia	976|Bacteroidetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_283418_4	504487.JCM19302_3931	3.3e-75	228.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_170605_1	317025.Tcr_0922	3.16e-305	840.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,4600J@72273|Thiotrichales	72273|Thiotrichales	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_1639249_1	1232410.KI421422_gene2032	6.27e-127	383.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_396560_1	1172190.M947_00795	2.41e-200	585.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_904939_1	411154.GFO_3489	7.78e-31	117.0	COG2141@1|root,COG2141@2|Bacteria,4NDW2@976|Bacteroidetes,1HXDE@117743|Flavobacteriia	976|Bacteroidetes	C	luciferase family oxidoreductase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_904939_2	1121931.AUHG01000010_gene705	3.17e-101	308.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,1HZX1@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_1200_1	1237149.C900_00766	1.03e-56	196.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
k59_1469454_2	1178825.ALIH01000007_gene1751	2.3e-15	84.3	2E3AK@1|root,32YA3@2|Bacteria,4PQ2A@976|Bacteroidetes,1IKYT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57673_1	1121931.AUHG01000010_gene799	6.71e-116	345.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1HZVU@117743|Flavobacteriia	976|Bacteroidetes	IQ	amp-binding	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1413319_1	1178825.ALIH01000008_gene766	2.3e-85	287.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HYR,Laminin_G_3,SprB
k59_1243519_2	90814.KL370892_gene2314	1.82e-119	368.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535,ko:K12955	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.24,3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_396561_2	1173024.KI912152_gene349	1.42e-23	100.0	COG4185@1|root,COG4185@2|Bacteria,1G56J@1117|Cyanobacteria	1117|Cyanobacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
k59_396561_3	1123392.AQWL01000008_gene1274	3.13e-18	80.1	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria	28216|Betaproteobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	SNase
k59_57678_1	90814.KL370891_gene602	5.95e-81	246.0	2CMG5@1|root,32SEP@2|Bacteria,1N1C2@1224|Proteobacteria,1SE5Q@1236|Gammaproteobacteria,4629F@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114152_1	28229.ND2E_1975	4.93e-38	135.0	COG4758@1|root,COG4758@2|Bacteria,1RANH@1224|Proteobacteria,1RSEZ@1236|Gammaproteobacteria,2Q725@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
k59_848050_1	1121898.Q766_02695	2.83e-23	97.8	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia,2NS9I@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
k59_848050_2	1046627.BZARG_1432	1.1e-157	451.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,1I0ZQ@117743|Flavobacteriia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
k59_848050_3	1137281.D778_00409	9.25e-31	113.0	2CBAI@1|root,32REB@2|Bacteria,4NF3F@976|Bacteroidetes,1I330@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_565953_1	1123517.JOMR01000001_gene615	2.09e-63	206.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,45ZXR@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_565953_2	563040.Saut_0926	1.7e-23	102.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_791887_1	1121931.AUHG01000011_gene2430	3.38e-68	233.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_1582721_1	563040.Saut_0438	7.81e-86	268.0	COG1538@1|root,COG1538@2|Bacteria,1NSNH@1224|Proteobacteria,42QPF@68525|delta/epsilon subdivisions,2YNZ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_904961_1	396588.Tgr7_0340	2.83e-141	426.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1WWPF@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1130938_1	1123228.AUIH01000013_gene174	8.97e-72	241.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1XIUJ@135619|Oceanospirillales	135619|Oceanospirillales	L	Putative exonuclease SbcCD, C subunit	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_565963_1	983544.Lacal_1595	2.95e-94	302.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_565963_2	1178825.ALIH01000011_gene77	7.88e-81	251.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_1130939_1	1123228.AUIH01000004_gene1110	5.42e-57	189.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1XJKH@135619|Oceanospirillales	135619|Oceanospirillales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1413351_1	929558.SMGD1_2247	1.58e-99	296.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2YMJ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KO	Hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_170645_1	317025.Tcr_1924	4.38e-55	200.0	COG0642@1|root,COG2972@1|root,COG3437@1|root,COG3829@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1T3XA@1236|Gammaproteobacteria,461JT@72273|Thiotrichales	72273|Thiotrichales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_961346_1	1123518.ARWI01000001_gene683	5.66e-27	105.0	COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,1S88Y@1236|Gammaproteobacteria,462IW@72273|Thiotrichales	72273|Thiotrichales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_961346_2	1123518.ARWI01000001_gene683	3.86e-61	196.0	COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,1S88Y@1236|Gammaproteobacteria,462IW@72273|Thiotrichales	72273|Thiotrichales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_227149_1	563040.Saut_0581	1.53e-113	345.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_396612_1	1178825.ALIH01000015_gene1892	2.49e-32	119.0	COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1HWKN@117743|Flavobacteriia	976|Bacteroidetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_396612_2	1380600.AUYN01000001_gene2318	2.09e-132	404.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_1582765_1	563040.Saut_0241	2.23e-114	339.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2YNT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1469511_1	1123518.ARWI01000001_gene2109	2.64e-141	410.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,45ZMX@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_114218_1	983544.Lacal_0973	1.35e-41	144.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_114218_2	755732.Fluta_3735	5.43e-148	429.0	COG3386@1|root,COG3386@2|Bacteria,4PKGZ@976|Bacteroidetes,1IJ8R@117743|Flavobacteriia,2PARQ@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114218_3	1123234.AUKI01000017_gene2519	4.2e-52	178.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1526227_1	90814.KL370891_gene1745	1.83e-131	400.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,45ZVX@72273|Thiotrichales	72273|Thiotrichales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_57754_1	983544.Lacal_0517	2.21e-114	336.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_1582785_1	929558.SMGD1_0396	2.76e-154	452.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_227201_1	504487.JCM19302_3282	4.34e-128	379.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_114241_1	1123514.KB905899_gene1679	6.31e-19	85.1	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,45ZQY@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_114241_2	90814.KL370891_gene390	2.8e-64	216.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,46054@72273|Thiotrichales	72273|Thiotrichales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_227202_1	1121931.AUHG01000011_gene2388	1.04e-83	276.0	COG1352@1|root,COG2201@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HWYQ@117743|Flavobacteriia	976|Bacteroidetes	T	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
k59_1695771_2	215803.DB30_4078	2.89e-13	72.0	COG0625@1|root,COG0625@2|Bacteria,1MX33@1224|Proteobacteria,439KN@68525|delta/epsilon subdivisions,2X4XG@28221|Deltaproteobacteria,2YZSS@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_6,GST_N_4
k59_679121_1	1380600.AUYN01000001_gene2701	3.24e-28	102.0	2EA78@1|root,334BX@2|Bacteria,4NVC4@976|Bacteroidetes,1I51G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1187466_1	317025.Tcr_1549	5.14e-24	99.8	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461JQ@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_1187466_2	247634.GPB2148_2157	1.68e-24	103.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,1RZJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
k59_339925_2	1070319.CAGGBEG34_240048	1.57e-18	84.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1K06W@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_735562_1	572480.Arnit_2294	1.25e-94	287.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_735562_2	572480.Arnit_2293	3.59e-20	87.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_791986_1	1123518.ARWI01000001_gene831	1.03e-63	215.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
k59_396692_1	1415778.JQMM01000001_gene1304	8.47e-06	47.8	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,1J68D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_396692_2	572480.Arnit_0604	3.2e-61	199.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_1356664_1	1121931.AUHG01000012_gene2874	1.55e-40	150.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_1356664_2	1121931.AUHG01000012_gene2875	4.5e-44	159.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_791994_1	317025.Tcr_1003	1.93e-142	417.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,45ZSE@72273|Thiotrichales	72273|Thiotrichales	C	dihydrolipoamide dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_283583_1	572480.Arnit_0830	6.74e-107	320.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2YN35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_1353_1	1484460.JSWG01000011_gene1713	4.71e-77	253.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
k59_521650_1	1172190.M947_01590	0.000617	46.6	COG3206@1|root,COG3206@2|Bacteria,1Q68V@1224|Proteobacteria,432MZ@68525|delta/epsilon subdivisions,2YSUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1087147_1	504487.JCM19302_2468	1.3e-143	414.0	COG2755@1|root,COG2755@2|Bacteria,4NI37@976|Bacteroidetes,1HXM7@117743|Flavobacteriia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1087147_2	1380600.AUYN01000001_gene2302	1.01e-100	304.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_1031708_1	292.DM42_1866	9.68e-103	313.0	COG5484@1|root,COG5484@2|Bacteria,1QTWB@1224|Proteobacteria,2WGG0@28216|Betaproteobacteria,1KIDR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_5,Terminase_6,Terminase_6C
k59_71902_1	572480.Arnit_1675	3.68e-105	306.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2YPI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_297482_1	1121931.AUHG01000018_gene1325	3.51e-124	364.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
k59_1257166_1	637905.SVI_0230	1.29e-102	308.0	COG0477@1|root,COG0477@2|Bacteria,1QU36@1224|Proteobacteria,1T24P@1236|Gammaproteobacteria,2Q8R4@267890|Shewanellaceae	1236|Gammaproteobacteria	EGP	TIGRFAM drug resistance transporter, Bcr CflA subfamily	sflR	-	-	ko:K07552,ko:K18552	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.2,2.A.1.2.3	-	-	MFS_1
k59_1483777_1	411154.GFO_2728	2.28e-77	239.0	28Z2A@1|root,2ZKUT@2|Bacteria,4NSQ0@976|Bacteroidetes,1I0GS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1766541_1	1355368.JART01000025_gene59	6.4e-82	254.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2YMEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
k59_1597256_1	1121931.AUHG01000020_gene3172	1.47e-154	445.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_580056_1	1236494.BAJN01000003_gene659	5.86e-27	107.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,2FNE2@200643|Bacteroidia	976|Bacteroidetes	J	RNA methyltransferase TrmH	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_580056_2	1506583.JQJY01000002_gene1427	0.000186	44.3	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia,2NSB1@237|Flavobacterium	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_1653384_1	755732.Fluta_2490	7.12e-95	287.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia,2PADF@246874|Cryomorphaceae	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_693749_2	172045.KS04_07105	3.19e-73	225.0	COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,1I0PT@117743|Flavobacteriia,34PRU@308865|Elizabethkingia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_1483806_1	1565129.JSFF01000009_gene1845	1.38e-95	284.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,2QA5F@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Methylates ribosomal protein L11	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_353228_1	1121931.AUHG01000011_gene2430	3.42e-94	305.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_353230_1	1123514.KB905899_gene1921	3.77e-52	176.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,460GP@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_353230_2	1123514.KB905899_gene1922	6.59e-58	188.0	2B4HV@1|root,31X9R@2|Bacteria,1QCXM@1224|Proteobacteria,1SGTP@1236|Gammaproteobacteria,461C2@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_353230_3	317025.Tcr_0189	4.08e-18	84.3	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,4604X@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_1315036_1	1537915.JU57_06740	9.98e-54	178.0	COG0535@1|root,COG0535@2|Bacteria,1Q4MU@1224|Proteobacteria,42U7S@68525|delta/epsilon subdivisions,2YRZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_1653407_1	1355374.JARU01000001_gene418	4.16e-21	92.4	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1653407_2	367737.Abu_0385	1.02e-14	70.5	2AIYH@1|root,31ARU@2|Bacteria,1Q60N@1224|Proteobacteria,42WN0@68525|delta/epsilon subdivisions,2YQ8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF2018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2018
k59_14250_1	1123518.ARWI01000001_gene839	5.59e-08	53.9	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,460AF@72273|Thiotrichales	72273|Thiotrichales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_14250_2	1123514.KB905899_gene1650	5.07e-63	196.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,460Y6@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III, chi subunit	-	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
k59_1539320_1	1168067.JAGP01000001_gene569	2.44e-37	135.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,HATPase_c,PAS_3,PAS_4,PAS_9,TPR_12,dCache_1
k59_636747_1	572480.Arnit_2658	6.13e-123	363.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2YNNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
k59_410499_1	497321.C664_04212	7.21e-84	271.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	mcrA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_918306_1	1235803.C825_01882	4.92e-36	137.0	COG5434@1|root,COG5434@2|Bacteria,4NIEA@976|Bacteroidetes,2FMVC@200643|Bacteroidia	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_1709924_1	1123518.ARWI01000001_gene1868	1.77e-61	197.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_1087219_1	504487.JCM19302_1048	6.8e-65	207.0	COG2885@1|root,COG2885@2|Bacteria,4NRJ9@976|Bacteroidetes,1I3DV@117743|Flavobacteriia	976|Bacteroidetes	M	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_1087219_2	1380600.AUYN01000009_gene1601	1.84e-72	226.0	COG3714@1|root,COG3714@2|Bacteria	2|Bacteria	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
k59_1087219_3	1197477.IA57_00990	1.73e-157	456.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1HWV6@117743|Flavobacteriia	976|Bacteroidetes	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1087222_1	1123072.AUDH01000001_gene2734	4.17e-63	207.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,2JPNJ@204441|Rhodospirillales	204441|Rhodospirillales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_1709946_1	572480.Arnit_1920	1.58e-106	317.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_1709946_2	572480.Arnit_1921	1.54e-73	239.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1766616_1	1189619.pgond44_05255	2.03e-68	218.0	2CIFM@1|root,30BMR@2|Bacteria,4NP6Z@976|Bacteroidetes,1I2BW@117743|Flavobacteriia,4C43K@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1766616_2	504487.JCM19302_2219	6.45e-174	510.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_10,TPR_12,TPR_7,TPR_8,Y_Y_Y
k59_1426790_1	1121405.dsmv_0716	1.24e-12	72.8	2EI5Z@1|root,33BXC@2|Bacteria,1NN59@1224|Proteobacteria,431F7@68525|delta/epsilon subdivisions,2WWRF@28221|Deltaproteobacteria	1224|Proteobacteria	G	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4,Polysacc_lyase
k59_297587_1	1166130.H650_02475	4.28e-33	125.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,3X1K0@547|Enterobacter	1236|Gammaproteobacteria	C	oxidase, subunit	cioA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_1653464_1	985255.APHJ01000028_gene979	4.24e-125	369.0	COG3307@1|root,COG3307@2|Bacteria,4NGIS@976|Bacteroidetes,1HYGB@117743|Flavobacteriia,2P67F@244698|Gillisia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_523244_1	1123514.KB905899_gene1018	3.14e-60	194.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,460DX@72273|Thiotrichales	72273|Thiotrichales	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_523244_2	1123514.KB905899_gene1019	1.62e-189	535.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,45ZT5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_636802_1	1165841.SULAR_01963	9.65e-68	216.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2YNY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_636802_2	506534.Rhein_1119	5.04e-05	47.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X2RR@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_297592_1	866536.Belba_2316	1.41e-68	229.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_127710_1	1380600.AUYN01000007_gene3387	5.14e-89	285.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_1031822_1	321846.PS417_01430	0.000749	42.4	COG0419@1|root,COG0419@2|Bacteria,1Q6FJ@1224|Proteobacteria,1S0MC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23
k59_1031822_2	1249480.B649_11095	2.32e-13	68.6	COG1502@1|root,COG1502@2|Bacteria,1R51A@1224|Proteobacteria,42PGS@68525|delta/epsilon subdivisions,2YNQ6@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
k59_185142_1	1168067.JAGP01000001_gene1678	2.4e-258	713.0	COG1457@1|root,COG1457@2|Bacteria,1NS07@1224|Proteobacteria,1RNHG@1236|Gammaproteobacteria,4638W@72273|Thiotrichales	72273|Thiotrichales	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
k59_241549_1	868864.Dester_1136	0.00018	42.7	COG2838@1|root,COG2838@2|Bacteria,2G3S8@200783|Aquificae	200783|Aquificae	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_241549_2	563040.Saut_1114	6.53e-121	351.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_467464_1	1286632.P278_17140	2.04e-14	72.8	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_467464_2	504487.JCM19302_1725	1.14e-53	170.0	COG2005@1|root,COG2005@2|Bacteria,4NUSR@976|Bacteroidetes,1I43Z@117743|Flavobacteriia	976|Bacteroidetes	S	Transcriptional regulator, LysR	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
k59_467464_3	1178825.ALIH01000002_gene939	1.45e-19	84.7	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1143888_1	225849.swp_3973	8.17e-81	257.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,2Q9F3@267890|Shewanellaceae	1236|Gammaproteobacteria	V	TIGRFAM lipid A ABC exporter family, fused ATPase and inner membrane subunits	draA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1369728_1	1380600.AUYN01000001_gene2264	2.81e-77	243.0	COG1086@1|root,COG1086@2|Bacteria,4P0C8@976|Bacteroidetes,1I7GZ@117743|Flavobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
k59_1766668_1	1250278.JQNQ01000001_gene1711	2.03e-42	143.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_1315146_1	1168034.FH5T_12260	6.26e-71	234.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_14346_1	880070.Cycma_2822	2.86e-11	67.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,47N4D@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_127749_1	411154.GFO_3211	7.94e-102	298.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia	976|Bacteroidetes	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_806261_1	865937.Gilli_0810	3.06e-51	180.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia,2P5FG@244698|Gillisia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
k59_72052_1	411154.GFO_1778	9.87e-225	628.0	COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,1IJMR@117743|Flavobacteriia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
k59_1257319_1	411154.GFO_3349	1.29e-140	404.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1HXA2@117743|Flavobacteriia	976|Bacteroidetes	E	ABC transporter	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_1031868_1	1123228.AUIH01000033_gene2675	1.47e-39	150.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales	135619|Oceanospirillales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1196949_1	929558.SMGD1_0154	3.36e-116	346.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2YMMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1766688_1	886377.Murru_1202	1.49e-148	445.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_636873_1	1565129.JSFF01000004_gene3142	3.19e-134	399.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,2Q96B@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k59_580214_1	411154.GFO_2734	3.69e-105	317.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_972911_1	1178825.ALIH01000015_gene1868	2.53e-37	130.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1I2V8@117743|Flavobacteriia	976|Bacteroidetes	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_467529_1	929558.SMGD1_0785	8.55e-143	422.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_467529_2	563040.Saut_1772	5.44e-65	205.0	COG0583@1|root,COG0583@2|Bacteria,1R8CE@1224|Proteobacteria,42PKW@68525|delta/epsilon subdivisions,2YNJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1766710_1	929558.SMGD1_1863	3.81e-42	141.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2YPZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_1766710_2	929558.SMGD1_1864	5.71e-35	132.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_353384_1	1380600.AUYN01000006_gene386	5.57e-88	265.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,1HWXJ@117743|Flavobacteriia	976|Bacteroidetes	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
k59_1426875_1	929558.SMGD1_0904	1.11e-204	588.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_972926_1	323850.Shew_2618	2.18e-70	222.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1RYMT@1236|Gammaproteobacteria,2QEJT@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1369802_1	1565129.JSFF01000005_gene2293	5.56e-145	421.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,2QAQ4@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1117,iSFxv_1172.SFxv_0621,iS_1188.S0577	Cyt_bd_oxida_I
k59_636909_1	62928.azo2756	6.59e-113	333.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,2KUT9@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1087363_1	391603.FBALC1_10307	9.12e-91	286.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_523358_1	1121931.AUHG01000010_gene162	1.16e-88	281.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_467552_1	1348583.ATLH01000003_gene3883	7.87e-67	225.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,1I3QP@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
k59_467552_2	1122176.KB903576_gene4870	3.71e-92	283.0	COG0436@1|root,COG0436@2|Bacteria,4NJEW@976|Bacteroidetes	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1426902_1	572480.Arnit_0111	4.3e-62	210.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,MASE2,PAS_7
k59_1257394_1	323850.Shew_2128	3.31e-62	211.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,2Q9WF@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM transglutaminase domain protein	tgpA	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_1087385_1	1178825.ALIH01000003_gene2108	2.86e-54	188.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
k59_297733_1	269799.Gmet_1826	2.9e-77	235.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_95949_1	1168034.FH5T_10060	3.82e-97	289.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,2FMWZ@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_772189_1	563040.Saut_0795	1.23e-110	330.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2YMZK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_772189_2	1172190.M947_05185	1.47e-37	130.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,42RSQ@68525|delta/epsilon subdivisions,2YRW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_265151_1	760154.Sulba_1006	5.54e-79	245.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42YRK@68525|delta/epsilon subdivisions,2YRM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
k59_37142_1	929558.SMGD1_0486	3.32e-47	159.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2YNH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_37142_2	1150621.SMUL_2563	2.94e-97	290.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2YNDN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_208892_1	1121931.AUHG01000011_gene2147	3.33e-69	221.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_208892_2	411154.GFO_2232	2.27e-24	101.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
k59_1393469_1	313603.FB2170_06615	2.42e-225	635.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1HXBP@117743|Flavobacteriia	976|Bacteroidetes	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ROK
k59_1393469_2	929562.Emtol_1101	8.33e-21	95.1	COG2755@1|root,COG5434@1|root,COG2755@2|Bacteria,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,47KBB@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	Glyco_hydro_28,Lipase_GDSL_2,Pectate_lyase_3
k59_1790813_1	1137281.D778_01448	2.44e-54	184.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1790813_2	1121912.AUHD01000011_gene768	1.19e-40	145.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
k59_1790813_3	867900.Celly_3012	1.96e-145	422.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia,1F915@104264|Cellulophaga	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
k59_1790813_4	391603.FBALC1_09632	4.8e-79	242.0	COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1HY57@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k59_1733619_1	929558.SMGD1_1301	5.12e-50	167.0	2AIM2@1|root,319HK@2|Bacteria,1Q2ST@1224|Proteobacteria,42W74@68525|delta/epsilon subdivisions,2YQAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1733619_2	929558.SMGD1_1303	3.54e-10	59.7	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,42P6Y@68525|delta/epsilon subdivisions,2YMZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_1790817_1	62928.azo2867	5.7e-76	236.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,2KW3S@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_265191_1	391587.KAOT1_07253	3.4e-20	91.3	COG1540@1|root,COG2049@1|root,COG1540@2|Bacteria,COG2049@2|Bacteria,4NJ86@976|Bacteroidetes,1HY57@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k59_265191_2	1121931.AUHG01000011_gene2246	1.41e-41	143.0	COG2049@1|root,COG2049@2|Bacteria,4NMNT@976|Bacteroidetes,1I1C1@117743|Flavobacteriia	976|Bacteroidetes	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
k59_434512_1	497321.C664_11595	3.83e-162	464.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,2KXYS@206389|Rhodocyclales	206389|Rhodocyclales	G	TRAP-type C4-dicarboxylate transport system, large permease	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1281171_1	1123326.JFBL01000001_gene1295	1.73e-14	72.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,1RGXE@1224|Proteobacteria,42QQW@68525|delta/epsilon subdivisions,2YP1D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the urease beta subunit family	ureA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
k59_1281171_2	367737.Abu_0807	9.33e-13	68.2	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,42NUG@68525|delta/epsilon subdivisions,2YMYA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_151196_1	411154.GFO_2674	2.09e-107	314.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1HYYA@117743|Flavobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_1733662_1	748247.AZKH_4347	1.88e-99	309.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,2KUV3@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1167945_1	1123518.ARWI01000001_gene563	1.21e-142	427.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,45ZQF@72273|Thiotrichales	72273|Thiotrichales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1167958_1	929556.Solca_2235	5.99e-05	45.1	2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1167958_2	1121875.KB907546_gene2671	1.79e-59	186.0	COG2010@1|root,COG2010@2|Bacteria,4NV2A@976|Bacteroidetes,1I5FJ@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1167958_3	694427.Palpr_2927	1.39e-33	127.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,2FWWQ@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
k59_1281220_1	1137281.D778_00757	2.28e-245	678.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1281220_2	1380600.AUYN01000009_gene1782	5.59e-17	80.1	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
k59_151243_1	1123514.KB905902_gene195	4.06e-17	82.8	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,462F9@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_151243_3	90814.KL370892_gene2318	3.96e-24	102.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1SN75@1236|Gammaproteobacteria,462AW@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_209002_1	768066.HELO_3747	6.47e-09	58.2	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales	135619|Oceanospirillales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_209002_2	1268635.Loa_00913	1.1e-35	122.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1JEJ9@118969|Legionellales	118969|Legionellales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
k59_37263_1	504487.JCM19302_932	9.53e-36	124.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1HXAF@117743|Flavobacteriia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_37263_2	1380600.AUYN01000003_gene114	6.86e-12	65.1	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_1281237_1	62928.azo2162	7.1e-20	88.6	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,2KVVG@206389|Rhodocyclales	206389|Rhodocyclales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1281237_2	748247.AZKH_2045	7.61e-87	265.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,2KUAX@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_1562902_1	1178825.ALIH01000004_gene2953	5.87e-180	528.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
k59_265266_1	1121396.KB893012_gene4024	8.5e-38	140.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria,2MIN0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_491195_1	1216967.L100_16075	0.000447	47.8	COG2199@1|root,COG3706@2|Bacteria,4P44V@976|Bacteroidetes	976|Bacteroidetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1508697_1	1286632.P278_32890	5.11e-32	122.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1508697_2	1178825.ALIH01000011_gene40	4.07e-58	191.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1HXHS@117743|Flavobacteriia	976|Bacteroidetes	K	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_434604_1	85643.Tmz1t_3480	6.58e-103	311.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2VH4U@28216|Betaproteobacteria,2KX7R@206389|Rhodocyclales	206389|Rhodocyclales	E	Lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	-
k59_1053950_1	411154.GFO_2195	2.17e-57	188.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,1HYMD@117743|Flavobacteriia	976|Bacteroidetes	S	dehydrogenases and related proteins	gfo	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_265272_1	1329516.JPST01000018_gene2643	4.53e-06	50.8	COG2369@1|root,COG2369@2|Bacteria	2|Bacteria	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F,Phage_min_cap2
k59_265272_4	1500306.JQLA01000006_gene309	1.26e-09	60.1	2EKDT@1|root,33E42@2|Bacteria,1NHUX@1224|Proteobacteria,2UMAJ@28211|Alphaproteobacteria,4BEYK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacteriophage related domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4128
k59_1393634_1	1121931.AUHG01000012_gene2525	5.19e-93	298.0	COG4258@1|root,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
k59_1213679_1	411154.GFO_2862	2.52e-62	199.0	COG0457@1|root,COG0457@2|Bacteria,4NG9G@976|Bacteroidetes,1HYXF@117743|Flavobacteriia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
k59_1213679_2	411154.GFO_2861	1.21e-51	175.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan synthetase	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1790985_1	1123228.AUIH01000022_gene3121	4.87e-70	235.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XJ59@135619|Oceanospirillales	135619|Oceanospirillales	F	Adenylate cyclase, class-I	-	-	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Adenyl_cycl_N,Adenylate_cycl
k59_831197_2	1120951.AUBG01000001_gene943	6.07e-10	57.4	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_719680_1	631362.Thi970DRAFT_02562	3.74e-36	139.0	COG1083@1|root,COG3980@1|root,COG1083@2|Bacteria,COG3980@2|Bacteria,1R8GW@1224|Proteobacteria,1SBXJ@1236|Gammaproteobacteria,1X1HA@135613|Chromatiales	135613|Chromatiales	M	cytidylyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_719680_2	631362.Thi970DRAFT_02561	7.23e-05	45.1	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RNEQ@1236|Gammaproteobacteria,1WXH9@135613|Chromatiales	135613|Chromatiales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_994075_1	1121931.AUHG01000018_gene1352	3.02e-84	258.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_545932_1	1121931.AUHG01000011_gene1967	2.6e-105	314.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_886180_2	709032.Sulku_1311	5.34e-62	196.0	COG2077@1|root,COG2077@2|Bacteria,1Q5WV@1224|Proteobacteria,431ZJ@68525|delta/epsilon subdivisions,2YSAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_1111215_1	1121931.AUHG01000012_gene2623	4.89e-53	179.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1HXRM@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_1111215_2	269798.CHU_2327	1.84e-74	224.0	COG3607@1|root,COG3607@2|Bacteria,4NR86@976|Bacteroidetes,47Q11@768503|Cytophagia	976|Bacteroidetes	S	Extradiol dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_604269_1	1313421.JHBV01000041_gene3418	2.15e-156	462.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IPRD@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_604269_2	1380600.AUYN01000009_gene1333	2.16e-104	320.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1565591_1	1137281.D778_00363	5.28e-158	465.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_1215916_1	458817.Shal_3734	1.17e-56	179.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S3HH@1236|Gammaproteobacteria,2QAJS@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_1215916_2	1229485.AMYV01000029_gene2798	4.78e-32	116.0	COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,1RR4T@1236|Gammaproteobacteria,1J67F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	IV02_24660	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_722341_1	1484460.JSWG01000008_gene2010	6.15e-95	281.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1HXC7@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_722341_2	1137281.D778_02351	2.02e-22	97.4	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes,1HWSH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_8
k59_1565657_1	1123261.AXDW01000032_gene3604	3.49e-23	95.9	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1X3NA@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	deoD	-	2.4.2.44	ko:K19696	ko00270,ko01100,map00270,map01100	-	R09668	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_379336_1	504487.JCM19302_2623	2.23e-32	113.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_379336_2	1484460.JSWG01000009_gene225	4.24e-99	302.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1HWW3@117743|Flavobacteriia	976|Bacteroidetes	D	peptidase M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_98829_1	1248916.ANFY01000005_gene2622	1.64e-08	56.2	2DMQT@1|root,32T2H@2|Bacteria,1N211@1224|Proteobacteria,2UI71@28211|Alphaproteobacteria,2KBZ2@204457|Sphingomonadales	204457|Sphingomonadales	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k59_98829_2	1056820.KB900662_gene3906	9.98e-25	95.9	2B9U6@1|root,32372@2|Bacteria,1RHAQ@1224|Proteobacteria,1S2IH@1236|Gammaproteobacteria,2PQ77@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k59_1056441_1	563040.Saut_1546	1.17e-33	134.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_1396015_2	411154.GFO_3599	9.04e-41	143.0	COG2207@1|root,COG2207@2|Bacteria,4NGI6@976|Bacteroidetes,1HX76@117743|Flavobacteriia	976|Bacteroidetes	K	AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1452635_1	367737.Abu_0573	1.23e-33	124.0	COG2143@1|root,COG2143@2|Bacteria,1NEN3@1224|Proteobacteria,42SXU@68525|delta/epsilon subdivisions,2YPR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
k59_1452635_2	572480.Arnit_1808	8.15e-23	90.9	COG2258@1|root,COG2258@2|Bacteria,1RIAF@1224|Proteobacteria,42VQG@68525|delta/epsilon subdivisions,2YQDM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_1216006_1	1150621.SMUL_3188	1.56e-71	222.0	COG0500@1|root,COG2226@2|Bacteria,1N2SK@1224|Proteobacteria,42U4A@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_663735_1	1172190.M947_10625	3.36e-97	293.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,42MHI@68525|delta/epsilon subdivisions,2YMU8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k59_1056502_1	1026882.MAMP_00862	5.16e-123	365.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,460U9@72273|Thiotrichales	72273|Thiotrichales	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k59_98930_1	493475.GARC_4567	1.09e-68	216.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,465TH@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_1793803_1	563040.Saut_2096	1.64e-116	344.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,42PRR@68525|delta/epsilon subdivisions,2YMYP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	sulfur dehydrogenase subunit	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_833559_1	572480.Arnit_0760	1.28e-234	658.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_548299_1	1123518.ARWI01000001_gene90	3.75e-17	80.5	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,45ZZW@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_56454_3	929558.SMGD1_2288	1.08e-29	111.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2YMD4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_1636192_1	556268.OFAG_01330	3.99e-77	244.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,472YE@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_1016649_1	203122.Sde_2049	1.05e-34	137.0	COG5184@1|root,COG5276@1|root,COG5644@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5644@2|Bacteria,1QX03@1224|Proteobacteria,1T31Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
k59_1016664_1	1123518.ARWI01000001_gene480	4.46e-130	374.0	COG3248@1|root,COG3248@2|Bacteria,1RB5M@1224|Proteobacteria,1TAAB@1236|Gammaproteobacteria,462VM@72273|Thiotrichales	72273|Thiotrichales	M	Nucleoside-binding outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1016664_2	1123518.ARWI01000001_gene481	1.85e-41	148.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,460BY@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1636363_1	1249975.JQLP01000005_gene2582	1.73e-122	358.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HWSK@117743|Flavobacteriia,2P75W@244698|Gillisia	976|Bacteroidetes	S	Acyl transferase	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
k59_1636402_1	1121931.AUHG01000010_gene284	1.05e-56	201.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_1636416_1	62928.azo1328	1.11e-109	330.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,2KUAC@206389|Rhodocyclales	206389|Rhodocyclales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_1636456_1	1209072.ALBT01000008_gene3000	4.74e-06	47.4	28HGQ@1|root,2Z7SH@2|Bacteria,1R6PH@1224|Proteobacteria,1RYGY@1236|Gammaproteobacteria,1FGWA@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1636456_2	1123228.AUIH01000007_gene2569	5.38e-33	118.0	2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,1XKNC@135619|Oceanospirillales	135619|Oceanospirillales	S	type III effector	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
k59_1636493_1	1249975.JQLP01000005_gene1788	2.42e-89	272.0	2C3TS@1|root,332JE@2|Bacteria,4NV6C@976|Bacteroidetes,1I5BY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1636550_1	1172190.M947_02325	1.96e-111	341.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1636550_2	563040.Saut_0744	6.11e-68	208.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SJM@68525|delta/epsilon subdivisions,2YPJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1636550_3	326298.Suden_0726	1.27e-49	158.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2YPU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_958801_1	1123518.ARWI01000001_gene1706	4.04e-131	394.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,461Y3@72273|Thiotrichales	72273|Thiotrichales	H	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1636774_1	211586.SO_4437	6.73e-122	357.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,2QBDP@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_959071_1	391603.FBALC1_07168	1.66e-252	701.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_1636873_1	572480.Arnit_0807	5.24e-71	228.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_959076_1	929558.SMGD1_2643	1.62e-104	325.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_959151_1	1380600.AUYN01000002_gene4	1.73e-44	166.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_1636968_1	1172190.M947_07510	3.68e-65	219.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_959157_1	326298.Suden_1181	5.39e-119	348.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2YM99@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_959179_2	1535422.ND16A_2812	2.65e-46	158.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,2Q6U3@267889|Colwelliaceae	1236|Gammaproteobacteria	O	prohibitin homologues	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_1637032_2	563040.Saut_1918	1.24e-57	187.0	COG1385@1|root,COG1385@2|Bacteria,1QDSD@1224|Proteobacteria,42S1W@68525|delta/epsilon subdivisions,2YP9M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_959242_1	1347342.BN863_2640	2.23e-45	160.0	COG2849@1|root,COG4219@1|root,COG2849@2|Bacteria,COG4219@2|Bacteria,4PNJU@976|Bacteroidetes,1IK7N@117743|Flavobacteriia	976|Bacteroidetes	KT	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_959260_1	1123037.AUDE01000027_gene2097	3.47e-90	287.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_959282_1	1565129.JSFF01000013_gene286	1.2e-42	149.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,2Q9MP@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_959316_1	90814.KL370891_gene1905	8.65e-148	433.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,45ZSS@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_1637240_1	1123514.KB905902_gene247	5.02e-97	302.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,46276@72273|Thiotrichales	72273|Thiotrichales	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_1637262_1	563040.Saut_0767	1.33e-17	80.1	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1637262_2	1172190.M947_09170	5.7e-80	244.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_959472_1	411154.GFO_1028	1.48e-102	301.0	28KSE@1|root,2ZA9S@2|Bacteria,4NKV8@976|Bacteroidetes,1I1N7@117743|Flavobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
k59_1237068_1	745718.JADT01000020_gene279	1.67e-252	694.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
k59_1237068_2	1380600.AUYN01000012_gene3005	4.63e-39	140.0	COG0859@1|root,COG0859@2|Bacteria,4NFVU@976|Bacteroidetes,1HXFI@117743|Flavobacteriia	976|Bacteroidetes	M	heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_959507_1	1232683.ADIMK_0730	8.87e-160	453.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,46585@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Putrescine transport system permease	-	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
k59_959507_2	1122201.AUAZ01000009_gene2768	6.89e-33	121.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,46461@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1177 ABC-type spermidine putrescine transport system, permease component II	potI	-	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
k59_1637417_1	572480.Arnit_0602	1.17e-46	168.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42QY3@68525|delta/epsilon subdivisions,2YNZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,MCPsignal,dCache_2,sCache_2
k59_1637467_1	392500.Swoo_0503	2.19e-34	130.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,2QARI@267890|Shewanellaceae	1236|Gammaproteobacteria	L	DEAD DEAH box helicase domain protein	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
k59_1637578_1	1123518.ARWI01000001_gene1961	2.51e-108	324.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,45ZXR@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1637578_2	1123514.KB905901_gene128	1.25e-14	70.9	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria	1224|Proteobacteria	S	PFAM DUF218 domain	ycbC	GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	DUF218
k59_1637634_1	864702.OsccyDRAFT_1941	4.91e-24	99.4	COG0516@1|root,COG0516@2|Bacteria,1G1MX@1117|Cyanobacteria,1H94E@1150|Oscillatoriales	1117|Cyanobacteria	F	IMP dehydrogenase GMP reductase	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
k59_1637663_1	1120966.AUBU01000003_gene1280	7.35e-32	129.0	COG0642@1|root,COG2205@2|Bacteria,4P15P@976|Bacteroidetes,47XWZ@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12
k59_959803_1	1123514.KB905899_gene2040	1.76e-83	259.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,460PI@72273|Thiotrichales	72273|Thiotrichales	H	HemY protein N-terminus	-	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
k59_959803_2	1123518.ARWI01000001_gene1314	2.44e-109	337.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	ydaK	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_959803_3	1123514.KB905899_gene2039	1.94e-28	109.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,461PX@72273|Thiotrichales	72273|Thiotrichales	M	phospholipase A1	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_1237447_1	156578.ATW7_11115	2.41e-26	106.0	COG4916@1|root,COG4916@2|Bacteria,1RM3P@1224|Proteobacteria	1224|Proteobacteria	K	protein containing a TIR (Toll-Interleukin 1-resistance) domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_1582452_1	563040.Saut_1236	1.35e-84	274.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,42M8I@68525|delta/epsilon subdivisions,2YN4J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_1187096_1	1178825.ALIH01000017_gene687	0.0	1054.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_396325_2	1415778.JQMM01000001_gene1021	1.7e-56	192.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1J4EU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
k59_1300073_1	1137281.D778_00534	2.01e-30	115.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1HY13@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1300073_2	313603.FB2170_00895	3.2e-137	395.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,1HYGY@117743|Flavobacteriia,2PGU1@252356|Maribacter	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
k59_1300073_3	1380600.AUYN01000001_gene2932	7.37e-97	308.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_1469275_1	317025.Tcr_0750	1.32e-103	318.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_622260_1	1380600.AUYN01000003_gene244	1.68e-85	274.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_622260_2	1347342.BN863_4780	5.6e-71	223.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,1HXRN@117743|Flavobacteriia	976|Bacteroidetes	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_948_1	1235457.C404_16500	2.54e-53	172.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,1KFG6@119060|Burkholderiaceae	28216|Betaproteobacteria	C	formate dehydrogenase	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
k59_948_2	1235457.C404_16505	2.17e-78	257.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,1K5NF@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_791659_1	1178825.ALIH01000015_gene1880	1.64e-39	135.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1I185@117743|Flavobacteriia	976|Bacteroidetes	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_791659_2	746697.Aeqsu_0613	7.31e-35	128.0	2B7X4@1|root,32143@2|Bacteria,4NNUI@976|Bacteroidetes,1I2MC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_1582476_1	1121931.AUHG01000011_gene1900	8.66e-58	199.0	COG0457@1|root,COG0526@1|root,COG0457@2|Bacteria,COG0526@2|Bacteria,4NKFI@976|Bacteroidetes,1HZXV@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
k59_735203_1	575564.HMPREF0014_00028	2.58e-34	129.0	COG4641@1|root,COG4641@2|Bacteria,1RD4C@1224|Proteobacteria,1RYDA@1236|Gammaproteobacteria,3NKBK@468|Moraxellaceae	1236|Gammaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
k59_791662_1	563040.Saut_0526	1.19e-118	342.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	cprR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_791662_2	929558.SMGD1_1781	4.48e-160	469.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_1469291_1	1123514.KB905899_gene1886	1.4e-128	376.0	COG0189@1|root,COG0189@2|Bacteria,1RACB@1224|Proteobacteria,1S30U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_791668_1	598467.BrE312_2782	1.27e-14	67.0	2EG32@1|root,339V1@2|Bacteria,1NPP4@1224|Proteobacteria,1SH2K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1017702_1	90814.KL370891_gene382	7.69e-95	291.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,46016@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_283288_1	1121931.AUHG01000019_gene2989	2.61e-10	58.9	2CPY4@1|root,32SK3@2|Bacteria,4NTVY@976|Bacteroidetes,1I490@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
k59_283288_2	1121931.AUHG01000019_gene2991	2.36e-89	269.0	COG2197@1|root,COG2197@2|Bacteria,4NTTS@976|Bacteroidetes,1I4ZR@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1300123_1	1121931.AUHG01000010_gene148	4.29e-69	213.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_1300123_2	1121931.AUHG01000010_gene147	2.31e-44	152.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1HXAJ@117743|Flavobacteriia	976|Bacteroidetes	S	succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_396376_2	1033802.SSPSH_002227	2.75e-14	72.0	2978X@1|root,2ZUGN@2|Bacteria,1NM3Z@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_283292_1	929558.SMGD1_0459	2.54e-113	354.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_226921_1	1353276.JADR01000005_gene2523	4.28e-94	282.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,1HYJI@117743|Flavobacteriia	976|Bacteroidetes	GM	Transport permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
k59_226921_2	983544.Lacal_0124	1.48e-181	518.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1HXJV@117743|Flavobacteriia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_226921_3	1189620.AJXL01000129_gene1684	7.1e-66	215.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	XK27_03530	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,rRNA_methylase
k59_226921_4	990285.RGCCGE502_14925	8.64e-05	46.2	COG1215@1|root,COG1215@2|Bacteria,1RCNS@1224|Proteobacteria,2U62E@28211|Alphaproteobacteria,4BM9S@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyltransferases involved in cell wall biogenesis	exoU	-	-	ko:K16564	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_113954_1	557393.B8QTW4_9CAUD	8.31e-37	140.0	4QAMU@10239|Viruses,4QV4U@35237|dsDNA viruses  no RNA stage,4QPEV@28883|Caudovirales,4QI0J@10662|Myoviridae	10662|Myoviridae	S	Baseplate J-like protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025	-	-	-	-	-	-	-	-	-	-	-
k59_1413145_1	1249975.JQLP01000001_gene3404	1.09e-167	489.0	COG0028@1|root,COG0028@2|Bacteria,4NH3H@976|Bacteroidetes,1HYIZ@117743|Flavobacteriia,2P758@244698|Gillisia	976|Bacteroidetes	EH	Thiamine pyrophosphate enzyme, central domain	poxB	-	1.2.5.1,2.2.1.6	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03145,R04672,R04673,R08648	RC00027,RC00106,RC00860,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_678820_1	572480.Arnit_1911	2.49e-91	278.0	COG5002@1|root,COG5002@2|Bacteria,1QZ29@1224|Proteobacteria,43CEG@68525|delta/epsilon subdivisions,2YTC2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_283319_1	1380384.JADN01000004_gene2051	6.53e-127	369.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M43	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
k59_283319_2	1121887.AUDK01000003_gene2750	1.17e-34	124.0	COG3187@1|root,COG3187@2|Bacteria,4NQIA@976|Bacteroidetes,1I5JP@117743|Flavobacteriia,2NWE5@237|Flavobacterium	976|Bacteroidetes	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4377,META
k59_283319_3	1178825.ALIH01000001_gene2293	1.08e-30	110.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_283328_2	929558.SMGD1_1860	7.06e-36	135.0	COG2885@1|root,COG2885@2|Bacteria,1R9HA@1224|Proteobacteria,42T44@68525|delta/epsilon subdivisions,2YQQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_1187214_1	367737.Abu_1240	6.8e-13	70.1	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1066_1	572480.Arnit_0335	1.28e-90	275.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,42PAG@68525|delta/epsilon subdivisions,2YTPC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k59_123344_2	90813.JQMT01000001_gene967	1.73e-10	63.9	COG3115@1|root,COG3115@2|Bacteria,1NMX8@1224|Proteobacteria,1SIUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	-	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
k59_1479115_1	1380600.AUYN01000009_gene1910	1.33e-137	395.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1479115_2	1380600.AUYN01000009_gene1909	4.39e-135	386.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1HY0K@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1479115_3	1121912.AUHD01000009_gene3722	2.27e-15	73.6	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1HXQK@117743|Flavobacteriia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
k59_744607_1	1121931.AUHG01000016_gene976	1.78e-137	403.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1027740_1	1168067.JAGP01000001_gene465	4.35e-36	131.0	COG1434@1|root,COG1434@2|Bacteria,1N8RS@1224|Proteobacteria,1SDWN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_1027740_2	90813.JQMT01000001_gene684	1.11e-96	290.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria,461HV@72273|Thiotrichales	72273|Thiotrichales	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_180578_1	1123518.ARWI01000001_gene72	8.85e-114	347.0	COG0428@1|root,COG2905@1|root,COG0428@2|Bacteria,COG2905@2|Bacteria,1QE6Q@1224|Proteobacteria,1S080@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	cNMP_binding
k59_1365344_1	326298.Suden_0935	1.68e-51	169.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,43AMB@68525|delta/epsilon subdivisions,2YT1W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_1365344_2	387093.SUN_1298	5.2e-11	61.6	COG1227@1|root,COG1227@2|Bacteria,1P9JN@1224|Proteobacteria,42N0W@68525|delta/epsilon subdivisions,2YNNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
k59_237159_1	1347342.BN863_5280	5.16e-51	169.0	COG1215@1|root,COG1215@2|Bacteria,4NFXI@976|Bacteroidetes,1HXPW@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_237159_2	1178825.ALIH01000001_gene2555	5.21e-106	307.0	COG2227@1|root,COG2227@2|Bacteria,4NM91@976|Bacteroidetes,1HZAR@117743|Flavobacteriia	976|Bacteroidetes	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_237159_3	1484460.JSWG01000008_gene2036	3.72e-42	147.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1HX81@117743|Flavobacteriia	976|Bacteroidetes	I	synthase	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1705250_1	1538295.JY96_19660	9.87e-79	261.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,2WGI2@28216|Betaproteobacteria,1KK2U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EI	Allophanate hydrolase subunit 2	uca	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1422531_1	929558.SMGD1_1193	3.37e-33	124.0	COG2199@1|root,COG2199@2|Bacteria,1QZ2R@1224|Proteobacteria,43CET@68525|delta/epsilon subdivisions,2YTCA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1422531_2	929558.SMGD1_1194	7.34e-87	258.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2YMBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_575585_1	929558.SMGD1_2813	4.42e-15	72.8	COG0671@1|root,COG0671@2|Bacteria,1N7CW@1224|Proteobacteria,42VJN@68525|delta/epsilon subdivisions,2YQBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_575585_2	929558.SMGD1_2814	3.19e-132	388.0	COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
k59_969718_1	504487.JCM19302_1949	9.39e-77	242.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1HWJU@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_969718_2	1380600.AUYN01000003_gene210	6.55e-27	100.0	COG0241@1|root,COG0241@2|Bacteria,4PKR5@976|Bacteroidetes,1IJCZ@117743|Flavobacteriia	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1422532_1	1122176.KB903537_gene1608	0.00016	50.1	COG2931@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
k59_237176_1	318464.IO99_14910	5.67e-32	122.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,36FFE@31979|Clostridiaceae	186801|Clostridia	S	domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
k59_1648965_1	1121912.AUHD01000003_gene2990	4e-06	47.8	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1HWWV@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1648965_2	655815.ZPR_2938	1.04e-291	815.0	COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,1HXMX@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_1648965_3	504487.JCM19302_3949	1.97e-70	213.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1648965_4	1380600.AUYN01000007_gene3273	1.56e-66	207.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_10324_1	880073.Calab_1611	6.98e-15	73.6	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_10324_2	99598.Cal7507_4821	3.24e-11	67.4	COG2197@1|root,COG2197@2|Bacteria,1G0N8@1117|Cyanobacteria,1HKG2@1161|Nostocales	1117|Cyanobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_914122_1	1380600.AUYN01000006_gene280	1.5e-109	337.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_801876_1	1123518.ARWI01000001_gene347	1.09e-120	355.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,45ZZ7@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_180616_2	1123514.KB905899_gene934	2.16e-168	495.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,4604N@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1763598_1	317025.Tcr_1115	2.02e-172	513.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,4602D@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_350431_1	1121912.AUHD01000007_gene479	1.11e-57	197.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_350431_2	1380600.AUYN01000001_gene2652	3.86e-147	424.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HWZ1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
k59_11714_1	425104.Ssed_2335	1.9e-45	146.0	2E5H5@1|root,3308N@2|Bacteria,1NB87@1224|Proteobacteria,1SDHI@1236|Gammaproteobacteria,2QCJ6@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2788
k59_11714_2	637905.SVI_2034	1.33e-46	150.0	2DB8J@1|root,32TX0@2|Bacteria,1MZBR@1224|Proteobacteria,1S9W6@1236|Gammaproteobacteria,2QCB6@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM CopG domain protein DNA-binding domain protein	ybfE	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	-	-	-	-	-	-	-	-	-	RHH_1
k59_1366871_1	1380600.AUYN01000009_gene1320	3.63e-140	412.0	COG2304@1|root,COG2304@2|Bacteria,4NFNQ@976|Bacteroidetes,1I0RD@117743|Flavobacteriia	976|Bacteroidetes	S	Von Willebrand factor A	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
k59_1029055_1	1168067.JAGP01000001_gene2069	9.97e-44	157.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,45ZQ4@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1029055_2	1168067.JAGP01000001_gene2068	1.1e-40	134.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,4618M@72273|Thiotrichales	72273|Thiotrichales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_1029055_3	1117647.M5M_11185	7.37e-09	58.9	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1J4EF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1519 3-deoxy-D-manno-octulosonic-acid transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
k59_1706942_2	929558.SMGD1_2857	3.15e-71	221.0	2A4DJ@1|root,30SZD@2|Bacteria,1PCJ7@1224|Proteobacteria,430CF@68525|delta/epsilon subdivisions,2YRYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182197_1	1123518.ARWI01000001_gene1948	5.77e-121	360.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1536632_1	1121912.AUHD01000005_gene1691	1.16e-126	373.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_1312087_1	572480.Arnit_0090	5.23e-116	353.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2YN94@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1480870_1	1165841.SULAR_02323	5.82e-52	173.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1480870_2	929558.SMGD1_1107	2e-67	228.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_690819_1	1123228.AUIH01000042_gene2995	3.3e-87	273.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,1XJBE@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1029080_1	1380600.AUYN01000006_gene537	1.72e-72	226.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
k59_520268_1	1191523.MROS_0771	5.59e-61	202.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1536656_1	1250278.JQNQ01000001_gene3297	4.05e-64	207.0	2DBB7@1|root,2Z85R@2|Bacteria,4NJNG@976|Bacteroidetes,1I15F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1594442_1	1123234.AUKI01000019_gene587	9.06e-209	582.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1HWMU@117743|Flavobacteriia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_633843_1	1380600.AUYN01000003_gene92	1.57e-177	526.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_577262_1	504487.JCM19302_511	7.2e-36	131.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1HX0C@117743|Flavobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
k59_577262_2	655815.ZPR_3723	2.51e-44	154.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1HYAU@117743|Flavobacteriia	976|Bacteroidetes	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
k59_1312110_1	1250005.PHEL85_3176	9.55e-172	514.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia,3VWZU@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_69038_1	908819.A0A0A0YNQ8_9CAUD	2.15e-100	316.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales	28883|Caudovirales	S	N-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1763661_1	90814.KL370891_gene1654	2.2e-130	376.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,460CS@72273|Thiotrichales	72273|Thiotrichales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_520280_1	929558.SMGD1_2349	1.32e-14	73.2	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2YM8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_520280_2	563040.Saut_1417	3.79e-56	184.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2YMEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_746255_1	1116482.K9L5M2_9CAUD	1.67e-11	68.9	4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPUI@28883|Caudovirales,4QIGP@10662|Myoviridae	10662|Myoviridae	S	Clp protease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_746255_2	1122218.KB893654_gene1828	2.96e-22	95.5	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,1JUHQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_633858_1	1380600.AUYN01000006_gene673	1.21e-26	108.0	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
k59_633858_3	504487.JCM19302_3903	8.23e-188	538.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_1141225_1	717772.THIAE_05230	1.7e-09	62.4	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,460ES@72273|Thiotrichales	72273|Thiotrichales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340,ko:K12538	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00328,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,1.B.17.1,2.A.6.2	-	-	OEP
k59_1141225_2	90814.KL370891_gene1177	7.24e-84	251.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,460U2@72273|Thiotrichales	72273|Thiotrichales	S	CYTH	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
k59_1141225_3	1123514.KB905899_gene906	4.87e-141	403.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,46065@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1594466_1	1123518.ARWI01000001_gene1476	4.02e-62	203.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,45ZQ5@72273|Thiotrichales	72273|Thiotrichales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_1594466_2	1123518.ARWI01000001_gene1480	5.76e-31	113.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,461AH@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1949)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k59_746262_1	203122.Sde_2033	3.19e-22	94.7	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464DJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_746262_2	873517.HMPREF1977_1608	4.14e-20	87.4	COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,1I2BV@117743|Flavobacteriia,1ERRT@1016|Capnocytophaga	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_407738_1	1172190.M947_11450	2.55e-100	307.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42PNF@68525|delta/epsilon subdivisions,2YNCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_690871_1	572480.Arnit_2501	1.59e-115	349.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_124914_1	1392490.JHZX01000001_gene941	1.43e-88	262.0	2DBG7@1|root,2Z92S@2|Bacteria,4PKHU@976|Bacteroidetes,1IJ9H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182282_1	305700.B447_08423	1.81e-47	165.0	COG3240@1|root,COG3240@2|Bacteria,1MWDI@1224|Proteobacteria,2VTBY@28216|Betaproteobacteria,2KXBE@206389|Rhodocyclales	206389|Rhodocyclales	I	GDSL-like Lipase/Acylhydrolase	-	-	-	ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Lipase_GDSL,VPEP
k59_407758_1	1123518.ARWI01000001_gene1773	1.33e-88	288.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462CG@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM
k59_1029145_1	1565129.JSFF01000012_gene592	2.41e-53	180.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,2Q9K9@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1029146_1	629265.PMA4326_28697	3e-22	97.4	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1Z9JZ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_1312176_1	1123518.ARWI01000001_gene189	2.07e-59	191.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,45ZR3@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1312176_2	1123514.KB905899_gene990	1.98e-157	464.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4601S@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_577342_1	90814.KL370891_gene180	5.36e-129	370.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,45ZUF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_577342_2	1123518.ARWI01000001_gene1095	2.6e-72	237.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RNN3@1236|Gammaproteobacteria,4608U@72273|Thiotrichales	72273|Thiotrichales	P	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_294782_1	1121931.AUHG01000011_gene1988	2.81e-114	359.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_350558_1	1347342.BN863_20660	8.02e-21	90.9	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
k59_350558_2	1178825.ALIH01000007_gene1608	1.1e-32	114.0	COG3360@1|root,COG3360@2|Bacteria,4NURJ@976|Bacteroidetes,1I534@117743|Flavobacteriia	976|Bacteroidetes	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_350558_3	1380600.AUYN01000009_gene992	7.88e-48	161.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k59_1424101_1	572480.Arnit_1346	1.71e-79	258.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
k59_1424101_2	572480.Arnit_1345	3.54e-34	130.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2YR4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Hydrolase_4
k59_1380074_1	313603.FB2170_13613	7.77e-12	63.2	COG3279@1|root,COG3279@2|Bacteria,4NFN4@976|Bacteroidetes,1HYAZ@117743|Flavobacteriia,2PGVM@252356|Maribacter	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_1436964_1	929558.SMGD1_1798	2.44e-25	100.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42RBN@68525|delta/epsilon subdivisions,2YP23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1777712_1	323850.Shew_3082	3.17e-91	281.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,2Q9HH@267890|Shewanellaceae	1236|Gammaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K11914	-	-	-	-	ko00000,ko02044,ko03000	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_308333_1	483215.BACFIN_06748	4.16e-59	192.0	COG1277@1|root,COG1277@2|Bacteria,4NGAT@976|Bacteroidetes,2FP5B@200643|Bacteroidia,4AMG3@815|Bacteroidaceae	976|Bacteroidetes	S	COG COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
k59_82682_1	929558.SMGD1_0640	6.51e-43	153.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_82682_2	563040.Saut_0588	3.42e-52	170.0	2BTJ1@1|root,32NRK@2|Bacteria,1Q3XC@1224|Proteobacteria,42RS4@68525|delta/epsilon subdivisions,2YPVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_1664148_1	1237149.C900_01071	9.36e-111	332.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_647335_1	929558.SMGD1_0556	5.31e-170	484.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_647335_2	563040.Saut_0794	8.65e-68	207.0	2AJGA@1|root,31A2S@2|Bacteria,1Q4T9@1224|Proteobacteria,42ZUF@68525|delta/epsilon subdivisions,2YRSU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_24546_1	1232410.KI421421_gene3547	2.59e-84	257.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,43S3H@69541|Desulfuromonadales	28221|Deltaproteobacteria	EF	Phosphoribosyl synthetase-associated domain	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
k59_1042428_1	1056820.KB900696_gene4073	3.15e-21	93.6	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,2PNHX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	N	Rod binding protein	flgJ	GO:0003674,GO:0005198	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k59_817612_1	497321.C664_14998	1.02e-118	353.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KVW1@206389|Rhodocyclales	206389|Rhodocyclales	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1720572_1	1178825.ALIH01000007_gene1691	1.84e-187	529.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1HXJC@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1720572_2	1380600.AUYN01000009_gene1197	8.24e-200	585.0	COG0460@1|root,COG0527@1|root,COG2021@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,COG2021@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Abhydrolase_1,Homoserine_dh,NAD_binding_3
k59_1326242_1	459349.CLOAM0864	1.03e-09	59.3	COG0771@1|root,COG0771@2|Bacteria,2NPCH@2323|unclassified Bacteria	2|Bacteria	M	Mur ligase middle domain	murD	-	6.3.2.9	ko:K01925,ko:K01932	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1326242_2	945713.IALB_2726	1.48e-22	97.1	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,Peptidase_M66,fn3
k59_1204743_2	929558.SMGD1_0076	2.57e-138	411.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_1549744_1	392500.Swoo_4125	1e-44	160.0	COG3637@1|root,COG3637@2|Bacteria,1R4GF@1224|Proteobacteria,1RPKW@1236|Gammaproteobacteria,2QD9P@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_1204750_1	1304888.ATWF01000001_gene2471	3.79e-50	164.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gspG	-	-	ko:K02246,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_647394_1	1178825.ALIH01000007_gene1625	2.43e-108	322.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_82761_1	90814.KL370891_gene533	6.68e-43	141.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,4612Q@72273|Thiotrichales	72273|Thiotrichales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_82761_2	90814.KL370891_gene534	1.93e-155	443.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,45ZN0@72273|Thiotrichales	72273|Thiotrichales	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1380167_2	926559.JoomaDRAFT_0085	6.13e-16	73.6	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_591914_1	1197477.IA57_01630	0.000855	42.4	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_591914_2	1178825.ALIH01000017_gene671	3.29e-72	226.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia	976|Bacteroidetes	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_535762_1	1165841.SULAR_10709	0.000689	43.1	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_535762_2	1172190.M947_05415	2.17e-47	157.0	COG2258@1|root,COG2258@2|Bacteria,1PWYA@1224|Proteobacteria,42WW0@68525|delta/epsilon subdivisions,2YRT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_535762_3	387093.SUN_0054	7.78e-30	113.0	COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,42XFS@68525|delta/epsilon subdivisions,2YSK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_1205731_1	1278309.KB907101_gene365	4.14e-47	157.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,1S4K8@1236|Gammaproteobacteria,1XKBA@135619|Oceanospirillales	135619|Oceanospirillales	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
k59_1438669_1	1121896.JMLU01000008_gene1780	1.14e-31	129.0	COG4409@1|root,COG4409@2|Bacteria,4PM7K@976|Bacteroidetes,1IJKJ@117743|Flavobacteriia,2NTU2@237|Flavobacterium	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10,fn3
k59_1551388_1	504487.JCM19302_2789	5.55e-90	274.0	COG1835@1|root,COG1835@2|Bacteria,4NPW5@976|Bacteroidetes,1I2NH@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1099525_1	411154.GFO_1551	2.96e-83	259.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_760955_1	411154.GFO_1966	1.79e-21	92.4	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_760955_2	411154.GFO_1967	1.33e-129	381.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HXGY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_1779539_2	411154.GFO_0780	1.19e-62	199.0	COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,1HXZW@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_139667_1	929558.SMGD1_2116	3.88e-58	200.0	COG1196@1|root,COG1196@2|Bacteria,1QEEI@1224|Proteobacteria,43DPF@68525|delta/epsilon subdivisions,2YRNC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1044136_1	319224.Sputcn32_3666	1.12e-78	242.0	COG4607@1|root,COG4607@2|Bacteria,1QYZD@1224|Proteobacteria	1224|Proteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_310141_1	497321.C664_19901	1.18e-114	336.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,2KYAW@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1610585_1	313596.RB2501_07295	1.01e-142	419.0	COG0446@1|root,COG0446@2|Bacteria,4NER5@976|Bacteroidetes,1HYF3@117743|Flavobacteriia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1610585_2	313596.RB2501_07290	2.61e-39	145.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1722329_1	1296415.JACC01000015_gene826	8.94e-115	345.0	COG4147@1|root,COG4147@2|Bacteria,4NHPT@976|Bacteroidetes,1HXQN@117743|Flavobacteriia,2YHN0@290174|Aquimarina	976|Bacteroidetes	S	Sodium:solute symporter family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_930354_1	1047013.AQSP01000067_gene2197	4.27e-09	58.9	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_930354_2	1301098.PKB_3055	1.54e-23	91.7	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3,Cupin_7,Globin
k59_26259_1	326298.Suden_0524	1.27e-39	144.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2YMUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_26259_2	929558.SMGD1_1901	2.55e-112	333.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QYV@68525|delta/epsilon subdivisions,2YNW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Jag_N	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N
k59_1099593_1	1380600.AUYN01000001_gene2219	1.29e-226	634.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,1HYF9@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_649157_1	1121931.AUHG01000012_gene2844	1.14e-97	291.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_310171_2	929558.SMGD1_0575	2.25e-39	131.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2YPTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_365469_1	1380600.AUYN01000010_gene905	8.71e-120	356.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1HYKQ@117743|Flavobacteriia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k59_139749_1	1353528.DT23_01515	9.12e-92	271.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,2XM1S@285107|Thioclava	28211|Alphaproteobacteria	EH	Anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_310201_1	323850.Shew_0727	3.1e-34	130.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,2QB1T@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	styS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
k59_1665958_1	572480.Arnit_3085	9.41e-193	542.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1156184_1	411154.GFO_0103	2.08e-141	409.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_1610656_1	411154.GFO_3472	1.37e-37	136.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,1HYIN@117743|Flavobacteriia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1610656_2	1121931.AUHG01000010_gene487	1.92e-67	224.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1665960_1	1178825.ALIH01000015_gene1903	6.65e-173	508.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k59_1496768_2	929558.SMGD1_0556	3.03e-42	149.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2YNFK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_1722403_1	572480.Arnit_2092	3.89e-91	283.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_139776_1	1395571.TMS3_0121965	3.08e-122	363.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_197665_2	983544.Lacal_1829	2.17e-90	280.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1665968_1	572480.Arnit_2688	1.77e-124	357.0	COG5285@1|root,COG5285@2|Bacteria,1RC3C@1224|Proteobacteria,42R8R@68525|delta/epsilon subdivisions,2YNW8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
k59_26327_1	944546.ABED_0619	5.98e-32	118.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,42QRM@68525|delta/epsilon subdivisions,2YTCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_365519_1	572480.Arnit_0365	1.33e-188	549.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1MV9F@1224|Proteobacteria,42NS1@68525|delta/epsilon subdivisions,2YTPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
k59_254664_1	1249975.JQLP01000005_gene764	4.51e-59	195.0	COG0582@1|root,COG0582@2|Bacteria,4PMIQ@976|Bacteroidetes,1IJUK@117743|Flavobacteriia,2P7EP@244698|Gillisia	976|Bacteroidetes	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_649240_1	335284.Pcryo_2501	8.53e-80	246.0	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,3NPWQ@468|Moraxellaceae	1236|Gammaproteobacteria	S	Sucrose-6F-phosphate phosphohydrolase	yedP	-	2.7.1.31,3.1.3.70	ko:K07026,ko:K15918	ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200	M00532	R01514,R05790	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3,S6PP
k59_1269854_1	1123514.KB905899_gene527	9.93e-32	120.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_1666017_1	563040.Saut_2109	1.19e-83	261.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_197719_1	1443665.JACA01000121_gene1750	1.31e-10	63.9	COG0664@1|root,COG0664@2|Bacteria,4NKFZ@976|Bacteroidetes,1HYDY@117743|Flavobacteriia,2YKER@290174|Aquimarina	976|Bacteroidetes	T	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_1438852_1	1123518.ARWI01000001_gene995	3.3e-206	583.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,45ZTY@72273|Thiotrichales	72273|Thiotrichales	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
k59_1438852_2	1123518.ARWI01000001_gene994	1.82e-43	153.0	COG1735@1|root,COG1735@2|Bacteria,1R149@1224|Proteobacteria,1T4US@1236|Gammaproteobacteria,463WX@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
k59_819542_2	1123514.KB905899_gene539	1.22e-72	241.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1438855_1	326298.Suden_0005	1.93e-73	235.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2YMGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k59_1381979_1	323850.Shew_2936	3.78e-123	359.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,2QAQ9@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_197735_2	1178825.ALIH01000019_gene1220	4.15e-42	140.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_1722496_1	563040.Saut_1092	1.04e-67	207.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2YP7A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetolactate synthase	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_1722496_2	929558.SMGD1_2624	6.18e-90	279.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2YMQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1610760_1	929558.SMGD1_1250	4.4e-85	268.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,42M47@68525|delta/epsilon subdivisions,2YMRS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_26407_1	1123514.KB905899_gene1885	1.87e-90	277.0	COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,1RZEP@1236|Gammaproteobacteria,461N1@72273|Thiotrichales	72273|Thiotrichales	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
k59_1551627_1	1123517.JOMR01000001_gene272	2.33e-33	132.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k59_761186_1	929558.SMGD1_2819	6.19e-36	144.0	COG0419@1|root,COG0419@2|Bacteria,1Q57D@1224|Proteobacteria,42NIY@68525|delta/epsilon subdivisions,2YNHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	P-loop containing region of AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_874819_1	1380600.AUYN01000009_gene1249	1.28e-81	247.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k59_874819_2	1380600.AUYN01000009_gene1248	9.18e-82	254.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1722517_1	1380600.AUYN01000006_gene608	4.57e-269	770.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26435_1	1123517.JOMR01000001_gene1355	1.17e-66	219.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RQI2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-associated metal-dependent hydrolase	cptA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016776,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K19353	ko00540,map00540	-	-	-	ko00000,ko00001,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k59_1551651_1	323850.Shew_2113	1.99e-55	179.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,2Q9BH@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Methyltransferase type 11	yafS	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_268727_1	216432.CA2559_03010	1.55e-97	297.0	28ID4@1|root,2Z8FC@2|Bacteria,4NFYZ@976|Bacteroidetes,1HXPK@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_268727_2	1380600.AUYN01000007_gene3072	7.18e-145	411.0	COG1131@1|root,COG1131@2|Bacteria,4NDV7@976|Bacteroidetes,1HWXK@117743|Flavobacteriia	976|Bacteroidetes	V	ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1397390_1	1565129.JSFF01000012_gene489	1.79e-91	269.0	COG3005@1|root,COG3005@2|Bacteria,1N2Q8@1224|Proteobacteria,1SBFU@1236|Gammaproteobacteria,2QAR2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM NapC NirT cytochrome c domain protein	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
k59_1397390_2	392500.Swoo_4614	9.37e-35	123.0	COG1246@1|root,COG1246@2|Bacteria,1QVUT@1224|Proteobacteria,1T2JM@1236|Gammaproteobacteria,2QEUP@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Putative thioesterase (yiiD_Cterm)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
k59_213339_1	929558.SMGD1_2623	5.97e-121	369.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_100553_1	1380600.AUYN01000012_gene2978	2.44e-87	259.0	2CEU1@1|root,32S0H@2|Bacteria,4NM9W@976|Bacteroidetes,1I2DG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100553_2	1380600.AUYN01000012_gene2979	3.86e-55	174.0	2AV0G@1|root,31KQA@2|Bacteria,4NSIU@976|Bacteroidetes,1I3W6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100553_3	1392490.JHZX01000001_gene95	9.9e-51	164.0	COG3093@1|root,COG3093@2|Bacteria,4NSDG@976|Bacteroidetes,1I3X0@117743|Flavobacteriia	976|Bacteroidetes	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Phage_CI_repr
k59_1345868_1	563040.Saut_1668	1.68e-167	482.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2YMUQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_999895_1	929558.SMGD1_0543	3.1e-77	246.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2YMB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iIT341.HP1532	GATase_6,SIS
k59_999900_2	1380600.AUYN01000009_gene978	2.97e-116	338.0	29WBK@1|root,30HX5@2|Bacteria,4NMWM@976|Bacteroidetes,1I1KG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_999900_3	1380600.AUYN01000009_gene979	1.29e-65	206.0	COG1999@1|root,COG1999@2|Bacteria,4NGHC@976|Bacteroidetes,1HXW6@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	ypmQ	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1117121_1	1353528.DT23_03670	1.92e-128	372.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,2XM9V@285107|Thioclava	28211|Alphaproteobacteria	FP	Exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_214902_1	998088.B565_0057	7.9e-69	221.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1Y425@135624|Aeromonadales	135624|Aeromonadales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_551232_1	563040.Saut_0919	4.9e-114	342.0	COG0539@1|root,COG1107@1|root,COG0539@2|Bacteria,COG1107@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_666929_1	674977.VMC_14590	6.54e-52	174.0	COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria,1XVU7@135623|Vibrionales	135623|Vibrionales	M	Chain length determinant protein	wzz	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_1796949_1	1172190.M947_08890	5.83e-67	213.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,43D3D@68525|delta/epsilon subdivisions,2YTG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1683212_1	357809.Cphy_1738	3.45e-16	84.3	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,21ZDC@1506553|Lachnoclostridium	186801|Clostridia	O	TIGRFAM NiFe hydrogenase maturation protein HypF	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1683212_2	760192.Halhy_4351	4.34e-73	229.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,1IRKA@117747|Sphingobacteriia	976|Bacteroidetes	O	SPTR Hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_944925_1	511062.GU3_08850	2.55e-22	97.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RYFX@1236|Gammaproteobacteria,1Y57H@135624|Aeromonadales	135624|Aeromonadales	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
k59_778450_1	945713.IALB_1461	1.23e-66	208.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1345928_1	929558.SMGD1_1456	5.33e-137	395.0	COG2199@1|root,COG3706@2|Bacteria,1QZZG@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS,PAS_3,SBP_bac_3
k59_1173863_1	572480.Arnit_0158	2.97e-12	65.5	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMM8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1173863_2	572480.Arnit_0157	9.32e-30	106.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_1173863_3	572480.Arnit_0156	5.63e-21	90.9	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2YMCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iIT341.HP0476	tRNA-synt_1c
k59_270208_1	929556.Solca_3454	1.43e-81	247.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1219272_1	1121121.KB894298_gene4035	4.1e-17	85.9	COG0243@1|root,COG0243@2|Bacteria,1UJ0U@1239|Firmicutes,4IUIP@91061|Bacilli,277MX@186822|Paenibacillaceae	91061|Bacilli	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1683270_1	1122619.KB892301_gene2599	4.67e-42	148.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,3T55W@506|Alcaligenaceae	28216|Betaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_156663_1	1415780.JPOG01000001_gene629	4.09e-11	69.7	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1X43X@135614|Xanthomonadales	135614|Xanthomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_42531_1	926559.JoomaDRAFT_2575	2.9e-59	205.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
k59_1345966_1	929558.SMGD1_0880	1.01e-68	211.0	COG1815@1|root,COG1815@2|Bacteria,1PSBA@1224|Proteobacteria,42VSQ@68525|delta/epsilon subdivisions,2YSYA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k59_42541_2	411154.GFO_0099	5.39e-17	76.3	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1HYRH@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_1173907_1	1123326.JFBL01000001_gene1475	1.69e-83	258.0	COG1284@1|root,COG1284@2|Bacteria,1R3UZ@1224|Proteobacteria,42P9H@68525|delta/epsilon subdivisions,2YR79@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_1173907_2	1442598.JABW01000025_gene1146	1.15e-90	278.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2YNV0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_1345976_1	326298.Suden_0780	6.63e-133	402.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_1117228_1	391598.FBBAL38_04610	6.55e-10	61.6	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1117228_2	1313301.AUGC01000005_gene278	1.44e-39	140.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_42554_1	768704.Desmer_3595	1.69e-29	115.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,262KW@186807|Peptococcaceae	186801|Clostridia	G	Periplasmic binding protein-like domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_1740025_1	411154.GFO_0480	1.47e-22	87.8	2ENQB@1|root,33GBM@2|Bacteria,4NYA3@976|Bacteroidetes,1I6RR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1740025_2	411154.GFO_0481	2.89e-53	172.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_327799_1	411154.GFO_2708	9.39e-60	190.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
k59_1173951_1	1172190.M947_06980	2.47e-13	69.3	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_1173951_2	929558.SMGD1_0397	2.33e-30	108.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_1173951_3	1172190.M947_06970	7.7e-95	281.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2YMCQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_215048_1	1121931.AUHG01000010_gene796	1.99e-82	267.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1000057_1	1237149.C900_00612	3.13e-77	244.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,47MRQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
k59_1346045_1	323850.Shew_2663	7.6e-86	272.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,2QAXK@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1219393_1	929558.SMGD1_1754	2.37e-22	89.7	COG1399@1|root,COG1399@2|Bacteria,1Q1I8@1224|Proteobacteria,42TRP@68525|delta/epsilon subdivisions,2YQ23@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_1219393_2	1172190.M947_04370	6.52e-29	103.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Z@1224|Proteobacteria,42VA5@68525|delta/epsilon subdivisions,2YQ6U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_1219393_3	929558.SMGD1_1756	2.43e-07	50.8	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_102304_1	1469557.JSWF01000012_gene1223	1.97e-25	104.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HZAB@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_102304_2	1267533.KB906735_gene5027	5.94e-17	80.1	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
k59_497165_1	323850.Shew_1852	9.27e-102	322.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QA13@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrF	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_440198_1	1565129.JSFF01000019_gene1642	2.31e-13	70.1	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,2QAI7@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_440198_2	1565129.JSFF01000019_gene1641	6.17e-21	86.3	2BPGX@1|root,32I9A@2|Bacteria,1QERV@1224|Proteobacteria,1TBKZ@1236|Gammaproteobacteria,2QCYY@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2986)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2986
k59_1000121_1	709032.Sulku_1658	1.14e-37	147.0	COG2199@1|root,COG2202@1|root,COG3221@1|root,COG3290@1|root,COG2202@2|Bacteria,COG3221@2|Bacteria,COG3290@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42RY7@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,dCache_1
k59_1219436_1	1380600.AUYN01000007_gene3226	3.33e-118	344.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1HY55@117743|Flavobacteriia	976|Bacteroidetes	G	sugar kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_1219436_2	746697.Aeqsu_2123	0.000542	42.4	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1287303_1	1442598.JABW01000027_gene915	3.42e-16	84.3	COG2604@1|root,COG2604@2|Bacteria,1Q4PY@1224|Proteobacteria,42X2A@68525|delta/epsilon subdivisions,2YTNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_1568831_1	572480.Arnit_2295	7.4e-123	360.0	COG0479@1|root,COG2048@1|root,COG0479@2|Bacteria,COG2048@2|Bacteria,1QE4T@1224|Proteobacteria,42QE6@68525|delta/epsilon subdivisions,2YM7P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1568831_2	1565314.OA34_09840	2.03e-15	75.1	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_270377_1	1123514.KB905899_gene1562	2.68e-139	400.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,45ZSC@72273|Thiotrichales	72273|Thiotrichales	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_607546_1	1123514.KB905899_gene1892	6.78e-94	289.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,460GW@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_215155_1	1172190.M947_04800	2.27e-123	362.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2YRIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_215155_2	1123326.JFBL01000005_gene1112	3.53e-13	68.9	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_497244_1	1123517.JOMR01000001_gene1311	2.41e-85	271.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,45ZVA@72273|Thiotrichales	72273|Thiotrichales	GM	Polysaccharide biosynthesis protein	wbtA	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_1174082_1	1123277.KB893186_gene5394	1.74e-28	111.0	2A8RJ@1|root,30XU9@2|Bacteria,4PBDC@976|Bacteroidetes,47VPI@768503|Cytophagia	976|Bacteroidetes	S	KilA-N	-	-	-	-	-	-	-	-	-	-	-	-	KilA-N
k59_42692_1	983544.Lacal_1611	7.45e-36	128.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia	976|Bacteroidetes	S	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_42692_2	1137281.D778_01008	8.71e-97	283.0	COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes,1HXIB@117743|Flavobacteriia	976|Bacteroidetes	L	Phenylacetate-CoA oxygenase	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
k59_42692_3	1046627.BZARG_1568	4.61e-51	168.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_1059939_1	411154.GFO_2105	8.19e-28	107.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1HX1Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_1059939_2	1353276.JADR01000002_gene2264	1.91e-15	74.7	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1HYTR@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_778714_1	1121931.AUHG01000015_gene1152	1.17e-86	266.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,1HWV9@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_1514799_1	1185766.DL1_01010	3.11e-109	339.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2XMFI@285107|Thioclava	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_1219501_1	945713.IALB_2626	2.1e-06	49.7	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
k59_1219501_2	109760.SPPG_08631T0	2.82e-35	131.0	COG0604@1|root,KOG1198@2759|Eukaryota,38ENU@33154|Opisthokonta,3PAY9@4751|Fungi	4751|Fungi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2
k59_1797248_1	1121931.AUHG01000010_gene616	6.98e-178	505.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_382912_1	1121931.AUHG01000012_gene2876	3.54e-168	482.0	COG3637@1|root,COG3637@2|Bacteria,4PMC3@976|Bacteroidetes,1IJRA@117743|Flavobacteriia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_270422_1	997884.HMPREF1068_02375	1.33e-38	136.0	COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,2G2NP@200643|Bacteroidia,4AMWH@815|Bacteroidaceae	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_270422_2	1270193.JARP01000006_gene1795	2.58e-124	367.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia,2NSA5@237|Flavobacterium	976|Bacteroidetes	G	transporter	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
k59_1740247_1	572480.Arnit_1916	3.01e-35	124.0	COG2834@1|root,COG2834@2|Bacteria,1PQ15@1224|Proteobacteria,42WEH@68525|delta/epsilon subdivisions,2YPW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_1740247_2	944547.ABLL_1395	7.71e-27	109.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1194754_1	1189620.AJXL01000041_gene577	3.79e-84	276.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2NUYY@237|Flavobacterium	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,MAM,PepSY,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,fn3
k59_181941_1	1137281.D778_01198	5.85e-137	397.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1HZGV@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1311810_1	519989.ECTPHS_06952	3.82e-46	167.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1536386_1	641526.ADIWIN_1914	1.2e-37	129.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,1HYJF@117743|Flavobacteriia	976|Bacteroidetes	F	COG1864 DNA RNA endonuclease G, NUC1	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
k59_1536386_2	504487.JCM19302_1849	6.99e-69	215.0	COG1215@1|root,COG1215@2|Bacteria,4NFXI@976|Bacteroidetes,1HXPW@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1650277_1	1121931.AUHG01000015_gene1207	1.43e-203	569.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1HY1B@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
k59_970681_1	688270.Celal_1921	1.31e-77	235.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1I17W@117743|Flavobacteriia,1F961@104264|Cellulophaga	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_970681_2	1178825.ALIH01000001_gene2417	1.22e-66	213.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1I0Q4@117743|Flavobacteriia	976|Bacteroidetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
k59_1254116_2	1165841.SULAR_07835	1.92e-30	115.0	2F58Z@1|root,33XV7@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k59_633554_1	572480.Arnit_0665	1.36e-100	296.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1140957_1	709032.Sulku_1627	5.08e-91	280.0	COG0642@1|root,COG4753@1|root,COG2205@2|Bacteria,COG4753@2|Bacteria,1QXMY@1224|Proteobacteria,42W3X@68525|delta/epsilon subdivisions,2YR5Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_407498_1	1168289.AJKI01000025_gene1452	5.24e-52	186.0	28HY3@1|root,2Z83I@2|Bacteria,4NHFN@976|Bacteroidetes,2FX5V@200643|Bacteroidia,3XJV5@558415|Marinilabiliaceae	976|Bacteroidetes	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_294437_1	1392490.JHZX01000001_gene865	1.74e-71	240.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_1480630_1	1469557.JSWF01000044_gene620	3.39e-69	214.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,1HX0G@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1480630_2	1392490.JHZX01000001_gene2342	5.03e-21	92.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
k59_1366672_1	317025.Tcr_0521	1.12e-179	513.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,45ZUN@72273|Thiotrichales	72273|Thiotrichales	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
k59_1650312_1	1353276.JADR01000011_gene1543	5.84e-90	290.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mexF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1028898_2	1046627.BZARG_1643	1.08e-30	118.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1594222_1	316274.Haur_1218	2.92e-23	106.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
k59_11541_1	1380600.AUYN01000003_gene148	1.18e-101	297.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1HY9T@117743|Flavobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_11541_2	1380600.AUYN01000003_gene150	1.66e-63	196.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,1I2XU@117743|Flavobacteriia	976|Bacteroidetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k59_11541_3	1123037.AUDE01000027_gene2097	3.17e-50	178.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_1366683_1	572480.Arnit_0388	5.32e-110	342.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,TarH,dCache_2,sCache_2
k59_633608_1	1123514.KB905899_gene1800	6.7e-53	177.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_633608_2	90814.KL370891_gene253	2.07e-54	173.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,460T4@72273|Thiotrichales	72273|Thiotrichales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_1311882_1	929558.SMGD1_1883	1.2e-61	207.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_1594243_1	1380600.AUYN01000009_gene1556	5.35e-162	464.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1423836_1	865937.Gilli_0767	1.58e-34	123.0	2B7X4@1|root,32143@2|Bacteria,4NNUI@976|Bacteroidetes,1I2MC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_1423836_2	1380600.AUYN01000009_gene2092	1.09e-62	201.0	COG0451@1|root,COG0451@2|Bacteria,4NJ2M@976|Bacteroidetes,1HYEW@117743|Flavobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_915481_1	1105110.MC5_01720	6.69e-38	145.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,47EU1@766|Rickettsiales	766|Rickettsiales	C	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
k59_407546_1	1178825.ALIH01000001_gene2419	3.92e-245	714.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_915491_1	1172190.M947_10230	2.68e-145	425.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2YR9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_1763473_1	1123518.ARWI01000001_gene1579	3.04e-118	347.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S0A2@1236|Gammaproteobacteria,4635C@72273|Thiotrichales	72273|Thiotrichales	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_1763473_2	1123518.ARWI01000001_gene1578	4.17e-203	571.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,45ZTH@72273|Thiotrichales	72273|Thiotrichales	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k59_294501_1	760154.Sulba_1005	9.21e-203	595.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02030,ko:K07679	ko02020,ko05133,map02020,map05133	M00236,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
k59_350312_1	1121931.AUHG01000011_gene1939	1.57e-104	324.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1HZ6R@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor for Fe3 -dicitrate	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_124710_1	1123037.AUDE01000028_gene2968	2.62e-35	127.0	2CEYI@1|root,33P74@2|Bacteria,4NZG6@976|Bacteroidetes,1I6WG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124710_2	641526.ADIWIN_1658	1.19e-13	68.9	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
k59_1311924_1	1137281.D778_00107	1.93e-85	264.0	COG0247@1|root,COG0247@2|Bacteria,4PM9R@976|Bacteroidetes,1IJNY@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
k59_238577_1	317025.Tcr_1692	7.12e-105	322.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,45ZQY@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_1706804_1	592316.Pat9b_2114	3.83e-08	62.4	COG1511@1|root,COG1511@2|Bacteria,1QWV3@1224|Proteobacteria,1T4UM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1480719_1	1123514.KB905899_gene825	6.68e-31	132.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9
k59_1706808_1	1123518.ARWI01000001_gene98	7.79e-10	58.5	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1S6AG@1236|Gammaproteobacteria,462B4@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
k59_1706808_2	1123518.ARWI01000001_gene99	6.91e-39	139.0	28NXH@1|root,2ZBV3@2|Bacteria,1RDDP@1224|Proteobacteria,1S4JV@1236|Gammaproteobacteria,4610U@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1423871_1	90814.KL370891_gene1831	7.33e-142	410.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,461G1@72273|Thiotrichales	72273|Thiotrichales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1423871_2	1123514.KB905903_gene397	1.08e-155	449.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,4606N@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4478)	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k59_407600_1	1121931.AUHG01000017_gene1467	1.05e-155	455.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_238608_1	203122.Sde_0381	3.02e-61	201.0	COG3868@1|root,COG3868@2|Bacteria,1QYF8@1224|Proteobacteria,1S2AU@1236|Gammaproteobacteria,46D29@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Stealth protein CR1, conserved region 1	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2
k59_1650432_1	28229.ND2E_4116	4.57e-68	230.0	28IHV@1|root,2Z8J1@2|Bacteria,1PYRU@1224|Proteobacteria,1RXQJ@1236|Gammaproteobacteria,2Q7HJ@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Lyase, N terminal	Z012_00015	-	4.2.2.20,4.2.2.21	ko:K08961	-	-	-	-	ko00000,ko01000	-	-	-	Lyase_8,Lyase_8_C,Lyase_N,Lyase_catalyt
k59_238616_1	90814.KL370891_gene1762	3.1e-29	112.0	COG1639@1|root,COG1639@2|Bacteria,1RFEZ@1224|Proteobacteria	1224|Proteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_803283_1	1121931.AUHG01000011_gene1745	2.59e-24	97.1	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1HXD3@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_803283_2	411154.GFO_2776	8.11e-91	267.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_1084406_1	1380600.AUYN01000009_gene1087	4.64e-33	125.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
k59_1084406_2	1178825.ALIH01000007_gene1668	1.23e-63	201.0	28KSE@1|root,2ZA9S@2|Bacteria,4NKV8@976|Bacteroidetes,1I1N7@117743|Flavobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
k59_1084412_1	323850.Shew_1343	1.08e-112	330.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,2Q99N@267890|Shewanellaceae	1236|Gammaproteobacteria	T	response regulator receiver	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1650452_1	1123518.ARWI01000001_gene1468	1.77e-138	402.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,45ZN6@72273|Thiotrichales	72273|Thiotrichales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_690733_1	1178825.ALIH01000002_gene1083	5.88e-31	116.0	2DBMN@1|root,2Z9ZK@2|Bacteria,4NHPK@976|Bacteroidetes,1I2GU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_690733_2	1178825.ALIH01000002_gene1084	3.31e-140	396.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_690733_3	746697.Aeqsu_2964	1.49e-83	272.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N
k59_1194896_1	1123518.ARWI01000001_gene2244	1.08e-18	84.7	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,4604I@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_1194896_2	90814.KL370891_gene1419	4.13e-110	327.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_407634_1	411154.GFO_2118	4.15e-98	291.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,1I1SW@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
k59_407634_2	411154.GFO_2117	1.62e-43	146.0	COG2197@1|root,COG2197@2|Bacteria,4NN4D@976|Bacteroidetes,1I1NU@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_1029029_2	572480.Arnit_0676	1.53e-142	404.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1029029_3	572480.Arnit_0677	2.13e-64	208.0	COG0642@1|root,COG0642@2|Bacteria,1Q01G@1224|Proteobacteria,42RFV@68525|delta/epsilon subdivisions,2YPCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_1254308_1	675812.VHA_001824	1.6e-55	201.0	COG0683@1|root,COG1638@1|root,COG0683@2|Bacteria,COG1638@2|Bacteria,1MX94@1224|Proteobacteria,1RXJU@1236|Gammaproteobacteria,1XXB3@135623|Vibrionales	135623|Vibrionales	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	DctP,Peripla_BP_6
k59_182161_1	1172190.M947_02855	1.26e-108	318.0	COG0647@1|root,COG0647@2|Bacteria,1PYVR@1224|Proteobacteria,42NA1@68525|delta/epsilon subdivisions,2YMK0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	HAD-superfamily hydrolase, subfamily IIA	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
k59_407648_1	1121931.AUHG01000010_gene652	6.32e-69	212.0	COG2323@1|root,COG2323@2|Bacteria,4NR3N@976|Bacteroidetes,1I1DT@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
k59_407648_2	1121931.AUHG01000010_gene654	9.89e-62	193.0	2E527@1|root,32ZVF@2|Bacteria,4NV2Q@976|Bacteroidetes,1I57N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1480822_1	1123514.KB905899_gene1893	5.39e-35	123.0	2FIFI@1|root,34A7R@2|Bacteria,1P365@1224|Proteobacteria,1SS4R@1236|Gammaproteobacteria,4631F@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1480822_2	1123514.KB905899_gene1892	9.72e-42	147.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,460GW@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_1480828_1	411154.GFO_1540	1.67e-30	117.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,1HZQ1@117743|Flavobacteriia	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
k59_1480828_2	411154.GFO_1539	7.85e-60	197.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
k59_1255942_2	1380600.AUYN01000007_gene3410	4.2e-212	596.0	COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,1HXUZ@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1255942_3	1178825.ALIH01000003_gene2013	1.58e-57	182.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1HYRH@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_1368337_1	1178825.ALIH01000002_gene1014	1.01e-53	177.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_1368337_2	1046627.BZARG_103	1.01e-120	350.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1HXRT@117743|Flavobacteriia	976|Bacteroidetes	P	membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
k59_466101_1	90814.KL370891_gene515	3.05e-96	292.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,460BB@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_466101_2	1123518.ARWI01000001_gene804	6.56e-85	254.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,4606Y@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_1313715_1	411154.GFO_0219	1.08e-11	64.7	COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,1HWSM@117743|Flavobacteriia	976|Bacteroidetes	I	Long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1313715_2	1121931.AUHG01000010_gene872	1.67e-61	204.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1HY1A@117743|Flavobacteriia	976|Bacteroidetes	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
k59_917118_1	279714.FuraDRAFT_0669	1.28e-102	327.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2VI52@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k59_635462_1	572480.Arnit_1958	4.98e-117	339.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_971963_1	768671.ThimaDRAFT_4426	9.92e-148	430.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1538111_1	688270.Celal_3128	7.88e-97	286.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,1HWQ3@117743|Flavobacteriia,1F8KP@104264|Cellulophaga	976|Bacteroidetes	M	COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis	wcgN	-	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
k59_1538111_2	1380600.AUYN01000001_gene2294	6.43e-166	477.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,1HXBG@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
k59_296272_1	867900.Celly_2793	5.94e-133	384.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1HWKK@117743|Flavobacteriia,1F7TP@104264|Cellulophaga	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1495324_2	1122176.KB903565_gene3264	1.86e-88	266.0	28PQP@1|root,2ZCCM@2|Bacteria,4NSQ2@976|Bacteroidetes,1IZYZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
k59_421633_1	411154.GFO_0388	4.88e-100	295.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_1664579_1	1380600.AUYN01000007_gene3174	6.75e-126	365.0	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_364043_1	391603.FBALC1_11912	3.92e-121	368.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_364043_2	1380600.AUYN01000009_gene1577	2.5e-82	246.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,1I24N@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_364043_3	1484460.JSWG01000015_gene948	9.45e-36	126.0	2DQ1A@1|root,32UNA@2|Bacteria,4NT2M@976|Bacteroidetes,1I4EA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
k59_759678_1	1157490.EL26_01700	1.99e-52	178.0	COG3948@1|root,COG3948@2|Bacteria,1U044@1239|Firmicutes,4HCD5@91061|Bacilli	91061|Bacilli	S	Baseplate J protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_1098233_1	1123517.JOMR01000001_gene929	1.8e-07	59.3	COG3064@1|root,COG3064@2|Bacteria,1PGR7@1224|Proteobacteria,1RUMZ@1236|Gammaproteobacteria,46273@72273|Thiotrichales	72273|Thiotrichales	M	TolA C-terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
k59_138380_1	1380384.JADN01000004_gene1898	2.85e-18	81.3	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1HYYB@117743|Flavobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k59_138380_2	504487.JCM19302_3773	1.6e-175	508.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,1HYEB@117743|Flavobacteriia	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,DUF4301
k59_1550144_1	1123518.ARWI01000001_gene1127	5.1e-25	98.2	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,461V2@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_1550144_2	1123518.ARWI01000001_gene1126	4.97e-34	127.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1S8CZ@1236|Gammaproteobacteria,46317@72273|Thiotrichales	72273|Thiotrichales	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
k59_981198_1	572480.Arnit_2757	5.04e-96	301.0	COG2984@1|root,COG5000@1|root,COG2984@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43D06@68525|delta/epsilon subdivisions,2YRHW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,PAS_9
k59_421651_1	1380600.AUYN01000001_gene2627	2.19e-100	303.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia	976|Bacteroidetes	G	Transporter	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
k59_705929_1	742725.HMPREF9450_02019	6.36e-119	374.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22U9I@171550|Rikenellaceae	976|Bacteroidetes	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1495361_1	1178825.ALIH01000007_gene1678	5.45e-97	291.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1HYTR@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1495364_2	285514.JNWO01000019_gene7718	1.12e-37	131.0	COG3607@1|root,COG3607@2|Bacteria,2IKVS@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1550164_1	317025.Tcr_0811	1.25e-52	170.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,460FZ@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_1550164_2	1123518.ARWI01000001_gene2248	1.37e-136	404.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,45ZVM@72273|Thiotrichales	72273|Thiotrichales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1098277_1	1506583.JQJY01000002_gene1461	8.27e-24	105.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HYMP@117743|Flavobacteriia,2NUWQ@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1721032_1	563040.Saut_0649	3.11e-60	194.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,42ND2@68525|delta/epsilon subdivisions,2YMQ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_2
k59_1721032_2	563040.Saut_0650	6.04e-26	101.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42SSI@68525|delta/epsilon subdivisions,2YPE6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_705966_1	326298.Suden_0456	1.01e-101	299.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2YNZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_590742_1	1355368.JART01000019_gene1113	8.28e-71	228.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Y8P@68525|delta/epsilon subdivisions,2YR3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c
k59_83195_1	563040.Saut_0510	3.86e-115	338.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2YMJU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_759739_2	572547.Amico_1103	9.22e-28	112.0	COG4385@1|root,COG4385@2|Bacteria,3TBRZ@508458|Synergistetes	508458|Synergistetes	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
k59_759739_3	97138.C820_00597	2.26e-14	80.1	COG5301@1|root,COG5301@2|Bacteria,1VB8Z@1239|Firmicutes,24NQY@186801|Clostridia,36MMI@31979|Clostridiaceae	186801|Clostridia	UW	Phage tail-collar fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3751,Peptidase_S74
k59_534571_1	1150600.ADIARSV_3255	5.29e-99	309.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,1IQ0C@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
k59_534571_2	1123008.KB905708_gene989	6.79e-104	306.0	2E1FR@1|root,32WUC@2|Bacteria,4NTFG@976|Bacteroidetes,2G2H8@200643|Bacteroidia,22YRJ@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3823)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3823
k59_534571_3	1123008.KB905708_gene988	1.28e-259	733.0	COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,2FMZF@200643|Bacteroidia,22X0A@171551|Porphyromonadaceae	976|Bacteroidetes	F	Pfam:SusD	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
k59_534571_4	1123008.KB905708_gene987	0.0	1366.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FWW6@200643|Bacteroidia,22VWN@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_534571_5	143224.JQMD01000002_gene1795	5.35e-109	328.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1HWRF@117743|Flavobacteriia	976|Bacteroidetes	PT	COG3712 Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_534571_7	985255.APHJ01000018_gene3071	8.45e-40	140.0	COG1595@1|root,COG1595@2|Bacteria,4NRYN@976|Bacteroidetes,1I2XK@117743|Flavobacteriia,2P7RF@244698|Gillisia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_534571_9	1408473.JHXO01000007_gene924	2.64e-29	110.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k59_534571_10	1306990.BARG01000053_gene6410	4.28e-31	122.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_534571_11	313606.M23134_02257	7.55e-24	96.3	2E2ZW@1|root,32Y0H@2|Bacteria,4P8E2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1098307_1	90813.JQMT01000001_gene1011	8.96e-65	206.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,460DX@72273|Thiotrichales	72273|Thiotrichales	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_1098307_2	1123518.ARWI01000001_gene216	1.62e-112	335.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,460YG@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_1380615_1	224308.BSU12570	8.9e-06	53.5	COG3728@1|root,COG5484@1|root,COG3728@2|Bacteria,COG5484@2|Bacteria,1V8HJ@1239|Firmicutes,4HJ4Z@91061|Bacilli,1ZEK7@1386|Bacillus	91061|Bacilli	L	phage terminase small subunit	xtmA	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Ftsk_gamma,Phage_terminase,Terminase_2
k59_1380615_2	104623.Ser39006_04165	5.1e-48	168.0	COG1783@1|root,COG1783@2|Bacteria,1R6J1@1224|Proteobacteria,1RS5V@1236|Gammaproteobacteria,40262@613|Serratia	1236|Gammaproteobacteria	S	Mu-like prophage FluMu protein gp28	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	-
k59_83214_1	1123228.AUIH01000002_gene1544	2.13e-66	217.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XHNY@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1268483_1	1123514.KB905899_gene1955	2.7e-149	445.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1495450_1	1380600.AUYN01000009_gene1967	8.06e-79	249.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1HZGE@117743|Flavobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
k59_1495450_2	1121912.AUHD01000001_gene2549	1.54e-37	129.0	COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,1I3VH@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
k59_1495450_3	504487.JCM19302_628	2.59e-102	300.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1I1UF@117743|Flavobacteriia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1495450_4	1353276.JADR01000009_gene1816	3.9e-54	177.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,1HZWV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_818163_1	1123057.P872_11475	3.06e-142	408.0	28K33@1|root,2Z9SC@2|Bacteria,4NISC@976|Bacteroidetes,47NA0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_981299_1	1123514.KB905899_gene879	1.31e-62	208.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,1S535@1236|Gammaproteobacteria,4635K@72273|Thiotrichales	72273|Thiotrichales	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_981299_2	1123518.ARWI01000001_gene2374	2.32e-46	157.0	COG0845@1|root,COG0845@2|Bacteria,1R9JJ@1224|Proteobacteria,1S1HQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18901	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_981299_3	1123514.KB905899_gene881	1.26e-56	176.0	2FE1C@1|root,3461J@2|Bacteria,1P2W3@1224|Proteobacteria,1ST1N@1236|Gammaproteobacteria,4631V@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_981299_5	1123514.KB905899_gene883	8.31e-93	279.0	COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,1T2D2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH
k59_706052_1	563040.Saut_1913	2.68e-106	315.0	2AIIS@1|root,3190V@2|Bacteria,1Q1CZ@1224|Proteobacteria,42TB4@68525|delta/epsilon subdivisions,2YPN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_308940_2	402626.Rpic_0370	1.71e-54	173.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1K791@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k59_1326804_1	56107.Cylst_4978	4.87e-23	100.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1GQ5I@1117|Cyanobacteria,1HN0Q@1161|Nostocales	1117|Cyanobacteria	T	Diguanylate cyclase	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CBS,EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_1326804_2	1390370.O203_03680	4.65e-62	211.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1YJ3H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K11914	-	-	-	-	ko00000,ko02044,ko03000	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_364190_2	929558.SMGD1_1214	2.97e-78	241.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2YMMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_818178_1	1137281.D778_02049	3.84e-05	44.3	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,1I2TS@117743|Flavobacteriia	976|Bacteroidetes	J	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_818178_2	1197477.IA57_03810	2.73e-49	159.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
k59_818178_3	1380600.AUYN01000006_gene730	9.7e-152	430.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1HXMG@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_818178_4	1137281.D778_02045	3.1e-175	503.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_1495479_1	1172190.M947_02520	5.5e-100	296.0	COG0388@1|root,COG0388@2|Bacteria,1PZZZ@1224|Proteobacteria,42REP@68525|delta/epsilon subdivisions,2YP77@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_1382631_2	216432.CA2559_00290	1.99e-199	555.0	COG3577@1|root,COG3577@2|Bacteria,4NSCQ@976|Bacteroidetes,1I6DD@117743|Flavobacteriia	976|Bacteroidetes	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
k59_1552285_1	945713.IALB_0772	5.05e-37	137.0	COG0056@1|root,COG0056@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1552285_2	96561.Dole_0602	9.98e-12	65.9	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2MIR3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1780461_1	504487.JCM19302_1379	4.16e-213	660.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1780469_1	1123518.ARWI01000001_gene2164	1.64e-68	222.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1780469_2	1168067.JAGP01000001_gene1488	2.89e-23	93.2	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,460FA@72273|Thiotrichales	72273|Thiotrichales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k59_931201_1	572480.Arnit_0915	1.01e-69	224.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2YMZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_875477_1	1189619.pgond44_11311	5.85e-204	581.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia,4C2NY@83612|Psychroflexus	976|Bacteroidetes	CP	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_875477_2	1189620.AJXL01000051_gene1216	4.47e-110	343.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,1I0SZ@117743|Flavobacteriia,2NVHN@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_1044960_1	1123518.ARWI01000001_gene2001	7.74e-59	193.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,4607E@72273|Thiotrichales	72273|Thiotrichales	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1044960_2	1123518.ARWI01000001_gene2000	8.46e-50	166.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,460CS@72273|Thiotrichales	72273|Thiotrichales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1100450_1	1122599.AUGR01000028_gene1441	3.25e-20	89.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1XIP9@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1100450_2	1278309.KB907109_gene3261	2.68e-67	209.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XJBB@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_536682_1	1121931.AUHG01000010_gene718	4.35e-116	343.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia	976|Bacteroidetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_27084_1	926562.Oweho_3508	6.32e-40	146.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2PAW1@246874|Cryomorphaceae	976|Bacteroidetes	CO	Thioredoxin-like	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
k59_366321_1	616991.JPOO01000001_gene4434	1.32e-112	333.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,1I1BA@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_366323_1	1380600.AUYN01000009_gene1770	8.54e-180	521.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_140596_1	313596.RB2501_01415	4.09e-09	62.8	COG1061@1|root,COG2093@1|root,COG1061@2|Bacteria,COG2093@2|Bacteria,4NECV@976|Bacteroidetes,1HXAD@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_140596_4	1336237.JAEE01000001_gene2119	1.29e-22	101.0	2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,1RQE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease VIII	-	-	-	ko:K10906	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF3799
k59_140596_6	649831.L083_6016	1.45e-30	125.0	28KIJ@1|root,2ZA3S@2|Bacteria,2GP60@201174|Actinobacteria,4DIRE@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1281826_1	1121918.ARWE01000001_gene394	6.33e-05	43.9	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,43T9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_7,Oxidored_q6
k59_1281826_2	1232410.KI421427_gene1295	5.44e-71	228.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,43SVB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
k59_322449_1	1196835.A458_09855	3.2e-20	93.6	COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,1Z1B0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	MP	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	OmpA,PBP_like_2
k59_602453_1	1232410.KI421424_gene1752	1.99e-85	276.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,43S51@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
k59_151856_1	243231.GSU1269	3.63e-66	230.0	COG1470@1|root,COG5276@1|root,COG1470@2|Bacteria,COG5276@2|Bacteria,1NTT8@1224|Proteobacteria,42ZD4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
k59_940645_1	411154.GFO_1691	5.03e-40	141.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1HWKD@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM aldo keto reductase	gpr	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
k59_940645_2	1229487.AMYW01000002_gene1512	1.72e-39	140.0	COG0604@1|root,COG0604@2|Bacteria,4NPBM@976|Bacteroidetes,1I9K8@117743|Flavobacteriia,2NU8D@237|Flavobacterium	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_322492_1	1121931.AUHG01000018_gene1373	2.29e-58	188.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_322492_2	1249975.JQLP01000005_gene1218	6.97e-47	156.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,1I1XP@117743|Flavobacteriia,2P7KM@244698|Gillisia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_940653_1	1131812.JQMS01000001_gene323	1.37e-25	105.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1I4ES@117743|Flavobacteriia,2NXTG@237|Flavobacterium	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
k59_96729_1	367737.Abu_1643	8.69e-82	251.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,42KZB@68525|delta/epsilon subdivisions,2YN63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_1394254_1	411154.GFO_3386	4.61e-206	578.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_209683_1	1317122.ATO12_08620	2.72e-60	199.0	COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,1HXMY@117743|Flavobacteriia,2YGSP@290174|Aquimarina	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1168603_1	1123228.AUIH01000004_gene1040	4.08e-95	302.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XIHW@135619|Oceanospirillales	135619|Oceanospirillales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
k59_602507_1	572480.Arnit_2409	6.12e-98	297.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2YMTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_209699_1	1123518.ARWI01000001_gene1771	7.91e-50	164.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,460D0@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_209699_2	1123514.KB905903_gene369	3.41e-40	135.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	ysmA	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
k59_1678080_1	94624.Bpet3017	2.02e-76	246.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,3T1SX@506|Alcaligenaceae	28216|Betaproteobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_1054462_2	1150621.SMUL_0509	4.42e-77	244.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2YMNX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1214211_1	411154.GFO_3071	6.7e-186	533.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_1281937_1	935866.JAER01000009_gene791	8.72e-35	133.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DP9T@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
k59_96815_1	1121931.AUHG01000011_gene1728	7.03e-117	350.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_265864_1	1121931.AUHG01000010_gene347	1.2e-61	194.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_265864_2	411154.GFO_3355	1.44e-51	168.0	28KJI@1|root,2ZA4I@2|Bacteria,4NFR7@976|Bacteroidetes,1I30H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1054501_1	1121931.AUHG01000010_gene277	8.26e-156	444.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1HX73@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_886856_1	1349785.BAUG01000022_gene1434	2.81e-23	95.9	COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_886856_2	616991.JPOO01000001_gene3950	1.35e-74	229.0	28HM7@1|root,2Z7VU@2|Bacteria,4NGV1@976|Bacteroidetes,1HXYU@117743|Flavobacteriia,23H68@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_773016_1	1178825.ALIH01000016_gene622	7.5e-97	291.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_773016_2	1380600.AUYN01000001_gene2265	4.11e-11	62.4	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1HWSR@117743|Flavobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_265883_2	643867.Ftrac_0450	3.66e-32	125.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47UF7@768503|Cytophagia	976|Bacteroidetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_1678163_1	326298.Suden_0534	2.54e-65	214.0	COG1538@1|root,COG1538@2|Bacteria,1R860@1224|Proteobacteria,42R4V@68525|delta/epsilon subdivisions,2YNVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1678172_1	90813.JQMT01000001_gene964	2.46e-80	240.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,460MU@72273|Thiotrichales	72273|Thiotrichales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_1678172_2	1123518.ARWI01000001_gene167	1.76e-74	228.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,46091@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_152036_1	313603.FB2170_14833	5e-72	242.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PG6S@252356|Maribacter	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_377384_1	1117315.AHCA01000007_gene3735	2.17e-41	153.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,2PZP9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
k59_491884_1	929558.SMGD1_0931	1.78e-145	420.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2YN43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_602610_1	1353529.M899_1161	3.16e-41	147.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,42Q1N@68525|delta/epsilon subdivisions,2MSN0@213481|Bdellovibrionales,2WK3A@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_773052_1	1123518.ARWI01000001_gene2117	7.05e-79	245.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales	72273|Thiotrichales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_773052_2	1123514.KB905899_gene535	2.14e-55	181.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,4613W@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k59_1791764_1	1278309.KB907100_gene2061	3.92e-97	292.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XH6E@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1622491_1	929558.SMGD1_1533	1.33e-171	486.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1054576_1	1121931.AUHG01000011_gene2227	8.35e-66	206.0	COG4733@1|root,COG4733@2|Bacteria,4NQRS@976|Bacteroidetes,1I3C0@117743|Flavobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1734521_1	1380600.AUYN01000009_gene1469	1.04e-60	196.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1734521_2	1353276.JADR01000010_gene1657	1.24e-26	102.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1I0RX@117743|Flavobacteriia	976|Bacteroidetes	M	serine threonine protein kinase	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
k59_377427_1	1123518.ARWI01000001_gene358	3.88e-104	310.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,45ZZZ@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_491926_1	1453501.JELR01000002_gene1322	3.48e-33	124.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
k59_1054582_1	425104.Ssed_0280	7.23e-32	117.0	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria,2QBRQ@267890|Shewanellaceae	1236|Gammaproteobacteria	NPTU	LTXXQ motif family protein	spy	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ
k59_1054582_2	425104.Ssed_0281	2.42e-18	82.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,2QAA2@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
k59_546508_1	367737.Abu_0631	1.04e-45	173.0	COG4191@1|root,COG4191@2|Bacteria,1PFGC@1224|Proteobacteria,42Z6H@68525|delta/epsilon subdivisions,2YRF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,PAS_9
k59_1340795_1	572480.Arnit_1656	2.87e-112	327.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2YMNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1112004_1	398579.Spea_0246	8.69e-129	372.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,2Q8QR@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF1260.b3384,iB21_1397.B21_03188,iBWG_1329.BWG_3075,iEC042_1314.EC042_3645,iECBD_1354.ECBD_0363,iECB_1328.ECB_03236,iECDH10B_1368.ECDH10B_3559,iECDH1ME8569_1439.ECDH1ME8569_3263,iECD_1391.ECD_03236,iECUMN_1333.ECUMN_3842,iECW_1372.ECW_m3639,iEKO11_1354.EKO11_0361,iEcDH1_1363.EcDH1_0329,iEcHS_1320.EcHS_A3580,iEcolC_1368.EcolC_0329,iJO1366.b3384,iLF82_1304.LF82_2316,iNRG857_1313.NRG857_16750,iPC815.YPO0157,iUMNK88_1353.UMNK88_4150,iWFL_1372.ECW_m3639,iY75_1357.Y75_RS20300	tRNA-synt_1b
k59_100553_4	555500.I215_03620	2.82e-08	55.8	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_998413_1	572480.Arnit_1646	6.42e-11	61.6	COG2866@1|root,COG2866@2|Bacteria,1PFUZ@1224|Proteobacteria,43AHH@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,P_proprotein,Peptidase_M14
k59_998413_2	572480.Arnit_1647	1.06e-64	212.0	COG0189@1|root,COG1555@1|root,COG0189@2|Bacteria,COG1555@2|Bacteria,1R8K6@1224|Proteobacteria,43A4Z@68525|delta/epsilon subdivisions,2YNII@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,HHH_5,RimK
k59_1567203_1	1250005.PHEL85_1898	3.13e-107	320.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes,1HYPJ@117743|Flavobacteriia	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1567203_2	1484460.JSWG01000006_gene2963	9.18e-104	310.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia	976|Bacteroidetes	V	transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_100578_1	425104.Ssed_2738	1.63e-75	238.0	COG0845@1|root,COG0845@2|Bacteria,1R78S@1224|Proteobacteria,1S0GJ@1236|Gammaproteobacteria,2QA9F@267890|Shewanellaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
k59_1285606_1	876044.IMCC3088_2504	9.04e-06	50.4	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_1285606_2	717773.Thicy_0462	9e-62	190.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,46133@72273|Thiotrichales	72273|Thiotrichales	J	Sigma 54 modulation protein	yhbH	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_1285606_3	1123514.KB905899_gene1614	1.6e-142	405.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,45ZYJ@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter, ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_1285606_4	1123514.KB905899_gene1613	3.24e-33	123.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,4615G@72273|Thiotrichales	72273|Thiotrichales	T	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,SH3_3
k59_1567239_1	983544.Lacal_0343	7.65e-133	391.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1HX0N@117743|Flavobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1567239_2	1408473.JHXO01000008_gene2840	1.71e-49	164.0	2DP52@1|root,330JK@2|Bacteria,4NUTX@976|Bacteroidetes,2FVVA@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_326224_1	1380600.AUYN01000007_gene3163	2.02e-208	595.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_1115623_1	1137281.D778_01253	2.01e-128	380.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Beta-lactamase2,DUF3471
k59_100620_1	498211.CJA_2072	9.21e-25	107.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1FG8F@10|Cellvibrio	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
k59_606111_1	123214.PERMA_1579	2.07e-55	188.0	COG2379@1|root,COG2379@2|Bacteria	2|Bacteria	G	hydroxypyruvate reductase	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k59_100630_1	323850.Shew_0479	3.28e-88	271.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,1RR5N@1236|Gammaproteobacteria,2QB95@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM HipA domain protein	hipA_1	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k59_606114_1	1380600.AUYN01000009_gene1542	4.35e-126	362.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1HXQW@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_606114_2	445961.IW15_09045	6.26e-35	120.0	COG3655@1|root,COG3655@2|Bacteria,4NUP7@976|Bacteroidetes,1I506@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
k59_606114_3	1123276.KB893269_gene4778	1.81e-81	244.0	293T3@1|root,2ZR8H@2|Bacteria,4NMK3@976|Bacteroidetes,47PZ7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
k59_549793_1	929558.SMGD1_0603	4.6e-47	154.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2YP0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1344355_1	504487.JCM19302_1871	4.37e-56	190.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1344355_2	1178825.ALIH01000008_gene793	1.25e-72	230.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_998526_1	362418.IW19_17410	6.92e-127	369.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1HXG5@117743|Flavobacteriia,2NTMT@237|Flavobacterium	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_326279_1	317025.Tcr_1354	4.52e-40	152.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	SPOR,YARHG
k59_326279_3	396588.Tgr7_1062	3.4e-34	122.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,1WYWP@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0225 family	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_1217774_1	616991.JPOO01000001_gene3332	1.72e-111	325.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1HYTE@117743|Flavobacteriia	976|Bacteroidetes	P	COG0569 K transport systems NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_1217774_2	616991.JPOO01000001_gene3331	1.9e-217	615.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1HY9Z@117743|Flavobacteriia	976|Bacteroidetes	P	potassium uptake protein, TrkH family	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1381364_2	1123514.KB905902_gene235	1.75e-90	298.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,460CJ@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_2,VWA_2
k59_364934_1	85643.Tmz1t_0606	7.12e-73	243.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,2KUFA@206389|Rhodocyclales	206389|Rhodocyclales	H	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_197114_1	1157490.EL26_15515	2.55e-09	61.6	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,279SH@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9
k59_1205493_1	484770.UFO1_0816	1.19e-51	174.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H79Z@909932|Negativicutes	909932|Negativicutes	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
k59_929899_1	1484460.JSWG01000005_gene2698	5.1e-69	233.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
k59_929899_2	1178825.ALIH01000007_gene1630	5.62e-164	463.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HZ5R@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_929899_3	1178825.ALIH01000007_gene1629	1.59e-31	110.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1I50J@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_929899_4	1178825.ALIH01000007_gene1627	4.94e-27	105.0	2BVTQ@1|root,2Z7J9@2|Bacteria,4NGSY@976|Bacteroidetes,1HWRX@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k59_139237_1	572480.Arnit_1346	2e-102	318.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
k59_1269288_1	387093.SUN_1661	2.23e-35	126.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2YMRF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1269288_2	929558.SMGD1_2232	8.51e-71	228.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2YM8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1721880_1	572480.Arnit_2380	7.12e-38	149.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria	2|Bacteria	T	Single Cache domain 2	-	-	2.7.13.3	ko:K03406,ko:K13040	ko02020,ko02030,map02020,map02030	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	EAL,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_2
k59_1550995_1	1122179.KB890469_gene599	1.81e-114	365.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1550995_2	1122179.KB890469_gene600	5.46e-126	386.0	COG0702@1|root,COG0702@2|Bacteria,4NH54@976|Bacteroidetes,1IQ59@117747|Sphingobacteriia	976|Bacteroidetes	GM	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1550995_3	1123008.KB905698_gene3475	3.77e-226	654.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,22WGY@171551|Porphyromonadaceae	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_254076_1	1380600.AUYN01000001_gene2671	0.0	916.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_1721882_2	317025.Tcr_1207	7.49e-48	156.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,46162@72273|Thiotrichales	72273|Thiotrichales	P	arsenate reductase	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_1099126_1	572480.Arnit_0145	4.94e-119	352.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_256810_2	983544.Lacal_2913	2.07e-59	184.0	COG3668@1|root,COG3668@2|Bacteria,4NQ43@976|Bacteroidetes,1I3IS@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the RelE toxin family	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_141826_1	1121931.AUHG01000011_gene2064	8.31e-134	380.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1HX8T@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_1440824_1	1380600.AUYN01000001_gene2671	5.09e-81	269.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_482214_1	1300345.LF41_794	4.23e-45	159.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Phage-tail_3,TIG
k59_651326_1	929558.SMGD1_0104	1.34e-213	605.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_651326_2	929558.SMGD1_0103	4.19e-20	88.6	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_86632_1	1121912.AUHD01000008_gene32	7.63e-260	719.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HWYG@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_86632_2	1122225.AULQ01000002_gene585	3.89e-110	318.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_86632_3	1123037.AUDE01000001_gene1856	2.95e-84	265.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1HXA7@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_709894_1	572480.Arnit_1083	8.09e-51	170.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2YMGD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_709894_2	572480.Arnit_1084	5.16e-89	266.0	COG0596@1|root,COG0596@2|Bacteria,1NH3R@1224|Proteobacteria,42R8Q@68525|delta/epsilon subdivisions,2YNWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_367612_1	1158345.JNLL01000001_gene725	2.43e-84	266.0	COG2223@1|root,COG2223@2|Bacteria,2G5HV@200783|Aquificae	200783|Aquificae	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1440843_2	335992.SAR11_0216	1.56e-29	121.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,4BPCP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1498948_1	944547.ABLL_2314	8.63e-113	365.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,SBP_bac_3
k59_1781836_1	326298.Suden_0877	3.14e-87	272.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_594080_1	317025.Tcr_2064	1.05e-72	239.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T239@1236|Gammaproteobacteria,461MW@72273|Thiotrichales	72273|Thiotrichales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1440853_1	1348657.M622_14590	8.43e-26	101.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,2KUN1@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_1440853_2	420662.Mpe_A2829	1.16e-43	152.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VH77@28216|Betaproteobacteria,1KJW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain	lldD	-	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
k59_1271947_1	1565129.JSFF01000014_gene385	1.24e-83	261.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,2QAFQ@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,STAS_2,Sulfate_transp
k59_1498971_1	395493.BegalDRAFT_0442	3.38e-62	216.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_28325_1	1380600.AUYN01000003_gene205	4.61e-61	194.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,1HXTK@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
k59_28325_2	1392490.JHZX01000001_gene2580	2.15e-24	102.0	28IMZ@1|root,2Z8NF@2|Bacteria,4NIZ8@976|Bacteroidetes,1I0D0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_763220_1	748247.AZKH_3121	7.01e-128	378.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VMKP@28216|Betaproteobacteria,2KV5U@206389|Rhodocyclales	206389|Rhodocyclales	H	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1440884_1	1172190.M947_10905	3.42e-26	100.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42RMF@68525|delta/epsilon subdivisions,2YPMK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_1440884_2	929558.SMGD1_0551	5.16e-69	212.0	2994D@1|root,2ZW7V@2|Bacteria,1Q2D1@1224|Proteobacteria,42VGB@68525|delta/epsilon subdivisions,2YQM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1330326_1	572480.Arnit_1823	4.01e-90	275.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1330326_2	572480.Arnit_1822	6.82e-136	396.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1271986_1	411154.GFO_2979	2.48e-46	160.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,1HWMR@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_1668062_1	1250278.JQNQ01000001_gene876	1.43e-61	212.0	COG0841@1|root,COG0841@2|Bacteria,4NE3H@976|Bacteroidetes,1HZ8H@117743|Flavobacteriia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1330328_1	177439.DP0944	2.73e-36	126.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MMGF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_651409_1	317025.Tcr_1281	1.66e-74	229.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_651409_2	1123514.KB905899_gene932	1.27e-79	248.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,460ZX@72273|Thiotrichales	72273|Thiotrichales	I	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_1271992_1	1172190.M947_00615	1.56e-90	277.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_312354_1	1121931.AUHG01000010_gene320	8.26e-31	120.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_312354_2	1121931.AUHG01000010_gene321	1.21e-82	256.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1I0Z8@117743|Flavobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,MarR,ROK
k59_821725_1	675812.VHA_001944	8.48e-22	87.8	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1XXC1@135623|Vibrionales	135623|Vibrionales	C	Iron-sulfur cluster insertion protein ErpA	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k59_821725_2	90813.JQMT01000001_gene258	3.71e-118	347.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,4609M@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1207118_1	1123514.KB905899_gene873	2.22e-27	105.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,460KB@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_1207118_2	90814.KL370891_gene1352	4e-85	260.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4600E@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_651429_1	411154.GFO_3170	1.28e-89	272.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
k59_367705_1	90814.KL370891_gene945	8.27e-110	338.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,45ZXP@72273|Thiotrichales	72273|Thiotrichales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_1440928_1	563040.Saut_1760	2.21e-48	166.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1440928_2	929558.SMGD1_0771	2e-46	149.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2YPWV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_1440928_4	563040.Saut_1757	3.88e-60	190.0	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1553692_1	1123514.KB905899_gene1000	1.7e-251	703.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,4615E@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1553692_2	1123518.ARWI01000001_gene197	1.55e-50	165.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,462JT@72273|Thiotrichales	72273|Thiotrichales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1724598_1	572480.Arnit_2631	9.7e-139	402.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1553699_1	1380384.JADN01000003_gene760	1.99e-55	182.0	COG0603@1|root,COG0603@2|Bacteria,4NSDI@976|Bacteroidetes,1I65N@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1384088_1	1121912.AUHD01000001_gene2716	3.82e-64	202.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
k59_1384088_2	985255.APHJ01000039_gene97	8.13e-45	155.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,2P766@244698|Gillisia	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
k59_651472_1	563040.Saut_0569	4.17e-77	238.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2YMTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_651472_2	929558.SMGD1_0664	2.98e-114	337.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2YMR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1553719_1	90814.KL370891_gene1717	6.94e-54	187.0	COG2165@1|root,COG2931@1|root,COG2165@2|Bacteria,COG2931@2|Bacteria,1RHE1@1224|Proteobacteria,1SFE3@1236|Gammaproteobacteria,461HT@72273|Thiotrichales	72273|Thiotrichales	NU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_28419_1	929558.SMGD1_1912	1.27e-09	57.8	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_1553741_1	1121931.AUHG01000010_gene359	2.55e-120	348.0	COG1073@1|root,COG1073@2|Bacteria,4NH47@976|Bacteroidetes,1HYN1@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9
k59_1553741_2	1121931.AUHG01000010_gene360	1.16e-34	131.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_538142_1	563040.Saut_0596	1.64e-159	450.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2YN6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_1613045_1	1270193.JARP01000003_gene2088	3.04e-191	562.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia,2NT99@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1272090_1	504487.JCM19302_535	2e-311	862.0	COG0155@1|root,COG0155@2|Bacteria,4NENW@976|Bacteroidetes,1HWQ6@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	sir	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr
k59_482409_1	338963.Pcar_2772	2.52e-43	151.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WJQV@28221|Deltaproteobacteria,43S19@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_257027_1	411154.GFO_2386	1.88e-70	220.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1HWMN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_876999_1	765911.Thivi_0290	9.75e-40	142.0	COG4566@1|root,COG4566@2|Bacteria,1NRQQ@1224|Proteobacteria,1SK9X@1236|Gammaproteobacteria,1X0II@135613|Chromatiales	135613|Chromatiales	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_142068_1	1123514.KB905899_gene1753	2.5e-31	115.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,460NX@72273|Thiotrichales	72273|Thiotrichales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_142068_2	317025.Tcr_0356	2.45e-91	271.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,460Q1@72273|Thiotrichales	72273|Thiotrichales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k59_142068_3	317025.Tcr_0355	5.56e-15	74.3	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_666884_2	367737.Abu_0022	4.41e-15	77.8	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,42X6R@68525|delta/epsilon subdivisions,2YRZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
k59_1568588_2	1231392.OCGS_1067	3.51e-53	180.0	COG2132@1|root,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Nitrite reductase	nirK	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3
k59_327642_1	1197477.IA57_02555	4.73e-133	383.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia	976|Bacteroidetes	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_327642_2	1380600.AUYN01000009_gene1224	4.15e-123	356.0	28PIV@1|root,2ZC8P@2|Bacteria,4NGE2@976|Bacteroidetes,1I08D@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k59_327642_3	641526.ADIWIN_2270	2.1e-44	153.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_725474_1	990073.ATHU01000001_gene253	1.86e-13	72.4	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2YP5U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase maturation protease	hydD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_551208_1	929558.SMGD1_0866	4e-46	158.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2YN3V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
k59_837518_1	70448.Q0P3G1	7.37e-48	161.0	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,34IHJ@3041|Chlorophyta	3041|Chlorophyta	C	ATP synthase A chain	-	-	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k59_669975_1	563040.Saut_0980	4.71e-113	345.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YR2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COGs COG0643 Chemotaxis protein histidine kinase and related kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1517515_2	1121931.AUHG01000010_gene602	5.01e-69	218.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_947527_1	1565129.JSFF01000025_gene1301	2.92e-45	150.0	COG0454@1|root,COG0456@2|Bacteria,1N0SD@1224|Proteobacteria,1S9IW@1236|Gammaproteobacteria,2QEVE@267890|Shewanellaceae	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	SO4716	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_6
k59_669981_1	945713.IALB_0159	2.17e-61	191.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,DUF559,HSDR_N,ResIII
k59_217897_1	273526.SMDB11_0207	5.6e-82	249.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,400KX@613|Serratia	1236|Gammaproteobacteria	S	glutamine amidotransferase	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_1627548_1	572480.Arnit_2605	2.64e-92	285.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2YN08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1627548_2	367737.Abu_1473	1.77e-29	115.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2YN08@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_894025_1	62928.azo1715	4.88e-63	200.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria,2KU9Y@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_894025_2	62928.azo1714	7.75e-20	87.4	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,2KU64@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_272803_1	1178825.ALIH01000004_gene2896	1.99e-217	616.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1I02Y@117743|Flavobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
k59_500019_2	1249480.B649_06940	6.68e-88	269.0	COG0667@1|root,COG0667@2|Bacteria,1RK6Z@1224|Proteobacteria,42QDH@68525|delta/epsilon subdivisions,2YNCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1571259_1	1380600.AUYN01000009_gene1489	3.65e-36	129.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
k59_1290085_1	563040.Saut_0070	7.92e-228	638.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2YNAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_45209_1	1484460.JSWG01000009_gene35	3.61e-06	47.4	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
k59_45209_2	616991.JPOO01000003_gene2603	2.93e-217	615.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia,23FP7@178469|Arenibacter	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_894054_1	1168067.JAGP01000001_gene1095	4.07e-39	141.0	2CJI1@1|root,33SDY@2|Bacteria,1NTQD@1224|Proteobacteria,1SJW7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1458136_1	90814.KL370891_gene129	2.79e-88	284.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_1458136_2	1123518.ARWI01000001_gene2383	8.08e-139	411.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg,SBP_bac_3
k59_1290098_1	1123518.ARWI01000001_gene891	6.27e-138	399.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,45ZNA@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_1401496_1	1249997.JHZW01000002_gene1142	2.05e-05	47.8	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,2PI8J@252356|Maribacter	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
k59_1222427_1	641526.ADIWIN_2219	1.26e-130	383.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1571279_1	1484460.JSWG01000015_gene905	2.33e-24	100.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_1571279_2	1121912.AUHD01000001_gene2731	2.26e-23	90.1	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia	976|Bacteroidetes	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_1571279_3	714943.Mucpa_3599	1.08e-05	47.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_105239_1	572480.Arnit_1081	2.07e-88	281.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k59_105239_2	944546.ABED_0736	1.33e-37	142.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42QY3@68525|delta/epsilon subdivisions,2YNZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,MCPsignal,dCache_1,dCache_2,sCache_2
k59_105245_1	411154.GFO_2661	3.26e-112	336.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_554314_1	1123234.AUKI01000016_gene2959	8.67e-91	291.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_837599_1	572480.Arnit_0903	1.94e-149	429.0	COG1896@1|root,COG1896@2|Bacteria,1NS5U@1224|Proteobacteria,42NW2@68525|delta/epsilon subdivisions,2YMMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
k59_218015_1	572480.Arnit_2073	1.39e-10	60.8	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_218015_2	572480.Arnit_2073	3.19e-111	331.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1686446_1	1565129.JSFF01000013_gene311	2.23e-113	339.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,2Q9XB@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	iYL1228.KPN_04331	ABC1
k59_728634_1	1123518.ARWI01000001_gene1551	2.84e-119	344.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_781838_1	504487.JCM19302_1975	6.14e-43	149.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1HY45@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
k59_781838_2	1392490.JHZX01000001_gene896	2e-68	213.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1HX7K@117743|Flavobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_1401526_1	1121931.AUHG01000011_gene1731	3.66e-42	140.0	COG3339@1|root,COG3339@2|Bacteria,4NVFR@976|Bacteroidetes,1I38F@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_1401526_2	1121931.AUHG01000011_gene1730	2.07e-104	308.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_728647_3	563040.Saut_1875	4.17e-27	100.0	2E7QP@1|root,30HJH@2|Bacteria,1Q381@1224|Proteobacteria,431QW@68525|delta/epsilon subdivisions,2YSC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1062758_1	62928.azo3063	7.27e-39	139.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KUCN@206389|Rhodocyclales	28216|Betaproteobacteria	EG	Solute carrier family 35	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1349053_1	1150600.ADIARSV_2254	3.34e-25	105.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1800147_1	1178825.ALIH01000001_gene2367	1.11e-289	819.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
k59_1458198_1	1121931.AUHG01000016_gene1125	1.18e-12	67.4	28NAV@1|root,2ZBEH@2|Bacteria,4NJGP@976|Bacteroidetes,1I0G3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1458198_2	1392490.JHZX01000001_gene1394	4.1e-35	131.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,1HZYC@117743|Flavobacteriia	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_105296_1	458817.Shal_3447	6.04e-142	413.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,1SYM5@1236|Gammaproteobacteria,2Q8MR@267890|Shewanellaceae	1236|Gammaproteobacteria	C	fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
k59_1290182_1	323850.Shew_2844	6.29e-129	384.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,2QA3E@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_45298_1	1122226.AUHX01000014_gene486	9.47e-73	229.0	COG0561@1|root,COG0561@2|Bacteria,4NG7K@976|Bacteroidetes,1HY6R@117743|Flavobacteriia	976|Bacteroidetes	S	of the HAD superfamily	supH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_1571347_1	1286632.P278_16790	1.02e-99	314.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1176990_1	411154.GFO_3416	1.86e-132	391.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_330817_1	323850.Shew_3263	3.43e-108	328.0	COG0515@1|root,COG0515@2|Bacteria,1MWEY@1224|Proteobacteria,1RQHW@1236|Gammaproteobacteria,2Q8NT@267890|Shewanellaceae	1236|Gammaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_728695_1	1123518.ARWI01000001_gene1810	6.65e-86	266.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,460TN@72273|Thiotrichales	72273|Thiotrichales	S	PFAM CobW HypB UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
k59_837661_1	1086011.HJ01_02603	5.72e-24	100.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1HY02@117743|Flavobacteriia,2NT7D@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
k59_1571371_1	317025.Tcr_1459	1.3e-110	330.0	COG1506@1|root,COG1506@2|Bacteria,1NV4Y@1224|Proteobacteria,1SNCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Protein of unknown function (DUF2920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920
k59_330848_1	1121931.AUHG01000016_gene955	3.44e-42	142.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1I176@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_330848_2	1121931.AUHG01000016_gene954	4.71e-56	182.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1HWX9@117743|Flavobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1401594_1	1123228.AUIH01000008_gene2410	5.77e-33	127.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1XITI@135619|Oceanospirillales	135619|Oceanospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1743373_1	1565129.JSFF01000009_gene1862	1.12e-97	296.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,2Q9QC@267890|Shewanellaceae	1236|Gammaproteobacteria	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317	HemX
k59_218120_1	1208321.D104_04855	1.54e-18	85.1	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1XKPI@135619|Oceanospirillales	135619|Oceanospirillales	S	esterase	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k59_781960_1	1537917.JU82_08485	1.72e-127	386.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_781960_2	563040.Saut_1905	2.61e-74	235.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_1349143_1	1123228.AUIH01000001_gene1196	1.31e-116	343.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1XHZJ@135619|Oceanospirillales	135619|Oceanospirillales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_105381_1	392500.Swoo_3291	3.46e-06	47.8	28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S2H3@1236|Gammaproteobacteria,2QEH6@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3549)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3549
k59_105381_2	1336233.JAEH01000057_gene1983	6.39e-25	97.4	COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,2QCUE@267890|Shewanellaceae	1236|Gammaproteobacteria	S	tRNA pseudouridine synthase C	yqcC	GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF446
k59_554454_1	748247.AZKH_1619	9.77e-29	106.0	2EEMQ@1|root,338FK@2|Bacteria,1NBC7@1224|Proteobacteria,2VWPQ@28216|Betaproteobacteria,2KXF2@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_554454_2	85643.Tmz1t_2809	1.67e-42	140.0	COG2104@1|root,COG2104@2|Bacteria,1N9VX@1224|Proteobacteria,2VVYE@28216|Betaproteobacteria,2KZAT@206389|Rhodocyclales	206389|Rhodocyclales	H	Mut7-C ubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
k59_330917_2	1380600.AUYN01000009_gene2139	9.84e-98	292.0	28NNN@1|root,2ZBNU@2|Bacteria,4NMJD@976|Bacteroidetes,1I1SJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_330917_3	1178825.ALIH01000006_gene1508	1.25e-36	132.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,1I1SW@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
k59_1517828_1	1172190.M947_03440	2.09e-19	83.2	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2YPZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_1517828_2	563040.Saut_1711	1.32e-68	210.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1800284_1	563040.Saut_1005	3.6e-163	463.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2YMJB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_218173_1	1137281.D778_01358	5.62e-136	408.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_894249_1	1121931.AUHG01000012_gene2795	6.21e-93	273.0	295MU@1|root,2ZSZ8@2|Bacteria,4NP18@976|Bacteroidetes,1I1YU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1419269_2	1150621.SMUL_1938	1.56e-57	187.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_685545_2	1123270.ATUR01000006_gene215	4.11e-101	314.0	2CB8B@1|root,33HNV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_685545_3	504487.JCM19302_1973	1.85e-118	352.0	COG1609@1|root,COG1609@2|Bacteria,4NE81@976|Bacteroidetes,1HZUE@117743|Flavobacteriia	976|Bacteroidetes	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
k59_1079668_1	1250006.JHZZ01000001_gene2241	1.24e-166	478.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia,3VX0E@52959|Polaribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1079668_2	1469557.JSWF01000032_gene3162	6.02e-08	55.8	COG4886@1|root,COG4886@2|Bacteria,4PNJF@976|Bacteroidetes,1HX6N@117743|Flavobacteriia	976|Bacteroidetes	C	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_967293_1	1453500.AT05_08795	3.85e-63	218.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1645531_1	1380600.AUYN01000001_gene2677	2.34e-67	209.0	COG3279@1|root,COG3279@2|Bacteria,4NFN4@976|Bacteroidetes,1HYAZ@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_1645531_2	391603.FBALC1_06593	1.19e-69	211.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1I21M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_1645531_4	504487.JCM19302_464	8.98e-70	213.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1I202@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_1136534_2	1168067.JAGP01000001_gene1523	2.13e-68	216.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria	1224|Proteobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_1024240_1	1123514.KB905899_gene1374	9.35e-20	89.7	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,45ZY0@72273|Thiotrichales	72273|Thiotrichales	EH	Anthranilate synthase component I	-	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1024240_2	1123518.ARWI01000001_gene552	8.32e-235	652.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_6954_1	1232410.KI421413_gene679	6.97e-27	103.0	2DU42@1|root,33NV9@2|Bacteria,1NJR5@1224|Proteobacteria,42XQE@68525|delta/epsilon subdivisions,2WTDU@28221|Deltaproteobacteria,43VMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Cytosol aminopeptidase family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17_N
k59_6954_2	1232410.KI421413_gene678	4.64e-21	91.3	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,43U89@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_741358_1	504487.JCM19302_2937	9.92e-170	480.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,1HYQP@117743|Flavobacteriia	976|Bacteroidetes	G	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k59_1306936_2	1380600.AUYN01000009_gene1132	2.54e-101	321.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
k59_741364_1	319224.Sputcn32_2894	1.94e-199	580.0	COG0582@1|root,COG0582@2|Bacteria,1QYZQ@1224|Proteobacteria,1RSG8@1236|Gammaproteobacteria,2QDKW@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM phage integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1136560_2	1172190.M947_04755	4.6e-79	242.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2YN3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_685585_1	765910.MARPU_08975	6.1e-52	187.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXKY@135613|Chromatiales	135613|Chromatiales	T	PFAM chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_8,PAS_9
k59_1758601_1	1380600.AUYN01000009_gene1472	2.63e-147	418.0	COG3022@1|root,COG3022@2|Bacteria,4NFP2@976|Bacteroidetes,1HZ6C@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_1758601_2	1469557.JSWF01000014_gene2515	1.35e-43	149.0	COG4700@1|root,COG4700@2|Bacteria,4NNDR@976|Bacteroidetes,1I1WB@117743|Flavobacteriia	976|Bacteroidetes	S	containing a divergent form of TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,PLDc_N,TPR_7,TPR_8
k59_1645571_1	411154.GFO_2933	2.77e-145	434.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_402829_1	411154.GFO_0663	1.91e-188	532.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,4PKKU@976|Bacteroidetes,1IJC1@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
k59_967326_1	1249975.JQLP01000001_gene3435	7.94e-42	149.0	28IQI@1|root,2Z8Q7@2|Bacteria,4NKRK@976|Bacteroidetes,1IMTY@117743|Flavobacteriia,2P7G4@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_967326_2	411154.GFO_2653	5.85e-25	102.0	COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,4NFQX@976|Bacteroidetes,1HWVN@117743|Flavobacteriia	976|Bacteroidetes	P	serves to protect cells from the toxic effects of hydrogen peroxide	katE	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel,DJ-1_PfpI
k59_572156_1	504487.JCM19302_2126	3.81e-131	393.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
k59_120113_1	504487.JCM19302_3826	9.21e-29	108.0	COG0527@1|root,COG0527@2|Bacteria,4NJDY@976|Bacteroidetes,1HYZX@117743|Flavobacteriia	976|Bacteroidetes	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120113_2	1197477.IA57_06480	4.41e-64	211.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1HYS5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_402842_1	90814.KL370891_gene862	2.27e-75	233.0	COG0500@1|root,COG2226@2|Bacteria,1NER3@1224|Proteobacteria,1S188@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_289764_1	90814.KL370891_gene1862	9.23e-186	526.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,46038@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_289764_2	391615.ABSJ01000026_gene129	1.09e-60	200.0	28JK2@1|root,2Z9CZ@2|Bacteria,1NZ1W@1224|Proteobacteria,1RYI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_63951_1	1121931.AUHG01000011_gene1694	4.59e-80	238.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1I22S@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_1249434_1	682795.AciX8_0250	5.38e-16	79.0	COG0463@1|root,COG0463@2|Bacteria,3Y63N@57723|Acidobacteria,2JKM7@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_402868_1	1123228.AUIH01000011_gene2124	2.89e-58	188.0	COG2988@1|root,COG2988@2|Bacteria,1MY48@1224|Proteobacteria,1RNZW@1236|Gammaproteobacteria,1XJSA@135619|Oceanospirillales	135619|Oceanospirillales	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	3.5.1.15	ko:K01437	ko00250,ko00340,ko01100,map00250,map00340,map01100	-	R00488,R00526	RC00064,RC00165,RC00300,RC00323	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k59_402868_2	1123228.AUIH01000012_gene57	4.6e-45	149.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1XJQK@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_741426_1	572480.Arnit_2449	1.09e-132	396.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2YMB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_1531941_1	714943.Mucpa_1683	4.28e-30	119.0	COG3537@1|root,COG3537@2|Bacteria,4NIAX@976|Bacteroidetes	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	GDPD,Glyco_hydro_92
k59_1531941_2	1158294.JOMI01000007_gene106	1.82e-239	692.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMV4@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
k59_1531941_3	1168034.FH5T_15665	2.01e-312	882.0	COG3250@1|root,COG3250@2|Bacteria,4NK0C@976|Bacteroidetes,2FQSH@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_1419362_2	1123514.KB905899_gene458	8.86e-55	171.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,460VH@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k59_1589297_1	1172190.M947_05490	1.6e-93	286.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	ko:K16076,ko:K18093	ko01501,ko02020,map01501,map02020	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.1.4,1.B.1.1.5,1.B.25.1.1	-	-	OprD,Porin_4
k59_1362161_1	411154.GFO_3486	2.23e-80	245.0	COG2197@1|root,COG2197@2|Bacteria,4NQZ6@976|Bacteroidetes,1HZDI@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
k59_1136625_1	313603.FB2170_09206	7.63e-63	206.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
k59_1136625_2	1122176.KB903553_gene3641	0.000406	44.3	COG3250@1|root,COG3250@2|Bacteria,4NHRV@976|Bacteroidetes,1IUSH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_1758670_1	1214065.BAGV01000019_gene2534	3.95e-33	119.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	nlpC	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
k59_1026336_3	983544.Lacal_0788	1.37e-82	246.0	COG4103@1|root,COG4103@2|Bacteria,4NNTQ@976|Bacteroidetes,1I292@117743|Flavobacteriia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	ENT,TerB
k59_1026336_4	1380600.AUYN01000007_gene3289	2.55e-212	605.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1HXWN@117743|Flavobacteriia	976|Bacteroidetes	K	RNA binding protein with S1 RNA-binding domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1421233_2	391612.CY0110_02324	1.21e-18	81.3	COG1917@1|root,COG1917@2|Bacteria,1G8D7@1117|Cyanobacteria,3KICM@43988|Cyanothece	1117|Cyanobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	AraC_binding,Cupin_2,Nif11
k59_66017_1	504487.JCM19302_1853	2.58e-64	202.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1HXD3@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_66017_2	1178825.ALIH01000008_gene806	6.06e-126	360.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_66017_3	1137281.D778_02412	8.69e-93	280.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1HX7A@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_1309096_1	90814.KL370891_gene1061	7.37e-38	128.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,460WD@72273|Thiotrichales	72273|Thiotrichales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1309096_2	1123518.ARWI01000001_gene214	5.78e-76	242.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales	72273|Thiotrichales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_461632_1	1380600.AUYN01000012_gene2990	1.83e-140	415.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_1026351_1	225937.HP15_2845	2.43e-85	259.0	28Z54@1|root,2ZKXF@2|Bacteria,1RAVB@1224|Proteobacteria,1S46P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	-
k59_66025_1	411154.GFO_2625	3.94e-99	316.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
k59_235783_1	305700.B447_02386	8.37e-104	329.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2VJSI@28216|Betaproteobacteria,2KWRC@206389|Rhodocyclales	206389|Rhodocyclales	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_1026365_1	1121931.AUHG01000010_gene393	6.12e-94	281.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
k59_517375_1	316067.Geob_3293	4.54e-112	352.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43SUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1251536_1	929558.SMGD1_1335	8.44e-83	258.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2YR2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_630806_1	392500.Swoo_2187	1.5e-48	162.0	COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,2QBKD@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
k59_630806_2	870967.VIS19158_21676	2.04e-48	163.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,1S0BI@1236|Gammaproteobacteria,1XTY0@135623|Vibrionales	135623|Vibrionales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_1364075_1	317025.Tcr_1352	1.8e-19	85.1	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,460DH@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_1364075_2	1123518.ARWI01000001_gene502	1.2e-122	359.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,46084@72273|Thiotrichales	72273|Thiotrichales	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
k59_1421279_1	1123518.ARWI01000001_gene2001	2.93e-152	437.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,4607E@72273|Thiotrichales	72273|Thiotrichales	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1138526_1	709032.Sulku_1514	4.35e-132	380.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,42Z77@68525|delta/epsilon subdivisions,2YRAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k59_1251564_1	317025.Tcr_0841	1.65e-167	481.0	COG0288@1|root,COG0288@2|Bacteria,1QYIQ@1224|Proteobacteria,1T3X3@1236|Gammaproteobacteria,463UR@72273|Thiotrichales	72273|Thiotrichales	P	Carboxysome Shell Carbonic Anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
k59_1251564_2	317025.Tcr_0842	4.79e-58	179.0	COG4576@1|root,COG4576@2|Bacteria,1MZNS@1224|Proteobacteria,1S9MK@1236|Gammaproteobacteria,462U2@72273|Thiotrichales	72273|Thiotrichales	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
k59_1251564_3	317025.Tcr_0843	1.48e-07	49.3	COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,1S9JX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
k59_9058_1	291985.CCSI01000001_gene2025	1.62e-32	123.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2U63R@28211|Alphaproteobacteria,2K5T5@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
k59_9058_2	1123518.ARWI01000001_gene2050	1.69e-33	124.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,460G8@72273|Thiotrichales	72273|Thiotrichales	J	class II (D, K and N)	-	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k59_1533885_1	1123514.KB905899_gene949	2.1e-94	283.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,4605V@72273|Thiotrichales	72273|Thiotrichales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_66076_1	1178825.ALIH01000003_gene2163	1.32e-194	550.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_630837_1	504487.JCM19302_679	9.62e-84	262.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_630837_2	1178825.ALIH01000001_gene2641	6.15e-50	171.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_122141_1	1168067.JAGP01000001_gene1727	3.99e-62	206.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,1RN78@1236|Gammaproteobacteria,45ZMK@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_122141_2	1190603.AJYD01000023_gene738	5.21e-47	156.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,1S6R9@1236|Gammaproteobacteria,1XWRZ@135623|Vibrionales	135623|Vibrionales	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
k59_517416_1	1123277.KB893195_gene5501	8.57e-69	243.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KNX@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_517416_2	1122179.KB890469_gene596	6.21e-107	346.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,Reg_prop,Response_reg,Y_Y_Y
k59_235848_1	768066.HELO_4183	1.75e-81	258.0	2C57E@1|root,2Z8WK@2|Bacteria,1PPA2@1224|Proteobacteria,1RZPQ@1236|Gammaproteobacteria,1XQ1G@135619|Oceanospirillales	135619|Oceanospirillales	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
k59_235848_3	1211817.CCAT010000013_gene3181	4.24e-17	77.8	2E24F@1|root,32XBM@2|Bacteria,1VE9G@1239|Firmicutes,24QG8@186801|Clostridia,36P3X@31979|Clostridiaceae	186801|Clostridia	S	ATP-binding sugar transporter from pro-phage	-	-	-	-	-	-	-	-	-	-	-	-	Gifsy-2
k59_235848_4	484770.UFO1_1702	3.99e-41	144.0	2DMPX@1|root,32SY7@2|Bacteria,1VBPX@1239|Firmicutes,4H6A1@909932|Negativicutes	909932|Negativicutes	S	Prophage minor tail protein Z (GPZ)	-	-	-	-	-	-	-	-	-	-	-	-	Minor_tail_Z
k59_235848_5	1122917.KB899685_gene3255	2.69e-11	66.2	2DNJG@1|root,32XTU@2|Bacteria,1VGKK@1239|Firmicutes,4HR43@91061|Bacilli,270DA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_687823_2	583345.Mmol_1781	1.38e-10	64.3	2DRHC@1|root,33BRH@2|Bacteria,1PGCK@1224|Proteobacteria,2WA54@28216|Betaproteobacteria,2KND2@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
k59_1043398_2	929558.SMGD1_0094	6.89e-115	332.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2YN1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_760263_1	326298.Suden_1403	4.66e-51	173.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_760263_2	563040.Saut_0775	1.8e-34	125.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2YMRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_818622_1	319224.Sputcn32_0175	5.9e-29	106.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,1S5X5@1236|Gammaproteobacteria,2QBY5@267890|Shewanellaceae	1236|Gammaproteobacteria	KT	PFAM peptidase S24	umuD	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009355,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
k59_873867_1	1499967.BAYZ01000104_gene3654	1.07e-39	139.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_196837_1	1380600.AUYN01000006_gene317	2.19e-39	144.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,1HWMR@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_364641_1	1123518.ARWI01000001_gene1450	6.34e-187	548.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales	72273|Thiotrichales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_309419_1	411154.GFO_2267	1.01e-67	217.0	COG4222@1|root,COG4222@2|Bacteria,4NHE8@976|Bacteroidetes,1HZ39@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_83756_1	944547.ABLL_0732	3.26e-131	404.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1098842_2	1178825.ALIH01000001_gene2364	8.48e-52	163.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1I3VV@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
k59_648406_1	391603.FBALC1_01352	1.78e-05	46.6	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia	976|Bacteroidetes	S	amidophosphoribosyl-transferase	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
k59_648406_2	1178825.ALIH01000001_gene2379	7.41e-133	392.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
k59_1205337_1	1178825.ALIH01000001_gene2508	1.86e-66	204.0	COG3565@1|root,COG3565@2|Bacteria,4NRZG@976|Bacteroidetes,1I304@117743|Flavobacteriia	976|Bacteroidetes	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1205337_2	1137281.D778_02748	1e-37	127.0	2E7BN@1|root,331UZ@2|Bacteria,4NV1G@976|Bacteroidetes,1I5PU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1205337_3	745718.JADT01000002_gene2321	1.18e-18	79.7	2CJFR@1|root,32RQT@2|Bacteria,4NSHX@976|Bacteroidetes,1I4E2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_760313_1	1111730.ATTM01000003_gene586	5.37e-15	80.5	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia,2NSA8@237|Flavobacterium	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_196874_1	504487.JCM19302_2788	1.29e-141	411.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_196874_2	1380600.AUYN01000007_gene3311	8.81e-146	436.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_591285_1	517417.Cpar_1595	1.08e-20	83.6	2EJKX@1|root,33DBU@2|Bacteria	2|Bacteria	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
k59_591285_2	1537917.JU82_05010	5.88e-25	95.9	2A433@1|root,30SN2@2|Bacteria,1PBWY@1224|Proteobacteria,42VT4@68525|delta/epsilon subdivisions,2YQB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1609863_1	639282.DEFDS_0383	3.87e-76	236.0	COG0463@1|root,COG0463@2|Bacteria,2GGQ5@200930|Deferribacteres	200930|Deferribacteres	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_479345_2	1122225.AULQ01000001_gene1904	5.04e-62	203.0	COG0742@1|root,COG0742@2|Bacteria,4NG6E@976|Bacteroidetes,1IJCS@117743|Flavobacteriia	976|Bacteroidetes	L	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,PCMT
k59_479352_1	1122169.AREN01000014_gene2740	1.28e-54	196.0	COG1201@1|root,COG1205@1|root,COG1201@2|Bacteria,COG1205@2|Bacteria,1MVGH@1224|Proteobacteria,1RQXN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	dEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k59_1495988_1	1443665.JACA01000050_gene2104	3.52e-49	168.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia,2YGKG@290174|Aquimarina	976|Bacteroidetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_1495988_2	1197477.IA57_07310	1.73e-36	134.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
k59_1098877_1	1123518.ARWI01000001_gene1897	3.61e-94	284.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,45ZQV@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526,ko:K03676	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03110,ko03400	-	-	-	Glutaredoxin,Ribonuc_red_sm
k59_1609881_1	1042377.AFPJ01000011_gene420	2.02e-31	123.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4649Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	ydiJ	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1609881_2	1134474.O59_002597	2.4e-16	75.1	COG0517@1|root,COG0517@2|Bacteria,1N2TU@1224|Proteobacteria,1S9T1@1236|Gammaproteobacteria,1FIAC@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_479366_1	1137281.D778_01741	1.76e-48	169.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_479366_2	1178825.ALIH01000003_gene2193	7.39e-81	241.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,1I275@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_479366_3	983544.Lacal_0931	4.87e-51	165.0	COG2128@1|root,COG2128@2|Bacteria,4NEJZ@976|Bacteroidetes,1HXPF@117743|Flavobacteriia	976|Bacteroidetes	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_760350_1	321846.PS417_16750	8.18e-34	125.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_706680_1	1137281.D778_02351	1.1e-84	281.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes,1HWSH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_8
k59_1721678_1	929558.SMGD1_2372	2.69e-59	202.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YNUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	-	-	-	ko:K14086	-	-	-	-	ko00000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_196932_1	1121931.AUHG01000011_gene1859	3.25e-110	329.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,1HWK3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
k59_196933_1	572480.Arnit_0229	1.47e-29	110.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1PMC1@1224|Proteobacteria,430UF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
k59_196933_2	572480.Arnit_0228	3.97e-49	164.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2YMNC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_253886_1	1026882.MAMP_02535	4.93e-145	426.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZPC@72273|Thiotrichales	72273|Thiotrichales	G	PFAM alpha amylase, catalytic	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_1157487_1	323848.Nmul_A0730	2.55e-44	154.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,372AK@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_1723658_1	1121931.AUHG01000011_gene1633	4.28e-47	160.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1IJXK@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1723658_2	1121931.AUHG01000011_gene1634	5.8e-99	288.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia	976|Bacteroidetes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_85847_1	1123518.ARWI01000001_gene736	3.69e-166	473.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,460BS@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_537155_1	563040.Saut_1273	4.5e-91	272.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2YMT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	motP	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_311485_1	1121931.AUHG01000010_gene871	3.88e-111	330.0	COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,1HWSM@117743|Flavobacteriia	976|Bacteroidetes	I	Long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_1552787_1	326298.Suden_0886	1.14e-43	157.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,4302Q@68525|delta/epsilon subdivisions,2YRWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_820803_1	929558.SMGD1_1240	4.42e-08	52.0	COG1699@1|root,COG1699@2|Bacteria,1N347@1224|Proteobacteria,42RNU@68525|delta/epsilon subdivisions,2YPKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
k59_931669_1	1123518.ARWI01000001_gene1936	1.27e-178	519.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,4609P@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_931669_2	90814.KL370891_gene1705	2.51e-19	82.4	COG2888@1|root,COG2888@2|Bacteria,1N3WA@1224|Proteobacteria	1224|Proteobacteria	J	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
k59_27542_1	1086011.HJ01_03435	1.22e-32	124.0	COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes,1HYTM@117743|Flavobacteriia,2NZCG@237|Flavobacterium	976|Bacteroidetes	P	PhoD-like phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
k59_27542_2	411154.GFO_0788	5.55e-24	97.8	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1612014_1	387093.SUN_1068	2.29e-178	520.0	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_593303_1	1121931.AUHG01000015_gene1252	5.68e-105	321.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HY5T@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_820813_1	90814.KL370891_gene1510	3.44e-102	301.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,460FF@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_820813_2	1123518.ARWI01000001_gene2146	4.82e-21	88.6	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4608T@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_1329445_1	1338011.BD94_0541	1.3e-87	261.0	COG2020@1|root,COG2020@2|Bacteria,4NXS4@976|Bacteroidetes,1I6PP@117743|Flavobacteriia	976|Bacteroidetes	O	Protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_1329445_2	1469557.JSWF01000025_gene1319	9.8e-07	48.9	2AVBG@1|root,31M2S@2|Bacteria,4NQIJ@976|Bacteroidetes,1I3P4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1157531_1	985255.APHJ01000034_gene2512	9.84e-50	167.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia,2P5H1@244698|Gillisia	976|Bacteroidetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_1440089_1	572480.Arnit_0053	1.33e-92	280.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42N49@68525|delta/epsilon subdivisions,2YND2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
k59_366841_1	572480.Arnit_1129	4.02e-197	559.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_709018_1	1178825.ALIH01000001_gene2308	1.22e-56	185.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1HY0U@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_876011_1	411154.GFO_1042	1.73e-76	244.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,1HY70@117743|Flavobacteriia	976|Bacteroidetes	G	COG3387 Glucoamylase and related glycosyl	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
k59_876011_2	411154.GFO_1041	2.92e-149	439.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,1HWRA@117743|Flavobacteriia	976|Bacteroidetes	G	COG0380 Trehalose-6-phosphate synthase	otsB	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
k59_1781044_2	411154.GFO_2101	1.47e-76	235.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1HYH7@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1781057_1	572480.Arnit_1917	1.96e-100	315.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_876025_2	1197477.IA57_02970	5.44e-69	213.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1I1AX@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_876025_3	1469557.JSWF01000032_gene3095	1.63e-33	122.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1HX4S@117743|Flavobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_27607_1	391587.KAOT1_20677	8.4e-19	89.4	COG4872@1|root,COG4872@2|Bacteria,4NIK7@976|Bacteroidetes,1HZVF@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
k59_366880_1	1380600.AUYN01000001_gene2578	5.16e-96	280.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_366880_2	504487.JCM19302_287	4.09e-109	327.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1383222_1	1167632.AJTR01000122_gene1212	4.68e-06	47.4	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,4GXW4@90964|Staphylococcaceae	91061|Bacilli	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1101021_1	411154.GFO_1514	1.73e-155	440.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1HWV1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
k59_1101021_2	411154.GFO_1515	2.24e-27	102.0	COG1051@1|root,COG1051@2|Bacteria,4NSQ1@976|Bacteroidetes,1I3GH@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_1498236_1	90814.KL370891_gene1239	2.39e-99	297.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,45ZTJ@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1498236_2	1123519.PSJM300_02985	1.71e-15	74.3	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1Z2FT@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_85966_1	90814.KL370891_gene1718	3.1e-10	70.5	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,1SFE3@1236|Gammaproteobacteria,461HT@72273|Thiotrichales	72273|Thiotrichales	NU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1206631_1	62977.ACIAD1454	3.74e-20	88.6	COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,1RNSV@1236|Gammaproteobacteria,3NIRI@468|Moraxellaceae	1236|Gammaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k59_1206631_2	298386.PBPRA2119	1.87e-28	110.0	COG0583@1|root,COG0583@2|Bacteria,1MZZP@1224|Proteobacteria,1RNX9@1236|Gammaproteobacteria,1XU95@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1440183_1	411154.GFO_2625	1.51e-84	276.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
k59_1383267_1	1380600.AUYN01000008_gene3439	4.71e-81	270.0	COG4932@1|root,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_984058_1	1123518.ARWI01000001_gene1776	1.85e-54	186.0	COG2863@1|root,COG2863@2|Bacteria,1N7NU@1224|Proteobacteria,1SH3Q@1236|Gammaproteobacteria,463A7@72273|Thiotrichales	72273|Thiotrichales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1723825_1	717773.Thicy_0476	1.17e-28	104.0	COG5007@1|root,COG5007@2|Bacteria,1PZMG@1224|Proteobacteria,1SGB5@1236|Gammaproteobacteria,462UV@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
k59_1723825_2	90814.KL370891_gene511	3.53e-127	367.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46014@72273|Thiotrichales	72273|Thiotrichales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_256166_1	1307437.J139_17129	7.54e-67	211.0	COG0338@1|root,COG0338@2|Bacteria,1QDNB@1224|Proteobacteria,1RXZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MethyltransfD12
k59_1781153_1	983544.Lacal_0252	1.69e-102	306.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1HYUA@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1781153_2	1380600.AUYN01000003_gene26	9.89e-155	447.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1HXQA@117743|Flavobacteriia	976|Bacteroidetes	CP	ABC transporter (Permease)	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_876145_1	945713.IALB_1383	5.68e-84	254.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1099	AAA_28,Thymidylate_kin
k59_1572090_3	1172190.M947_03690	8.44e-09	52.4	COG2944@1|root,COG2944@2|Bacteria,1Q2M2@1224|Proteobacteria,42VXE@68525|delta/epsilon subdivisions,2YQ6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_671007_2	90813.JQMT01000001_gene2168	4.07e-31	119.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,4604T@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
k59_1003948_1	90814.KL370891_gene885	9.08e-55	178.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,460EY@72273|Thiotrichales	72273|Thiotrichales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1003948_2	29495.EA26_18565	1.1e-08	55.8	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XTPC@135623|Vibrionales	135623|Vibrionales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_1063655_1	745277.GRAQ_00578	1.03e-16	77.8	COG5005@1|root,COG5005@2|Bacteria,1MZCV@1224|Proteobacteria,1S4IA@1236|Gammaproteobacteria,3FIDG@34037|Rahnella	1236|Gammaproteobacteria	S	Phage virion morphogenesis family	S	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_S
k59_1063655_2	1124991.MU9_2048	1.16e-12	65.9	2CBI4@1|root,32RTF@2|Bacteria,1MZ82@1224|Proteobacteria,1S5DY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P2 phage tail completion R family protein	R	-	-	-	-	-	-	-	-	-	-	-	P2_Phage_GpR
k59_1572113_1	411154.GFO_2958	6.17e-218	603.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia	976|Bacteroidetes	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_1572113_2	1121931.AUHG01000019_gene3048	2e-176	494.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1HWJM@117743|Flavobacteriia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1572113_3	1121931.AUHG01000019_gene3047	1.4e-103	301.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1I35P@117743|Flavobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
k59_1572113_4	411154.GFO_2961	6.29e-45	159.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1572117_1	1123518.ARWI01000001_gene1107	6.73e-46	149.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,461H7@72273|Thiotrichales	72273|Thiotrichales	S	YcgL domain	-	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
k59_1521700_1	62928.azo2198	4.73e-127	373.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,2KUNN@206389|Rhodocyclales	206389|Rhodocyclales	T	ATPase related to phosphate starvation-inducible protein PhoH	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1124093_1	929558.SMGD1_2276	9.72e-06	49.3	COG0810@1|root,COG0810@2|Bacteria,1QAAM@1224|Proteobacteria,42X9R@68525|delta/epsilon subdivisions,2YQQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
k59_1352918_1	411154.GFO_3053	1.62e-107	321.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_163156_1	768066.HELO_1213	4.1e-39	144.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XHC0@135619|Oceanospirillales	135619|Oceanospirillales	E	Oligopeptidase	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_163156_2	1461580.CCAS010000024_gene2483	3.1e-41	142.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,4HH7M@91061|Bacilli,1ZHKI@1386|Bacillus	91061|Bacilli	S	GyrI-like small molecule binding domain	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	GyrI-like
k59_1747197_1	411154.GFO_2402	2.85e-54	177.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1352923_1	945713.IALB_1687	6.31e-54	182.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM_1	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_673896_1	929558.SMGD1_1362	7.73e-144	410.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2YMNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_897705_1	90814.KL370891_gene1316	9.09e-67	206.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_897705_2	1123518.ARWI01000001_gene2406	1.56e-63	207.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,460B0@72273|Thiotrichales	72273|Thiotrichales	T	PFAM PhoH-like protein	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1629930_1	1565129.JSFF01000029_gene3014	6.91e-101	310.0	COG2199@1|root,COG2200@1|root,COG2770@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2770@2|Bacteria,1QVWQ@1224|Proteobacteria,1T2KZ@1236|Gammaproteobacteria,2Q8TT@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K18765	-	-	-	-	ko00000,ko03019	-	-	-	EAL,GGDEF,HAMP,LapD_MoxY_N
k59_1066361_1	1484460.JSWG01000004_gene2647	2.31e-42	147.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_613835_1	1232410.KI421424_gene1702	1.45e-26	104.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,43S0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_613835_2	526222.Desal_3303	2.05e-64	207.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2M87G@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
k59_163178_1	929558.SMGD1_0606	2.04e-56	183.0	COG2908@1|root,COG2908@2|Bacteria,1Q1QY@1224|Proteobacteria,42STS@68525|delta/epsilon subdivisions,2YP6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
k59_732607_1	1172190.M947_06800	8.04e-37	125.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2YPEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_732607_2	929558.SMGD1_0768	5.88e-142	403.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2YM7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_732607_3	929558.SMGD1_0769	4.94e-13	66.2	COG0806@1|root,COG0806@2|Bacteria,1MYUH@1224|Proteobacteria,42SEN@68525|delta/epsilon subdivisions,2YPH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_840466_1	1565129.JSFF01000003_gene2169	1.32e-16	78.6	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,2Q8XR@267890|Shewanellaceae	1236|Gammaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_840466_2	637905.SVI_2332	4.02e-37	130.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,2QBY9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_1006980_1	572480.Arnit_0211	2.45e-132	385.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_1124178_1	317025.Tcr_2044	3e-43	146.0	COG2215@1|root,COG2215@2|Bacteria	2|Bacteria	O	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1124178_2	1123514.KB905899_gene608	1.28e-46	159.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,460PT@72273|Thiotrichales	72273|Thiotrichales	P	Eukaryotic-type carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_503878_1	944547.ABLL_1252	1.34e-20	94.4	2AN97@1|root,32J0R@2|Bacteria,1PCA3@1224|Proteobacteria,42T7U@68525|delta/epsilon subdivisions,2YPPF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
k59_503878_2	867902.Ornrh_0249	1.6e-07	50.4	COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes,1I40J@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_334828_1	1178825.ALIH01000007_gene1735	1.59e-99	298.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,1HXDI@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_785936_1	1392490.JHZX01000001_gene2618	1.68e-95	296.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1352995_1	563040.Saut_0703	1.1e-28	106.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2YPXJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_1352995_2	563040.Saut_0702	1.23e-58	183.0	COG0858@1|root,COG0858@2|Bacteria,1Q48R@1224|Proteobacteria,42UQE@68525|delta/epsilon subdivisions,2YPZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_1352995_3	929558.SMGD1_2178	1.35e-98	310.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1226581_1	323850.Shew_0440	2.88e-101	301.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,2QAUV@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_389818_1	991.IW20_10875	2.57e-95	305.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia,2NS6Z@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_163247_1	391603.FBALC1_14197	3.92e-101	316.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia	976|Bacteroidetes	CI	phenylacetic acid degradation protein paaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
k59_109089_1	1469557.JSWF01000029_gene3305	2.02e-35	135.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_1574650_1	572480.Arnit_2834	2.44e-107	317.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42RI9@68525|delta/epsilon subdivisions,2YP40@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_1521822_2	317025.Tcr_0856	7.95e-167	471.0	COG4286@1|root,COG4286@2|Bacteria,1MVTY@1224|Proteobacteria,1RYWZ@1236|Gammaproteobacteria,462Y8@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
k59_1521822_4	317025.Tcr_1779	2.28e-146	423.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,460F3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
k59_1294102_2	1487953.JMKF01000053_gene1774	1.08e-30	119.0	COG0334@1|root,COG0334@2|Bacteria,1G0WP@1117|Cyanobacteria,1H98K@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
k59_1066453_1	1123228.AUIH01000005_gene602	6.1e-101	308.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XI13@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_785975_1	1123514.KB905899_gene885	4.09e-169	478.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,4605F@72273|Thiotrichales	72273|Thiotrichales	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
k59_1404889_1	572480.Arnit_0512	3.69e-110	343.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_674017_1	504487.JCM19302_1436	7.72e-52	174.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_674017_2	1178825.ALIH01000003_gene2048	9.45e-193	570.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_785986_1	945713.IALB_0303	9.72e-85	264.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,HAMP,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1124244_2	1042376.AFPK01000054_gene2296	1.86e-75	226.0	COG2963@1|root,COG2963@2|Bacteria,4NP72@976|Bacteroidetes,1I2BH@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_1521852_1	929556.Solca_3209	3.38e-54	192.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_674037_1	1211777.BN77_2526	1.78e-135	407.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,4B9AV@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_1180952_1	1235457.C404_23300	7.3e-90	273.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,1K4JH@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_1747374_1	1392490.JHZX01000001_gene587	4.59e-56	188.0	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1404931_1	1442598.JABW01000010_gene200	9.07e-61	202.0	2AI50@1|root,318J7@2|Bacteria,1Q0GX@1224|Proteobacteria,42S3J@68525|delta/epsilon subdivisions,2YP5Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Annotation was generated automatically without manual curation	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k59_732767_2	1002672.SAR11G3_01019	2.63e-15	79.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,4BPCM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_1294186_2	1250006.JHZZ01000001_gene1856	2.11e-95	285.0	COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,1I1FX@117743|Flavobacteriia,3VWXQ@52959|Polaribacter	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
k59_49010_1	1537917.JU82_07125	2.38e-12	66.2	COG1413@1|root,COG1413@2|Bacteria,1NMDT@1224|Proteobacteria,42WYR@68525|delta/epsilon subdivisions,2YQSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_49010_2	1249480.B649_11555	7.73e-32	115.0	2AJ5V@1|root,319QG@2|Bacteria,1Q3K7@1224|Proteobacteria,42XFR@68525|delta/epsilon subdivisions,2YQU7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1124312_1	1123228.AUIH01000040_gene2924	5.34e-10	58.5	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XHJU@135619|Oceanospirillales	135619|Oceanospirillales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_1124312_2	1123228.AUIH01000040_gene2923	2.25e-72	225.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1XI5A@135619|Oceanospirillales	135619|Oceanospirillales	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_1180998_2	1415754.JQMK01000005_gene1690	1.87e-06	48.9	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,4650K@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k59_840638_1	1178825.ALIH01000003_gene2074	1.06e-106	323.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_840638_2	504487.JCM19302_1478	2.4e-82	244.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia	976|Bacteroidetes	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_614031_1	326298.Suden_0003	8.66e-91	287.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1353132_1	1223410.KN050846_gene1591	1.03e-66	206.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_1353132_2	1249997.JHZW01000002_gene1278	7.34e-187	532.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia,2PICB@252356|Maribacter	976|Bacteroidetes	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
k59_1294208_1	1172190.M947_06775	1.63e-179	509.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_49034_1	572547.Amico_1114	6.1e-113	339.0	COG3497@1|root,COG3497@2|Bacteria,3TAKX@508458|Synergistetes	508458|Synergistetes	S	tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	-
k59_446683_1	929558.SMGD1_2824	5.43e-13	69.7	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions,2YQ7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_446683_2	1172190.M947_01860	4.65e-36	134.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1690531_2	929558.SMGD1_1230	2.67e-61	194.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2YNGY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1353165_1	980584.AFPB01000087_gene206	2.23e-26	112.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_857522_2	86106.I862_00290	7.85e-23	96.7	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,47EYG@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1479205_1	411154.GFO_3546	1.08e-72	235.0	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
k59_1422608_1	326298.Suden_0714	1.2e-81	255.0	28NUA@1|root,2ZBSQ@2|Bacteria,1QE31@1224|Proteobacteria,42Z7U@68525|delta/epsilon subdivisions,2YR9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1705337_1	1380600.AUYN01000012_gene2981	1.1e-178	508.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_744693_1	425104.Ssed_2292	1.44e-104	319.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,2Q8TM@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_801929_1	572480.Arnit_2872	5.89e-73	235.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1027835_2	1117647.M5M_10800	6.36e-73	233.0	COG3637@1|root,COG3637@2|Bacteria,1PXDF@1224|Proteobacteria,1TC33@1236|Gammaproteobacteria,1JBGY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_632229_1	983544.Lacal_0417	7.17e-20	89.4	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_406322_1	234267.Acid_5651	7.63e-77	242.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_406322_2	1379698.RBG1_1C00001G0296	2.25e-88	269.0	COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	ttrB	-	-	ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_7
k59_1479241_2	1123514.KB905901_gene159	7.75e-63	200.0	COG3063@1|root,COG3063@2|Bacteria,1R2PW@1224|Proteobacteria	1224|Proteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_744710_1	1336233.JAEH01000011_gene2835	3.59e-128	370.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,2QADP@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
k59_1083107_1	1137281.D778_00262	2.13e-62	213.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
k59_1139811_1	411154.GFO_0993	5.49e-94	276.0	COG3296@1|root,COG3296@2|Bacteria,4NUD1@976|Bacteroidetes,1I4G4@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
k59_67492_1	1123518.ARWI01000001_gene340	1.34e-67	225.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_1139814_1	1123518.ARWI01000001_gene912	8.44e-151	435.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,4600H@72273|Thiotrichales	72273|Thiotrichales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_632240_2	381666.H16_B1328	2.75e-10	62.0	2EDG7@1|root,337CE@2|Bacteria,1NBT7@1224|Proteobacteria,2VW08@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3693,HTH_3
k59_632240_7	265072.Mfla_0975	1.78e-90	289.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,2VM3H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	replication	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k59_1535212_1	1122605.KB893626_gene2477	4.65e-41	144.0	COG1470@1|root,COG1470@2|Bacteria,4NHIX@976|Bacteroidetes,1IQI7@117747|Sphingobacteriia	976|Bacteroidetes	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
k59_1535212_2	1121272.KB903254_gene6632	1.12e-10	62.8	COG4152@1|root,COG4152@2|Bacteria,2I2U6@201174|Actinobacteria,4DMD2@85008|Micromonosporales	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	AAA_21,ABC_tran,DUF4162
k59_801963_1	1122201.AUAZ01000015_gene775	1.2e-25	105.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,464RX@72275|Alteromonadaceae	1236|Gammaproteobacteria	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C,RLAN,RimK
k59_801963_2	1123514.KB905899_gene1994	3.6e-36	130.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,1S0KZ@1236|Gammaproteobacteria,463AF@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
k59_293287_1	317025.Tcr_1794	7.75e-20	88.2	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,4607W@72273|Thiotrichales	72273|Thiotrichales	M	sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
k59_1422654_1	1172190.M947_10750	3.38e-37	131.0	2AIU4@1|root,319B6@2|Bacteria,1Q28N@1224|Proteobacteria,42V6E@68525|delta/epsilon subdivisions,2YQ6D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1422654_2	563040.Saut_1220	4.33e-44	145.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42VGZ@68525|delta/epsilon subdivisions,2YQ8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_801971_1	929558.SMGD1_2416	1.94e-185	532.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_1762173_1	1121931.AUHG01000010_gene850	1.56e-175	498.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_463197_1	945713.IALB_1779	6.14e-109	323.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_575733_1	1123518.ARWI01000001_gene1862	3.8e-124	382.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,462HX@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1649075_1	1347342.BN863_16110	0.0	1058.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HYMP@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1649075_2	1347342.BN863_16100	7.42e-99	304.0	28I8D@1|root,2Z8B7@2|Bacteria,4NN38@976|Bacteroidetes,1IIB2@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
k59_1083153_1	1117318.PRUB_24245	1.38e-33	129.0	COG2169@1|root,COG2169@2|Bacteria,1QVP1@1224|Proteobacteria,1S34S@1236|Gammaproteobacteria,2Q2JI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	F	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_10436_3	313603.FB2170_12601	4.72e-97	293.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1I0TY@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10436_5	1121875.KB907546_gene2674	5.36e-18	82.4	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes,1I01K@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
k59_1139855_1	563040.Saut_0788	2.89e-98	290.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,42MBG@68525|delta/epsilon subdivisions,2YMHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	pfs	-	3.2.2.30,3.2.2.9	ko:K18284	ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R10668	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_293332_1	1123514.KB905899_gene925	1.44e-244	698.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,45ZMI@72273|Thiotrichales	72273|Thiotrichales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_689324_1	1123326.JFBL01000013_gene371	8.41e-103	306.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2YMDZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	acid synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_180766_1	945713.IALB_2179	5.17e-98	300.0	COG0459@1|root,COG0459@2|Bacteria	2|Bacteria	O	protein refolding	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1705452_1	1336803.PHEL49_1573	1.29e-20	89.7	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1HXH7@117743|Flavobacteriia,3VW11@52959|Polaribacter	976|Bacteroidetes	J	16S rRNA methyltransferase RsmB/F	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_1705452_2	362418.IW19_07860	2.43e-95	302.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,2NUJG@237|Flavobacterium	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
k59_1535273_1	929713.NIASO_04145	2.67e-52	170.0	2DSN4@1|root,33GRH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_123533_1	926559.JoomaDRAFT_1850	1.99e-207	594.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1HWNZ@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1310672_1	1163407.UU7_13688	1.52e-28	113.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC
k59_1705462_1	1123514.KB905899_gene989	4.67e-120	357.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,45ZP0@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_293362_1	223926.28808762	2.08e-41	150.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
k59_67587_1	313590.MED134_13936	7.3e-127	399.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia,37EIY@326319|Dokdonia	976|Bacteroidetes	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_969884_1	1121931.AUHG01000010_gene852	2.11e-102	306.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_518971_1	469383.Cwoe_5660	0.000185	48.5	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
k59_293381_1	411154.GFO_0360	6.03e-98	311.0	COG2197@1|root,COG3292@1|root,COG2197@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_237407_1	1380600.AUYN01000006_gene484	1.9e-86	279.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HXVC@117743|Flavobacteriia	976|Bacteroidetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
k59_1479392_1	411154.GFO_1553	7.76e-86	255.0	COG0782@1|root,COG0782@2|Bacteria,4NM9C@976|Bacteroidetes,1I2YK@117743|Flavobacteriia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB
k59_1479392_2	411154.GFO_1554	1.17e-08	55.8	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1HXS8@117743|Flavobacteriia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_293395_1	1178825.ALIH01000001_gene2626	1.28e-161	469.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_349205_2	392500.Swoo_4496	3.56e-23	97.4	2E2CK@1|root,32XHJ@2|Bacteria,1N6MB@1224|Proteobacteria,1SATR@1236|Gammaproteobacteria,2QB3P@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1194067_1	1150600.ADIARSV_1900	1.12e-26	110.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1194067_2	391009.Tmel_1863	8.74e-05	45.1	COG0736@1|root,COG0801@1|root,COG0736@2|Bacteria,COG0801@2|Bacteria,2GCZY@200918|Thermotogae	200918|Thermotogae	I	Belongs to the P-Pant transferase superfamily	acpS	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ACPS,HPPK
k59_349206_1	411154.GFO_2271	1.98e-113	348.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1HXTQ@117743|Flavobacteriia	976|Bacteroidetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_123589_1	1137281.D778_00268	5.33e-86	270.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1253110_1	1123228.AUIH01000069_gene2634	5.9e-93	303.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1XN5H@135619|Oceanospirillales	135619|Oceanospirillales	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_237431_1	317025.Tcr_1626	2.76e-74	231.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,4623F@72273|Thiotrichales	72273|Thiotrichales	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_237431_2	90814.KL370891_gene585	2.96e-86	267.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,45ZYW@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_349215_1	1353528.DT23_18185	3.43e-89	284.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2XM4U@285107|Thioclava	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_1365616_1	999141.GME_06065	5.99e-42	147.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1RS0P@1236|Gammaproteobacteria,1XJIN@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_123612_1	90814.KL370891_gene1025	8.44e-113	341.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,4608M@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_575860_1	317025.Tcr_0425	6.56e-25	100.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,463P8@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator, LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_575860_2	317025.Tcr_0424	0.0	900.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RYJX@1236|Gammaproteobacteria,46213@72273|Thiotrichales	72273|Thiotrichales	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_1310773_1	1107311.Q767_05935	2.14e-34	135.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia,2NSPN@237|Flavobacterium	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1649205_2	391603.FBALC1_01022	4.53e-113	335.0	COG3712@1|root,COG3712@2|Bacteria,4NJA2@976|Bacteroidetes,1HYI5@117743|Flavobacteriia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_1649205_3	1178825.ALIH01000004_gene2951	3.23e-87	260.0	COG1595@1|root,COG1595@2|Bacteria,4NMSP@976|Bacteroidetes,1I1J2@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1649205_4	1004149.AFOE01000041_gene1136	9.34e-05	46.6	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_632427_1	411154.GFO_1535	4.48e-140	408.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	res	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_1253133_1	1121889.AUDM01000005_gene1738	4.83e-91	284.0	COG0739@1|root,COG2273@1|root,COG0739@2|Bacteria,COG2273@2|Bacteria,4PM7U@976|Bacteroidetes,1IJMV@117743|Flavobacteriia,2NXE1@237|Flavobacterium	976|Bacteroidetes	GM	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1253133_2	1265503.KB905160_gene2869	3.81e-145	418.0	COG5309@1|root,COG5309@2|Bacteria,1Q5JR@1224|Proteobacteria,1SJJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_1253133_3	1123037.AUDE01000008_gene733	2.93e-172	485.0	COG5309@1|root,COG5309@2|Bacteria,4NIVF@976|Bacteroidetes,1I014@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_1253133_4	391598.FBBAL38_00260	1.16e-29	117.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia	976|Bacteroidetes	G	COG2211 Na melibiose symporter and related	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
k59_463365_1	504487.JCM19302_3817	6.05e-154	433.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
k59_463365_2	1178825.ALIH01000001_gene2317	1.65e-68	218.0	COG2234@1|root,COG2234@2|Bacteria,4NMZ4@976|Bacteroidetes,1HWZ9@117743|Flavobacteriia	976|Bacteroidetes	OU	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_803746_1	504487.JCM19302_3032	5.25e-100	295.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1HX2J@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_859539_1	264731.PRU_0054	4.03e-23	97.1	COG0017@1|root,COG0017@2|Bacteria,4P1UJ@976|Bacteroidetes	976|Bacteroidetes	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1481298_1	1123518.ARWI01000001_gene2265	5.84e-182	518.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4602R@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_1481298_2	1123518.ARWI01000001_gene2264	3.74e-144	426.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_592340_1	929558.SMGD1_2676	1.21e-18	84.0	COG0770@1|root,COG0770@2|Bacteria,1Q5GZ@1224|Proteobacteria,42RQ8@68525|delta/epsilon subdivisions,2YP4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_592340_2	1172190.M947_00495	3.37e-89	280.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2YMYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k59_1551811_1	1123514.KB905899_gene1731	2.06e-103	318.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,45ZXG@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_982911_1	563040.Saut_1266	3.27e-161	466.0	COG0668@1|root,COG3206@1|root,COG0668@2|Bacteria,COG3206@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1156492_1	709032.Sulku_0706	7.92e-130	381.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42UPM@68525|delta/epsilon subdivisions,2YRIE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_310510_1	572480.Arnit_1135	1.2e-31	117.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k59_310510_2	572480.Arnit_1134	5.39e-29	110.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_254945_1	1121931.AUHG01000012_gene2865	1.26e-291	810.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,1HWRA@117743|Flavobacteriia	976|Bacteroidetes	G	COG0380 Trehalose-6-phosphate synthase	otsB	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
k59_819789_2	572480.Arnit_3124	1.66e-67	209.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42SHB@68525|delta/epsilon subdivisions,2YP3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_930726_2	1123518.ARWI01000001_gene2090	3.1e-164	470.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,46072@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1497092_1	90814.KL370891_gene1032	9.93e-277	790.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales	72273|Thiotrichales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_930730_1	1380600.AUYN01000009_gene1324	2.15e-102	332.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2
k59_254962_1	1121931.AUHG01000011_gene1974	3.68e-148	436.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Biotin_lipoyl,Na_Ala_symp,SprB
k59_1666274_1	1038866.KB902789_gene2630	4.27e-27	106.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,3JR2J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_1666274_2	1458357.BG58_36260	2.83e-53	176.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2VN5A@28216|Betaproteobacteria,1K4RJ@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_197986_1	1137281.D778_01154	8.49e-155	447.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
k59_1328455_1	1380600.AUYN01000009_gene967	1.63e-94	308.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_1206003_1	985255.APHJ01000027_gene910	1.65e-116	343.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia,2P5S5@244698|Gillisia	976|Bacteroidetes	C	NQR2, RnfD, RnfE family	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_480489_1	1123518.ARWI01000001_gene1867	1.36e-23	99.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4624A@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_480489_2	317025.Tcr_1820	2.05e-121	369.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,4608V@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_1611019_1	1249975.JQLP01000001_gene2863	2.74e-119	348.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,1HXPJ@117743|Flavobacteriia,2P65X@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
k59_140159_1	504487.JCM19302_537	6.75e-110	320.0	COG1648@1|root,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1HYI1@117743|Flavobacteriia	976|Bacteroidetes	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
k59_140159_2	1380600.AUYN01000009_gene1208	2.53e-51	171.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_310559_1	745718.JADT01000001_gene1797	9.47e-87	282.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1551865_1	865937.Gilli_2215	4.56e-49	171.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,2P602@244698|Gillisia	976|Bacteroidetes	L	UvrC Helix-hairpin-helix N-terminal	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_1551865_2	411154.GFO_3172	5.57e-28	112.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_536254_1	1123518.ARWI01000001_gene1045	3.68e-217	639.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1780047_1	1095769.CAHF01000005_gene1527	4.12e-24	97.4	COG2105@1|root,COG2105@2|Bacteria,1NEI1@1224|Proteobacteria,2W3FC@28216|Betaproteobacteria,477M4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
k59_26665_1	411154.GFO_3581	3.43e-86	266.0	28II1@1|root,2Z8J7@2|Bacteria,4NFJH@976|Bacteroidetes,1HXNM@117743|Flavobacteriia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
k59_1439168_2	1178825.ALIH01000004_gene2858	3.51e-102	300.0	COG1187@1|root,COG1187@2|Bacteria,4NM4U@976|Bacteroidetes,1I18U@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_1439168_3	1178825.ALIH01000004_gene2857	9.19e-246	695.0	COG0550@1|root,COG0550@2|Bacteria,4NE6R@976|Bacteroidetes,1HWYU@117743|Flavobacteriia	976|Bacteroidetes	L	DNA topoisomerase	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k59_592433_1	338963.Pcar_1854	6.34e-14	70.9	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,43SK4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_592433_2	909663.KI867150_gene2748	9.1e-50	167.0	COG1651@1|root,COG1651@2|Bacteria,1Q1DW@1224|Proteobacteria,43A6N@68525|delta/epsilon subdivisions,2X21F@28221|Deltaproteobacteria,2MRNB@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Disulfide bond isomerase protein N-terminus	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_707953_1	1168067.JAGP01000001_gene906	4.22e-53	189.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,461S8@72273|Thiotrichales	72273|Thiotrichales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_875100_1	1232410.KI421428_gene987	6.57e-57	190.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,42N2R@68525|delta/epsilon subdivisions,2WJF4@28221|Deltaproteobacteria,43RZC@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k59_983005_1	929558.SMGD1_2084	2.02e-161	462.0	COG0446@1|root,COG0446@2|Bacteria,1PWV7@1224|Proteobacteria,42QCM@68525|delta/epsilon subdivisions,2YND4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1252 NADH dehydrogenase FAD-containing subunit	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_310608_1	313590.MED134_11861	1.51e-09	57.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1HWSB@117743|Flavobacteriia,37E94@326319|Dokdonia	976|Bacteroidetes	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_310608_2	1347342.BN863_28000	2.66e-22	97.8	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
k59_1722809_1	1123518.ARWI01000001_gene251	6.39e-74	233.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,46027@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1780084_1	458817.Shal_1212	8.38e-31	119.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,2Q9MV@267890|Shewanellaceae	1236|Gammaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1780084_2	1565129.JSFF01000005_gene2387	4.54e-35	129.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1RS3Z@1236|Gammaproteobacteria,2QAWZ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1666369_1	1178825.ALIH01000012_gene1819	5.74e-83	266.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia	976|Bacteroidetes	EM	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
k59_1382310_1	926559.JoomaDRAFT_2189	8.99e-68	224.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_1206062_1	1232410.KI421418_gene2169	1.58e-61	191.0	COG1145@1|root,COG1145@2|Bacteria,1NUEE@1224|Proteobacteria,42ZMC@68525|delta/epsilon subdivisions,2WUUG@28221|Deltaproteobacteria,43UQ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1206062_2	1232410.KI421418_gene2168	1.05e-33	117.0	2DG4U@1|root,2ZUHZ@2|Bacteria,1P7P1@1224|Proteobacteria,432VB@68525|delta/epsilon subdivisions,2WXHT@28221|Deltaproteobacteria,43VWC@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_708024_1	697282.Mettu_3938	1.89e-22	94.7	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,1T2MP@1236|Gammaproteobacteria,1XH0U@135618|Methylococcales	135618|Methylococcales	V	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_708024_2	1123392.AQWL01000010_gene2283	1.47e-41	152.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2WGGY@28216|Betaproteobacteria,1KSCB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_365964_1	316067.Geob_2842	2.22e-23	102.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
k59_26743_1	1123053.AUDG01000004_gene3426	1.45e-22	102.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales	135613|Chromatiales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1666395_2	1123514.KB905899_gene845	1.56e-24	102.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4114,FecR,He_PIG,HemolysinCabind,Hint_2,Lyase_8,Lyase_N,Lyase_catalyt,Peptidase_M10_C
k59_365976_1	411154.GFO_2125	9.83e-97	291.0	2C57D@1|root,2Z7RS@2|Bacteria,4NEKN@976|Bacteroidetes,1HXT2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
k59_140290_1	1444309.JAQG01000062_gene9	3.64e-24	104.0	COG4542@1|root,COG4542@2|Bacteria,1TSJB@1239|Firmicutes,4HAI3@91061|Bacilli,26VYK@186822|Paenibacillaceae	91061|Bacilli	Q	GHMP kinases N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_N
k59_310687_1	1197477.IA57_09365	7.69e-96	297.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_310687_2	504487.JCM19302_1778	1.21e-11	63.2	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_592519_1	1250005.PHEL85_3176	6.45e-48	171.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia,3VWZU@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_592519_2	1250006.JHZZ01000001_gene1107	1.86e-163	469.0	COG3507@1|root,COG3507@2|Bacteria,4PKZY@976|Bacteroidetes,1HZ0G@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k59_1100132_1	90814.KL370891_gene132	1.9e-66	213.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1RR2D@1236|Gammaproteobacteria,460S3@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1100132_2	1123518.ARWI01000001_gene1161	1.62e-13	68.9	COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_1666417_1	411154.GFO_3385	2.44e-20	84.7	2E4I5@1|root,32ZD8@2|Bacteria,4NV9B@976|Bacteroidetes,1I50D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1666417_2	1121931.AUHG01000010_gene371	3.05e-81	244.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1HWRQ@117743|Flavobacteriia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_708063_1	1123518.ARWI01000001_gene1862	1.39e-111	347.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,462HX@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_1100134_2	929558.SMGD1_1861	3.58e-54	169.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2YPHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_1100134_3	563040.Saut_1711	1.3e-06	51.2	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_198143_1	392500.Swoo_0501	1.7e-50	178.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,1RPS2@1236|Gammaproteobacteria,2QBCR@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Type I restriction modification DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_877057_1	391603.FBALC1_05473	1.44e-44	148.0	2E6RI@1|root,331BM@2|Bacteria,4NVRD@976|Bacteroidetes,1I5B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_877057_2	1270193.JARP01000007_gene169	1.12e-44	150.0	COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes,1I1AF@117743|Flavobacteriia,2NSF3@237|Flavobacterium	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k59_651615_1	655815.ZPR_0579	7.46e-107	328.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_651615_2	411154.GFO_0163	1.7e-32	116.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
k59_200005_1	411154.GFO_3017	7.91e-287	802.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_932665_1	1120950.KB892709_gene4105	4.13e-10	62.8	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4DQEV@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_932665_2	991.IW20_25595	2.15e-26	102.0	COG0454@1|root,COG0456@2|Bacteria,4NMCW@976|Bacteroidetes,1I2KA@117743|Flavobacteriia,2NUZ9@237|Flavobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_1782113_1	1121935.AQXX01000139_gene3007	1.08e-15	75.1	COG0835@1|root,COG0835@2|Bacteria,1ND5U@1224|Proteobacteria	1224|Proteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1724773_1	715451.ambt_10540	0.000205	49.7	COG1215@1|root,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria,1T3H7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.122	ko:K21366	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
k59_985061_1	929558.SMGD1_1581	2.73e-92	289.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_312612_1	1123518.ARWI01000001_gene2329	8.17e-215	616.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,45ZRS@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM nitrite reductase NAD(P)H , large subunit	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_1613195_1	929558.SMGD1_2313	1.05e-103	318.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_1613205_1	1453500.AT05_08730	2.06e-07	52.8	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
k59_1613205_2	1218173.BALCAV_0214005	2.59e-23	95.1	COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,4HIH7@91061|Bacilli,1ZH7F@1386|Bacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	yybD	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_482558_1	1172190.M947_09040	8.4e-124	368.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1613206_2	931626.Awo_c33280	8.21e-23	99.8	COG4335@1|root,COG4335@2|Bacteria,1TRE4@1239|Firmicutes,24A2G@186801|Clostridia,25Z05@186806|Eubacteriaceae	186801|Clostridia	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k59_1330635_1	1123518.ARWI01000001_gene1403	3.95e-67	223.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,45ZUR@72273|Thiotrichales	72273|Thiotrichales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1330635_2	90814.KL370892_gene2284	7.55e-63	210.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,1T1PC@1236|Gammaproteobacteria,461M2@72273|Thiotrichales	72273|Thiotrichales	EGP	Major Facilitator Superfamily	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	MFS_1
k59_932718_1	1121912.AUHD01000001_gene2814	5.55e-192	545.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HZJ8@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1180216_1	1120953.AUBH01000011_gene466	9.39e-19	90.5	COG2273@1|root,COG2273@2|Bacteria,1RANY@1224|Proteobacteria,1S0PJ@1236|Gammaproteobacteria,464UH@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1689718_1	313596.RB2501_04855	1.06e-22	96.7	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HYU1@117743|Flavobacteriia	976|Bacteroidetes	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_1689718_2	1121935.AQXX01000123_gene271	1e-22	92.8	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria,1XK54@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_48271_1	326298.Suden_1106	6.77e-98	291.0	COG3852@1|root,COG3852@2|Bacteria,1QAGK@1224|Proteobacteria,42RSW@68525|delta/epsilon subdivisions,2YPDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1225985_1	90814.KL370891_gene1567	2.6e-160	455.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,4603X@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_1689745_1	323850.Shew_1185	3.83e-111	329.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,2Q8NW@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081	SHMT
k59_613288_1	563040.Saut_0872	5.14e-42	148.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_613288_2	929558.SMGD1_2301	1.62e-67	212.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_950368_1	1178825.ALIH01000001_gene2500	8.21e-121	352.0	COG1577@1|root,COG1577@2|Bacteria,4NDYJ@976|Bacteroidetes,1HX9R@117743|Flavobacteriia	976|Bacteroidetes	I	mevalonate kinase	mvaK	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_950368_2	983544.Lacal_0660	6.1e-66	211.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes,1HY6U@117743|Flavobacteriia	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_1293449_1	1168067.JAGP01000001_gene932	9.04e-65	208.0	COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,1S2QK@1236|Gammaproteobacteria,462Y7@72273|Thiotrichales	72273|Thiotrichales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
k59_673380_1	90814.KL370891_gene1435	6.35e-58	192.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,45ZUG@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_557628_1	387093.SUN_0559	1.33e-85	282.0	COG3439@1|root,COG3439@2|Bacteria,1PWY7@1224|Proteobacteria,42Y9J@68525|delta/epsilon subdivisions,2YRF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_557628_2	929558.SMGD1_1065	3.29e-46	158.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,42SX1@68525|delta/epsilon subdivisions,2YPG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_897192_1	398579.Spea_3066	2.97e-102	303.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,2QAX8@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
k59_503340_1	563040.Saut_1466	7.42e-40	139.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2YN3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_503340_2	563040.Saut_1467	1.9e-36	127.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2YPDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GatB Yqey family protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_162657_1	411154.GFO_2112	9.68e-133	392.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1HXF9@117743|Flavobacteriia	976|Bacteroidetes	E	acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_221133_1	745718.JADT01000013_gene1369	1.52e-99	307.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_839963_1	90814.KL370891_gene856	1.17e-152	436.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,45ZMY@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1226044_1	929558.SMGD1_1107	2.99e-79	261.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2YNKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1352431_1	485918.Cpin_7153	3.33e-75	240.0	COG1595@1|root,COG1595@2|Bacteria,4NHIK@976|Bacteroidetes,1IVIJ@117747|Sphingobacteriia	976|Bacteroidetes	K	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_cc,Laminin_G_3
k59_1352431_2	760192.Halhy_4822	9.14e-16	80.1	COG0702@1|root,COG0702@2|Bacteria,4PKHQ@976|Bacteroidetes,1IQ8Z@117747|Sphingobacteriia	976|Bacteroidetes	GM	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1803456_1	929558.SMGD1_1919	3.07e-60	205.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
k59_334281_1	880073.Calab_2440	2.12e-10	64.7	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_613344_1	1190606.AJYG01000088_gene3560	1.4e-45	158.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,1XW78@135623|Vibrionales	135623|Vibrionales	P	Phosphate ABC transporter, periplasmic phosphate-binding protein PstS	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_389261_1	387093.SUN_0898	5.77e-24	92.4	2AMA7@1|root,31C55@2|Bacteria,1QGIU@1224|Proteobacteria,432YR@68525|delta/epsilon subdivisions,2YSPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_389261_2	563040.Saut_1290	5.15e-61	194.0	COG1633@1|root,COG1633@2|Bacteria,1Q0JN@1224|Proteobacteria,42S76@68525|delta/epsilon subdivisions,2YP4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_275706_1	929558.SMGD1_2276	1.65e-69	220.0	COG0810@1|root,COG0810@2|Bacteria,1QAAM@1224|Proteobacteria,42X9R@68525|delta/epsilon subdivisions,2YQQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
k59_673453_1	709032.Sulku_1049	3.84e-143	438.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_162721_1	929558.SMGD1_0707	8.41e-97	305.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_897271_1	323850.Shew_3580	4.26e-86	267.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,2Q9CV@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	2.7.7.6	ko:K00960,ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_389304_1	572480.Arnit_0414	8.47e-118	348.0	29W5U@1|root,30HQY@2|Bacteria,1QUJN@1224|Proteobacteria,42NUV@68525|delta/epsilon subdivisions,2YNFP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1461436_1	929558.SMGD1_2297	4.97e-55	180.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_1461452_1	326298.Suden_0437	6.42e-95	297.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2YMHD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_221222_2	1028806.GGE_0532	3.89e-21	94.4	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ52@1236|Gammaproteobacteria,1Y786@135625|Pasteurellales	135625|Pasteurellales	C	Cytochrome c-type	torC	-	-	ko:K03532	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Cytochrom_NNT
k59_334362_1	641526.ADIWIN_3313	2.9e-11	62.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1I1E3@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_334362_2	641526.ADIWIN_3310	3.78e-55	196.0	COG1345@1|root,COG2356@1|root,COG3227@1|root,COG3250@1|root,COG4886@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG3227@2|Bacteria,COG3250@2|Bacteria,COG4886@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LTD
k59_1803547_1	1123054.KB907703_gene1390	1.49e-30	118.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,1SZPF@1236|Gammaproteobacteria,1X2KG@135613|Chromatiales	135613|Chromatiales	S	Membrane transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Mem_trans
k59_1803547_2	326298.Suden_2043	3.35e-19	87.4	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2YMC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1352532_1	1137281.D778_01638	4.09e-89	268.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_1066018_1	411154.GFO_0079	4.35e-99	289.0	COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,1I3ED@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
k59_389357_1	257314.LJ_0012	1.02e-12	73.2	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_613454_1	572480.Arnit_3110	5.9e-103	314.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_48473_1	504487.JCM19302_1825	4.3e-48	158.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1523828_1	1123518.ARWI01000001_gene829	2.44e-114	336.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,45ZSJ@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_787965_1	1197477.IA57_01060	6.54e-182	541.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_842577_1	1038860.AXAP01000053_gene7255	8.75e-35	135.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JT1B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	MA20_03720	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_4,PAS_7,PAS_8,PAS_9
k59_1296207_1	1122176.KB903546_gene1036	1.74e-116	349.0	28JIH@1|root,2Z9BT@2|Bacteria,4NIF7@976|Bacteroidetes,1IU4X@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
k59_448595_1	1402135.SUH3_03245	7.43e-50	172.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2TQJM@28211|Alphaproteobacteria,3ZW22@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_223587_1	1380600.AUYN01000006_gene702	8.32e-41	149.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1HWZI@117743|Flavobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_391912_1	497321.C664_19036	8.7e-73	231.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VHZA@28216|Betaproteobacteria,2KURG@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the binding-protein-dependent transport system permease family	urtC	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_1068479_2	1123514.KB905899_gene1605	7.05e-79	241.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,4616P@72273|Thiotrichales	72273|Thiotrichales	Q	toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_1068479_3	1123518.ARWI01000001_gene811	8.35e-69	212.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,460SM@72273|Thiotrichales	72273|Thiotrichales	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1068479_4	1123518.ARWI01000001_gene812	1.56e-54	177.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_391922_1	945713.IALB_0115	8.62e-74	227.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	ywrF	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_391922_2	1449126.JQKL01000015_gene2931	2.2e-07	49.7	COG0041@1|root,COG0041@2|Bacteria	2|Bacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_223604_1	411154.GFO_0299	7.7e-37	131.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,1HZ9G@117743|Flavobacteriia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
k59_223604_2	1121931.AUHG01000018_gene1382	1.4e-51	179.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1HYT4@117743|Flavobacteriia	976|Bacteroidetes	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
k59_391925_1	498211.CJA_0127	6.15e-05	52.8	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
k59_1296242_1	1380600.AUYN01000009_gene1467	6.42e-92	276.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1HXXI@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1296242_2	1137281.D778_02499	6.25e-93	275.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1I0RX@117743|Flavobacteriia	976|Bacteroidetes	M	serine threonine protein kinase	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
k59_1009185_1	1565129.JSFF01000008_gene2632	1.5e-117	350.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,2QB24@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etfD	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,FAD_binding_3,NAD_binding_8
k59_1523878_1	1178825.ALIH01000013_gene498	1.14e-51	176.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1HXA7@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1523878_2	1380600.AUYN01000006_gene797	1.36e-143	409.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_952592_1	317025.Tcr_1543	1.97e-105	324.0	COG1262@1|root,COG2227@1|root,COG1262@2|Bacteria,COG2227@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,45ZXU@72273|Thiotrichales	72273|Thiotrichales	NT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
k59_1406497_1	1353528.DT23_04730	3.18e-28	112.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,2XMY6@285107|Thioclava	28211|Alphaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1406497_2	1353528.DT23_04735	1.41e-34	129.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2XN5D@285107|Thioclava	28211|Alphaproteobacteria	G	Alpha-amylase domain	aglA2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
k59_1464033_1	709032.Sulku_1529	1.35e-58	184.0	COG1145@1|root,COG1145@2|Bacteria,1Q4YJ@1224|Proteobacteria,4305G@68525|delta/epsilon subdivisions,2YRVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_1464033_2	338963.Pcar_2101	4.49e-13	67.4	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,42TMX@68525|delta/epsilon subdivisions,2WQJX@28221|Deltaproteobacteria,43SPY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_1228730_1	1197477.IA57_10040	8.57e-197	553.0	COG1730@1|root,COG1730@2|Bacteria,4NHZT@976|Bacteroidetes,1HZM3@117743|Flavobacteriia	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_448645_1	563040.Saut_1209	1.36e-33	119.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2YP8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_899944_1	318167.Sfri_3784	1.75e-142	412.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2Q8PV@267890|Shewanellaceae	1236|Gammaproteobacteria	U	type II secretion system protein	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_676096_1	945713.IALB_0846	2.46e-49	180.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Malectin,fn3
k59_1749446_2	1178825.ALIH01000003_gene2054	1.28e-228	643.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
k59_676114_1	749222.Nitsa_1035	2.99e-12	71.6	COG1196@1|root,COG2885@1|root,COG1196@2|Bacteria,COG2885@2|Bacteria,1N68I@1224|Proteobacteria,43BAI@68525|delta/epsilon subdivisions,2YT7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_676131_2	376686.Fjoh_5039	1.47e-158	454.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia,2NT12@237|Flavobacterium	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k59_1183112_1	225849.swp_4245	4.39e-107	318.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,2QAUI@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_4967,iYL1228.KPN_03375	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_111419_1	1117319.PSPO_13182	0.000277	44.3	2AW97@1|root,31N4I@2|Bacteria,1N1Z7@1224|Proteobacteria,1S7B9@1236|Gammaproteobacteria,2Q2QS@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111419_2	553385.JEMF01000018_gene846	3.6e-25	94.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XMCR@135619|Oceanospirillales	135619|Oceanospirillales	J	there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_111419_3	1288826.MSNKSG1_12702	2.69e-17	74.3	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,467R5@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_337045_1	572480.Arnit_0706	4.47e-49	165.0	29CAW@1|root,2ZZ9C@2|Bacteria,1Q5FH@1224|Proteobacteria,42Q2S@68525|delta/epsilon subdivisions,2YP18@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_337045_2	572480.Arnit_0707	4.11e-53	174.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1762971_2	1484460.JSWG01000005_gene2691	6.66e-10	57.8	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_1649869_1	313596.RB2501_12147	3.94e-15	72.8	2E3AK@1|root,32YEV@2|Bacteria,4P2VE@976|Bacteroidetes,1I8NP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1649869_2	1223410.KN050846_gene72	3.16e-63	198.0	2DNBA@1|root,32WJE@2|Bacteria,4NUM3@976|Bacteroidetes,1I4CD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_463987_1	563040.Saut_0536	4.46e-61	202.0	COG4773@1|root,COG4773@2|Bacteria,1QZMX@1224|Proteobacteria,42SA0@68525|delta/epsilon subdivisions,2YPCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_690144_1	1123518.ARWI01000001_gene450	1.49e-240	674.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,45ZPN@72273|Thiotrichales	72273|Thiotrichales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_1649872_1	563040.Saut_0391	2.05e-52	174.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_1649872_2	1537917.JU82_01595	1.49e-22	95.5	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2YMJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1311403_1	644076.SCH4B_4328	3.34e-25	103.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,4NBJS@97050|Ruegeria	28211|Alphaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1311403_2	1035839.AFNK01000006_gene1937	4.99e-25	103.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1Y71E@135625|Pasteurellales	135625|Pasteurellales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	ASCH,Methyltransf_31
k59_124223_1	1469557.JSWF01000014_gene2652	4.58e-70	232.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_124223_2	391596.PBAL39_20750	1.65e-17	79.3	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1INQS@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_576549_1	1484460.JSWG01000006_gene2758	3.26e-37	137.0	COG1538@1|root,COG1538@2|Bacteria,4NE4S@976|Bacteroidetes,1HXG4@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_633133_1	945543.VIBR0546_16823	6.94e-34	132.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1Y2H6@135623|Vibrionales	135623|Vibrionales	M	COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
k59_1140587_1	323850.Shew_1868	1.56e-54	186.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,2Q8I0@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k59_1083914_1	34506.g2513	2.97e-47	170.0	COG1219@1|root,KOG0745@2759|Eukaryota,39XQQ@33154|Opisthokonta,3BMR9@33208|Metazoa,3DFBN@33213|Bilateria	33208|Metazoa	O	ATP-dependent protease ATPase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_1083914_2	243365.CV_2528	2.45e-06	48.1	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,2KQ16@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_1311420_1	391603.FBALC1_14042	3.31e-119	356.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
k59_294062_1	323850.Shew_2971	1.41e-68	209.0	2AIIQ@1|root,3190S@2|Bacteria,1RHWT@1224|Proteobacteria,1S774@1236|Gammaproteobacteria,2QBY0@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SMI1-KNR4 cell-wall	IV02_22940	-	-	-	-	-	-	-	-	-	-	-	SUKH_5
k59_1480213_1	1178825.ALIH01000011_gene23	5.93e-86	271.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1253771_1	1353528.DT23_09750	3.94e-141	414.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,2XKK8@285107|Thioclava	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2
k59_1480214_1	90814.KL370891_gene1472	6.93e-27	105.0	COG1639@1|root,COG1639@2|Bacteria,1N6RT@1224|Proteobacteria,1SC8B@1236|Gammaproteobacteria,461BN@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1480214_2	1123518.ARWI01000001_gene2183	1.74e-45	162.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T239@1236|Gammaproteobacteria,461MW@72273|Thiotrichales	72273|Thiotrichales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1480217_1	522306.CAP2UW1_1944	7.95e-65	201.0	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2VRW2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_1480217_2	1157708.KB907450_gene5144	5.46e-12	65.5	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2VJ5B@28216|Betaproteobacteria,4AC0Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_1083929_1	929558.SMGD1_2632	7.3e-109	330.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_181584_1	318167.Sfri_3933	1.1e-47	161.0	2EMFU@1|root,33F4J@2|Bacteria,1NJZU@1224|Proteobacteria,1SJCR@1236|Gammaproteobacteria,2QAVD@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
k59_181585_1	411154.GFO_2884	7.9e-99	296.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1HXFU@117743|Flavobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_464028_1	1237149.C900_01613	3.11e-63	196.0	COG0784@1|root,COG0784@2|Bacteria,4NQW4@976|Bacteroidetes,47Q9X@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1649914_1	1121931.AUHG01000012_gene2902	2.88e-49	164.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,1I2IF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
k59_1649914_2	411154.GFO_1003	5.24e-63	200.0	COG1377@1|root,COG1377@2|Bacteria,4NMN3@976|Bacteroidetes,1I174@117743|Flavobacteriia	976|Bacteroidetes	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1083931_2	1123518.ARWI01000001_gene1854	2.13e-208	581.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,4600A@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1481798_1	1353276.JADR01000003_gene2681	7.04e-119	369.0	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_634759_1	563040.Saut_0628	2.6e-83	253.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_69994_1	1168067.JAGP01000001_gene584	2.84e-101	325.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,461VE@72273|Thiotrichales	72273|Thiotrichales	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1764581_1	1191523.MROS_2287	5.52e-61	200.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
k59_804218_1	1137281.D778_00901	7.08e-85	254.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1HY82@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
k59_804218_2	1137281.D778_00903	3.55e-21	89.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1I176@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1313029_1	980584.AFPB01000087_gene222	5.66e-49	166.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1HYEP@117743|Flavobacteriia,406XE@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
k59_12523_1	641526.ADIWIN_1298	4.01e-102	317.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
k59_747099_1	391616.OA238_c48170	4.74e-14	75.1	COG0582@1|root,COG0582@2|Bacteria,1PTZ1@1224|Proteobacteria,2U1YG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1537515_1	458817.Shal_3912	5.61e-76	233.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,2Q8TJ@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_4494	DAP_epimerase
k59_1537515_2	1336233.JAEH01000053_gene4115	2.39e-42	149.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,2QA3X@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_295594_1	1121918.ARWE01000001_gene896	7.44e-170	482.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,43SA1@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_971520_1	90814.KL370891_gene1012	3.1e-206	578.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,46066@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_1313056_1	1121912.AUHD01000017_gene3493	1.59e-199	564.0	COG4584@1|root,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,1HYXS@117743|Flavobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_1764628_1	983544.Lacal_1614	7.16e-40	142.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia	976|Bacteroidetes	I	dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_1764628_2	1484460.JSWG01000016_gene1629	5.63e-40	140.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_916570_1	5693.XP_814030.1	1.86e-13	69.7	COG0605@1|root,KOG0876@2759|Eukaryota,3XT4K@5653|Kinetoplastida	5653|Kinetoplastida	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	SODB1	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_916570_2	1165841.SULAR_03003	2.22e-26	107.0	COG0674@1|root,COG1014@1|root,COG4892@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,COG4892@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2YRFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Cyt-b5,POR,POR_N
k59_183177_1	1121012.AUKX01000003_gene1534	2.44e-226	647.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia,23GAX@178469|Arenibacter	976|Bacteroidetes	P	E1-E2 ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_634818_1	1178825.ALIH01000006_gene1475	1.77e-80	268.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SprB
k59_804266_1	745718.JADT01000004_gene1245	1.19e-67	221.0	COG3468@1|root,COG3468@2|Bacteria,4NEVR@976|Bacteroidetes,1HXUP@117743|Flavobacteriia	976|Bacteroidetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
k59_408626_1	572480.Arnit_0713	5.63e-47	152.0	COG3118@1|root,COG3118@2|Bacteria,1RE5A@1224|Proteobacteria,42W5C@68525|delta/epsilon subdivisions,2YQBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_408626_2	572480.Arnit_0712	1.03e-64	214.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,42P6Y@68525|delta/epsilon subdivisions,2YMZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_70064_1	391603.FBALC1_15407	1.54e-12	67.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_70064_2	1380600.AUYN01000007_gene3402	6.42e-59	195.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1313076_1	313598.MED152_05190	4.82e-21	91.3	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IEKJ@117743|Flavobacteriia,3VX1U@52959|Polaribacter	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_1313076_2	926562.Oweho_1699	6.49e-279	795.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1HY4T@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_465542_1	1565129.JSFF01000019_gene1711	1.98e-54	177.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,2Q9P6@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM inositol monophosphatase	cysQ	GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313	Inositol_P
k59_691859_1	929558.SMGD1_2790	2.2e-90	279.0	COG3400@1|root,COG3400@2|Bacteria,1N5T1@1224|Proteobacteria,42M0B@68525|delta/epsilon subdivisions,2YMCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain protein	-	-	-	ko:K09944	-	-	-	-	ko00000	-	-	-	TrkA_C
k59_125801_1	926549.KI421517_gene3163	2.37e-34	134.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,47JIP@768503|Cytophagia	976|Bacteroidetes	P	PFAM Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1195639_1	326298.Suden_1371	1.58e-110	331.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2YMW9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_971557_1	1230343.CANP01000010_gene1016	2.58e-26	96.7	2DP8N@1|root,3311E@2|Bacteria,1NC4X@1224|Proteobacteria,1SECM@1236|Gammaproteobacteria,1JF7C@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_971557_2	90814.KL370891_gene1628	3.68e-42	153.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,460IE@72273|Thiotrichales	72273|Thiotrichales	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_1085423_1	1232410.KI421417_gene2746	1.79e-102	323.0	COG0439@1|root,COG0511@1|root,COG0439@2|Bacteria,COG0511@2|Bacteria,1N71M@1224|Proteobacteria,42YTA@68525|delta/epsilon subdivisions,2WU1N@28221|Deltaproteobacteria,43TAW@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_1029958_1	762376.AXYL_05687	5.95e-33	131.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,3T655@506|Alcaligenaceae	28216|Betaproteobacteria	O	COG0542 ATPases with chaperone activity, ATP-binding subunit	clpV	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1481897_1	504487.JCM19302_513	1.91e-146	421.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1HXG5@117743|Flavobacteriia	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_1424960_1	1121931.AUHG01000020_gene3168	1.1e-89	266.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1HYRJ@117743|Flavobacteriia	976|Bacteroidetes	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
k59_1424960_2	1121931.AUHG01000020_gene3169	1.98e-47	154.0	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,1I2TK@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
k59_634850_1	1380600.AUYN01000001_gene2236	3.39e-114	330.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1HXYC@117743|Flavobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_634850_2	1380600.AUYN01000001_gene2235	3.84e-120	347.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1HWQ2@117743|Flavobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_351409_1	411154.GFO_0181	2.11e-90	268.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_1085426_1	1178825.ALIH01000005_gene143	2.43e-283	777.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1HZCP@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_1085426_2	1380600.AUYN01000009_gene2027	1.62e-42	142.0	2DMKZ@1|root,32SAQ@2|Bacteria,4NS7K@976|Bacteroidetes,1I49R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MpPF26
k59_1764695_1	323850.Shew_1359	1.8e-97	297.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,2QA42@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1708008_1	411154.GFO_2499	2.86e-35	130.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_1708008_2	1121931.AUHG01000011_gene1956	1.25e-67	213.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1HWT4@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
k59_1367864_2	76114.ebA6102	1.05e-62	206.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,2KU7H@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k59_691910_1	748247.AZKH_1445	3.32e-98	302.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,2KUBK@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_465588_1	317025.Tcr_2037	3.65e-139	407.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,463UV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1708030_1	572480.Arnit_1921	0.000199	42.7	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2YMT1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1708030_2	572480.Arnit_1922	9.11e-157	445.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_916648_1	1484460.JSWG01000015_gene968	5.44e-121	362.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1HXUQ@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1367877_1	1250232.JQNJ01000001_gene2485	1.49e-205	593.0	2C0EP@1|root,33T39@2|Bacteria,4P064@976|Bacteroidetes,1I8AP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239716_1	411154.GFO_3293	1.09e-162	468.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia	976|Bacteroidetes	M	Lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_578350_1	1123514.KB905903_gene403	4.32e-11	59.7	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,461GP@72273|Thiotrichales	72273|Thiotrichales	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k59_578350_2	90814.KL370891_gene1827	1.72e-77	243.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,4613Q@72273|Thiotrichales	72273|Thiotrichales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
k59_183279_1	411154.GFO_0101	9.36e-97	285.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia	976|Bacteroidetes	S	zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
k59_183279_2	1249975.JQLP01000005_gene2670	1.02e-46	152.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1HYHU@117743|Flavobacteriia,2P6GV@244698|Gillisia	976|Bacteroidetes	K	helix_turn_helix ASNC type	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_860230_1	1122179.KB890469_gene601	4.12e-89	278.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_1595471_1	1123518.ARWI01000001_gene772	1.74e-123	373.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,460B9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_691946_1	1121931.AUHG01000012_gene2941	2.75e-31	117.0	COG1294@1|root,COG1294@2|Bacteria,4NH9P@976|Bacteroidetes,1HXNH@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_1552250_1	631362.Thi970DRAFT_02566	4.36e-83	259.0	COG4310@1|root,COG4310@2|Bacteria,1NDWT@1224|Proteobacteria,1RRQM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
k59_820242_1	305700.B447_05258	1.63e-77	243.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_983372_1	1172190.M947_04270	4.75e-39	139.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_983372_2	1172190.M947_04280	2.32e-64	202.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42PQP@68525|delta/epsilon subdivisions,2YNQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	abc transporter atp-binding protein	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1044913_1	1166016.W5S_1834	2.39e-83	259.0	COG0338@1|root,COG0338@2|Bacteria,1NTIK@1224|Proteobacteria,1RSG6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Pfam D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k59_1044913_2	925775.XVE_4960	1.73e-58	201.0	COG1475@1|root,COG1475@2|Bacteria,1REBY@1224|Proteobacteria,1T0KK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1723163_1	1121931.AUHG01000010_gene77	5.73e-139	407.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_27040_1	998674.ATTE01000001_gene2967	7.02e-86	263.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,45ZNB@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k59_27040_2	1123518.ARWI01000001_gene479	3.79e-52	173.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria,461K5@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
k59_423791_1	985255.APHJ01000030_gene2484	1.96e-74	241.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.80,3.4.24.40	ko:K01406,ko:K03332	ko00051,ko01503,map00051,map01503	-	R00879	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_6,F5_F8_type_C,FIVAR,He_PIG,LVIVD,Laminin_G_3,SLH,TSP_3
k59_1439548_1	1565129.JSFF01000011_gene1917	1.11e-63	202.0	COG3147@1|root,COG3147@2|Bacteria,1MXHQ@1224|Proteobacteria,1RRKM@1236|Gammaproteobacteria,2QC32@267890|Shewanellaceae	1236|Gammaproteobacteria	D	PFAM Sporulation domain protein	dedD	GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k59_1439548_2	637905.SVI_2876	3.49e-09	57.4	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,2QAVQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_1997,iSDY_1059.SDY_2514	Mur_ligase_C,Mur_ligase_M
k59_1782337_1	1121899.Q764_03665	5.13e-46	153.0	COG3295@1|root,COG3295@2|Bacteria,4NNGT@976|Bacteroidetes,1I36S@117743|Flavobacteriia,2NT6S@237|Flavobacterium	976|Bacteroidetes	S	Putative PepSY_TM-like	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
k59_1782337_2	391603.FBALC1_12397	7.51e-55	206.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
k59_1441338_1	1121931.AUHG01000011_gene2370	2.42e-147	426.0	2C95T@1|root,2Z7NG@2|Bacteria,4NGVW@976|Bacteroidetes,1HZNE@117743|Flavobacteriia	976|Bacteroidetes	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
k59_368161_1	326298.Suden_0354	2.88e-156	479.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_368179_1	929558.SMGD1_1450	1.7e-09	56.2	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2YRU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YaeQ	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k59_368179_2	326298.Suden_1934	8.95e-55	172.0	COG3668@1|root,COG3668@2|Bacteria,1N8DJ@1224|Proteobacteria,42VZU@68525|delta/epsilon subdivisions,2YS5K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_87169_1	1121931.AUHG01000018_gene1405	1e-73	223.0	COG3871@1|root,COG3871@2|Bacteria,4NNGC@976|Bacteroidetes,1I1XY@117743|Flavobacteriia	976|Bacteroidetes	S	general stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
k59_1158954_1	1192124.LIG30_2471	1.79e-05	51.6	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,1K2KA@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Molybdenum cofactor synthesis domain protein	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1158954_2	314231.FP2506_02355	1.27e-06	54.7	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2TV2G@28211|Alphaproteobacteria,2PK61@255475|Aurantimonadaceae	28211|Alphaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_1330876_1	504487.JCM19302_2399	1.58e-82	275.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1725045_1	1380600.AUYN01000001_gene2902	7.18e-103	311.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_1441393_1	1123518.ARWI01000001_gene2204	1.3e-49	179.0	COG0840@1|root,COG0840@2|Bacteria,1NRAC@1224|Proteobacteria,1SKST@1236|Gammaproteobacteria,4624F@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_651942_1	641526.ADIWIN_2803	5.36e-44	148.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_651942_2	504487.JCM19302_4008	5.73e-52	179.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1HYRD@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_142450_2	945713.IALB_0711	1.88e-97	306.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing
k59_538559_1	929558.SMGD1_0924	3.36e-28	110.0	COG0265@1|root,COG0265@2|Bacteria,1QVTI@1224|Proteobacteria,42UMN@68525|delta/epsilon subdivisions,2YQ3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
k59_538559_2	1172190.M947_07170	4.48e-48	155.0	COG0718@1|root,COG0718@2|Bacteria,1Q3T8@1224|Proteobacteria,42UGW@68525|delta/epsilon subdivisions,2YPUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_538559_3	929558.SMGD1_0926	3.94e-76	228.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2YPGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_538559_4	563040.Saut_0298	1.86e-80	239.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,42SE0@68525|delta/epsilon subdivisions,2YPJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k59_257436_1	1005058.UMN179_00522	3.13e-117	359.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1YAG6@135625|Pasteurellales	135625|Pasteurellales	C	Aconitase C-terminal domain	-	-	4.2.1.117	ko:K20455	ko00640,map00640	-	R11263	RC01152	ko00000,ko00001,ko01000	-	-	-	Aconitase,Aconitase_C
k59_1499555_1	411154.GFO_0455	1.34e-60	197.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_87224_1	945713.IALB_0578	1.14e-64	210.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria	2|Bacteria	M	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
k59_1441444_1	1123228.AUIH01000006_gene2215	1.38e-74	227.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1XJJU@135619|Oceanospirillales	135619|Oceanospirillales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_763827_1	563040.Saut_1800	1.89e-70	224.0	COG4968@1|root,COG4968@2|Bacteria,1QUIY@1224|Proteobacteria,42S53@68525|delta/epsilon subdivisions,2YPC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_538596_1	929558.SMGD1_0807	1.41e-284	791.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2YMVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_538596_2	563040.Saut_1793	1.31e-21	94.7	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1046765_1	1172190.M947_04790	8.93e-142	412.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2YNE6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_1046765_2	1173027.Mic7113_3065	1.28e-44	152.0	COG3383@1|root,COG3383@2|Bacteria,1G3GD@1117|Cyanobacteria,1H7Z2@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	hoxU	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	iJN678.hoxU	Fer2_4,Fer4,Fer4_10,Fer4_6,NADH-G_4Fe-4S_3
k59_822349_1	1123514.KB905901_gene76	1.65e-79	248.0	COG4559@1|root,COG4559@2|Bacteria,1RD7N@1224|Proteobacteria,1RPUV@1236|Gammaproteobacteria,460RA@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system	hmuV	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_312958_1	388413.ALPR1_03680	2.95e-56	186.0	COG0548@1|root,COG0548@2|Bacteria,4NRY2@976|Bacteroidetes,47U2P@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	-	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1554214_1	1458462.JNLK01000001_gene1562	3.22e-52	189.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,27IXG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k59_1725141_1	1367491.BN865_10000	7.44e-13	68.6	COG1215@1|root,COG1215@2|Bacteria,1R5JQ@1224|Proteobacteria,43BVH@68525|delta/epsilon subdivisions,2YMCH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	hmm pf00535	pglI	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046527,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.293	ko:K17250	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_1725141_2	674977.VMC_14600	1.13e-62	209.0	2DXE7@1|root,344MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_257515_1	1123518.ARWI01000001_gene79	2.2e-142	405.0	293CN@1|root,2Z8R1@2|Bacteria,1R8CI@1224|Proteobacteria,1SC7G@1236|Gammaproteobacteria,462CU@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_257515_2	90813.JQMT01000001_gene886	1.68e-20	85.1	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,460RC@72273|Thiotrichales	72273|Thiotrichales	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_877459_1	443152.MDG893_20549	4.03e-25	114.0	COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_594676_1	1296415.JACC01000051_gene3721	1.46e-49	171.0	COG0438@1|root,COG0438@2|Bacteria,4NF7J@976|Bacteroidetes,1IIKH@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
k59_1272594_1	458817.Shal_1040	3.86e-57	199.0	COG1506@1|root,COG1506@2|Bacteria,1N75C@1224|Proteobacteria,1RXY1@1236|Gammaproteobacteria,2QAI9@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k59_1384692_1	1123514.KB905899_gene446	4.55e-93	288.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1S2RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_1554262_1	563040.Saut_0792	4.65e-60	197.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1554262_2	326298.Suden_0769	3.19e-30	111.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_368357_1	876044.IMCC3088_2266	1.68e-28	113.0	COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria,1J91Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	G-rich domain on putative tyrosine kinase	wzz	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_368357_2	90814.KL370891_gene424	7.89e-05	43.1	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k59_1725179_1	379066.GAU_3332	6.53e-21	95.5	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2,DDE_Tnp_1_4
k59_87333_1	1191523.MROS_2830	9.18e-90	286.0	COG5009@1|root,COG5009@2|Bacteria	2|Bacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_985512_1	755732.Fluta_0242	3.52e-92	279.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia,2PAHB@246874|Cryomorphaceae	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_257564_1	1123514.KB905899_gene1419	5.9e-84	261.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,460GT@72273|Thiotrichales	72273|Thiotrichales	N	SRP54-type protein, GTPase domain	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_822435_1	944547.ABLL_0732	2.99e-143	435.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_482949_2	1121035.AUCH01000003_gene1203	6.37e-35	126.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,2VR8U@28216|Betaproteobacteria,2KWCN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1499688_1	1178825.ALIH01000026_gene1863	1.1e-11	58.5	2EJFV@1|root,33D6V@2|Bacteria,4NYMX@976|Bacteroidetes,1I6TP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_985527_1	637905.SVI_0875	1.45e-122	370.0	COG2730@1|root,COG3291@1|root,COG2730@2|Bacteria,COG3291@2|Bacteria,1QUSE@1224|Proteobacteria,1T4XQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	CBD_II	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase
k59_1554296_1	572480.Arnit_0035	1.36e-118	363.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42PSD@68525|delta/epsilon subdivisions,2YNBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_BFD,NiFe_hyd_SSU_C,Oxidored_q6,Pyr_redox_2
k59_257584_1	326298.Suden_0566	9.86e-66	219.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1441585_1	1565129.JSFF01000001_gene755	6e-195	563.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,2Q8KU@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_482971_1	476272.RUMHYD_02687	1.4e-33	118.0	COG1143@1|root,COG1143@2|Bacteria,1VYIR@1239|Firmicutes,24PEQ@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_482971_2	457421.CBFG_02475	6.37e-12	67.8	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_985550_1	1123514.KB905899_gene1085	2.82e-42	143.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,46126@72273|Thiotrichales	72273|Thiotrichales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k59_985550_2	1123518.ARWI01000001_gene2457	4.32e-26	97.4	COG0607@1|root,COG0607@2|Bacteria,1NGN9@1224|Proteobacteria,1SIKU@1236|Gammaproteobacteria,462VD@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_538735_2	929558.SMGD1_0347	3.09e-99	291.0	COG1704@1|root,COG1704@2|Bacteria,1N0DU@1224|Proteobacteria,43B6Y@68525|delta/epsilon subdivisions,2YPB4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_538735_3	563040.Saut_0985	9.54e-39	144.0	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_1554320_1	1286093.C266_05769	2.02e-26	103.0	COG0765@1|root,COG0765@2|Bacteria,1RCKN@1224|Proteobacteria,2VQ2U@28216|Betaproteobacteria,1K7IY@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_1554320_2	1144342.PMI40_00571	2.91e-43	150.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VMMK@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
k59_1272685_1	1415778.JQMM01000001_gene1576	7.34e-60	191.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1J667@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3047 Outer membrane protein W	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_1384788_1	1250232.JQNJ01000001_gene1784	2.85e-32	124.0	COG4783@1|root,COG4783@2|Bacteria,4NPSA@976|Bacteroidetes,1I291@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_594775_1	945713.IALB_2053	6.21e-07	52.8	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_594775_2	485917.Phep_1484	3.23e-09	60.1	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_933124_1	985255.APHJ01000021_gene1299	6.48e-67	212.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia,2P5V4@244698|Gillisia	976|Bacteroidetes	C	Cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_933124_2	1121931.AUHG01000010_gene844	4.26e-68	207.0	COG5605@1|root,COG5605@2|Bacteria,4NTVI@976|Bacteroidetes,1IKX3@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
k59_1272711_1	926562.Oweho_1584	1.62e-27	110.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
k59_1686659_1	983544.Lacal_2581	4.06e-86	278.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_500293_1	1123367.C666_02910	6.28e-99	303.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,2KUXQ@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_670312_1	411154.GFO_1952	2.65e-146	433.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HY0G@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1401700_1	572480.Arnit_0895	8.96e-19	85.1	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1686694_1	1347342.BN863_5490	6.05e-39	139.0	290I6@1|root,2ZN71@2|Bacteria,4NM5S@976|Bacteroidetes,1I19E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_554572_1	279714.FuraDRAFT_2642	4.39e-07	53.1	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,2KPGY@206351|Neisseriales	206351|Neisseriales	O	cytochrome c-type biogenesis protein CcsB	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_554572_2	1123518.ARWI01000001_gene1441	1.4e-55	192.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein Ccs1 ResB	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_1458406_1	411154.GFO_1660	4.1e-72	229.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1HY14@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1458406_2	1121931.AUHG01000012_gene2520	1.08e-38	138.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia	976|Bacteroidetes	IQ	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
k59_1062997_1	1380600.AUYN01000009_gene1800	3.09e-83	255.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1062997_2	1178825.ALIH01000001_gene2674	3.04e-84	249.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1I1AD@117743|Flavobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_1062997_3	1121912.AUHD01000005_gene1800	5.55e-36	122.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_837768_1	1499686.BN1079_01362	2.96e-19	85.9	28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,1RNKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
k59_45486_1	1220582.RRU01S_10_01280	1.51e-71	230.0	28JCY@1|root,2Z97H@2|Bacteria,1N9GX@1224|Proteobacteria,2V27W@28211|Alphaproteobacteria,4BIVN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
k59_331054_1	1089550.ATTH01000001_gene1197	5.08e-39	145.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,4NDVH@976|Bacteroidetes,1FJQ2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	IrrE N-terminal-like domain	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_19,HTH_3,HTH_31,Peptidase_M78
k59_1349312_1	1122194.AUHU01000005_gene963	0.000322	44.7	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1T315@1236|Gammaproteobacteria,46AA9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,Pkinase
k59_1177234_1	693979.Bache_0396	1.78e-43	162.0	COG2385@1|root,COG4360@1|root,COG2385@2|Bacteria,COG4360@2|Bacteria,4NG21@976|Bacteroidetes,2FP4W@200643|Bacteroidia,4AM9T@815|Bacteroidaceae	976|Bacteroidetes	D	SpoIID LytB domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
k59_894370_1	709032.Sulku_2400	1.04e-85	259.0	COG1878@1|root,COG1878@2|Bacteria,1NG49@1224|Proteobacteria,42TCE@68525|delta/epsilon subdivisions,2YQ8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_894370_2	709032.Sulku_2401	1.44e-37	132.0	COG0546@1|root,COG0546@2|Bacteria,1N0R4@1224|Proteobacteria,42UH8@68525|delta/epsilon subdivisions,2YPXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_45532_1	1124780.ANNU01000002_gene1488	7.74e-53	177.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,47NU4@768503|Cytophagia	976|Bacteroidetes	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1003364_1	1121011.AUCB01000012_gene1703	5.38e-24	100.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia,23HT5@178469|Arenibacter	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1003364_2	1348583.ATLH01000001_gene3721	1.11e-104	317.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,1IJKN@117743|Flavobacteriia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_782192_1	945713.IALB_1389	2.79e-105	315.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_218333_1	572480.Arnit_2918	1.26e-19	88.2	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_218333_2	572480.Arnit_2917	3.92e-26	107.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2YQZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_4
k59_500432_1	326297.Sama_0614	1.37e-29	114.0	COG0668@1|root,COG0668@2|Bacteria,1MZKZ@1224|Proteobacteria,1S6N8@1236|Gammaproteobacteria,2QAKG@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_500432_2	944547.ABLL_2504	4.08e-44	146.0	COG5485@1|root,COG5485@2|Bacteria,1N1VS@1224|Proteobacteria,430HY@68525|delta/epsilon subdivisions,2YS0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
k59_1222848_1	90814.KL370891_gene1860	0.0	1092.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,45ZZS@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168,ko:K03451	-	-	-	-	ko00000,ko02000	2.A.15,2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_386133_1	572480.Arnit_1331	9e-83	268.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PilJ,SBP_bac_3,dCache_2,dCache_3
k59_1458496_1	1123518.ARWI01000001_gene729	8.46e-74	234.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,45ZYW@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_1458496_2	90814.KL370891_gene584	6.69e-25	102.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1800492_1	563040.Saut_1148	9.88e-15	70.1	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2YPEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_1800492_2	563040.Saut_1149	1.56e-113	328.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2YN3P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
k59_1800492_3	929558.SMGD1_2700	4.25e-13	66.6	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_554681_2	1004149.AFOE01000050_gene2595	2.63e-07	50.8	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_386152_1	1249480.B649_01210	5.95e-36	135.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_386152_2	572480.Arnit_2967	2.05e-46	162.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1800502_1	572480.Arnit_2637	1.9e-99	297.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_670469_1	948106.AWZT01000001_gene5052	5.35e-50	172.0	COG3307@1|root,COG3307@2|Bacteria,1R3TT@1224|Proteobacteria,2VYQK@28216|Betaproteobacteria,1K0WP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	TupA-like ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_TupA
k59_1571602_1	261292.Nit79A3_2536	1.52e-130	400.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1222897_1	1121931.AUHG01000012_gene2857	6.29e-184	533.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_1627873_2	1123326.JFBL01000002_gene1556	7.12e-42	148.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_782272_1	392500.Swoo_0285	9.86e-74	242.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,2Q9C2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_782272_2	1565129.JSFF01000013_gene343	0.000125	42.7	COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,2QAII@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Belongs to the Rsd AlgQ family	rsd	GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	ko:K07740	-	-	-	-	ko00000	-	-	-	Rsd_AlgQ
k59_837854_1	305700.B447_21277	6.04e-62	210.0	COG1587@1|root,COG2959@1|root,COG1587@2|Bacteria,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,2KW9U@206389|Rhodocyclales	206389|Rhodocyclales	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
k59_1458542_1	748247.AZKH_3838	7.13e-43	162.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_554725_1	1137281.D778_00401	3.11e-128	384.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1HYTZ@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_331203_1	572480.Arnit_2917	1.44e-83	267.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2YQZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_4
k59_1003471_1	572480.Arnit_2402	3.37e-142	414.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_331214_1	90813.JQMT01000001_gene1780	2.92e-78	239.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,1RQ9U@1236|Gammaproteobacteria,460HM@72273|Thiotrichales	72273|Thiotrichales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_837877_1	411154.GFO_2756	2.01e-98	312.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_947984_1	391587.KAOT1_18957	1.24e-156	482.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
k59_1222969_1	1278307.KB907000_gene333	2.98e-16	84.7	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1RWUI@1236|Gammaproteobacteria,2QJ5A@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1458587_1	572480.Arnit_1081	4.82e-99	310.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1MU9B@1224|Proteobacteria,42P4R@68525|delta/epsilon subdivisions,2YM92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k59_1177413_1	1123514.KB905900_gene2093	2.3e-196	564.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,45ZUX@72273|Thiotrichales	72273|Thiotrichales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_443235_1	563040.Saut_1469	3.51e-89	288.0	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1743753_1	1250006.JHZZ01000001_gene2222	8.33e-128	394.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,1HWMP@117743|Flavobacteriia,3VWZU@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_159819_1	1121878.AUGL01000008_gene1336	2.2e-12	66.6	28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3360
k59_159819_2	1117314.PCIT_09629	2.11e-05	48.1	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,2Q097@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG0514 Superfamily II DNA helicase	recQ1	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_554792_1	1122225.AULQ01000004_gene2130	1.31e-199	557.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia	976|Bacteroidetes	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_1290654_1	360104.CCC13826_0447	1.24e-29	122.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_218504_1	929558.SMGD1_1912	1.18e-88	281.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_1063249_1	1392490.JHZX01000001_gene1693	4.02e-15	70.1	2E7YU@1|root,332D8@2|Bacteria,4NV36@976|Bacteroidetes,1I6IZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_729151_1	90814.KL370891_gene216	8.21e-32	122.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,45ZYU@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_729151_2	1168067.JAGP01000001_gene235	2.75e-70	220.0	COG0500@1|root,COG0500@2|Bacteria,1QVWX@1224|Proteobacteria,1T2M6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1290672_1	1163408.UU9_14490	1.22e-10	69.3	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,1X5EV@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_1349550_1	1123035.ARLA01000023_gene1180	6.64e-08	54.3	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,1HXD0@117743|Flavobacteriia,4C2YB@83612|Psychroflexus	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_1349550_2	1121912.AUHD01000016_gene2945	4.4e-40	142.0	COG1216@1|root,COG1216@2|Bacteria,4NGD0@976|Bacteroidetes,1HYNU@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1349553_1	326298.Suden_2085	5.63e-107	320.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2YMJX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	ATP synthase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k59_554844_1	411154.GFO_3584	1.29e-169	482.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1800683_1	1168067.JAGP01000001_gene221	5.36e-154	434.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,46063@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_1800683_2	1123518.ARWI01000001_gene1071	4.63e-51	167.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,46180@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the PsiE family	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
k59_1800683_3	317025.Tcr_0262	7.4e-33	120.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,4607J@72273|Thiotrichales	72273|Thiotrichales	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_218566_1	90813.JQMT01000001_gene881	4.27e-108	341.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,4602H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_386361_1	439496.RBY4I_357	3.44e-18	81.6	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ubiquinol-cytochrome C reductase	MA20_25125	-	-	-	-	-	-	-	-	-	-	-	EVE
k59_782471_2	1237149.C900_04974	4.64e-58	182.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k59_1401984_1	1123228.AUIH01000004_gene1049	1.18e-76	256.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHSH@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_1351817_1	1123234.AUKI01000014_gene2440	2.45e-50	174.0	2C95T@1|root,2Z7NG@2|Bacteria,4NGVW@976|Bacteroidetes,1HZNE@117743|Flavobacteriia	976|Bacteroidetes	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
k59_557081_1	983544.Lacal_1042	1.02e-47	166.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,1HXBG@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
k59_1802865_1	1197477.IA57_03335	8.46e-99	287.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1I170@117743|Flavobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_1802867_2	575564.HMPREF0014_03410	4.41e-13	70.5	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,3NMFE@468|Moraxellaceae	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_1065401_1	1519464.HY22_13125	1.16e-06	49.7	COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
k59_1065401_2	1405.DJ92_4955	7.71e-30	117.0	COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,1ZEQ1@1386|Bacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_220634_1	563040.Saut_1930	2.39e-125	374.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2YM82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_333689_1	1348114.OM33_08015	6e-23	101.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,2Q0Z5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_672886_1	283942.IL1160	7.21e-56	195.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,2QFGF@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
k59_896665_1	1137281.D778_01631	0.0	1174.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1HYS9@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
k59_1419048_1	392500.Swoo_2498	8.68e-87	265.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,2Q9JE@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the citrate synthase family	prpC	GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	iECED1_1282.ECED1_0365,iECIAI1_1343.ECIAI1_0334,iECIAI39_1322.ECIAI39_0347,iECP_1309.ECP_0408,iECSF_1327.ECSF_0308,iEcE24377_1341.EcE24377A_0357,iJN746.PP_2335,iLF82_1304.LF82_1740,iNRG857_1313.NRG857_01630	Citrate_synt
k59_1419048_2	318167.Sfri_1857	4.08e-38	134.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,2Q8SB@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407	PEP_mutase
k59_741131_1	1122915.AUGY01000014_gene2726	4.2e-53	186.0	COG3437@1|root,COG3437@2|Bacteria,1UYCB@1239|Firmicutes,4HE6S@91061|Bacilli,2769T@186822|Paenibacillaceae	91061|Bacilli	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD
k59_1024012_1	1484460.JSWG01000001_gene2386	8.51e-95	280.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,1I1SZ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_1361862_1	1178825.ALIH01000006_gene1542	2.27e-143	411.0	COG0589@1|root,COG0589@2|Bacteria,4NE48@976|Bacteroidetes,1HXRC@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1361862_2	1317122.ATO12_08330	3.46e-47	156.0	2BK9M@1|root,32EPT@2|Bacteria,4NQGA@976|Bacteroidetes,1I2SP@117743|Flavobacteriia,2YJSD@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1191363_1	688270.Celal_1786	4.19e-114	332.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,1HXES@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1191363_2	1353276.JADR01000008_gene886	1.65e-125	373.0	COG1538@1|root,COG1538@2|Bacteria,4NKWK@976|Bacteroidetes,1I4KR@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_967151_1	1123354.AUDR01000015_gene459	3.48e-115	360.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2WGGY@28216|Betaproteobacteria,1KSCB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_119862_1	1298608.JCM18900_11086	1.95e-12	70.5	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,3NM70@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_119862_2	1121912.AUHD01000001_gene2690	9.74e-41	146.0	COG2979@1|root,COG2979@2|Bacteria,4PKCN@976|Bacteroidetes,1IJ7M@117743|Flavobacteriia	976|Bacteroidetes	S	LETM1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LETM1
k59_571894_1	1249997.JHZW01000002_gene249	7.24e-78	252.0	COG1524@1|root,COG1524@2|Bacteria,4NIUS@976|Bacteroidetes,1HZKJ@117743|Flavobacteriia,2PHA1@252356|Maribacter	976|Bacteroidetes	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
k59_1758363_1	743299.Acife_2094	1.83e-23	97.1	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,1S9ED@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1079491_1	1469557.JSWF01000035_gene1095	1.35e-68	223.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
k59_1645345_1	1565129.JSFF01000002_gene3445	1.17e-59	204.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,2QB36@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164	PBP1_TM,Transgly,Transpeptidase,UB2H
k59_1361878_2	572480.Arnit_2650	5.47e-154	447.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_853754_1	1380600.AUYN01000001_gene2779	1.4e-102	311.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1475379_1	1123514.KB905899_gene1989	3.48e-97	297.0	COG0531@1|root,COG0531@2|Bacteria,1PKIV@1224|Proteobacteria,1T9HU@1236|Gammaproteobacteria,461MJ@72273|Thiotrichales	72273|Thiotrichales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_1249162_1	491952.Mar181_0644	4.65e-16	84.7	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,1XRYP@135619|Oceanospirillales	135619|Oceanospirillales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_459298_1	641526.ADIWIN_1921	1.47e-65	209.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1HXFU@117743|Flavobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_459298_2	504487.JCM19302_1806	8.87e-107	311.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1HZK2@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
k59_459298_3	745718.JADT01000004_gene1245	2.28e-129	384.0	COG3468@1|root,COG3468@2|Bacteria,4NEVR@976|Bacteroidetes,1HXUP@117743|Flavobacteriia	976|Bacteroidetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
k59_685374_1	90813.JQMT01000001_gene689	3.06e-53	177.0	COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,1S4JR@1236|Gammaproteobacteria,461H1@72273|Thiotrichales	72273|Thiotrichales	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
k59_1024077_1	572480.Arnit_1810	4.24e-105	319.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2YMSG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.6,3.1.4.16	ko:K01119,ko:K17224	ko00230,ko00240,ko00920,ko01100,ko01120,map00230,map00240,map00920,map01100,map01120	M00595	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135,R10151	RC00078,RC00296,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_119904_1	317025.Tcr_1001	3.04e-116	357.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales	72273|Thiotrichales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1024088_1	653733.Selin_1952	4.73e-14	71.6	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
k59_1531736_1	411154.GFO_0654	7.72e-07	50.1	COG1215@1|root,COG1215@2|Bacteria,4PKBU@976|Bacteroidetes,1HXS3@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
k59_1531736_2	411154.GFO_0655	5.15e-145	415.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1I0BY@117743|Flavobacteriia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
k59_1645394_1	313598.MED152_10115	8.6e-68	216.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HWPQ@117743|Flavobacteriia,3VVHC@52959|Polaribacter	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1645394_2	1197477.IA57_03305	1.31e-61	189.0	COG0526@1|root,COG0526@2|Bacteria,4PKJW@976|Bacteroidetes,1IJB9@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1645394_3	1178825.ALIH01000003_gene2002	5.95e-17	77.8	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1249207_1	317025.Tcr_0519	2.57e-36	134.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,45ZS5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1249207_2	317025.Tcr_0520	1.56e-83	247.0	COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,1S41A@1236|Gammaproteobacteria,460WF@72273|Thiotrichales	72273|Thiotrichales	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
k59_1701731_1	929558.SMGD1_2440	1.73e-47	161.0	2AGMT@1|root,316V3@2|Bacteria,1PY20@1224|Proteobacteria,42NND@68525|delta/epsilon subdivisions,2YMQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	pgbB	-	-	-	-	-	-	-	-	-	-	-	PGBA_C,PQQ_2
k59_1701731_2	1172190.M947_00030	3.96e-22	92.8	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_6820_1	1121373.KB903623_gene2288	1.34e-49	179.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
k59_6820_2	468059.AUHA01000002_gene150	3.37e-07	57.4	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
k59_6820_3	1408813.AYMG01000020_gene3046	5.39e-26	113.0	COG1834@1|root,COG1834@2|Bacteria,4NE18@976|Bacteroidetes,1IPR8@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_515087_1	572480.Arnit_1427	5.45e-26	100.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2YMCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_515087_2	572480.Arnit_1426	1.55e-84	249.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2YP73@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_459309_19	317025.Tcr_0657	1.9e-42	147.0	COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,1SSUP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_459309_21	862965.PARA_01030	2.63e-167	471.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1Y6V3@135625|Pasteurellales	135625|Pasteurellales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_459309_22	1540098.A0A0A0RQJ2_9CAUD	8.74e-23	95.1	4QFW7@10239|Viruses,4QU0S@28883|Caudovirales,4QM9S@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6841_1	1469557.JSWF01000014_gene2652	2.6e-76	249.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_1760410_1	572480.Arnit_1948	2.58e-103	312.0	COG0457@1|root,COG0457@2|Bacteria,1MWHE@1224|Proteobacteria,42S1C@68525|delta/epsilon subdivisions,2YNIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_16
k59_291552_1	1123228.AUIH01000022_gene3112	4.29e-43	143.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1XKF8@135619|Oceanospirillales	135619|Oceanospirillales	S	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
k59_291552_2	440512.C211_09503	1.18e-67	220.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
k59_968609_1	1150621.SMUL_3193	5.98e-62	214.0	COG2604@1|root,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2YMMI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01973	pseE	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k59_404659_1	62928.azo1540	2.14e-70	221.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,2KXXF@206389|Rhodocyclales	206389|Rhodocyclales	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_687514_1	1122225.AULQ01000006_gene928	1.49e-80	249.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_855870_1	1500890.JQNL01000001_gene726	2.42e-13	71.2	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1X628@135614|Xanthomonadales	135614|Xanthomonadales	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
k59_1026161_1	326298.Suden_2031	0.0	1099.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2YMTE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1308890_1	879212.DespoDRAFT_02835	4.73e-117	359.0	COG4974@1|root,COG4974@2|Bacteria,1NRZQ@1224|Proteobacteria	1224|Proteobacteria	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_1138315_1	1121918.ARWE01000001_gene1243	2.39e-56	178.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,42UUN@68525|delta/epsilon subdivisions,2WPZH@28221|Deltaproteobacteria,43SMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_968623_1	709032.Sulku_1672	1.5e-51	175.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1PGQJ@1224|Proteobacteria,42TF5@68525|delta/epsilon subdivisions,2YTKE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,GGDEF,PAS_9
k59_968623_2	326298.Suden_0343	3.49e-50	166.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42R9F@68525|delta/epsilon subdivisions,2YNVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_404688_1	1123228.AUIH01000057_gene3714	1.22e-07	52.8	COG2175@1|root,COG2175@2|Bacteria,1MWQ6@1224|Proteobacteria,1RP8I@1236|Gammaproteobacteria,1XN93@135619|Oceanospirillales	135619|Oceanospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
k59_404688_2	1160137.KB907307_gene2761	1.08e-15	74.3	COG1694@1|root,COG1694@2|Bacteria,2GSAS@201174|Actinobacteria	201174|Actinobacteria	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG,MazG-like
k59_1251325_1	565045.NOR51B_1307	3.51e-13	66.2	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1J67T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_1251325_2	1123514.KB905899_gene1128	4.92e-125	369.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,460FC@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_461441_1	1537917.JU82_08725	1.79e-58	200.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_461441_2	929558.SMGD1_2297	1.9e-29	110.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_976621_1	1172190.M947_08990	2.85e-66	221.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_976621_2	1172190.M947_08980	1.4e-43	144.0	2BSRI@1|root,32MUE@2|Bacteria,1Q3E8@1224|Proteobacteria,42X6B@68525|delta/epsilon subdivisions,2YQST@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_976621_3	929558.SMGD1_0336	2.26e-83	258.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_698949_1	90814.KL370891_gene1808	8.93e-144	415.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4605P@72273|Thiotrichales	72273|Thiotrichales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_415396_1	1190606.AJYG01000018_gene3353	3.77e-13	69.7	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,1XWKM@135623|Vibrionales	135623|Vibrionales	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_415396_2	1123228.AUIH01000011_gene2126	5.92e-84	256.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,1XH8B@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_472611_1	62928.azo1977	1.57e-108	325.0	COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,2VKUF@28216|Betaproteobacteria,2KYME@206389|Rhodocyclales	206389|Rhodocyclales	P	Oxygenase component OxoO, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase protein. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation	-	-	-	-	-	-	-	-	-	-	-	-	Aromatic_hydrox,Rieske
k59_1715023_1	411154.GFO_0764	7.48e-140	398.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrophosphatase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
k59_976622_1	1249975.JQLP01000005_gene1432	7.84e-46	160.0	COG1538@1|root,COG1538@2|Bacteria,4NDZ6@976|Bacteroidetes,1HY4E@117743|Flavobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_976622_2	926559.JoomaDRAFT_2744	4.46e-143	416.0	COG1566@1|root,COG1566@2|Bacteria,4NEQJ@976|Bacteroidetes,1HYZU@117743|Flavobacteriia	976|Bacteroidetes	V	secretion protein HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_976622_3	1249975.JQLP01000005_gene1430	2.51e-175	501.0	COG0477@1|root,COG0477@2|Bacteria,4PKB1@976|Bacteroidetes,1HX4H@117743|Flavobacteriia	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_358010_1	411154.GFO_2773	2.17e-87	275.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1HXSX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_358010_2	411154.GFO_2772	1.09e-38	140.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_922980_1	1165096.ARWF01000001_gene2252	4.72e-50	172.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,2KKB0@206350|Nitrosomonadales	206350|Nitrosomonadales	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1431511_1	317025.Tcr_2036	4.66e-25	99.8	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,1S4H2@1236|Gammaproteobacteria,4638H@72273|Thiotrichales	72273|Thiotrichales	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_1431511_2	317025.Tcr_2035	1.63e-23	102.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,45ZRI@72273|Thiotrichales	72273|Thiotrichales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1092037_1	563040.Saut_1886	9.47e-48	169.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1092037_2	929558.SMGD1_1571	5.69e-67	207.0	COG5615@1|root,COG5615@2|Bacteria,1Q1KK@1224|Proteobacteria,42TX3@68525|delta/epsilon subdivisions,2YPV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1092037_3	563040.Saut_1884	3.06e-44	148.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2YP8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_867156_1	1236541.BALL01000006_gene1061	3.58e-73	235.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAC7@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
k59_18910_1	929558.SMGD1_0459	1.64e-105	333.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_18910_2	929558.SMGD1_0458	4.91e-47	159.0	COG3713@1|root,COG3713@2|Bacteria,1MWQN@1224|Proteobacteria,42W5N@68525|delta/epsilon subdivisions,2YQHA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k59_1715044_1	497321.C664_03240	6.55e-76	238.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,2KW07@206389|Rhodocyclales	206389|Rhodocyclales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_190087_1	1121931.AUHG01000011_gene2039	4.3e-30	118.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXPB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_190087_2	411154.GFO_2344	5.36e-84	254.0	28IV9@1|root,2Z8TQ@2|Bacteria,4NHX4@976|Bacteroidetes,1I101@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_753630_1	1121931.AUHG01000010_gene281	1.99e-82	251.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_472657_2	992406.RIA_0568	8.61e-10	60.1	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1I19U@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_77296_1	709032.Sulku_0175	1.05e-19	90.9	COG1450@1|root,COG1450@2|Bacteria,1N6HF@1224|Proteobacteria,42XAQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	NU	Belongs to the GSP D family	-	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	OmpA,Secretin
k59_1262390_1	1380600.AUYN01000001_gene2261	4.33e-127	371.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_77305_1	411154.GFO_0254	7.78e-168	493.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1036737_1	391603.FBALC1_07623	1.21e-103	316.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1431557_1	626887.J057_05961	9.39e-19	84.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,1RPI6@1236|Gammaproteobacteria,469ZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	non-haem dioxygenase in morphine synthesis N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_699031_2	1127692.HMPREF9075_01555	1.48e-19	88.6	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia,1EQH9@1016|Capnocytophaga	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_1771678_1	1380600.AUYN01000002_gene4	4.88e-56	196.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_1771678_2	1392489.JPOL01000001_gene3427	4.84e-50	179.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia,2XISK@283735|Leeuwenhoekiella	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_753676_1	1123514.KB905899_gene1061	9.81e-84	249.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,460XG@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0260 family	-	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_1431588_1	1237149.C900_04618	2.66e-66	213.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_1431588_2	313606.M23134_03406	4.35e-06	47.8	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
k59_1658544_1	1469557.JSWF01000046_gene185	1.3e-61	196.0	COG2608@1|root,COG2608@2|Bacteria,4NPHG@976|Bacteroidetes,1IJ2G@117743|Flavobacteriia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k59_1658544_2	983544.Lacal_1225	4.22e-84	254.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1I1EE@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
k59_1658544_3	1380600.AUYN01000006_gene598	1.37e-17	81.3	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_528360_1	504487.JCM19302_889	6.8e-92	270.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1HWUA@117743|Flavobacteriia	976|Bacteroidetes	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_528360_2	1336803.PHEL49_0618	3.71e-29	111.0	2DHQ2@1|root,32U9I@2|Bacteria,4NSQ5@976|Bacteroidetes,1I48C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_528360_3	313603.FB2170_11016	7.86e-116	335.0	28PW8@1|root,2ZCGN@2|Bacteria,4NMDI@976|Bacteroidetes,1I1TS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_528360_4	313603.FB2170_11021	4.34e-96	281.0	COG1595@1|root,COG1595@2|Bacteria,4NMPT@976|Bacteroidetes,1I2JJ@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_528360_5	1484460.JSWG01000012_gene1264	1.74e-42	139.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1I3W5@117743|Flavobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_528360_6	1122225.AULQ01000008_gene1201	2.04e-94	290.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1HY1F@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
k59_77368_1	929558.SMGD1_0536	4.02e-88	277.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2YTC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
k59_699085_1	388413.ALPR1_15834	1.95e-45	151.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes	976|Bacteroidetes	S	PFAM DsrE DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_132505_1	1178825.ALIH01000002_gene833	3.15e-80	255.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
k59_132505_2	1380600.AUYN01000001_gene2342	3.54e-34	130.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
k59_132505_3	1380600.AUYN01000001_gene2341	7.21e-20	86.3	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1771738_1	1121481.AUAS01000002_gene3230	1.47e-18	86.7	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1771738_2	504472.Slin_4594	7.61e-29	117.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1602615_1	317025.Tcr_0522	1.14e-136	395.0	COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,45ZNX@72273|Thiotrichales	72273|Thiotrichales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
k59_1602615_2	1123518.ARWI01000001_gene761	2.59e-92	273.0	COG1416@1|root,COG1416@2|Bacteria,1N0U1@1224|Proteobacteria,1SGKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_192406_1	1178825.ALIH01000002_gene1117	1.73e-08	57.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_192406_2	1121912.AUHD01000001_gene2888	2.81e-72	240.0	COG2197@1|root,COG3292@1|root,COG2197@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1660867_1	1355374.JARU01000011_gene2232	1.66e-74	244.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1NU9A@1224|Proteobacteria,42YSZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,dCache_2
k59_417912_1	1550091.JROE01000018_gene453	3.42e-07	57.8	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1IPV8@117747|Sphingobacteriia	976|Bacteroidetes	PT	COG3712 Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_417912_2	1453505.JASY01000019_gene4771	5.43e-63	200.0	COG1595@1|root,COG1595@2|Bacteria,4NQ2T@976|Bacteroidetes,1I399@117743|Flavobacteriia,2NV1B@237|Flavobacterium	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_417912_3	555500.I215_15462	1.21e-46	151.0	COG2963@1|root,COG2963@2|Bacteria,4NPG2@976|Bacteroidetes,1I2BD@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1
k59_869557_1	85643.Tmz1t_0171	2.65e-43	156.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,2KVSH@206389|Rhodocyclales	206389|Rhodocyclales	C	Isocitrate dehydrogenase	icd2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_79460_2	1380600.AUYN01000009_gene1582	4.21e-181	522.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_79460_3	1347342.BN863_26240	0.0	1089.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
k59_79460_4	1121011.AUCB01000046_gene688	1.12e-263	731.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia,23HSY@178469|Arenibacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_79460_5	1121912.AUHD01000009_gene3691	0.0	1008.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,PA14,Sulfatase
k59_360193_1	1236541.BALL01000012_gene1889	7.56e-25	97.8	COG1846@1|root,COG1846@2|Bacteria,1NA1D@1224|Proteobacteria,1SF3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_360193_2	709032.Sulku_1812	1.74e-23	96.3	COG0697@1|root,COG0697@2|Bacteria,1PIFB@1224|Proteobacteria,42QAN@68525|delta/epsilon subdivisions,2YNGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	integral membrane protein (DUF6 domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_869569_1	305700.B447_17973	1.8e-55	188.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KV5W@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_978347_1	1123518.ARWI01000001_gene1560	1.07e-63	204.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,4602Z@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_978347_2	90814.KL370892_gene2128	3.85e-40	137.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,460PM@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_134591_1	572480.Arnit_0521	5.46e-123	360.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2YNT6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1660916_1	572480.Arnit_2536	1.12e-84	273.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2YM9E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL,Patched
k59_530791_1	506534.Rhein_3598	2.25e-11	67.0	COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,1RY48@1236|Gammaproteobacteria,1WYSJ@135613|Chromatiales	135613|Chromatiales	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1717290_1	1123228.AUIH01000010_gene4043	1.56e-52	176.0	COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,1RN4E@1236|Gammaproteobacteria,1XJ2C@135619|Oceanospirillales	135619|Oceanospirillales	G	Functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis	malE	-	-	ko:K10108	ko02010,ko02030,map02010,map02030	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	SBP_bac_8
k59_644117_1	1123367.C666_00360	1.18e-76	229.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,2KWG3@206389|Rhodocyclales	206389|Rhodocyclales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_644117_2	887898.HMPREF0551_1882	7.65e-45	154.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,1K3PH@119060|Burkholderiaceae	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_249096_2	1123053.AUDG01000005_gene3944	1.7e-45	162.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_79496_1	1122194.AUHU01000010_gene3140	5.41e-107	336.0	COG1874@1|root,COG1874@2|Bacteria,1NDQP@1224|Proteobacteria,1SDV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-galactosidase	bga2	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,Glyco_hydro_35
k59_814172_1	1123518.ARWI01000001_gene286	8.5e-20	87.8	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales	72273|Thiotrichales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_814172_2	90814.KL370891_gene1003	1.39e-25	95.9	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,4611Y@72273|Thiotrichales	72273|Thiotrichales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_417948_1	1380600.AUYN01000001_gene2504	4.45e-41	145.0	2D1XX@1|root,32TBN@2|Bacteria,4NSEI@976|Bacteroidetes,1I4SM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_417948_2	1484460.JSWG01000015_gene1080	9.47e-58	182.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,1I3A8@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
k59_417948_3	1380600.AUYN01000001_gene2508	3.8e-73	229.0	2BTPY@1|root,32NX0@2|Bacteria,4NRTI@976|Bacteroidetes,1I36I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_644125_1	929558.SMGD1_2865	1.29e-55	174.0	COG2033@1|root,COG2033@2|Bacteria,1NDWH@1224|Proteobacteria,42RSM@68525|delta/epsilon subdivisions,2YP5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
k59_644125_2	572480.Arnit_1078	1.01e-152	433.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2YN0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS
k59_586981_1	1121931.AUHG01000018_gene1381	1.37e-93	282.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,1HX0X@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
k59_644136_1	572480.Arnit_0226	6.77e-97	285.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2YP6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0831	CoaE
k59_1150795_1	504487.JCM19302_809	4.88e-151	441.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_39326_1	411154.GFO_0328	9.71e-106	310.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1HX5W@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_378630_1	637905.SVI_0728	4.06e-34	127.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,1RR3P@1236|Gammaproteobacteria,2QAD6@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Component of the transport system for branched-chain amino acids	brnQ	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k59_378630_2	225849.swp_4230	4.27e-39	138.0	COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,2QBPT@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	yfiC	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
k59_1342011_1	411154.GFO_2064	3.41e-96	290.0	COG2197@1|root,COG2197@2|Bacteria,4NKCC@976|Bacteroidetes,1I0ID@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_547694_1	1172190.M947_04290	7.52e-21	99.8	COG0745@1|root,COG0745@2|Bacteria,1QXJT@1224|Proteobacteria,42V47@68525|delta/epsilon subdivisions,2YQ8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	ko:K07288	-	-	-	-	ko00000	-	-	-	-
k59_547694_2	1172190.M947_04295	4.06e-49	161.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
k59_1510726_1	504487.JCM19302_672	2.58e-75	226.0	COG3565@1|root,COG3565@2|Bacteria,4NNHW@976|Bacteroidetes,1I212@117743|Flavobacteriia	976|Bacteroidetes	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1510726_2	1178825.ALIH01000001_gene2636	2.21e-120	348.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,1HY0B@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1215395_1	1270193.JARP01000001_gene2446	2.49e-109	329.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2NSX1@237|Flavobacterium	976|Bacteroidetes	E	Asparagine synthetase B	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_941785_1	83406.HDN1F_25760	4.38e-27	104.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,1T20E@1236|Gammaproteobacteria,1J6P3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_547727_1	318161.Sden_3286	4.18e-42	146.0	COG1092@1|root,COG1092@2|Bacteria,1R6GY@1224|Proteobacteria,1RZ4H@1236|Gammaproteobacteria,2QB9C@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_996050_1	1121931.AUHG01000010_gene419	3.74e-18	79.3	COG0824@1|root,COG0824@2|Bacteria,4NS45@976|Bacteroidetes,1I1HB@117743|Flavobacteriia	976|Bacteroidetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
k59_996050_2	411154.GFO_3436	5.44e-76	231.0	COG2105@1|root,COG2105@2|Bacteria,4NQXV@976|Bacteroidetes,1I37H@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1170049_1	1123514.KB905899_gene1789	1.82e-90	278.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,4601P@72273|Thiotrichales	72273|Thiotrichales	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1055853_1	323850.Shew_0348	1.62e-114	346.0	COG0484@1|root,COG0484@2|Bacteria,1MV51@1224|Proteobacteria,1RZ47@1236|Gammaproteobacteria,2Q9EX@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0055114,GO:0070813,GO:0070814,GO:0097159,GO:1901363,GO:1903136	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
k59_1679489_1	1117647.M5M_05225	8.9e-11	62.0	COG0702@1|root,COG0702@2|Bacteria,1NFFF@1224|Proteobacteria	1224|Proteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k59_1679489_2	203122.Sde_3410	3.28e-37	130.0	COG3556@1|root,COG3556@2|Bacteria,1N3XH@1224|Proteobacteria,1T0A8@1236|Gammaproteobacteria,4683E@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
k59_547781_1	1178825.ALIH01000003_gene1997	0.000107	50.4	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1565093_1	572480.Arnit_0597	1.01e-18	78.2	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2YPU9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_1565093_2	572480.Arnit_0596	6.32e-60	190.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,42RN3@68525|delta/epsilon subdivisions,2YPXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	abc transporter atp-binding protein	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_721835_1	572480.Arnit_0474	2.86e-12	65.5	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_721835_2	944547.ABLL_2558	3.8e-112	327.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2YMP6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_378781_1	926562.Oweho_3405	2.44e-100	295.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,1HX59@117743|Flavobacteriia,2PBFJ@246874|Cryomorphaceae	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_324058_1	1168067.JAGP01000001_gene1637	4.09e-106	311.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,460RB@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_774462_1	745718.JADT01000014_gene167	2.16e-75	226.0	2ADU8@1|root,313JX@2|Bacteria,4NQA4@976|Bacteroidetes,1I2S9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_774462_2	1121912.AUHD01000001_gene2327	3.17e-24	100.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1679540_1	1121931.AUHG01000010_gene48	4.76e-45	148.0	2DPDA@1|root,331K9@2|Bacteria,4PCK3@976|Bacteroidetes,1I68R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1342150_1	1123518.ARWI01000001_gene730	3.58e-123	363.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_721886_1	1123518.ARWI01000001_gene1263	1.63e-36	129.0	2E4TM@1|root,32ZMZ@2|Bacteria,1NAT5@1224|Proteobacteria,1SE3M@1236|Gammaproteobacteria,4634R@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1397791_1	402612.FP1262	3.21e-59	198.0	COG0438@1|root,COG0438@2|Bacteria,4NTTB@976|Bacteroidetes,1I9QU@117743|Flavobacteriia,2NX34@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_665774_1	1121887.AUDK01000015_gene893	1.03e-94	303.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2NSFC@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1738641_1	1380600.AUYN01000001_gene2476	1.36e-135	395.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_213777_1	926562.Oweho_1574	3.24e-136	411.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia,2PA9F@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_381521_2	714943.Mucpa_5247	2.38e-32	116.0	COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,1ITXG@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0375 Zn finger protein HypA HybF (possibly regulating hydrogenase expression)	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_381521_3	376686.Fjoh_3906	3.42e-163	464.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1I5EP@117743|Flavobacteriia,2NYDC@237|Flavobacterium	976|Bacteroidetes	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_1567625_1	572480.Arnit_2577	1.24e-201	570.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1285971_1	926562.Oweho_1181	5.06e-56	180.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1I2V8@117743|Flavobacteriia	976|Bacteroidetes	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1116007_1	1380600.AUYN01000001_gene2535	7.54e-190	532.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_155641_1	323850.Shew_3523	3.14e-71	226.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria,2QAPB@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1344773_1	349521.HCH_00401	1.12e-14	73.6	COG0847@1|root,COG0847@2|Bacteria,1N4WX@1224|Proteobacteria,1SC32@1236|Gammaproteobacteria,1XQ3Z@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase III, epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1344773_2	748247.AZKH_1395	7.11e-21	85.9	COG2944@1|root,COG2944@2|Bacteria,1NHAH@1224|Proteobacteria,2VXNT@28216|Betaproteobacteria,2KZEI@206389|Rhodocyclales	206389|Rhodocyclales	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_1738738_1	1237149.C900_03749	2.56e-117	356.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
k59_381596_1	929558.SMGD1_2186	3.87e-89	273.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_606446_1	1380600.AUYN01000001_gene2271	2.54e-165	480.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_101058_1	985255.APHJ01000022_gene3131	2.34e-223	633.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia,2P64A@244698|Gillisia	976|Bacteroidetes	I	B12 binding domain	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_101058_2	1380600.AUYN01000009_gene1833	2.59e-55	180.0	2DPT4@1|root,32UMN@2|Bacteria,4NT6B@976|Bacteroidetes,1I2BM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1397900_1	1121931.AUHG01000011_gene1973	4.18e-57	186.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia	976|Bacteroidetes	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_1397900_2	411154.GFO_2391	3.7e-19	85.9	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Biotin_lipoyl,Na_Ala_symp,SprB
k59_550223_1	929558.SMGD1_1339	3.98e-81	251.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42R7K@68525|delta/epsilon subdivisions,2YP16@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_1397920_1	28258.KP05_06210	1.15e-68	220.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1XIBA@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_1454505_2	90814.KL370892_gene2321	9.87e-71	238.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,462AR@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
k59_1116109_1	1121931.AUHG01000012_gene2843	3.23e-36	126.0	29S8X@1|root,30DDE@2|Bacteria,4NRBB@976|Bacteroidetes,1I28W@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
k59_1116109_2	411154.GFO_1063	5.73e-22	86.7	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1I3YC@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL31 family	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_1286082_1	317025.Tcr_0384	8.3e-82	261.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,45ZVK@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1286082_2	1349785.BAUG01000028_gene1710	8.15e-15	70.9	COG2608@1|root,COG2608@2|Bacteria,4NUWP@976|Bacteroidetes,1I5DZ@117743|Flavobacteriia	976|Bacteroidetes	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
k59_101108_1	675815.VOA_000613	1.04e-23	99.8	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1XV2Z@135623|Vibrionales	135623|Vibrionales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_101108_2	317025.Tcr_1755	5.83e-125	367.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1513498_1	572480.Arnit_0761	8.18e-117	351.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_606493_1	1316936.K678_17061	5.36e-07	52.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2JPNK@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_606493_2	1232410.KI421419_gene2538	1.13e-98	302.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42QMR@68525|delta/epsilon subdivisions,2WJSY@28221|Deltaproteobacteria,43S94@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN-2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_0172	Proton_antipo_M
k59_1116126_1	572480.Arnit_0388	1.92e-67	228.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YMW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,TarH,dCache_2,sCache_2
k59_1567755_1	504487.JCM19302_1219	1.51e-95	292.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_1567755_2	1178825.ALIH01000015_gene1919	1.24e-72	221.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,1I1ZM@117743|Flavobacteriia	976|Bacteroidetes	K	Cold-shock protein	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
k59_1172837_1	1123514.KB905899_gene814	8.09e-48	159.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,460DR@72273|Thiotrichales	72273|Thiotrichales	C	Nitroreductase family	nfnB	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k59_1172837_2	90814.KL370891_gene1209	2.05e-06	47.8	COG4508@1|root,COG4508@2|Bacteria	2|Bacteria	S	dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k59_381672_1	929558.SMGD1_0932	3.07e-102	299.0	2AJZN@1|root,31ANZ@2|Bacteria,1Q5WH@1224|Proteobacteria,42UJ4@68525|delta/epsilon subdivisions,2YPXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1116143_1	388413.ALPR1_08483	3.03e-14	73.9	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_944051_1	1380600.AUYN01000010_gene841	2.11e-87	279.0	COG1196@1|root,COG3064@1|root,COG1196@2|Bacteria,COG3064@2|Bacteria,4NGJZ@976|Bacteroidetes,1HY5X@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	sprD	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF,SPOR
k59_890485_1	1165841.SULAR_03862	9e-114	344.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_606533_1	1178825.ALIH01000006_gene1458	2.1e-162	465.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia	976|Bacteroidetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_381705_1	1172190.M947_07655	2.01e-94	282.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_381720_1	1484460.JSWG01000011_gene1715	2.47e-51	166.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1I1AB@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_1625189_1	1123514.KB905899_gene830	2.76e-135	392.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RSQU@1236|Gammaproteobacteria,463P6@72273|Thiotrichales	72273|Thiotrichales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_890511_1	1123008.KB905693_gene1241	3.79e-07	57.8	COG0702@1|root,COG0702@2|Bacteria,4NEDB@976|Bacteroidetes,2FTXV@200643|Bacteroidia,2304V@171551|Porphyromonadaceae	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_381725_1	411901.BACCAC_00406	1.66e-13	68.9	COG0716@1|root,COG0716@2|Bacteria,4NQ9B@976|Bacteroidetes,2FN7V@200643|Bacteroidia,4APFP@815|Bacteroidaceae	976|Bacteroidetes	C	Low-potential electron donor to a number of redox enzymes	fldA	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_381725_2	1537917.JU82_01555	3.46e-44	145.0	2E67S@1|root,32Q79@2|Bacteria,1N05A@1224|Proteobacteria,42X30@68525|delta/epsilon subdivisions,2YQVD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein NifW	-	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
k59_214016_1	1353276.JADR01000002_gene2125	3.05e-20	85.1	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_214016_2	1178825.ALIH01000009_gene1359	1.32e-57	182.0	2E32X@1|root,32Y35@2|Bacteria,4NUUU@976|Bacteroidetes,1I54Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1075662_3	572480.Arnit_1473	2.4e-23	94.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42RB7@68525|delta/epsilon subdivisions,2YNX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_1471293_1	1165841.SULAR_01963	9.09e-72	226.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2YNY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
k59_1471293_2	326298.Suden_0933	2.43e-11	62.8	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_1132838_1	313595.P700755_002734	2.87e-56	183.0	2DBYI@1|root,2ZBV9@2|Bacteria,4NMM4@976|Bacteroidetes,1I1N0@117743|Flavobacteriia,4C3T4@83612|Psychroflexus	976|Bacteroidetes	S	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1
k59_1245273_1	748247.AZKH_4233	5.8e-118	350.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,2KVEB@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_624562_1	1211112.ALJC01000093_gene1288	3.89e-08	57.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_624562_2	1123518.ARWI01000001_gene2141	0.0	887.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,4609G@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_567869_1	1137281.D778_02762	2.79e-117	343.0	COG1946@1|root,COG1946@2|Bacteria,4NEY8@976|Bacteroidetes,1HZXI@117743|Flavobacteriia	976|Bacteroidetes	I	Thioesterase-like superfamily	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
k59_1358278_1	411154.GFO_1843	9.53e-213	588.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1HXQ7@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1528120_1	1380600.AUYN01000006_gene400	3.79e-34	121.0	2ECCK@1|root,336AW@2|Bacteria,4NW6H@976|Bacteroidetes,1I5HX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1528120_2	1121912.AUHD01000015_gene1132	3.24e-23	98.2	COG0463@1|root,COG0463@2|Bacteria,4PM7X@976|Bacteroidetes,1IJM2@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
k59_795592_1	1123514.KB905901_gene95	3.18e-118	346.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4606H@72273|Thiotrichales	72273|Thiotrichales	P	CBS domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_795592_2	90814.KL370891_gene1708	5.19e-78	235.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,46114@72273|Thiotrichales	72273|Thiotrichales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_795592_3	1123514.KB905901_gene93	8.86e-195	545.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,46094@72273|Thiotrichales	72273|Thiotrichales	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_795592_4	90814.KL370891_gene1710	1.43e-85	265.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,45ZTA@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1021624_1	944547.ABLL_0390	3.29e-25	95.1	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2YQSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k59_1021624_2	572480.Arnit_2815	4.86e-53	182.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_569407_1	1121931.AUHG01000012_gene2713	1.75e-101	297.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia	976|Bacteroidetes	S	Phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_117589_1	90814.KL370891_gene1150	2.58e-99	312.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,4604N@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_117589_2	1123518.ARWI01000001_gene129	8.59e-57	191.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,460AB@72273|Thiotrichales	72273|Thiotrichales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1529523_1	1121931.AUHG01000017_gene1593	1.25e-17	81.6	COG2207@1|root,COG3063@1|root,COG5616@1|root,COG2207@2|Bacteria,COG3063@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_2,TPR_8
k59_1529523_2	1121931.AUHG01000017_gene1592	1.34e-59	192.0	COG0666@1|root,COG0666@2|Bacteria,4NPMU@976|Bacteroidetes,1I020@117743|Flavobacteriia	976|Bacteroidetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
k59_1529523_3	1120951.AUBG01000003_gene2763	5.75e-175	495.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,1I16F@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
k59_1416785_1	323850.Shew_0312	1.43e-129	388.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,2Q911@267890|Shewanellaceae	1236|Gammaproteobacteria	V	SMART AAA ATPase	rtxB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_1077212_1	929558.SMGD1_0651	7.54e-60	202.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2YMKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1077212_2	326298.Suden_1579	2.34e-10	58.5	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2YN9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_908427_1	1120985.AUMI01000011_gene545	4.1e-06	48.5	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	2.7.7.65	ko:K20954,ko:K21088	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_9
k59_908427_2	563040.Saut_1399	2.13e-84	256.0	COG1286@1|root,COG1286@2|Bacteria,1NIBK@1224|Proteobacteria,42U0P@68525|delta/epsilon subdivisions,2YPS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_400243_1	1121931.AUHG01000010_gene326	7.91e-39	139.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1HX67@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
k59_400243_2	411154.GFO_3332	1.87e-176	495.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_1189959_1	317025.Tcr_1715	2.57e-29	117.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,45ZUA@72273|Thiotrichales	72273|Thiotrichales	M	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_1586525_1	926559.JoomaDRAFT_2569	3.82e-114	334.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1HXPA@117743|Flavobacteriia	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1077243_1	1122225.AULQ01000001_gene1660	4e-52	173.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k59_1189971_1	1406840.Q763_09660	3e-139	395.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HZ24@117743|Flavobacteriia,2NT6J@237|Flavobacterium	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1189971_2	1406840.Q763_09665	7.15e-103	300.0	COG0518@1|root,COG0518@2|Bacteria,4NMFC@976|Bacteroidetes,1ID0Q@117743|Flavobacteriia,2NWQD@237|Flavobacterium	976|Bacteroidetes	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k59_287196_1	1137281.D778_02423	8.35e-99	297.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_287196_2	1380600.AUYN01000006_gene284	2.68e-223	620.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_287196_3	1380600.AUYN01000006_gene283	1.64e-265	734.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1HX68@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1643104_1	1123518.ARWI01000001_gene988	1.49e-87	261.0	COG1595@1|root,COG1595@2|Bacteria,1NBAJ@1224|Proteobacteria,1SEK4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_1643104_3	1123518.ARWI01000001_gene990	2.92e-101	303.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,1SC4N@1236|Gammaproteobacteria,462ZF@72273|Thiotrichales	72273|Thiotrichales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
k59_739091_1	926559.JoomaDRAFT_1240	2.66e-210	587.0	COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,4NHNX@976|Bacteroidetes,1I184@117743|Flavobacteriia	976|Bacteroidetes	K	Pfam:DUF955	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
k59_739091_2	926559.JoomaDRAFT_1241	9.47e-46	149.0	COG3549@1|root,COG3549@2|Bacteria,4NWNX@976|Bacteroidetes,1IC1B@117743|Flavobacteriia	976|Bacteroidetes	S	Plasmid maintenance system killer protein	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
k59_964928_1	85643.Tmz1t_2170	1.25e-120	366.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,2KV13@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1246836_1	1137281.D778_00657	5.18e-136	405.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
k59_739092_1	1178825.ALIH01000005_gene196	7.96e-133	382.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1HX11@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
k59_964934_1	572480.Arnit_2515	7.97e-55	176.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
k59_964934_2	1355368.JART01000024_gene1552	4.76e-48	165.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2YN62@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iIT341.HP0957	Glycos_transf_N
k59_1304391_1	236814.IX39_14645	2.57e-41	144.0	COG1045@1|root,COG1045@2|Bacteria,4NJ0X@976|Bacteroidetes,1HZUD@117743|Flavobacteriia,3ZP63@59732|Chryseobacterium	976|Bacteroidetes	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_512692_1	76114.ebA4075	2.31e-74	224.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,2KWGN@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_739130_1	572480.Arnit_2962	1.9e-125	379.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_4764_1	1123518.ARWI01000001_gene2107	5.73e-52	177.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_4764_2	1123518.ARWI01000001_gene2106	2.91e-37	134.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,46283@72273|Thiotrichales	72273|Thiotrichales	P	ABC transporter	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_1586620_1	1121931.AUHG01000010_gene473	1.17e-227	662.0	COG4775@1|root,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,1HX4P@117743|Flavobacteriia	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,ShlB
k59_1586622_1	1123518.ARWI01000001_gene998	3.06e-116	362.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1586624_1	1121931.AUHG01000010_gene308	7.56e-86	258.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,1HYAH@117743|Flavobacteriia	976|Bacteroidetes	S	Creatinine amidohydrolase	crnA	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_1473068_1	1565129.JSFF01000034_gene1486	4.79e-105	315.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,2Q9AK@267890|Shewanellaceae	1236|Gammaproteobacteria	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_739150_1	1380600.AUYN01000007_gene3175	9.22e-169	491.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl endopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_1134371_1	1380600.AUYN01000007_gene3335	2.37e-313	870.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1134371_2	1380600.AUYN01000007_gene3334	8.21e-203	563.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_456989_1	1178825.ALIH01000003_gene2239	5.84e-129	382.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_4791_1	1380600.AUYN01000009_gene1693	5e-144	413.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_4791_2	1137281.D778_00306	2.09e-94	298.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_117768_1	929558.SMGD1_2754	3.33e-56	176.0	2AV85@1|root,31KYU@2|Bacteria,1QITS@1224|Proteobacteria,42SB2@68525|delta/epsilon subdivisions,2YQ0M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117768_2	929558.SMGD1_2755	7.4e-31	112.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2YNVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_1473112_2	326298.Suden_0346	3.45e-29	103.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_1473112_3	1172190.M947_07075	1.3e-16	72.4	COG0690@1|root,COG0690@2|Bacteria,1N8YN@1224|Proteobacteria,42VP0@68525|delta/epsilon subdivisions,2YQ7E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_1304478_2	929558.SMGD1_2388	6.11e-67	206.0	COG4951@1|root,COG4951@2|Bacteria,1PC94@1224|Proteobacteria,42NUB@68525|delta/epsilon subdivisions,2YMWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Domain of unknown function (DUF1882)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1882
k59_457023_1	945713.IALB_0621	7.79e-36	125.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
k59_1699457_1	637905.SVI_2367	1.08e-123	358.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,2Q8XK@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947	ThiG
k59_174569_1	1168067.JAGP01000001_gene123	2.8e-100	311.0	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,460IM@72273|Thiotrichales	72273|Thiotrichales	S	Carboxysome shell peptide mid-region	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
k59_683090_1	391603.FBALC1_09692	1.01e-88	273.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_117782_1	90814.KL370891_gene1078	1.07e-18	83.6	COG3435@1|root,COG3435@2|Bacteria,1RBES@1224|Proteobacteria,1S33X@1236|Gammaproteobacteria,460P2@72273|Thiotrichales	72273|Thiotrichales	Q	Gentisate 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117782_2	1123518.ARWI01000001_gene195	8.03e-228	642.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,46003@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_795825_1	105559.Nwat_2097	4.8e-20	98.6	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales	135613|Chromatiales	M	PFAM AsmA family protein	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k59_343316_1	391587.KAOT1_09576	0.0	961.0	COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia	976|Bacteroidetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
k59_287349_2	760192.Halhy_1024	6.66e-50	171.0	2EF50@1|root,338Y3@2|Bacteria,4NU3V@976|Bacteroidetes,1IU5W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_231076_1	572480.Arnit_2734	2.01e-48	162.0	COG1651@1|root,COG1651@2|Bacteria,1RFRJ@1224|Proteobacteria,42SPD@68525|delta/epsilon subdivisions,2YP88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_231076_2	572480.Arnit_2733	2.37e-53	175.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1246978_1	376686.Fjoh_2198	5.63e-21	90.1	COG0657@1|root,COG0657@2|Bacteria,4NHDX@976|Bacteroidetes,1HXV4@117743|Flavobacteriia,2NTTA@237|Flavobacterium	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
k59_1246978_2	504487.JCM19302_104	6.44e-166	474.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1246978_3	1506583.JQJY01000002_gene1328	9.3e-155	452.0	COG2730@1|root,COG2730@2|Bacteria,4NH83@976|Bacteroidetes,1HYQW@117743|Flavobacteriia,2NV40@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
k59_287351_1	1123518.ARWI01000001_gene763	2.29e-103	305.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,461ZK@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
k59_287351_2	90814.KL370891_gene553	8.7e-51	160.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_287351_3	1121374.KB891576_gene479	9.81e-09	55.5	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_795847_1	563040.Saut_0068	2.65e-26	112.0	COG1352@1|root,COG2201@1|root,COG3290@1|root,COG5000@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3290@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43CSM@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	CheR methyltransferase, SAM binding domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,PAS,PAS_10,PAS_9
k59_1246989_1	411154.GFO_1456	3.51e-219	612.0	COG0642@1|root,COG2205@2|Bacteria,4NG6V@976|Bacteroidetes,1HWTT@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Response_reg
k59_1320861_1	1237149.C900_01718	1.18e-110	332.0	COG1055@1|root,COG1055@2|Bacteria,4NGWD@976|Bacteroidetes,47KPC@768503|Cytophagia	976|Bacteroidetes	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
k59_77868_1	1380600.AUYN01000007_gene3215	1.6e-105	313.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_190729_1	572480.Arnit_2774	1.5e-166	471.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_1201319_1	305700.B447_16884	1.22e-152	438.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,2KV8Q@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_812203_1	1537917.JU82_00175	9.85e-94	284.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_642461_1	991.IW20_02410	2e-110	341.0	COG3866@1|root,COG3866@2|Bacteria,4NHZ1@976|Bacteroidetes,1HZ7I@117743|Flavobacteriia,2NZW9@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
k59_1149101_1	929558.SMGD1_1014	1.29e-62	198.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2YMH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_867832_1	1123400.KB904813_gene3039	6.94e-70	220.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,1S35X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
k59_867832_2	929558.SMGD1_2663	2.16e-70	221.0	COG1705@1|root,COG1705@2|Bacteria,1QA52@1224|Proteobacteria,42ZZX@68525|delta/epsilon subdivisions,2YRWZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
k59_358667_1	1123228.AUIH01000005_gene656	4.26e-73	233.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1XHKR@135619|Oceanospirillales	135619|Oceanospirillales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_1544559_2	929558.SMGD1_1064	5.54e-05	50.1	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2YT3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Thrombospondin type 3 repeat	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
k59_1544559_3	1249480.B649_07375	4.62e-48	167.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_358671_1	1178825.ALIH01000005_gene219	3.72e-180	533.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_923616_1	504487.JCM19302_100	1.32e-157	457.0	COG2730@1|root,COG2730@2|Bacteria,4NH83@976|Bacteroidetes,1HYQW@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
k59_923616_2	362418.IW19_15985	3.16e-73	233.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
k59_585325_1	1349785.BAUG01000012_gene942	6.76e-89	266.0	COG1670@1|root,COG1670@2|Bacteria,4NYNB@976|Bacteroidetes	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_585325_2	509635.N824_13385	4.96e-28	109.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1IRJN@117747|Sphingobacteriia	976|Bacteroidetes	M	synthase	pseI	-	2.5.1.132,2.5.1.56,2.5.1.97	ko:K01654,ko:K15898,ko:K21279	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_1715732_1	1172190.M947_01065	2.35e-72	227.0	29VCT@1|root,30GTA@2|Bacteria,1PZ4I@1224|Proteobacteria,42Q07@68525|delta/epsilon subdivisions,2YNTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1037424_1	945713.IALB_2319	1.33e-38	149.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_1659181_1	748247.AZKH_3623	1.32e-34	134.0	2DBM3@1|root,2Z9WX@2|Bacteria,1R676@1224|Proteobacteria,2VPUB@28216|Betaproteobacteria,2KWS6@206389|Rhodocyclales	206389|Rhodocyclales	S	TIGRFAM PEP-CTERM system associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_358688_1	572480.Arnit_1894	1.46e-87	258.0	COG2185@1|root,COG2185@2|Bacteria,1RB2M@1224|Proteobacteria,42RER@68525|delta/epsilon subdivisions,2YP7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Methylaspartate mutase	mamA	-	5.4.99.1	ko:K01846	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
k59_358688_2	572480.Arnit_1895	5.85e-09	55.8	COG4865@1|root,COG4865@2|Bacteria,1PCBW@1224|Proteobacteria,42PTY@68525|delta/epsilon subdivisions,2YMYF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Methylaspartate mutase	-	-	5.4.99.1	ko:K19268	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_asp_mut_E
k59_867890_1	929558.SMGD1_0357	7.92e-141	421.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_754318_1	90814.KL370891_gene64	7.9e-19	84.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,1T1K8@1236|Gammaproteobacteria,4611F@72273|Thiotrichales	72273|Thiotrichales	I	Thioesterase domain	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_754318_2	1123517.JOMR01000001_gene17	6.14e-38	127.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,4619X@72273|Thiotrichales	72273|Thiotrichales	K	'Cold-shock' DNA-binding domain	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_754318_3	1123518.ARWI01000001_gene1228	5.19e-32	128.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
k59_303442_1	1121931.AUHG01000015_gene1158	1.64e-12	63.5	COG0561@1|root,COG0561@2|Bacteria,4PKY8@976|Bacteroidetes,1I1C5@117743|Flavobacteriia	976|Bacteroidetes	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_416235_1	929558.SMGD1_2297	3.28e-49	162.0	2AIDI@1|root,31TAR@2|Bacteria,1QR0P@1224|Proteobacteria,42TWA@68525|delta/epsilon subdivisions,2YSYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilO
k59_416235_2	1172190.M947_02235	1.43e-22	94.7	2BSDA@1|root,32MF9@2|Bacteria,1Q395@1224|Proteobacteria,42WZ0@68525|delta/epsilon subdivisions,2YQT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_416235_3	929558.SMGD1_2295	4.12e-56	189.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1715782_1	945713.IALB_3064	3.42e-37	127.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	fdx1	-	-	ko:K03522,ko:K05337	-	-	-	-	ko00000,ko04147	-	-	-	Fer4,Fer4_7
k59_1715782_2	1410653.JHVC01000011_gene870	2.8e-13	69.3	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_529044_1	1525715.IX54_06845	3.58e-45	164.0	COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,2U2IV@28211|Alphaproteobacteria,2PWFV@265|Paracoccus	28211|Alphaproteobacteria	P	COG3639 ABC-type phosphate phosphonate transport system permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	-
k59_77985_1	411154.GFO_0400	2.92e-148	427.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_303478_1	929558.SMGD1_2137	2.97e-95	300.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1432244_1	1506583.JQJY01000002_gene1805	6.08e-59	192.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,1I0YN@117743|Flavobacteriia,2NVAI@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
k59_190850_2	1488328.JMCL01000059_gene686	3.31e-85	269.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	bdlA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_9
k59_529070_1	1107311.Q767_03935	2.69e-16	79.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia,2NSX4@237|Flavobacterium	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_529070_2	1178825.ALIH01000005_gene199	1.3e-78	237.0	2B7E4@1|root,320HW@2|Bacteria,4NQP9@976|Bacteroidetes,1I30D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_529070_3	1178825.ALIH01000005_gene198	1.66e-64	203.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia	976|Bacteroidetes	N	gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_1375332_1	1484460.JSWG01000011_gene1713	5.35e-227	646.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
k59_1772449_1	572480.Arnit_1071	9.32e-114	341.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,42NUG@68525|delta/epsilon subdivisions,2YMYA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_1037537_1	945713.IALB_0293	1.12e-57	197.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,HYR,Laminin_G_3,Peptidase_M14
k59_1037547_1	1250232.JQNJ01000001_gene351	1.14e-30	127.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_1201456_1	1237149.C900_01598	1.22e-115	339.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1772486_2	313603.FB2170_01482	3.79e-77	235.0	COG0657@1|root,COG0657@2|Bacteria,4NJ8D@976|Bacteroidetes,1HZX0@117743|Flavobacteriia,2PHAN@252356|Maribacter	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH,Lipase_GDSL_2,Peptidase_S9
k59_247514_1	1484460.JSWG01000012_gene1437	4.68e-94	279.0	COG0580@1|root,COG0580@2|Bacteria,4NFW4@976|Bacteroidetes,1HXX1@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
k59_1375376_1	1353276.JADR01000001_gene93	7.2e-173	492.0	COG4974@1|root,COG4974@2|Bacteria,4NX3Q@976|Bacteroidetes,1HXCN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_78076_1	1121931.AUHG01000010_gene811	2.35e-62	192.0	2CDDY@1|root,32VH2@2|Bacteria,4NT65@976|Bacteroidetes,1I4X4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1092887_2	1484460.JSWG01000012_gene1507	6.13e-27	110.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,1HXDI@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_78086_1	1123514.KB905899_gene992	5.08e-87	266.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,45ZR3@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1375387_1	1120968.AUBX01000017_gene1956	5.84e-45	159.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1375387_2	1120965.AUBV01000005_gene1619	8.56e-38	132.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
k59_1772524_1	1121890.AUDO01000004_gene2211	7.39e-133	380.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1HY7N@117743|Flavobacteriia,2NV1S@237|Flavobacterium	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	pabB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_78097_1	563040.Saut_1945	1.44e-54	194.0	2AK4R@1|root,31AUM@2|Bacteria,1Q66D@1224|Proteobacteria,432H4@68525|delta/epsilon subdivisions,2YSK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF945
k59_812455_1	1380600.AUYN01000001_gene2420	4e-141	411.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_977331_1	563040.Saut_1264	1.6e-133	394.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_1715915_1	1123228.AUIH01000012_gene86	1.37e-83	261.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XHSI@135619|Oceanospirillales	135619|Oceanospirillales	P	Trk system potassium uptake protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_19713_1	76114.ebA5535	6.19e-70	227.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,2KVPJ@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_19713_2	497321.C664_06938	5.31e-45	146.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,2KXAK@206389|Rhodocyclales	206389|Rhodocyclales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
k59_19713_3	497321.C664_06943	2.79e-05	45.8	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KUVY@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1149300_1	929558.SMGD1_1199	9.58e-78	245.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2YMNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1149300_2	929558.SMGD1_1198	0.000483	41.2	COG0597@1|root,COG0597@2|Bacteria,1Q1GU@1224|Proteobacteria,42TMD@68525|delta/epsilon subdivisions,2YPZS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_247569_1	319224.Sputcn32_3667	2.75e-134	384.0	COG4604@1|root,COG4604@2|Bacteria,1QU78@1224|Proteobacteria,1T3Y8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_416395_1	90814.KL370891_gene991	4.2e-117	352.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1432362_1	637905.SVI_0917	1.68e-60	187.0	COG2198@1|root,COG2198@2|Bacteria,1NHRS@1224|Proteobacteria,1SHPH@1236|Gammaproteobacteria,2QBXK@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM Hpt domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_585508_1	945713.IALB_2351	2.45e-60	194.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
k59_585508_2	945713.IALB_2352	2.67e-17	79.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_1149315_1	62928.azo2271	2.47e-124	360.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2W19V@28216|Betaproteobacteria,2KWTS@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_977351_1	929558.SMGD1_0633	3.74e-26	112.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_303636_1	411154.GFO_0148	7.39e-62	199.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HY26@117743|Flavobacteriia	976|Bacteroidetes	M	epimerase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_1715955_1	411154.GFO_3050	1.3e-83	269.0	COG4206@1|root,COG4206@2|Bacteria,4PM93@976|Bacteroidetes,1IJN8@117743|Flavobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1092973_1	1380600.AUYN01000007_gene3161	1.48e-105	311.0	COG0589@1|root,COG0589@2|Bacteria,4NGG8@976|Bacteroidetes,1HYY4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1772621_1	1123234.AUKI01000017_gene2688	1.75e-54	184.0	2BXG3@1|root,2Z82R@2|Bacteria,4NI3Z@976|Bacteroidetes,1I88T@117743|Flavobacteriia	976|Bacteroidetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
k59_1772621_2	1121931.AUHG01000010_gene466	5.51e-87	261.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1HX7K@117743|Flavobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	uxuB_1	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1715975_1	990073.ATHU01000001_gene1794	2.79e-74	226.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,42TEY@68525|delta/epsilon subdivisions,2YPN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrogen fixation protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
k59_1715975_2	1249480.B649_06990	1.08e-34	122.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,42W01@68525|delta/epsilon subdivisions,2YQEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k59_1489884_1	926559.JoomaDRAFT_3185	0.000774	41.2	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_1377080_2	746697.Aeqsu_2118	3.01e-110	323.0	COG0671@1|root,COG0671@2|Bacteria,4NI23@976|Bacteroidetes,1HYR2@117743|Flavobacteriia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_1377080_3	411154.GFO_3455	1.33e-49	161.0	COG0671@1|root,COG0671@2|Bacteria,4NP0U@976|Bacteroidetes,1I0CZ@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_1717465_1	1565129.JSFF01000012_gene569	6.21e-149	434.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,2Q9BY@267890|Shewanellaceae	1236|Gammaproteobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_1491653_1	90814.KL370891_gene378	2.67e-92	275.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,1S75J@1236|Gammaproteobacteria,462RI@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_814371_1	1380600.AUYN01000007_gene3402	1.63e-202	569.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_814371_2	504487.JCM19302_2815	2.66e-120	357.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1150968_1	411154.GFO_3260	1.34e-144	413.0	COG1209@1|root,COG1209@2|Bacteria,4PKUB@976|Bacteroidetes,1IJF6@117743|Flavobacteriia	976|Bacteroidetes	M	COG1209 dTDP-glucose pyrophosphorylase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_1377106_1	1123514.KB905899_gene1959	1.12e-79	243.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales	72273|Thiotrichales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_1377106_2	90814.KL370891_gene90	6.94e-29	103.0	2E5UC@1|root,330IN@2|Bacteria,1NAMZ@1224|Proteobacteria,1SCK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
k59_1377106_3	317025.Tcr_1964	8.38e-110	320.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_374134_1	1123234.AUKI01000017_gene2667	2.03e-41	146.0	COG4225@1|root,COG4225@2|Bacteria,4NIET@976|Bacteroidetes,1I0HZ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861
k59_374134_2	1121931.AUHG01000010_gene457	6.92e-33	125.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,1HZCS@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
k59_1108350_1	746697.Aeqsu_1788	1.47e-158	469.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia	976|Bacteroidetes	CI	phenylacetic acid degradation protein paaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
k59_148482_1	1355374.JARU01000005_gene1838	2.24e-28	112.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2YRDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Putative exonuclease SbcCD, C subunit	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k59_148482_2	102125.Xen7305DRAFT_00009140	2.61e-20	82.8	2EGHB@1|root,33A9F@2|Bacteria	2|Bacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
k59_148482_3	745411.B3C1_18954	3.29e-78	253.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1PF75@1224|Proteobacteria,1RWJG@1236|Gammaproteobacteria,1J7A3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	ATP-dependent endonuclease of the OLD family	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
k59_1447250_2	270374.MELB17_10468	3.12e-73	231.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,1RR46@1236|Gammaproteobacteria,469W6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_488608_1	1001530.BACE01000027_gene526	4.41e-27	107.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S0DD@1236|Gammaproteobacteria,1Y2ZB@135623|Vibrionales	135623|Vibrionales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_599714_1	563040.Saut_0213	4.04e-42	147.0	COG1373@1|root,COG1373@2|Bacteria,1QP8R@1224|Proteobacteria,42SQ9@68525|delta/epsilon subdivisions,2YPG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ATPase (AAA	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
k59_599714_2	563040.Saut_0214	3.9e-18	77.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2YPG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_1447264_1	1293054.HSACCH_00764	3.73e-16	82.8	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_1278511_1	1007096.BAGW01000004_gene1666	1.45e-19	85.9	COG0241@1|root,COG0241@2|Bacteria,1UXGW@1239|Firmicutes,25MSQ@186801|Clostridia,2N8NW@216572|Oscillospiraceae	186801|Clostridia	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
k59_1278511_2	443254.Marpi_1234	5.57e-11	63.5	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	gmhB	-	2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83,5.3.1.28	ko:K00966,ko:K03271,ko:K03273,ko:K15669	ko00051,ko00520,ko00540,ko01100,ko01110,map00051,map00520,map00540,map01100,map01110	M00064,M00114,M00361,M00362	R00885,R05645,R05647,R09768,R09769,R09771,R09772	RC00002,RC00017,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase
k59_769730_2	944547.ABLL_2336	3.42e-78	249.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2YMWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	COG1459 Type II secretory pathway, component PulF	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_769733_1	1172190.M947_04560	5.73e-33	118.0	2AVG9@1|root,31M8F@2|Bacteria,1QJ39@1224|Proteobacteria,42W1H@68525|delta/epsilon subdivisions,2YQB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_769733_2	563040.Saut_0541	2.5e-64	201.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_1337277_1	1288963.ADIS_2283	1.28e-06	50.1	COG2856@1|root,COG2856@2|Bacteria,4NMYC@976|Bacteroidetes	976|Bacteroidetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
k59_991486_1	929558.SMGD1_0903	3.01e-94	296.0	COG1234@1|root,COG2203@1|root,COG3437@1|root,COG1234@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1RGKE@1224|Proteobacteria,42QI9@68525|delta/epsilon subdivisions,2YTB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,PDEase_II
k59_263213_1	504487.JCM19302_2451	2.72e-110	342.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_883405_1	1112217.PPL19_03135	1.49e-06	51.2	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_883405_2	930166.CD58_21170	4.57e-45	157.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Circularly permuted ATP-grasp type 2	IV02_06045	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_1447304_1	504487.JCM19302_1720	6.9e-53	179.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia	976|Bacteroidetes	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_1108415_1	1121935.AQXX01000119_gene4783	2.18e-121	389.0	COG0714@1|root,COG0714@2|Bacteria,1NSN5@1224|Proteobacteria,1RPNN@1236|Gammaproteobacteria,1XNXB@135619|Oceanospirillales	135619|Oceanospirillales	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF3686
k59_991519_1	1123228.AUIH01000022_gene3110	2.76e-55	176.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1XIAU@135619|Oceanospirillales	135619|Oceanospirillales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_263218_1	1380600.AUYN01000006_gene458	1.97e-56	204.0	COG4932@1|root,COG4932@2|Bacteria,4NGMA@976|Bacteroidetes,1IIJH@117743|Flavobacteriia	976|Bacteroidetes	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
k59_263218_2	714943.Mucpa_5261	2.94e-75	247.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,1IUXR@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1390858_1	1197477.IA57_01670	5.84e-33	121.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,1HXQV@117743|Flavobacteriia	976|Bacteroidetes	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_1390858_2	983544.Lacal_1806	2.48e-178	510.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_1390858_3	1347342.BN863_25060	3.78e-70	223.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_543892_1	1123514.KB905902_gene249	6.89e-98	301.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,461XX@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_206301_1	929558.SMGD1_1247	4.13e-91	278.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_599772_1	998674.ATTE01000001_gene3056	7.91e-83	249.0	COG1309@1|root,COG1309@2|Bacteria,1PH2E@1224|Proteobacteria,1RW12@1236|Gammaproteobacteria,46300@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1051745_1	944546.ABED_0820	5.13e-22	98.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,MCPsignal,dCache_1,sCache_2
k59_769779_1	391587.KAOT1_11176	2.82e-105	315.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HWJK@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_769779_2	391587.KAOT1_11181	9.2e-125	365.0	COG3146@1|root,COG3146@2|Bacteria,4NECI@976|Bacteroidetes,1HY9G@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_769779_3	980584.AFPB01000156_gene279	1.79e-117	344.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,1I03U@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k59_1390872_1	886377.Murru_0788	3.95e-40	139.0	COG1595@1|root,COG1595@2|Bacteria,4NMVF@976|Bacteroidetes,1I1G0@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	SatD
k59_431895_1	1121373.KB903626_gene3303	4.4e-81	249.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,47KI4@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_206316_1	572480.Arnit_2474	1.03e-122	369.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1165373_1	563040.Saut_2154	4.17e-40	133.0	2AJEY@1|root,31A0Z@2|Bacteria,1Q4KX@1224|Proteobacteria,4325F@68525|delta/epsilon subdivisions,2YSRD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1165373_2	929558.SMGD1_1236	9.78e-12	65.9	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0D@68525|delta/epsilon subdivisions,2YT4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_828666_1	411154.GFO_1500	9.82e-54	182.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_828666_2	411154.GFO_1499	9.06e-15	73.6	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1HXCP@117743|Flavobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_991555_1	1172190.M947_07115	5.08e-33	127.0	COG1234@1|root,COG2203@1|root,COG3437@1|root,COG1234@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1RGKE@1224|Proteobacteria,42QI9@68525|delta/epsilon subdivisions,2YTB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cAMP phosphodiesterases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,PDEase_II
k59_1447359_1	90814.KL370891_gene1454	4.22e-31	116.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,45ZV3@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
k59_1447359_2	317025.Tcr_1547	3.64e-69	212.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1RMZM@1236|Gammaproteobacteria,460MB@72273|Thiotrichales	72273|Thiotrichales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_1560257_1	572480.Arnit_2391	4.71e-96	291.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,43BTT@68525|delta/epsilon subdivisions,2YTGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1560257_2	1177179.A11A3_13630	5.33e-44	148.0	COG1305@1|root,COG1305@2|Bacteria,1R4TK@1224|Proteobacteria,1RYNT@1236|Gammaproteobacteria,1XJ4C@135619|Oceanospirillales	135619|Oceanospirillales	E	transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_93392_1	398579.Spea_0628	5.3e-62	218.0	COG0642@1|root,COG4251@1|root,COG5000@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_34625_1	929558.SMGD1_1693	3.54e-05	45.1	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_34625_2	929558.SMGD1_1694	7.6e-112	336.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_937954_1	323850.Shew_2516	5.25e-107	323.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,2Q9EN@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM glutamyl-tRNA synthetase class Ic	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
k59_1211592_1	1123518.ARWI01000001_gene1069	4.98e-148	418.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,460YJ@72273|Thiotrichales	72273|Thiotrichales	G	HAD-hyrolase-like	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1211592_2	1123518.ARWI01000001_gene1067	1.84e-60	199.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,460C8@72273|Thiotrichales	72273|Thiotrichales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_206361_2	1123518.ARWI01000001_gene842	6.45e-121	354.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,45ZYH@72273|Thiotrichales	72273|Thiotrichales	NU	twitching motility protein PilT	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1211593_1	326298.Suden_0680	5.4e-112	326.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2YN11@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_769835_1	1123518.ARWI01000001_gene1867	4.58e-213	613.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4624A@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_319263_1	317025.Tcr_1168	9.63e-123	381.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,45ZNT@72273|Thiotrichales	72273|Thiotrichales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_319265_1	1237149.C900_02770	1.93e-74	237.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_263286_1	1401078.HMPREF2140_03315	1.8e-23	99.0	COG1129@1|root,COG1129@2|Bacteria,4PKVD@976|Bacteroidetes,2FM9B@200643|Bacteroidia	976|Bacteroidetes	G	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1621641_2	1123518.ARWI01000001_gene1569	1.27e-75	243.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZS0@72273|Thiotrichales	1236|Gammaproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,dCache_1
k59_37063_2	497321.C664_15963	3.63e-97	284.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2VPZP@28216|Betaproteobacteria,2KW26@206389|Rhodocyclales	206389|Rhodocyclales	P	iron-storage protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_376498_1	1123518.ARWI01000001_gene886	8.37e-135	395.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,460CV@72273|Thiotrichales	72273|Thiotrichales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_376498_2	1123514.KB905899_gene1682	1.78e-55	191.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1SYH1@1236|Gammaproteobacteria,45ZV2@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_265097_1	1484460.JSWG01000004_gene2622	1.4e-126	392.0	COG0697@1|root,COG0697@2|Bacteria,4PKRH@976|Bacteroidetes,1HX4A@117743|Flavobacteriia	976|Bacteroidetes	EG	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_151078_1	1121931.AUHG01000010_gene816	1.61e-21	87.4	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1I2U1@117743|Flavobacteriia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_151078_2	411154.GFO_0157	2.19e-260	716.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k59_1449847_1	317025.Tcr_0038	3.68e-191	536.0	COG1960@1|root,COG1960@2|Bacteria,1NDQ8@1224|Proteobacteria,1S0J8@1236|Gammaproteobacteria,461EM@72273|Thiotrichales	72273|Thiotrichales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_N
k59_993871_1	1250005.PHEL85_2119	3.14e-167	476.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,1HZ6T@117743|Flavobacteriia,3VW8G@52959|Polaribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1,Sugar_tr
k59_1562712_1	326298.Suden_1700	2.77e-53	182.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2YTKV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Bacterial sugar transferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
k59_1339834_1	1137281.D778_01219	1.67e-63	198.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1I17Y@117743|Flavobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1339834_2	1178825.ALIH01000005_gene224	1.66e-124	364.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1HYXA@117743|Flavobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_772155_1	326298.Suden_1437	7.09e-85	262.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42NDE@68525|delta/epsilon subdivisions,2YMNM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase, large subunit	hupL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_491041_3	1122201.AUAZ01000002_gene1084	1.75e-96	316.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CZB,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_1508504_1	945713.IALB_2215	2.9e-13	65.9	COG2001@1|root,COG2001@2|Bacteria	2|Bacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_1508504_2	945713.IALB_2214	1.28e-61	199.0	COG0275@1|root,COG0275@2|Bacteria	2|Bacteria	J	rRNA processing	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_37112_1	1392490.JHZX01000001_gene1302	3.73e-83	258.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1HXSW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_37112_2	45351.EDO27108	2.4e-91	274.0	COG0059@1|root,2QQBF@2759|Eukaryota,38GR1@33154|Opisthokonta,3BZI1@33208|Metazoa	33208|Metazoa	E	Acetohydroxy acid isomeroreductase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	IlvC,IlvN
k59_1053808_1	572480.Arnit_1836	7.69e-88	264.0	COG0368@1|root,COG0368@2|Bacteria,1N4UK@1224|Proteobacteria,42WZT@68525|delta/epsilon subdivisions,2YRS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
k59_1733584_1	1336233.JAEH01000029_gene377	1.34e-306	846.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,2Q8M4@267890|Shewanellaceae	1236|Gammaproteobacteria	T	elongation factor Tu domain 2 protein	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_95935_1	398720.MED217_00595	2.13e-91	286.0	2DBXW@1|root,2ZBRY@2|Bacteria,4NM6W@976|Bacteroidetes,1HYMB@117743|Flavobacteriia,2XJY0@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017
k59_660734_1	944547.ABLL_0732	5.49e-16	76.6	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_660734_2	1122135.KB893146_gene1642	2.27e-06	52.4	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,2VFFK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1449902_1	1178825.ALIH01000001_gene2521	1.76e-124	359.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_1353688_1	90814.KL370891_gene1004	1.6e-138	411.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales	72273|Thiotrichales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_222274_1	944547.ABLL_1941	1.01e-49	169.0	COG0500@1|root,COG2226@2|Bacteria,1NV27@1224|Proteobacteria,42P39@68525|delta/epsilon subdivisions,2YNRW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_1691069_1	1232410.KI421421_gene3588	2.09e-106	321.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1227285_1	1565129.JSFF01000003_gene2124	4.27e-96	285.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,2Q9EE@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM glutamine amidotransferase, class-II	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_674683_1	572480.Arnit_1811	6.56e-72	220.0	COG2897@1|root,COG2897@2|Bacteria,1QVX5@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_674683_2	572480.Arnit_1810	8.35e-23	96.3	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2YMSG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.6,3.1.4.16	ko:K01119,ko:K17224	ko00230,ko00240,ko00920,ko01100,ko01120,map00230,map00240,map00920,map01100,map01120	M00595	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135,R10151	RC00078,RC00296,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_674691_1	929558.SMGD1_2083	3.22e-130	394.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2YR60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1181630_1	1123518.ARWI01000001_gene1058	1.7e-46	160.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	speC	-	4.1.1.17,4.1.1.20	ko:K01581,ko:K01586	ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230	M00016,M00134,M00525,M00526,M00527	R00451,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0864	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1181630_2	1123518.ARWI01000001_gene1059	1.04e-184	515.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,460UY@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1181630_3	1168067.JAGP01000001_gene231	3.45e-107	310.0	COG1586@1|root,COG1586@2|Bacteria,1RH88@1224|Proteobacteria,1S7BA@1236|Gammaproteobacteria,4619B@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
k59_1630367_1	913325.N799_11325	0.000132	43.1	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1X6F1@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1630367_2	1232410.KI421424_gene1584	4.77e-79	253.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria,43U48@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ferrous iron transport protein B C terminus	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_447287_1	641526.ADIWIN_0056	2.88e-18	89.4	COG4886@1|root,COG4932@1|root,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_335623_1	1035193.HMPREF9073_01220	1.21e-10	60.8	COG0028@1|root,COG0028@2|Bacteria,4NH3H@976|Bacteroidetes,1HYIZ@117743|Flavobacteriia,1ERAY@1016|Capnocytophaga	976|Bacteroidetes	EH	Belongs to the TPP enzyme family	poxB	-	1.2.5.1,2.2.1.6	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03145,R04672,R04673,R08648	RC00027,RC00106,RC00860,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_335623_2	1506583.JQJY01000003_gene3216	4.61e-16	75.5	COG2227@1|root,COG2227@2|Bacteria,4NJ5M@976|Bacteroidetes,1I10P@117743|Flavobacteriia,2NUSY@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
k59_733414_1	1123517.JOMR01000001_gene297	3.19e-149	426.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S2WF@1236|Gammaproteobacteria,46277@72273|Thiotrichales	72273|Thiotrichales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k59_1522559_1	1123228.AUIH01000022_gene3126	1.63e-86	278.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIUV@135619|Oceanospirillales	135619|Oceanospirillales	NT	chemotaxis protein	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_222340_1	103690.17131814	7.12e-05	50.4	COG0500@1|root,COG0500@2|Bacteria,1GQ0Q@1117|Cyanobacteria,1HMDW@1161|Nostocales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_335635_1	572480.Arnit_2847	4.2e-100	303.0	COG3400@1|root,COG3400@2|Bacteria,1N5T1@1224|Proteobacteria,42M0B@68525|delta/epsilon subdivisions,2YMCG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain protein	-	-	-	ko:K09944	-	-	-	-	ko00000	-	-	-	TrkA_C
k59_614678_1	867900.Celly_2429	1.83e-75	251.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,1F7X2@104264|Cellulophaga	976|Bacteroidetes	P	TonB dependent receptor	-	GO:0001871,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0004185,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0009987,GO:0010467,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030246,GO:0030247,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044421,GO:0051604,GO:0070008,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:2001070	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1227360_1	1392489.JPOL01000002_gene2689	3.96e-50	169.0	COG4122@1|root,COG4122@2|Bacteria,4NX4T@976|Bacteroidetes,1I5Z6@117743|Flavobacteriia,2XJ7X@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
k59_1294846_1	1380600.AUYN01000009_gene1369	3.14e-73	226.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
k59_1294846_2	1380600.AUYN01000009_gene1370	3.43e-69	218.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1HWR8@117743|Flavobacteriia	976|Bacteroidetes	E	fad dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1522578_1	572480.Arnit_1486	1.64e-85	282.0	COG2304@1|root,COG4254@1|root,COG2304@2|Bacteria,COG4254@2|Bacteria,1QU09@1224|Proteobacteria	1224|Proteobacteria	M	regulator of chromosome condensation, RCC1	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Cadherin,He_PIG,RHS_repeat
k59_614693_1	1121403.AUCV01000005_gene346	2.04e-69	220.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7Z@28221|Deltaproteobacteria,2MPT3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
k59_1227382_1	865937.Gilli_0470	1.52e-31	118.0	29EPR@1|root,3125K@2|Bacteria,4PENA@976|Bacteroidetes,1IF82@117743|Flavobacteriia,2P6ZZ@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1227382_2	1121931.AUHG01000012_gene2634	9.29e-65	204.0	COG0664@1|root,COG0664@2|Bacteria,4NP9Z@976|Bacteroidetes,1I2N5@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_733457_1	1123518.ARWI01000001_gene479	6.15e-85	259.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria,461K5@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
k59_504713_1	1236541.BALL01000006_gene1079	7.21e-25	98.6	COG0454@1|root,COG0454@2|Bacteria,1QUHE@1224|Proteobacteria,1T1Z5@1236|Gammaproteobacteria,2QC9P@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	ysnE	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_504713_2	1002339.HMPREF9373_0149	6.05e-05	45.4	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,3NIUV@468|Moraxellaceae	1236|Gammaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_1691246_2	1123518.ARWI01000001_gene1417	5.46e-37	138.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,46276@72273|Thiotrichales	72273|Thiotrichales	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_674850_1	1121875.KB907547_gene3102	4.4e-79	262.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
k59_1405488_1	62928.azo2887	2.93e-91	290.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,2KVBE@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_559048_1	1121931.AUHG01000010_gene779	2.48e-07	49.3	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
k59_559048_2	411154.GFO_0123	2.91e-51	172.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_1522691_1	1484460.JSWG01000009_gene57	1.74e-108	346.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1522691_2	983544.Lacal_0946	1.72e-146	421.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1575536_1	929558.SMGD1_2752	1.61e-69	214.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2YP0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_1575536_2	929558.SMGD1_2751	5.56e-81	246.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2YM8V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_222478_1	316067.Geob_0438	6.16e-29	109.0	COG0760@1|root,COG0760@2|Bacteria,1QQW0@1224|Proteobacteria,42ZWH@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
k59_1575544_1	1123518.ARWI01000001_gene16	5.95e-170	478.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,45ZX8@72273|Thiotrichales	72273|Thiotrichales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_1353918_2	1296416.JACB01000015_gene4742	1.01e-39	142.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2YJAP@290174|Aquimarina	976|Bacteroidetes	GM	Male sterility protein	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1181809_1	755732.Fluta_2857	5.28e-20	94.7	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,1HXMH@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_674909_1	563040.Saut_0282	1.65e-61	203.0	COG3551@1|root,COG4372@1|root,COG3551@2|Bacteria,COG4372@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_898726_1	1123228.AUIH01000022_gene3080	1.03e-157	447.0	COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,1RZHT@1236|Gammaproteobacteria,1XHVR@135619|Oceanospirillales	135619|Oceanospirillales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
k59_841457_1	388413.ALPR1_09765	1.28e-121	364.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
k59_841457_2	1305737.JAFX01000001_gene2309	5.26e-105	310.0	COG0726@1|root,COG0726@2|Bacteria,4NMJP@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_901251_1	411154.GFO_2873	7.39e-31	110.0	2DP5F@1|root,330KU@2|Bacteria,4NV42@976|Bacteroidetes,1I5KT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_901251_2	411154.GFO_2874	1.34e-130	378.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1HWRB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_278842_1	1565129.JSFF01000039_gene3281	7.39e-162	468.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,2Q92N@267890|Shewanellaceae	1236|Gammaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmF	ccmF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_1750758_1	1123514.KB905902_gene207	7.91e-70	234.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,4625A@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Guanylate_cyc
k59_507255_1	572480.Arnit_2960	7.6e-128	368.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_789325_1	572480.Arnit_0397	5.79e-213	608.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,43BS6@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	nirB	-	1.6.99.3,1.7.1.15	ko:K00362,ko:K03885	ko00190,ko00910,ko01120,map00190,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_52282_1	1367847.JCM7686_1851	2.81e-10	66.2	COG1653@1|root,COG1653@2|Bacteria,1NSTT@1224|Proteobacteria,2UP7C@28211|Alphaproteobacteria,2PZ66@265|Paracoccus	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1
k59_1069841_1	572480.Arnit_0119	1.42e-125	363.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_1184327_1	1123518.ARWI01000001_gene595	3.76e-73	227.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,45ZS6@72273|Thiotrichales	72273|Thiotrichales	D	Belongs to the ParA family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
k59_1184327_2	1123518.ARWI01000001_gene594	4.99e-56	180.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,460EM@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_393243_1	411154.GFO_3535	9.68e-92	294.0	COG1361@1|root,COG1361@2|Bacteria,4PM78@976|Bacteroidetes,1IJZ7@117743|Flavobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
k59_677385_1	1192034.CAP_6332	5.09e-25	107.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
k59_224921_1	1172190.M947_02965	4.04e-71	228.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_224921_2	929558.SMGD1_0728	1.38e-45	152.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_1230055_1	572480.Arnit_0254	5.61e-114	331.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_1069859_1	1121931.AUHG01000010_gene417	2.25e-125	362.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_278873_2	1178825.ALIH01000001_gene2404	5.91e-57	187.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_1127669_1	194439.CT1380	2.36e-06	50.1	2CGDR@1|root,336BW@2|Bacteria,1FFIV@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_617349_2	1380600.AUYN01000009_gene1009	2.42e-124	360.0	COG2267@1|root,COG2267@2|Bacteria,4PKJZ@976|Bacteroidetes,1IJBC@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_112811_1	1172190.M947_00625	1.59e-101	311.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2YN1V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_112811_2	1172190.M947_00620	1.46e-11	63.2	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2YMA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	hydrolase, TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_789389_1	1380600.AUYN01000006_gene490	1.51e-100	300.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HXME@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_1297763_1	1121931.AUHG01000011_gene1846	3.85e-127	365.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_1297763_2	1121931.AUHG01000011_gene1847	9.37e-06	46.6	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1HYHC@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_1465534_1	1123228.AUIH01000041_gene2970	1.15e-83	277.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XJGP@135619|Oceanospirillales	135619|Oceanospirillales	N	Flagellar hook protein flgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_1578272_1	504487.JCM19302_1841	6.4e-113	336.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1693813_1	929558.SMGD1_0540	7.14e-102	309.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YTM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_953681_1	90814.KL370891_gene275	5.5e-89	288.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_844025_1	1408473.JHXO01000004_gene228	1.94e-90	278.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FMB0@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
k59_953686_1	1121912.AUHD01000007_gene525	6.05e-77	239.0	COG2382@1|root,COG2382@2|Bacteria,4PMB2@976|Bacteroidetes,1IJQ3@117743|Flavobacteriia	976|Bacteroidetes	P	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
k59_953686_2	1121912.AUHD01000007_gene526	5.96e-81	263.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31
k59_450090_1	1565129.JSFF01000014_gene395	1.07e-110	325.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,2Q8G6@267890|Shewanellaceae	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
k59_1069958_2	504487.JCM19302_187	5.11e-85	255.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_112895_1	1122225.AULQ01000013_gene138	5.36e-53	172.0	COG4276@1|root,COG4276@2|Bacteria,4NQ3V@976|Bacteroidetes,1I398@117743|Flavobacteriia	976|Bacteroidetes	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_507386_1	1121931.AUHG01000010_gene579	1.38e-28	113.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_677521_1	944547.ABLL_1217	8.67e-117	350.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2YMP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0422	Orn_Arg_deC_N
k59_901457_1	537970.HCAN_1330	2.14e-53	172.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42RMI@68525|delta/epsilon subdivisions,2YT53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k59_901457_2	1396141.BATP01000035_gene4048	5.92e-15	72.8	COG0529@1|root,COG0529@2|Bacteria,46V9Q@74201|Verrucomicrobia,2IU9B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Adenylylsulphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	APS_kinase
k59_798755_2	1121931.AUHG01000011_gene2230	1.32e-121	361.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1HWRV@117743|Flavobacteriia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_798757_1	1175654.A0A0S0N2K6_9CAUD	1.6e-104	331.0	4QBSJ@10239|Viruses,4QXH4@35237|dsDNA viruses  no RNA stage,4QPFJ@28883|Caudovirales,4QKUK@10699|Siphoviridae	10699|Siphoviridae	S	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1589672_2	425104.Ssed_2202	6.07e-28	110.0	2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1TB15@1236|Gammaproteobacteria,2QCDU@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1759032_1	90814.KL370891_gene1591	2.81e-128	383.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,45ZUA@72273|Thiotrichales	72273|Thiotrichales	M	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_798794_1	411154.GFO_2930	1.02e-39	140.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1HYKY@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_798794_2	1121931.AUHG01000011_gene1819	1.34e-72	228.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1702356_1	1121931.AUHG01000011_gene2151	3.66e-82	263.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia	976|Bacteroidetes	EM	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
k59_1191861_1	572480.Arnit_2604	1.13e-121	371.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,42PYN@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124	Transketolase_N
k59_629224_1	62928.azo2209	1.68e-88	266.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1476108_1	1537917.JU82_07115	2.04e-115	357.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions,2YRHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
k59_1532307_1	655815.ZPR_2337	2.02e-110	340.0	COG4399@1|root,COG4399@2|Bacteria,4PM7W@976|Bacteroidetes,1HX9F@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_1024764_1	391603.FBALC1_15577	4.74e-115	357.0	COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,4PKRK@976|Bacteroidetes,1IJDQ@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_798830_1	97139.C824_04525	1.18e-16	82.4	COG4938@1|root,COG4938@2|Bacteria,1V5VH@1239|Firmicutes,24J2U@186801|Clostridia,36NJJ@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
k59_1646063_1	945713.IALB_0475	1.58e-68	214.0	COG0597@1|root,COG0597@2|Bacteria	2|Bacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_403316_1	1121931.AUHG01000010_gene324	2.04e-83	270.0	COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_290247_3	90814.KL370892_gene2324	1.42e-83	248.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,4610B@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k59_290247_4	1123518.ARWI01000001_gene1329	2.32e-78	236.0	COG1416@1|root,COG1416@2|Bacteria,1RKQ1@1224|Proteobacteria,1S6DQ@1236|Gammaproteobacteria,462J1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177633_1	1197477.IA57_05875	2.03e-50	170.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_177633_2	616991.JPOO01000003_gene2159	3.99e-90	271.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1I18P@117743|Flavobacteriia,23H4Q@178469|Arenibacter	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
k59_177633_3	1347342.BN863_33950	3.08e-37	129.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,1I1YE@117743|Flavobacteriia	976|Bacteroidetes	S	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
k59_177649_1	929558.SMGD1_0413	3.25e-39	139.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,42Q1Y@68525|delta/epsilon subdivisions,2YNR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_177649_2	326298.Suden_1688	1.27e-33	125.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42M7C@68525|delta/epsilon subdivisions,2YTS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1589772_2	929558.SMGD1_0795	2.75e-50	161.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2YPYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_1589786_1	1237149.C900_01516	3.73e-87	282.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,47JVJ@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_177669_1	1250278.JQNQ01000001_gene1102	4.08e-70	223.0	COG0438@1|root,COG0438@2|Bacteria,4NJ24@976|Bacteroidetes,1I0P9@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_177669_2	1202532.FF52_07894	1.26e-49	169.0	COG0438@1|root,COG0438@2|Bacteria,4NIXA@976|Bacteroidetes,1HYIA@117743|Flavobacteriia,2NSE0@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_911342_1	1380600.AUYN01000009_gene974	5.3e-104	306.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1HXXM@117743|Flavobacteriia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_1024824_1	1408473.JHXO01000006_gene1166	8.87e-36	126.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,2FMW9@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_1024824_2	1408473.JHXO01000006_gene1165	1.69e-58	186.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,2FN5K@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_1191912_1	929558.SMGD1_1350	1.05e-97	298.0	COG1293@1|root,COG1293@2|Bacteria,1R54S@1224|Proteobacteria,42MYG@68525|delta/epsilon subdivisions,2YT8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k59_1419831_1	641526.ADIWIN_1050	1.87e-92	276.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,1HY5M@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_515823_1	1250278.JQNQ01000001_gene1734	1.55e-49	179.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HYMP@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_234149_1	1121912.AUHD01000006_gene1443	1.88e-218	607.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_234149_2	1223410.KN050846_gene1406	6.98e-121	351.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1HXY6@117743|Flavobacteriia	976|Bacteroidetes	Q	With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_65262_2	1296415.JACC01000023_gene4273	6.65e-27	113.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,2YHNZ@290174|Aquimarina	976|Bacteroidetes	EL	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
k59_1646900_1	425104.Ssed_2300	9.41e-101	303.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,2Q9HA@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390	EPSP_synthase
k59_742612_1	90814.KL370891_gene1471	1.06e-22	96.3	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_742612_2	90814.KL370891_gene1472	1.82e-47	160.0	COG1639@1|root,COG1639@2|Bacteria,1N6RT@1224|Proteobacteria,1SC8B@1236|Gammaproteobacteria,461BN@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1192477_1	1123228.AUIH01000005_gene750	3.14e-16	77.4	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1XH4Y@135619|Oceanospirillales	135619|Oceanospirillales	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
k59_1192477_2	1392838.AWNM01000070_gene1213	8.77e-14	67.0	COG2146@1|root,COG2146@2|Bacteria,1MZBY@1224|Proteobacteria,2VSF0@28216|Betaproteobacteria,3T4UI@506|Alcaligenaceae	28216|Betaproteobacteria	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
k59_1192477_3	391615.ABSJ01000059_gene2154	1.12e-35	135.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1J4KB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Rieske_2
k59_1081010_1	1380600.AUYN01000009_gene1765	2.75e-120	371.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_65301_1	1026882.MAMP_00571	1.8e-63	218.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,1RY4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	outer membrane autotransporter barrel domain	-	-	-	ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Autotransporter,PAP2,PATR,Peptidase_S8
k59_742631_1	411154.GFO_1514	2.25e-08	53.9	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1HWV1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
k59_742631_2	411154.GFO_1513	3.21e-146	422.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	sad	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_686985_1	1123518.ARWI01000001_gene360	8.16e-117	338.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_686985_2	1168067.JAGP01000001_gene881	1.75e-138	392.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,45ZSP@72273|Thiotrichales	72273|Thiotrichales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_686985_3	1123518.ARWI01000001_gene362	1.43e-84	251.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,1S9MI@1236|Gammaproteobacteria,460X6@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
k59_234999_1	1121931.AUHG01000010_gene839	2.23e-50	166.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_742637_2	1178825.ALIH01000004_gene2923	6.65e-15	72.4	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,1I23S@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_346976_1	563040.Saut_2018	9.88e-92	286.0	COG1472@1|root,COG3023@1|root,COG1472@2|Bacteria,COG3023@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2YN15@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Glycosyl hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidase_2,Glyco_hydro_3
k59_178518_1	641526.ADIWIN_0044	4.58e-109	339.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_404197_1	709032.Sulku_0633	7.21e-30	114.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2YMEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_404197_2	709032.Sulku_2320	3.37e-18	80.5	2A14F@1|root,30PAA@2|Bacteria,1Q6CF@1224|Proteobacteria,432V8@68525|delta/epsilon subdivisions,2YSWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_404197_3	1172190.M947_03715	1.16e-10	60.1	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,42NNI@68525|delta/epsilon subdivisions,2YNBH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,Methyltransf_31
k59_1363406_1	1250006.JHZZ01000001_gene571	1.25e-65	214.0	COG2244@1|root,COG2244@2|Bacteria,4NHJV@976|Bacteroidetes,1I0VC@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_8340_1	598659.NAMH_1472	5.42e-23	94.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2YNKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	tigr02757	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_1477043_1	316067.Geob_1799	2.46e-108	318.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
k59_235046_1	411154.GFO_2753	8.16e-74	236.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_235046_2	411154.GFO_2754	8.96e-34	121.0	COG3023@1|root,COG3023@2|Bacteria,4NMIV@976|Bacteroidetes,1HY6G@117743|Flavobacteriia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
k59_404222_1	1168289.AJKI01000022_gene1861	1.97e-52	187.0	COG1203@1|root,COG1203@2|Bacteria	2|Bacteria	L	DNA/RNA hybrid annealing activity	-	-	3.6.4.12	ko:K03657,ko:K07012	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03400	-	-	-	AAA_19,AAA_34,CRISPR_Cse1,DEAD,DUF3991,HD,Helicase_C,Helicase_C_4,ResIII,Toprim_2,UvrD-helicase,UvrD_C_2
k59_178539_1	1123037.AUDE01000011_gene913	8.66e-107	342.0	COG4219@1|root,COG4219@2|Bacteria,4NHAY@976|Bacteroidetes,1HXH6@117743|Flavobacteriia	976|Bacteroidetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
k59_178539_2	1137281.D778_02768	4.57e-73	220.0	COG3682@1|root,COG3682@2|Bacteria,4NP4S@976|Bacteroidetes,1I229@117743|Flavobacteriia	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_855423_4	1203606.HMPREF1526_01838	6.5e-08	64.3	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,36FK8@31979|Clostridiaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1363427_1	563040.Saut_0923	6.54e-97	288.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2YN2X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_1363427_2	929558.SMGD1_2478	3.86e-78	238.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,42KZK@68525|delta/epsilon subdivisions,2YMUM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	dehydrogenase	hdhA	-	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_630167_1	983544.Lacal_2695	8.71e-34	129.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1HYHI@117743|Flavobacteriia	976|Bacteroidetes	J	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_799796_1	666681.M301_1057	2e-53	185.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_516709_2	411154.GFO_2216	1.88e-64	199.0	COG0784@1|root,COG0784@2|Bacteria,4NTMC@976|Bacteroidetes,1I4HG@117743|Flavobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_516711_1	1232410.KI421415_gene2937	1.12e-93	284.0	COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,43DQS@68525|delta/epsilon subdivisions,2X6WA@28221|Deltaproteobacteria,43S6S@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_235089_1	1123037.AUDE01000019_gene3242	1.25e-08	55.8	COG1595@1|root,COG1595@2|Bacteria,4NW2Z@976|Bacteroidetes,1I3EI@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_291164_1	1137281.D778_00359	2e-220	621.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1HXCS@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_687086_1	1380600.AUYN01000009_gene1488	6.17e-130	380.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1HXSE@117743|Flavobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1250907_1	572480.Arnit_2159	8.26e-80	240.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2YNYX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_1250907_2	572480.Arnit_2160	2.52e-19	83.2	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2YMP8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1386	Ribul_P_3_epim
k59_1703326_1	1395571.TMS3_0114870	1.08e-47	166.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_630203_1	317025.Tcr_1101	6.5e-201	576.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,4603V@72273|Thiotrichales	72273|Thiotrichales	C	Isocitrate dehydrogenase NADP-dependent, monomeric type	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_630203_2	317025.Tcr_1108	1.52e-152	442.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1QYKR@1224|Proteobacteria,1T3X5@1236|Gammaproteobacteria,460SR@72273|Thiotrichales	72273|Thiotrichales	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_8424_2	1123367.C666_15405	1.55e-35	127.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,2KWSZ@206389|Rhodocyclales	206389|Rhodocyclales	Q	DSBA Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
k59_1202057_1	563040.Saut_1039	1.5e-22	97.4	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1202057_2	563040.Saut_1040	3.18e-46	152.0	COG0818@1|root,COG0818@2|Bacteria,1Q5TS@1224|Proteobacteria,42SZA@68525|delta/epsilon subdivisions,2YSYV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_1202057_3	563040.Saut_1041	1.42e-13	69.3	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2YM99@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_191783_1	929558.SMGD1_1686	3.67e-181	526.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_586301_1	572480.Arnit_0818	6.58e-116	353.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,43019@68525|delta/epsilon subdivisions,2YRSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_304417_1	1123514.KB905899_gene441	3.9e-99	295.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,1S25V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1093716_1	1463901.JOIY01000017_gene6715	0.000649	45.4	COG0454@1|root,COG0456@2|Bacteria,2IFM6@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_304423_1	1123277.KB893206_gene3275	1.7e-18	92.8	COG0702@1|root,COG0702@2|Bacteria,4NEDB@976|Bacteroidetes,47MB8@768503|Cytophagia	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_643511_1	326298.Suden_0327	1.07e-172	487.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2YM93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_191800_1	317025.Tcr_0774	2.54e-304	838.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZX1@72273|Thiotrichales	72273|Thiotrichales	G	Alpha amylase, catalytic domain	-	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
k59_1322098_1	1123514.KB905899_gene1679	1.02e-92	289.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,45ZQY@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_1322098_2	90813.JQMT01000001_gene461	2.2e-96	293.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,45ZWS@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1716707_1	90814.KL370891_gene1644	7.49e-10	61.2	2AAYF@1|root,310BX@2|Bacteria,1RESE@1224|Proteobacteria,1S5GS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_417270_1	572480.Arnit_0579	1.92e-35	129.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42PDT@68525|delta/epsilon subdivisions,2YN48@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	acid ABC transporter permease	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_417270_2	572480.Arnit_0580	1.9e-91	278.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,42NSB@68525|delta/epsilon subdivisions,2YNCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	acid ABC transporter permease	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_359610_1	1123514.KB905903_gene365	8.17e-118	353.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,1RNZA@1236|Gammaproteobacteria,462PN@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1150135_1	1250278.JQNQ01000001_gene3609	3.86e-54	179.0	COG2130@1|root,COG2130@2|Bacteria,4NGHX@976|Bacteroidetes,1HXE6@117743|Flavobacteriia	976|Bacteroidetes	S	Dehydrogenase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N
k59_977921_1	1123514.KB905900_gene2199	1.87e-101	306.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,460EN@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_643534_1	768671.ThimaDRAFT_3306	2.42e-70	235.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_869010_1	1178825.ALIH01000003_gene1987	5.84e-89	279.0	COG4932@1|root,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_1604513_1	1380600.AUYN01000007_gene3088	1.53e-94	288.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1545779_1	1247963.JPHU01000003_gene1440	2.08e-07	53.9	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg,SBP_bac_3,dCache_1
k59_1545779_2	159087.Daro_3309	1.93e-29	110.0	COG3437@1|root,COG3437@2|Bacteria,1N97G@1224|Proteobacteria,2VW8Q@28216|Betaproteobacteria,2KX9A@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1038540_1	411154.GFO_0020	1.37e-43	152.0	COG2223@1|root,COG2223@2|Bacteria,4PMRK@976|Bacteroidetes,1IJXD@117743|Flavobacteriia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1038540_2	391603.FBALC1_15962	7.19e-38	131.0	2E9NC@1|root,333UV@2|Bacteria,4NVRR@976|Bacteroidetes,1I5P0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1490829_1	745718.JADT01000011_gene738	1.28e-47	160.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1HYZ1@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
k59_21938_1	575788.VS_II1065	8.46e-61	215.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,1T1YN@1236|Gammaproteobacteria,1Y32Z@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg,SBP_bac_3
k59_249838_1	317025.Tcr_1768	7.89e-129	374.0	COG0189@1|root,COG0189@2|Bacteria,1PJQE@1224|Proteobacteria,1RZ2S@1236|Gammaproteobacteria,463PC@72273|Thiotrichales	72273|Thiotrichales	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_305785_1	1121931.AUHG01000016_gene937	4.21e-120	353.0	COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes,1HY2F@117743|Flavobacteriia	976|Bacteroidetes	EGP	Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K03446,ko:K07552	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.2,2.A.1.3	-	-	MFS_1
k59_1434441_1	1121931.AUHG01000012_gene2793	2.57e-86	266.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia	976|Bacteroidetes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_814938_1	1123228.AUIH01000007_gene2603	9.99e-54	189.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XICT@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
k59_1547168_1	563040.Saut_1857	6.2e-127	367.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2YN2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_1661672_1	1380600.AUYN01000001_gene2683	3.51e-69	227.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_1323587_1	1121931.AUHG01000006_gene928	4.44e-25	97.4	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1377669_1	1178825.ALIH01000006_gene1401	6.16e-25	99.8	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_1377669_2	1347342.BN863_12200	3.15e-91	281.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria,4NEAU@976|Bacteroidetes,1HYKC@117743|Flavobacteriia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_644878_1	330214.NIDE3799	2.88e-73	226.0	COG2249@1|root,COG2249@2|Bacteria	2|Bacteria	K	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
k59_475698_1	748247.AZKH_4577	7.01e-71	223.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria,2KVCS@206389|Rhodocyclales	206389|Rhodocyclales	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
k59_814978_1	1123276.KB893279_gene2256	0.000136	52.8	COG0740@1|root,COG0740@2|Bacteria,4NNEB@976|Bacteroidetes	976|Bacteroidetes	OU	Belongs to the peptidase S14 family	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_305851_1	991.IW20_08970	2.9e-119	365.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia,2NSSU@237|Flavobacterium	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1039902_1	929558.SMGD1_2196	3.03e-99	297.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2YMHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_1039902_2	1172190.M947_09745	1.47e-67	210.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,42QQ8@68525|delta/epsilon subdivisions,2YMJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the sigma-70 factor family	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
k59_361034_1	563040.Saut_1136	6.23e-82	254.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_418698_1	1123057.P872_18330	4.77e-10	62.4	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,47KHJ@768503|Cytophagia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_418698_2	1168289.AJKI01000042_gene3726	4.28e-34	130.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,2FSYM@200643|Bacteroidia,3XJRK@558415|Marinilabiliaceae	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_926168_1	1278307.KB907001_gene274	2.83e-45	161.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,2QIZ9@267894|Psychromonadaceae	1236|Gammaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	IV02_00930	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k59_702480_1	983544.Lacal_1700	1.74e-75	244.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_1775066_1	1123514.KB905900_gene2113	3.18e-66	226.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,4602H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1775066_2	317025.Tcr_0008	9.08e-53	186.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,4602H@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
k59_1434541_1	1137281.D778_00233	1.34e-117	352.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia	976|Bacteroidetes	T	gtp-binding protein typa	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_870418_2	1187128.I2GUC6_9CAUD	3.4e-35	132.0	4QBHW@10239|Viruses,4QW8N@35237|dsDNA viruses  no RNA stage,4QTT7@28883|Caudovirales,4QJZQ@10662|Myoviridae	10662|Myoviridae	S	sequence-specific DNA binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_193333_1	563040.Saut_1685	1.5e-128	394.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,43C3Q@68525|delta/epsilon subdivisions,2YTG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_193333_2	563040.Saut_1686	3.63e-74	237.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1265507_1	572480.Arnit_2460	2.59e-78	240.0	COG2214@1|root,COG2214@2|Bacteria,1R4XJ@1224|Proteobacteria	1224|Proteobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_1434564_1	985255.APHJ01000021_gene1559	8.48e-103	313.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1IIH2@117743|Flavobacteriia	976|Bacteroidetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_1095272_1	929558.SMGD1_0617	9.36e-33	120.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2YMW1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_1095272_2	929558.SMGD1_0616	3.7e-125	359.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2YNF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_22076_1	247634.GPB2148_286	1.06e-40	154.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,1RSN5@1236|Gammaproteobacteria,1J91N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1265514_1	1178825.ALIH01000009_gene1320	1.29e-178	504.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1HXT6@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k59_1265514_2	983544.Lacal_1050	4.38e-54	177.0	COG0463@1|root,COG0463@2|Bacteria,4NK1T@976|Bacteroidetes,1HZ1Q@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_531697_1	1123518.ARWI01000001_gene1577	2.69e-100	302.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S66J@1236|Gammaproteobacteria,463BY@72273|Thiotrichales	72273|Thiotrichales	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
k59_926230_1	1144313.PMI10_00672	3.26e-18	80.9	2CIT5@1|root,34742@2|Bacteria,4P5YB@976|Bacteroidetes,1IAGI@117743|Flavobacteriia,2NYKZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_926230_2	1484460.JSWG01000004_gene2538	3.71e-34	122.0	COG3577@1|root,COG3577@2|Bacteria,4NNI0@976|Bacteroidetes,1I1Z6@117743|Flavobacteriia	976|Bacteroidetes	S	protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
k59_644964_1	411154.GFO_2936	2.7e-39	131.0	COG1145@1|root,32SB1@2|Bacteria,4NQ8P@976|Bacteroidetes,1I3IB@117743|Flavobacteriia	976|Bacteroidetes	C	Domain of Unknown Function (DUF326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
k59_644964_2	411154.GFO_2938	4.78e-70	215.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia	976|Bacteroidetes	K	AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1547287_1	1380600.AUYN01000010_gene843	1.29e-93	281.0	COG3064@1|root,COG3064@2|Bacteria,4NESI@976|Bacteroidetes,1HXS4@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_978930_1	326298.Suden_0909	8.53e-156	462.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_587843_1	90814.KL370891_gene284	2.77e-63	199.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,460Y1@72273|Thiotrichales	72273|Thiotrichales	K	L-2,4-diaminobutyric acid acetyltransferase	-	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_475820_1	572480.Arnit_0601	2.04e-114	338.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2YNEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Membrane-bound lytic murein transglycosylase C	mltC	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k59_475820_2	572480.Arnit_0600	2.3e-14	72.4	COG0745@1|root,COG0745@2|Bacteria,1R0ZN@1224|Proteobacteria,43D45@68525|delta/epsilon subdivisions	572480.Arnit_0600|-	KT	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_475823_1	1237149.C900_02879	4.81e-61	191.0	COG1522@1|root,COG1522@2|Bacteria,4NMYA@976|Bacteroidetes,47P8E@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_475823_2	1121373.KB903622_gene2851	1.35e-12	65.1	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,47QMM@768503|Cytophagia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_1151691_1	1121889.AUDM01000004_gene2655	8.74e-25	100.0	2BFVS@1|root,329R5@2|Bacteria,4NSXJ@976|Bacteroidetes,1I43Y@117743|Flavobacteriia,2NXPZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_305963_1	1347342.BN863_17130	1.62e-66	204.0	COG1652@1|root,COG1652@2|Bacteria,4NNRS@976|Bacteroidetes,1I1Y9@117743|Flavobacteriia	976|Bacteroidetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_305963_2	983544.Lacal_2667	1.65e-103	306.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_80389_1	1197477.IA57_01155	8.44e-157	451.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_80389_2	1380600.AUYN01000009_gene1559	2.91e-14	68.2	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,1I2TV@117743|Flavobacteriia	976|Bacteroidetes	P	cytochrome cbb3 oxidase maturation protein CcoH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
k59_418832_1	563040.Saut_1477	1.42e-24	99.8	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2YMHT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	rod shape-determining protein mreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_418832_2	563040.Saut_1476	1.64e-148	427.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2YM9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1151705_1	1123518.ARWI01000001_gene1963	3.09e-92	283.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1QVHK@1224|Proteobacteria,1T2M2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_1323752_1	572480.Arnit_2992	1.22e-164	483.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2YM8Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal,dCache_1
k59_1151723_1	326298.Suden_0135	5.49e-98	305.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2YNJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA binding S1 domain protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1718210_1	323850.Shew_2143	6.45e-25	99.4	COG0635@1|root,COG0635@2|Bacteria,1RETF@1224|Proteobacteria,1S4M5@1236|Gammaproteobacteria,2Q8JA@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1718210_2	318167.Sfri_2316	7.65e-51	169.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,2Q916@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM response regulator receiver	chev-2	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_22172_1	572480.Arnit_1157	1.53e-103	312.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2YN29@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_361198_1	90814.KL370891_gene1837	1.5e-142	412.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,45ZQS@72273|Thiotrichales	72273|Thiotrichales	F	dihydroorotase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_150297_2	1121931.AUHG01000016_gene978	1.64e-17	85.5	COG3209@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,4NK97@976|Bacteroidetes,1HYP5@117743|Flavobacteriia	976|Bacteroidetes	E	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
k59_1621019_1	1380600.AUYN01000009_gene1858	3.38e-132	402.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1449040_1	1202532.FF52_14624	2.14e-135	415.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2NSFC@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_375853_1	317025.Tcr_0007	2e-60	202.0	COG0845@1|root,COG0845@2|Bacteria,1QN99@1224|Proteobacteria,1S0F7@1236|Gammaproteobacteria,4615V@72273|Thiotrichales	72273|Thiotrichales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_659933_1	1237149.C900_01024	3.17e-55	177.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_659933_2	1121904.ARBP01000004_gene922	8.49e-09	55.8	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_1790015_1	1121931.AUHG01000016_gene956	2.11e-109	324.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1676498_1	59919.PMM0276	3.62e-08	61.2	COG0354@1|root,COG0354@2|Bacteria,1GCKN@1117|Cyanobacteria,1MMCP@1212|Prochloraceae	1117|Cyanobacteria	S	Folate-dependent protein for Fe S cluster synthesis repair in oxidative stress	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
k59_1790022_1	1380600.AUYN01000007_gene3249	4.58e-84	279.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1HYCE@117743|Flavobacteriia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_1790022_2	1380600.AUYN01000007_gene3250	2.56e-111	329.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia	976|Bacteroidetes	E	asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
k59_375869_1	1165096.ARWF01000001_gene1517	1.04e-30	111.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,2VW2Y@28216|Betaproteobacteria,2KNY3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_375869_2	317025.Tcr_0629	3.85e-31	112.0	COG2863@1|root,COG2863@2|Bacteria,1NGKI@1224|Proteobacteria,1SGXD@1236|Gammaproteobacteria,462QU@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_718709_1	929558.SMGD1_2130	8.69e-56	183.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2YN42@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_1214920_2	411154.GFO_1481	8.68e-80	260.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_1678910_1	323850.Shew_0238	3.29e-50	168.0	COG3203@1|root,COG3203@2|Bacteria,1R2YH@1224|Proteobacteria,1RYN0@1236|Gammaproteobacteria,2Q8P4@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_1678910_2	225849.swp_2138	5.75e-34	126.0	COG3203@1|root,COG3203@2|Bacteria,1R2YH@1224|Proteobacteria,1RYN0@1236|Gammaproteobacteria,2Q8P4@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_995503_1	425104.Ssed_4374	3.75e-81	243.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,2Q8JW@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Iron-storage protein	ftnA	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008199,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033554,GO:0042221,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0097577,GO:0098771	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k59_1055267_1	563040.Saut_1111	7.53e-12	70.9	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_1055267_2	929558.SMGD1_2648	1.51e-27	108.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2YMKT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_210550_1	1121931.AUHG01000019_gene3004	1.39e-11	62.4	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1112709_1	1349767.GJA_1376	1.28e-40	153.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,47606@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_8,PAS_9,Response_reg
k59_662459_1	1123518.ARWI01000001_gene214	4.94e-212	597.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales	72273|Thiotrichales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1564482_1	1165841.SULAR_08829	1.96e-96	294.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,42NVN@68525|delta/epsilon subdivisions,2YMH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1564482_2	929558.SMGD1_1321	4.52e-12	65.1	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YNF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_38854_1	411154.GFO_3613	5.97e-110	320.0	COG1215@1|root,COG1215@2|Bacteria,4NF6C@976|Bacteroidetes,1HYAR@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_773822_1	693986.MOC_5380	1.21e-14	72.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2UA6G@28211|Alphaproteobacteria,1JW1T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
k59_378166_1	1123037.AUDE01000008_gene746	1.98e-125	369.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_378166_2	1027273.GZ77_01420	3.28e-31	118.0	2DNW1@1|root,32ZFG@2|Bacteria,1NBSM@1224|Proteobacteria,1S8G5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1395182_1	572480.Arnit_0604	4.17e-130	379.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_547249_1	1380600.AUYN01000003_gene25	3.14e-24	98.6	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1HYUA@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_547249_2	391603.FBALC1_12702	1.66e-102	306.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWRZ@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1214978_1	1121931.AUHG01000010_gene239	2.64e-196	547.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_1214978_2	1121931.AUHG01000010_gene240	3.1e-25	97.4	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1564521_1	990073.ATHU01000001_gene1786	1.47e-51	177.0	COG0454@1|root,COG4886@1|root,COG0456@2|Bacteria,COG4886@2|Bacteria,1Q94S@1224|Proteobacteria,42X59@68525|delta/epsilon subdivisions,2YQUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,Pkinase
k59_1623124_1	349124.Hhal_2150	1.34e-41	161.0	COG0517@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG4353@1|root,COG5002@1|root,COG0517@2|Bacteria,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4353@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k59_887716_2	867900.Celly_0198	3.21e-72	223.0	2DM3K@1|root,31JXK@2|Bacteria,4NQKW@976|Bacteroidetes,1I3N0@117743|Flavobacteriia,1FACZ@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_887716_3	1392490.JHZX01000001_gene3110	1.87e-56	181.0	2DRNY@1|root,32URC@2|Bacteria,4NST3@976|Bacteroidetes,1I448@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_887716_4	1178825.ALIH01000005_gene130	1.55e-15	74.7	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_721259_1	1236541.BALL01000034_gene3549	5.41e-40	140.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1RQQK@1236|Gammaproteobacteria,2QA34@267890|Shewanellaceae	1236|Gammaproteobacteria	K	AraC-type transcriptional regulator N-terminus	yqhC	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_152901_1	1121895.Q765_01355	2.67e-05	44.3	2DM4Z@1|root,31R64@2|Bacteria,4NRZQ@976|Bacteroidetes,1I3K5@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
k59_152901_2	1454007.JAUG01000030_gene4423	2e-34	121.0	COG2764@1|root,COG2764@2|Bacteria,4NSNJ@976|Bacteroidetes,1ITJD@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
k59_662559_1	675815.VOA_002765	1.31e-10	64.7	COG0642@1|root,COG0784@1|root,COG4999@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4999@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XV4F@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	barA	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HATPase_c,HisKA,Hpt,Response_reg
k59_323529_2	391587.KAOT1_07838	8.81e-57	182.0	COG0702@1|root,COG0702@2|Bacteria,4NQ3G@976|Bacteroidetes,1I2U6@117743|Flavobacteriia	976|Bacteroidetes	GM	Complex I intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
k59_323529_3	391603.FBALC1_09812	5.29e-09	54.7	2CH3Z@1|root,32RP9@2|Bacteria,4NQUA@976|Bacteroidetes,1I369@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
k59_1679032_1	1172190.M947_06900	3.27e-111	354.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_97753_1	1197477.IA57_05335	9.29e-77	244.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IJAQ@117743|Flavobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_1395248_1	929558.SMGD1_0018	1.04e-125	391.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_1395248_2	326298.Suden_0913	2.52e-50	170.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_378242_1	326298.Suden_0873	2.25e-117	350.0	COG0539@1|root,COG1107@1|root,COG0539@2|Bacteria,COG1107@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2YMBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_1564592_1	1249975.JQLP01000005_gene521	8.96e-236	679.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia,2P6AS@244698|Gillisia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_941509_1	1380600.AUYN01000007_gene3258	6.83e-92	278.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
k59_941509_2	1380600.AUYN01000007_gene3259	1.84e-65	208.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia	976|Bacteroidetes	H	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_995647_1	1280952.HJA_08799	3.25e-21	100.0	COG2273@1|root,COG2273@2|Bacteria,1PG8G@1224|Proteobacteria,2V8W4@28211|Alphaproteobacteria,43XPI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_721334_1	1565129.JSFF01000029_gene3016	2.16e-116	351.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,2Q9JA@267890|Shewanellaceae	1236|Gammaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1215079_1	62928.azo3054	6.97e-87	271.0	COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,2VH7K@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Aldehyde dehydrogenase	boxD	-	1.2.1.77	ko:K15514	ko00362,map00362	-	R09554	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_773968_1	1232410.KI421413_gene879	6.71e-29	121.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42YZM@68525|delta/epsilon subdivisions,2WUH5@28221|Deltaproteobacteria,43TRD@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_266704_1	1123518.ARWI01000001_gene491	8.49e-122	358.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,461NA@72273|Thiotrichales	72273|Thiotrichales	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
k59_266704_2	666681.M301_1425	6.2e-35	125.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,2VUTI@28216|Betaproteobacteria,2KMY9@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1510400_1	929558.SMGD1_1514	1.44e-156	440.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2YMBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome c oxidase, cbb3-type, subunit II	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iIT341.HP0145	FixO
k59_1564663_1	1140.Synpcc7942_0725	8.78e-72	239.0	COG1061@1|root,COG1061@2|Bacteria,1G2HP@1117|Cyanobacteria,1H08U@1129|Synechococcus	1117|Cyanobacteria	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,ResIII
k59_1564676_1	1565129.JSFF01000001_gene1195	6.7e-22	95.1	COG0739@1|root,COG3061@1|root,COG0739@2|Bacteria,COG3061@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,2Q8QT@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M23B	-	-	-	ko:K19304	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	OapA,Peptidase_M23
k59_1564676_2	323850.Shew_1607	1.43e-06	48.1	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S3Z2@1236|Gammaproteobacteria,2Q926@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k59_1215143_1	7159.AAEL015588-PA	2.28e-40	143.0	KOG1199@1|root,KOG1199@2759|Eukaryota,38CCA@33154|Opisthokonta,3BD0V@33208|Metazoa,3CY8V@33213|Bilateria,41TTR@6656|Arthropoda,3SIZ9@50557|Insecta,452SZ@7147|Diptera,45GDF@7148|Nematocera	33208|Metazoa	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.178,1.1.1.35	ko:K08683	ko00280,ko01100,ko01110,ko01130,ko05010,map00280,map01100,map01110,map01130,map05010	-	R04203	RC00525	ko00000,ko00001,ko01000,ko03029,ko04147	-	-	-	adh_short,adh_short_C2
k59_1215143_2	273371.XP_003867034.1	8.28e-15	75.1	COG0183@1|root,KOG1390@2759|Eukaryota,38C4X@33154|Opisthokonta,3NV1W@4751|Fungi,3QPGT@4890|Ascomycota,3RS0R@4891|Saccharomycetes,47ASU@766764|Debaryomycetaceae	4751|Fungi	I	Belongs to the thiolase family	ERG10	GO:0003674,GO:0003824,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006694,GO:0006696,GO:0008150,GO:0008152,GO:0008202,GO:0008204,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016125,GO:0016126,GO:0016128,GO:0016129,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044107,GO:0044108,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0097384,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1395366_1	1178825.ALIH01000018_gene1176	5.81e-165	469.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1HX0Z@117743|Flavobacteriia	976|Bacteroidetes	K	GTP cyclohydrolase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1395366_2	1380600.AUYN01000012_gene2961	1.59e-33	125.0	2CCVV@1|root,2Z7YU@2|Bacteria,4NDUA@976|Bacteroidetes,1HXAA@117743|Flavobacteriia	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_603433_1	1380600.AUYN01000001_gene2269	1.24e-257	734.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_603433_2	1178825.ALIH01000016_gene624	5.05e-69	215.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,1I1ZX@117743|Flavobacteriia	976|Bacteroidetes	M	Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_887890_1	1137281.D778_00137	4.53e-168	478.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
k59_887890_2	1380600.AUYN01000001_gene2305	3.8e-236	663.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1HXCP@117743|Flavobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_1451856_1	929558.SMGD1_1674	7.75e-92	278.0	COG1672@1|root,COG1672@2|Bacteria,1PMVJ@1224|Proteobacteria,42PCP@68525|delta/epsilon subdivisions,2YNZF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Archaea bacterial proteins of	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	DUF234
k59_1564712_1	1565129.JSFF01000027_gene3285	1.18e-83	251.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,2QAN9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_547462_1	709032.Sulku_1289	3.68e-102	309.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2YNN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cofactor biosynthesis protein NifE	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_721448_1	587753.EY04_11600	2.07e-38	143.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,1S2U1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1564723_1	1279009.ADICEAN_02584	7.29e-90	277.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_436365_1	1380600.AUYN01000007_gene3127	6.59e-39	148.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_266791_1	563040.Saut_1340	3.34e-20	85.1	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions,2YPB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Dtw domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DTW
k59_266791_3	563040.Saut_1341	2.41e-24	100.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_1735506_1	1068980.ARVW01000001_gene734	1.46e-14	73.6	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DXA1@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_1735506_2	1123514.KB905901_gene105	5.74e-175	494.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,461VM@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k59_1735506_3	468059.AUHA01000002_gene784	8.68e-81	247.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1IPXK@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k59_1215195_1	985255.APHJ01000039_gene115	7.62e-10	58.9	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia,2P7B0@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1215195_2	985255.APHJ01000039_gene115	3.66e-38	138.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia,2P7B0@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1215195_3	1121931.AUHG01000019_gene3002	6.71e-50	164.0	COG2353@1|root,COG2353@2|Bacteria,4NTB0@976|Bacteroidetes,1I43M@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1112983_1	269798.CHU_1109	3.11e-28	104.0	COG0640@1|root,COG0640@2|Bacteria,4NQCU@976|Bacteroidetes,47QH4@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_1112983_2	1250232.JQNJ01000001_gene3093	2.51e-75	228.0	COG3832@1|root,COG3832@2|Bacteria,4NR9F@976|Bacteroidetes	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_1112983_3	1123276.KB893290_gene5283	8.97e-81	243.0	COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,47P6R@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_1112983_4	143224.JQMD01000002_gene614	1.84e-21	85.9	COG0500@1|root,COG0500@2|Bacteria,4PA7A@976|Bacteroidetes,1I6AG@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173027_1	1123518.ARWI01000001_gene707	6.01e-156	454.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales	72273|Thiotrichales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_624775_1	1137799.GZ78_10170	1.04e-15	80.9	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1XKB8@135619|Oceanospirillales	135619|Oceanospirillales	T	Negative regulator of sigma E activity	mucB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
k59_624775_2	1123228.AUIH01000002_gene1483	5.5e-14	69.3	COG3086@1|root,COG3086@2|Bacteria	2|Bacteria	T	response to oxidative stress	rseC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k59_1697947_1	572477.Alvin_2811	1.86e-99	295.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,1SZ29@1236|Gammaproteobacteria,1X2IZ@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k59_511268_1	1232410.KI421413_gene866	6.02e-119	364.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43SDH@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PEP-utilising enzyme, N-terminal	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_1020299_1	1123514.KB905899_gene1785	7e-114	333.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,460XV@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_229483_1	572480.Arnit_2234	2.84e-29	105.0	COG2841@1|root,COG2841@2|Bacteria,1PJVM@1224|Proteobacteria,42X87@68525|delta/epsilon subdivisions,2YQQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
k59_229483_2	572480.Arnit_2235	3.02e-33	124.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1245477_1	1293054.HSACCH_02443	1.91e-11	63.5	COG0438@1|root,COG0438@2|Bacteria,1UYM0@1239|Firmicutes,24Q93@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_1245477_2	504487.JCM19302_987	1.41e-13	73.9	COG1143@1|root,COG1143@2|Bacteria,4PMG7@976|Bacteroidetes	976|Bacteroidetes	C	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
k59_341789_1	326298.Suden_1549	1.86e-94	295.0	COG1629@1|root,COG4771@2|Bacteria,1MXY7@1224|Proteobacteria,42MSN@68525|delta/epsilon subdivisions,2YN7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_116326_1	323850.Shew_3478	4.31e-115	341.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,2Q8XS@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2830,iLF82_1304.LF82_0116,iNRG857_1313.NRG857_13920,iYL1228.KPN_03226	AA_kinase,Acetyltransf_1
k59_511285_1	1237149.C900_00727	2.7e-08	54.3	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_511285_2	1197477.IA57_11200	1.58e-30	114.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_794294_1	572480.Arnit_0123	7.88e-25	97.4	COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,43B1K@68525|delta/epsilon subdivisions,2YT55@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COGs COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_794294_2	572480.Arnit_0124	1.78e-56	185.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1245491_1	1336803.PHEL49_1543	3.84e-154	454.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia,3VX39@52959|Polaribacter	976|Bacteroidetes	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
k59_285868_1	1121931.AUHG01000011_gene2309	2.82e-36	128.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
k59_737763_1	765914.ThisiDRAFT_1401	1.01e-93	285.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_229510_1	1336233.JAEH01000014_gene3496	5.28e-102	298.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,2QAEM@267890|Shewanellaceae	1236|Gammaproteobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1302889_1	572480.Arnit_2974	7.38e-79	242.0	COG1034@1|root,COG1034@2|Bacteria,1Q52A@1224|Proteobacteria,42SHE@68525|delta/epsilon subdivisions,2YN68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ATP synthesis coupled electron transport	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	-
k59_1302889_2	572480.Arnit_2975	1.72e-50	161.0	2AITQ@1|root,319AS@2|Bacteria,1Q26T@1224|Proteobacteria,42V2V@68525|delta/epsilon subdivisions,2YQFN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	putative NADH-ubiquinone oxidoreductase chain E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH-UOR_E
k59_1302889_3	572480.Arnit_2976	6.11e-36	131.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_907218_1	563040.Saut_0307	3.57e-38	130.0	COG0526@1|root,COG0526@2|Bacteria,1QZ1W@1224|Proteobacteria,43CE3@68525|delta/epsilon subdivisions,2YTBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
k59_907218_2	326298.Suden_0341	3.91e-57	186.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1471606_1	929558.SMGD1_0627	3.52e-97	303.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2YNE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k59_341821_1	929558.SMGD1_0741	2.53e-86	262.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2YPMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_341821_2	1172190.M947_02885	7.87e-122	365.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2YM7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0354	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_1075935_1	865937.Gilli_0204	3.82e-123	355.0	COG0500@1|root,COG2226@2|Bacteria,4NFXT@976|Bacteroidetes,1I145@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase type 11	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_1641806_1	90814.KL370892_gene2252	7.66e-119	355.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_116377_1	944547.ABLL_0877	2.2e-17	81.3	COG0745@1|root,COG0745@2|Bacteria,1PFGE@1224|Proteobacteria,42U08@68525|delta/epsilon subdivisions,2YPVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_116377_2	1122197.ATWI01000015_gene815	4.2e-10	67.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,464KE@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_455548_1	1123228.AUIH01000001_gene1181	8.07e-58	200.0	COG0210@1|root,COG0210@2|Bacteria,1MXWE@1224|Proteobacteria,1RP5D@1236|Gammaproteobacteria,1XIJR@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1075947_1	411154.GFO_3050	1.93e-138	413.0	COG4206@1|root,COG4206@2|Bacteria,4PM93@976|Bacteroidetes,1IJN8@117743|Flavobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_624855_1	1123228.AUIH01000014_gene300	1.48e-97	297.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1XHGX@135619|Oceanospirillales	135619|Oceanospirillales	V	protein conserved in bacteria	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_341849_1	317025.Tcr_1020	5.96e-76	238.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,1RMG8@1236|Gammaproteobacteria,463G5@72273|Thiotrichales	72273|Thiotrichales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2
k59_1245546_1	1249480.B649_00565	4.88e-24	99.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_1415575_1	411154.GFO_2539	2.04e-125	372.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia	976|Bacteroidetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_341860_1	319224.Sputcn32_2895	4.2e-140	405.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,1RYD6@1236|Gammaproteobacteria,2QB5G@267890|Shewanellaceae	1236|Gammaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
k59_1528420_1	411154.GFO_1883	1.5e-91	285.0	COG1345@1|root,COG1345@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia	976|Bacteroidetes	N	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_341878_1	1168067.JAGP01000001_gene35	1.14e-78	257.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,4609C@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k59_794389_1	1121875.KB907549_gene1926	1.52e-50	168.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia	976|Bacteroidetes	O	molecular chaperone	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_794389_2	1250005.PHEL85_2282	8.31e-33	116.0	2E3D8@1|root,32YCF@2|Bacteria,4NUPM@976|Bacteroidetes,1I544@117743|Flavobacteriia,3VXBF@52959|Polaribacter	976|Bacteroidetes	S	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_2
k59_794389_3	886377.Murru_0440	2.26e-28	108.0	2CMQC@1|root,32SFB@2|Bacteria,4NU5B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1585253_1	523791.Kkor_2388	1.18e-49	167.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria,1XKCU@135619|Oceanospirillales	135619|Oceanospirillales	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_1585253_2	1123518.ARWI01000001_gene398	3.02e-49	175.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S1QJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_963618_1	504487.JCM19302_315	1.15e-88	277.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_455599_1	425104.Ssed_0591	1.44e-08	53.9	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,1S6MA@1236|Gammaproteobacteria,2QBXW@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_455599_2	425104.Ssed_0592	4.39e-35	132.0	COG0840@1|root,COG0840@2|Bacteria,1RIXH@1224|Proteobacteria,1S7AG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_794393_1	1380600.AUYN01000006_gene607	3.92e-168	471.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_794393_2	1380600.AUYN01000006_gene606	1e-140	407.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia	976|Bacteroidetes	N	Cell envelope biogenesis protein OmpA	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_794393_3	1122225.AULQ01000002_gene493	6.16e-66	210.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1HY7T@117743|Flavobacteriia	976|Bacteroidetes	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_341895_1	938709.AUSH02000017_gene979	8.75e-46	169.0	COG2373@1|root,COG2911@1|root,COG3291@1|root,COG4935@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	psrP1	-	-	ko:K12548,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,CHU_C,DUF11,SWM_repeat,SdrD_B,SprB,fn3
k59_907304_1	1408473.JHXO01000006_gene1132	4.01e-17	84.7	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k59_907304_2	483216.BACEGG_01594	5.85e-15	72.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,2FP0R@200643|Bacteroidia,4AP00@815|Bacteroidaceae	976|Bacteroidetes	FJ	Cytidine and deoxycytidylate deaminase zinc-binding region	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
k59_341899_1	1123228.AUIH01000007_gene2605	2.56e-82	252.0	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RYBE@1236|Gammaproteobacteria,1XR82@135619|Oceanospirillales	135619|Oceanospirillales	L	COG3568 Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1641875_1	1123228.AUIH01000012_gene90	5.4e-65	207.0	COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,1RS9Y@1236|Gammaproteobacteria,1XQYW@135619|Oceanospirillales	135619|Oceanospirillales	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1415627_1	1121931.AUHG01000016_gene1046	1.18e-73	237.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
k59_794416_2	572480.Arnit_2485	8.52e-23	95.5	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_341909_1	1123518.ARWI01000001_gene463	1.39e-07	51.6	COG3195@1|root,COG3195@2|Bacteria,1RH9S@1224|Proteobacteria,1S25P@1236|Gammaproteobacteria,463GU@72273|Thiotrichales	72273|Thiotrichales	S	OHCU decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox
k59_341909_2	1123518.ARWI01000001_gene462	3.65e-107	309.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,1RQ4C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	GO:0000310,GO:0003674,GO:0003824,GO:0004422,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0032265,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iSbBS512_1146.SbBS512_E0235	Pribosyltran
k59_341909_3	1168067.JAGP01000001_gene457	2.31e-38	129.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,4639A@72273|Thiotrichales	72273|Thiotrichales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_455623_1	273121.WS0850	3.13e-44	174.0	COG0642@1|root,COG0715@1|root,COG0784@1|root,COG0834@1|root,COG2198@1|root,COG0715@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_399059_1	225937.HP15_2086	2.81e-19	87.8	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,464B7@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_399059_2	1168067.JAGP01000001_gene953	4.49e-104	306.0	COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,460TW@72273|Thiotrichales	72273|Thiotrichales	S	High frequency lysogenization protein hflD homolog	hflD	-	-	ko:K07153	-	-	-	-	ko00000	-	-	-	DUF489
k59_399059_3	1313304.CALK_0298	1.82e-33	117.0	COG3450@1|root,COG3450@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
k59_399059_4	1123518.ARWI01000001_gene340	4.77e-81	261.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_1076034_1	992406.RIA_2139	9.75e-10	60.1	COG2602@1|root,COG2602@2|Bacteria,4NH11@976|Bacteroidetes,1HYKK@117743|Flavobacteriia	976|Bacteroidetes	V	Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838,ko:K22351	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000,ko01504	-	-	-	Transpeptidase
k59_1076034_2	394.NGR_c00950	4.36e-33	118.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2U9EH@28211|Alphaproteobacteria,4BEBP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
k59_907324_1	696281.Desru_0237	4.5e-20	92.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,261DG@186807|Peptococcaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
k59_907324_2	62928.azo3488	1.13e-20	88.6	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,2KV23@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k59_286012_1	1348583.ATLH01000015_gene305	3.83e-209	608.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia,1F9XT@104264|Cellulophaga	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1358625_2	1172190.M947_02710	1.02e-54	186.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1415654_1	706587.Desti_2499	5.37e-15	73.9	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2WQA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM multiple antibiotic resistance (MarC)-related protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_455639_1	1123517.JOMR01000001_gene747	5.79e-32	118.0	2DVWM@1|root,33XH4@2|Bacteria,1NVNQ@1224|Proteobacteria,1SP70@1236|Gammaproteobacteria,462EE@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_455639_2	90814.KL370891_gene1364	1.92e-58	185.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,4609I@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_286014_1	1178825.ALIH01000001_gene2318	2e-212	621.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_963683_1	504487.JCM19302_3220	2.12e-202	567.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_850188_1	1442598.JABW01000012_gene394	6.01e-162	468.0	COG0348@1|root,COG0348@2|Bacteria,1PYJZ@1224|Proteobacteria,43ABT@68525|delta/epsilon subdivisions,2YRDV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_624987_1	326298.Suden_1993	3.29e-39	142.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2YN30@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_624987_2	929558.SMGD1_2746	2.43e-23	97.1	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1020509_1	313606.M23134_06636	3.3e-13	63.9	COG1942@1|root,COG1942@2|Bacteria,4NV4Q@976|Bacteroidetes,47SGK@768503|Cytophagia	976|Bacteroidetes	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_1020509_2	1125863.JAFN01000001_gene1338	1.29e-22	92.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	yvoD	-	-	-	-	-	-	-	-	-	-	-	Gate
k59_1415682_1	867902.Ornrh_0974	9.35e-39	144.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_1585337_1	326298.Suden_0661	7.59e-23	96.3	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1585337_2	326298.Suden_0662	2.67e-52	164.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2YPVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Ferredoxin	fdxB	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4
k59_1585337_3	563040.Saut_0689	4.6e-20	88.2	COG0642@1|root,COG2205@2|Bacteria,1QUJ5@1224|Proteobacteria,42NJC@68525|delta/epsilon subdivisions,2YMGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cosS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_288480_2	945713.IALB_0960	1.76e-12	67.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_1474310_2	90814.KL370892_gene2336	1.36e-72	248.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_684271_1	522772.Dacet_1734	1.17e-15	78.6	COG2200@1|root,COG2200@2|Bacteria,2GGAV@200930|Deferribacteres	200930|Deferribacteres	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_184909_1	985255.APHJ01000028_gene948	1.07e-112	329.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,1HYJI@117743|Flavobacteriia,2P5GN@244698|Gillisia	976|Bacteroidetes	GM	COGs COG1682 ABC-type polysaccharide polyol phosphate export systems permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
k59_184909_2	411154.GFO_0541	0.00017	42.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1I4FI@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_1257050_1	992406.RIA_0694	1.29e-24	100.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1HWMU@117743|Flavobacteriia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_1257050_2	745718.JADT01000004_gene1258	3.71e-33	115.0	COG0690@1|root,COG0690@2|Bacteria,4NV63@976|Bacteroidetes,1I536@117743|Flavobacteriia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_1257050_3	1137281.D778_00186	6.49e-09	54.7	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1HWPB@117743|Flavobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_523027_1	1172190.M947_03945	5.06e-18	83.2	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2YNIG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
k59_523027_2	563040.Saut_1582	8.52e-115	334.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2YMI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_71804_1	743722.Sph21_3387	1.3e-31	121.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,1INP4@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
k59_71804_2	1237149.C900_05680	9.51e-42	148.0	COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,47NP1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k59_241332_1	283699.D172_3464	1.85e-36	140.0	COG1835@1|root,COG1835@2|Bacteria,1RHQR@1224|Proteobacteria,1SA9E@1236|Gammaproteobacteria,2Q13D@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1597143_1	1123518.ARWI01000001_gene484	2.89e-81	252.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,461TK@72273|Thiotrichales	72273|Thiotrichales	E	Peptidase family M28	-	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_1143690_1	1565129.JSFF01000005_gene2357	5.99e-102	310.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,2Q8YP@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_2885	ATP-grasp_3,Glu_cys_ligase
k59_241338_1	323850.Shew_2421	1.42e-111	355.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QA47@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
k59_1483677_1	458817.Shal_2867	9.96e-36	139.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,2Q9QV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035434,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060003,GO:0061687,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071292,GO:0071944,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:1902601,GO:1990169	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	iEC55989_1330.EC55989_0497,iECIAI1_1343.ECIAI1_0487,iECO103_1326.ECO103_0460,iECSE_1348.ECSE_0509,iECW_1372.ECW_m0557,iEKO11_1354.EKO11_3363,iWFL_1372.ECW_m0557	E1-E2_ATPase,HMA,Hydrolase
k59_1143698_1	1380600.AUYN01000010_gene866	4.41e-126	383.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1766450_1	1123514.KB905899_gene1003	1.06e-30	119.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,461GB@72273|Thiotrichales	72273|Thiotrichales	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_71833_1	929558.SMGD1_0379	5.9e-08	51.2	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_71833_2	929558.SMGD1_0378	6.97e-66	225.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1483710_1	929558.SMGD1_1281	9.05e-110	331.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_467279_1	929558.SMGD1_2814	1.49e-41	149.0	COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
k59_467279_2	563040.Saut_1276	9.28e-24	99.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2YMK9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k59_1143718_1	326298.Suden_0909	4.67e-111	344.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_636651_1	1336803.PHEL49_0720	1.93e-80	269.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_353153_1	504487.JCM19302_3245	4.8e-145	416.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_580011_1	944547.ABLL_0128	2.17e-115	341.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_412322_1	1250278.JQNQ01000001_gene1668	2.21e-84	259.0	COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,1HZX4@117743|Flavobacteriia	976|Bacteroidetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_1541082_1	326298.Suden_1644	5.43e-73	237.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2YMRM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_695687_1	411154.GFO_0066	3.41e-13	66.6	28JKT@1|root,2Z9DG@2|Bacteria,4NJJK@976|Bacteroidetes,1HYPI@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
k59_695687_2	411154.GFO_0067	9.87e-70	211.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
k59_695687_3	411154.GFO_0068	2.51e-91	272.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_299419_1	572480.Arnit_0390	1.1e-62	203.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	glnL	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,TPR_16,TPR_19,TPR_8,YcbB
k59_299419_2	572480.Arnit_0389	1.55e-09	55.5	COG2138@1|root,COG2138@2|Bacteria,1PRX7@1224|Proteobacteria,42VX1@68525|delta/epsilon subdivisions,2YSGT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cobalt chelatase (CbiK)	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
k59_1371495_1	242619.PG_1056	2.29e-08	53.1	COG0720@1|root,COG0720@2|Bacteria,4PIUG@976|Bacteroidetes,2FSF1@200643|Bacteroidia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_1371495_2	1175654.A0A0S0N787_9CAUD	9.8e-92	274.0	4QH75@10239|Viruses,4QWW9@35237|dsDNA viruses  no RNA stage,4QQZ4@28883|Caudovirales,4QKSF@10699|Siphoviridae	10699|Siphoviridae	S	GTP cyclohydrolase I activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1371495_3	1175654.A0A0S0MVN0_9CAUD	8.24e-177	498.0	4QFED@10239|Viruses,4R072@35237|dsDNA viruses  no RNA stage,4QPEH@28883|Caudovirales,4QN2V@10699|Siphoviridae	10699|Siphoviridae	S	tRNA modification	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1371495_4	1538804.A0A088FAQ9_9CAUD	3.3e-98	298.0	4QFYS@10239|Viruses,4QUD0@28883|Caudovirales,4QMR9@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_469296_1	991.IW20_03685	3.53e-48	165.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1I5EP@117743|Flavobacteriia,2NYDC@237|Flavobacterium	976|Bacteroidetes	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_469296_2	376686.Fjoh_3907	1.48e-127	379.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1I3BR@117743|Flavobacteriia,2NYJF@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1316978_2	504487.JCM19302_2156	1.79e-31	112.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia	976|Bacteroidetes	S	related to 2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_355075_1	929703.KE386491_gene1764	8.99e-113	358.0	COG4206@1|root,COG4206@2|Bacteria,4PNAG@976|Bacteroidetes,47YAC@768503|Cytophagia	976|Bacteroidetes	H	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_73877_1	857087.Metme_2941	1.67e-66	227.0	COG2199@1|root,COG2203@1|root,COG2703@1|root,COG4191@1|root,COG4936@1|root,COG2203@2|Bacteria,COG2703@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_525083_1	1237149.C900_03098	4.14e-79	251.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,47NRA@768503|Cytophagia	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_864012_1	90814.KL370891_gene1473	9.52e-30	118.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T239@1236|Gammaproteobacteria,4625C@72273|Thiotrichales	72273|Thiotrichales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_864012_2	90813.JQMT01000001_gene75	1.16e-33	118.0	COG0011@1|root,COG0011@2|Bacteria,1N8R0@1224|Proteobacteria,1SCF3@1236|Gammaproteobacteria,46157@72273|Thiotrichales	72273|Thiotrichales	S	YKOF-related Family	-	-	-	-	-	-	-	-	-	-	-	-	Ykof
k59_864012_3	90814.KL370891_gene1477	3.69e-46	154.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,462BG@72273|Thiotrichales	72273|Thiotrichales	H	Nicotinamide mononucleotide transporter	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
k59_16005_1	1565129.JSFF01000004_gene3163	7.01e-118	353.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,2QATG@267890|Shewanellaceae	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_355101_1	1449049.JONW01000006_gene2978	4e-36	131.0	COG2203@1|root,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
k59_581867_1	879212.DespoDRAFT_02931	2.22e-117	346.0	28J8Y@1|root,2Z943@2|Bacteria,1REXC@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k59_1371532_1	504487.JCM19302_2312	1.74e-108	323.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1HY15@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
k59_1371535_1	1168067.JAGP01000001_gene586	7.92e-76	246.0	COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,4607W@72273|Thiotrichales	72273|Thiotrichales	M	sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
k59_1089050_1	1121912.AUHD01000020_gene3405	3.21e-40	144.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1HY1N@117743|Flavobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
k59_1089050_2	1353276.JADR01000001_gene311	4.64e-29	109.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1HZGZ@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_974298_1	563040.Saut_0862	2.15e-142	415.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K02653,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_974298_2	1172190.M947_02260	7.11e-29	114.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_864034_1	563040.Saut_1448	7.38e-93	282.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42M54@68525|delta/epsilon subdivisions,2YNPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_1428587_1	1168067.JAGP01000001_gene2011	3e-126	395.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,MCPsignal,PAS_3,PAS_8,PAS_9
k59_1089058_1	1123514.KB905902_gene245	1.9e-158	466.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,45ZQH@72273|Thiotrichales	72273|Thiotrichales	E	peptidase	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1711835_1	1137281.D778_02759	3.09e-37	131.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I28Y@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
k59_1711835_2	1137281.D778_02760	7.73e-119	350.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia	976|Bacteroidetes	S	Flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_525134_1	1121931.AUHG01000011_gene2029	1.59e-110	322.0	COG0526@1|root,COG0526@2|Bacteria,4NMNR@976|Bacteroidetes,1IJ9P@117743|Flavobacteriia	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
k59_1485812_1	572480.Arnit_0891	2.16e-63	196.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_1485812_2	572480.Arnit_0890	2.08e-147	416.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2YNF2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 1	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_1145642_1	62928.azo0678	7.05e-05	43.9	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2VJUP@28216|Betaproteobacteria,2KV7I@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter, ATP-binding protein	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
k59_1145642_2	62928.azo0679	7.08e-104	307.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2VJ6D@28216|Betaproteobacteria,2KW23@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_638656_1	929558.SMGD1_1444	2.82e-119	353.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2YMU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_638656_2	929558.SMGD1_1443	9.76e-56	196.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2YMM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k59_1033646_1	1123514.KB905899_gene532	7.49e-105	314.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,45ZNF@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k59_73970_1	1232683.ADIMK_2022	4.19e-13	70.1	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
k59_1428637_1	1172190.M947_04380	1.04e-128	373.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2YMMA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iIT341.HP0202	ACP_syn_III,ACP_syn_III_C
k59_808202_1	929558.SMGD1_2291	1.36e-103	316.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_1259243_1	1120951.AUBG01000006_gene520	7.2e-74	234.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_1145691_1	944546.ABED_2019	1.46e-18	87.0	2FGCU@1|root,34890@2|Bacteria,1P1W4@1224|Proteobacteria,42VMW@68525|delta/epsilon subdivisions,2YSCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1145691_2	521096.Tpau_1589	8.19e-15	74.3	COG0323@1|root,COG0323@2|Bacteria,2IATP@201174|Actinobacteria	201174|Actinobacteria	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k59_1428651_1	748247.AZKH_0641	3.98e-81	252.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,2KVSV@206389|Rhodocyclales	206389|Rhodocyclales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1655440_1	1123518.ARWI01000001_gene542	1.93e-71	222.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,46036@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_1541221_1	323850.Shew_2211	2.74e-110	325.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,2QA59@267890|Shewanellaceae	1236|Gammaproteobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735	SAICAR_synt
k59_1768623_1	1249975.JQLP01000003_gene242	1.31e-11	62.8	COG2197@1|root,COG2197@2|Bacteria,4NN4B@976|Bacteroidetes,1I1MH@117743|Flavobacteriia,2P7I8@244698|Gillisia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1768623_2	1121931.AUHG01000011_gene2391	3.59e-64	201.0	COG3230@1|root,COG3230@2|Bacteria,4NQRJ@976|Bacteroidetes,1I4PE@117743|Flavobacteriia	976|Bacteroidetes	P	Heme oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Heme_oxygenase
k59_1259258_1	1123514.KB905902_gene304	5.87e-73	228.0	COG4625@1|root,COG4625@2|Bacteria,1N0QY@1224|Proteobacteria	1224|Proteobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16118_1	1121931.AUHG01000018_gene1387	3.61e-32	115.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_16118_2	411154.GFO_0297	5.15e-40	146.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_1089150_1	318167.Sfri_2985	1.02e-24	95.5	COG4238@1|root,COG4238@2|Bacteria,1PCXK@1224|Proteobacteria,1SY37@1236|Gammaproteobacteria,2QCB1@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Alanine-zipper, major outer membrane lipoprotein	-	-	-	ko:K06078	-	-	-	-	ko00000,ko01011	-	-	-	LPP
k59_16122_1	1086011.HJ01_01466	9.45e-150	432.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia,2NUTT@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1033716_1	946483.Cenrod_2241	6.95e-14	77.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,TarH
k59_638739_1	991.IW20_00185	6.99e-98	300.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1HYER@117743|Flavobacteriia,2NT9Q@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
k59_134214_1	572480.Arnit_2788	1.61e-41	153.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_D1,Cytochrome_C554,Cytochrome_C7,Lactonase
k59_1716937_1	317025.Tcr_0854	6.32e-96	302.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_1264328_2	1198232.CYCME_0297	3.51e-09	59.3	COG0226@1|root,COG0226@2|Bacteria,1N19C@1224|Proteobacteria,1SEQX@1236|Gammaproteobacteria,46336@72273|Thiotrichales	72273|Thiotrichales	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1202249_2	504487.JCM19302_609	3.87e-10	59.3	2EJ5Y@1|root,33CX5@2|Bacteria,4NYXR@976|Bacteroidetes,1I6IJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1202249_3	1484460.JSWG01000008_gene1937	5.16e-51	165.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia	976|Bacteroidetes	P	rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
k59_1202249_4	1178825.ALIH01000020_gene2718	1.77e-55	174.0	COG0607@1|root,COG0607@2|Bacteria,4NTEZ@976|Bacteroidetes,1I4AC@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_701193_1	1353528.DT23_02075	7.82e-123	368.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2XKUS@285107|Thioclava	28211|Alphaproteobacteria	I	Acetyl-CoA carboxylase	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_1322407_1	411154.GFO_3432	1.47e-121	348.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1HXN2@117743|Flavobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_1322407_2	555500.I215_00725	6.86e-15	72.4	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_1546056_1	1484460.JSWG01000001_gene2135	1.87e-23	101.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,1HXD0@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_1546056_2	1347342.BN863_13850	2.32e-16	77.8	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HXGY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_79175_1	1121931.AUHG01000010_gene29	7.33e-139	398.0	COG1893@1|root,COG1893@2|Bacteria,4NMFF@976|Bacteroidetes,1I3H3@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_586629_1	383372.Rcas_3262	4.19e-06	50.1	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,3776M@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_1546074_1	1286632.P278_15690	9.17e-90	277.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1HZGJ@117743|Flavobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1546074_2	504487.JCM19302_4166	6.64e-105	320.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia	976|Bacteroidetes	H	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1546075_1	411154.GFO_2899	0.000354	42.4	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1546075_2	411154.GFO_2898	1.74e-48	162.0	28HRC@1|root,2Z7YT@2|Bacteria,4NKDD@976|Bacteroidetes,1HYNI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_304757_1	1156937.MFUM_700127	2.73e-35	139.0	COG1067@1|root,COG1067@2|Bacteria,46YV9@74201|Verrucomicrobia,37G14@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	AAA domain	lonB	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_359897_1	563040.Saut_1471	2.59e-198	565.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1604832_1	985255.APHJ01000028_gene987	9.46e-13	67.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia,2P6DI@244698|Gillisia	976|Bacteroidetes	U	Sec-independent protein translocase protein (TatC)	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_1604832_2	1380600.AUYN01000003_gene49	4.53e-66	209.0	COG0794@1|root,COG2905@1|root,COG0794@2|Bacteria,COG2905@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_192129_1	572480.Arnit_0397	3.54e-85	273.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,43BS6@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	nirB	-	1.6.99.3,1.7.1.15	ko:K00362,ko:K03885	ko00190,ko00910,ko01120,map00190,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
k59_304758_1	435591.BDI_2467	1.34e-85	268.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,2FNQN@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
k59_81259_1	1348657.M622_14555	9.85e-90	268.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VJN5@28216|Betaproteobacteria,2KY5T@206389|Rhodocyclales	206389|Rhodocyclales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_81259_2	85643.Tmz1t_1376	7.06e-29	108.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VJA0@28216|Betaproteobacteria,2KXQ7@206389|Rhodocyclales	206389|Rhodocyclales	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_1548267_1	1168067.JAGP01000001_gene666	2.49e-182	522.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1435567_1	1121931.AUHG01000012_gene2818	1.76e-102	298.0	COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,1I1YB@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1435567_2	1453505.JASY01000028_gene352	3.09e-10	59.7	COG1413@1|root,COG1413@2|Bacteria,4NUQJ@976|Bacteroidetes,1I4DJ@117743|Flavobacteriia,2NW58@237|Flavobacterium	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1493392_1	1178825.ALIH01000003_gene2182	1.61e-87	271.0	COG3063@1|root,COG3063@2|Bacteria,4PM8F@976|Bacteroidetes,1IJMN@117743|Flavobacteriia	976|Bacteroidetes	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_19,TPR_8
k59_1493392_2	1178825.ALIH01000003_gene2183	2.78e-91	271.0	28IYJ@1|root,2Z8W9@2|Bacteria,4NJ8H@976|Bacteroidetes,1HZBS@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
k59_1493392_3	319236.JCM19294_1864	1.3e-90	270.0	29ZMS@1|root,30MNA@2|Bacteria,4NGT7@976|Bacteroidetes,1HZ2K@117743|Flavobacteriia,3HKIJ@363408|Nonlabens	976|Bacteroidetes	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
k59_1607208_1	411154.GFO_2527	4.07e-105	311.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_703734_1	1137281.D778_00610	1.45e-39	143.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_703734_2	1121912.AUHD01000001_gene2721	2.12e-29	108.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,1I24Y@117743|Flavobacteriia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_645940_1	1134474.O59_001710	3.32e-62	228.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3290@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,1NRP8@1224|Proteobacteria,1RWXK@1236|Gammaproteobacteria,1FFRE@10|Cellvibrio	1224|Proteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_1378793_1	1150469.RSPPHO_01424	7.47e-07	54.3	COG0438@1|root,COG0438@2|Bacteria,1PEWP@1224|Proteobacteria,2V82X@28211|Alphaproteobacteria,2JWA7@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k59_1203817_1	1121931.AUHG01000012_gene2928	3.75e-122	355.0	COG1052@1|root,COG1052@2|Bacteria,4NJGJ@976|Bacteroidetes,1HXQD@117743|Flavobacteriia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1378803_1	563040.Saut_1418	9.46e-18	76.3	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	cysZ	-	-	ko:K06203,ko:K07126	-	-	-	-	ko00000	-	-	-	DnaJ,Sel1
k59_1378803_2	929558.SMGD1_0031	4.24e-84	259.0	28K4S@1|root,2Z9TM@2|Bacteria,1N4AQ@1224|Proteobacteria,42PSN@68525|delta/epsilon subdivisions,2YMP7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_251152_1	1123514.KB905902_gene193	1.64e-76	253.0	COG2317@1|root,COG2317@2|Bacteria,1NNNJ@1224|Proteobacteria	1224|Proteobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_1096384_1	1121931.AUHG01000016_gene1067	5.23e-95	282.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1HXY3@117743|Flavobacteriia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
k59_1041057_1	1392490.JHZX01000001_gene1533	1.65e-146	417.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia	976|Bacteroidetes	HJ	Ribosomal protein S6 modification	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_476869_1	1442598.JABW01000035_gene1614	1.26e-39	155.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MV6@68525|delta/epsilon subdivisions,2YMMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal,NIT
k59_1719178_1	1123514.KB905899_gene1149	1.16e-28	114.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,45ZU3@72273|Thiotrichales	72273|Thiotrichales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_1719178_2	317025.Tcr_1559	7.44e-193	550.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,45ZRX@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_1719178_3	1123518.ARWI01000001_gene2400	5.48e-96	284.0	COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,4619U@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0149 family	-	-	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
k59_1719178_4	90813.JQMT01000001_gene1356	2.98e-35	121.0	COG3027@1|root,COG3027@2|Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_307008_1	323850.Shew_1647	2.37e-85	278.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q93Y@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_136574_1	1121931.AUHG01000011_gene1918	9.64e-98	290.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_979641_2	411154.GFO_1739	2.06e-122	351.0	COG0463@1|root,COG0463@2|Bacteria,4NFT2@976|Bacteroidetes,1HZ55@117743|Flavobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_362249_1	1565129.JSFF01000017_gene2960	8.22e-26	106.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria,2QBBP@267890|Shewanellaceae	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_927311_1	398767.Glov_0566	2.2e-40	154.0	COG0642@1|root,COG1352@1|root,COG0642@2|Bacteria,COG1352@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,PAS_7,PAS_9,Response_reg,dCache_1
k59_1378850_1	411154.GFO_2155	1.3e-10	59.3	COG0431@1|root,COG0431@2|Bacteria,4NNMA@976|Bacteroidetes,1I244@117743|Flavobacteriia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_1378850_2	1121931.AUHG01000011_gene2213	1.14e-56	183.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k59_1776312_1	526222.Desal_3312	6.13e-39	150.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2WJJ9@28221|Deltaproteobacteria,2M8RX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
k59_1378855_1	411154.GFO_0734	3.67e-157	458.0	COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,1HY3Y@117743|Flavobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
k59_476911_1	572480.Arnit_3078	1.06e-100	302.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_703868_1	411154.GFO_0502	1.52e-130	376.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1HXRB@117743|Flavobacteriia	976|Bacteroidetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Lipocalin_2
k59_703868_2	411154.GFO_0501	1.9e-30	112.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
k59_23234_1	326297.Sama_1709	4.1e-68	217.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,2Q95F@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM dehydrogenase, E1 component	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_23234_2	323850.Shew_1926	9.59e-39	137.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,2Q9V6@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM Transketolase central region	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_81416_1	1144275.COCOR_01728	2.31e-28	113.0	COG2850@1|root,COG2850@2|Bacteria,1MXD0@1224|Proteobacteria	1224|Proteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_757905_1	425104.Ssed_2820	6.04e-25	102.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,2Q9HX@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_1548417_1	1380600.AUYN01000010_gene839	1.46e-238	665.0	COG5492@1|root,COG5492@2|Bacteria,4NHPH@976|Bacteroidetes,1HZ96@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1548417_2	1380600.AUYN01000010_gene840	1.69e-137	403.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4NH8H@976|Bacteroidetes,1HYV1@117743|Flavobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	sprC	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_1493555_1	1380600.AUYN01000009_gene1825	2.76e-145	415.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_1493555_2	983544.Lacal_1879	2.64e-105	308.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia	976|Bacteroidetes	D	chromosome partitioning	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1435723_1	90814.KL370891_gene1601	8.79e-37	136.0	COG1577@1|root,COG1577@2|Bacteria,1NF04@1224|Proteobacteria	1224|Proteobacteria	I	mevalonate kinase	-	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1435723_2	90814.KL370891_gene1602	3.4e-51	173.0	COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_703907_2	1122225.AULQ01000005_gene2673	2e-73	226.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_362324_1	518766.Rmar_0001	3.53e-30	119.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1FITM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1096508_1	929558.SMGD1_1084	8.84e-91	279.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2YMCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iIT341.HP0476	tRNA-synt_1c
k59_1096508_2	929558.SMGD1_1137	1.09e-43	159.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_307103_1	709032.Sulku_2223	1e-19	86.3	COG1123@1|root,COG1123@2|Bacteria,1QXRI@1224|Proteobacteria,43CKN@68525|delta/epsilon subdivisions,2YTDT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k59_307103_2	1172190.M947_06250	6.65e-24	100.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2YN3A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_362343_1	1123518.ARWI01000001_gene1698	4.15e-46	164.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,4605W@72273|Thiotrichales	72273|Thiotrichales	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_871594_1	1121912.AUHD01000012_gene855	1.61e-39	142.0	COG4974@1|root,COG4974@2|Bacteria,4NX3Q@976|Bacteroidetes,1HXCN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_1776414_1	317025.Tcr_1778	1.04e-177	526.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,45ZY9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_81488_1	765913.ThidrDRAFT_3947	9.56e-71	220.0	28KEQ@1|root,2ZA0Y@2|Bacteria,1RBS9@1224|Proteobacteria,1RZ6X@1236|Gammaproteobacteria,1WXTH@135613|Chromatiales	135613|Chromatiales	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
k59_927416_1	999411.HMPREF1092_02125	6.76e-14	73.9	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,36EMS@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1776432_1	323850.Shew_3714	3.49e-84	273.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,2Q9N3@267890|Shewanellaceae	1236|Gammaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1548485_1	929558.SMGD1_0619	1.91e-27	112.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MV6@68525|delta/epsilon subdivisions,2YMMC@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,MCPsignal
k59_1548485_2	639282.DEFDS_1544	1.22e-19	92.4	COG0840@1|root,COG0840@2|Bacteria,2GEW0@200930|Deferribacteres	200930|Deferribacteres	NT	SMART chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal,dCache_3
k59_159521_1	1548151.LS70_05240	3.76e-18	84.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2YMKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_159521_2	1172190.M947_10265	5.02e-47	164.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1222659_1	1123037.AUDE01000024_gene1639	5.25e-73	227.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_782028_1	944547.ABLL_0362	1.25e-52	167.0	COG1393@1|root,COG1393@2|Bacteria,1QDI7@1224|Proteobacteria,42U8X@68525|delta/epsilon subdivisions,2YPXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_221265_2	400668.Mmwyl1_3535	8.59e-14	71.6	COG1879@1|root,COG1879@2|Bacteria,1MXJS@1224|Proteobacteria,1RRZV@1236|Gammaproteobacteria,1XN9Q@135619|Oceanospirillales	135619|Oceanospirillales	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
k59_897352_1	85643.Tmz1t_1992	4.48e-42	146.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,2KVI6@206389|Rhodocyclales	206389|Rhodocyclales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_897352_2	864051.BurJ1DRAFT_2805	3.45e-17	80.9	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,1KJY3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_1803600_1	1380600.AUYN01000001_gene2538	1.36e-30	117.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1803600_2	1380600.AUYN01000001_gene2537	1.24e-10	58.9	COG3296@1|root,COG3296@2|Bacteria,4NQGV@976|Bacteroidetes,1I2WN@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870,SHOCT
k59_1180440_1	1380600.AUYN01000009_gene962	8.26e-227	627.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1HX4Q@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_1180440_2	880070.Cycma_3307	9.2e-70	238.0	COG4928@1|root,COG4928@2|Bacteria,4NQ1W@976|Bacteroidetes,47V5B@768503|Cytophagia	976|Bacteroidetes	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
k59_1180440_3	1380600.AUYN01000009_gene964	2.13e-201	560.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_1180440_4	1392490.JHZX01000001_gene1355	2.31e-96	301.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1HXS7@117743|Flavobacteriia	976|Bacteroidetes	C	Malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_840107_1	572480.Arnit_0747	2.41e-168	476.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_503512_1	1380600.AUYN01000009_gene1256	6.53e-44	159.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1HZII@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
k59_673570_1	411154.GFO_2711	2.71e-263	726.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia	976|Bacteroidetes	CH	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_673570_2	1250278.JQNQ01000001_gene593	4.02e-28	107.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HXRV@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_613490_1	572480.Arnit_0606	7.7e-175	491.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2YN61@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_673579_1	376686.Fjoh_3902	4.27e-79	246.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,1HZ4R@117743|Flavobacteriia,2NYDE@237|Flavobacterium	976|Bacteroidetes	O	AIR synthase related protein, N-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_1180480_2	1121931.AUHG01000012_gene2874	1.04e-93	304.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_673586_1	411154.GFO_0540	0.0	1038.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
k59_673586_2	411154.GFO_0540	2.01e-43	156.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia	976|Bacteroidetes	DM	protein involved in exopolysaccharide biosynthesis	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
k59_334458_1	323850.Shew_2990	4.7e-49	172.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,2QAKB@267890|Shewanellaceae	1236|Gammaproteobacteria	H	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_334458_2	323850.Shew_2989	3.1e-11	62.4	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria,2QBTH@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_897406_1	1123393.KB891316_gene1970	7.53e-21	92.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,1KS4J@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_334464_1	1484460.JSWG01000009_gene527	1.18e-95	300.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_1574299_1	1537917.JU82_01570	5.28e-53	178.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2YNGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1574299_2	1150621.SMUL_0820	6.02e-38	129.0	2E63D@1|root,32SZ8@2|Bacteria,1N3BN@1224|Proteobacteria,42WAA@68525|delta/epsilon subdivisions,2YQCN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO	cowN	-	-	ko:K21694	-	-	-	-	ko00000	-	-	-	-
k59_840165_1	411154.GFO_1549	5.85e-12	63.2	COG0527@1|root,COG0527@2|Bacteria,4NJDY@976|Bacteroidetes,1HYZX@117743|Flavobacteriia	976|Bacteroidetes	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_840165_2	1121931.AUHG01000012_gene2618	5.4e-132	388.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1HYS5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1629787_1	411154.GFO_1772	9.3e-127	371.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_162888_1	1565129.JSFF01000009_gene1830	6.78e-109	326.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,2QA8A@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
k59_1006656_2	929558.SMGD1_2514	1.15e-134	392.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2YMMP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_732341_1	983545.Glaag_1995	5.4e-15	75.9	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,466EF@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_732341_2	506534.Rhein_1614	1.8e-32	123.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1WW1K@135613|Chromatiales	135613|Chromatiales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_1404575_1	1123234.AUKI01000017_gene2487	9.67e-148	422.0	28IN2@1|root,2Z8NI@2|Bacteria,4NK7J@976|Bacteroidetes,1I0W5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1404575_2	688270.Celal_1391	1.55e-78	237.0	2DPPF@1|root,332VS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1404575_4	179408.Osc7112_3964	2.27e-15	80.9	29Z27@1|root,30KZN@2|Bacteria,1G60Z@1117|Cyanobacteria,1HGSY@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1404575_5	688270.Celal_1394	3.98e-74	225.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR_1,TipAS
k59_897453_1	1304275.C41B8_13485	7.14e-07	52.8	COG2199@1|root,COG2199@2|Bacteria,1QU7H@1224|Proteobacteria,1T1PY@1236|Gammaproteobacteria	2|Bacteria	T	COG2199 FOG GGDEF domain	-	-	2.7.7.65	ko:K20958	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE4,GGDEF,dCache_1
k59_897453_2	1123518.ARWI01000001_gene1694	5.61e-113	331.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,460EZ@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k59_1006670_1	1172190.M947_02025	6.7e-86	269.0	COG4773@1|root,COG4773@2|Bacteria,1QZ1U@1224|Proteobacteria,42PHE@68525|delta/epsilon subdivisions,2YN5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1404591_1	411154.GFO_0107	1.97e-93	278.0	28QB8@1|root,2ZCTU@2|Bacteria,4NP7R@976|Bacteroidetes,1I1M5@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
k59_1404591_2	1121931.AUHG01000010_gene764	1.33e-170	477.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_557914_1	945713.IALB_1480	1.67e-67	225.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_1066177_1	1121931.AUHG01000010_gene442	5.41e-98	290.0	COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,1HY64@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
k59_557938_1	1380600.AUYN01000009_gene2061	8.12e-132	395.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_950687_1	929558.SMGD1_2757	1.97e-58	185.0	COG0500@1|root,COG2226@2|Bacteria,1Q99M@1224|Proteobacteria,43DPI@68525|delta/epsilon subdivisions,2YRRG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_950687_2	326298.Suden_1343	1.1e-113	332.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2YNYE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Hemolysin	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_446266_2	572480.Arnit_0927	2.19e-72	231.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_48638_2	90814.KL370891_gene611	1.05e-97	288.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,460Q6@72273|Thiotrichales	72273|Thiotrichales	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_1226347_1	1123514.KB905901_gene56	7.02e-44	149.0	COG3465@1|root,COG3465@2|Bacteria	2|Bacteria	-	-	-	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427,ko:K09388	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Macro,Methylase_S
k59_1293814_1	1123518.ARWI01000001_gene2422	4.64e-106	317.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,4604Z@72273|Thiotrichales	72273|Thiotrichales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_1293814_2	90814.KL370891_gene1304	8.12e-19	82.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales	72273|Thiotrichales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_108829_1	504487.JCM19302_879	9.02e-117	362.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1629836_1	402612.FP0902	1.74e-12	72.4	COG4783@1|root,COG4783@2|Bacteria,4NM0X@976|Bacteroidetes,1I0RP@117743|Flavobacteriia,2NXZE@237|Flavobacterium	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_1123949_1	1095769.CAHF01000013_gene3167	5.06e-16	75.9	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,474GS@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_1461708_1	1250232.JQNJ01000001_gene1494	1.81e-52	168.0	2C87H@1|root,32TKH@2|Bacteria,4NSZW@976|Bacteroidetes,1I4DX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_673734_1	709032.Sulku_0059	3.37e-34	124.0	COG1714@1|root,COG1714@2|Bacteria,1N2TA@1224|Proteobacteria	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_503678_1	62928.azo3627	1.89e-52	177.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VM6E@28216|Betaproteobacteria,2KV7Z@206389|Rhodocyclales	28216|Betaproteobacteria	M	Lytic transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_503680_2	90813.JQMT01000001_gene588	6.49e-46	153.0	2F2WS@1|root,33VSD@2|Bacteria,1NWN4@1224|Proteobacteria,1SPNS@1236|Gammaproteobacteria,462GM@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_503680_3	90813.JQMT01000001_gene589	3.87e-202	568.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,4600D@72273|Thiotrichales	72273|Thiotrichales	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1226397_1	1391428.V5KSE4_9CAUD	6.81e-71	222.0	4QCHF@10239|Viruses,4QW57@35237|dsDNA viruses  no RNA stage,4QPIH@28883|Caudovirales,4QHVS@10662|Myoviridae	10662|Myoviridae	S	PhoH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_446334_1	305700.B447_06095	2.58e-42	145.0	COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,2VNTX@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_446334_2	85643.Tmz1t_3635	6.44e-23	91.7	COG2246@1|root,COG2246@2|Bacteria,1N6ST@1224|Proteobacteria,2VWP6@28216|Betaproteobacteria,2KZ36@206389|Rhodocyclales	206389|Rhodocyclales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k59_840323_1	1385514.N782_12705	2.02e-18	88.6	COG3344@1|root,COG3344@2|Bacteria,1UZGS@1239|Firmicutes,4HIC9@91061|Bacilli	91061|Bacilli	L	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,Trypsin_2
k59_334644_1	323850.Shew_1245	1.61e-142	407.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,2Q96M@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1574456_1	1137281.D778_02738	2.13e-69	213.0	2A55H@1|root,30TUA@2|Bacteria,4NPTX@976|Bacteroidetes,1I26S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1574465_1	1123518.ARWI01000001_gene2212	2.02e-91	271.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1S24R@1236|Gammaproteobacteria,460K5@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_108903_1	326298.Suden_0066	4.08e-195	554.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2YMDG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
k59_732504_1	1380600.AUYN01000009_gene1324	8.9e-219	660.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2
k59_276064_1	1168067.JAGP01000001_gene1335	1.33e-36	132.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,45ZV0@72273|Thiotrichales	72273|Thiotrichales	M	NeuB family	-	-	2.5.1.101,2.5.1.56,2.5.1.97	ko:K01654,ko:K15898,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_276064_2	868131.MSWAN_1357	1.05e-14	74.7	COG2089@1|root,arCOG01050@2157|Archaea,2XTT7@28890|Euryarchaeota,23PJM@183925|Methanobacteria	183925|Methanobacteria	M	SAF	neuB	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_1293921_1	944547.ABLL_0029	6.74e-57	184.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_1293921_2	929558.SMGD1_0130	7.45e-81	253.0	COG4773@1|root,COG4773@2|Bacteria,1QZ1U@1224|Proteobacteria,42PHE@68525|delta/epsilon subdivisions,2YN5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_48752_1	572480.Arnit_0575	8.58e-118	340.0	COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,42TRD@68525|delta/epsilon subdivisions,2YPW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	hmm pf01810	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_48752_2	983328.AFGH01000030_gene563	2.09e-35	130.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2YMPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_785803_1	1353537.TP2_04345	2.53e-18	79.3	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria,2XN0N@285107|Thioclava	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
k59_785803_2	1353528.DT23_07760	2.62e-116	336.0	COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,2XMMT@285107|Thioclava	28211|Alphaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_48766_1	411154.GFO_1083	1.77e-112	330.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_517436_1	1121931.AUHG01000016_gene1109	6.25e-34	126.0	COG1413@1|root,COG1413@2|Bacteria,4NKV5@976|Bacteroidetes,1I03Q@117743|Flavobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_517436_2	411154.GFO_0836	9.09e-48	154.0	COG2204@1|root,COG2204@2|Bacteria,4NTIR@976|Bacteroidetes,1I4HX@117743|Flavobacteriia	976|Bacteroidetes	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_800542_1	504487.JCM19302_3078	7.08e-60	191.0	28V2E@1|root,2ZH5W@2|Bacteria,4NH6Z@976|Bacteroidetes,1I04G@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
k59_1364128_1	991.IW20_20205	1.62e-43	149.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5M@976|Bacteroidetes,1I10P@117743|Flavobacteriia,2NUSY@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
k59_1364128_2	1178825.ALIH01000001_gene2352	3.61e-26	101.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1HY9J@117743|Flavobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_179314_1	411154.GFO_0064	4.01e-220	621.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,1HX6A@117743|Flavobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein	mutS_2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
k59_347739_1	189425.PGRAT_08915	6.4e-12	65.9	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,4H9RS@91061|Bacilli,26VBR@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_347739_2	1121912.AUHD01000001_gene2488	6.93e-160	456.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1HXKY@117743|Flavobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_9104_1	985255.APHJ01000043_gene453	3.14e-82	259.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia,2P7BU@244698|Gillisia	976|Bacteroidetes	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
k59_1138578_1	458817.Shal_2061	1.01e-78	241.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,2QBSK@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_912926_1	1380600.AUYN01000007_gene3285	4.89e-133	397.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_461776_1	497321.C664_15768	2e-99	293.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2VN1E@28216|Betaproteobacteria,2KUEP@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_856225_1	317025.Tcr_0744	6.07e-92	289.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,4604H@72273|Thiotrichales	72273|Thiotrichales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1533955_1	980584.AFPB01000087_gene202	3.31e-36	131.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia,406SP@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_1533955_2	1392489.JPOL01000002_gene731	8.08e-123	363.0	COG2308@1|root,COG2308@2|Bacteria,4NFMN@976|Bacteroidetes,1HXQ6@117743|Flavobacteriia,2XISP@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_800591_1	90813.JQMT01000001_gene1224	3.1e-125	365.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,45ZN5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_347775_1	1123008.KB905718_gene3614	7.31e-67	226.0	2C2C5@1|root,2ZBHC@2|Bacteria,4NU14@976|Bacteroidetes,2FQDI@200643|Bacteroidia,22YI2@171551|Porphyromonadaceae	976|Bacteroidetes	S	hydrolase activity, acting on glycosyl bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_800592_1	292415.Tbd_1389	6.06e-102	314.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2VM8J@28216|Betaproteobacteria,1KSMZ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cupredoxin-like domain	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
k59_9139_1	94122.Shewana3_0775	1.49e-118	343.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,2QAHA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_405040_1	411154.GFO_2499	4.21e-207	582.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_347784_1	1123514.KB905902_gene288	6.09e-108	317.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,462SK@72273|Thiotrichales	72273|Thiotrichales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_347784_2	400668.Mmwyl1_0391	1.52e-32	122.0	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,1RRZY@1236|Gammaproteobacteria,1XHMR@135619|Oceanospirillales	135619|Oceanospirillales	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_1081845_2	1123518.ARWI01000001_gene1850	1.39e-164	463.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,45ZVE@72273|Thiotrichales	72273|Thiotrichales	S	polyphosphate kinase 2	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_1081845_3	90813.JQMT01000001_gene324	6e-102	302.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,460MC@72273|Thiotrichales	72273|Thiotrichales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1081845_4	1123518.ARWI01000001_gene1848	3.66e-82	256.0	COG3170@1|root,COG3170@2|Bacteria,1RHDN@1224|Proteobacteria,1RSHT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1591590_1	1123514.KB905899_gene733	6.51e-93	305.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,45ZUT@72273|Thiotrichales	72273|Thiotrichales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_1704088_2	317025.Tcr_0376	8.8e-98	299.0	COG2842@1|root,COG2842@2|Bacteria,1R9BD@1224|Proteobacteria,1SCZF@1236|Gammaproteobacteria,462I6@72273|Thiotrichales	1236|Gammaproteobacteria	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
k59_1591596_1	396588.Tgr7_1771	3.55e-39	136.0	COG5113@1|root,COG3236@2|Bacteria,1RK58@1224|Proteobacteria	1224|Proteobacteria	O	Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do. Helps maintain flavin levels. May act on other substrates in vivo. Has no activity against GTP, nucleoside monophosphates or ADP-ribose. Is Required for swarming motility	ybiA	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016798,GO:0016799,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901135,GO:1901360	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k59_1591596_2	1122201.AUAZ01000004_gene3393	1.3e-23	92.8	2D6Q2@1|root,32TMP@2|Bacteria,1N1TP@1224|Proteobacteria,1SS4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_291961_1	323850.Shew_0151	2.59e-136	421.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,2Q9YQ@267890|Shewanellaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1309288_1	929558.SMGD1_1041	5.46e-55	183.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	ptmE	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k59_1026522_1	1121931.AUHG01000020_gene3171	6.13e-118	343.0	COG4977@1|root,COG4977@2|Bacteria,4PKKC@976|Bacteroidetes,1IJBQ@117743|Flavobacteriia	976|Bacteroidetes	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18,HTH_AraC
k59_1026522_2	1121931.AUHG01000020_gene3169	7.58e-11	59.3	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,1I2TK@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
k59_1309290_1	391603.FBALC1_04402	0.000512	42.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I17E@117743|Flavobacteriia	976|Bacteroidetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_1081870_1	929558.SMGD1_2206	1.39e-107	328.0	2EPTW@1|root,33HED@2|Bacteria,1NK6N@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1364212_1	709032.Sulku_1289	1.5e-52	177.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2YNN6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cofactor biosynthesis protein NifE	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_1364212_2	709032.Sulku_1297	4.26e-120	355.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,42P89@68525|delta/epsilon subdivisions,2YN9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_856277_1	1565129.JSFF01000006_gene2519	2.59e-36	124.0	COG3529@1|root,COG3529@2|Bacteria,1N6RJ@1224|Proteobacteria,1SC9Y@1236|Gammaproteobacteria,2QCTU@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Probable metal-binding protein (DUF2387)	yheV	-	-	ko:K07070	-	-	-	-	ko00000	-	-	-	DUF2387
k59_66204_1	1123514.KB905899_gene736	4.18e-67	210.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,460E4@72273|Thiotrichales	72273|Thiotrichales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1647841_1	317025.Tcr_0558	2.6e-92	272.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,4610X@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_179417_1	929558.SMGD1_0746	2.73e-80	254.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1138663_1	1178825.ALIH01000005_gene130	6.69e-154	438.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1309309_1	411154.GFO_0394	1.23e-51	185.0	COG1345@1|root,COG1345@2|Bacteria,4NHMH@976|Bacteroidetes,1HZTE@117743|Flavobacteriia	976|Bacteroidetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
k59_1760866_1	411154.GFO_2980	1.51e-114	338.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_856309_1	572480.Arnit_1561	1.33e-45	167.0	COG2911@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2YMT2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
k59_347845_1	1172190.M947_06355	4.59e-20	88.2	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_630987_1	929558.SMGD1_2263	1.03e-47	161.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2YMQZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_406758_2	1121931.AUHG01000010_gene351	3.25e-102	296.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_123842_1	1121912.AUHD01000006_gene1222	5.8e-57	198.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_519295_1	1168067.JAGP01000001_gene844	8.72e-26	108.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,4603W@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_519295_2	1123514.KB905899_gene1078	7.99e-17	81.6	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,463KB@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k59_1083508_1	90814.KL370891_gene1068	2.15e-87	271.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales	72273|Thiotrichales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_67920_1	392500.Swoo_2979	4.24e-53	196.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,2QETZ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_914656_1	522306.CAP2UW1_0294	0.000109	45.8	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VIWA@28216|Betaproteobacteria,1KQ9A@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442,ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.4	-	-	MS_channel,TM_helix
k59_914656_2	563040.Saut_0074	7.05e-31	112.0	COG1547@1|root,COG1547@2|Bacteria,1PD94@1224|Proteobacteria,42WUE@68525|delta/epsilon subdivisions,2YQXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
k59_406776_1	1380600.AUYN01000009_gene1450	1.11e-94	280.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1HYQJ@117743|Flavobacteriia	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
k59_406776_2	1380600.AUYN01000003_gene200	7.73e-46	149.0	COG1826@1|root,COG1826@2|Bacteria,4NSAK@976|Bacteroidetes,1I40K@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_406776_3	1347342.BN863_27930	2.33e-96	303.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_745203_1	1123514.KB905899_gene1269	1.33e-95	283.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,4609V@72273|Thiotrichales	72273|Thiotrichales	P	TIGRFAM Nitrate transport ATP-binding	-	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
k59_745203_2	1123518.ARWI01000001_gene2326	3.04e-70	220.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,1RPP1@1236|Gammaproteobacteria,4600G@72273|Thiotrichales	72273|Thiotrichales	P	transporter, permease	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_914664_1	504487.JCM19302_302	8.47e-146	422.0	COG0415@1|root,COG0415@2|Bacteria,4NDW0@976|Bacteroidetes,1HWUN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phrB3	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_181159_1	1380600.AUYN01000009_gene1975	2.91e-196	553.0	COG2244@1|root,COG2244@2|Bacteria,4NI85@976|Bacteroidetes,1HXZ7@117743|Flavobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	wzxE	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_181159_2	436114.SYO3AOP1_1006	3.23e-09	62.8	COG0500@1|root,COG2226@2|Bacteria,2G4R6@200783|Aquificae	200783|Aquificae	H	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_519325_1	1123518.ARWI01000001_gene470	2.11e-25	97.4	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1S9GA@1236|Gammaproteobacteria,4631C@72273|Thiotrichales	72273|Thiotrichales	S	HIUase/Transthyretin family	-	-	-	-	-	-	-	-	-	-	-	-	Transthyretin
k59_1140272_1	1123228.AUIH01000001_gene1364	3.11e-82	271.0	COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XHSP@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
k59_970160_1	1178825.ALIH01000007_gene1733	1.71e-26	101.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_970160_2	1380600.AUYN01000009_gene1330	2.83e-51	174.0	2E4WE@1|root,32ZQI@2|Bacteria,4NURF@976|Bacteroidetes,1I5C9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1593488_1	1123514.KB905899_gene1372	5.92e-135	394.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,45ZT0@72273|Thiotrichales	72273|Thiotrichales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_576215_1	1132855.KB913035_gene2441	1.2e-35	131.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KKW1@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_576215_2	1042377.AFPJ01000015_gene1593	0.000281	41.2	COG5460@1|root,COG5460@2|Bacteria,1N7MS@1224|Proteobacteria,1SCTR@1236|Gammaproteobacteria,468GD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
k59_970176_1	655815.ZPR_3035	8.98e-91	280.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,1HY2E@117743|Flavobacteriia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
k59_1311104_1	1121931.AUHG01000011_gene2242	2.15e-176	503.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1311104_2	411154.GFO_2125	3.92e-46	159.0	2C57D@1|root,2Z7RS@2|Bacteria,4NEKN@976|Bacteroidetes,1HXT2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
k59_689821_1	317025.Tcr_0636	3.89e-92	277.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,46083@72273|Thiotrichales	72273|Thiotrichales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_689821_2	1123514.KB905899_gene583	6.06e-68	208.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,460NY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_1479839_1	391587.KAOT1_04530	1.89e-128	375.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1HZDU@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_1649548_1	1121931.AUHG01000018_gene1413	1e-117	356.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
k59_1762660_1	985255.APHJ01000019_gene744	5.75e-39	144.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia,2P5P9@244698|Gillisia	976|Bacteroidetes	P	Heavy-metal-associated domain	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_1762660_2	761193.Runsl_4712	2.47e-63	215.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_1140299_1	867900.Celly_1455	4.22e-99	297.0	28I9E@1|root,2Z8C2@2|Bacteria,4NFBW@976|Bacteroidetes,1HZK1@117743|Flavobacteriia,1F8BC@104264|Cellulophaga	976|Bacteroidetes	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
k59_576227_1	411154.GFO_0020	7.94e-36	132.0	COG2223@1|root,COG2223@2|Bacteria,4PMRK@976|Bacteroidetes,1IJXD@117743|Flavobacteriia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_576227_2	1168034.FH5T_19890	3.44e-67	211.0	2DN8B@1|root,32W2U@2|Bacteria,4P2T3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_802488_1	929558.SMGD1_2409	1.82e-110	336.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2YMNR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_349571_1	926556.Echvi_2142	6.23e-77	249.0	COG0547@1|root,COG0547@2|Bacteria,4P1C6@976|Bacteroidetes,47UH3@768503|Cytophagia	976|Bacteroidetes	E	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_349571_2	68170.KL590490_gene1265	0.000815	49.3	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
k59_349571_3	1380600.AUYN01000006_gene786	1.01e-271	756.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_1705982_2	1123228.AUIH01000005_gene640	6.65e-107	311.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1XJ6W@135619|Oceanospirillales	135619|Oceanospirillales	U	MotA TolQ ExbB proton channel	exbB1	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_463740_1	1250232.JQNJ01000001_gene2524	2.25e-69	222.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_362554_2	1380600.AUYN01000009_gene1210	5.24e-117	341.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1HXVM@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_704202_1	317025.Tcr_0783	3.57e-75	236.0	COG0225@1|root,COG0229@1|root,COG0526@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,COG0526@2|Bacteria,1MVUS@1224|Proteobacteria,1T0T1@1236|Gammaproteobacteria,460U4@72273|Thiotrichales	72273|Thiotrichales	CO	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR,Thioredoxin_2
k59_704202_2	1219065.VPR01S_01_02990	3.99e-60	199.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XWB0@135623|Vibrionales	135623|Vibrionales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,MscS_TM
k59_589239_1	1123518.ARWI01000001_gene1337	1.05e-104	310.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1096752_1	326298.Suden_0789	1.24e-104	315.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2YM9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0098	PALP,Thr_synth_N
k59_1096754_1	411154.GFO_2790	9.05e-121	349.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,1HY0B@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1266928_1	945713.IALB_2083	2.95e-29	120.0	COG0728@1|root,COG0728@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_1435982_2	1341181.FLJC2902T_23370	7.45e-29	108.0	2E0GD@1|root,32W2E@2|Bacteria,4NTTG@976|Bacteroidetes,1I3VK@117743|Flavobacteriia,2NWPR@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
k59_1435982_3	1380600.AUYN01000009_gene1614	3.91e-43	150.0	COG3794@1|root,COG3794@2|Bacteria,4NNXS@976|Bacteroidetes,1I3WK@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
k59_1379156_1	1565314.OA34_05190	7.6e-77	238.0	COG1403@1|root,COG1403@2|Bacteria,1RH6F@1224|Proteobacteria,42W1F@68525|delta/epsilon subdivisions,2YQN0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
k59_533152_1	90814.KL370891_gene1233	8.85e-74	223.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,4611D@72273|Thiotrichales	72273|Thiotrichales	C	Low-potential electron donor to a number of redox enzymes	-	-	-	ko:K03839,ko:K03840	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_533152_2	90814.KL370891_gene1234	6.34e-36	122.0	2EH2E@1|root,33AUC@2|Bacteria,1NI43@1224|Proteobacteria,1SWF1@1236|Gammaproteobacteria,463HA@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_533152_3	1123518.ARWI01000001_gene23	1.33e-89	267.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,460NS@72273|Thiotrichales	72273|Thiotrichales	V	N-acetylmuramoyl-L-alanine amidase	ampD	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k59_1204088_1	90814.KL370892_gene2235	4.91e-57	196.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria,460C0@72273|Thiotrichales	72273|Thiotrichales	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_646362_1	999541.bgla_1g33100	6.98e-20	89.7	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1K0B4@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_758242_1	1453498.LG45_05040	3.13e-16	75.9	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1HZ1F@117743|Flavobacteriia,2NSK7@237|Flavobacterium	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_758242_2	1434325.AZQN01000003_gene2808	1.08e-21	97.8	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,47NS6@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_362625_1	504487.JCM19302_3771	6.19e-122	372.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1IJ7E@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1153231_2	90814.KL370891_gene1741	2.16e-50	167.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,1S3KK@1236|Gammaproteobacteria,46150@72273|Thiotrichales	72273|Thiotrichales	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_1776725_1	411154.GFO_2682	4.26e-121	353.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1776725_2	1121931.AUHG01000011_gene1838	3.37e-24	95.9	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1I0RX@117743|Flavobacteriia	976|Bacteroidetes	M	serine threonine protein kinase	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
k59_1719590_1	1123518.ARWI01000001_gene468	7.18e-23	95.1	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,46248@72273|Thiotrichales	72273|Thiotrichales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
k59_1719590_2	1123518.ARWI01000001_gene469	7.8e-140	397.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,1RYXQ@1236|Gammaproteobacteria,463EQ@72273|Thiotrichales	72273|Thiotrichales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_1379226_1	411154.GFO_2961	4.73e-188	537.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_1267016_1	1123228.AUIH01000026_gene3880	1.35e-24	101.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XHZ3@135619|Oceanospirillales	135619|Oceanospirillales	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_1267016_2	1123228.AUIH01000026_gene3879	4.76e-89	271.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XHXX@135619|Oceanospirillales	135619|Oceanospirillales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_589337_1	1178825.ALIH01000005_gene166	2.4e-85	256.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1HY3J@117743|Flavobacteriia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
k59_81815_1	1123057.P872_07650	5.56e-71	223.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,47JFN@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_81815_2	1122179.KB890417_gene3265	3.44e-17	74.7	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL,SnoaL_2
k59_1325298_1	1469245.JFBG01000027_gene1495	2.07e-45	161.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1325298_2	991905.SL003B_2508	2.97e-18	78.6	COG4327@1|root,COG4327@2|Bacteria,1Q6E6@1224|Proteobacteria,2VCJN@28211|Alphaproteobacteria,4BR0S@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
k59_137044_1	1279017.AQYJ01000026_gene390	4.7e-54	192.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,465WE@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acsA	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_420324_1	1121931.AUHG01000011_gene1820	1.55e-36	136.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
k59_420324_2	411154.GFO_2931	4.58e-32	120.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1663302_1	523791.Kkor_0267	1.02e-25	98.2	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XKHD@135619|Oceanospirillales	135619|Oceanospirillales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_1663302_2	563040.Saut_0657	4e-145	424.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2YMA3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_758345_1	1380600.AUYN01000009_gene1570	4.03e-88	274.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1379287_1	1565129.JSFF01000028_gene693	1.4e-75	245.0	COG3221@1|root,COG4191@1|root,COG3221@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RYAB@1236|Gammaproteobacteria,2QAVU@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Phosphonate-bd
k59_1436130_1	1197477.IA57_04730	1.92e-46	152.0	2CH60@1|root,32S88@2|Bacteria,4NT1A@976|Bacteroidetes,1I3W8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_81850_1	563040.Saut_1629	3.44e-71	219.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2YN5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_81850_2	1172190.M947_02955	2.67e-37	126.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,42V3S@68525|delta/epsilon subdivisions,2YQ9B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
k59_1437807_2	1172190.M947_07700	1.59e-50	168.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2YN1K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1155125_2	745718.JADT01000011_gene735	1.63e-25	103.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HZNF@117743|Flavobacteriia	976|Bacteroidetes	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DUF3887,Hydrolase_4
k59_1043234_1	391603.FBALC1_06748	5.15e-113	327.0	COG0558@1|root,COG0558@2|Bacteria,4NHGH@976|Bacteroidetes,1HZ13@117743|Flavobacteriia	976|Bacteroidetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_1043234_2	1336803.PHEL49_0194	4.75e-96	290.0	28M39@1|root,2ZAHI@2|Bacteria,4NM3I@976|Bacteroidetes,1HYA9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_479122_1	497321.C664_16805	1.17e-82	265.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria,2KUWV@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1550538_1	317025.Tcr_1253	4.68e-49	159.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria,461F0@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
k59_1550538_2	1123514.KB905899_gene959	2.57e-55	185.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,460ZS@72273|Thiotrichales	72273|Thiotrichales	D	Peptidase family M23	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
k59_25351_1	1122201.AUAZ01000008_gene341	2.46e-27	119.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SZJR@1236|Gammaproteobacteria,469D7@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_706396_2	1121931.AUHG01000010_gene70	3.61e-164	485.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_873723_2	1123514.KB905899_gene435	2.74e-188	541.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,460B8@72273|Thiotrichales	72273|Thiotrichales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1495790_1	1380600.AUYN01000007_gene3227	3.21e-258	721.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_760136_1	1123037.AUDE01000015_gene2653	1.34e-58	200.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWZV@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Endonuclease_1,LTD
k59_706427_1	572480.Arnit_0249	1.89e-194	544.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YMUN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_1437870_1	991.IW20_03675	4.59e-100	301.0	COG0378@1|root,COG0378@2|Bacteria,4NJ0P@976|Bacteroidetes,1I0R0@117743|Flavobacteriia,2NYN2@237|Flavobacterium	976|Bacteroidetes	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_1437870_2	991.IW20_03670	9.89e-33	115.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes,1I565@117743|Flavobacteriia,2NZCT@237|Flavobacterium	976|Bacteroidetes	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_1268877_1	1123514.KB905899_gene1041	1.69e-111	342.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,45ZUV@72273|Thiotrichales	72273|Thiotrichales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_1778665_1	1347342.BN863_19860	9.63e-124	365.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_1778665_2	1380600.AUYN01000009_gene1123	7.43e-141	402.0	COG1349@1|root,COG1349@2|Bacteria,4NE7U@976|Bacteroidetes,1HZX7@117743|Flavobacteriia	976|Bacteroidetes	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k59_1778665_4	1121912.AUHD01000001_gene2857	2.65e-304	860.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_873757_1	1198232.CYCME_0104	2.12e-15	77.8	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,46225@72273|Thiotrichales	72273|Thiotrichales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_422113_1	1177179.A11A3_13415	1.4e-63	206.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate transporter	pitA	GO:0000041,GO:0003674,GO:0005215,GO:0005315,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006817,GO:0006820,GO:0006829,GO:0008150,GO:0008324,GO:0008509,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015654,GO:0015672,GO:0015698,GO:0015710,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1902600	-	ko:K03306,ko:K16322	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.1	-	iECABU_c1320.ECABU_c33930,iECO111_1330.ECO111_4301,iPC815.YPO3967	PHO4
k59_1665062_1	317025.Tcr_1046	2.28e-113	333.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4600E@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_253661_1	1121912.AUHD01000004_gene2206	2.59e-219	614.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1IJW9@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_253661_2	1121912.AUHD01000004_gene2205	9.64e-18	78.2	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1I30B@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxyl carrier protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
k59_591148_1	926692.AZYG01000097_gene2317	2.79e-45	169.0	COG0419@1|root,COG0419@2|Bacteria,1V0RJ@1239|Firmicutes,24EJF@186801|Clostridia	186801|Clostridia	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
k59_1268885_1	1380600.AUYN01000001_gene2671	6.58e-43	159.0	COG1345@1|root,COG1361@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_1268885_2	1178825.ALIH01000012_gene1779	4.43e-123	363.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia	976|Bacteroidetes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_1043309_1	326298.Suden_1201	3.47e-29	108.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,42U84@68525|delta/epsilon subdivisions,2YPVG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_1043309_2	929558.SMGD1_1848	5.91e-95	284.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_1778691_2	945713.IALB_2185	2.08e-66	221.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria	2|Bacteria	S	Nucleoside recognition	spmB	-	-	ko:K06373,ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
k59_818554_1	493475.GARC_3105	5.21e-43	160.0	COG0784@1|root,COG5001@1|root,COG0784@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria,1RRUX@1236|Gammaproteobacteria,465I9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k59_981692_1	1121931.AUHG01000011_gene2051	2.93e-88	280.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_981692_2	411154.GFO_2332	2.01e-169	478.0	COG1729@1|root,COG1729@2|Bacteria,4NQUS@976|Bacteroidetes,1I3H6@117743|Flavobacteriia	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_591194_1	1380600.AUYN01000009_gene1296	2.55e-151	446.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_591194_2	1380384.JADN01000007_gene1668	3.88e-47	156.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia	976|Bacteroidetes	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_479277_1	247633.GP2143_08749	8.16e-82	272.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1665147_1	1178825.ALIH01000001_gene2574	2.17e-136	389.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1HXJ3@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_1665147_2	504487.JCM19302_3131	1.24e-18	84.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1268975_1	572480.Arnit_2973	6.25e-139	417.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_1381088_1	90814.KL370891_gene733	2.01e-195	545.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,4608I@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1437984_2	1123326.JFBL01000001_gene1366	9.6e-27	110.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2YN0J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_1043398_1	929558.SMGD1_0093	1.38e-67	209.0	COG2230@1|root,COG2230@2|Bacteria,1QZ24@1224|Proteobacteria,43CEA@68525|delta/epsilon subdivisions,2YTBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	CMAS
k59_1001398_2	563040.Saut_1006	3.52e-26	100.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2YM7S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_608649_1	1380600.AUYN01000007_gene3136	4.76e-82	246.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes,1I2ET@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
k59_552728_2	706587.Desti_2499	6.68e-25	99.8	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2WQA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM multiple antibiotic resistance (MarC)-related protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_780074_1	1123514.KB905899_gene1478	1.24e-147	446.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM aminopeptidase N, Escherichia coli type	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1118721_1	751994.AGIG01000008_gene1086	1.78e-33	127.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1J4PE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1516061_1	572480.Arnit_1670	2.38e-60	191.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1516061_2	944547.ABLL_1568	1.9e-20	89.7	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2YMNU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_9
k59_216427_1	631362.Thi970DRAFT_02928	7.88e-110	342.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_836528_1	722419.PH505_do00100	1.14e-56	186.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,2Q0N5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_836528_2	1049564.TevJSym_bk00170	1.94e-45	160.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1J4FS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1030 Membrane-bound serine protease (ClpP class)	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
k59_43854_1	387093.SUN_0943	5.56e-92	292.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2YR2T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1400184_1	90814.KL370891_gene1492	4.14e-84	263.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1400184_2	1255043.TVNIR_3224	3.5e-09	55.1	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1WXGS@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_1741678_1	717773.Thicy_1077	1.78e-73	228.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,460DG@72273|Thiotrichales	72273|Thiotrichales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_218588_1	929558.SMGD1_2325	2.49e-52	177.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_1121002_1	1353528.DT23_08665	6.08e-92	275.0	COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,2TSDV@28211|Alphaproteobacteria,2XNDV@285107|Thioclava	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	kdgK	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_45781_1	1123514.KB905901_gene14	7.91e-31	115.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	chuZ	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx
k59_782495_1	1380600.AUYN01000001_gene2517	1.59e-113	337.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_554896_1	1515613.HQ37_06355	2.89e-23	102.0	COG3440@1|root,COG3440@2|Bacteria,4NT7F@976|Bacteroidetes,2FVGI@200643|Bacteroidia,2315N@171551|Porphyromonadaceae	976|Bacteroidetes	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
k59_554896_2	553218.CAMRE0001_0762	7.35e-33	120.0	COG0863@1|root,COG0863@2|Bacteria,1PCSR@1224|Proteobacteria,42QD4@68525|delta/epsilon subdivisions,2YNGJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
k59_105878_1	1197477.IA57_05395	5.12e-220	620.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_948098_1	1347342.BN863_8660	0.0	1448.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_948098_2	1178825.ALIH01000004_gene2943	2.28e-24	92.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1I50B@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k59_948098_3	1380600.AUYN01000009_gene1607	8.72e-116	333.0	28J86@1|root,2Z93E@2|Bacteria,4NJYR@976|Bacteroidetes,1I0EG@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_948098_4	1469557.JSWF01000025_gene1384	1.32e-10	60.8	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_1402017_1	90814.KL370891_gene597	2.54e-184	523.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,45ZZA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_670715_1	926562.Oweho_1399	6.91e-72	225.0	COG0451@1|root,COG0451@2|Bacteria,4NI4N@976|Bacteroidetes	976|Bacteroidetes	GM	NAD-dependent epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_670715_2	509635.N824_13560	1.93e-21	87.4	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1IQCJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_443379_1	411154.GFO_3378	7.1e-133	394.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_1628022_1	1121931.AUHG01000011_gene1751	2.6e-159	454.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_782539_1	388413.ALPR1_12160	7.45e-81	253.0	COG2321@1|root,COG2321@2|Bacteria,4NKTG@976|Bacteroidetes,47TU5@768503|Cytophagia	976|Bacteroidetes	S	neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_948115_1	90814.KL370891_gene1657	4.65e-205	596.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,45ZMZ@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_554938_1	1123367.C666_05145	5.79e-55	176.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,2KWWA@206389|Rhodocyclales	206389|Rhodocyclales	S	Tol-pal system-associated acyl-CoA thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k59_554938_2	1123367.C666_05140	3.24e-23	94.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,2KV8T@206389|Rhodocyclales	206389|Rhodocyclales	U	MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_1003705_1	1278309.KB907099_gene2709	2.08e-115	337.0	COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1S03A@1236|Gammaproteobacteria,1XN5X@135619|Oceanospirillales	135619|Oceanospirillales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1402053_1	1168067.JAGP01000001_gene121	4.69e-107	320.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_443414_1	1250005.PHEL85_1328	3.71e-15	76.3	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes,1I0BS@117743|Flavobacteriia	976|Bacteroidetes	S	5'-nucleotidase, lipoprotein e(P4) family	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
k59_610692_1	1442598.JABW01000005_gene637	1.88e-06	53.9	2APR0@1|root,31EUU@2|Bacteria,1QC6P@1224|Proteobacteria,42Y16@68525|delta/epsilon subdivisions,2YQWD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
k59_555018_1	1137281.D778_00157	4.3e-28	109.0	2ECPJ@1|root,336MC@2|Bacteria,4NWR8@976|Bacteroidetes,1I4TU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4738
k59_555018_2	1178825.ALIH01000015_gene1873	3.84e-63	209.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_331551_1	944546.ABED_1872	1.04e-151	434.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_331551_2	944547.ABLL_2526	7.76e-14	67.8	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2YNX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_1800881_1	929558.SMGD1_2549	5.64e-93	285.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2YMJ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mur ligase middle domain	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1290896_2	709032.Sulku_1778	2.82e-70	223.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,42NEF@68525|delta/epsilon subdivisions,2YTM5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
k59_1349781_1	1565129.JSFF01000001_gene870	4.67e-139	415.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,2QAPP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	torA	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009033,GO:0009061,GO:0009322,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016657,GO:0032991,GO:0044237,GO:0045333,GO:0055114,GO:1902494	1.7.2.3	ko:K07811	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding,TAT_signal
k59_273482_1	326298.Suden_1269	1.3e-18	84.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_273482_2	326298.Suden_0621	3.67e-89	269.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42PYD@68525|delta/epsilon subdivisions,2YN6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k59_1063508_1	323850.Shew_2766	5.95e-135	394.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,2QAKS@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
k59_838112_1	326298.Suden_1875	4.68e-29	109.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2YNQD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_838112_2	326298.Suden_1876	1.65e-35	132.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1290926_1	62928.azo1202	5.56e-117	341.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,2KU8H@206389|Rhodocyclales	206389|Rhodocyclales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k59_729420_1	563040.Saut_1834	5.05e-103	298.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2YMUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_555082_1	1237149.C900_02768	5.1e-38	139.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_555082_2	1123057.P872_02220	6.75e-46	157.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_500867_1	945713.IALB_0487	1.16e-38	148.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
k59_1744064_1	929558.SMGD1_0755	2.7e-86	263.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_948252_1	1121931.AUHG01000011_gene1628	1.65e-97	291.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1HX6B@117743|Flavobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_948252_2	411154.GFO_2899	7.88e-116	342.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1121208_2	90814.KL370891_gene918	2.89e-26	97.8	29750@1|root,2ZUD0@2|Bacteria,1P8GT@1224|Proteobacteria,1SVP4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1121208_3	1123517.JOMR01000001_gene1050	2.96e-36	129.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,460E4@72273|Thiotrichales	72273|Thiotrichales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1003851_1	946077.W5A_08187	1.63e-56	186.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_1349844_1	305700.B447_20206	1.77e-125	370.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,2KVA8@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_1572012_1	929558.SMGD1_1352	1.03e-109	322.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2YNUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_782743_1	1121931.AUHG01000011_gene1956	7.25e-87	262.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1HWT4@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
k59_443558_2	273121.WS0211	1.97e-08	57.0	2DI3R@1|root,301Y2@2|Bacteria,1PU5N@1224|Proteobacteria,42ZHI@68525|delta/epsilon subdivisions,2YRPK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1290967_2	1453505.JASY01000011_gene4052	3.28e-102	306.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1HYHF@117743|Flavobacteriia,2NUAS@237|Flavobacterium	976|Bacteroidetes	M	lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_610817_2	398767.Glov_1642	6.6e-24	98.2	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k59_1402199_1	90814.KL370891_gene700	1.2e-136	398.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,46053@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM ATPase, FliI YscN family	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1744130_1	1565129.JSFF01000015_gene107	1.63e-110	338.0	COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria,2Q97A@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TIGRFAM TonB-dependent siderophore receptor	fhuE	-	-	ko:K16088	-	-	-	-	ko00000,ko02000	1.B.14.1.10,1.B.14.1.3,1.B.14.1.8	-	-	Plug,TonB_dep_Rec
k59_1628151_1	1380600.AUYN01000007_gene3241	2.84e-85	277.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_160175_2	563040.Saut_1514	2.76e-35	128.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2YP9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_331686_1	929558.SMGD1_1105	3.01e-63	208.0	COG1538@1|root,COG1538@2|Bacteria,1Q5ZE@1224|Proteobacteria,42V2A@68525|delta/epsilon subdivisions,2YQ6A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1518576_1	1492737.FEM08_03820	3.97e-46	156.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1HX7K@117743|Flavobacteriia,2NYBN@237|Flavobacterium	976|Bacteroidetes	IQ	PRINTS Short-chain dehydrogenase reductase (SDR) superfamily signature	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_1518594_1	1392490.JHZX01000001_gene2108	1.68e-70	237.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_1458992_1	491952.Mar181_0260	0.000394	48.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XJF8@135619|Oceanospirillales	135619|Oceanospirillales	NT	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_670992_2	945713.IALB_1263	2.13e-32	120.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_1572090_1	326298.Suden_0505	2.9e-30	108.0	COG0776@1|root,COG0776@2|Bacteria,1QQYR@1224|Proteobacteria,42V36@68525|delta/epsilon subdivisions,2YQA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the bacterial histone-like protein family	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_799951_2	1137281.D778_00259	9.98e-12	61.6	COG0219@1|root,COG0219@2|Bacteria,4NNTD@976|Bacteroidetes,1I1JC@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_347187_1	323850.Shew_1933	1.44e-102	306.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria,2QA6J@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Endonuclease exonuclease phosphatase	yafD	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1308604_1	1123514.KB905903_gene405	1.65e-85	263.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,4607Y@72273|Thiotrichales	72273|Thiotrichales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1308604_2	1123514.KB905903_gene404	2.81e-39	139.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4601Z@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_687239_1	411154.GFO_1767	2.99e-32	118.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_912355_2	1123518.ARWI01000001_gene1420	7.78e-61	201.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,461XX@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_404411_1	944547.ABLL_0088	3.62e-159	457.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2YNF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_1308615_2	1178825.ALIH01000010_gene457	2.98e-65	206.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1HXBH@117743|Flavobacteriia	976|Bacteroidetes	I	Phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
k59_687248_1	926559.JoomaDRAFT_0760	3.26e-81	252.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_968437_1	983544.Lacal_0303	8.31e-67	225.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_404416_1	411154.GFO_0638	6.76e-85	253.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1I1G2@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_404416_2	411154.GFO_0639	4.61e-16	75.5	COG0346@1|root,COG0346@2|Bacteria,4NQSP@976|Bacteroidetes,1I1G3@117743|Flavobacteriia	976|Bacteroidetes	E	ring-cleavage extradiol dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_1192651_1	411154.GFO_3128	6.79e-67	206.0	COG3187@1|root,COG3187@2|Bacteria,4NQIA@976|Bacteroidetes,1I5JP@117743|Flavobacteriia	976|Bacteroidetes	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4377,META
k59_1192651_2	411154.GFO_3127	4.67e-93	272.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_1192651_4	1121931.AUHG01000010_gene102	2.54e-102	298.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1I1A5@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
k59_799979_1	1123518.ARWI01000001_gene1950	9.66e-123	358.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,460EG@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_799979_2	1123518.ARWI01000001_gene1951	5.98e-28	111.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,45ZYC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_291328_1	1123518.ARWI01000001_gene2012	3.69e-38	145.0	2AAYF@1|root,33UXF@2|Bacteria,1NVAX@1224|Proteobacteria,1SN6E@1236|Gammaproteobacteria,4627W@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_291328_2	1278309.KB907100_gene2092	5.71e-67	214.0	COG0463@1|root,COG0463@2|Bacteria,1RFXT@1224|Proteobacteria,1S5PY@1236|Gammaproteobacteria,1XP92@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyltransferase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
k59_742877_2	1453503.AU05_25260	2.82e-23	101.0	COG0419@1|root,COG0419@2|Bacteria,1Q6FJ@1224|Proteobacteria,1S0MC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23
k59_347214_1	90814.KL370891_gene1635	3.91e-184	523.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,45ZW6@72273|Thiotrichales	72273|Thiotrichales	J	ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1647199_1	296591.Bpro_0387	8.44e-27	103.0	COG0625@1|root,COG0625@2|Bacteria,1MW27@1224|Proteobacteria,2W0TF@28216|Betaproteobacteria,4AG60@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
k59_1647199_2	390235.PputW619_1090	2.84e-33	127.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the glutamate synthase family	HA62_33250	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1760213_1	1270193.JARP01000001_gene2601	3.56e-15	80.9	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,2NT4M@237|Flavobacterium	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
k59_799986_1	411154.GFO_2852	2.27e-24	97.4	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1HX8Z@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_799986_2	411154.GFO_2853	2.71e-46	155.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,1HXF0@117743|Flavobacteriia	976|Bacteroidetes	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_799986_3	411154.GFO_2854	6.45e-88	269.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_1590954_1	1298593.TOL_2672	1.79e-134	390.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1XHCW@135619|Oceanospirillales	135619|Oceanospirillales	E	Periplasmic binding protein domain	-	-	-	ko:K01999,ko:K11959	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_1363627_1	298386.PBPRB0486	1.5e-18	93.6	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS,PAS_3,PAS_9,dCache_1
k59_1477285_1	1380384.JADN01000008_gene1057	5.46e-07	50.8	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1HY28@117743|Flavobacteriia	976|Bacteroidetes	H	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1477285_2	391603.FBALC1_01312	1.09e-147	434.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_235312_1	1380600.AUYN01000001_gene2434	1.34e-91	269.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_630369_1	1249975.JQLP01000005_gene2620	9.53e-148	442.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2P5GQ@244698|Gillisia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1533414_1	1123228.AUIH01000011_gene2129	6.7e-44	152.0	COG1744@1|root,COG1744@2|Bacteria,1NGHH@1224|Proteobacteria,1T1CE@1236|Gammaproteobacteria,1XIXE@135619|Oceanospirillales	135619|Oceanospirillales	S	PFAM Basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
k59_347258_1	1178825.ALIH01000002_gene989	5.1e-34	127.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_347258_2	1484460.JSWG01000015_gene1172	2.94e-84	254.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,1HZ0N@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_630386_1	1453500.AT05_08595	5.03e-67	211.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1HYEY@117743|Flavobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_742931_1	563040.Saut_1422	9.85e-07	49.7	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2YQ2W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
k59_1251125_1	398579.Spea_3618	2.07e-19	81.6	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,2QBM4@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k59_1251125_2	425104.Ssed_0725	1.14e-56	176.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,2QC5N@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	yhbH	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_291387_1	1165841.SULAR_05053	2.76e-150	430.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2YNBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_516960_1	1353528.DT23_05845	2.96e-66	203.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2U945@28211|Alphaproteobacteria,2XNAU@285107|Thioclava	28211|Alphaproteobacteria	S	Secondary thiamine-phosphate synthase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_516960_2	1353528.DT23_05840	2.32e-23	91.7	2EQHY@1|root,33I3Y@2|Bacteria,1NNAM@1224|Proteobacteria,2UMYW@28211|Alphaproteobacteria,2XNNU@285107|Thioclava	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1760275_1	572480.Arnit_0212	1.72e-100	308.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM Alpha amylase, catalytic	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_1025996_1	1434325.AZQN01000012_gene3680	7.93e-287	794.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_1138146_1	425104.Ssed_0753	1.13e-26	103.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,2Q8K7@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_121732_1	326298.Suden_0863	1.8e-94	283.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1363692_1	572480.Arnit_0031	2.64e-172	493.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_404511_1	865937.Gilli_2966	7.26e-83	261.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,1HY7X@117743|Flavobacteriia,2P7CC@244698|Gillisia	976|Bacteroidetes	U	Fibronectin type 3 domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
k59_855708_1	1178825.ALIH01000002_gene905	1.83e-87	267.0	COG2017@1|root,COG2017@2|Bacteria,4NKUK@976|Bacteroidetes,1I13Q@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_855708_2	1250006.JHZZ01000001_gene2364	0.0	887.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HXMU@117743|Flavobacteriia,3VVUQ@52959|Polaribacter	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_1363699_1	944547.ABLL_1677	8.31e-57	178.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,42TNM@68525|delta/epsilon subdivisions,2YPUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	alkylphosphonate uptake protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k59_1363699_2	944547.ABLL_1952	3.58e-36	129.0	COG2207@1|root,COG2207@2|Bacteria,1QYD9@1224|Proteobacteria,43CBM@68525|delta/epsilon subdivisions,2YNP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_AraC
k59_1533481_1	641143.HMPREF9331_02217	9.97e-21	92.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia,1EQWI@1016|Capnocytophaga	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1420963_1	1089547.KB913013_gene751	3.21e-07	56.6	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NKEB@976|Bacteroidetes,47K74@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
k59_121755_1	411154.GFO_0296	5.75e-59	185.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_121755_2	1121931.AUHG01000018_gene1388	2.49e-64	215.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1647304_1	1168067.JAGP01000001_gene65	1.11e-219	634.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462IM@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_235413_1	563040.Saut_1645	9.99e-18	82.8	COG1317@1|root,COG1317@2|Bacteria,1NJAJ@1224|Proteobacteria,42P5I@68525|delta/epsilon subdivisions,2YQ57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k59_235413_2	929558.SMGD1_0745	1.73e-55	182.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,42MS3@68525|delta/epsilon subdivisions,2YM90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliG	GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_517039_1	269798.CHU_1985	5.34e-62	204.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,47M04@768503|Cytophagia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
k59_1026051_1	1123517.JOMR01000001_gene119	4.05e-58	189.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,461Y4@72273|Thiotrichales	72273|Thiotrichales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1026051_2	317025.Tcr_1065	4.84e-159	471.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,461S8@72273|Thiotrichales	72273|Thiotrichales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_1420996_2	317025.Tcr_1406	4.1e-39	134.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,4619W@72273|Thiotrichales	72273|Thiotrichales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k59_1420996_3	1123518.ARWI01000001_gene456	1.07e-84	250.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,460PC@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_573930_1	90814.KL370891_gene433	1.75e-106	318.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,45ZNK@72273|Thiotrichales	72273|Thiotrichales	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_573930_2	740709.A10D4_07735	6.57e-41	145.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,2QFG9@267893|Idiomarinaceae	1236|Gammaproteobacteria	NU	Twitching motility protein PilT	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1477402_1	172045.KS04_17945	1.54e-54	175.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1I2C0@117743|Flavobacteriia,34PYB@308865|Elizabethkingia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
k59_1477402_2	1094980.Mpsy_1901	4.46e-50	162.0	COG3832@1|root,arCOG05261@2157|Archaea,2Y3Q0@28890|Euryarchaeota	28890|Euryarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_65723_1	1123518.ARWI01000001_gene999	1.09e-68	222.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,460Y5@72273|Thiotrichales	72273|Thiotrichales	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_1421005_1	317025.Tcr_0733	2.27e-94	281.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,460EY@72273|Thiotrichales	72273|Thiotrichales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1421005_2	1123518.ARWI01000001_gene412	0.0	944.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales	72273|Thiotrichales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_347373_1	357804.Ping_1764	2.95e-28	115.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_178952_1	1121931.AUHG01000010_gene585	3.69e-201	566.0	COG0651@1|root,COG0651@2|Bacteria,4NGBC@976|Bacteroidetes,1HZAC@117743|Flavobacteriia	976|Bacteroidetes	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_347402_1	929558.SMGD1_2072	3.49e-61	203.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_3,PAS_9,Response_reg
k59_121839_1	326298.Suden_0897	2.64e-58	198.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2YMP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_121839_2	944547.ABLL_1265	1.7e-37	129.0	COG3613@1|root,COG3613@2|Bacteria,1N0AK@1224|Proteobacteria	1224|Proteobacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	2.4.2.6	ko:K08728	ko00240,map00240	-	R02806	RC00063	ko00000,ko00001,ko01000	-	-	-	Nuc_deoxyrib_tr
k59_1647394_1	903818.KI912269_gene271	3.53e-17	83.2	COG1352@1|root,COG1352@2|Bacteria,3Y4GP@57723|Acidobacteria	57723|Acidobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_1647394_2	563040.Saut_0976	3.22e-32	125.0	COG0835@1|root,COG4566@1|root,COG0835@2|Bacteria,COG4566@2|Bacteria,1N81M@1224|Proteobacteria,42TBG@68525|delta/epsilon subdivisions,2YPER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1308847_1	1238450.VIBNISOn1_1210007	3.06e-93	281.0	COG1638@1|root,COG1638@2|Bacteria,1NJX4@1224|Proteobacteria,1RQF6@1236|Gammaproteobacteria,1XVVY@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_575649_1	1336803.PHEL49_0902	2.96e-36	132.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HZ86@117743|Flavobacteriia,3VX1M@52959|Polaribacter	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1479199_1	572480.Arnit_0137	8.76e-93	280.0	COG0679@1|root,COG0679@2|Bacteria,1N5NC@1224|Proteobacteria,42PYE@68525|delta/epsilon subdivisions,2YMUI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1663677_2	85643.Tmz1t_1676	1.62e-69	217.0	2CD04@1|root,300W7@2|Bacteria,1RGKT@1224|Proteobacteria,2VRUM@28216|Betaproteobacteria,2KWFG@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1097304_1	1565129.JSFF01000030_gene2838	3.36e-65	206.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,2Q9UP@267890|Shewanellaceae	1236|Gammaproteobacteria	F	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_589789_1	1178825.ALIH01000002_gene964	1.94e-67	227.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,4PM99@976|Bacteroidetes,1IJNC@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg,Y_Y_Y
k59_477776_1	411154.GFO_0187	2.84e-77	249.0	COG0810@1|root,COG0810@2|Bacteria,4PKAV@976|Bacteroidetes,1HWXW@117743|Flavobacteriia	976|Bacteroidetes	M	Gliding motility protein RemB	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_477776_2	1121931.AUHG01000010_gene841	2.8e-22	92.8	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1HXXM@117743|Flavobacteriia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_533668_1	90814.KL370891_gene1614	1e-132	394.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,46100@72273|Thiotrichales	72273|Thiotrichales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_195373_1	929558.SMGD1_2428	1.21e-77	248.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_980269_1	1137281.D778_02481	1.8e-77	252.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1325742_2	1123514.KB905899_gene1704	3.07e-78	237.0	COG4232@1|root,COG4232@2|Bacteria,1N90P@1224|Proteobacteria,1SFPD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_1325742_4	56110.Oscil6304_2815	2.92e-07	59.3	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
k59_928192_1	1172190.M947_04465	1.49e-58	193.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_928192_2	1172190.M947_04470	1.35e-23	99.8	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,42NCG@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_1041957_1	929558.SMGD1_0681	2.79e-51	181.0	COG2199@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5278@2|Bacteria,1QYKE@1224|Proteobacteria	1224|Proteobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GGDEF
k59_1663710_1	90814.KL370891_gene1627	1.43e-43	160.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,460CP@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_477793_1	1123518.ARWI01000001_gene1236	1.5e-45	166.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,4600P@72273|Thiotrichales	72273|Thiotrichales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_589811_1	572480.Arnit_0785	3.96e-125	379.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_82279_1	768671.ThimaDRAFT_4175	2.82e-86	280.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_307920_1	1442598.JABW01000030_gene1378	9.99e-36	135.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,42PA6@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
k59_758793_1	1380600.AUYN01000002_gene4	7.08e-73	246.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_1549278_1	1137281.D778_01901	6.94e-141	406.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1HXG0@117743|Flavobacteriia	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k59_1549284_1	367737.Abu_0145	3.83e-05	44.7	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_1549284_2	1442598.JABW01000002_gene1755	1.75e-49	167.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,42TDF@68525|delta/epsilon subdivisions,2YP4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Mannosyl-glycoprotein	-	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
k59_1720127_1	754476.Q7A_355	1.98e-61	202.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,461KB@72273|Thiotrichales	72273|Thiotrichales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1720127_2	666685.R2APBS1_2115	2.97e-176	522.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,1X3S2@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	-	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
k59_817151_1	1392490.JHZX01000001_gene1586	1.06e-78	259.0	28IHD@1|root,2Z8IK@2|Bacteria,4NF9V@976|Bacteroidetes,1HY20@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
k59_817151_2	1380600.AUYN01000006_gene672	9.44e-170	476.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1HXJZ@117743|Flavobacteriia	976|Bacteroidetes	G	synthase	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
k59_817151_3	504487.JCM19302_3900	2.24e-133	385.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_817151_4	504487.JCM19302_3899	5.29e-74	222.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1I1ZA@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_363211_1	929558.SMGD1_1765	1.8e-57	197.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1QU1X@1224|Proteobacteria	1224|Proteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K02480,ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,dCache_2,sCache_2
k59_704943_1	1353528.DT23_00200	4.99e-31	108.0	2ADC4@1|root,3131N@2|Bacteria,1PRMD@1224|Proteobacteria,2V3WE@28211|Alphaproteobacteria,2XNQ0@285107|Thioclava	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_704943_2	1353528.DT23_00195	2.47e-63	207.0	2BWZZ@1|root,2Z7V7@2|Bacteria,1PFGK@1224|Proteobacteria,2TUWA@28211|Alphaproteobacteria,2XMUB@285107|Thioclava	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
k59_1663762_1	62928.azo1554	4.25e-117	346.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,2KVDB@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_477849_1	1168067.JAGP01000001_gene1143	1.98e-109	317.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,1RPQV@1236|Gammaproteobacteria,460QG@72273|Thiotrichales	72273|Thiotrichales	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_533737_1	1197477.IA57_10465	6.11e-100	296.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_533737_2	1178825.ALIH01000005_gene194	6.51e-194	540.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1HWM5@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_252279_1	1123514.KB905900_gene2133	6.35e-10	58.9	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,461V9@72273|Thiotrichales	72273|Thiotrichales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
k59_252279_2	1168067.JAGP01000001_gene1369	9.86e-76	232.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria,4609V@72273|Thiotrichales	72273|Thiotrichales	P	TIGRFAM Nitrate transport ATP-binding	-	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
k59_1379772_2	929558.SMGD1_1319	8.46e-58	180.0	COG0607@1|root,COG0607@2|Bacteria,1Q1NN@1224|Proteobacteria,42U2F@68525|delta/epsilon subdivisions,2YQ1E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_363262_1	1123514.KB905900_gene2081	3.14e-139	400.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,45ZVG@72273|Thiotrichales	72273|Thiotrichales	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1494542_1	1121007.AUML01000024_gene338	9.44e-123	369.0	arCOG10304@1|root,30WUR@2|Bacteria,4NGAA@976|Bacteroidetes,1HZC7@117743|Flavobacteriia,2YGWM@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1494542_2	1380600.AUYN01000001_gene2275	1.58e-155	453.0	COG2244@1|root,COG2244@2|Bacteria,4NHYC@976|Bacteroidetes,1HWN7@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_195494_1	1476902.A0A067ZJ24_9CAUD	4.1e-95	287.0	4QBU2@10239|Viruses,4QV13@35237|dsDNA viruses  no RNA stage,4QPH3@28883|Caudovirales,4QJBY@10662|Myoviridae	10662|Myoviridae	S	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_195494_2	1268068.PG5_42530	4.17e-40	147.0	COG0640@1|root,COG0640@2|Bacteria,1NGAG@1224|Proteobacteria,1SSEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
k59_420887_1	1492738.FEM21_10030	3.91e-159	469.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NUYS@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_758928_1	1178825.ALIH01000007_gene1716	3.38e-111	328.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1HXQX@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1153939_1	234267.Acid_5651	2.3e-41	150.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_1153947_1	1380600.AUYN01000001_gene2342	4.18e-89	280.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
k59_195539_1	90814.KL370891_gene720	6.82e-73	239.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,4608D@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1720254_1	1123228.AUIH01000003_gene873	1.65e-60	210.0	COG1196@1|root,COG1196@2|Bacteria,1QUTY@1224|Proteobacteria,1T351@1236|Gammaproteobacteria,1XHM7@135619|Oceanospirillales	135619|Oceanospirillales	D	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
k59_195550_1	504487.JCM19302_1196	2.79e-128	382.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,1HXR0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k59_82456_1	929558.SMGD1_0877	3.44e-131	390.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_363351_1	1123514.KB905899_gene568	2.93e-55	179.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,460K8@72273|Thiotrichales	72273|Thiotrichales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_1204573_1	929558.SMGD1_2770	7.81e-44	149.0	2AJ5J@1|root,319Q6@2|Bacteria,1Q3I6@1224|Proteobacteria,42XD0@68525|delta/epsilon subdivisions,2YR0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1494638_1	323850.Shew_1726	2.72e-62	196.0	COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,1SCXK@1236|Gammaproteobacteria,2QB11@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein LuxR	-	-	-	ko:K04333	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GerE
k59_1777475_1	326298.Suden_0310	1.8e-06	49.7	COG0204@1|root,COG0204@2|Bacteria,1QAEF@1224|Proteobacteria,42YDI@68525|delta/epsilon subdivisions,2YREE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1777475_2	563040.Saut_0853	7.2e-137	393.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2YNZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_1777475_3	1172190.M947_07305	1.04e-19	85.9	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,42ZGY@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_1720308_1	1123326.JFBL01000007_gene632	5.14e-82	270.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_478022_1	1168067.JAGP01000001_gene149	1.45e-114	360.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales	72273|Thiotrichales	E	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1326007_1	563040.Saut_1823	9.48e-133	394.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_1042202_1	1172190.M947_03545	5.35e-106	322.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2YMAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1267748_1	411154.GFO_2132	2.6e-118	351.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1HYB7@117743|Flavobacteriia	976|Bacteroidetes	G	alpha amylase, catalytic	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
k59_1267748_2	985255.APHJ01000030_gene2433	3.88e-178	513.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia,2P7GY@244698|Gillisia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208,ko:K21575	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_26528_2	1380600.AUYN01000006_gene701	9.98e-68	222.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,1HZ2A@117743|Flavobacteriia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1156425_1	1121931.AUHG01000018_gene1375	4.61e-95	294.0	COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,1HWTJ@117743|Flavobacteriia	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_197887_1	90814.KL370891_gene1676	1.31e-39	142.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,4601Y@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the GARS family	purD	-	6.3.2.6,6.3.4.13	ko:K01945,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N,SAICAR_synt
k59_197887_2	1168067.JAGP01000001_gene1753	1.26e-215	605.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,46009@72273|Thiotrichales	72273|Thiotrichales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_649438_1	1229276.DI53_1704	4.07e-59	197.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1IQGD@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_1156440_1	1124780.ANNU01000036_gene44	1.71e-52	182.0	28ID4@1|root,2Z8FC@2|Bacteria,4NFYZ@976|Bacteroidetes,47NAT@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_536145_1	497321.C664_03902	8.12e-96	290.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,2KVG7@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_1099894_1	1278309.KB907108_gene1621	5.29e-83	265.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHS3@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg
k59_930676_1	768670.Calni_0577	6.63e-17	81.3	COG2865@1|root,COG2865@2|Bacteria,2GG04@200930|Deferribacteres	200930|Deferribacteres	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,TrmB
k59_930676_2	103690.17133739	5.36e-41	147.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k59_26558_1	411154.GFO_1475	2.31e-70	222.0	COG1196@1|root,COG1196@2|Bacteria,4NIJ6@976|Bacteroidetes,1HZCG@117743|Flavobacteriia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26558_2	1121931.AUHG01000012_gene2690	2.56e-75	249.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_365768_1	317025.Tcr_1017	1.19e-40	136.0	28Y6I@1|root,2ZK1V@2|Bacteria,1PBMK@1224|Proteobacteria,1SV11@1236|Gammaproteobacteria,463F0@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_254920_1	688270.Celal_1389	3.49e-117	350.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia,1F8P5@104264|Cellulophaga	976|Bacteroidetes	P	COGs COG0471 Di- and tricarboxylate transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_26574_1	929558.SMGD1_2315	1.68e-110	323.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2YMFH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_84839_1	1565314.OA34_10305	4.52e-14	84.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PPF@68525|delta/epsilon subdivisions,2YRRN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140090_1	929558.SMGD1_1057	7.39e-100	312.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_26578_1	70448.Q0P3F1	2.23e-52	178.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,34JUG@3041|Chlorophyta	3041|Chlorophyta	C	Cytochrome C and Quinol oxidase polypeptide I	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k59_1666233_2	1123518.ARWI01000001_gene2114	1.41e-188	534.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,45ZR5@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1174793_1	1121931.AUHG01000018_gene1350	2.57e-13	68.2	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia	976|Bacteroidetes	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_497964_1	1121931.AUHG01000016_gene947	7.19e-83	255.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1HWPX@117743|Flavobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_608197_1	929558.SMGD1_1730	4.92e-29	109.0	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_608197_2	929558.SMGD1_1725	5.14e-74	233.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_1118170_1	1380600.AUYN01000009_gene1360	2.32e-165	473.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1220231_1	504487.JCM19302_2176	3.09e-77	236.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1I1DS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k59_1060706_1	62928.azo2591	4.61e-166	488.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,2VJWF@28216|Betaproteobacteria,2KY3E@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1174850_1	1380600.AUYN01000003_gene236	4.37e-07	51.2	2EFU3@1|root,339K7@2|Bacteria,4NY7Q@976|Bacteroidetes,1I6UJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_328704_1	1453505.JASY01000019_gene4769	1.9e-70	238.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJTY@117743|Flavobacteriia,2NSV7@237|Flavobacterium	976|Bacteroidetes	H	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_1118223_1	411154.GFO_1565	2.86e-32	117.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_1118223_2	1121931.AUHG01000012_gene2611	4.17e-164	482.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HY5H@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_1456344_1	1249997.JHZW01000003_gene2851	6.91e-43	152.0	COG2207@1|root,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1HX7J@117743|Flavobacteriia,2PI2I@252356|Maribacter	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
k59_1456344_2	1121875.KB907548_gene1505	7.69e-57	179.0	COG2346@1|root,COG2346@2|Bacteria,4NSU1@976|Bacteroidetes,1I4A6@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1456344_3	485916.Dtox_4336	3.99e-40	134.0	2C82G@1|root,32RK9@2|Bacteria,1VZ8X@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
k59_1174877_1	1211813.CAPH01000003_gene1275	1.12e-20	92.4	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,2FMMX@200643|Bacteroidia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1174877_2	1128421.JAGA01000003_gene2746	8.59e-09	55.5	COG0447@1|root,COG0447@2|Bacteria,2NPGH@2323|unclassified Bacteria	2|Bacteria	H	Enoyl-CoA hydratase/isomerase	menB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1798042_1	1270193.JARP01000003_gene1965	1.3e-62	205.0	COG0438@1|root,COG0438@2|Bacteria,4PPF4@976|Bacteroidetes,1IKKG@117743|Flavobacteriia,2NT2D@237|Flavobacterium	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_103195_1	326298.Suden_1822	1.45e-86	278.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
k59_1000990_1	243233.MCA3005	2.63e-61	211.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XFC7@135618|Methylococcales	135618|Methylococcales	L	DNA RNA helicase, superfamily II	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
k59_1060751_1	317025.Tcr_2037	3.29e-42	151.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,463UV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.5.1	ko:K05922	-	-	-	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_1060751_2	317025.Tcr_2036	3.05e-59	187.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,1S4H2@1236|Gammaproteobacteria,4638H@72273|Thiotrichales	72273|Thiotrichales	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_215982_1	1202962.KB907156_gene3194	2.63e-18	86.7	COG2244@1|root,COG2244@2|Bacteria,1R6GF@1224|Proteobacteria,1RZZ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_215982_2	929558.SMGD1_2413	6e-49	157.0	2BR7U@1|root,32K64@2|Bacteria,1Q2P2@1224|Proteobacteria,431JX@68525|delta/epsilon subdivisions,2YSDV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_383693_1	1121931.AUHG01000011_gene2407	1.42e-73	223.0	2985A@1|root,2ZVB7@2|Bacteria,4NNTB@976|Bacteroidetes,1I0QR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4494
k59_383693_2	411154.GFO_0853	1.17e-92	280.0	COG0596@1|root,COG0596@2|Bacteria,4NZUP@976|Bacteroidetes,1HZ6I@117743|Flavobacteriia	976|Bacteroidetes	S	Releases the N-terminal proline from various substrates	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_552325_1	1526927.Plano_2215	3.48e-66	211.0	COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli,26EQ7@186818|Planococcaceae	91061|Bacilli	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
k59_328758_1	292459.STH2163	3.79e-28	118.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia	186801|Clostridia	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_103229_1	929558.SMGD1_0809	1.43e-67	229.0	COG2198@1|root,COG2198@2|Bacteria,1PCKH@1224|Proteobacteria,42W9Z@68525|delta/epsilon subdivisions,2YQ6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43444_1	411154.GFO_2765	1.03e-110	329.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_216015_1	1236542.BALM01000001_gene187	9.65e-40	133.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,2QC8D@267890|Shewanellaceae	1236|Gammaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_1001043_1	1565129.JSFF01000004_gene3100	2.65e-63	201.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,2Q94R@267890|Shewanellaceae	1236|Gammaproteobacteria	KO	PFAM cobalamin synthesis protein P47K	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_608344_2	400668.Mmwyl1_1169	6.01e-87	266.0	COG0462@1|root,COG0462@2|Bacteria,1R5PV@1224|Proteobacteria,1RQRB@1236|Gammaproteobacteria,1XN1C@135619|Oceanospirillales	135619|Oceanospirillales	EF	pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
k59_1569619_2	572480.Arnit_2825	1.94e-78	236.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42RJM@68525|delta/epsilon subdivisions,2YP5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k59_668118_1	1121931.AUHG01000015_gene1304	2.32e-125	377.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_1347057_1	563040.Saut_0120	1.8e-69	213.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC4@68525|delta/epsilon subdivisions,2YMGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_1456439_1	563040.Saut_0565	1.77e-162	468.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2YMY6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_1515706_1	760154.Sulba_1574	6.33e-91	279.0	COG0270@1|root,COG0270@2|Bacteria,1R59Y@1224|Proteobacteria,42Z5R@68525|delta/epsilon subdivisions,2YRE6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_1798182_1	746697.Aeqsu_0193	2.84e-62	195.0	COG1525@1|root,COG1525@2|Bacteria,4NT0S@976|Bacteroidetes,1I47N@117743|Flavobacteriia	976|Bacteroidetes	L	nuclease	lpxP	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
k59_328859_1	572480.Arnit_2268	1.04e-61	206.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PF9@68525|delta/epsilon subdivisions,2YNH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_328859_2	572480.Arnit_2267	2.65e-89	265.0	COG0847@1|root,COG0847@2|Bacteria,1QA0P@1224|Proteobacteria,42RPG@68525|delta/epsilon subdivisions,2YPAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1741264_1	1168067.JAGP01000001_gene837	2.91e-24	100.0	COG2199@1|root,COG3706@2|Bacteria,1QVPY@1224|Proteobacteria,1T2GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
k59_1741264_2	870187.Thini_3750	6.09e-62	195.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,460YE@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
k59_608410_1	1392490.JHZX01000001_gene2108	3.18e-132	412.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_271226_1	572480.Arnit_1241	1.81e-123	381.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,42M05@68525|delta/epsilon subdivisions,2YNMZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_1347121_1	1353528.DT23_01790	3.74e-112	331.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,2XMC9@285107|Thioclava	28211|Alphaproteobacteria	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1060896_2	497321.C664_15728	3.36e-137	397.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria,2KY20@206389|Rhodocyclales	206389|Rhodocyclales	S	COG3436 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_726764_1	945713.IALB_0374	2.2e-26	107.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
k59_726764_2	4536.ONIVA09G14510.1	2.97e-16	79.3	COG0144@1|root,KOG1122@2759|Eukaryota,37M5F@33090|Viridiplantae,3GFZD@35493|Streptophyta,3KQFQ@4447|Liliopsida,3IAZ1@38820|Poales	35493|Streptophyta	A	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
k59_328902_1	1453498.LG45_06180	1.48e-128	382.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia,2NT7V@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208,ko:K21575	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_1572117_2	1168067.JAGP01000001_gene203	2.57e-12	63.9	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,45ZXZ@72273|Thiotrichales	72273|Thiotrichales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_443670_2	929558.SMGD1_0099	7.23e-45	150.0	2A1M6@1|root,30PVA@2|Bacteria,1QTJ9@1224|Proteobacteria,42VDW@68525|delta/epsilon subdivisions,2YQIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_948405_1	1236541.BALL01000016_gene2312	0.000123	42.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,2QAN1@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	ompR	GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_948405_2	1565129.JSFF01000023_gene2814	4.3e-79	236.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,2QA15@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_555277_1	1565129.JSFF01000009_gene1799	1.3e-58	187.0	COG2165@1|root,COG2165@2|Bacteria,1RK2J@1224|Proteobacteria,1RYF2@1236|Gammaproteobacteria,2Q8QE@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	mshB	-	-	ko:K10925	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
k59_671058_1	1125863.JAFN01000001_gene232	6.55e-29	115.0	COG1225@1|root,COG1225@2|Bacteria,1N3ZR@1224|Proteobacteria,42TQK@68525|delta/epsilon subdivisions,2WQSX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_1402328_1	411154.GFO_1654	3.08e-164	491.0	COG4258@1|root,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
k59_1121393_1	1121931.AUHG01000001_gene3104	5.14e-62	196.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia	976|Bacteroidetes	N	gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_1121393_2	1121896.JMLU01000033_gene2832	2.12e-06	47.0	COG2329@1|root,COG2329@2|Bacteria,4PKDD@976|Bacteroidetes,1IJ84@117743|Flavobacteriia,2NWQZ@237|Flavobacterium	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_1572156_1	983544.Lacal_2226	8.78e-131	389.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,1HWVE@117743|Flavobacteriia	976|Bacteroidetes	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_1572156_2	1380600.AUYN01000009_gene2136	3.09e-206	577.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-lyase	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_218977_1	929558.SMGD1_1770	5.1e-07	50.1	COG0745@1|root,COG0745@2|Bacteria,1PFKD@1224|Proteobacteria,42TIQ@68525|delta/epsilon subdivisions,2YPWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_218977_2	929558.SMGD1_1771	5.98e-25	94.4	2AK15@1|root,31AQQ@2|Bacteria,1Q5Z2@1224|Proteobacteria,43242@68525|delta/epsilon subdivisions,2YSUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_218977_3	929558.SMGD1_1773	2.74e-64	198.0	COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,42TW9@68525|delta/epsilon subdivisions,2YPY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_1121400_1	998674.ATTE01000001_gene3480	1.78e-29	116.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,4602X@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1572163_1	326298.Suden_1330	4.58e-64	204.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2YMSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iIT341.HP0961	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1572163_2	929558.SMGD1_2325	2.54e-17	80.9	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_218983_1	1565129.JSFF01000002_gene3604	2.39e-112	348.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,2Q9PC@267890|Shewanellaceae	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_729649_2	929558.SMGD1_0192	8.99e-112	346.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42NJQ@68525|delta/epsilon subdivisions,2YMZP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	hmm pf00563	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_1402365_1	640081.Dsui_0541	6.97e-27	107.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,2VIDF@28216|Betaproteobacteria,2KUAV@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_1402365_2	1144325.PMI22_02384	1.83e-54	181.0	COG0079@1|root,COG0079@2|Bacteria,1MXDP@1224|Proteobacteria,1RR2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin	cobC	-	2.6.1.9	ko:K00817,ko:K02225	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026,M00122	R00694,R00734,R03243,R06529,R07302	RC00006,RC00090,RC00096,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1223598_1	385682.AFSL01000053_gene469	1.3e-93	297.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,2FN30@200643|Bacteroidia,3XJVM@558415|Marinilabiliaceae	976|Bacteroidetes	F	Ribonucleotide reductase, barrel domain	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1744311_1	1237149.C900_02372	1.21e-22	98.2	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia	976|Bacteroidetes	NU	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_1518758_1	1123517.JOMR01000001_gene420	6.07e-14	70.5	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,461KC@72273|Thiotrichales	72273|Thiotrichales	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1518758_2	1123518.ARWI01000001_gene1830	7.77e-65	199.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,460XZ@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_273745_1	411154.GFO_2734	9.99e-114	338.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_948479_1	1121931.AUHG01000011_gene2387	1.6e-48	161.0	COG0345@1|root,COG0345@2|Bacteria,4NGIG@976|Bacteroidetes,1HYXN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_948479_2	411154.GFO_1962	7.93e-172	481.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,1HXDB@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_948479_3	1121931.AUHG01000011_gene2385	2.35e-197	553.0	COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,1HX2Y@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1004082_1	1565129.JSFF01000036_gene1446	1.61e-24	101.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MUAK@1224|Proteobacteria,1RPDY@1236|Gammaproteobacteria,2QA03@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	cpxA	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007155,GO:0007165,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0022610,GO:0023014,GO:0023052,GO:0031224,GO:0031589,GO:0035556,GO:0036211,GO:0042710,GO:0042802,GO:0043170,GO:0043412,GO:0043708,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0044764,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0090605,GO:0140096,GO:1901564	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CpxA_peri,HAMP,HATPase_c,HisKA
k59_1004082_2	1565129.JSFF01000036_gene1445	2.75e-67	209.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,2Q9KR@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	cpxR	GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010810,GO:0019219,GO:0019222,GO:0030155,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07662,ko:K19610	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_729704_1	1429916.X566_17565	2.24e-35	130.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,2TVKU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	ATPase of the PP-loop superfamily implicated in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,NAD_synthase,PAPS_reduct
k59_729704_2	1244531.CIG1485E_0060	1.85e-62	208.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YN3Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_783011_1	1221522.B723_11435	5.23e-67	227.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1YR4T@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Cation transporting ATPase, C-terminus	ctpF	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_783032_1	1172190.M947_09760	1.93e-125	370.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2YN28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_895101_1	84531.JMTZ01000033_gene271	7.58e-38	141.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1X334@135614|Xanthomonadales	135614|Xanthomonadales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_1291237_1	572480.Arnit_2380	4.8e-44	162.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria	2|Bacteria	T	Single Cache domain 2	-	-	2.7.13.3	ko:K03406,ko:K13040	ko02020,ko02030,map02020,map02030	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	EAL,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3,dCache_2
k59_1530418_2	1380600.AUYN01000009_gene1814	4.12e-264	737.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1HWX8@117743|Flavobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_965931_1	1392489.JPOL01000002_gene329	1.06e-19	80.9	2DU79@1|root,33P7B@2|Bacteria,4P44U@976|Bacteroidetes,1I9VR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_344130_1	945713.IALB_0585	2.9e-76	248.0	COG0557@1|root,COG0557@2|Bacteria	2|Bacteria	K	exoribonuclease II activity	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_1473996_1	1123008.KB905718_gene3614	7.1e-164	485.0	2C2C5@1|root,2ZBHC@2|Bacteria,4NU14@976|Bacteroidetes,2FQDI@200643|Bacteroidia,22YI2@171551|Porphyromonadaceae	976|Bacteroidetes	S	hydrolase activity, acting on glycosyl bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1644022_1	1380600.AUYN01000007_gene3211	0.0	1325.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,1HWRT@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k59_1644022_2	1380600.AUYN01000007_gene3210	2.22e-56	176.0	COG2329@1|root,COG2329@2|Bacteria,4NS8X@976|Bacteroidetes,1I3WG@117743|Flavobacteriia	976|Bacteroidetes	S	involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_1644022_3	1380600.AUYN01000007_gene3249	0.0	2724.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1HYCE@117743|Flavobacteriia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k59_513652_1	425104.Ssed_2298	3.57e-120	357.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,2Q988@267890|Shewanellaceae	1236|Gammaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_231969_1	1121931.AUHG01000011_gene2235	9.44e-92	290.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_852374_1	929558.SMGD1_2215	7.36e-157	447.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,42MJ1@68525|delta/epsilon subdivisions,2YMZ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0212	M20_dimer,Peptidase_M20
k59_344149_1	709032.Sulku_1307	1.53e-153	460.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,42YPK@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_627195_1	929558.SMGD1_0465	1.41e-73	237.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2YMF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Polysaccharide biosynthesis protein	pglF	-	4.2.1.135	ko:K15912	ko00520,map00520	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_683996_1	1163617.SCD_n01606	1.08e-90	294.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1700335_1	1380600.AUYN01000007_gene3346	8.27e-172	489.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,1HYIN@117743|Flavobacteriia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_570563_1	317025.Tcr_0327	5.41e-54	173.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,460QZ@72273|Thiotrichales	72273|Thiotrichales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_570563_2	90814.KL370891_gene265	5.28e-97	296.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,4601P@72273|Thiotrichales	72273|Thiotrichales	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1247797_1	1408473.JHXO01000001_gene1972	2.66e-238	683.0	COG2133@1|root,COG3391@1|root,COG3511@1|root,COG2133@2|Bacteria,COG3391@2|Bacteria,COG3511@2|Bacteria,4NER2@976|Bacteroidetes,2FQ0E@200643|Bacteroidia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1247797_2	1406840.Q763_09515	4.79e-118	337.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,1I1ZI@117743|Flavobacteriia	976|Bacteroidetes	FJ	deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_1247797_3	1406840.Q763_09520	0.0	885.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,4NGFJ@976|Bacteroidetes,1HZVM@117743|Flavobacteriia,2NX0W@237|Flavobacterium	976|Bacteroidetes	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
k59_1305401_1	1123514.KB905902_gene294	1.66e-20	86.3	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,46182@72273|Thiotrichales	72273|Thiotrichales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_1305401_2	90814.KL370892_gene2240	3.88e-112	328.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,460YK@72273|Thiotrichales	72273|Thiotrichales	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_5527_1	1484460.JSWG01000009_gene122	6.39e-38	139.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
k59_5527_2	1123037.AUDE01000001_gene1691	6.44e-62	201.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,1HWTA@117743|Flavobacteriia	976|Bacteroidetes	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_1190574_1	1121931.AUHG01000010_gene754	8.7e-81	252.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1190574_2	1250278.JQNQ01000001_gene2167	1.8e-28	114.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1417854_1	762903.Pedsa_1427	1.69e-103	321.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1IPEK@117747|Sphingobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_739986_1	929558.SMGD1_0877	1.2e-148	435.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_1644044_1	504487.JCM19302_1464	3.92e-31	117.0	COG1360@1|root,COG1360@2|Bacteria,4NHDJ@976|Bacteroidetes,1HWS7@117743|Flavobacteriia	976|Bacteroidetes	N	flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1644044_2	1484460.JSWG01000004_gene2562	0.0	1160.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_1644044_3	1380600.AUYN01000007_gene3341	3.68e-226	630.0	COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,1HXMY@117743|Flavobacteriia	976|Bacteroidetes	P	PFAM Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1644044_4	391603.FBALC1_15587	1.43e-52	168.0	COG2849@1|root,COG2849@2|Bacteria,4NS8U@976|Bacteroidetes,1I41J@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k59_1644044_5	1392490.JHZX01000001_gene1440	1.61e-169	486.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1IJEZ@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1644044_6	1137281.D778_02073	1.01e-155	468.0	COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,4PKRK@976|Bacteroidetes,1IJDQ@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
k59_401308_2	1123518.ARWI01000001_gene689	1.54e-89	265.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,460ZQ@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_401308_3	317025.Tcr_1592	1.65e-211	588.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,45ZTK@72273|Thiotrichales	72273|Thiotrichales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_401308_4	1123514.KB905899_gene1500	1.26e-66	209.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,461G2@72273|Thiotrichales	72273|Thiotrichales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k59_401308_5	317025.Tcr_1590	2.04e-112	346.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1758670_2	1123228.AUIH01000014_gene330	5.79e-85	260.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria,1XI5T@135619|Oceanospirillales	135619|Oceanospirillales	ET	Amino acid ABC transporter substrate-binding protein	aapJ	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k59_1531964_1	317025.Tcr_0852	1.73e-121	353.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,45ZP5@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1531964_2	317025.Tcr_0851	4.01e-17	77.4	COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,1RXZV@1236|Gammaproteobacteria,461UE@72273|Thiotrichales	72273|Thiotrichales	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_1475709_1	926550.CLDAP_18090	8.48e-88	271.0	COG1653@1|root,COG1653@2|Bacteria,2G958@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
k59_177211_1	1406840.Q763_13485	4.93e-83	266.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NEWJ@976|Bacteroidetes,1HZA6@117743|Flavobacteriia,2P051@237|Flavobacterium	976|Bacteroidetes	MU	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14
k59_345740_1	1282361.ABAC402_00770	1.99e-44	177.0	COG2374@1|root,COG2931@1|root,COG5492@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,COG5492@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2KJ0K@204458|Caulobacterales	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_M10_C
k59_685698_1	572480.Arnit_2071	9.52e-95	295.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2YMXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter, ATP-binding protein	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1475725_1	1168034.FH5T_14935	1.44e-54	191.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,2FWMX@200643|Bacteroidia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
k59_515357_1	990073.ATHU01000001_gene836	3.22e-71	231.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1079812_1	1121035.AUCH01000007_gene465	2.46e-48	164.0	COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VRSF@28216|Betaproteobacteria,2KXAZ@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1079812_2	317025.Tcr_0412	2.46e-29	110.0	COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,1RR4T@1236|Gammaproteobacteria,46116@72273|Thiotrichales	72273|Thiotrichales	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_685706_1	1121912.AUHD01000001_gene2800	5.9e-29	111.0	COG1629@1|root,COG1629@2|Bacteria,4PKUT@976|Bacteroidetes,1IJFW@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_7091_1	1123037.AUDE01000015_gene2598	1.13e-278	835.0	COG1345@1|root,COG1361@1|root,COG2866@1|root,COG3227@1|root,COG3420@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG2866@2|Bacteria,COG3227@2|Bacteria,COG3420@2|Bacteria,4NHMH@976|Bacteroidetes	976|Bacteroidetes	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
k59_854107_1	1392489.JPOL01000002_gene1192	3.91e-220	617.0	COG1395@1|root,COG1395@2|Bacteria,4PMVM@976|Bacteroidetes,1IKA9@117743|Flavobacteriia	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1249534_1	1379698.RBG1_1C00001G0287	1.91e-22	100.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_402947_1	1380600.AUYN01000010_gene841	9.84e-67	223.0	COG1196@1|root,COG3064@1|root,COG1196@2|Bacteria,COG3064@2|Bacteria,4NGJZ@976|Bacteroidetes,1HY5X@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	sprD	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF,SPOR
k59_402947_2	1380600.AUYN01000010_gene840	3.29e-75	239.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4NH8H@976|Bacteroidetes,1HYV1@117743|Flavobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	sprC	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_1249536_2	1123514.KB905899_gene840	3.67e-45	151.0	2A49J@1|root,30SV1@2|Bacteria,1RF7U@1224|Proteobacteria,1S3TV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1136682_1	391587.KAOT1_06217	3.16e-13	68.9	COG0438@1|root,COG0438@2|Bacteria,4NE53@976|Bacteroidetes,1HX83@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_1136682_2	1122225.AULQ01000007_gene2258	5.73e-122	356.0	COG1216@1|root,COG1216@2|Bacteria,4NFEP@976|Bacteroidetes,1HWUH@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_1758725_1	1380600.AUYN01000001_gene2277	4.82e-176	497.0	COG3774@1|root,COG3774@2|Bacteria,4NITG@976|Bacteroidetes,1I139@117743|Flavobacteriia	976|Bacteroidetes	M	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
k59_572282_1	768671.ThimaDRAFT_4696	8.59e-66	219.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,1RQRW@1236|Gammaproteobacteria,1WWNC@135613|Chromatiales	135613|Chromatiales	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k59_1531990_1	317025.Tcr_0726	1.73e-251	698.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,4608H@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1531990_2	317025.Tcr_0725	1.29e-202	565.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,45ZTF@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1531990_3	90814.KL370891_gene872	4.45e-68	216.0	2AVH6@1|root,31M9J@2|Bacteria,1RHYF@1224|Proteobacteria,1S7C2@1236|Gammaproteobacteria,462GJ@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1531990_4	1123514.KB905899_gene1346	3.41e-112	327.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,460UF@72273|Thiotrichales	72273|Thiotrichales	K	PFAM Response regulator receiver domain	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_1079836_1	323850.Shew_1649	1.45e-113	335.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,2Q9HX@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_1024420_1	722419.PH505_am00500	3.37e-47	160.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,2PZVM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	NAD(P)H-binding	capD	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_1307108_1	411154.GFO_0295	6.12e-52	182.0	COG3203@1|root,COG3203@2|Bacteria,4PKBJ@976|Bacteroidetes,1HYG6@117743|Flavobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1136704_1	1123514.KB905899_gene2005	1.17e-36	135.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,460BC@72273|Thiotrichales	72273|Thiotrichales	Q	transporter, dctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1136704_2	90814.KL370891_gene57	1.98e-67	211.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,4611K@72273|Thiotrichales	72273|Thiotrichales	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_1532004_1	1123514.KB905899_gene469	1.65e-82	271.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QVX1@1224|Proteobacteria,1RP9I@1236|Gammaproteobacteria,460NE@72273|Thiotrichales	72273|Thiotrichales	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1024437_1	1172190.M947_10870	2.34e-92	292.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_685763_1	1178825.ALIH01000011_gene14	6.98e-49	169.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_1136719_1	521719.ATXQ01000006_gene1351	6.29e-61	199.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1YH9F@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	CF	Dihydroorotate dehydrogenase	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
k59_572316_1	1137281.D778_01682	9e-42	139.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1I450@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_572316_2	313598.MED152_07945	1.58e-151	435.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1HXBP@117743|Flavobacteriia,3VVRA@52959|Polaribacter	976|Bacteroidetes	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
k59_64101_1	572480.Arnit_2858	2.62e-102	298.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_1079874_1	666681.M301_0473	2.99e-78	261.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,2VKR2@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_120279_1	1163617.SCD_n00165	5.48e-94	288.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k59_1532026_1	153948.NAL212_2068	4.66e-21	87.4	2CEDU@1|root,333S9@2|Bacteria,1NCM4@1224|Proteobacteria,2WE3J@28216|Betaproteobacteria,374B8@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Domain of unknown function (DUF4156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4156
k59_1532026_2	1123518.ARWI01000001_gene254	7.06e-33	120.0	2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,461FP@72273|Thiotrichales	72273|Thiotrichales	S	Peptidoglycan-binding protein, CsiV	-	-	-	-	-	-	-	-	-	-	-	-	CsiV
k59_177303_1	1121931.AUHG01000016_gene1073	2.56e-124	362.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_459665_1	90814.KL370892_gene2316	3.69e-22	95.1	COG0715@1|root,COG0715@2|Bacteria,1NV0U@1224|Proteobacteria,1SNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
k59_1702093_1	572480.Arnit_1347	1.08e-194	558.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2YQUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_515444_1	1178825.ALIH01000003_gene2010	8.35e-148	421.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1HWUX@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_345833_1	391603.FBALC1_01922	7.3e-103	300.0	COG4638@1|root,COG4638@2|Bacteria,4NJ33@976|Bacteroidetes,1HZFM@117743|Flavobacteriia	976|Bacteroidetes	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k59_1532040_1	1458427.BAWN01000047_gene2115	6.46e-42	149.0	COG3597@1|root,COG3597@2|Bacteria,1QG9J@1224|Proteobacteria,2VIRR@28216|Betaproteobacteria,4AATU@80864|Comamonadaceae	28216|Betaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,TerB
k59_1532040_2	62928.azo2922	1.28e-09	53.9	2E5WI@1|root,330KJ@2|Bacteria,1N6RI@1224|Proteobacteria,2VXJ8@28216|Betaproteobacteria,2KXDW@206389|Rhodocyclales	206389|Rhodocyclales	S	Nif11 domain	-	-	-	-	-	-	-	-	-	-	-	-	Nif11
k59_798537_1	1178825.ALIH01000007_gene1752	2.87e-07	50.8	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1362300_2	1223410.KN050846_gene2044	8.77e-41	140.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1HY9J@117743|Flavobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_193716_3	1380600.AUYN01000006_gene632	5.5e-33	118.0	2E54M@1|root,32ZXJ@2|Bacteria,4NUYK@976|Bacteroidetes,1I501@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_645312_1	929558.SMGD1_0811	8.1e-71	214.0	COG2199@1|root,COG3706@2|Bacteria,1QUJM@1224|Proteobacteria,42TUI@68525|delta/epsilon subdivisions,2YPSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
k59_645312_2	929558.SMGD1_0810	7.28e-45	163.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_1040355_1	317025.Tcr_1439	2.54e-37	137.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,46053@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM ATPase, FliI YscN family	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1662129_1	391587.KAOT1_06702	1.05e-46	157.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1203376_1	1178825.ALIH01000006_gene1458	4.55e-118	351.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia	976|Bacteroidetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_532077_1	1406840.Q763_09750	2.3e-52	169.0	COG0497@1|root,COG0497@2|Bacteria,4NN6W@976|Bacteroidetes,1IJ34@117743|Flavobacteriia,2P0IJ@237|Flavobacterium	976|Bacteroidetes	L	DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_532077_2	1406840.Q763_09745	7.08e-142	402.0	COG0497@1|root,COG0497@2|Bacteria,4NPN4@976|Bacteroidetes,1I7GP@117743|Flavobacteriia,2NVZH@237|Flavobacterium	976|Bacteroidetes	L	DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_532077_3	1406840.Q763_09740	5.83e-18	79.7	COG0497@1|root,COG0497@2|Bacteria,4NMQC@976|Bacteroidetes,1IMS8@117743|Flavobacteriia,2NUD4@237|Flavobacterium	976|Bacteroidetes	L	Conjugal transfer protein TraI	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_645333_1	643867.Ftrac_3452	1.58e-98	304.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia	976|Bacteroidetes	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
k59_870811_1	1123514.KB905899_gene470	2.32e-161	491.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,4609U@72273|Thiotrichales	72273|Thiotrichales	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_1547672_1	1121931.AUHG01000011_gene1658	1.31e-192	549.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
k59_1492791_1	1123514.KB905899_gene1763	3.37e-33	138.0	COG0840@1|root,COG5001@1|root,COG0840@2|Bacteria,COG5001@2|Bacteria,1QX3B@1224|Proteobacteria,1T35M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_135893_1	90814.KL370891_gene1105	3.45e-92	273.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,461A2@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
k59_1662155_2	1565129.JSFF01000005_gene2286	4.3e-36	128.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1S8XT@1236|Gammaproteobacteria,2QA7C@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K18301	-	M00642	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	TetR_C_7,TetR_N
k59_1437060_1	1123518.ARWI01000001_gene2096	2e-40	145.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,45ZS1@72273|Thiotrichales	72273|Thiotrichales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1437060_2	1123518.ARWI01000001_gene2095	3.38e-56	184.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,4604R@72273|Thiotrichales	72273|Thiotrichales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_1549767_1	1353276.JADR01000009_gene1866	1.58e-54	186.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1549767_2	555500.I215_04735	8.67e-34	120.0	COG1595@1|root,COG1595@2|Bacteria,4NHNI@976|Bacteroidetes,1HY4K@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_928717_1	90371.CY43_11335	4.34e-30	118.0	COG2327@1|root,COG2327@2|Bacteria,1MXWP@1224|Proteobacteria,1RRDB@1236|Gammaproteobacteria,3ZM03@590|Salmonella	1236|Gammaproteobacteria	S	Polysaccharide pyruvyl transferase	wcaK	-	-	ko:K16710	-	-	-	-	ko00000	-	-	iECSF_1327.ECSF_1934,iSBO_1134.SBO_0872	PS_pyruv_trans
k59_928717_2	314275.MADE_1008195	6.53e-10	62.4	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,468KY@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	wcaL	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1494973_1	317025.Tcr_1204	5.13e-115	336.0	COG3435@1|root,COG3435@2|Bacteria,1RBES@1224|Proteobacteria,1S33X@1236|Gammaproteobacteria,460P2@72273|Thiotrichales	72273|Thiotrichales	Q	Gentisate 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1494973_2	90814.KL370891_gene1077	1.11e-78	240.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,462JT@72273|Thiotrichales	72273|Thiotrichales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1326304_1	572480.Arnit_2581	3.54e-173	490.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_82797_1	945713.IALB_2690	2.17e-88	280.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
k59_647434_1	1380600.AUYN01000001_gene2260	3.72e-92	293.0	COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_1097905_1	745718.JADT01000023_gene1447	2.54e-48	165.0	COG2234@1|root,COG2234@2|Bacteria,4NMZ4@976|Bacteroidetes,1HWZ9@117743|Flavobacteriia	976|Bacteroidetes	OU	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_1097905_2	1178825.ALIH01000001_gene2318	4.3e-43	156.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82807_1	411154.GFO_3101	8.37e-121	350.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1HWMH@117743|Flavobacteriia	976|Bacteroidetes	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_24639_1	1168067.JAGP01000001_gene1078	1.4e-53	181.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1SBFD@1236|Gammaproteobacteria,461AX@72273|Thiotrichales	72273|Thiotrichales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_24639_2	90814.KL370891_gene1487	4.38e-51	172.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,461U0@72273|Thiotrichales	72273|Thiotrichales	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
k59_138068_1	572480.Arnit_1662	1.96e-94	289.0	COG0745@1|root,COG0745@2|Bacteria,1R0ZN@1224|Proteobacteria,43D45@68525|delta/epsilon subdivisions	572480.Arnit_1662|-	KT	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1664274_1	411154.GFO_3466	8.56e-123	366.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_872958_1	391603.FBALC1_06653	1.15e-122	363.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
k59_82812_1	1380600.AUYN01000009_gene1045	2.32e-110	326.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HY65@117743|Flavobacteriia	976|Bacteroidetes	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_82812_2	1380600.AUYN01000009_gene1045	7.34e-168	478.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HY65@117743|Flavobacteriia	976|Bacteroidetes	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_252800_2	1123257.AUFV01000003_gene980	1.31e-15	75.9	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Alpha amylase catalytic	-	GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
k59_478373_2	1353276.JADR01000002_gene2107	1.33e-77	239.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1HX0W@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_421339_1	1178825.ALIH01000010_gene458	2.24e-115	343.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1HWP8@117743|Flavobacteriia	976|Bacteroidetes	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_421339_2	1178825.ALIH01000010_gene457	7.29e-156	442.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1HXBH@117743|Flavobacteriia	976|Bacteroidetes	I	Phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
k59_138077_1	1380600.AUYN01000009_gene1989	6.17e-171	486.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1154394_1	929558.SMGD1_1025	1.16e-70	228.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,43CEV@68525|delta/epsilon subdivisions,2YRH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1154395_1	1408224.SAMCCGM7_c2397	2e-21	92.4	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,4BA3D@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_1154395_2	1502724.FF80_00361	2.25e-38	135.0	COG3959@1|root,COG3959@2|Bacteria,1QZY7@1224|Proteobacteria,2TZMU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_872975_1	202954.BBNK01000016_gene3078	2.01e-18	84.3	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,3NKQF@468|Moraxellaceae	1236|Gammaproteobacteria	M	NeuB family	neuB	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k59_872975_2	1172190.M947_08505	7.1e-64	202.0	COG1011@1|root,COG1011@2|Bacteria,1RGM5@1224|Proteobacteria,42XRP@68525|delta/epsilon subdivisions,2YRWC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k59_363760_2	546274.EIKCOROL_01906	1.4e-14	72.4	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,2KPIX@206351|Neisseriales	206351|Neisseriales	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_1549843_1	572480.Arnit_1980	1.14e-104	312.0	2C76X@1|root,2ZM1W@2|Bacteria,1P5JD@1224|Proteobacteria,42P9T@68525|delta/epsilon subdivisions,2YMRC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1042551_1	318167.Sfri_0864	3.64e-06	47.8	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,2QC8A@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1042551_2	425104.Ssed_2309	1.4e-72	234.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RWWB@1236|Gammaproteobacteria,2QBDQ@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_705585_1	375451.RD1_0521	3.08e-27	115.0	COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,2TUCZ@28211|Alphaproteobacteria,2P2J9@2433|Roseobacter	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1
k59_590404_1	1168067.JAGP01000001_gene1731	1.24e-66	209.0	2AC0A@1|root,311I2@2|Bacteria,1RG7Y@1224|Proteobacteria,1S5RW@1236|Gammaproteobacteria,463D6@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k59_1777927_1	411154.GFO_1653	9.46e-37	137.0	COG0457@1|root,COG0457@2|Bacteria,4PKJM@976|Bacteroidetes,1IJB0@117743|Flavobacteriia	976|Bacteroidetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
k59_24684_1	880070.Cycma_0047	2.03e-32	125.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_24684_2	1122917.KB899672_gene824	1.17e-06	58.2	COG5002@1|root,COG5002@2|Bacteria,1UII2@1239|Firmicutes,4HGW5@91061|Bacilli,26QEY@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg,dCache_1
k59_1154428_1	563040.Saut_0479	5.05e-85	269.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,43AEI@68525|delta/epsilon subdivisions,2YT3E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_928807_1	1565129.JSFF01000014_gene413	6.84e-108	317.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,2QA4N@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Belongs to the arginase family	speB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11,3.5.3.8	ko:K01479,ko:K01480	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045,M00133	R01157,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02730,iECB_1328.ECB_02767,iECD_1391.ECD_02767,iSbBS512_1146.SbBS512_E3370	Arginase
k59_1777937_1	1453501.JELR01000002_gene579	8.1e-70	237.0	COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,464VX@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_196011_1	261292.Nit79A3_1938	3.77e-51	180.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2VI04@28216|Betaproteobacteria,37218@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_1097983_1	1005395.CSV86_08296	1.68e-63	209.0	29K7P@1|root,30752@2|Bacteria,1RDBV@1224|Proteobacteria,1SK7N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_759443_1	1137281.D778_02102	9.74e-72	226.0	COG4783@1|root,COG4783@2|Bacteria,4NM73@976|Bacteroidetes,1I1R8@117743|Flavobacteriia	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_19
k59_1664361_1	1469557.JSWF01000023_gene860	2.57e-120	367.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_196044_1	411154.GFO_1458	6.84e-34	122.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k59_196044_2	411154.GFO_1459	7.6e-61	191.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1HWJY@117743|Flavobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_1664370_1	411154.GFO_2174	4.48e-90	265.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_1326440_1	1121403.AUCV01000005_gene350	1.35e-67	214.0	2DP71@1|root,330U0@2|Bacteria,1R5A0@1224|Proteobacteria,42X0W@68525|delta/epsilon subdivisions,2WSIB@28221|Deltaproteobacteria,2MMBG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
k59_647564_1	1123514.KB905899_gene1265	3.99e-133	407.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PAS_9
k59_1098027_1	1046627.BZARG_1138	4.82e-83	262.0	COG0457@1|root,COG2819@1|root,COG0457@2|Bacteria,COG2819@2|Bacteria,4NN8M@976|Bacteroidetes,1I1EI@117743|Flavobacteriia	976|Bacteroidetes	NU	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_534362_1	1165841.SULAR_03857	1.34e-11	65.1	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_534362_2	889201.HMPREF9422_0848	9.84e-06	52.4	2CKMR@1|root,32VKF@2|Bacteria,1VAAV@1239|Firmicutes,4HKU6@91061|Bacilli	91061|Bacilli	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
k59_252914_1	572480.Arnit_1486	1.83e-79	268.0	COG2304@1|root,COG4254@1|root,COG2304@2|Bacteria,COG4254@2|Bacteria,1QU09@1224|Proteobacteria	1224|Proteobacteria	M	regulator of chromosome condensation, RCC1	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Cadherin,He_PIG,RHS_repeat
k59_1778016_1	944547.ABLL_2301	1.41e-97	296.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2YN2P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_1778016_2	367737.Abu_1827	2.79e-13	68.6	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_196075_1	765913.ThidrDRAFT_1968	2.34e-77	243.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1WWKM@135613|Chromatiales	135613|Chromatiales	E	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11069,ko:K11073	ko02010,map02010	M00299,M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1,3.A.1.11.2	-	-	SBP_bac_8
k59_196075_2	317025.Tcr_1906	4.2e-20	83.6	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,460IN@72273|Thiotrichales	72273|Thiotrichales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_817845_1	1123234.AUKI01000020_gene696	2.82e-105	318.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_252940_1	357804.Ping_1883	5.92e-78	254.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Pfam SNARE associated Golgi protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
k59_759511_1	709032.Sulku_2404	6.31e-91	276.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,42N2Z@68525|delta/epsilon subdivisions,2YN19@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	CDP-glucose 4,6-dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_981028_1	1392490.JHZX01000001_gene774	2.07e-92	293.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_817879_1	1121931.AUHG01000010_gene235	7.17e-97	298.0	COG3637@1|root,COG3637@2|Bacteria,4PKUA@976|Bacteroidetes,1IJF5@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1098093_1	886377.Murru_0375	6.47e-64	206.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWRZ@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_138244_1	411154.GFO_0488	1.1e-33	127.0	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes,1HXED@117743|Flavobacteriia	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_138244_2	411154.GFO_0487	8.47e-30	106.0	2EKEI@1|root,33E4Q@2|Bacteria,4NZ3B@976|Bacteroidetes,1I71D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
k59_138244_3	411154.GFO_0486	1.57e-17	77.0	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes,1I21F@117743|Flavobacteriia	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_252987_1	1178825.ALIH01000005_gene169	2.32e-58	194.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HYE9@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_252987_2	1380600.AUYN01000009_gene2000	4.5e-36	127.0	COG0513@1|root,COG0513@2|Bacteria,4NMA1@976|Bacteroidetes,1I2ZI@117743|Flavobacteriia	976|Bacteroidetes	JKL	RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD
k59_421522_1	572480.Arnit_0452	1.46e-119	348.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2YN2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_928945_1	90814.KL370891_gene1356	1.08e-170	482.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RY4X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	VVA0031	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_938773_3	1380600.AUYN01000009_gene1611	3.77e-12	62.8	COG2010@1|root,COG2010@2|Bacteria,4NVNJ@976|Bacteroidetes,1I68I@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_320249_3	1168067.JAGP01000001_gene403	1.9e-28	107.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM DJ-1 family protein	thiJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_1450891_1	929704.Myrod_3168	4.75e-12	66.2	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1HWYT@117743|Flavobacteriia,47IU5@76831|Myroides	976|Bacteroidetes	M	PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1450891_2	1249975.JQLP01000003_gene164	9.94e-49	167.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia,2P612@244698|Gillisia	976|Bacteroidetes	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1509551_1	1121035.AUCH01000004_gene342	3.91e-22	90.9	2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,2VUGJ@28216|Betaproteobacteria,2KZEY@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2846
k59_1509551_2	572480.Arnit_2775	5.74e-69	209.0	COG3564@1|root,COG3564@2|Bacteria,1RGYH@1224|Proteobacteria,42TFG@68525|delta/epsilon subdivisions,2YPF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF779)	-	-	-	ko:K09959	-	-	-	-	ko00000	-	-	-	DUF779
k59_96953_1	314285.KT71_09747	5.7e-31	125.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1J539@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	prsK	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c
k59_773127_1	1121898.Q766_00465	2.12e-15	81.3	COG1520@1|root,COG1520@2|Bacteria,4PPGQ@976|Bacteroidetes,1IKMC@117743|Flavobacteriia,2NUKU@237|Flavobacterium	976|Bacteroidetes	G	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
k59_1340849_1	1121918.ARWE01000001_gene3051	9.59e-36	131.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2WK9G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1340849_2	414684.RC1_2804	0.000427	41.6	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,2JQBK@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1563815_1	1123518.ARWI01000001_gene1096	1.51e-66	207.0	2EPRN@1|root,33HC6@2|Bacteria,1NI9T@1224|Proteobacteria,1SICJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1678276_1	929558.SMGD1_1526	1.42e-67	206.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2YP80@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_1678276_2	1172190.M947_05985	3.84e-92	270.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2YP70@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_1678276_3	1165841.SULAR_02623	1.96e-06	49.3	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2YPEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	ADP-ribose pyrophosphatase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_1282138_1	1172190.M947_04390	9.65e-113	337.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k59_1678280_1	43989.cce_0844	5.78e-12	62.8	COG3585@1|root,COG3585@2|Bacteria,1G9AG@1117|Cyanobacteria,3KIP8@43988|Cyanothece	1117|Cyanobacteria	H	TOBE domain	mop	-	-	-	-	-	-	-	-	-	-	-	TOBE
k59_1678280_2	543632.JOJL01000005_gene4706	7.67e-12	65.9	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DB53@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1509589_1	1355374.JARU01000002_gene1123	9.17e-44	153.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2YNA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cmeA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1509589_2	159450.NH14_28045	3.47e-14	72.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K0FI@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Efflux pump membrane transporter	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1340873_1	1380600.AUYN01000001_gene2495	1.59e-114	346.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_887047_1	589865.DaAHT2_0917	1.37e-15	78.6	28QK0@1|root,2ZD1U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k59_1563854_1	1380600.AUYN01000001_gene2677	1.41e-58	186.0	COG3279@1|root,COG3279@2|Bacteria,4NFN4@976|Bacteroidetes,1HYAZ@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_1563854_2	1380600.AUYN01000001_gene2678	8.5e-130	392.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1340900_1	1331060.RLDS_19090	4.6e-19	85.9	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,2K22T@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
k59_1340900_2	929558.SMGD1_0499	4.61e-88	265.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,42NYE@68525|delta/epsilon subdivisions,2YN2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_546619_1	926559.JoomaDRAFT_2322	1.53e-36	137.0	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_546619_2	1250232.JQNJ01000001_gene51	3.65e-57	183.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,1HXES@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1451005_1	1168067.JAGP01000001_gene1090	2.03e-71	230.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,4600C@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1451005_2	292415.Tbd_0620	1.02e-21	90.9	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,1KRZE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_1622608_1	1172190.M947_07290	6.84e-96	286.0	COG1876@1|root,COG1876@2|Bacteria,1RB64@1224|Proteobacteria,42R4D@68525|delta/epsilon subdivisions,2YNW7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
k59_1509646_1	319224.Sputcn32_3747	6.1e-100	291.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,2Q9YT@267890|Shewanellaceae	1236|Gammaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_492067_1	1121441.AUCX01000006_gene936	8.19e-38	151.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MHE4@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_3
k59_1168935_1	411154.GFO_2123	1.62e-56	181.0	COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1HY57@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k59_1168935_2	411154.GFO_2124	7.28e-38	137.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
k59_1451045_1	655815.ZPR_1079	8.75e-05	51.6	28IKH@1|root,2Z8M8@2|Bacteria,4NFVI@976|Bacteroidetes,1HWNR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1394602_1	1121912.AUHD01000006_gene1472	2.17e-107	334.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_1282246_1	1178825.ALIH01000001_gene2683	3.52e-40	135.0	2D57J@1|root,32TIE@2|Bacteria,4NSGD@976|Bacteroidetes,1I46S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1282246_2	1353276.JADR01000001_gene75	7.36e-93	288.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1HWX8@117743|Flavobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_1214471_1	1237149.C900_01123	2.5e-82	253.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,47KDM@768503|Cytophagia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1734706_1	616991.JPOO01000001_gene4383	3.03e-148	436.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia,23FM7@178469|Arenibacter	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1282256_1	1380600.AUYN01000006_gene288	4.22e-122	361.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_492114_1	90814.KL370891_gene1450	8.19e-76	229.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1S6RI@1236|Gammaproteobacteria,46341@72273|Thiotrichales	72273|Thiotrichales	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
k59_602820_1	1469613.JT55_04245	3.6e-13	68.2	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2TS3I@28211|Alphaproteobacteria,3FCPQ@34008|Rhodovulum	28211|Alphaproteobacteria	E	ABC transporter substrate-binding protein	MA20_23070	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_602820_2	1134474.O59_003410	3.25e-54	178.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1FGS9@10|Cellvibrio	1236|Gammaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_1340998_1	944547.ABLL_1646	3.02e-43	167.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
k59_1054803_1	90814.KL370891_gene1267	8.61e-98	286.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,460W4@72273|Thiotrichales	72273|Thiotrichales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_887181_1	1232410.KI421424_gene1677	8.13e-65	199.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,42W8Z@68525|delta/epsilon subdivisions,2WS5B@28221|Deltaproteobacteria,43V1B@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k59_1563984_1	945713.IALB_0604	1.17e-36	137.0	COG0433@1|root,COG1067@1|root,COG0433@2|Bacteria,COG1067@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770,ko:K06915	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_1563984_2	945713.IALB_0605	1.42e-07	53.1	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_210087_1	367737.Abu_0091	6.36e-39	134.0	2AJIW@1|root,31A5Q@2|Bacteria,1Q4ZS@1224|Proteobacteria,4308B@68525|delta/epsilon subdivisions,2YRXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
k59_210087_2	572480.Arnit_0293	1.64e-78	238.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_773318_1	1380600.AUYN01000006_gene581	1.2e-106	329.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1IJ7E@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1341026_1	1123326.JFBL01000001_gene1475	3.16e-08	54.3	COG1284@1|root,COG1284@2|Bacteria,1R3UZ@1224|Proteobacteria,42P9H@68525|delta/epsilon subdivisions,2YR79@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_1341026_2	572480.Arnit_1382	1.88e-40	141.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k59_1112230_1	765914.ThisiDRAFT_2337	9.64e-67	216.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales	135613|Chromatiales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1054819_1	446469.Sked_21050	5.99e-29	114.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1054819_2	326298.Suden_1450	1.06e-18	94.4	COG3206@1|root,COG3206@2|Bacteria,1Q26P@1224|Proteobacteria,42V2K@68525|delta/epsilon subdivisions,2YQ9I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1564004_1	411154.GFO_1915	6.42e-35	121.0	COG3296@1|root,COG3296@2|Bacteria,4NQGV@976|Bacteroidetes,1I2WN@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870,SHOCT
k59_1564004_2	1121931.AUHG01000001_gene3102	7.13e-85	259.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_832212_1	861208.AGROH133_04191	2.65e-11	65.5	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,4B9NN@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Glycolate oxidase subunit	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_832212_2	1123518.ARWI01000001_gene1392	5.16e-133	389.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,4603T@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_1678475_1	272942.RCAP_rcc01996	5.58e-41	154.0	COG1196@1|root,COG2911@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria,1R5PN@1224|Proteobacteria,2U1U2@28211|Alphaproteobacteria,1FCIV@1060|Rhodobacter	28211|Alphaproteobacteria	D	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_322971_1	504487.JCM19302_4145	6.83e-91	274.0	COG5309@1|root,COG5309@2|Bacteria,4NIVF@976|Bacteroidetes,1I014@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
k59_1214541_1	326298.Suden_0132	4.03e-80	239.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2YP3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_1214541_2	1123517.JOMR01000001_gene280	9.28e-08	54.7	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_662018_1	59538.XP_005974309.1	5.02e-26	106.0	COG0489@1|root,KOG3022@2759|Eukaryota,38I4K@33154|Opisthokonta,3BAU1@33208|Metazoa,3CVS5@33213|Bilateria,481M0@7711|Chordata,4957J@7742|Vertebrata,3J9H4@40674|Mammalia	33208|Metazoa	D	mitochondrion morphogenesis	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_662018_2	75379.Tint_0988	1.8e-53	184.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,1KJH1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_662028_1	1094466.KQS_04285	6.99e-51	171.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1HXKY@117743|Flavobacteriia,2NTG5@237|Flavobacterium	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_662028_2	1296415.JACC01000025_gene1683	1.11e-34	123.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1I181@117743|Flavobacteriia,2YHFK@290174|Aquimarina	976|Bacteroidetes	O	GrpE	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_1341085_1	391587.KAOT1_12822	1.26e-154	442.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1HXJC@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1169101_1	985255.APHJ01000024_gene1208	1.46e-11	63.9	COG2982@1|root,COG2982@2|Bacteria,4NIE2@976|Bacteroidetes,1HZC9@117743|Flavobacteriia,2P7C0@244698|Gillisia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1169101_2	411154.GFO_0621	1.94e-40	138.0	28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,1I3WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_435709_1	323850.Shew_1629	4.77e-70	221.0	2DN8R@1|root,32UIH@2|Bacteria,1N2YF@1224|Proteobacteria,1SA45@1236|Gammaproteobacteria,2Q90A@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Peptidoglycan-binding protein, CsiV	-	-	-	-	-	-	-	-	-	-	-	-	CsiV
k59_1564080_1	411154.GFO_3534	1.06e-72	232.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_1564080_2	411154.GFO_3535	8.58e-85	276.0	COG1361@1|root,COG1361@2|Bacteria,4PM78@976|Bacteroidetes,1IJZ7@117743|Flavobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
k59_210178_1	411154.GFO_3215	9.51e-91	271.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_1792100_1	1123514.KB905899_gene1491	1.56e-65	206.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,4609A@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_1792100_2	314254.OA2633_01239	4.91e-08	53.5	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,43XHY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_1054896_1	563040.Saut_0341	1.4e-164	471.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2YM91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1734849_1	504487.JCM19302_558	1.6e-75	229.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1HXCT@117743|Flavobacteriia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
k59_1734849_2	1178825.ALIH01000007_gene1716	2.23e-108	322.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1HXQX@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_720804_1	1484460.JSWG01000006_gene2739	4.22e-190	565.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_720804_2	1121875.KB907546_gene2494	3.59e-96	293.0	COG3250@1|root,COG3250@2|Bacteria,4NHRV@976|Bacteroidetes,1IKPT@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_1394762_2	1380600.AUYN01000006_gene484	3.17e-31	124.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HXVC@117743|Flavobacteriia	976|Bacteroidetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
k59_266211_2	177437.HRM2_39760	7.45e-111	327.0	COG0551@1|root,COG0551@2|Bacteria,1PZFI@1224|Proteobacteria,42PNP@68525|delta/epsilon subdivisions,2WN2Q@28221|Deltaproteobacteria,2MK31@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
k59_720809_1	1380600.AUYN01000007_gene3074	8.5e-119	348.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_377766_1	572480.Arnit_1313	7.59e-98	295.0	COG3347@1|root,COG3347@2|Bacteria,1QVWU@1224|Proteobacteria,43CKY@68525|delta/epsilon subdivisions,2YNA2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
k59_832306_1	318161.Sden_1045	7.05e-140	408.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,2Q9R5@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_1341162_1	323850.Shew_2972	3.65e-102	305.0	COG2357@1|root,COG2357@2|Bacteria,1MYTM@1224|Proteobacteria,1S795@1236|Gammaproteobacteria,2Q9X1@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_887329_1	387092.NIS_1128	3.84e-16	83.6	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_227987_1	504487.JCM19302_3848	1.14e-08	55.1	28J46@1|root,2Z906@2|Bacteria,4NFYM@976|Bacteroidetes,1HX14@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
k59_227987_2	1347342.BN863_32930	6.16e-253	698.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1HXBZ@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_227987_3	1121007.AUML01000061_gene627	4.4e-05	45.4	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HXFT@117743|Flavobacteriia,2YHHR@290174|Aquimarina	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_679928_2	386793.Q0E5Y0_9CAUD	2.15e-91	282.0	4QARC@10239|Viruses,4QV4E@35237|dsDNA viruses  no RNA stage,4QPDS@28883|Caudovirales,4QP0H@10744|Podoviridae	10744|Podoviridae	S	nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_962219_1	572480.Arnit_0091	7.54e-168	474.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2YN4W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_1753129_1	1353528.DT23_02440	1.2e-113	335.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TU94@28211|Alphaproteobacteria,2XMI4@285107|Thioclava	28211|Alphaproteobacteria	I	3-oxoacyl-ACP synthase	fabH_2	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1188273_1	1450525.JATV01000014_gene2253	2.06e-47	165.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1HWRV@117743|Flavobacteriia,2NTGI@237|Flavobacterium	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1018846_1	572480.Arnit_2776	7.94e-114	339.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	aldB	-	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_1188276_1	1123518.ARWI01000001_gene1989	3.68e-90	278.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,461DX@72273|Thiotrichales	72273|Thiotrichales	I	aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_228014_2	504487.JCM19302_345	1.23e-80	244.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_228016_1	563040.Saut_0700	4.45e-05	44.7	COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,42M9H@68525|delta/epsilon subdivisions,2YMZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_228016_2	929558.SMGD1_2177	7.65e-33	115.0	COG2740@1|root,COG2740@2|Bacteria,1Q3GD@1224|Proteobacteria,42XA3@68525|delta/epsilon subdivisions,2YQQ2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	-	-	-	-	-	-	-	-	-	DUF448
k59_228016_3	326298.Suden_0676	1.09e-85	281.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1301381_1	1355374.JARU01000001_gene637	6.57e-70	230.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,42PDP@68525|delta/epsilon subdivisions,2YMI8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	two-component sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA_2
k59_1244213_1	1380600.AUYN01000007_gene3396	5.65e-25	97.4	2AT2U@1|root,31IIU@2|Bacteria,4NS9K@976|Bacteroidetes,1I3WD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1244213_2	1178825.ALIH01000003_gene2023	3.56e-147	418.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1244213_3	1469557.JSWF01000031_gene1955	4.33e-88	268.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia	976|Bacteroidetes	EJ	GlutRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_1527097_1	1049564.TevJSym_bk00070	1.13e-35	125.0	COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,1T3Z1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
k59_58641_1	1041826.FCOL_09575	4.6e-32	130.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,4NJ3U@976|Bacteroidetes,1HZWJ@117743|Flavobacteriia,2NXRP@237|Flavobacterium	976|Bacteroidetes	L	Pfam:Methyltransf_26	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
k59_1018893_2	90814.KL370891_gene1318	4.39e-38	135.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,460ZA@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1131877_1	55207.KP22_10245	2.1e-62	206.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1640343_1	1120949.KB903313_gene419	4.89e-23	95.5	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4DC76@85008|Micromonosporales	201174|Actinobacteria	NOU	Bacterial Peptidase A24 N-terminal domain	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_1753185_1	1380600.AUYN01000007_gene3353	0.0	1026.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_680003_1	1250232.JQNJ01000001_gene2716	5.03e-11	63.2	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1HZCR@117743|Flavobacteriia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_680003_2	1124780.ANNU01000077_gene789	4.38e-130	390.0	COG0477@1|root,COG0477@2|Bacteria,4PKTJ@976|Bacteroidetes,47YD9@768503|Cytophagia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1.3	-	-	Sugar_tr
k59_680003_3	143224.JQMD01000002_gene3707	3.37e-68	218.0	COG3970@1|root,COG3970@2|Bacteria,4NGTH@976|Bacteroidetes,1I0WA@117743|Flavobacteriia	976|Bacteroidetes	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
k59_1357387_1	411154.GFO_1627	2.58e-120	351.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_1357387_2	946077.W5A_11671	1.48e-76	235.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1HY0C@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_962287_1	935557.ATYB01000008_gene5989	1.92e-12	67.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,4BDTZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_962287_2	317025.Tcr_1185	8.61e-23	97.4	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_962287_3	317025.Tcr_1184	2.27e-209	590.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,45ZVZ@72273|Thiotrichales	72273|Thiotrichales	P	inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_1188341_2	1123514.KB905899_gene2009	1.97e-78	237.0	COG3193@1|root,COG3193@2|Bacteria,1REZG@1224|Proteobacteria,1S5K5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_454076_1	90814.KL370891_gene291	1.41e-131	382.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4607B@72273|Thiotrichales	72273|Thiotrichales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_454076_2	717772.THIAE_01025	2.16e-50	170.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,45ZZ1@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_962288_1	1137281.D778_01517	5.07e-12	65.9	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_962288_2	1380600.AUYN01000001_gene2540	2.12e-40	137.0	2CJVT@1|root,32W50@2|Bacteria,4NTGQ@976|Bacteroidetes,1I509@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_962288_3	1380600.AUYN01000001_gene2539	5.66e-127	367.0	2DBE6@1|root,2Z8R0@2|Bacteria,4NGQS@976|Bacteroidetes,1HZNC@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k59_962288_4	1380600.AUYN01000001_gene2538	8.27e-65	205.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1696669_1	1122985.HMPREF1991_01298	5.92e-20	92.8	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1640360_1	1123518.ARWI01000001_gene913	2.25e-72	219.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,460YN@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
k59_1640360_2	317025.Tcr_0402	7.48e-163	457.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,45ZTM@72273|Thiotrichales	72273|Thiotrichales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_1640360_3	1123514.KB905899_gene1701	1.15e-56	184.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,4615X@72273|Thiotrichales	72273|Thiotrichales	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
k59_340676_1	1122621.ATZA01000010_gene184	6.89e-06	50.8	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1IPTX@117747|Sphingobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_340676_2	411154.GFO_1943	2.9e-38	142.0	COG0178@1|root,COG0178@2|Bacteria,4NGEE@976|Bacteroidetes,1I0HF@117743|Flavobacteriia	976|Bacteroidetes	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_115177_1	411154.GFO_3462	1.09e-58	201.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Y_Y_Y
k59_171660_1	1123517.JOMR01000001_gene1389	4.65e-172	501.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria,1T298@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_736483_1	945713.IALB_0960	1.68e-73	244.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_1131945_1	1392490.JHZX01000001_gene2883	8e-54	179.0	2ARUG@1|root,31H61@2|Bacteria,4NRDB@976|Bacteroidetes,1I73R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1583742_1	1123514.KB905899_gene442	2.01e-114	343.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RMXA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fad linked oxidase	dprE1	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
k59_1583742_2	720554.Clocl_1188	2.33e-07	50.8	COG2246@1|root,COG2246@2|Bacteria,1VWK2@1239|Firmicutes,250SF@186801|Clostridia,3WPB0@541000|Ruminococcaceae	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k59_115197_1	90814.KL370891_gene626	1.91e-204	592.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_397599_1	929558.SMGD1_1897	1.95e-79	254.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42MS0@68525|delta/epsilon subdivisions,2YMTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_3
k59_397599_2	326298.Suden_0520	8.68e-120	367.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1527186_1	1380600.AUYN01000009_gene1127	1.07e-114	342.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1470252_1	929558.SMGD1_2417	1.21e-106	320.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2YNK3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_1696724_1	1131812.JQMS01000001_gene2130	2.01e-110	329.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia,2NV0D@237|Flavobacterium	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_680073_1	411154.GFO_0118	4.29e-116	335.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_58740_1	930169.B5T_00164	5.94e-95	291.0	COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,1S1R2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methylamine dehydrogenase heavy chain (MADH)	-	-	1.4.9.1	ko:K15229	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_H
k59_58740_2	1123517.JOMR01000001_gene522	2.84e-43	145.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,45ZW8@72273|Thiotrichales	72273|Thiotrichales	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_58740_3	1168067.JAGP01000001_gene201	1.39e-55	177.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,45ZW8@72273|Thiotrichales	72273|Thiotrichales	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_58740_4	1168067.JAGP01000001_gene1184	1.68e-58	183.0	COG0607@1|root,COG0607@2|Bacteria,1PH28@1224|Proteobacteria,1SWJ9@1236|Gammaproteobacteria,461CK@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1188430_1	945713.IALB_2191	5.11e-60	198.0	COG0044@1|root,COG0044@2|Bacteria	2|Bacteria	F	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_171724_1	1123514.KB905899_gene1712	3.74e-162	466.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,460DY@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1640451_1	945713.IALB_0774	1.01e-82	258.0	COG0541@1|root,COG0541@2|Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1301545_1	643867.Ftrac_1808	3.47e-35	142.0	COG0515@1|root,COG2203@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,4PM99@976|Bacteroidetes,47KKS@768503|Cytophagia	976|Bacteroidetes	KLT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,Pkinase,SpoIIE
k59_1583810_1	203908.EGG10111	3.28e-12	70.5	COG0642@1|root,COG5641@1|root,KOG0519@2759|Eukaryota,KOG1601@2759|Eukaryota,39S94@33154|Opisthokonta,3NVPC@4751|Fungi,3UZJ7@5204|Basidiomycota,2YC7Z@29000|Pucciniomycotina	4751|Fungi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_1303073_1	1123367.C666_04180	2.83e-27	109.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KUC6@206389|Rhodocyclales	206389|Rhodocyclales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1303073_2	76114.ebA3981	6.57e-154	435.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1358652_1	1380600.AUYN01000001_gene2494	2.47e-96	285.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1HYEY@117743|Flavobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1528504_1	1172190.M947_01190	3.52e-91	286.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42WJ0@68525|delta/epsilon subdivisions,2YQJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_229681_1	1380600.AUYN01000007_gene3188	7.42e-204	567.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_229681_2	1392488.JHZY01000002_gene1586	1.16e-15	76.3	2BUVU@1|root,32Q7V@2|Bacteria,4P9WJ@976|Bacteroidetes,1IEK3@117743|Flavobacteriia,2XKE8@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_229681_3	1380600.AUYN01000007_gene3174	6.42e-07	50.4	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1641943_1	643867.Ftrac_1731	1.01e-87	282.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_60182_1	688270.Celal_1989	3.06e-12	69.7	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HXVC@117743|Flavobacteriia,1F8PD@104264|Cellulophaga	976|Bacteroidetes	KMT	TIGRFAM TonB family C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
k59_60182_2	760192.Halhy_5192	0.00024	43.1	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1ITI1@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
k59_1585345_1	983544.Lacal_1620	4.59e-94	280.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_850217_1	504487.JCM19302_248	1.27e-84	264.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1245671_2	1123514.KB905901_gene153	3.16e-153	436.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
k59_1358659_1	367737.Abu_0940	3.29e-70	253.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,42MHY@68525|delta/epsilon subdivisions,2YNDP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	domain protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg_2,Haemagg_act
k59_963726_1	984262.SGRA_3848	3.11e-65	212.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1IP0G@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_1189345_1	1121931.AUHG01000016_gene1043	6.07e-51	169.0	COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,1HYAC@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
k59_1189345_2	1121931.AUHG01000016_gene1044	4.2e-63	205.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_1088366_1	1121921.KB898714_gene1876	2.45e-10	66.6	COG3291@1|root,COG3291@2|Bacteria,1R2F8@1224|Proteobacteria,1T5PN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cellulose binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_3,Glyco_hydro_9
k59_186307_1	572480.Arnit_2478	8.57e-151	432.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2YMU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_863334_1	313598.MED152_11869	1.93e-47	160.0	COG2049@1|root,COG2049@2|Bacteria,4NMNT@976|Bacteroidetes,1I1C1@117743|Flavobacteriia,3VV93@52959|Polaribacter	976|Bacteroidetes	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
k59_863334_2	354242.CJJ81176_1526	1.04e-21	92.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,42QNE@68525|delta/epsilon subdivisions,2YNCP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k59_1316319_2	44251.PDUR_24845	3.56e-22	94.4	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,26RIV@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	spsJ	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_354454_1	563040.Saut_2123	6.53e-194	543.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2YMD9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_354454_2	929558.SMGD1_1202	6.76e-11	61.6	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2YMC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0566	DAP_epimerase
k59_411714_1	1122599.AUGR01000003_gene2017	1.78e-102	312.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,1RPX7@1236|Gammaproteobacteria,1XHHI@135619|Oceanospirillales	135619|Oceanospirillales	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
k59_1767836_1	411154.GFO_3395	8.43e-90	277.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1HWRE@117743|Flavobacteriia	976|Bacteroidetes	MU	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1767836_2	411154.GFO_3395	4.49e-107	321.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1HWRE@117743|Flavobacteriia	976|Bacteroidetes	MU	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1711146_1	90814.KL370892_gene2310	1.6e-147	421.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,460C4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11
k59_15391_1	1565129.JSFF01000017_gene2946	4.77e-52	176.0	2CG2X@1|root,2Z7NT@2|Bacteria,1MW33@1224|Proteobacteria,1RQZI@1236|Gammaproteobacteria,2Q90Y@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	VP1614	-	-	-	-	-	-	-	-	-	-	-	-
k59_15391_2	323850.Shew_0761	1.44e-43	146.0	2FE19@1|root,3461G@2|Bacteria,1P06T@1224|Proteobacteria,1SS76@1236|Gammaproteobacteria,2QBTJ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1598585_1	1121931.AUHG01000012_gene2850	2.51e-67	207.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1598585_2	411154.GFO_1053	9.6e-67	212.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1HWUF@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
k59_637988_1	1232410.KI421424_gene1685	6.46e-156	454.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,43RZZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_1654696_1	572480.Arnit_1481	5.96e-101	321.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_15409_2	1046627.BZARG_3121	1.78e-35	130.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HXDJ@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_1711171_1	1123326.JFBL01000006_gene948	5.66e-125	367.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2YMYK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
k59_863415_1	1121931.AUHG01000011_gene2121	8.2e-104	311.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1HXUW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_638025_2	421052.F945_02277	1.68e-06	51.2	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1SDNA@1236|Gammaproteobacteria,3NJ5R@468|Moraxellaceae	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K18301	-	M00642	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	TetR_C_7,TetR_N
k59_298851_1	1123518.ARWI01000001_gene286	2.2e-232	657.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales	72273|Thiotrichales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_807489_1	504487.JCM19302_3916	1.61e-76	231.0	COG3577@1|root,COG3577@2|Bacteria,4NNI0@976|Bacteroidetes,1I1Z6@117743|Flavobacteriia	976|Bacteroidetes	S	protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
k59_807489_2	1380600.AUYN01000007_gene3391	1.72e-96	286.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes,1I0A6@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_524511_1	945713.IALB_2986	9.58e-46	152.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cytM	-	-	ko:K00405,ko:K03888,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.3,3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1485177_1	1137281.D778_00333	1.42e-212	591.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1HYBQ@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1485177_2	504487.JCM19302_1767	5.58e-61	192.0	COG0526@1|root,COG0526@2|Bacteria,4NR1X@976|Bacteroidetes,1I2WZ@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase	tlpA	-	-	-	-	-	-	-	-	-	-	-	Redoxin,Thioredoxin_8
k59_1485177_3	1197477.IA57_09405	1.29e-09	57.8	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_15452_1	1123228.AUIH01000022_gene3111	7.42e-82	254.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XI7F@135619|Oceanospirillales	135619|Oceanospirillales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_15452_2	861208.AGROH133_02857	5.69e-06	46.6	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,4B89D@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_15462_1	1203550.HMPREF1475_01429	3.97e-22	95.1	COG0545@1|root,COG0545@2|Bacteria,4NJKK@976|Bacteroidetes,2G320@200643|Bacteroidia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_1258568_1	1178825.ALIH01000004_gene2947	3.17e-87	263.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1258568_2	1484460.JSWG01000015_gene988	7.01e-30	110.0	COG2010@1|root,COG2010@2|Bacteria,4NS6Z@976|Bacteroidetes,1I42Z@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_242865_1	572480.Arnit_3007	8.63e-149	427.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2YM9G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1428035_1	411154.GFO_1878	3.57e-69	224.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1428035_2	411154.GFO_1879	1.84e-25	102.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1HXF8@117743|Flavobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_1428046_1	1168067.JAGP01000001_gene694	4.16e-116	366.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_1428046_2	1123518.ARWI01000001_gene2155	1.95e-32	124.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_1370973_1	1565129.JSFF01000022_gene1421	3.54e-114	353.0	COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,2Q8VC@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Belongs to the peptidase M16 family	ptrA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M
k59_1145086_1	387093.SUN_1534	1.24e-34	133.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2YN3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Alginate O-acetylation protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_1767966_1	90814.KL370892_gene2222	6.42e-108	317.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,4610S@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1767966_2	90814.KL370892_gene2223	1.55e-30	117.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,45ZN6@72273|Thiotrichales	72273|Thiotrichales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_186460_1	326298.Suden_1236	8.62e-54	178.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,42RBG@68525|delta/epsilon subdivisions,2YP5T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_186460_2	1123518.ARWI01000001_gene1758	1.68e-18	80.1	2EQTE@1|root,33ID4@2|Bacteria,1RKB7@1224|Proteobacteria,1S6DN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_468770_1	94122.Shewana3_0923	3.77e-05	52.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QBFX@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_1711261_1	411154.GFO_1633	4.5e-137	396.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1088523_1	572480.Arnit_0923	8.37e-70	216.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2YMSS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_1088523_2	572480.Arnit_0922	5.01e-194	541.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2YM8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_750218_3	1123514.KB905899_gene1775	2.76e-49	169.0	COG2223@1|root,COG2223@2|Bacteria,1QVX0@1224|Proteobacteria,1T2MB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1540652_1	572480.Arnit_0819	8.15e-111	321.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,42QWJ@68525|delta/epsilon subdivisions,2YNVX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k59_1540652_2	572480.Arnit_0818	9e-58	197.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,43019@68525|delta/epsilon subdivisions,2YRSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_638115_1	1469557.JSWF01000032_gene3125	1.52e-55	187.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1HXK1@117743|Flavobacteriia	976|Bacteroidetes	S	FAD-dependent	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
k59_638115_2	1392488.JHZY01000002_gene467	1.15e-199	577.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia,2XI9W@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1258627_1	1168067.JAGP01000001_gene105	4.35e-68	221.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,460ZZ@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_1258627_2	1286106.MPL1_09325	9.39e-121	351.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,4606Z@72273|Thiotrichales	72273|Thiotrichales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_1258627_3	317025.Tcr_1601	1.62e-05	46.2	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,45ZWE@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_581388_1	1249480.B649_05365	3e-108	341.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_1768000_1	317025.Tcr_1437	1.11e-11	66.6	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,461BA@72273|Thiotrichales	72273|Thiotrichales	N	Flagellar hook-length control protein	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
k59_1768000_2	1123514.KB905899_gene1431	6.45e-27	109.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462BB@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1712919_1	563040.Saut_2017	1.59e-32	118.0	COG0775@1|root,COG0775@2|Bacteria,1QSEF@1224|Proteobacteria,42X56@68525|delta/epsilon subdivisions,2YQPV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_1090077_1	62928.azo1278	6.18e-59	206.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVC7@206389|Rhodocyclales	206389|Rhodocyclales	T	PAC sensor-containing diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS,PAS_9
k59_809249_2	929558.SMGD1_1061	6.87e-42	140.0	COG2078@1|root,COG2078@2|Bacteria,1Q5PY@1224|Proteobacteria,431KR@68525|delta/epsilon subdivisions,2YSE9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_639739_2	1380600.AUYN01000001_gene2188	2.71e-33	123.0	2EBG7@1|root,335GS@2|Bacteria,4NWSB@976|Bacteroidetes,1I5CC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_696930_1	1442598.JABW01000002_gene1752	5.07e-28	117.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1MXA3@1224|Proteobacteria,43AUG@68525|delta/epsilon subdivisions,2YN4Q@29547|Epsilonproteobacteria	1224|Proteobacteria	T	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	GGDEF,HATPase_c,HisKA,NMT1,SBP_bac_3
k59_1769648_1	563040.Saut_2093	2.88e-71	219.0	COG4244@1|root,COG4244@2|Bacteria,1PJNV@1224|Proteobacteria,42TI9@68525|delta/epsilon subdivisions,2YQ43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_975154_1	497321.C664_03565	6.64e-152	437.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,2KVIV@206389|Rhodocyclales	206389|Rhodocyclales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1199249_1	616991.JPOO01000001_gene2953	3.7e-26	112.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,23G3Y@178469|Arenibacter	976|Bacteroidetes	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
k59_75161_1	1178825.ALIH01000008_gene717	4.13e-71	223.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1542188_1	523850.TON_1291	1.08e-12	67.8	COG2095@1|root,arCOG01997@2157|Archaea,2XZEI@28890|Euryarchaeota,243TP@183968|Thermococci	183968|Thermococci	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_300660_1	745718.JADT01000001_gene2050	3.04e-61	202.0	COG3344@1|root,COG3344@2|Bacteria,4NJS7@976|Bacteroidetes,1HYXK@117743|Flavobacteriia	976|Bacteroidetes	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_300660_2	1380600.AUYN01000009_gene1619	4.66e-16	77.8	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1712966_1	411154.GFO_0341	3.06e-152	436.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1HXQX@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_921196_1	1392490.JHZX01000001_gene349	0.0	1239.0	COG0642@1|root,COG0745@1|root,COG1879@1|root,COG0745@2|Bacteria,COG1879@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Peripla_BP_4,Response_reg
k59_1429674_1	1121931.AUHG01000010_gene870	5.73e-110	320.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_244632_1	1178825.ALIH01000007_gene1676	4.33e-66	204.0	COG1246@1|root,COG1246@2|Bacteria,4NGXY@976|Bacteroidetes,1HZSQ@117743|Flavobacteriia	976|Bacteroidetes	E	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_244632_2	1380600.AUYN01000009_gene1046	2.52e-83	250.0	COG3241@1|root,COG3241@2|Bacteria,4NQ6P@976|Bacteroidetes,1I34Z@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM Copper binding proteins, plastocyanin azurin family	azu	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
k59_244632_3	1380600.AUYN01000009_gene1166	1.76e-17	80.9	COG1012@1|root,COG1012@2|Bacteria,4NEQ2@976|Bacteroidetes,1HYQ7@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	gapN	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_809303_2	572480.Arnit_1395	1.27e-64	200.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	mshO	-	-	ko:K02456,ko:K02679,ko:K12285	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_751807_2	335541.Swol_1040	5.35e-37	143.0	COG1145@1|root,COG4191@1|root,COG4624@1|root,COG1145@2|Bacteria,COG4191@2|Bacteria,COG4624@2|Bacteria,1TSVR@1239|Firmicutes,248TC@186801|Clostridia	186801|Clostridia	CNT	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,MCPsignal
k59_300677_1	1380600.AUYN01000009_gene1307	6.02e-143	431.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_639801_1	1123518.ARWI01000001_gene316	3.93e-50	175.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent Clp protease ATP-binding subunit ClpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_639801_2	90814.KL370891_gene978	2.98e-59	184.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,46127@72273|Thiotrichales	72273|Thiotrichales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k59_366652_3	1476902.A0A067ZI79_9CAUD	4.53e-07	50.8	4QB9S@10239|Viruses,4QUXK@35237|dsDNA viruses  no RNA stage,4QPW1@28883|Caudovirales,4QIMD@10662|Myoviridae	10662|Myoviridae	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_931531_1	1168067.JAGP01000001_gene1183	9.82e-178	508.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,45ZQM@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_593150_1	572480.Arnit_0142	1.85e-84	267.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1045292_2	1249480.B649_06820	1.77e-74	233.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2YNBV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3864 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k59_27410_1	1217703.F904_00437	4.67e-44	156.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,3NJ3Z@468|Moraxellaceae	1236|Gammaproteobacteria	J	tRNA synthetases class II (D, K and N)	epmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k59_1723547_1	638301.HMPREF0444_0237	5.93e-39	140.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,27FYM@186828|Carnobacteriaceae	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_1045294_1	649349.Lbys_2632	3.26e-10	60.1	COG1216@1|root,COG1216@2|Bacteria,4NJWR@976|Bacteroidetes,47P3Y@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1045294_2	1178825.ALIH01000005_gene312	4.89e-90	275.0	COG1215@1|root,COG1215@2|Bacteria,4NU2D@976|Bacteroidetes,1I8D0@117743|Flavobacteriia	976|Bacteroidetes	M	Capsular biosynthesis protein CpsI	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1329291_1	1123261.AXDW01000003_gene1911	0.000117	43.1	COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,1SBCW@1236|Gammaproteobacteria,1X71P@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
k59_1329291_2	399739.Pmen_4223	1.18e-94	282.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_481302_1	1123514.KB905899_gene1955	5.55e-175	514.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_481302_2	1123514.KB905899_gene1954	1.75e-24	94.4	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1RTX4@1236|Gammaproteobacteria,461HH@72273|Thiotrichales	72273|Thiotrichales	P	cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_1157390_1	90814.KL370891_gene1257	1.42e-207	613.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1667088_1	1278307.KB907029_gene463	2.24e-125	382.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na Pi-Cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_85757_1	929558.SMGD1_1315	1.53e-60	194.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2YNJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_85757_2	929558.SMGD1_1314	1.59e-19	87.4	COG3137@1|root,COG3137@2|Bacteria,1PWI2@1224|Proteobacteria,42W3Z@68525|delta/epsilon subdivisions,2YQX2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
k59_983799_1	338963.Pcar_2172	5.53e-19	87.4	2AD3M@1|root,312RX@2|Bacteria,1RGF2@1224|Proteobacteria,42RXJ@68525|delta/epsilon subdivisions,2WNM9@28221|Deltaproteobacteria,43SIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_255896_1	929558.SMGD1_1178	1.16e-39	135.0	2AJSH@1|root,31AEU@2|Bacteria,1Q5GG@1224|Proteobacteria,42QZH@68525|delta/epsilon subdivisions,2YP33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_255896_2	929558.SMGD1_1177	1.95e-40	142.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_1723584_1	563040.Saut_0272	3.68e-65	213.0	COG3156@1|root,COG3156@2|Bacteria	2|Bacteria	U	protein secretion	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cna_B,Collagen_bind,FctA,Gram_pos_anchor,SdrD_B,T2SSK
k59_1667123_1	411154.GFO_2287	6.59e-188	526.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1HYBW@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleoid-associated protein NdpA	-	-	-	-	-	-	-	-	-	-	-	-	NA37
k59_85790_1	709032.Sulku_1837	2.62e-25	98.2	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2YNZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_1271044_1	1121875.KB907550_gene805	1.78e-55	177.0	COG1959@1|root,COG1959@2|Bacteria,4NPHI@976|Bacteroidetes,1I2QC@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1271044_2	1197477.IA57_03465	0.000271	43.9	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1I1GF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1723606_1	411154.GFO_1531	3.05e-139	398.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1HWYR@117743|Flavobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_931609_1	572480.Arnit_1872	1.35e-09	56.6	2FG8G@1|root,3484V@2|Bacteria,1P3EM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_931609_2	572480.Arnit_1870	2.69e-91	276.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_650434_1	1250005.PHEL85_1542	5.58e-34	118.0	2E43V@1|root,32Z06@2|Bacteria,4NUX4@976|Bacteroidetes,1I5MX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_481353_1	411154.GFO_3015	1.14e-193	544.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_481353_2	411154.GFO_3014	1.47e-33	120.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
k59_27481_1	28229.ND2E_2859	3.4e-30	120.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1Q94S@1224|Proteobacteria,1RNU5@1236|Gammaproteobacteria,2Q7UZ@267889|Colwelliaceae	1236|Gammaproteobacteria	KLT	Leucine rich repeat	VP1985	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,Pkinase,Pkinase_Tyr
k59_1383086_1	1469607.KK073768_gene723	1.28e-15	75.9	COG5635@1|root,COG5635@2|Bacteria,1GDR0@1117|Cyanobacteria	1117|Cyanobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_311450_1	1123228.AUIH01000007_gene2567	2e-84	263.0	28KNR@1|root,2Z9F7@2|Bacteria,1NC4P@1224|Proteobacteria,1RS28@1236|Gammaproteobacteria,1XP7V@135619|Oceanospirillales	135619|Oceanospirillales	S	Glycosyl hydrolase family 79, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_79n
k59_1780947_1	1137281.D778_00805	4.11e-180	519.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_762337_1	1380600.AUYN01000009_gene2145	1.19e-80	258.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1HWQ0@117743|Flavobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_762337_2	1178825.ALIH01000006_gene1492	1.52e-168	476.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia	976|Bacteroidetes	S	related to 2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_1552755_1	745718.JADT01000008_gene3135	1.12e-70	216.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1HX1E@117743|Flavobacteriia	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_1552755_2	641526.ADIWIN_1827	5.88e-54	169.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1I2TX@117743|Flavobacteriia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_1552755_3	745718.JADT01000008_gene3137	2.88e-62	192.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1I20H@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_875930_1	62928.azo3057	5.34e-133	387.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,2KVI4@206389|Rhodocyclales	206389|Rhodocyclales	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
k59_931643_1	563040.Saut_1527	4.12e-88	270.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2YME3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_762352_1	688270.Celal_1775	1.16e-130	389.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
k59_762352_2	1197477.IA57_04795	4.25e-104	306.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1HXI2@117743|Flavobacteriia	976|Bacteroidetes	K	dependent repressor	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k59_762352_3	1380600.AUYN01000007_gene3293	1.01e-59	185.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_1206548_1	929558.SMGD1_0883	1.08e-79	254.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_764348_1	497321.C664_12195	1.83e-36	135.0	COG2518@1|root,COG2518@2|Bacteria,1QVT6@1224|Proteobacteria,2VV6Q@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_764348_2	1510531.JQJJ01000008_gene3923	2.32e-15	77.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria,2U314@28211|Alphaproteobacteria,3K61A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_877902_2	867900.Celly_1675	7.38e-42	142.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia,1F8SY@104264|Cellulophaga	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
k59_1782942_1	498211.CJA_2160	2.33e-56	196.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1FG7D@10|Cellvibrio	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_933398_1	616991.JPOO01000001_gene2783	3.23e-159	457.0	COG5434@1|root,COG5434@2|Bacteria,4NEM8@976|Bacteroidetes,1I07Y@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Glyco_hydro_88,Pectate_lyase_3
k59_933398_2	1392490.JHZX01000001_gene2033	1.32e-63	204.0	COG4225@1|root,COG4225@2|Bacteria,4NIET@976|Bacteroidetes,1I0HZ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861
k59_711155_1	1123518.ARWI01000001_gene1211	5.05e-18	82.4	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_711155_2	1123518.ARWI01000001_gene1210	7.42e-71	219.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_1102951_2	326298.Suden_1755	2.93e-48	160.0	COG1057@1|root,COG1057@2|Bacteria,1NG4J@1224|Proteobacteria,42P0F@68525|delta/epsilon subdivisions,2YMQR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,RsfS
k59_29407_2	1123518.ARWI01000001_gene572	1.92e-54	175.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,460XZ@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_764414_1	1123514.KB905899_gene1300	1.82e-13	69.7	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,460D4@72273|Thiotrichales	72273|Thiotrichales	S	Cupin superfamily protein	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
k59_764414_2	517417.Cpar_0567	2.75e-35	129.0	COG2602@1|root,COG2602@2|Bacteria,1FE67@1090|Chlorobi	1090|Chlorobi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
k59_368880_1	225849.swp_3897	1.56e-47	160.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,2Q8SF@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Pribosyl_synth,Pribosyltran_N
k59_652611_1	411154.GFO_0806	6.07e-71	219.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia	976|Bacteroidetes	D	chromosome partitioning	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_652611_2	411154.GFO_0808	6e-22	91.7	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,1HWS3@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
k59_200891_1	1123518.ARWI01000001_gene2395	9.46e-24	100.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,460A4@72273|Thiotrichales	72273|Thiotrichales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_200891_2	1168067.JAGP01000001_gene937	2.22e-22	95.5	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,460J2@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_87797_1	1121931.AUHG01000011_gene2203	8.24e-94	287.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,1HWVE@117743|Flavobacteriia	976|Bacteroidetes	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_1669271_1	1121931.AUHG01000018_gene1408	1.18e-138	400.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1669271_2	411154.GFO_0275	1.15e-160	459.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_1442052_1	273121.WS0950	8.7e-17	79.7	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1442052_2	929558.SMGD1_2128	1.7e-103	304.0	2BNSM@1|root,32HG6@2|Bacteria,1Q1E8@1224|Proteobacteria,42TDY@68525|delta/epsilon subdivisions,2YPGN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1442052_3	929558.SMGD1_2127	7.99e-93	273.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_1669286_1	572480.Arnit_1775	3.03e-57	180.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42U2T@68525|delta/epsilon subdivisions,2YPV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1669286_2	572480.Arnit_1774	2.3e-27	110.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2YMFS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_1500203_1	616991.JPOO01000001_gene4406	6.23e-61	192.0	COG3345@1|root,COG3345@2|Bacteria,4NFSU@976|Bacteroidetes,1HZSR@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
k59_87825_1	1121931.AUHG01000010_gene648	7.05e-101	301.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes,1HY6U@117743|Flavobacteriia	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_539198_1	357276.EL88_23535	8.07e-219	658.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_764480_1	1353276.JADR01000003_gene2832	4.12e-18	78.6	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_764480_2	1137281.D778_02415	1.14e-98	291.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1HXD3@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_29456_1	981336.F944_00388	4.82e-12	65.1	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,3NJ8P@468|Moraxellaceae	1236|Gammaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_29456_2	717773.Thicy_0167	2.42e-47	152.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,4618C@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_29456_3	90814.KL370891_gene289	7.36e-64	195.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,460ZR@72273|Thiotrichales	72273|Thiotrichales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k59_29456_4	90814.KL370891_gene288	1.01e-183	516.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_29456_5	90814.KL370891_gene287	1.92e-71	222.0	2C2GB@1|root,34B2T@2|Bacteria,1P3HZ@1224|Proteobacteria,1SRRW@1236|Gammaproteobacteria,462ZV@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_29456_6	497321.C664_01530	6.1e-58	207.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVVB@206389|Rhodocyclales	206389|Rhodocyclales	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1
k59_1725718_1	29540.C481_09422	3.76e-08	55.5	COG1321@1|root,arCOG02099@2157|Archaea,2XSWC@28890|Euryarchaeota,23S1S@183963|Halobacteria	183963|Halobacteria	K	COG1321 Mn-dependent transcriptional regulator	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k59_1725718_2	1123514.KB905899_gene637	2.09e-70	220.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1108 ABC-type Mn2 Zn2 transport systems permease components	yfeD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071944	-	ko:K09819,ko:K11606,ko:K11709	ko02010,map02010	M00243,M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	iEC042_1314.EC042_1518	ABC-3
k59_1614147_1	929558.SMGD1_0378	9.45e-61	208.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1442098_1	1123514.KB905901_gene137	2.83e-127	372.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,45ZRM@72273|Thiotrichales	72273|Thiotrichales	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_595247_1	655815.ZPR_2335	8.93e-55	180.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_823044_1	929558.SMGD1_1219	5.74e-40	136.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,42M91@68525|delta/epsilon subdivisions,2YMTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_823044_2	929558.SMGD1_1220	1.17e-59	200.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1442105_1	411154.GFO_1769	8.83e-34	131.0	COG4219@1|root,COG4219@2|Bacteria,4NHAY@976|Bacteroidetes,1HXH6@117743|Flavobacteriia	976|Bacteroidetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
k59_1442105_2	1107311.Q767_14100	7.05e-35	122.0	COG3682@1|root,COG3682@2|Bacteria,4NP4S@976|Bacteroidetes,1I229@117743|Flavobacteriia,2NWBX@237|Flavobacterium	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_1554814_1	1178825.ALIH01000007_gene1612	6.61e-92	275.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1HX4S@117743|Flavobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_951217_1	563040.Saut_0197	3.8e-45	152.0	COG0433@1|root,COG0433@2|Bacteria,1Q4H7@1224|Proteobacteria,42Z6M@68525|delta/epsilon subdivisions,2YR7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_951217_2	929558.SMGD1_1013	1.45e-12	66.6	COG0794@1|root,COG2905@1|root,COG0794@2|Bacteria,COG2905@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_1227016_1	929558.SMGD1_1041	2.24e-113	335.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	ptmE	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k59_1227016_2	1537915.JU57_06730	9.51e-47	158.0	COG0535@1|root,COG0535@2|Bacteria,1PDXU@1224|Proteobacteria,42NVS@68525|delta/epsilon subdivisions,2YNBB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
k59_786369_1	411154.GFO_2354	6.89e-106	317.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1HX29@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
k59_1294515_1	1121931.AUHG01000011_gene2254	1.43e-183	523.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1353460_1	411154.GFO_2351	4.43e-68	214.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HZNF@117743|Flavobacteriia	976|Bacteroidetes	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DUF3887,Hydrolase_4
k59_1353460_2	411154.GFO_2352	2.55e-29	104.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1I51F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
k59_1747745_1	1123518.ARWI01000001_gene1127	1.94e-102	300.0	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,461V2@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_1522267_1	317025.Tcr_1148	4.07e-68	223.0	2DM3X@1|root,31MK7@2|Bacteria,1RFI0@1224|Proteobacteria,1S7WP@1236|Gammaproteobacteria,462FZ@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_614391_1	563040.Saut_1111	3.5e-78	261.0	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CEC@68525|delta/epsilon subdivisions,2YTBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_390321_1	1178825.ALIH01000009_gene1324	1.55e-105	315.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_1690869_2	563040.Saut_1800	3.24e-52	176.0	COG4968@1|root,COG4968@2|Bacteria,1QUIY@1224|Proteobacteria,42S53@68525|delta/epsilon subdivisions,2YPC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_1405222_1	326298.Suden_0080	3.32e-66	211.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2YMKQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_1405222_2	563040.Saut_1967	4.02e-108	313.0	COG2952@1|root,COG2952@2|Bacteria,1PBRU@1224|Proteobacteria,42MEP@68525|delta/epsilon subdivisions,2YN8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
k59_1522308_1	317025.Tcr_0854	2.63e-132	399.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_390341_1	1121935.AQXX01000142_gene2326	1.06e-24	107.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1522309_1	1408473.JHXO01000010_gene3740	5.8e-42	149.0	COG1470@1|root,COG1470@2|Bacteria,4NHIX@976|Bacteroidetes,2FN9I@200643|Bacteroidia	976|Bacteroidetes	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
k59_1462467_1	398579.Spea_3366	7.94e-114	335.0	COG3203@1|root,COG3203@2|Bacteria,1QSKG@1224|Proteobacteria,1RW30@1236|Gammaproteobacteria,2Q9W6@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM porin Gram-negative type	-	-	-	-	-	-	-	-	-	-	-	-	Porin_1
k59_1066944_1	140626.JHWB01000009_gene1391	6.31e-18	80.9	2DBP0@1|root,2ZA6P@2|Bacteria,1V58E@1239|Firmicutes,24GG5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1068812_2	643867.Ftrac_1880	0.000209	44.3	COG0300@1|root,COG0300@2|Bacteria,4NIAI@976|Bacteroidetes,47MJU@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k59_900237_1	1484460.JSWG01000001_gene2291	7.71e-46	154.0	2DTB4@1|root,32UUV@2|Bacteria,4NSRC@976|Bacteroidetes,1I40G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_900237_2	655815.ZPR_1917	3.06e-122	352.0	COG0745@1|root,COG0745@2|Bacteria,4NGI5@976|Bacteroidetes,1HZWI@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1577083_1	743722.Sph21_3182	1.31e-34	123.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1IP8P@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1577083_2	1191523.MROS_0929	1.08e-19	85.5	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Imp-YgjV
k59_1577083_3	1229487.AMYW01000035_gene3117	8.35e-142	403.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia	976|Bacteroidetes	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_1577083_4	1178825.ALIH01000001_gene2468	1.1e-45	164.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1IJ95@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1009502_1	929558.SMGD1_0339	1.21e-97	305.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_676393_1	1121106.JQKB01000021_gene1767	7.63e-86	264.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2JPY3@204441|Rhodospirillales	204441|Rhodospirillales	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_1355464_1	1172190.M947_04760	2.15e-110	328.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2YMCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1692780_1	1380600.AUYN01000006_gene668	1.17e-105	316.0	COG2819@1|root,COG2819@2|Bacteria,4NGS5@976|Bacteroidetes,1HYN9@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_278111_1	1121931.AUHG01000010_gene878	3.41e-108	318.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1HX10@117743|Flavobacteriia	976|Bacteroidetes	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_506257_1	1487923.DP73_00155	3.64e-07	52.4	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,263UM@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, luxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_22,GerE
k59_506257_2	929558.SMGD1_2206	1.82e-82	263.0	2EPTW@1|root,33HED@2|Bacteria,1NK6N@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1229050_1	323850.Shew_0876	1.61e-117	357.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QA9N@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_1355474_2	1123518.ARWI01000001_gene2110	1.53e-144	410.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,45ZRE@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_676416_1	864073.HFRIS_020896	4.55e-79	249.0	COG0446@1|root,COG1773@1|root,COG0446@2|Bacteria,COG1773@2|Bacteria,1NR3M@1224|Proteobacteria,2VMGS@28216|Betaproteobacteria,472MK@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	rubB	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Rubredoxin
k59_842981_1	1123514.KB905900_gene2244	4.28e-57	177.0	COG0636@1|root,COG0636@2|Bacteria,1R359@1224|Proteobacteria,1T63K@1236|Gammaproteobacteria,461DV@72273|Thiotrichales	72273|Thiotrichales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_842981_2	317025.Tcr_2169	7.67e-39	136.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales	72273|Thiotrichales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_842981_3	1123518.ARWI01000001_gene1503	1.88e-83	251.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,46125@72273|Thiotrichales	72273|Thiotrichales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_842981_4	317025.Tcr_2167	2.15e-07	51.2	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_111728_2	869213.JCM21142_41795	5.29e-79	239.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,47JJZ@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_1229082_1	1172190.M947_03520	9.68e-106	330.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1464426_1	1172190.M947_04875	9.62e-59	196.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_788385_1	326298.Suden_1043	1.85e-87	281.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1692839_1	641526.ADIWIN_2876	5.13e-76	251.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_1229098_1	504487.JCM19302_4100	2.04e-10	66.2	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1229098_2	179408.Osc7112_2875	1.15e-07	53.5	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G2A7@1117|Cyanobacteria,1H9SV@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
k59_1464439_1	1121931.AUHG01000002_gene915	6.78e-75	251.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1631389_2	929558.SMGD1_2805	1.27e-62	202.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_1692853_1	1172190.M947_05505	1.66e-78	241.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,42R2I@68525|delta/epsilon subdivisions,2YP1Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_1692853_2	1165841.SULAR_03302	1.04e-29	108.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2YP7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k59_1464461_2	1178825.ALIH01000003_gene2021	1.33e-49	162.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1HYCZ@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_788445_1	1172190.M947_07025	6.39e-58	182.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2YNZC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_1296746_1	1121887.AUDK01000004_gene348	4.09e-107	324.0	COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1HYVZ@117743|Flavobacteriia,2NWZW@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_1631423_1	1123514.KB905899_gene1338	2.45e-61	204.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,45ZW3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1692901_1	211586.SO_2919	3.4e-32	120.0	COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,2Q9VN@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1692901_2	319224.Sputcn32_2386	1.68e-24	100.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,2Q9SD@267890|Shewanellaceae	1236|Gammaproteobacteria	S	AI-2E family transporter	tqsA	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
k59_1464511_1	616991.JPOO01000001_gene3931	5.06e-147	432.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1IJ95@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1296770_1	62928.azo1446	8.06e-53	167.0	2AX91@1|root,31P80@2|Bacteria,1N25K@1224|Proteobacteria,2VUB6@28216|Betaproteobacteria,2KX9N@206389|Rhodocyclales	206389|Rhodocyclales	N	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways	flhD	-	-	ko:K02403	ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlhD
k59_1183508_1	1172190.M947_10265	2.16e-294	812.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2YMGS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_1183508_2	749222.Nitsa_1009	7.15e-24	98.2	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_337432_1	1443665.JACA01000034_gene2469	1.93e-126	382.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2YH9I@290174|Aquimarina	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_676529_1	1380600.AUYN01000008_gene3439	5.07e-103	330.0	COG4932@1|root,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_676530_1	1380600.AUYN01000003_gene213	9.64e-25	95.1	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1I3Q8@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_676530_2	1137281.D778_02476	1.19e-80	244.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1HXCX@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_224068_1	411154.GFO_3165	1.06e-07	52.4	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_224068_2	411154.GFO_3166	2.49e-48	167.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1HXFR@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_900405_1	1178825.ALIH01000004_gene2845	1.56e-92	272.0	COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,1I1BH@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k59_900405_2	983544.Lacal_1925	3.39e-35	125.0	COG2860@1|root,COG2860@2|Bacteria,4NEXS@976|Bacteroidetes,1HX20@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_616477_1	1355368.JART01000002_gene2274	2.5e-103	311.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QAG@68525|delta/epsilon subdivisions,2YNQV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k59_616486_1	1234364.AMSF01000010_gene508	4.47e-26	109.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria,1X4ZQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k59_1183536_1	338963.Pcar_2424	8.44e-29	112.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,43SI5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_1183536_2	35725.K2S3W2	2.67e-11	63.2	COG0082@1|root,KOG4492@2759|Eukaryota,38EIY@33154|Opisthokonta,3NUJB@4751|Fungi,3QJS2@4890|Ascomycota,1ZXKN@147541|Dothideomycetes	4751|Fungi	E	Chorismate synthase	ARO2	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_1692948_1	323850.Shew_2821	8.57e-119	346.0	COG4785@1|root,COG4785@2|Bacteria,1N02Y@1224|Proteobacteria,1RP8P@1236|Gammaproteobacteria,2Q8P2@267890|Shewanellaceae	1236|Gammaproteobacteria	S	May be involved in cell division	nlpI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_8
k59_1009695_1	1121931.AUHG01000011_gene2431	2.21e-10	62.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
k59_1009695_2	1121931.AUHG01000011_gene2430	2.42e-60	207.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
k59_953017_1	679897.HMU07860	6.42e-31	112.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2YP4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_953017_2	563040.Saut_0203	3.5e-34	128.0	COG2208@1|root,COG2208@2|Bacteria,1P8H1@1224|Proteobacteria,43CBP@68525|delta/epsilon subdivisions,2YNYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg,SpoIIE
k59_1692964_1	1121904.ARBP01000016_gene5192	3.51e-05	51.2	COG0642@1|root,COG2205@2|Bacteria,4NQHU@976|Bacteroidetes,47R06@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
k59_676584_1	1172190.M947_01715	5.53e-57	194.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,43CEF@68525|delta/epsilon subdivisions,2YTC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1069043_1	1232410.KI421412_gene91	7.65e-30	112.0	2D254@1|root,32TC3@2|Bacteria,1N3UX@1224|Proteobacteria,42UIH@68525|delta/epsilon subdivisions,2WQAK@28221|Deltaproteobacteria,43SNV@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1069043_2	269799.Gmet_1267	1.33e-21	92.4	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,43TSK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_1296851_1	1380600.AUYN01000007_gene3212	2.57e-71	224.0	COG3021@1|root,COG3021@2|Bacteria,4NRTA@976|Bacteroidetes,1I2WS@117743|Flavobacteriia	976|Bacteroidetes	S	interspecies interaction between organisms	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_392471_1	398720.MED217_04192	1.61e-13	68.6	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,1HY0B@117743|Flavobacteriia,2XHUY@283735|Leeuwenhoekiella	976|Bacteroidetes	J	S4 RNA-binding domain	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_392471_2	1137281.D778_01064	3.47e-110	326.0	COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IJ6A@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
k59_843154_2	1121912.AUHD01000012_gene834	9.22e-244	695.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1HYKS@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
k59_843154_3	1178825.ALIH01000002_gene1014	6.07e-103	306.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_560774_1	1235803.C825_01966	1.57e-29	125.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,22X7J@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_560774_2	1450525.JATV01000009_gene745	4.67e-147	429.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1HWRF@117743|Flavobacteriia,2NU9G@237|Flavobacterium	976|Bacteroidetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_460587_2	1123518.ARWI01000001_gene2372	4.68e-56	178.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,4628I@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k59_629817_1	317025.Tcr_0622	1.01e-45	158.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,4606I@72273|Thiotrichales	72273|Thiotrichales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_629817_2	317025.Tcr_0621	2.44e-12	67.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31
k59_629817_3	1123518.ARWI01000001_gene2150	3.45e-123	360.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,45ZYD@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_403902_1	1121931.AUHG01000010_gene334	3.78e-124	360.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1HX72@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1646673_1	62928.azo3646	1.84e-96	302.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KUHK@206389|Rhodocyclales	206389|Rhodocyclales	U	Type 4 fimbrial biogenesis protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1250563_1	1380600.AUYN01000001_gene2687	7.81e-55	182.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1250563_2	1347342.BN863_7710	2.7e-53	182.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
k59_178232_1	1178825.ALIH01000016_gene602	9.03e-121	350.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_1648062_1	1484460.JSWG01000001_gene2154	2.32e-191	543.0	COG2031@1|root,COG2031@2|Bacteria,4NIRP@976|Bacteroidetes,1HWM3@117743|Flavobacteriia	976|Bacteroidetes	I	Short chain fatty acid transporter	-	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
k59_1648062_2	1178825.ALIH01000010_gene423	1.07e-151	434.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,1HYCH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179664_1	411154.GFO_1816	1.17e-151	452.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_1591893_2	317025.Tcr_2033	1.78e-113	333.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria,460VB@72273|Thiotrichales	72273|Thiotrichales	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_1591893_3	929558.SMGD1_0693	8.44e-55	180.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,42ND0@68525|delta/epsilon subdivisions,2YP8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_236237_1	1232410.KI421426_gene1339	3.2e-69	219.0	COG0583@1|root,COG0583@2|Bacteria,1RJ58@1224|Proteobacteria,42Z8D@68525|delta/epsilon subdivisions,2WTXQ@28221|Deltaproteobacteria,43T9Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_856563_1	929558.SMGD1_0707	1.46e-57	197.0	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1591916_1	929558.SMGD1_2432	1.85e-113	333.0	COG1565@1|root,COG1565@2|Bacteria,1QNDB@1224|Proteobacteria,42MQ8@68525|delta/epsilon subdivisions,2YNBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
k59_1082140_1	504472.Slin_3451	3.95e-71	223.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_292264_1	1121931.AUHG01000011_gene2388	7.41e-45	160.0	COG1352@1|root,COG2201@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HWYQ@117743|Flavobacteriia	976|Bacteroidetes	T	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
k59_292264_2	1121931.AUHG01000011_gene2389	3.14e-56	194.0	COG4251@1|root,COG4251@2|Bacteria,4NDUQ@976|Bacteroidetes,1HZ8B@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
k59_1309564_1	1168067.JAGP01000001_gene1922	7.61e-84	256.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,460QA@72273|Thiotrichales	72273|Thiotrichales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_1648096_1	1121875.KB907547_gene3142	5.07e-12	63.2	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_1648096_2	1121875.KB907547_gene3141	3.08e-111	321.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_1138896_1	317025.Tcr_1021	2.5e-10	60.5	COG2199@1|root,COG2199@2|Bacteria,1R4XN@1224|Proteobacteria,1RQ6S@1236|Gammaproteobacteria,461US@72273|Thiotrichales	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
k59_1138896_2	1280944.HY17_16955	8.18e-45	157.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF,Protoglobin
k59_688243_1	1484460.JSWG01000001_gene2150	1.71e-87	265.0	COG3631@1|root,COG3631@2|Bacteria,4NPKS@976|Bacteroidetes,1I2EQ@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL,SnoaL_2
k59_1648111_1	411154.GFO_1460	5.41e-130	393.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_1648111_2	411154.GFO_1461	2.74e-43	145.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HX5F@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_405373_1	1123517.JOMR01000001_gene1080	4.49e-32	126.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,45ZUV@72273|Thiotrichales	72273|Thiotrichales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_405373_2	1123518.ARWI01000001_gene240	6.9e-72	223.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,45ZWH@72273|Thiotrichales	72273|Thiotrichales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1252012_1	1137281.D778_01031	1.71e-57	187.0	COG1705@1|root,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1HYCP@117743|Flavobacteriia	976|Bacteroidetes	NU	Mannosyl-glycoprotein	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
k59_1252012_2	504487.JCM19302_484	7.13e-157	446.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,1HXPQ@117743|Flavobacteriia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
k59_1252015_1	1237149.C900_01035	2.33e-29	112.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_292303_1	1191523.MROS_0017	2.01e-69	221.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
k59_236300_1	1123514.KB905899_gene1319	1.17e-123	386.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,4602D@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1648129_2	1380600.AUYN01000001_gene2422	1.74e-135	394.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1HY8U@117743|Flavobacteriia	976|Bacteroidetes	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1478275_1	1123518.ARWI01000001_gene1716	1.16e-156	451.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,45ZZY@72273|Thiotrichales	72273|Thiotrichales	C	Malic enzyme, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Malic_M,malic
k59_1252031_1	411154.GFO_2051	3.41e-106	329.0	COG2203@1|root,COG2203@2|Bacteria,4NE84@976|Bacteroidetes,1HXM4@117743|Flavobacteriia	976|Bacteroidetes	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1252031_2	411154.GFO_2052	9.79e-201	563.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
k59_66553_2	1121904.ARBP01000064_gene2858	9.56e-37	131.0	2E69U@1|root,330XR@2|Bacteria,4NV70@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1026890_1	929558.SMGD1_2755	8.85e-101	294.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2YNVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_1704471_1	1123367.C666_08310	3.01e-100	306.0	COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,2VHJX@28216|Betaproteobacteria,2KY0W@206389|Rhodocyclales	206389|Rhodocyclales	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
k59_1364564_1	742727.HMPREF9447_00816	4.57e-69	220.0	COG1086@1|root,COG1086@2|Bacteria,4NGN2@976|Bacteroidetes,2FMXJ@200643|Bacteroidia,4AMB4@815|Bacteroidaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
k59_292343_1	1406840.Q763_00540	4.61e-66	209.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1HX0R@117743|Flavobacteriia,2NT5N@237|Flavobacterium	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k59_292343_2	1450525.JATV01000004_gene13	3.93e-21	91.7	2EVID@1|root,33NYK@2|Bacteria,4NZJB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_348182_1	1237149.C900_03021	1.14e-55	187.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_236355_1	323850.Shew_3700	1.36e-48	166.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,1RPY4@1236|Gammaproteobacteria,2Q8T8@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM glycosyl transferase group 1	rfaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_236355_2	323850.Shew_3701	5.98e-92	281.0	COG1819@1|root,COG1819@2|Bacteria,1PJJ9@1224|Proteobacteria,1S07B@1236|Gammaproteobacteria,2QAWF@267890|Shewanellaceae	1236|Gammaproteobacteria	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1648190_1	90814.KL370891_gene1668	5.52e-121	366.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,45ZS2@72273|Thiotrichales	72273|Thiotrichales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
k59_66594_1	1123514.KB905899_gene1021	1.68e-112	332.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,45ZSU@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1761241_1	929558.SMGD1_2357	1.76e-12	66.6	COG0591@1|root,COG0591@2|Bacteria,1MWX6@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	mctP	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_1761241_3	1172190.M947_08855	1.07e-26	106.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_913365_1	380394.Lferr_0208	1.46e-33	120.0	COG0640@1|root,COG0640@2|Bacteria,1PFJG@1224|Proteobacteria,1SWTI@1236|Gammaproteobacteria,2NE3E@225057|Acidithiobacillales	225057|Acidithiobacillales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	-
k59_405464_1	1121931.AUHG01000012_gene2538	1.27e-134	406.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_688340_1	1120999.JONM01000001_gene1035	4.54e-33	127.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,2VH7J@28216|Betaproteobacteria,2KU5P@206351|Neisseriales	206351|Neisseriales	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_1478334_1	563040.Saut_0636	9.83e-274	756.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_405471_1	563040.Saut_0002	1.25e-91	278.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2YM9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_856703_1	944546.ABED_1427	4.97e-47	171.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1NU9A@1224|Proteobacteria,42YSZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,dCache_2
k59_66625_1	85643.Tmz1t_3346	1.03e-47	155.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,2KWTF@206389|Rhodocyclales	206389|Rhodocyclales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_66625_2	1123367.C666_15870	4.37e-06	47.4	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,2KV0Q@206389|Rhodocyclales	206389|Rhodocyclales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_856707_1	572480.Arnit_0688	1.17e-57	190.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2YMBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_856707_2	572480.Arnit_0689	2.75e-78	235.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,43AUB@68525|delta/epsilon subdivisions,2YT3I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1139031_1	497321.C664_05061	2.29e-38	136.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,2KVBZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1139031_2	305700.B447_01411	1.31e-55	174.0	COG2944@1|root,COG2944@2|Bacteria,1N48U@1224|Proteobacteria,2VUHQ@28216|Betaproteobacteria,2KWYQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
k59_743917_2	1168067.JAGP01000001_gene538	1.44e-63	201.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,460ME@72273|Thiotrichales	72273|Thiotrichales	O	O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1478379_1	929558.SMGD1_1962	5.4e-15	72.8	COG0515@1|root,COG0515@2|Bacteria,1R91D@1224|Proteobacteria,42XMS@68525|delta/epsilon subdivisions,2YT4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_1478379_2	929558.SMGD1_1963	8.97e-130	372.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42QJR@68525|delta/epsilon subdivisions,2YNSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_743929_1	1122236.KB905147_gene2112	4.76e-120	381.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KM55@206350|Nitrosomonadales	206350|Nitrosomonadales	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_574896_2	1121931.AUHG01000018_gene1451	1.09e-57	180.0	2E5YZ@1|root,32W4Y@2|Bacteria,4NTRV@976|Bacteroidetes,1I451@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_574896_3	1137281.D778_00500	7.74e-55	176.0	2C59T@1|root,305DH@2|Bacteria,4NNXD@976|Bacteroidetes,1I259@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1592107_1	1121931.AUHG01000012_gene2897	1.14e-81	245.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1HZSH@117743|Flavobacteriia	976|Bacteroidetes	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_1193440_1	411154.GFO_1644	1.15e-141	438.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1592117_1	929558.SMGD1_1581	3.38e-128	384.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_801128_1	1168067.JAGP01000001_gene539	1.67e-49	173.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_801128_3	90814.KL370891_gene1470	2.18e-67	206.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,460MP@72273|Thiotrichales	72273|Thiotrichales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_801128_4	717773.Thicy_1427	7.2e-33	114.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,4616U@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_801128_5	90814.KL370891_gene1468	3.02e-65	200.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,460T7@72273|Thiotrichales	72273|Thiotrichales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_801128_6	743720.Psefu_2752	3.38e-20	89.7	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1YXM2@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN746.PP_2469	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1252164_1	929558.SMGD1_0822	4.89e-202	563.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2YN4H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_1309762_1	411154.GFO_0279	9.43e-37	127.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
k59_1309762_2	1121931.AUHG01000018_gene1402	1.01e-86	257.0	COG0262@1|root,COG0262@2|Bacteria,4NTP8@976|Bacteroidetes,1I3X6@117743|Flavobacteriia	976|Bacteroidetes	H	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
k59_1309762_3	1121931.AUHG01000018_gene1401	9.22e-57	186.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,1HZ16@117743|Flavobacteriia	976|Bacteroidetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_462341_1	519989.ECTPHS_08276	1.54e-36	125.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales	135613|Chromatiales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1478422_1	1172190.M947_09750	1.2e-54	172.0	29NSE@1|root,309QF@2|Bacteria,1QT0N@1224|Proteobacteria,42TIY@68525|delta/epsilon subdivisions,2YP79@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1478422_2	929558.SMGD1_2193	3.31e-73	228.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2YM9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,ParA
k59_1607864_1	679937.Bcop_1848	2.12e-15	82.8	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,2FM9K@200643|Bacteroidia,4AKKD@815|Bacteroidaceae	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_1379338_1	411154.GFO_3590	1.79e-106	320.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_420394_1	94122.Shewana3_3661	2.92e-23	99.4	COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,1S9QX@1236|Gammaproteobacteria,2QB2Q@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SMART Tetratricopeptide domain protein	mshN	-	-	ko:K12284	-	-	-	-	ko00000,ko02044	-	-	-	TPR_16,TPR_19
k59_420394_2	323850.Shew_0392	1.29e-42	154.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2Q8MY@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	General secretory system II, protein E domain protein	mshE	-	-	ko:K12276	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	T2SSE,T2SSE_N
k59_23721_1	62928.azo0622	1.53e-27	111.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VMZD@28216|Betaproteobacteria,2KYI4@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3
k59_23721_2	497321.C664_15938	4.64e-55	182.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2VHK0@28216|Betaproteobacteria,2KUE4@206389|Rhodocyclales	206389|Rhodocyclales	G	Malonyl-CoA decarboxylase N-terminal domain	-	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
k59_927829_1	572480.Arnit_3132	3.2e-56	188.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_927829_2	1348338.ADILRU_1840	1.01e-05	46.6	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FKGJ@85023|Microbacteriaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_980021_1	1033802.SSPSH_001224	4.53e-54	178.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Peptidyl-prolyl cis-trans	fkpA	GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042026,GO:0042597,GO:0044464	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_1325394_1	1380600.AUYN01000009_gene1911	2.43e-50	178.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1325394_2	313594.PI23P_00370	2.67e-14	71.6	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia,3VV07@52959|Polaribacter	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_195028_1	592029.DDD_2391	2.6e-126	369.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1HYEP@117743|Flavobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
k59_816781_1	247633.GP2143_04575	2.03e-10	62.4	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S764@1236|Gammaproteobacteria,1J68R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2716 Glycine cleavage system regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_4,ACT_6
k59_1204232_1	1250005.PHEL85_2141	5.4e-280	783.0	COG0243@1|root,COG0243@2|Bacteria,4PIKC@976|Bacteroidetes,1ICDV@117743|Flavobacteriia,3VXCJ@52959|Polaribacter	976|Bacteroidetes	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_758453_1	411154.GFO_1763	5.7e-162	462.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_758453_2	411154.GFO_1762	2.18e-29	112.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1HYNA@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1097019_1	1565129.JSFF01000016_gene178	3.65e-125	362.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,2QA75@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_872086_1	1380600.AUYN01000001_gene2659	4.37e-214	612.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_872086_2	1121887.AUDK01000017_gene47	5.32e-72	226.0	COG1649@1|root,COG1649@2|Bacteria,4NGFW@976|Bacteroidetes,1HYGF@117743|Flavobacteriia,2NV55@237|Flavobacterium	976|Bacteroidetes	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015,GHL10
k59_816830_1	1123518.ARWI01000001_gene2405	1.14e-111	328.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,460ZA@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_816830_2	90814.KL370891_gene1317	3.88e-44	155.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,460B0@72273|Thiotrichales	72273|Thiotrichales	T	PFAM PhoH-like protein	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_81971_1	323850.Shew_1386	3.91e-89	281.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,2Q9IN@267890|Shewanellaceae	1236|Gammaproteobacteria	T	CheA signal transduction histidine	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_816832_1	675816.VIA_003917	1.06e-16	85.9	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XUN9@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_1153474_1	1172190.M947_04270	1.39e-116	342.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_589531_1	1056820.KB900640_gene285	5.11e-77	251.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,2PQ7K@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
k59_589531_2	944547.ABLL_0539	1.3e-47	174.0	COG2010@1|root,COG2010@2|Bacteria,1NG71@1224|Proteobacteria,42P5C@68525|delta/epsilon subdivisions,2YNRE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_646618_1	504487.JCM19302_3474	1.26e-291	801.0	COG0477@1|root,COG0477@2|Bacteria,4PKTJ@976|Bacteroidetes,1IJGN@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1.3	-	-	Sugar_tr
k59_646618_2	319236.JCM19294_1673	7.38e-306	835.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of D-xylose to D-xylulose	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
k59_646618_3	688270.Celal_2450	1.62e-99	302.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,1HXH0@117743|Flavobacteriia,1F87X@104264|Cellulophaga	976|Bacteroidetes	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1719831_1	1348657.M622_05550	2.84e-89	280.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2WHHS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_980086_1	1396141.BATP01000057_gene3061	9.2e-82	250.0	COG1116@1|root,COG1116@2|Bacteria,46TJD@74201|Verrucomicrobia,2ITUG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_704599_2	317025.Tcr_0024	6.54e-36	132.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,45ZU4@72273|Thiotrichales	72273|Thiotrichales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_646632_1	572480.Arnit_2256	8.14e-98	317.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YMRQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1436301_1	411154.GFO_1980	5.2e-105	333.0	COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,4PMSQ@976|Bacteroidetes,1HZN0@117743|Flavobacteriia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,PAS_9,Response_reg
k59_1379458_1	926559.JoomaDRAFT_2967	1.7e-285	795.0	COG1100@1|root,COG1100@2|Bacteria,4NHD1@976|Bacteroidetes,1HZW7@117743|Flavobacteriia	976|Bacteroidetes	L	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
k59_1379458_2	926559.JoomaDRAFT_2968	8.35e-190	532.0	2C0R3@1|root,32R7E@2|Bacteria,4NRMI@976|Bacteroidetes,1I3FV@117743|Flavobacteriia	976|Bacteroidetes	S	Putative  PD-(D/E)XK family member, (DUF4420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4420
k59_1436317_1	1249480.B649_09600	3.28e-06	48.9	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2YM8M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1436317_2	317025.Tcr_1421	2.22e-91	271.0	2ACDM@1|root,311Z0@2|Bacteria,1RFMN@1224|Proteobacteria,1S3S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1204300_1	1380600.AUYN01000001_gene2700	1.96e-188	541.0	COG0495@1|root,COG0495@2|Bacteria,4PKSC@976|Bacteroidetes,1IJEG@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
k59_1097105_1	929558.SMGD1_2586	1.52e-136	392.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2YMHR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_589594_1	1178825.ALIH01000003_gene2042	5.58e-46	151.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_589594_2	1353276.JADR01000003_gene2768	2.74e-23	91.3	2D460@1|root,32TGC@2|Bacteria,4NQMR@976|Bacteroidetes,1I4CI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1379475_1	926562.Oweho_0192	2.13e-42	157.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_1663510_1	879212.DespoDRAFT_00216	6.78e-61	197.0	COG0095@1|root,COG0095@2|Bacteria,1RI3T@1224|Proteobacteria,42SQP@68525|delta/epsilon subdivisions,2WQH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_1663510_2	387093.SUN_0965	6.69e-125	364.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2YNPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_23881_1	318167.Sfri_1180	1.18e-15	75.5	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2Q8YJ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_477588_1	1178825.ALIH01000009_gene1291	1.14e-100	301.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1HXGT@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_1719891_1	1441629.PCH70_02900	3.58e-13	72.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1S6MH@1236|Gammaproteobacteria,1Z7KU@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	TonB C terminal	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1494250_1	1033736.CAHK01000025_gene1503	3.92e-13	68.6	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4F9WU@85019|Brevibacteriaceae	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	yabJ	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
k59_1494250_2	945713.IALB_0817	9.07e-25	99.0	COG1694@1|root,COG3956@2|Bacteria	2|Bacteria	E	TIGRFAM MazG family protein	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG
k59_872222_1	1137281.D778_01957	4.07e-105	315.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_420590_1	1249975.JQLP01000003_gene188	1.25e-46	158.0	COG1043@1|root,COG1043@2|Bacteria,4NJC7@976|Bacteroidetes,1I24X@117743|Flavobacteriia,2P7IW@244698|Gillisia	976|Bacteroidetes	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_1325587_1	323850.Shew_1569	5.85e-81	246.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,2Q9WU@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_1325587_2	1307437.J139_05290	6.57e-14	71.2	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,2Q103@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1549090_1	326298.Suden_0914	2.1e-34	126.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,42KZV@68525|delta/epsilon subdivisions,2YM8J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	flgS	-	2.7.13.3	ko:K02482,ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1549090_2	1537917.JU82_02455	2.19e-15	77.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_1379530_1	1178825.ALIH01000007_gene1587	1.54e-109	352.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_533532_1	1197477.IA57_06255	1.07e-89	267.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_533532_2	1121912.AUHD01000006_gene1256	1.05e-48	164.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1HXAJ@117743|Flavobacteriia	976|Bacteroidetes	S	succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_872231_1	929558.SMGD1_1892	4.33e-111	326.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,43B2E@68525|delta/epsilon subdivisions,2YN33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	peptidylprolyl isomerase	peb4	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_704720_1	563040.Saut_0792	3.2e-107	322.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2YMS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_363018_1	90813.JQMT01000001_gene690	1.43e-62	204.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria,460K6@72273|Thiotrichales	72273|Thiotrichales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_363018_2	1168067.JAGP01000001_gene470	7.34e-61	194.0	COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,1S4JR@1236|Gammaproteobacteria,461H1@72273|Thiotrichales	72273|Thiotrichales	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
k59_589667_1	317025.Tcr_0901	4.59e-125	360.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,4604D@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_589667_2	317025.Tcr_0900	5.89e-31	123.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,460ZY@72273|Thiotrichales	72273|Thiotrichales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
k59_589667_3	317025.Tcr_0899	4.79e-43	147.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,460Y2@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_23940_1	411154.GFO_0394	5.3e-74	251.0	COG1345@1|root,COG1345@2|Bacteria,4NHMH@976|Bacteroidetes,1HZTE@117743|Flavobacteriia	976|Bacteroidetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
k59_646749_1	504487.JCM19302_3698	3.21e-122	357.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_1041833_1	319236.JCM19294_1125	1.43e-71	232.0	28JJ1@1|root,2Z9C5@2|Bacteria,4NJEU@976|Bacteroidetes,1I0KB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1097203_1	1121931.AUHG01000018_gene1364	1.22e-163	466.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1HXJC@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_137352_1	90814.KL370891_gene1854	7.02e-198	577.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_137352_2	391937.NA2_16103	2.33e-08	57.8	COG3915@1|root,COG3915@2|Bacteria,1RHJS@1224|Proteobacteria,2U8BH@28211|Alphaproteobacteria,43KRG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
k59_137352_3	90814.KL370892_gene2069	0.000276	42.4	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,45ZRR@72273|Thiotrichales	72273|Thiotrichales	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_758651_1	1121937.AUHJ01000022_gene1382	4.34e-24	107.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,4643B@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_137354_1	1249975.JQLP01000001_gene3448	7.06e-79	257.0	COG1196@1|root,COG3391@1|root,COG1196@2|Bacteria,COG3391@2|Bacteria,4NI6H@976|Bacteroidetes,1HXFZ@117743|Flavobacteriia	976|Bacteroidetes	DZ	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
k59_195267_1	411154.GFO_2079	5.03e-79	248.0	COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,1HYMN@117743|Flavobacteriia	976|Bacteroidetes	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k59_1325652_1	1190606.AJYG01000093_gene2025	7.54e-30	112.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1XU58@135623|Vibrionales	135623|Vibrionales	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH
k59_982096_1	827.JFJK01000002_gene1037	9.08e-12	70.5	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2YN49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II and III secretion system protein	ctsD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_1155674_1	572480.Arnit_2251	1.51e-40	147.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_422546_1	572480.Arnit_2890	1.49e-132	400.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2YN0Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD,NTP_transf_2
k59_254095_1	983920.Y88_1860	2.31e-06	52.8	COG0707@1|root,COG5017@1|root,COG0707@2|Bacteria,COG5017@2|Bacteria,1NMQ0@1224|Proteobacteria,2UQF9@28211|Alphaproteobacteria,2JZWW@204457|Sphingomonadales	204457|Sphingomonadales	M	Oligosaccharide biosynthesis protein Alg14 like	-	-	-	-	-	-	-	-	-	-	-	-	Alg14,Glyco_tran_28_C
k59_535414_1	1121931.AUHG01000010_gene133	1.29e-90	274.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HX79@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_760597_1	1492738.FEM21_24090	1.78e-22	99.4	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia,2P0MC@237|Flavobacterium	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_422556_2	62928.azo1428	8.76e-133	379.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria,2KVXH@206389|Rhodocyclales	206389|Rhodocyclales	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_139280_1	1123518.ARWI01000001_gene569	3.41e-134	390.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,45ZPQ@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1496287_1	563040.Saut_0280	1.02e-65	219.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2YN9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	ABC transporter	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
k59_760605_1	926556.Echvi_1230	2.35e-07	55.8	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_760605_2	929556.Solca_3704	3.5e-12	68.9	COG0521@1|root,COG0521@2|Bacteria,4NEQZ@976|Bacteroidetes,1J06W@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_439529_1	1123367.C666_10860	1.38e-10	56.2	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,2KXCI@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
k59_439529_2	62928.azo1470	2.41e-66	212.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KU8U@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1739282_1	1121931.AUHG01000011_gene1932	2.7e-112	349.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_269659_1	264462.Bd1692	3.31e-39	138.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2MU4D@213481|Bdellovibrionales,2WJFW@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_269659_2	1165841.SULAR_04978	4.77e-49	172.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,43DDC@68525|delta/epsilon subdivisions,2YNI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_382089_1	572480.Arnit_0494	7.93e-133	382.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2YMTQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_606870_1	519989.ECTPHS_12104	1.08e-22	96.7	COG0545@1|root,COG0607@1|root,COG0545@2|Bacteria,COG0607@2|Bacteria,1RDA1@1224|Proteobacteria,1S617@1236|Gammaproteobacteria,1WYIK@135613|Chromatiales	135613|Chromatiales	OP	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C,Rhodanese
k59_1286526_1	1232410.KI421421_gene3581	3.61e-78	248.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,43SE4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	CTP synthase N-terminus	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_1173281_1	929558.SMGD1_1060	5.91e-32	120.0	COG0475@1|root,COG0475@2|Bacteria,1N2RV@1224|Proteobacteria,43B2N@68525|delta/epsilon subdivisions,2YT5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_1173281_2	326298.Suden_0169	1.5e-40	141.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2YMH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k59_382111_1	1178825.ALIH01000010_gene440	5.27e-178	500.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1HXU5@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
k59_382111_2	1178825.ALIH01000010_gene439	7.06e-08	51.6	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1I189@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
k59_496458_1	864069.MicloDRAFT_00043700	3.7e-40	144.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2U8SM@28211|Alphaproteobacteria,1JTHS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	-
k59_1286555_2	305700.B447_00986	7.82e-74	225.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,2KV8C@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_382135_1	317025.Tcr_0128	9.88e-58	198.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,45ZUX@72273|Thiotrichales	72273|Thiotrichales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_382135_2	1033802.SSPSH_001334	4.31e-39	140.0	COG1136@1|root,COG1136@2|Bacteria,1RH0D@1224|Proteobacteria,1T21A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Pfam ABC	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_327197_1	563040.Saut_1551	4.71e-85	268.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2YMF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	ABC transporter	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_1116636_1	1121931.AUHG01000012_gene2500	1.28e-108	318.0	2DBB1@1|root,2Z854@2|Bacteria,4NNZD@976|Bacteroidetes,1I12G@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
k59_1739364_1	1380600.AUYN01000006_gene675	2.02e-159	474.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1739364_2	1197477.IA57_06200	4.01e-199	566.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_777886_1	1121931.AUHG01000010_gene559	8.47e-112	325.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia	976|Bacteroidetes	S	amidophosphoribosyl-transferase	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
k59_777886_2	411154.GFO_3531	3.3e-17	80.1	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
k59_777889_1	610130.Closa_3879	2.45e-15	82.0	COG0840@1|root,COG3437@1|root,COG0840@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,223RM@1506553|Lachnoclostridium	186801|Clostridia	T	Diguanylate cyclase and metal dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
k59_1625489_1	1178825.ALIH01000011_gene15	9.41e-194	554.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1059211_1	326297.Sama_1499	5.85e-37	137.0	28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria,2QAFH@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3360)	VV2341	-	-	-	-	-	-	-	-	-	-	-	DUF3360
k59_1059211_2	1056820.KB900629_gene1849	3.79e-35	130.0	COG0477@1|root,COG0477@2|Bacteria,1QZGP@1224|Proteobacteria,1T468@1236|Gammaproteobacteria,2PPS2@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_382183_1	1121904.ARBP01000007_gene3044	1.36e-111	327.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,47MY7@768503|Cytophagia	976|Bacteroidetes	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_606966_1	929558.SMGD1_0723	5.72e-90	267.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_606966_2	563040.Saut_1626	3.27e-14	68.6	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria,42VTZ@68525|delta/epsilon subdivisions,2YQJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k59_1796494_1	1286106.MPL1_08132	1.29e-128	391.0	COG0497@1|root,COG1121@1|root,COG0497@2|Bacteria,COG1121@2|Bacteria,1QUIQ@1224|Proteobacteria,1T3HA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
k59_1218774_1	748247.AZKH_3695	2.05e-116	341.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,2KUHH@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_550802_1	1168067.JAGP01000001_gene1112	8.38e-131	377.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,45ZU2@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_550802_2	90813.JQMT01000001_gene921	3.96e-56	181.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,45ZPM@72273|Thiotrichales	72273|Thiotrichales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_725096_1	1380600.AUYN01000007_gene3311	2.69e-236	672.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_1173401_1	637905.SVI_2000	1.37e-79	241.0	COG1989@1|root,COG1989@2|Bacteria,1R34Z@1224|Proteobacteria,1SBEI@1236|Gammaproteobacteria,2QA9C@267890|Shewanellaceae	1236|Gammaproteobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
k59_269791_1	90814.KL370891_gene1449	1.85e-194	544.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,45ZNY@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_1059256_1	504487.JCM19302_8	2.63e-20	89.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWJZ@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1345500_1	349163.Acry_2584	2.89e-22	96.3	COG3271@1|root,COG3271@2|Bacteria,1RHAJ@1224|Proteobacteria,2U9P7@28211|Alphaproteobacteria,2JX5F@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidase C39 family	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	Peptidase_C39
k59_1345500_2	318161.Sden_2966	4.48e-16	78.2	2ADV6@1|root,313M2@2|Bacteria,1PSND@1224|Proteobacteria,1TAV7@1236|Gammaproteobacteria,2QDXJ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_999534_1	563040.Saut_1750	6.28e-105	325.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_382240_1	1121931.AUHG01000017_gene1505	4.76e-245	673.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX09@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_382240_2	411154.GFO_1795	2.14e-66	219.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_101725_1	1172190.M947_10995	2.44e-20	84.3	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,42X5E@68525|delta/epsilon subdivisions,2YSGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_607016_1	1121019.AUMN01000001_gene917	8.28e-13	67.4	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,1W7W1@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_607016_2	945713.IALB_1567	9.81e-33	116.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	raiA	-	-	ko:K03733,ko:K05808,ko:K05809	-	-	-	-	ko00000,ko03009,ko03036	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_1739476_1	1116472.MGMO_8c00900	1.11e-84	258.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RRE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_42130_1	504487.JCM19302_4036	1.69e-13	68.6	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1HX5K@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
k59_42130_2	1380600.AUYN01000007_gene3055	1.1e-61	204.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1HWW3@117743|Flavobacteriia	976|Bacteroidetes	D	peptidase M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_778011_1	323850.Shew_1570	6.01e-15	70.5	COG3133@1|root,COG3133@2|Bacteria,1RIY9@1224|Proteobacteria,1S819@1236|Gammaproteobacteria,2QBYM@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM 17 kDa surface antigen	slyB	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
k59_778011_2	425104.Ssed_1891	1.65e-32	117.0	2E78H@1|root,331S5@2|Bacteria,1N81Y@1224|Proteobacteria,1SDJS@1236|Gammaproteobacteria,2QCPM@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156278_1	1506583.JQJY01000001_gene663	4.28e-26	109.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes,1I0D2@117743|Flavobacteriia,2NTN6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_999563_1	572480.Arnit_0275	2.95e-76	233.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2YRJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sugar fermentation stimulation protein	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_1516790_1	1178825.ALIH01000012_gene1843	1.89e-132	380.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_158639_2	1121878.AUGL01000008_gene1443	2.8e-71	236.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_727846_1	1380600.AUYN01000009_gene1911	1.67e-121	384.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1176114_1	62928.azo3521	1.29e-52	178.0	COG0501@1|root,COG0501@2|Bacteria,1QBCD@1224|Proteobacteria,2W1RW@28216|Betaproteobacteria,2KYBG@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_946960_1	1565129.JSFF01000021_gene623	5.34e-140	412.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,2QANX@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_727854_1	376686.Fjoh_2012	5.73e-255	734.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2NSP5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_727854_2	1348583.ATLH01000015_gene306	5.46e-37	128.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1I338@117743|Flavobacteriia,1FAI2@104264|Cellulophaga	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
k59_553547_1	497321.C664_11735	5.39e-132	383.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2VIVU@28216|Betaproteobacteria,2KXRT@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD binding domain	-	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
k59_217206_1	1380600.AUYN01000009_gene1684	1.48e-69	225.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_609379_2	375286.mma_3191	4.57e-37	133.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,4726M@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
k59_1400871_2	1178825.ALIH01000003_gene2194	1.6e-77	234.0	COG2128@1|root,COG2128@2|Bacteria,4NEJZ@976|Bacteroidetes,1HXPF@117743|Flavobacteriia	976|Bacteroidetes	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_104484_1	572480.Arnit_0223	2.56e-130	378.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2YN5Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_384956_1	1336233.JAEH01000015_gene3304	2.57e-23	95.5	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,2Q9A5@267890|Shewanellaceae	1236|Gammaproteobacteria	S	S1 domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_158688_1	1042376.AFPK01000071_gene712	7e-89	282.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia,405VS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1348268_1	1249480.B649_06535	5.18e-60	197.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2YNPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_1348268_2	709032.Sulku_1497	7.13e-171	489.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2YNM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k59_384980_2	563040.Saut_0985	4.34e-46	169.0	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_727907_1	1380600.AUYN01000003_gene121	2.9e-127	382.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1176181_1	1278309.KB907104_gene855	1.28e-82	249.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1S2VZ@1236|Gammaproteobacteria,1XJSF@135619|Oceanospirillales	135619|Oceanospirillales	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_1221650_1	946077.W5A_11434	5.74e-62	205.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
k59_1221650_3	1380600.AUYN01000009_gene1888	2.2e-86	256.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I1HX@117743|Flavobacteriia	976|Bacteroidetes	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
k59_1221650_4	1380600.AUYN01000009_gene1889	9.58e-65	207.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1289440_1	90814.KL370891_gene1834	2.65e-101	300.0	2CJ90@1|root,33RG4@2|Bacteria,1QQB1@1224|Proteobacteria,1SK60@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
k59_499360_1	314345.SPV1_11116	1.2e-25	100.0	COG3668@1|root,COG3668@2|Bacteria,1REHT@1224|Proteobacteria	1224|Proteobacteria	S	plasmid stabilization	-	GO:0002790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030255,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0043684,GO:0044097,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0097159,GO:1901363	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_1176187_1	1172190.M947_09725	2.3e-111	328.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_781035_2	1158345.JNLL01000001_gene1578	7.73e-12	66.2	2C5PA@1|root,34CE7@2|Bacteria,2G5GP@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_781035_3	572480.Arnit_1334	8.83e-36	126.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42UAU@68525|delta/epsilon subdivisions,2YNG0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_286820_1	1347342.BN863_29660	1.72e-128	374.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_795292_1	1001585.MDS_1914	4.83e-08	53.5	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RMZU@1236|Gammaproteobacteria,1YHA8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
k59_795292_2	497321.C664_07863	2.98e-68	213.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2VJQR@28216|Betaproteobacteria,2KXYZ@206389|Rhodocyclales	206389|Rhodocyclales	G	urate catabolism protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1586162_1	1122197.ATWI01000009_gene1539	1.66e-36	135.0	COG4748@1|root,COG4748@2|Bacteria,1MXDA@1224|Proteobacteria,1RSNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
k59_456481_1	1223410.KN050846_gene2697	6.68e-114	334.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1HXY0@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_4343_1	391598.FBBAL38_02090	2.38e-120	374.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_4343_2	1131812.JQMS01000001_gene2980	5.62e-44	145.0	2DZT3@1|root,32VI6@2|Bacteria,4NSPZ@976|Bacteroidetes,1I4KB@117743|Flavobacteriia,2NX3M@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1021308_1	1408433.JHXV01000034_gene5	6.82e-25	101.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia,2PBU0@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_1189756_2	1089547.KB913013_gene4668	2.01e-284	813.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_174053_1	1123518.ARWI01000001_gene1769	1.1e-44	145.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,460X2@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_174053_2	90814.KL370891_gene1870	2.35e-27	99.4	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_1586168_2	1127695.HMPREF9163_02223	1.54e-05	49.3	COG0848@1|root,COG0848@2|Bacteria,1V5RQ@1239|Firmicutes,4H4XU@909932|Negativicutes	909932|Negativicutes	U	Transport energizing protein, ExbD TolR family	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1586168_3	864702.OsccyDRAFT_5012	0.000121	45.8	COG0811@1|root,COG0811@2|Bacteria,1G09J@1117|Cyanobacteria,1H7PC@1150|Oscillatoriales	1117|Cyanobacteria	U	MotA TolQ ExbB proton channel	exbB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_682574_1	1121875.KB907547_gene3138	5.9e-32	123.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1I09M@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_682574_2	1279009.ADICEAN_01553	1.13e-211	588.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_1642726_1	1278309.KB907101_gene742	1.99e-30	117.0	COG5650@1|root,COG5650@2|Bacteria,1NT6Q@1224|Proteobacteria,1SKE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1642726_2	317025.Tcr_1509	2.86e-197	551.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,461ZA@72273|Thiotrichales	72273|Thiotrichales	M	NAD-dependent epimerase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_1642726_3	1442598.JABW01000022_gene2029	1.83e-07	51.6	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2YMID@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1698969_2	317025.Tcr_0015	9.31e-68	214.0	COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,1SA0V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k59_117321_1	323850.Shew_2440	3.7e-114	357.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q9QR@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1416485_1	411154.GFO_0784	3.23e-78	241.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1HX8A@117743|Flavobacteriia	976|Bacteroidetes	S	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
k59_1133987_1	563040.Saut_1360	1.5e-19	83.6	COG4314@1|root,COG4314@2|Bacteria,1N3G0@1224|Proteobacteria,42SNT@68525|delta/epsilon subdivisions,2YPPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1133987_2	563040.Saut_1361	3.63e-78	236.0	COG2206@1|root,COG2206@2|Bacteria,1PNPY@1224|Proteobacteria,430SC@68525|delta/epsilon subdivisions,2YS3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_1133987_3	326298.Suden_1247	9.93e-25	99.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2YT9X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerH	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1529250_1	1237149.C900_02564	1.3e-114	359.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47U10@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_399931_1	504487.JCM19302_3283	7.3e-97	291.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia	976|Bacteroidetes	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_1698986_1	323850.Shew_1810	1.32e-107	317.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,2Q9G0@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	DHO_dh
k59_1698987_1	1121931.AUHG01000017_gene1492	8.71e-114	355.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1698987_2	1121931.AUHG01000017_gene1491	1.14e-31	117.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia	976|Bacteroidetes	S	NADP oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
k59_60996_1	1137281.D778_02537	1.17e-81	262.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia	976|Bacteroidetes	EM	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
k59_851039_1	1123518.ARWI01000001_gene827	3.96e-199	570.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,45ZN8@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_4391_1	411154.GFO_3580	7.64e-152	454.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1HWNX@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF3991,Plug,TonB_dep_Rec,Toprim_2
k59_117349_1	1278307.KB906996_gene3035	1.24e-48	162.0	COG5514@1|root,COG5514@2|Bacteria,1MX90@1224|Proteobacteria,1S9SH@1236|Gammaproteobacteria,2QIQX@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
k59_342834_1	411154.GFO_2856	4.23e-29	114.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,1HYHT@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_342834_2	411154.GFO_2857	1.68e-40	139.0	2E7WJ@1|root,332B6@2|Bacteria,4NVEC@976|Bacteroidetes,1I555@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1586213_1	1408813.AYMG01000007_gene4295	4.53e-07	59.7	COG0614@1|root,COG0614@2|Bacteria,4NFDZ@976|Bacteroidetes	976|Bacteroidetes	P	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1586213_2	861299.J421_4131	1.56e-75	251.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
k59_1359459_1	62928.azo2535	8.19e-122	354.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,2KVKF@206389|Rhodocyclales	206389|Rhodocyclales	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1755663_1	929558.SMGD1_2807	1.15e-100	298.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2YMSU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motS	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_625846_1	326298.Suden_1316	2.15e-68	220.0	COG4591@1|root,COG4591@2|Bacteria,1QVSQ@1224|Proteobacteria,43BSZ@68525|delta/epsilon subdivisions,2YTAZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_512330_1	1278309.KB907099_gene2738	1.32e-19	85.5	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1XHUT@135619|Oceanospirillales	135619|Oceanospirillales	K	LuxR family	luxR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_344194_1	745718.JADT01000005_gene55	5.23e-145	414.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1078289_1	313603.FB2170_14818	5.86e-92	285.0	COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1247843_1	572480.Arnit_0784	3.04e-95	292.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1QZF4@1224|Proteobacteria,42R9Z@68525|delta/epsilon subdivisions,2YP2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_1247843_2	572480.Arnit_0783	2.21e-34	123.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
k59_627257_1	90814.KL370891_gene869	1.23e-112	336.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,45ZUI@72273|Thiotrichales	72273|Thiotrichales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_627257_2	90814.KL370891_gene868	2.97e-64	197.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria,462GA@72273|Thiotrichales	72273|Thiotrichales	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1530519_1	411154.GFO_3369	1.77e-117	347.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1078302_1	1380600.AUYN01000006_gene541	3.63e-20	89.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1HXNI@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1078302_2	1347342.BN863_31950	2.71e-71	220.0	COG0463@1|root,COG0463@2|Bacteria,4PM68@976|Bacteroidetes,1IJKP@117743|Flavobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_232051_1	411154.GFO_1629	2.41e-34	139.0	COG5002@1|root,COG5002@2|Bacteria,4PM0I@976|Bacteroidetes,1IJIA@117743|Flavobacteriia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9
k59_1078307_1	1121931.AUHG01000018_gene1447	1.96e-115	355.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_458007_1	1123514.KB905899_gene679	6e-78	246.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,4605J@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_458007_2	1123514.KB905899_gene678	6.99e-133	389.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4602R@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_909444_1	563040.Saut_0683	1.43e-157	462.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2YNTT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,TPR_8,VWA_2
k59_909444_2	1172190.M947_10940	3.17e-09	57.4	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_740029_1	1123514.KB905899_gene1503	1.21e-89	287.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales	72273|Thiotrichales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_627283_1	1484460.JSWG01000015_gene1182	1.47e-62	206.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1HWTB@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_627283_2	504487.JCM19302_3057	2.97e-33	123.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,1HY3H@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_570642_1	669502.SSDC_00185	1.05e-23	102.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,1KPS7@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_1022802_1	411154.GFO_3594	2.78e-29	108.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,1I418@117743|Flavobacteriia	976|Bacteroidetes	U	Preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_1022802_2	411154.GFO_3593	1.19e-29	112.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,1HZ4X@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_570649_1	1392489.JPOL01000003_gene246	5.93e-52	174.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia,2XHXV@283735|Leeuwenhoekiella	976|Bacteroidetes	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_740044_1	1380600.AUYN01000009_gene2108	7.92e-102	310.0	COG3712@1|root,COG3712@2|Bacteria,4NE6N@976|Bacteroidetes,1HWRF@117743|Flavobacteriia	976|Bacteroidetes	PT	COG3712 Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_740044_2	1121011.AUCB01000028_gene3064	9.81e-26	100.0	COG1595@1|root,COG1595@2|Bacteria,4NQ2T@976|Bacteroidetes,1I399@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_288312_1	929558.SMGD1_0755	6.17e-10	58.5	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2YMRY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1417909_1	1123518.ARWI01000001_gene2255	7.22e-93	275.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,460NB@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_1417909_2	1123517.JOMR01000001_gene658	1.78e-301	822.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,4602C@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_1417909_3	317025.Tcr_0821	2.28e-87	259.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,460R3@72273|Thiotrichales	72273|Thiotrichales	C	NADH dehydrogenase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_1417909_4	317025.Tcr_0822	5.23e-294	804.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,45ZSD@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_1417909_5	90814.KL370891_gene1405	1.22e-67	222.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,45ZUB@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1022819_1	1347342.BN863_34310	1.28e-30	117.0	COG5571@1|root,COG5571@2|Bacteria,4NFAE@976|Bacteroidetes,1HZA2@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
k59_1022819_2	411154.GFO_3230	7.29e-79	242.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1HX0W@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_1247900_1	1380600.AUYN01000009_gene1151	1.9e-112	325.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia	976|Bacteroidetes	S	UvrB UvrC	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
k59_1247900_2	1380600.AUYN01000009_gene1152	2.24e-81	249.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_570663_2	1123518.ARWI01000001_gene680	4.09e-81	250.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RRJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1022829_1	1121931.AUHG01000011_gene2231	7.97e-146	438.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1305526_1	1121931.AUHG01000016_gene1118	1.65e-45	149.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1305526_2	865937.Gilli_3289	1.13e-20	85.1	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2P6Z2@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_118758_2	1379858.N508_00024	3.31e-13	70.9	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03413,ko:K13040	ko02020,ko02030,map02020,map02030	M00506,M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,PAS_9,RelA_SpoT,Response_reg
k59_344285_1	1443665.JACA01000001_gene2928	4.95e-79	240.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2YI22@290174|Aquimarina	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
k59_344285_3	1347342.BN863_580	1.22e-21	85.5	2CD1U@1|root,339YU@2|Bacteria,4NXK7@976|Bacteroidetes,1I6WP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_344285_4	1178825.ALIH01000003_gene2187	4.63e-42	149.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_62495_1	563040.Saut_1124	4.95e-27	100.0	2BT0G@1|root,32N4I@2|Bacteria,1Q3JR@1224|Proteobacteria,432I1@68525|delta/epsilon subdivisions,2YSVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62495_2	929558.SMGD1_2665	9.96e-26	99.4	COG0745@1|root,COG0745@2|Bacteria,1Q4AG@1224|Proteobacteria,42YR3@68525|delta/epsilon subdivisions,2YR20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1078384_1	317025.Tcr_2171	9.37e-55	177.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,460DM@72273|Thiotrichales	72273|Thiotrichales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1078384_2	1168067.JAGP01000001_gene2092	8.5e-43	142.0	2DSZ4@1|root,33I02@2|Bacteria,1NGMX@1224|Proteobacteria,1SGFG@1236|Gammaproteobacteria,461C4@72273|Thiotrichales	72273|Thiotrichales	S	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
k59_1034251_1	1197477.IA57_06150	4.11e-99	306.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1HYTZ@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_582504_1	1380600.AUYN01000010_gene842	9.52e-207	636.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_74671_1	1121931.AUHG01000011_gene1948	1.45e-36	136.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_74671_2	1443665.JACA01000001_gene2655	3.75e-14	72.8	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia,2YHV9@290174|Aquimarina	976|Bacteroidetes	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
k59_1317723_1	1380600.AUYN01000001_gene2685	5.45e-94	295.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1089704_1	90814.KL370891_gene1291	3.45e-140	402.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,45ZRZ@72273|Thiotrichales	72273|Thiotrichales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_74677_1	335543.Sfum_1330	4.01e-71	224.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_130179_1	243924.LT42_16075	1.31e-150	432.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_130179_2	549.BW31_03162	3.19e-19	89.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,3W0J7@53335|Pantoea	1236|Gammaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
k59_300196_1	1168067.JAGP01000001_gene585	1.48e-72	236.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,4625V@72273|Thiotrichales	72273|Thiotrichales	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_16670_1	1121912.AUHD01000011_gene738	2.97e-92	283.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1HWJF@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_470055_1	572480.Arnit_0393	2.7e-85	259.0	COG1344@1|root,COG1344@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_16677_1	323850.Shew_0782	4.08e-69	210.0	COG1522@1|root,COG1522@2|Bacteria,1MWPX@1224|Proteobacteria,1RRPA@1236|Gammaproteobacteria,2QAI4@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	asnC	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016597,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031406,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043177,GO:0043200,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K03718,ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_639343_1	156578.ATW7_07349	1.02e-128	384.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	peptidase, M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_1034280_1	563040.Saut_1583	9.85e-129	385.0	COG1256@1|root,COG1749@1|root,COG1256@2|Bacteria,COG1749@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2YMGR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_808863_1	1356854.N007_09390	4.92e-13	73.2	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,279X9@186823|Alicyclobacillaceae	91061|Bacilli	S	Aldo/keto reductase family	ydhF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1317752_1	1380600.AUYN01000003_gene223	3.36e-91	279.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
k59_1317752_2	1197477.IA57_07810	1.85e-33	126.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_413104_1	411154.GFO_0214	2.86e-37	130.0	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,1I060@117743|Flavobacteriia	976|Bacteroidetes	M	Inorganic polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_413104_2	411154.GFO_0213	7.36e-167	467.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_974865_1	572480.Arnit_0807	8.53e-41	146.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_974865_2	572480.Arnit_0808	1.6e-114	343.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1769272_1	944547.ABLL_2814	1.45e-98	297.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,42PJK@68525|delta/epsilon subdivisions,2YNSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_1769272_2	944546.ABED_2127	7.21e-123	360.0	COG3608@1|root,COG3608@2|Bacteria,1RG3Y@1224|Proteobacteria,42R0N@68525|delta/epsilon subdivisions,2YNXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_808892_1	944547.ABLL_1672	1.04e-40	147.0	29X6U@1|root,30IVZ@2|Bacteria,1P9XM@1224|Proteobacteria	1224|Proteobacteria	S	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
k59_1769273_1	234831.PSM_B0562	3.67e-34	137.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1RZ37@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_244237_2	398720.MED217_07371	3.98e-103	324.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia,2XHXZ@283735|Leeuwenhoekiella	976|Bacteroidetes	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_751431_2	90814.KL370891_gene1873	3.11e-149	426.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,4602A@72273|Thiotrichales	72273|Thiotrichales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_922353_1	526222.Desal_3669	1.51e-13	77.8	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_245944_1	317025.Tcr_0395	3.45e-129	375.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,45ZRA@72273|Thiotrichales	72273|Thiotrichales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_1543319_1	1347342.BN863_9470	4.03e-188	529.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_1543319_2	1286632.P278_06620	0.0	1621.0	COG0457@1|root,COG0457@2|Bacteria,4NIBU@976|Bacteroidetes,1HZ35@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_16,TPR_6,TPR_8
k59_1261654_1	1380600.AUYN01000001_gene2221	4.1e-166	473.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1HWPT@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_189426_1	929558.SMGD1_2715	8e-97	295.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2YRA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_1601789_1	317025.Tcr_1185	1.66e-92	286.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_18298_1	1178825.ALIH01000003_gene2068	3.78e-114	350.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_414771_1	504487.JCM19302_3724	1.47e-89	284.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HY96@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_414771_2	1286632.P278_10250	2.29e-220	619.0	COG3119@1|root,COG3119@2|Bacteria,4NETT@976|Bacteroidetes,1HX4V@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_414771_3	980584.AFPB01000175_gene1793	2.92e-38	136.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1HY0C@117743|Flavobacteriia,406RR@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k59_245986_1	754477.Q7C_1064	2.98e-55	191.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,460MW@72273|Thiotrichales	72273|Thiotrichales	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1374048_1	1506583.JQJY01000004_gene2924	1.92e-52	181.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,4NE6R@976|Bacteroidetes,1HWYU@117743|Flavobacteriia,2NT90@237|Flavobacterium	976|Bacteroidetes	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k59_1374048_2	1392490.JHZX01000001_gene392	1.2e-50	162.0	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,1I2S1@117743|Flavobacteriia	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
k59_357394_1	765952.PUV_15760	2.76e-68	238.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569,DUF3857,Transglut_core
k59_131830_1	1392490.JHZX01000001_gene3288	8.68e-50	164.0	2AQR4@1|root,31FYV@2|Bacteria,4NQYS@976|Bacteroidetes,1I3DS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131830_2	1380600.AUYN01000009_gene1531	5.03e-107	310.0	COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,1HXWP@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_976193_1	983544.Lacal_1361	4.14e-138	417.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1657844_1	90814.KL370891_gene1495	4.36e-34	119.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
k59_1657844_2	1123514.KB905899_gene578	7.34e-65	208.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,460IH@72273|Thiotrichales	72273|Thiotrichales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_810777_1	1121931.AUHG01000010_gene818	3.37e-134	407.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_414804_1	572480.Arnit_1917	9.99e-154	456.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2YMV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1261728_1	945713.IALB_1856	7.72e-96	295.0	COG0504@1|root,COG0504@2|Bacteria	2|Bacteria	F	CTP synthase activity	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377	CTP_synth_N,GATase
k59_1714426_1	1123518.ARWI01000001_gene563	4.48e-05	53.1	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,45ZQF@72273|Thiotrichales	72273|Thiotrichales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_189495_1	1121931.AUHG01000015_gene1181	2.74e-107	329.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,4NJDM@976|Bacteroidetes,1I8IH@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
k59_414813_1	1237149.C900_03446	7.13e-48	172.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,47KGC@768503|Cytophagia	976|Bacteroidetes	L	PFAM DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
k59_1147972_1	1537917.JU82_05960	1.75e-12	71.6	COG0642@1|root,COG5000@1|root,COG0642@2|Bacteria,COG5000@2|Bacteria,1N5IQ@1224|Proteobacteria,42N7Z@68525|delta/epsilon subdivisions,2YN64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1147972_2	1150621.SMUL_2189	6.79e-86	258.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42QPB@68525|delta/epsilon subdivisions,2YNVC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Chemotaxis protein CheY	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_866574_1	1123518.ARWI01000001_gene1463	2.71e-264	745.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_866574_2	317025.Tcr_0013	2.39e-117	341.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,461IU@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k59_641180_1	223283.PSPTO_0532	1.46e-07	50.4	2DSAS@1|root,33F9P@2|Bacteria,1MZNZ@1224|Proteobacteria,1SSMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1374105_1	641526.ADIWIN_2789	4.22e-48	161.0	COG1670@1|root,COG1670@2|Bacteria,4NMQQ@976|Bacteroidetes,1I180@117743|Flavobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k59_1374105_2	746697.Aeqsu_0598	6.21e-212	596.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1200283_1	411154.GFO_0618	1.53e-124	375.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1091485_1	653733.Selin_1394	3.54e-73	227.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB-7	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_1091485_2	1121918.ARWE01000001_gene3086	6.78e-14	70.9	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,43T69@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Nitrate_red_gam
k59_976232_1	572480.Arnit_2512	1.82e-144	418.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2YMQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_976233_1	1089548.KI783301_gene124	9.78e-09	56.6	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,3WFA2@539002|Bacillales incertae sedis	91061|Bacilli	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,DUF1533,F5_F8_type_C,Glyco_hydro_16,SLH
k59_976233_2	1144313.PMI10_04185	1.62e-40	140.0	COG4845@1|root,COG4845@2|Bacteria,4NPDG@976|Bacteroidetes,1I20U@117743|Flavobacteriia,2NUA5@237|Flavobacterium	976|Bacteroidetes	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
k59_1036118_1	272943.RSP_3359	9.32e-74	232.0	COG3500@1|root,COG3500@2|Bacteria,1MXT8@1224|Proteobacteria,2U5ET@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	R COG3500 Phage protein D	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	Phage_GPD
k59_753101_1	1200567.JNKD01000037_gene457	1.2e-16	85.9	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1Y3R6@135624|Aeromonadales	135624|Aeromonadales	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
k59_527733_1	1137281.D778_02841	2.77e-58	182.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1HYHU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_527733_2	1392490.JHZX01000001_gene1511	5.88e-53	172.0	2CJ0K@1|root,32S8Y@2|Bacteria,4NU98@976|Bacteroidetes,1I2IY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
k59_527733_3	1041826.FCOL_09260	6.99e-10	59.3	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia,2NSCD@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_866616_2	326298.Suden_0020	2.7e-46	162.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2YRTC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1431017_2	1286093.C266_02556	2.3e-19	90.5	28JV9@1|root,2Z9K8@2|Bacteria,1MVTX@1224|Proteobacteria,2VP25@28216|Betaproteobacteria,1K37M@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1319661_1	572480.Arnit_1883	6.75e-126	361.0	COG0847@1|root,COG0847@2|Bacteria,1PDD1@1224|Proteobacteria,42MUX@68525|delta/epsilon subdivisions,2YNB6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0847 DNA polymerase III epsilon subunit and related 3'-5'	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1319661_2	983328.AFGH01000033_gene809	5.85e-06	49.7	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2YNF8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flgR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_357518_1	1004149.AFOE01000055_gene168	4.05e-86	280.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_131936_1	1565129.JSFF01000014_gene407	5.16e-09	56.6	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RR3D@1236|Gammaproteobacteria,2Q8Y1@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_131936_2	94122.Shewana3_2569	1.88e-43	141.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2QCJ0@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_357522_1	1131269.AQVV01000009_gene1148	3.25e-14	70.1	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
k59_357522_2	1232410.KI421422_gene2012	6.17e-64	202.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,43SD4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_1657944_1	1191523.MROS_2107	2.27e-82	271.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k59_1488364_1	1347342.BN863_20510	1.99e-39	141.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1HXUW@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_1488364_2	1380600.AUYN01000001_gene2377	2.55e-306	835.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
k59_976271_1	62928.azo2884	2.06e-91	273.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,2KUK6@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1261846_1	411154.GFO_2271	7.43e-109	335.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1HXTQ@117743|Flavobacteriia	976|Bacteroidetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1543506_1	411154.GFO_1960	6.17e-56	194.0	COG1352@1|root,COG2201@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HWYQ@117743|Flavobacteriia	976|Bacteroidetes	T	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
k59_866671_1	1056512.D515_01233	4.99e-35	133.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria,1XX1Z@135623|Vibrionales	135623|Vibrionales	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_18453_1	1565129.JSFF01000004_gene3062	5.35e-66	216.0	COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,1RNFC@1236|Gammaproteobacteria,2Q8UC@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
k59_302247_1	1380600.AUYN01000009_gene967	1.96e-114	367.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_131990_1	323850.Shew_2440	5.65e-14	71.6	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q9QR@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1385754_1	40373.F991_01887	1.93e-55	194.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,3NJFY@468|Moraxellaceae	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164	PBP1_TM,Transgly,Transpeptidase,UB2H
k59_483880_1	1123518.ARWI01000001_gene2130	3.34e-181	516.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,45ZXD@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1,Acetyltransf_7
k59_1726117_1	572480.Arnit_1552	7.31e-138	404.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2YMAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1726117_2	572480.Arnit_1553	8.1e-54	179.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2YN0D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	MiaB-like tRNA modifying enzyme	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
k59_595620_1	1380600.AUYN01000006_gene365	8.02e-251	691.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_595620_2	1538644.KO02_02015	5.5e-55	189.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,1IQX6@117747|Sphingobacteriia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
k59_1442492_1	326298.Suden_0358	1.3e-104	307.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k59_1442493_1	1123367.C666_09865	6.55e-46	153.0	COG1502@1|root,COG1502@2|Bacteria,1RG6H@1224|Proteobacteria,2VRJW@28216|Betaproteobacteria,2KWF8@206389|Rhodocyclales	206389|Rhodocyclales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k59_1442493_2	62928.azo3120	8.95e-10	60.8	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,2KU8B@206389|Rhodocyclales	206389|Rhodocyclales	M	mechanosensitive	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM,MscS_porin
k59_1555201_1	1120966.AUBU01000003_gene1656	7.69e-58	190.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,47K6J@768503|Cytophagia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1208133_1	425104.Ssed_4298	2.6e-37	135.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,2QAR6@267890|Shewanellaceae	1236|Gammaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1208133_2	458817.Shal_4115	1.82e-80	240.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,2QBMD@267890|Shewanellaceae	1236|Gammaproteobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_201384_1	1123518.ARWI01000001_gene1580	1.4e-75	234.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1RR6P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Flp pilus assembly protein TadC	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_711803_1	317025.Tcr_1746	1e-48	166.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,460N2@72273|Thiotrichales	72273|Thiotrichales	S	Permease YjgP YjgQ	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_711803_2	1123518.ARWI01000001_gene838	8.98e-145	421.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,460RT@72273|Thiotrichales	72273|Thiotrichales	S	Permease YjgP YjgQ	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_1385796_1	572480.Arnit_2342	2.78e-95	290.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1385796_2	572480.Arnit_2341	9.97e-20	81.6	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2YPWF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_539644_1	1121931.AUHG01000012_gene2599	1.97e-116	343.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes,1I2DH@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_1160237_1	1123514.KB905900_gene2130	7.27e-130	396.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,4603Y@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1385806_1	411154.GFO_2064	4.98e-06	47.4	COG2197@1|root,COG2197@2|Bacteria,4NKCC@976|Bacteroidetes,1I0ID@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1385806_2	411154.GFO_2063	2e-08	58.9	2DR29@1|root,339VD@2|Bacteria,4NZEP@976|Bacteroidetes,1I852@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31454_2	338963.Pcar_1822	1.17e-30	124.0	COG4643@1|root,COG4643@2|Bacteria,1QZ5M@1224|Proteobacteria	1224|Proteobacteria	P	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1334078_1	411154.GFO_3156	2.14e-108	323.0	COG1249@1|root,COG1249@2|Bacteria,4NFUB@976|Bacteroidetes,1HXVG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1275443_1	392500.Swoo_3188	4.84e-117	347.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,2QAIJ@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase M17, leucyl aminopeptidase domain protein	pepA2	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
k59_1616456_1	1211813.CAPH01000006_gene1653	1.11e-19	87.4	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,2FNKW@200643|Bacteroidia,22UAV@171550|Rikenellaceae	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1616456_2	1196028.ALEF01000081_gene3414	0.000162	46.6	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,4C4WU@84406|Virgibacillus	91061|Bacilli	KT	Phosphoserine phosphatase RsbU, N-terminal domain	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	RsbU_N,SpoIIE
k59_1162188_1	929558.SMGD1_0040	1.04e-119	349.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2YP35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	hemK	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
k59_1275449_1	1123518.ARWI01000001_gene1048	2.74e-136	388.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,46090@72273|Thiotrichales	72273|Thiotrichales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_1275449_2	1123518.ARWI01000001_gene1049	5.85e-88	259.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,460I0@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_1275449_3	90813.JQMT01000001_gene202	7.99e-112	322.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,460GQ@72273|Thiotrichales	72273|Thiotrichales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_1275449_4	1123514.KB905899_gene1833	3.25e-56	177.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1SB9R@1236|Gammaproteobacteria,463R6@72273|Thiotrichales	72273|Thiotrichales	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	-	-	-	-	-	-	-	-	-	SecE
k59_145455_1	1298863.AUEP01000013_gene4081	0.000721	47.8	COG2114@1|root,COG2771@1|root,COG3903@1|root,COG2114@2|Bacteria,COG2771@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DP21@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,GerE,Guanylate_cyc,NB-ARC,Trans_reg_C
k59_935473_1	1385935.N836_20470	1.36e-78	248.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1H8RN@1150|Oscillatoriales	1117|Cyanobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
k59_1105294_1	317025.Tcr_1235	5.39e-48	159.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,1S5WS@1236|Gammaproteobacteria,461D6@72273|Thiotrichales	72273|Thiotrichales	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_1105294_2	1123518.ARWI01000001_gene175	1.47e-17	77.0	COG1974@1|root,COG1974@2|Bacteria,1RKEA@1224|Proteobacteria,1S84R@1236|Gammaproteobacteria,463NC@72273|Thiotrichales	72273|Thiotrichales	L	Peptidase S24-like	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
k59_825533_1	1347342.BN863_5130	2.16e-23	107.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_825533_2	1380600.AUYN01000009_gene1771	6.86e-202	563.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HXVU@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1671712_1	709032.Sulku_2152	1.66e-29	108.0	COG1544@1|root,COG1544@2|Bacteria,1QNAY@1224|Proteobacteria,430WG@68525|delta/epsilon subdivisions,2YS0N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_1671712_2	929558.SMGD1_0839	5.09e-58	189.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2YMK7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_1105314_1	1121007.AUML01000019_gene749	0.00017	42.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia,2YHK5@290174|Aquimarina	976|Bacteroidetes	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_1105314_2	1137281.D778_02059	1.77e-66	207.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_935493_1	944547.ABLL_0601	8.52e-132	387.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YMGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_1334134_1	411154.GFO_0194	6.1e-19	82.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
k59_1334134_2	411154.GFO_0193	3.9e-118	342.0	COG1999@1|root,COG1999@2|Bacteria,4NGHC@976|Bacteroidetes,1HXW6@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	ypmQ	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1334134_3	1121931.AUHG01000010_gene845	3.88e-67	208.0	29WBK@1|root,30HX5@2|Bacteria,4NMWM@976|Bacteroidetes,1I1KG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1502738_1	572480.Arnit_0100	1.39e-53	179.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OmpA
k59_1728065_1	1123514.KB905899_gene1503	6.53e-220	631.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,45ZW4@72273|Thiotrichales	72273|Thiotrichales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1444334_1	1353537.TP2_15445	2.13e-134	388.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2XP6F@285107|Thioclava	28211|Alphaproteobacteria	E	the ABC transporter	-	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
k59_988569_1	1380600.AUYN01000001_gene2254	1.25e-224	627.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_988569_2	1392490.JHZX01000001_gene3442	8.55e-13	68.2	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1HWK9@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_31526_1	1122599.AUGR01000027_gene1273	1.09e-25	107.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XIWW@135619|Oceanospirillales	135619|Oceanospirillales	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k59_371271_1	563040.Saut_1407	2.27e-147	426.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2YN93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	anthranilate synthase component	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1282	Anth_synt_I_N,Chorismate_bind
k59_1502757_2	273121.WS0212	1.49e-14	75.5	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMJS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,NIT,Response_reg
k59_260254_1	1380600.AUYN01000003_gene108	5.76e-102	297.0	COG1595@1|root,COG1595@2|Bacteria,4NN0Y@976|Bacteroidetes,1I0F7@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_371283_1	1565129.JSFF01000025_gene1320	1.04e-108	322.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,1RPY4@1236|Gammaproteobacteria,2Q8T8@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM glycosyl transferase group 1	rfaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_541550_1	1121931.AUHG01000011_gene1899	2.01e-66	208.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,1HX82@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_260274_1	1380600.AUYN01000009_gene1967	6.5e-99	300.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1HZGE@117743|Flavobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
k59_1616562_1	411154.GFO_1749	7.88e-26	103.0	COG0454@1|root,COG0454@2|Bacteria,4NM1Z@976|Bacteroidetes	976|Bacteroidetes	K	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
k59_1616562_2	1121931.AUHG01000017_gene1553	1.06e-173	486.0	COG0101@1|root,COG0101@2|Bacteria,4NG3N@976|Bacteroidetes,1HX0T@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_1616562_3	1121931.AUHG01000017_gene1554	3.91e-18	83.2	COG0514@1|root,COG0514@2|Bacteria,4NG10@976|Bacteroidetes,1HXWC@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ3	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_1444385_1	572480.Arnit_1345	2.1e-109	335.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2YR4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Hydrolase_4
k59_1785322_1	1353528.DT23_01345	4.66e-69	209.0	COG5416@1|root,COG5416@2|Bacteria,1Q7UY@1224|Proteobacteria,2V74A@28211|Alphaproteobacteria,2XNIK@285107|Thioclava	28211|Alphaproteobacteria	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
k59_1785322_2	391624.OIHEL45_00990	5.17e-16	71.2	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_597396_1	929558.SMGD1_0695	7.33e-44	166.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2YTKD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HATPase_c,PAS_9
k59_541583_1	929558.SMGD1_0425	5.3e-37	135.0	28NUA@1|root,2ZBSQ@2|Bacteria,1QE31@1224|Proteobacteria,42Z7U@68525|delta/epsilon subdivisions,2YR9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_371311_1	1120951.AUBG01000013_gene2686	1.21e-87	288.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,1IMNF@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
k59_371311_2	1178825.ALIH01000004_gene2900	6.77e-114	342.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1105398_1	572480.Arnit_1321	1.85e-26	99.0	COG0662@1|root,COG0662@2|Bacteria,1QVWV@1224|Proteobacteria	1224|Proteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_1105398_2	572480.Arnit_1320	2.43e-113	339.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,43CSA@68525|delta/epsilon subdivisions,2YNV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1502820_1	411154.GFO_3252	8.17e-98	293.0	COG0272@1|root,COG0758@1|root,COG0272@2|Bacteria,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1HXG0@117743|Flavobacteriia	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k59_1785330_1	1380600.AUYN01000001_gene2798	1.41e-43	160.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_1785330_2	1131812.JQMS01000001_gene2861	1.84e-13	68.9	2EMEB@1|root,33F36@2|Bacteria,4NY31@976|Bacteroidetes,1I6MM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1785330_3	1380600.AUYN01000009_gene1102	0.0	1094.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_1785330_4	1380600.AUYN01000001_gene2617	4.04e-186	527.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia	976|Bacteroidetes	G	Transporter	gluP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_31591_1	1172190.M947_10605	5.7e-107	328.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_145586_1	929558.SMGD1_0976	1.2e-102	298.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2YN2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_145586_2	563040.Saut_0228	2.48e-38	127.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2YQIN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_145586_3	929558.SMGD1_0975	3.12e-85	251.0	COG0096@1|root,COG0096@2|Bacteria,1N3R7@1224|Proteobacteria,43AC0@68525|delta/epsilon subdivisions,2YP6G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_145586_4	563040.Saut_0230	6.27e-56	177.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2YMUG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_1275601_1	563040.Saut_0653	1.59e-62	194.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,42V0H@68525|delta/epsilon subdivisions,2YQ7R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1444444_1	1507.HMPREF0262_02548	1.64e-13	69.7	COG0258@1|root,COG0258@2|Bacteria,1VRDB@1239|Firmicutes,24EYZ@186801|Clostridia,36S9S@31979|Clostridiaceae	186801|Clostridia	L	5'-3' exonuclease, SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
k59_988702_1	1353276.JADR01000005_gene2548	9.31e-53	182.0	COG3307@1|root,COG3307@2|Bacteria,4NGIS@976|Bacteroidetes,1HYGB@117743|Flavobacteriia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_988702_2	745718.JADT01000005_gene88	1.06e-94	289.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,1HZQ0@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_316200_1	1347342.BN863_2820	1.68e-155	461.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_935651_1	929558.SMGD1_1574	1.2e-72	240.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_90378_1	28072.Nos7524_1430	1.4e-07	58.5	COG1106@1|root,COG1106@2|Bacteria,1G3YN@1117|Cyanobacteria,1HPU7@1161|Nostocales	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
k59_145650_1	504472.Slin_4238	1.74e-54	193.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1557316_1	543728.Vapar_5409	3.78e-23	100.0	COG0583@1|root,COG0583@2|Bacteria,1MX2F@1224|Proteobacteria,2VH84@28216|Betaproteobacteria,4AJ3A@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1557319_2	1172190.M947_08265	3.42e-61	190.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2YNYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_1162432_2	1123517.JOMR01000001_gene1390	3.33e-81	254.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,1RNU6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_1401423_2	563040.Saut_1406	8.51e-31	114.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,42W4N@68525|delta/epsilon subdivisions	1224|Proteobacteria	D	Sporulation related domain	ftsN	-	-	ko:K03591,ko:K03749	-	-	-	-	ko00000,ko03036	-	-	-	SPOR
k59_1179350_2	929558.SMGD1_2726	2.21e-105	312.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2YME5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_1688836_1	1353528.DT23_03000	3.81e-47	167.0	28IN1@1|root,2Z8NH@2|Bacteria,1MWM2@1224|Proteobacteria,2TUUR@28211|Alphaproteobacteria,2XKT0@285107|Thioclava	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1688836_2	1185766.DL1_13855	4.17e-18	80.5	COG1564@1|root,COG1564@2|Bacteria,1RE29@1224|Proteobacteria,2U7FB@28211|Alphaproteobacteria,2XNAM@285107|Thioclava	28211|Alphaproteobacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
k59_1351477_1	323850.Shew_0258	5.51e-16	75.9	297BA@1|root,2ZUIX@2|Bacteria,1P5Z6@1224|Proteobacteria,1SVCI@1236|Gammaproteobacteria,2QAEJ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_107663_1	1250278.JQNQ01000001_gene3237	1.43e-38	145.0	2DUH4@1|root,33QM8@2|Bacteria,4NPKV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
k59_1520266_1	1392489.JPOL01000002_gene1287	1.08e-37	142.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1802579_1	1121931.AUHG01000010_gene790	4.7e-69	218.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1HWUX@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_949655_1	326298.Suden_1123	2.48e-38	139.0	COG1261@1|root,COG1261@2|Bacteria,1Q3ZV@1224|Proteobacteria,42Y1K@68525|delta/epsilon subdivisions,2YQRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chaperone for flagella basal body P-ring formation	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_1225117_1	1286632.P278_00790	1.4e-45	150.0	COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes,1I4CE@117743|Flavobacteriia	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
k59_896386_1	1121007.AUML01000032_gene2755	2.41e-68	226.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia,2YHQ2@290174|Aquimarina	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_896386_2	1443665.JACA01000005_gene326	1.69e-41	146.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1HXMQ@117743|Flavobacteriia,2YH8Z@290174|Aquimarina	976|Bacteroidetes	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_161806_1	926562.Oweho_3073	1.38e-63	197.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1I20H@117743|Flavobacteriia,2PAXW@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_161806_2	1035193.HMPREF9073_02182	4.15e-12	63.5	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1HWK7@117743|Flavobacteriia,1EQPC@1016|Capnocytophaga	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_1005563_2	700598.Niako_0776	7.01e-38	144.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IPB0@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_445114_1	391587.KAOT1_01190	1.51e-129	378.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_445114_2	1380600.AUYN01000009_gene1664	0.0	931.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_556828_1	797515.HMPREF9103_02863	2.4e-63	206.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae	91061|Bacilli	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_1745843_2	443143.GM18_0419	6.27e-49	159.0	2CCSR@1|root,32RWC@2|Bacteria,1MZFP@1224|Proteobacteria,42U6B@68525|delta/epsilon subdivisions,2WWR7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_274964_1	62928.azo0920	3.9e-82	248.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2VQMP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	dctQ	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
k59_220410_1	1395571.TMS3_0120425	4.27e-96	291.0	COG3677@1|root,COG3677@2|Bacteria,1R999@1224|Proteobacteria,1S1Q7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,HTH_23,Zn_Tnp_IS1595
k59_1573454_1	1172190.M947_09830	3.24e-114	352.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1005602_2	387093.SUN_1018	1.68e-49	158.0	COG2161@1|root,COG2161@2|Bacteria,1N8QY@1224|Proteobacteria,42WS8@68525|delta/epsilon subdivisions,2YQ0I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_161859_1	572480.Arnit_1555	8.47e-22	89.0	COG2267@1|root,COG2267@2|Bacteria,1Q0VR@1224|Proteobacteria,42SJB@68525|delta/epsilon subdivisions,2YPM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_161859_2	572480.Arnit_1554	1.81e-73	234.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42NK1@68525|delta/epsilon subdivisions,2YMHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the AAA ATPase family	ftsH1	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k59_1745879_1	1227352.C173_14970	1.25e-31	125.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,26QEQ@186822|Paenibacillaceae	91061|Bacilli	G	COG0366 Glycosidases	malL	-	3.2.1.10	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01718,R01791,R06199	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_445169_1	1172190.M947_04880	1.81e-52	169.0	2BQTZ@1|root,32JQR@2|Bacteria,1Q2FB@1224|Proteobacteria,431HI@68525|delta/epsilon subdivisions,2YS7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_445169_3	326298.Suden_1511	1.63e-14	73.2	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42RQ2@68525|delta/epsilon subdivisions,2YP69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GGDEF
k59_1403671_1	323850.Shew_2882	1.36e-109	316.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,2QAB8@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300	LuxS
k59_896480_1	1122225.AULQ01000004_gene2079	2.11e-67	207.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1I1X6@117743|Flavobacteriia	976|Bacteroidetes	S	YqeY-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k59_1292718_1	326298.Suden_0003	3.61e-130	390.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2YMUW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1351657_1	1191523.MROS_0931	3.15e-25	107.0	COG0497@1|root,COG0497@2|Bacteria	2|Bacteria	L	DNA recombination	recN	-	-	ko:K03546,ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_672723_1	1123518.ARWI01000001_gene400	5.84e-15	73.9	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_672723_2	90814.KL370891_gene899	3.07e-72	223.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_161931_1	458817.Shal_3894	2.5e-86	265.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,2Q9Q1@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_1745942_1	1165841.SULAR_04252	7.72e-138	413.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2YNBY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_1745942_2	221288.JH992901_gene1889	1.5e-13	73.2	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GD97@1117|Cyanobacteria	1117|Cyanobacteria	T	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,Pkinase
k59_1179547_1	929558.SMGD1_0016	3.2e-11	62.8	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,42KZV@68525|delta/epsilon subdivisions,2YM8J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	flgS	-	2.7.13.3	ko:K02482,ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1179547_2	326298.Suden_0913	8.79e-88	270.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2YRFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k59_1403721_1	1565129.JSFF01000001_gene919	8.11e-113	332.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,2Q9H6@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily	rlmM	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_839370_1	90814.KL370891_gene251	6.21e-22	89.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,460ID@72273|Thiotrichales	72273|Thiotrichales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_839370_2	90814.KL370891_gene250	6.35e-62	191.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,460WC@72273|Thiotrichales	72273|Thiotrichales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_839370_3	317025.Tcr_0310	8.17e-89	264.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,460IG@72273|Thiotrichales	72273|Thiotrichales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_839370_4	1123518.ARWI01000001_gene1024	1.22e-77	232.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,460S8@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_839370_5	317025.Tcr_0308	7.48e-58	180.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,460WT@72273|Thiotrichales	72273|Thiotrichales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_839370_6	90814.KL370891_gene246	7.63e-111	320.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,460DF@72273|Thiotrichales	72273|Thiotrichales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_839370_7	90814.KL370891_gene245	3.46e-12	61.6	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,460ZF@72273|Thiotrichales	72273|Thiotrichales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_1351685_1	90814.KL370891_gene1088	9.89e-90	284.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4601S@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1225295_1	717772.THIAE_00905	2.46e-62	199.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,1RNEH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	(ABC) transporter	nrtC	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
k59_1225295_2	317025.Tcr_0040	5.9e-81	242.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,460XE@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
k59_1225295_3	1168067.JAGP01000001_gene2148	1.99e-18	82.8	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RQNH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese-like domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_388516_2	1168067.JAGP01000001_gene315	7.99e-56	194.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1460676_1	572480.Arnit_0491	3.76e-103	320.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_47651_1	1123326.JFBL01000002_gene1587	4.05e-27	115.0	COG3437@1|root,COG4564@1|root,COG3437@2|Bacteria,COG4564@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2YTKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_9,Response_reg
k59_1460682_1	323850.Shew_3487	1.58e-115	333.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,2Q8JK@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186	Pribosyltran
k59_556961_1	411154.GFO_0600	4.36e-190	535.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_333540_1	1527519.A0A076G6R9_9CAUD	2.19e-09	58.9	4QAWG@10239|Viruses,4QPII@28883|Caudovirales,4QI76@10662|Myoviridae	10662|Myoviridae	S	DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_333540_2	979525.F1D180_9CAUD	2.81e-36	142.0	4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses  no RNA stage,4QPEF@28883|Caudovirales,4QI32@10662|Myoviridae	10662|Myoviridae	S	DNA polymerase family A	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1629270_1	1268240.ATFI01000009_gene1612	1.46e-16	74.3	COG3943@1|root,COG3943@2|Bacteria,4NEGN@976|Bacteroidetes,2FQB8@200643|Bacteroidia	976|Bacteroidetes	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
k59_1629270_2	1249480.B649_00895	8.25e-131	378.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,42NYC@68525|delta/epsilon subdivisions,2YN8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
k59_1520496_1	497321.C664_19281	2e-58	193.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,2KUCZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_1065304_2	1123518.ARWI01000001_gene713	6.91e-102	308.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,45ZX7@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_1629273_1	1123518.ARWI01000001_gene1748	3.26e-125	366.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZXJ@72273|Thiotrichales	72273|Thiotrichales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1629273_2	90814.KL370891_gene1890	1.25e-121	347.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,460E0@72273|Thiotrichales	72273|Thiotrichales	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_839393_1	563040.Saut_0528	3.71e-112	337.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,42NCG@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_839393_2	929558.SMGD1_1783	3.16e-114	338.0	COG0642@1|root,COG0642@2|Bacteria,1N5IQ@1224|Proteobacteria,42M9P@68525|delta/epsilon subdivisions,2YN0U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cprS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_784707_1	1123518.ARWI01000001_gene1162	2.02e-101	311.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,4604M@72273|Thiotrichales	72273|Thiotrichales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_220545_2	159087.Daro_3458	1.88e-121	362.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KVRV@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
k59_220545_3	864069.MicloDRAFT_00022770	8.42e-18	89.4	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,1JSTD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9
k59_220555_2	1265507.KB899640_gene129	1.18e-05	46.6	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,1SFR6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_1005757_1	349521.HCH_02621	4.38e-51	169.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,1XHFV@135619|Oceanospirillales	135619|Oceanospirillales	S	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_672814_1	326298.Suden_1496	5.6e-82	266.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42SS2@68525|delta/epsilon subdivisions,2YRAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_1460758_1	929558.SMGD1_1476	3.1e-61	211.0	COG1413@1|root,COG1413@2|Bacteria,1QZXI@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1460770_1	694427.Palpr_0581	8.17e-14	76.3	COG1629@1|root,COG2373@1|root,COG1629@2|Bacteria,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,2FPX1@200643|Bacteroidia,22Z3N@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47741_1	1123518.ARWI01000001_gene888	8.94e-133	390.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,45ZQG@72273|Thiotrichales	72273|Thiotrichales	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_784773_2	443152.MDG893_20544	1.1e-19	95.9	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Collar,DUF859,Laminin_G_3,Phage_fiber_2
k59_388633_1	572480.Arnit_1837	1.05e-24	101.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2YR2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_1131347_1	929558.SMGD1_0934	2.33e-45	158.0	COG0667@1|root,COG0667@2|Bacteria,1RHYD@1224|Proteobacteria,42SEU@68525|delta/epsilon subdivisions,2YT8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_961751_1	1336803.PHEL49_1016	2.18e-55	180.0	COG1073@1|root,COG1073@2|Bacteria,4NH47@976|Bacteroidetes,1HYN1@117743|Flavobacteriia,3VW2G@52959|Polaribacter	976|Bacteroidetes	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9
k59_961751_2	1123234.AUKI01000002_gene1798	1.03e-24	103.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1243821_1	388413.ALPR1_20508	1.21e-143	419.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1243821_2	1237149.C900_04604	2.64e-07	50.4	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_1583142_1	411154.GFO_0771	1.9e-68	217.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1HX4E@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1583142_2	411154.GFO_0772	1.31e-19	88.6	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
k59_397014_1	411154.GFO_2709	8.16e-51	166.0	2DVK3@1|root,32UZN@2|Bacteria,4NUAC@976|Bacteroidetes,1I42R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_397014_2	1121931.AUHG01000011_gene1806	2.36e-93	276.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HXRV@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_792298_1	1268303.RHODMAR_2888	2.35e-26	103.0	COG3663@1|root,COG3663@2|Bacteria,2IGMS@201174|Actinobacteria,4G2PP@85025|Nocardiaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	nnrE	-	-	-	-	-	-	-	-	-	-	-	UDG,YjeF_N
k59_792298_2	1499967.BAYZ01000137_gene105	1.2e-29	126.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,2NPJ3@2323|unclassified Bacteria	2|Bacteria	T	diguanylate cyclase	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_792298_3	1168067.JAGP01000001_gene1142	5.38e-41	141.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,1SCDT@1236|Gammaproteobacteria,463EB@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_566376_1	1121931.AUHG01000017_gene1476	3.72e-92	281.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
k59_566376_2	1121931.AUHG01000017_gene1477	7.49e-148	419.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1131366_1	629742.STAHO0001_0775	4.76e-07	49.7	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,4GYXP@90964|Staphylococcaceae	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_1131366_2	1123518.ARWI01000001_gene2148	5.48e-61	188.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,46136@72273|Thiotrichales	72273|Thiotrichales	S	Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_1131366_3	1123518.ARWI01000001_gene2147	9.88e-76	228.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,460QP@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_1131366_4	90814.KL370891_gene1509	3.85e-112	328.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4608T@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_340215_1	411154.GFO_0787	3.18e-64	199.0	COG0544@1|root,COG0544@2|Bacteria,4PMNC@976|Bacteroidetes,1IJVR@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_340215_2	1121931.AUHG01000016_gene1058	5.14e-64	205.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_1639772_1	292415.Tbd_1795	1.49e-26	107.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,1KTHB@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_1074388_1	929558.SMGD1_2766	1.17e-28	118.0	COG2984@1|root,COG2984@2|Bacteria,1PGQI@1224|Proteobacteria,43496@68525|delta/epsilon subdivisions,2YRIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_283947_2	563040.Saut_1823	5.64e-62	207.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_397043_2	1380600.AUYN01000009_gene1783	2.64e-77	233.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
k59_792318_2	392500.Swoo_3060	1.61e-100	325.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,2Q8KA@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM SMC domain protein	sbcC	GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576,GO:1990238	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
k59_961810_1	641526.ADIWIN_1174	1.27e-209	600.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31
k59_1074396_1	1121931.AUHG01000019_gene3058	5.03e-91	280.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,1HXSD@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1074396_2	869213.JCM21142_52293	5.42e-42	141.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,47R9R@768503|Cytophagia	976|Bacteroidetes	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_171132_1	1565129.JSFF01000006_gene2493	1.9e-75	233.0	COG3766@1|root,COG3766@2|Bacteria,1Q8XV@1224|Proteobacteria,1T1F5@1236|Gammaproteobacteria,2Q94J@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
k59_340246_1	1484460.JSWG01000015_gene916	1.78e-80	250.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia	976|Bacteroidetes	P	COG3420 Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
k59_1243872_1	688270.Celal_4276	6.08e-95	285.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia,1FA2B@104264|Cellulophaga	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_1243872_2	1178825.ALIH01000002_gene866	1.19e-206	576.0	COG0516@1|root,COG0516@2|Bacteria,4NHGE@976|Bacteroidetes,1HX35@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	-	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
k59_453552_1	1347342.BN863_23490	4.14e-219	617.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,1HXD0@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_114676_1	1123514.KB905899_gene1119	1.24e-177	509.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_509521_1	203122.Sde_2999	1.39e-33	129.0	COG2207@1|root,COG2207@2|Bacteria,1N8IV@1224|Proteobacteria,1RNPB@1236|Gammaproteobacteria,465F1@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_283985_1	317025.Tcr_1495	1.49e-117	343.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,461SY@72273|Thiotrichales	72273|Thiotrichales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_114679_1	1565129.JSFF01000003_gene2165	2.85e-43	157.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,2QAH6@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfC	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
k59_227621_1	1353276.JADR01000008_gene840	1.02e-11	63.2	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia	976|Bacteroidetes	S	UvrB UvrC	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
k59_227621_2	391598.FBBAL38_03680	5.04e-240	666.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes,1HYMV@117743|Flavobacteriia	976|Bacteroidetes	G	nucleoside permease	nupG	-	-	ko:K03289,ko:K11537	-	-	-	-	ko00000,ko02000	2.A.1.10.1,2.A.1.10.2	-	-	Nuc_H_symport
k59_1752739_1	1242864.D187_000199	2.38e-79	256.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
k59_1018453_1	411154.GFO_2706	3.49e-120	353.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_961843_1	1123514.KB905899_gene470	7.87e-199	599.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,4609U@72273|Thiotrichales	72273|Thiotrichales	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_340270_1	1137281.D778_01157	7.26e-31	117.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,1HY21@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX amino terminal protease family	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_340270_2	1178825.ALIH01000006_gene1410	2.36e-51	171.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1HY3V@117743|Flavobacteriia	976|Bacteroidetes	M	mandelate racemase	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
k59_679568_1	1123518.ARWI01000001_gene1903	3.99e-106	311.0	COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,1T1GC@1236|Gammaproteobacteria,460VF@72273|Thiotrichales	72273|Thiotrichales	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_397099_1	358220.C380_00290	3.39e-84	282.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF,GAF_2,GGDEF,NMT1,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9
k59_1413880_1	1122225.AULQ01000010_gene181	2.21e-137	397.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1413880_2	504487.JCM19302_1405	7.77e-68	214.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_735985_1	317025.Tcr_1791	1.53e-111	324.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,1RR1E@1236|Gammaproteobacteria,461GT@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_735985_2	317025.Tcr_1790	3.33e-71	221.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,1RN5H@1236|Gammaproteobacteria,462BY@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_848478_1	1392490.JHZX01000001_gene1442	4.4e-78	255.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia	976|Bacteroidetes	U	phosphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_566477_1	1178825.ALIH01000019_gene1222	3.67e-64	203.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_566477_2	991.IW20_02110	3.24e-35	132.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia,2NUTT@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_735994_1	929558.SMGD1_1570	4.6e-106	330.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2YMJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_397132_1	563040.Saut_1120	2.86e-104	307.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2YMMW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_397132_2	563040.Saut_1121	3.75e-05	44.3	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2YMM0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	oxidoreductase	oorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_848479_1	411154.GFO_2998	0.0	916.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_848479_2	411154.GFO_2999	1.01e-25	105.0	COG0784@1|root,COG1520@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1520@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NK8Q@976|Bacteroidetes,1IMWE@117743|Flavobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HTH_18,Reg_prop,SpoIIE,Y_Y_Y
k59_1639890_1	362418.IW19_16010	1.99e-147	448.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia,2P016@237|Flavobacterium	976|Bacteroidetes	KT	Regulator	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_1639890_2	991.IW20_15140	8.58e-62	213.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2NSFC@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1243929_1	411154.GFO_1091	1.61e-85	258.0	2D59T@1|root,32TIK@2|Bacteria,4NNIG@976|Bacteroidetes,1I44A@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
k59_1187944_1	411154.GFO_3589	7.4e-142	411.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,1HYS1@117743|Flavobacteriia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
k59_397152_1	1121875.KB907549_gene1714	2.17e-99	299.0	28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_397152_2	745718.JADT01000008_gene3158	1.25e-36	139.0	COG4206@1|root,COG4206@2|Bacteria,4PM79@976|Bacteroidetes,1IJK7@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1853_1	944547.ABLL_1474	2.94e-67	231.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_453645_1	1178825.ALIH01000010_gene460	1.01e-66	208.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1I2WH@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_453645_2	1178825.ALIH01000010_gene461	5.2e-94	276.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_171233_1	1191523.MROS_0213	7.05e-137	391.0	COG0090@1|root,COG0090@2|Bacteria	2|Bacteria	J	rRNA binding	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_1301011_1	411154.GFO_2213	5.06e-93	285.0	COG0365@1|root,COG0365@2|Bacteria,4NG1Y@976|Bacteroidetes,1HY01@117743|Flavobacteriia	976|Bacteroidetes	I	Pfam GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_227711_1	313606.M23134_00034	3.66e-42	156.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
k59_171245_1	1123037.AUDE01000005_gene3063	1.27e-106	327.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_792459_1	1034807.FBFL15_1314	4.33e-44	159.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,2NT4M@237|Flavobacterium	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
k59_905602_1	90814.KL370891_gene483	4.44e-16	78.2	COG3950@1|root,COG4938@1|root,COG3950@2|Bacteria,COG4938@2|Bacteria,1NEEG@1224|Proteobacteria,1RZWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
k59_1752832_1	411154.GFO_1909	7e-125	361.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_566536_1	926556.Echvi_3816	1.76e-209	591.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
k59_1886_1	998674.ATTE01000001_gene108	4.42e-65	211.0	COG1653@1|root,COG1653@2|Bacteria,1N98V@1224|Proteobacteria,1RMSG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_1583333_1	317025.Tcr_0814	2.06e-144	420.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,45ZPU@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_453686_1	1270193.JARP01000002_gene628	4.23e-21	93.2	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1HZCR@117743|Flavobacteriia,2NV14@237|Flavobacterium	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_453686_2	616991.JPOO01000001_gene4416	1.96e-26	106.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1HYCR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
k59_1301040_1	1121931.AUHG01000011_gene2303	7.87e-100	302.0	2DR29@1|root,339VD@2|Bacteria,4NZEP@976|Bacteroidetes,1I852@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1469969_1	1121957.ATVL01000008_gene4127	2.55e-21	95.9	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_58334_1	1347342.BN863_24650	1.41e-206	590.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_1243972_1	746697.Aeqsu_3178	7.34e-73	230.0	COG0701@1|root,COG0701@2|Bacteria,4NI2E@976|Bacteroidetes,1HX5I@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1243972_2	1121890.AUDO01000008_gene2727	1.73e-46	157.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia,2NV4Z@237|Flavobacterium	976|Bacteroidetes	K	AraC family transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_1243972_3	224719.Abm4_0129	0.000141	45.1	arCOG02763@1|root,arCOG02763@2157|Archaea,2Y8CF@28890|Euryarchaeota,23PZN@183925|Methanobacteria	183925|Methanobacteria	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_624756_2	991905.SL003B_2156	7.51e-08	52.8	COG0683@1|root,COG0683@2|Bacteria,1MWYP@1224|Proteobacteria,2TTAM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_568044_1	1454004.AW11_02703	6.36e-59	196.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2VPY3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_1020284_1	1137281.D778_02729	2.81e-70	212.0	COG0599@1|root,COG0599@2|Bacteria,4NNPC@976|Bacteroidetes,1I1X3@117743|Flavobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1020284_2	1122225.AULQ01000004_gene2024	2.91e-158	450.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,1HXPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
k59_863038_1	1406840.Q763_09725	1.53e-269	789.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,1HZXU@117743|Flavobacteriia,2NTUX@237|Flavobacterium	976|Bacteroidetes	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
k59_1654363_1	1208321.D104_04900	4.76e-57	189.0	COG1172@1|root,COG1172@2|Bacteria,1MUM6@1224|Proteobacteria,1RRCX@1236|Gammaproteobacteria,1XNRD@135619|Oceanospirillales	135619|Oceanospirillales	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_1088107_1	1123037.AUDE01000006_gene1086	1.43e-171	496.0	COG0531@1|root,COG0531@2|Bacteria,4NHS2@976|Bacteroidetes,1HX4J@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_1088107_2	1178825.ALIH01000015_gene1921	4.28e-131	379.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,1HXMM@117743|Flavobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_1088107_3	1131812.JQMS01000001_gene2233	2.32e-91	276.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1HYT2@117743|Flavobacteriia,2NV1V@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
k59_1370559_2	1380600.AUYN01000009_gene1176	2.17e-270	743.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1HX18@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1370559_3	1122225.AULQ01000004_gene2109	0.0	1019.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_72901_1	1123514.KB905899_gene1684	3.18e-88	276.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,460CE@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_186061_1	317025.Tcr_2038	9.14e-129	389.0	COG1251@1|root,COG1740@1|root,COG1251@2|Bacteria,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,462CC@72273|Thiotrichales	72273|Thiotrichales	C	Hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_1598284_1	1122225.AULQ01000001_gene1464	3.07e-89	272.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
k59_1598284_2	1197477.IA57_01000	5.23e-52	164.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1I3YC@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL31 family	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_1598284_3	391603.FBALC1_11822	4.98e-64	201.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,1I2ZA@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
k59_1598284_4	504487.JCM19302_1052	1.75e-67	213.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1767549_2	326298.Suden_0203	1.59e-50	163.0	COG1516@1|root,COG1516@2|Bacteria,1PSYY@1224|Proteobacteria,42V8K@68525|delta/epsilon subdivisions,2YQ35@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k59_1767549_3	1537917.JU82_09605	1.09e-14	73.9	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_637702_1	269799.Gmet_2889	1.92e-67	210.0	COG1497@1|root,COG1497@2|Bacteria,1QXN4@1224|Proteobacteria,43C48@68525|delta/epsilon subdivisions,2X7EN@28221|Deltaproteobacteria,43V1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
k59_919206_1	1380384.JADN01000008_gene1254	2.77e-84	264.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1HX1F@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde	-	-	1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220	-	R00264,R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_919206_2	1178825.ALIH01000001_gene2457	3.99e-179	503.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1I05Z@117743|Flavobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_919206_3	1121887.AUDK01000002_gene2035	3.48e-37	133.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NGHV@976|Bacteroidetes,1HZ93@117743|Flavobacteriia,2NVF5@237|Flavobacterium	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
k59_580982_1	985255.APHJ01000021_gene1559	9.88e-99	304.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1IIH2@117743|Flavobacteriia	976|Bacteroidetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_354201_1	1355374.JARU01000004_gene1304	5.98e-34	132.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_15128_1	1232410.KI421428_gene1107	1.38e-16	78.6	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria,43USH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
k59_15128_2	1232410.KI421428_gene1106	1.86e-53	175.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,43UPX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Oxidoreductase NAD-binding domain	hyhG	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_1316065_2	1380600.AUYN01000001_gene2534	1.85e-63	213.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_1258220_1	85643.Tmz1t_3382	2.52e-72	224.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KUAU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_1258220_2	85643.Tmz1t_3383	1.01e-20	91.7	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KUKU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_411470_1	1191523.MROS_1552	3.48e-91	278.0	COG0172@1|root,COG0172@2|Bacteria	2|Bacteria	J	seryl-tRNA aminoacylation	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_524180_1	1380600.AUYN01000009_gene1919	2.44e-173	511.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_637728_1	90814.KL370891_gene665	1.37e-104	318.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,460RM@72273|Thiotrichales	72273|Thiotrichales	N	Flagellar hook protein FlgE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_637728_2	90814.KL370891_gene664	4.09e-05	44.7	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,4617F@72273|Thiotrichales	72273|Thiotrichales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
k59_298531_1	504487.JCM19302_3449	2.11e-65	202.0	2DZIC@1|root,32VBG@2|Bacteria,4NSX0@976|Bacteroidetes,1I3WV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_298531_2	1392490.JHZX01000001_gene2258	7.18e-44	147.0	2DBJ2@1|root,32TXJ@2|Bacteria,4NTRP@976|Bacteroidetes,1I43A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_298531_3	1124780.ANNU01000033_gene1311	1.06e-99	320.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47M5Y@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_694772_1	411154.GFO_0755	8.85e-179	511.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1HY79@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalase	treA	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase,Trehalase_Ca-bi
k59_919223_1	1123518.ARWI01000001_gene2408	1.28e-166	470.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,4600W@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_637730_1	1127673.GLIP_2376	1.53e-79	245.0	COG0507@1|root,COG0507@2|Bacteria,1NRQU@1224|Proteobacteria,1SM27@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4145)	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145
k59_468398_1	1123228.AUIH01000006_gene2161	5.72e-64	210.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XHNV@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
k59_1598331_1	1172190.M947_01780	9.32e-29	117.0	2AJGC@1|root,31A2T@2|Bacteria,1Q4TA@1224|Proteobacteria,42ZUH@68525|delta/epsilon subdivisions,2YRV9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_468404_1	498211.CJA_3664	3.77e-84	265.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1FFSA@10|Cellvibrio	1236|Gammaproteobacteria	T	Elongation factor G C-terminus	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_128651_1	1249997.JHZW01000003_gene3640	8.16e-233	644.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1HWMU@117743|Flavobacteriia,2PG28@252356|Maribacter	976|Bacteroidetes	J	Elongation factor Tu C-terminal domain	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_1316106_1	1392488.JHZY01000002_gene913	2.96e-29	111.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1HY7N@117743|Flavobacteriia,2XJ1R@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	pabB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1316106_2	504487.JCM19302_3963	2.73e-44	152.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
k59_637760_1	572480.Arnit_1136	1.29e-99	298.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_1144766_1	504487.JCM19302_3800	1.09e-59	184.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1144766_2	1380600.AUYN01000006_gene600	4.65e-173	491.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_411522_1	566466.NOR53_3630	3.3e-07	55.1	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,1SWNI@1236|Gammaproteobacteria,1J917@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,HAD
k59_411522_2	929713.NIASO_11020	2.54e-14	68.6	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_581051_1	926559.JoomaDRAFT_2354	1.09e-72	242.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_1710949_1	1121931.AUHG01000012_gene2947	1.02e-191	541.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_186154_1	1347392.CCEZ01000015_gene2859	3.7e-43	151.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia,36EAE@31979|Clostridiaceae	186801|Clostridia	K	Phage antirepressor protein	-	-	-	ko:K07741	-	-	-	-	ko00000	-	-	-	ANT,Bro-N
k59_973628_1	90814.KL370891_gene604	6.28e-129	385.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales	72273|Thiotrichales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_863185_1	1279017.AQYJ01000024_gene1142	7.88e-19	83.2	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,4652M@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_0608	CoA_binding,Ligase_CoA
k59_749932_1	1237149.C900_03265	3.96e-20	88.6	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_749932_2	1237149.C900_03266	2.42e-85	254.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase membrane protein	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
k59_637818_1	317025.Tcr_1471	2.32e-56	193.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,460RM@72273|Thiotrichales	72273|Thiotrichales	N	Flagellar hook protein FlgE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_15228_1	216432.CA2559_08526	1.03e-05	48.1	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I28K@117743|Flavobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k59_15228_2	1232410.KI421415_gene3025	1.98e-24	99.4	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2WJ1R@28221|Deltaproteobacteria,43SF0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_1088255_1	1121931.AUHG01000011_gene1774	1.07e-99	316.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_637825_1	572480.Arnit_2758	2.68e-26	102.0	COG0745@1|root,COG0745@2|Bacteria,1Q4FE@1224|Proteobacteria,42Z2X@68525|delta/epsilon subdivisions,2YR93@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_637825_2	572480.Arnit_2759	3.44e-94	281.0	COG0147@1|root,COG0147@2|Bacteria,1R5Y8@1224|Proteobacteria,42P2B@68525|delta/epsilon subdivisions,2YMFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
k59_411581_1	1178825.ALIH01000005_gene276	4.32e-35	124.0	COG1247@1|root,COG1247@2|Bacteria,4NPIE@976|Bacteroidetes,1I2DZ@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphinothricin acetyltransferase	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
k59_411581_2	1380600.AUYN01000003_gene46	5.73e-107	310.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_242618_1	387092.NIS_1028	0.000537	42.0	29ZBM@1|root,30MA5@2|Bacteria,1QB0B@1224|Proteobacteria,42XGS@68525|delta/epsilon subdivisions,2YQT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_242618_2	929558.SMGD1_0290	2.6e-61	197.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2YMRK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_524302_1	1178825.ALIH01000006_gene1443	1.31e-191	557.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1088273_1	1249975.JQLP01000005_gene1138	8.91e-31	112.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2P6KK@244698|Gillisia	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_354363_1	1121405.dsmv_2418	1.16e-93	279.0	COG0600@1|root,COG0600@2|Bacteria,1NDW4@1224|Proteobacteria,42PPI@68525|delta/epsilon subdivisions,2WMA3@28221|Deltaproteobacteria,2MI72@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_298672_1	1123326.JFBL01000012_gene133	2.72e-117	368.0	COG0715@1|root,COG2199@1|root,COG3221@1|root,COG0715@2|Bacteria,COG3221@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43D09@68525|delta/epsilon subdivisions,2YPBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	PT	TIGRFAM diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,Phosphonate-bd
k59_807317_1	1380600.AUYN01000009_gene1928	2.42e-150	431.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1258373_1	504487.JCM19302_1791	2.93e-73	228.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1769914_1	1095749.HMPREF1052_0544	2.71e-08	55.1	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1Y71P@135625|Pasteurellales	135625|Pasteurellales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_244875_1	563040.Saut_1537	6.62e-21	84.3	COG2501@1|root,COG2501@2|Bacteria,1PFA5@1224|Proteobacteria,42XJ3@68525|delta/epsilon subdivisions,2YS84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k59_413763_1	945713.IALB_2927	1.88e-16	84.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,CBM_6,DUF1565,PDZ_2,Trypsin_2
k59_809536_1	1298593.TOL_0800	1.9e-34	132.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XHGA@135619|Oceanospirillales	135619|Oceanospirillales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_1542419_1	985255.APHJ01000021_gene1813	3.37e-120	360.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1HXFY@117743|Flavobacteriia,2P627@244698|Gillisia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	yngK	-	-	-	-	-	-	-	-	-	-	-	GHL10
k59_697215_1	313603.FB2170_10284	8.49e-53	181.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia,2PHHE@252356|Maribacter	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_75437_1	1380600.AUYN01000001_gene2915	6.57e-55	178.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
k59_1600697_1	1353528.DT23_12170	2.68e-85	254.0	COG1309@1|root,COG1309@2|Bacteria,1R6X5@1224|Proteobacteria,2U7EK@28211|Alphaproteobacteria,2XN6V@285107|Thioclava	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1318452_1	1123228.AUIH01000010_gene3936	7.56e-54	179.0	COG2770@1|root,COG2770@2|Bacteria,1QZYS@1224|Proteobacteria	1224|Proteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP
k59_17319_1	392500.Swoo_3207	3.88e-123	353.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,2QAQH@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM OmpW family protein	ompW	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_1656765_1	1121931.AUHG01000012_gene2628	8.39e-100	303.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,1HZQ1@117743|Flavobacteriia	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
k59_300928_1	391603.FBALC1_00567	3.46e-57	205.0	COG1404@1|root,COG2356@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,MAM,Peptidase_M43,Peptidase_S8,fn3
k59_809572_1	1380600.AUYN01000006_gene349	7.62e-119	355.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_809572_2	1380600.AUYN01000006_gene348	5.33e-105	338.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_880767_1	1380600.AUYN01000009_gene1605	4.46e-172	484.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_1209452_1	1565129.JSFF01000034_gene1501	1.67e-95	294.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,2Q91K@267890|Shewanellaceae	1236|Gammaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_31888_1	1565129.JSFF01000014_gene442	8.1e-130	378.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,2Q9IJ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the citrate synthase family	gltA	GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_00727	Citrate_synt
k59_1728463_1	317025.Tcr_0537	3.13e-12	66.6	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,460B9@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_1728463_2	1168067.JAGP01000001_gene603	1.11e-152	439.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,45ZRY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1388161_1	498211.CJA_1529	2.17e-57	185.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,1FH6A@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function, DUF480	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k59_1388161_2	1120970.AUBZ01000030_gene3058	3.27e-41	141.0	COG0834@1|root,COG0834@2|Bacteria,1RD01@1224|Proteobacteria,1S43D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_1557535_1	929558.SMGD1_1778	1.65e-100	294.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,42RFD@68525|delta/epsilon subdivisions,2YP9Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_1728469_1	1150621.SMUL_1519	4.13e-09	62.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2YM8Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,MCPsignal,dCache_1
k59_1672132_1	326298.Suden_1601	2e-58	191.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2YN0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Potassium channel protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_1672132_2	1172190.M947_03660	2.91e-42	148.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2YMJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_1209465_1	1121875.KB907547_gene3049	1.5e-83	256.0	COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,1I05E@117743|Flavobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_371622_1	903818.KI912269_gene50	7.76e-25	108.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria	57723|Acidobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_988955_1	411154.GFO_2145	1.08e-153	433.0	COG1051@1|root,COG1051@2|Bacteria,4NE29@976|Bacteroidetes,1HZ34@117743|Flavobacteriia	976|Bacteroidetes	F	COG1051 ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_767170_1	1026882.MAMP_00452	2.09e-47	159.0	COG1865@1|root,COG1865@2|Bacteria,1RJXU@1224|Proteobacteria,1SBM6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Adenosylcobinamide amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CbiZ
k59_429208_2	317025.Tcr_1018	2.15e-123	354.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1S53U@1236|Gammaproteobacteria,4613S@72273|Thiotrichales	72273|Thiotrichales	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1105766_2	1121405.dsmv_0026	3.51e-40	136.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_429218_1	411154.GFO_3326	5.47e-229	637.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia	976|Bacteroidetes	G	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_316496_1	929558.SMGD1_2556	5.52e-124	356.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	racR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1557565_1	929558.SMGD1_1335	4.61e-110	331.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2YR2K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
k59_1444741_1	929558.SMGD1_2362	1.57e-45	157.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,42R3P@68525|delta/epsilon subdivisions,2YPBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COGs COG2829 Outer membrane phospholipase A	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_1444741_2	929558.SMGD1_2361	1.73e-105	307.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2YNXZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_1444741_3	563040.Saut_1411	2.47e-60	197.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2YP2R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	MltA specific insert domain	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_988981_1	1249997.JHZW01000002_gene663	5.56e-08	55.8	2E78C@1|root,331S1@2|Bacteria,4NPWT@976|Bacteroidetes,1I2MW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_988981_2	869213.JCM21142_3823	6.25e-07	50.8	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,4NF52@976|Bacteroidetes,47NEH@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0471 Di- and tricarboxylate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_767195_1	1178825.ALIH01000008_gene757	2.73e-75	229.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_767195_2	1380384.JADN01000004_gene1942	2.7e-32	118.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,1HX59@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_90659_1	1250006.JHZZ01000001_gene2491	1.48e-86	261.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1HXEB@117743|Flavobacteriia,3VW8Z@52959|Polaribacter	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_714290_1	1187848.AJYQ01000120_gene1253	1.34e-43	164.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
k59_1672179_1	1121931.AUHG01000010_gene863	3.38e-85	260.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1HXE0@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_1672179_2	1250278.JQNQ01000001_gene1469	7.6e-81	243.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1I1AX@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_145951_1	929558.SMGD1_0905	1.97e-47	160.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
k59_145951_2	929558.SMGD1_0904	4.19e-11	62.8	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2YMKB@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_655506_1	313595.P700755_001306	5.79e-124	368.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1HZF1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_1209507_1	1380600.AUYN01000009_gene2020	6.02e-67	209.0	2E6PN@1|root,331A0@2|Bacteria,4NUUD@976|Bacteroidetes,1I5A3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1209507_2	1178825.ALIH01000005_gene149	2.21e-31	117.0	28JHY@1|root,2Z9BE@2|Bacteria,4NGKG@976|Bacteroidetes,1I1EX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1388223_1	563040.Saut_0660	1.19e-140	415.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_1275971_1	90814.KL370891_gene54	2.4e-299	831.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4607X@72273|Thiotrichales	72273|Thiotrichales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_714341_1	1353528.DT23_07185	2.36e-92	280.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2XKR6@285107|Thioclava	28211|Alphaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_1444802_1	90814.KL370891_gene1837	5.79e-54	181.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,45ZQS@72273|Thiotrichales	72273|Thiotrichales	F	dihydroorotase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1444802_2	90814.KL370891_gene1840	1.82e-49	159.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_1444802_3	317025.Tcr_1891	1.9e-30	119.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_714350_1	572480.Arnit_1584	3.24e-31	120.0	COG0697@1|root,COG0697@2|Bacteria,1PIFB@1224|Proteobacteria,42QAN@68525|delta/epsilon subdivisions,2YNGI@29547|Epsilonproteobacteria	2|Bacteria	EG	integral membrane protein (DUF6 domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_714350_2	572480.Arnit_1593	2.47e-44	153.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YNN9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_767264_1	1123326.JFBL01000001_gene1377	3.21e-46	167.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42TH4@68525|delta/epsilon subdivisions,2YRFX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3
k59_1503273_1	709032.Sulku_2495	1.53e-118	348.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2YRAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k59_989049_1	317025.Tcr_1803	1.16e-133	382.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,1S357@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_989049_2	1123514.KB905899_gene1365	1.27e-50	169.0	COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria,4624H@72273|Thiotrichales	72273|Thiotrichales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
k59_1444806_1	1323663.AROI01000009_gene3742	4.72e-100	304.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_1785756_1	929558.SMGD1_2246	1.88e-109	319.0	COG2215@1|root,COG2215@2|Bacteria,1Q5AP@1224|Proteobacteria,42R81@68525|delta/epsilon subdivisions,2YP06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1672237_1	326297.Sama_1147	9.87e-59	200.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,2Q8GK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1672237_2	323850.Shew_2626	3.99e-39	134.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,2Q8RP@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the skp family	skp	GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_826112_1	572480.Arnit_1709	8.38e-90	271.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2YMUA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_597800_1	572480.Arnit_0817	1.51e-49	175.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_597800_2	572480.Arnit_0816	2.83e-51	168.0	2AFRW@1|root,315TV@2|Bacteria,1PW73@1224|Proteobacteria,42ZYA@68525|delta/epsilon subdivisions,2YRUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_260764_1	323850.Shew_2930	9.89e-18	78.2	COG2980@1|root,COG2980@2|Bacteria,1N0JN@1224|Proteobacteria,1SAG4@1236|Gammaproteobacteria,2QBXF@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
k59_260764_2	323850.Shew_2929	2.52e-53	185.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,2Q8KU@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_429334_1	1565129.JSFF01000047_gene604	2.28e-71	223.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,2Q8HB@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k59_1105884_1	1172190.M947_02205	1.26e-95	291.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2YMM2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_263286_2	688270.Celal_3947	3.76e-80	240.0	COG1764@1|root,COG1764@2|Bacteria,4PK2J@976|Bacteroidetes,1IGFZ@117743|Flavobacteriia,1FAMJ@104264|Cellulophaga	976|Bacteroidetes	O	PFAM Peroxiredoxin, OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_263286_3	1122225.AULQ01000006_gene1071	2.63e-121	354.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,1I071@117743|Flavobacteriia	976|Bacteroidetes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1674845_1	1144313.PMI10_00817	8.33e-06	52.4	2E4RS@1|root,32ZKA@2|Bacteria,4NVN5@976|Bacteroidetes,1I5GH@117743|Flavobacteriia,2NVTV@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1390955_1	563040.Saut_0489	2.42e-101	297.0	2AINN@1|root,31954@2|Bacteria,1NDHA@1224|Proteobacteria,42Z7Y@68525|delta/epsilon subdivisions,2YR4T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_1390955_2	1232683.ADIMK_2673	3.9e-45	164.0	COG2199@1|root,COG2203@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4936@2|Bacteria,1R7HC@1224|Proteobacteria,1RYYR@1236|Gammaproteobacteria,46AFI@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	PAS PAC and GAF sensor-containing diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PocR
k59_991622_2	1353276.JADR01000005_gene2628	4.65e-125	374.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1HX1R@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_1165456_1	317025.Tcr_0181	4.74e-18	83.2	COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,1RRB8@1236|Gammaproteobacteria,461BD@72273|Thiotrichales	72273|Thiotrichales	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
k59_1165456_2	1123518.ARWI01000001_gene1182	4.41e-47	162.0	COG0454@1|root,COG0454@2|Bacteria,1MXMM@1224|Proteobacteria,1T00M@1236|Gammaproteobacteria,462WS@72273|Thiotrichales	72273|Thiotrichales	K	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
k59_828740_1	90814.KL370891_gene1305	1.85e-68	218.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,4604Z@72273|Thiotrichales	72273|Thiotrichales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_828740_2	90814.KL370891_gene1306	1.05e-46	153.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,460JM@72273|Thiotrichales	72273|Thiotrichales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_1165460_1	1121931.AUHG01000012_gene2825	2.37e-100	307.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1HYTA@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_717090_1	640081.Dsui_0378	1.92e-74	237.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VI85@28216|Betaproteobacteria,2KVPK@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidases, C-terminal domain	dldH	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_543997_1	1178825.ALIH01000010_gene421	1.27e-60	197.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
k59_543997_2	1469557.JSWF01000033_gene1609	1.18e-118	351.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_599886_1	1232410.KI421415_gene3122	2.12e-63	209.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_34723_1	1123514.KB905899_gene1470	3.42e-35	129.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,4617R@72273|Thiotrichales	72273|Thiotrichales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_1788380_1	946483.Cenrod_2578	4.45e-48	176.0	COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2203@1|root,COG3614@1|root,COG3829@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG3614@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_1674894_1	563040.Saut_0943	1.25e-75	233.0	COG0596@1|root,COG0596@2|Bacteria,1NH3R@1224|Proteobacteria,42R8Q@68525|delta/epsilon subdivisions,2YNWT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_828781_2	90814.KL370891_gene1093	5.23e-20	82.4	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
k59_938035_1	1178825.ALIH01000019_gene1218	1.85e-40	152.0	2BZQ4@1|root,32TE6@2|Bacteria,4NTHT@976|Bacteroidetes,1I4BF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1447489_1	305700.B447_19084	3.94e-51	168.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,2KUVG@206389|Rhodocyclales	206389|Rhodocyclales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_1771413_1	1347342.BN863_22710	6.36e-34	129.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mexF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1771413_2	1408433.JHXV01000002_gene435	4.4e-157	451.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,1HWZ5@117743|Flavobacteriia,2PASE@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_472435_1	1415778.JQMM01000001_gene2217	2.83e-74	233.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1J5T0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_246424_1	313598.MED152_00755	4.42e-250	743.0	COG5498@1|root,COG5498@2|Bacteria,4NJUD@976|Bacteroidetes,1IG6T@117743|Flavobacteriia,3VW2U@52959|Polaribacter	976|Bacteroidetes	M	Glycosyl hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_81
k59_18707_1	926569.ANT_17590	6.84e-64	219.0	COG3459@1|root,COG3459@2|Bacteria,2G9NQ@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_584508_1	929558.SMGD1_2393	6.46e-77	231.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_584508_2	326298.Suden_1273	8.45e-32	124.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_922802_1	1178825.ALIH01000001_gene2312	6.47e-175	515.0	COG0652@1|root,COG3291@1|root,COG0652@2|Bacteria,COG3291@2|Bacteria,4NMHU@976|Bacteroidetes,1I1EF@117743|Flavobacteriia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,TIG
k59_246428_1	411154.GFO_1831	2.49e-84	251.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia	976|Bacteroidetes	FJ	Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
k59_246428_2	411154.GFO_1830	8.4e-24	99.4	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_1262165_1	1121931.AUHG01000012_gene2934	1.97e-33	124.0	COG0667@1|root,COG0667@2|Bacteria,4NGIT@976|Bacteroidetes,1HWVB@117743|Flavobacteriia	976|Bacteroidetes	C	Aldo/keto reductase family	fdh	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
k59_1262165_2	1121931.AUHG01000012_gene2935	2.41e-52	169.0	2DNTB@1|root,32Z1S@2|Bacteria,4NW5K@976|Bacteroidetes,1I52B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_246447_1	78245.Xaut_1955	4.11e-07	56.2	COG2242@1|root,COG2242@2|Bacteria,1QVKC@1224|Proteobacteria,2TWH7@28211|Alphaproteobacteria,3EZ5F@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	Methyltransferase FkbM domain	MA20_43520	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_641590_1	1392489.JPOL01000002_gene1276	5.58e-69	219.0	COG0657@1|root,COG0657@2|Bacteria,4PKDQ@976|Bacteroidetes,1HXR3@117743|Flavobacteriia,2XJTJ@283735|Leeuwenhoekiella	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_1036504_2	1123355.JHYO01000008_gene2684	2.77e-87	264.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,36XHC@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_1431359_1	572480.Arnit_1396	1.17e-98	303.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2YMIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k59_753450_1	582744.Msip34_0969	9.33e-79	239.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2VH6D@28216|Betaproteobacteria,2KM8N@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_302553_1	1380600.AUYN01000009_gene1929	1.65e-124	369.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_1771464_1	1137281.D778_02481	9.89e-111	342.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_246480_1	402612.FP1308	3.56e-10	59.7	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia,2NS60@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_246480_2	1492738.FEM21_14700	1.42e-209	586.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia,2NT0Z@237|Flavobacterium	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_1543814_1	398579.Spea_3531	2.53e-203	579.0	COG1629@1|root,COG4771@2|Bacteria,1MXY7@1224|Proteobacteria,1RSFW@1236|Gammaproteobacteria,2QCMA@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	prrA	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_811298_1	326297.Sama_2307	6.58e-32	118.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,2Q8U1@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaA	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_811298_2	323850.Shew_1358	3.48e-13	67.0	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,1SDCC@1236|Gammaproteobacteria,2QCZG@267890|Shewanellaceae	1236|Gammaproteobacteria	N	PFAM flagellar protein FlaG protein	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_1714916_1	1121931.AUHG01000019_gene3077	6.32e-94	293.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
k59_132276_1	945713.IALB_2692	7.32e-57	188.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	BetaGal_dom4_5,F5_F8_type_C
k59_132276_2	945713.IALB_2691	1.86e-05	47.8	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
k59_528148_1	1123518.ARWI01000001_gene1548	2.4e-235	666.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,45ZQ4@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1262228_1	326298.Suden_0557	1.3e-69	214.0	2A067@1|root,30N97@2|Bacteria,1Q1X8@1224|Proteobacteria,42UM9@68525|delta/epsilon subdivisions,2YPYZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1091920_1	1117319.PSPO_05386	2.94e-68	240.0	COG2831@1|root,COG2831@2|Bacteria,1MWWH@1224|Proteobacteria,1RREH@1236|Gammaproteobacteria,2Q0UA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	PFAM Ig domain protein, group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
k59_1264151_1	926559.JoomaDRAFT_2965	7.98e-152	437.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia	976|Bacteroidetes	H	cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_1264151_2	926559.JoomaDRAFT_2966	0.0	958.0	COG0323@1|root,COG0323@2|Bacteria,4NHAV@976|Bacteroidetes,1I10S@117743|Flavobacteriia	976|Bacteroidetes	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k59_1264151_3	926559.JoomaDRAFT_2967	8.01e-179	517.0	COG1100@1|root,COG1100@2|Bacteria,4NHD1@976|Bacteroidetes,1HZW7@117743|Flavobacteriia	976|Bacteroidetes	L	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
k59_1093807_1	1172190.M947_08855	2.54e-91	277.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2YMIC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_1093807_2	1144319.PMI16_02973	4.91e-34	132.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,472P3@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_191894_1	1122225.AULQ01000009_gene300	2.25e-19	84.7	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1HZU1@117743|Flavobacteriia	976|Bacteroidetes	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_248520_1	1121912.AUHD01000005_gene1691	3.86e-74	235.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_813585_1	1537915.JU57_01975	6.57e-88	270.0	COG0226@1|root,COG0226@2|Bacteria,1PGT2@1224|Proteobacteria,42SFT@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	MUG113,T5orf172
k59_20662_1	1137281.D778_02136	2.23e-15	72.8	2C8TJ@1|root,32RMV@2|Bacteria,4NSAA@976|Bacteroidetes,1I54A@117743|Flavobacteriia	976|Bacteroidetes	S	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k59_20662_2	504487.JCM19302_3698	2.22e-22	93.6	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_1773610_1	929558.SMGD1_0141	2.58e-146	424.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2YNEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Membrane-bound lytic murein transglycosylase C	mltC	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k59_924762_1	225849.swp_1743	1.39e-117	347.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,1RNSS@1236|Gammaproteobacteria,2Q9XH@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009015,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_2463,iECSP_1301.ECSP_2313,iECs_1301.ECs2451,iG2583_1286.G2583_2191	AstB
k59_1545839_1	983544.Lacal_2427	1.98e-79	258.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_417383_1	1165841.SULAR_01823	6.93e-90	275.0	2CEAP@1|root,3322D@2|Bacteria,1N7SG@1224|Proteobacteria,42WE8@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_417394_1	926559.JoomaDRAFT_3919	4.21e-52	179.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_417394_2	1380600.AUYN01000009_gene2039	2.58e-49	158.0	2E695@1|root,330X7@2|Bacteria,4NVE0@976|Bacteroidetes,1I53C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1093848_1	1250232.JQNJ01000001_gene2827	2.79e-33	123.0	2ATWF@1|root,31JFP@2|Bacteria,4NQ9K@976|Bacteroidetes,1I3SN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_191933_1	323850.Shew_2166	4.73e-68	230.0	COG2911@1|root,COG2911@2|Bacteria,1MUT7@1224|Proteobacteria,1RQ5W@1236|Gammaproteobacteria,2Q9KP@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Dicarboxylate transport	ydbH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
k59_1433200_1	203122.Sde_2127	2.28e-88	269.0	2CCXX@1|root,2Z8MY@2|Bacteria,1RE6D@1224|Proteobacteria,1S3GM@1236|Gammaproteobacteria,46AQ2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	NDP-hexose 2,3-dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Hexose_dehydrat
k59_1433200_2	1124991.MU9_250	8.64e-59	189.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rffH	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iUMNK88_1353.UMNK88_4598,iYL1228.KPN_04289	NTP_transferase
k59_1376378_1	298386.PBPRB1987	1.75e-49	178.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,1RN7D@1236|Gammaproteobacteria,1XV5V@135623|Vibrionales	135623|Vibrionales	U	COG0823 Periplasmic component of the Tol biopolymer transport system	VVA0929	-	-	-	-	-	-	-	-	-	-	-	-
k59_924799_1	360910.BAV2652	8.38e-23	102.0	COG1835@1|root,COG1835@2|Bacteria,1RICE@1224|Proteobacteria,2VV24@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_1322245_1	177437.HRM2_46500	4.6e-40	147.0	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2MHRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_79055_1	1250005.PHEL85_3041	5.28e-163	485.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia,3VX76@52959|Polaribacter	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_248575_1	572480.Arnit_1949	6.91e-09	63.5	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,42SEW@68525|delta/epsilon subdivisions,2YPKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_869118_1	945713.IALB_0623	6.8e-14	71.2	COG0621@1|root,COG0621@2|Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_869118_2	518766.Rmar_2371	7.82e-11	65.9	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidase_6,LysM,PD40,Peptidase_M23,Peptidase_M56
k59_134118_1	317025.Tcr_1099	1.13e-97	295.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,45ZSN@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_1093873_1	1123518.ARWI01000001_gene106	2.04e-91	273.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1S5D0@1236|Gammaproteobacteria,462MD@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k59_1773665_1	458817.Shal_2451	2.9e-92	274.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,2Q9X9@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran
k59_1202175_1	1124780.ANNU01000008_gene2618	2.77e-96	293.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47K1B@768503|Cytophagia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k59_1150289_2	1123514.KB905899_gene635	7.25e-59	196.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4604A@72273|Thiotrichales	72273|Thiotrichales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_248594_1	888832.HMPREF9420_0693	2.52e-13	63.9	COG1773@1|root,COG1773@2|Bacteria,4NHF0@976|Bacteroidetes,2FUN6@200643|Bacteroidia	976|Bacteroidetes	C	rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_248594_2	990073.ATHU01000001_gene1787	2.86e-56	182.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2YNF7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k59_978029_1	929558.SMGD1_0382	1.53e-99	296.0	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,42SZX@68525|delta/epsilon subdivisions,2YTRV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
k59_978029_2	929558.SMGD1_0383	1.06e-26	103.0	COG1413@1|root,COG1413@2|Bacteria,1RIZR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_924854_1	1353528.DT23_03140	2.73e-85	265.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2TUW3@28211|Alphaproteobacteria,2XMY1@285107|Thioclava	28211|Alphaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_304639_2	1327982.S0A133_9CAUD	1.93e-50	167.0	4QAMW@10239|Viruses,4QV5I@35237|dsDNA viruses  no RNA stage,4QRGE@28883|Caudovirales,4QN0Q@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_813695_1	1123514.KB905902_gene231	2.17e-98	294.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_586539_1	643867.Ftrac_1606	1.42e-68	217.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,47K34@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_586539_2	269798.CHU_1087	1.49e-12	67.4	COG0644@1|root,COG0644@2|Bacteria,4NKR8@976|Bacteroidetes,47SE4@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM geranylgeranyl reductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
k59_1093940_1	1123517.JOMR01000001_gene906	6.44e-10	56.6	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,460JM@72273|Thiotrichales	72273|Thiotrichales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_1093940_2	90814.KL370891_gene1307	2.01e-257	709.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,45ZMT@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_20787_1	313603.FB2170_14803	1e-16	78.6	COG1142@1|root,COG1142@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3,cNMP_binding
k59_304660_1	760192.Halhy_4940	9.81e-14	72.4	COG0745@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_304660_2	945713.IALB_0293	1.44e-11	65.5	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,HYR,Laminin_G_3,Peptidase_M14
k59_530349_1	98439.AJLL01000013_gene1030	2.46e-66	218.0	COG0146@1|root,COG0146@2|Bacteria,1GCWJ@1117|Cyanobacteria,1JK9Y@1189|Stigonemataceae	1117|Cyanobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_755420_1	323850.Shew_2452	1.08e-11	65.1	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2QAPY@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the DEAD box helicase family	srmB	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_755420_2	1565129.JSFF01000001_gene1197	3.09e-51	164.0	2ASWM@1|root,31IC3@2|Bacteria,1N1F9@1224|Proteobacteria,1S798@1236|Gammaproteobacteria,2QBMF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3010)	SO2839	-	-	-	-	-	-	-	-	-	-	-	DUF3010
k59_813732_2	326298.Suden_0483	1.88e-06	48.1	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_869203_1	1298593.TOL_0610	9.54e-102	313.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1XI3R@135619|Oceanospirillales	135619|Oceanospirillales	NU	secretion pathway protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_1604743_1	391603.FBALC1_05518	8.31e-40	149.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_1093975_1	443143.GM18_2601	3.45e-34	133.0	COG3170@1|root,COG3170@2|Bacteria,1MY6X@1224|Proteobacteria,42TBE@68525|delta/epsilon subdivisions,2WPBV@28221|Deltaproteobacteria,43U5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_978076_1	439235.Dalk_0297	2.21e-18	90.9	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHWA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_79140_1	1380600.AUYN01000009_gene1534	1.17e-142	424.0	COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,1HZCD@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1604754_1	1353276.JADR01000007_gene1411	2.63e-47	160.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,1HY5E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
k59_1604754_2	742741.HMPREF9475_00580	0.000179	46.2	COG1215@1|root,COG1215@2|Bacteria,1U4ZW@1239|Firmicutes	1239|Firmicutes	M	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1787245_2	1123518.ARWI01000001_gene2253	2.22e-76	228.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,460WP@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_1787245_4	1123518.ARWI01000001_gene2252	9.6e-38	129.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,46176@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_1787245_5	90814.KL370891_gene1413	1.39e-84	255.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,4608G@72273|Thiotrichales	72273|Thiotrichales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_543111_1	391603.FBALC1_15872	1.97e-77	231.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_543111_2	1155714.KB891999_gene258	0.000181	44.3	COG0730@1|root,COG0730@2|Bacteria,2GK5W@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_430844_1	758.BBIX01000006_gene740	1.13e-134	435.0	COG3209@1|root,COG3501@1|root,COG3209@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1Y9W8@135625|Pasteurellales	135625|Pasteurellales	M	RHS protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD,RHS,RHS_repeat
k59_1336297_1	563040.Saut_1575	4.52e-86	256.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,42QUT@68525|delta/epsilon subdivisions,2YNVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_1336297_2	929558.SMGD1_1944	3.66e-88	262.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2YPEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iIT341.HP0860	HAD_2,Hydrolase_like,PNK3P
k59_1336297_3	572480.Arnit_1201	1.05e-12	64.7	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2YQ20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EJ	GlutRNAGln amidotransferase subunit D	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_937099_1	929558.SMGD1_1692	3.1e-10	57.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YPSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iIT341.HP1270	Oxidored_q2
k59_937099_2	572480.Arnit_2970	1.2e-81	245.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2YP9Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_882430_1	1249480.B649_06530	1.47e-17	80.9	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2YNM4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k59_882430_2	1249480.B649_04345	1.64e-29	110.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42PC4@68525|delta/epsilon subdivisions,2YP8E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_543117_1	90814.KL370891_gene1871	2.29e-216	630.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZ2Z@1236|Gammaproteobacteria,461N6@72273|Thiotrichales	72273|Thiotrichales	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_9,SBP_bac_3
k59_1446365_1	1537917.JU82_02300	1.04e-238	667.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_262312_1	468059.AUHA01000006_gene3062	7.73e-50	162.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_993212_1	563040.Saut_1127	5.39e-121	357.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_375876_1	1380600.AUYN01000007_gene3349	1.19e-32	114.0	2CKK3@1|root,334WA@2|Bacteria,4NUPS@976|Bacteroidetes,1I56I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_375876_2	641526.ADIWIN_3961	1.09e-161	464.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_1676535_2	563040.Saut_1209	5.63e-38	130.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2YP8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1562006_1	563040.Saut_1127	3.22e-19	86.3	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42NHA@68525|delta/epsilon subdivisions,2YMYU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1562006_2	326298.Suden_1060	9.12e-45	146.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2YQ8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_1280368_1	634956.Geoth_2349	1.49e-52	186.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4HB5P@91061|Bacilli,1WE83@129337|Geobacillus	91061|Bacilli	I	Acetyl-coenzyme A synthetase N-terminus	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_36381_1	1172190.M947_03575	2.1e-50	180.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CBJ@68525|delta/epsilon subdivisions,2YTB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_993272_1	944547.ABLL_2668	3.67e-117	343.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2YNHM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_321023_1	1123514.KB905899_gene1986	2.89e-211	611.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,461S8@72273|Thiotrichales	72273|Thiotrichales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_885302_1	504472.Slin_4331	3.6e-25	106.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,47QZ2@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_95249_1	90814.KL370891_gene141	1.5e-71	235.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1QVWQ@1224|Proteobacteria,1T2KZ@1236|Gammaproteobacteria,463U0@72273|Thiotrichales	72273|Thiotrichales	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_885328_1	929558.SMGD1_2089	7.32e-33	122.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,42QE2@68525|delta/epsilon subdivisions,2YNKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k59_885328_2	563040.Saut_1539	1.85e-23	95.9	COG0745@1|root,COG0745@2|Bacteria,1PGAE@1224|Proteobacteria,4348Y@68525|delta/epsilon subdivisions,2YREY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1562084_1	1211815.CBYP010000062_gene3157	1.16e-29	123.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4ERFZ@85013|Frankiales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_433794_1	572480.Arnit_2412	1.08e-70	226.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2YMT3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretion system	ctsF	-	-	ko:K02455,ko:K02653,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_433794_2	572480.Arnit_2413	1.95e-119	353.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_993319_1	1121931.AUHG01000018_gene1342	9.47e-127	382.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1HYKS@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
k59_1732978_2	398720.MED217_07021	7.16e-40	145.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1HY02@117743|Flavobacteriia,2XK5M@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Sulfatase
k59_993329_1	488538.SAR116_1833	1.48e-28	109.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,4BPEB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_993329_2	1123518.ARWI01000001_gene15	2.98e-98	295.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,45ZUM@72273|Thiotrichales	72273|Thiotrichales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_36478_2	314275.MADE_1008400	1.95e-24	100.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,46442@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_601383_1	643473.KB235930_gene1670	1.95e-19	92.4	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HJ8D@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_264672_1	709032.Sulku_2402	4.94e-43	157.0	2DY8I@1|root,348MR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1449243_3	313603.FB2170_14833	1.35e-172	516.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PG6S@252356|Maribacter	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1733018_1	317025.Tcr_0015	9.61e-50	167.0	COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,1SA0V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k59_1733018_2	314275.MADE_1002370	1.92e-30	116.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,465BY@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_208228_1	1178825.ALIH01000001_gene2530	3.03e-80	243.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1HXWI@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_208228_2	504487.JCM19302_2301	1.12e-73	222.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_208228_3	1178825.ALIH01000001_gene2532	2.46e-113	334.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1HX6B@117743|Flavobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_208228_4	1380600.AUYN01000006_gene358	8.05e-93	282.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1621198_1	1121931.AUHG01000010_gene766	1.47e-149	430.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1HXNI@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_321136_1	439235.Dalk_5047	1.05e-47	175.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2WUAE@28221|Deltaproteobacteria,2MMJK@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_433876_1	929558.SMGD1_2298	2.25e-74	240.0	COG4972@1|root,COG4972@2|Bacteria,1QA6M@1224|Proteobacteria,42NDB@68525|delta/epsilon subdivisions,2YMP2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95370_1	1123518.ARWI01000001_gene475	1.89e-13	71.2	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,461JZ@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_95370_2	1123518.ARWI01000001_gene476	3.34e-132	383.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,461NB@72273|Thiotrichales	72273|Thiotrichales	S	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_545373_1	406340.A4PE29_9CAUD	8.21e-68	217.0	4QDS9@10239|Viruses,4QWGD@35237|dsDNA viruses  no RNA stage,4QS5E@28883|Caudovirales,4QJPI@10662|Myoviridae	10662|Myoviridae	S	Phage capsid scaffolding protein (GPO) serine peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_545378_1	1122207.MUS1_01805	1.12e-66	222.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQMR@1236|Gammaproteobacteria,1XH3C@135619|Oceanospirillales	135619|Oceanospirillales	KQ	transcriptional regulator	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,Sigma54_activat
k59_208270_1	572480.Arnit_1665	3.47e-160	458.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2YNA4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1167320_1	1380600.AUYN01000007_gene3291	1.44e-133	409.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_939535_1	90814.KL370891_gene1735	9.66e-28	110.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_545382_1	1380600.AUYN01000009_gene1905	6.2e-123	362.0	COG0742@1|root,COG0742@2|Bacteria,4NG6E@976|Bacteroidetes,1IJCS@117743|Flavobacteriia	976|Bacteroidetes	L	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,PCMT
k59_545382_2	504487.JCM19302_2393	4.82e-49	166.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,1HYDA@117743|Flavobacteriia	976|Bacteroidetes	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_771664_1	1124780.ANNU01000002_gene1605	1.04e-40	142.0	COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,47UX9@768503|Cytophagia	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
k59_660206_1	929558.SMGD1_1513	2.27e-15	74.7	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2YMGW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144	COX1
k59_1507977_1	1380600.AUYN01000009_gene1761	8.01e-59	206.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1280597_1	929558.SMGD1_1846	1.1e-55	192.0	COG0457@1|root,COG0457@2|Bacteria,1QV15@1224|Proteobacteria,42NKI@68525|delta/epsilon subdivisions,2YMKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0457 FOG TPR repeat	pflB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_1280597_2	929558.SMGD1_1845	8.51e-70	218.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_1507983_1	1249975.JQLP01000005_gene2511	5.03e-37	133.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia,2P66R@244698|Gillisia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_490585_1	1178825.ALIH01000006_gene1438	2.51e-246	682.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucosamine mutase	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1053408_1	1197477.IA57_07410	7.81e-132	384.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_264753_1	457415.HMPREF1006_00804	7.36e-07	53.5	COG0845@1|root,COG0845@2|Bacteria,3T9UB@508458|Synergistetes	508458|Synergistetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_264753_2	640081.Dsui_3177	2.45e-42	145.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,2KVSC@206389|Rhodocyclales	206389|Rhodocyclales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1676778_1	999141.GME_02685	5.16e-27	107.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1XHQC@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_1676778_2	1279017.AQYJ01000023_gene3075	5.19e-37	134.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,4652A@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_545409_1	504487.JCM19302_4127	2.35e-117	362.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia	976|Bacteroidetes	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_1621285_1	641524.ADICYQ_5091	7.84e-14	75.1	2E39A@1|root,32Y8X@2|Bacteria,4NWB4@976|Bacteroidetes,47SFE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
k59_1508026_1	631362.Thi970DRAFT_01109	1.75e-108	323.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_1676809_1	314275.MADE_1015770	3.08e-05	51.6	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464N9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Aerobic respiration control sensor protein	arcB	-	2.7.13.3	ko:K07648	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k59_1508035_1	1123517.JOMR01000001_gene788	3.77e-32	123.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,46053@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM ATPase, FliI YscN family	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1167406_1	458817.Shal_4113	3.52e-42	140.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,2QBVP@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_1167406_2	1236542.BALM01000042_gene4057	1.98e-40	144.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,2QAR6@267890|Shewanellaceae	1236|Gammaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_36656_1	1353276.JADR01000008_gene918	8.63e-40	137.0	COG3212@1|root,COG3212@2|Bacteria,4NR13@976|Bacteroidetes,1I2ZZ@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
k59_36656_2	985255.APHJ01000023_gene2667	8.04e-111	338.0	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia,2P79J@244698|Gillisia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_36656_3	985255.APHJ01000023_gene2664	1.93e-134	411.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1562318_1	572480.Arnit_2420	3.14e-187	530.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_376172_1	1173023.KE650771_gene2031	1.8e-06	47.4	COG4319@1|root,COG4319@2|Bacteria,1G9MH@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_376172_2	1406840.Q763_09675	2.27e-122	348.0	COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes,1I32M@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_376172_3	1406840.Q763_09670	4.25e-96	280.0	COG2050@1|root,COG2050@2|Bacteria,4NUBV@976|Bacteroidetes,1I4ET@117743|Flavobacteriia	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_58418_1	411154.GFO_0242	1.82e-146	424.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1HXCK@117743|Flavobacteriia	976|Bacteroidetes	H	Pfam GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_1074583_1	319224.Sputcn32_3191	8.87e-58	200.0	COG1629@1|root,COG4771@2|Bacteria,1R4PY@1224|Proteobacteria,1RYVW@1236|Gammaproteobacteria,2Q9VM@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k59_1526871_2	571166.KI421509_gene1940	2.37e-17	78.2	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2U6SH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_2,TetR_C_6,TetR_N
k59_736164_1	1123037.AUDE01000009_gene1405	6.01e-24	102.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_736164_2	1380600.AUYN01000009_gene1734	6.1e-125	362.0	COG3712@1|root,COG3712@2|Bacteria,4NH8I@976|Bacteroidetes,1HXP7@117743|Flavobacteriia	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_2000_1	323850.Shew_2410	1.36e-190	535.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,2Q8J6@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869	Ketoacyl-synt_C,ketoacyl-synt
k59_453804_1	1137281.D778_00347	4.94e-54	184.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1HWXI@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
k59_962064_2	1123517.JOMR01000001_gene1342	5.69e-105	316.0	COG3307@1|root,COG3307@2|Bacteria,1Q9AR@1224|Proteobacteria,1RUX5@1236|Gammaproteobacteria,462D4@72273|Thiotrichales	72273|Thiotrichales	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k59_1074601_1	1123518.ARWI01000001_gene1825	2.39e-25	100.0	COG4902@1|root,COG4902@2|Bacteria,1RHUF@1224|Proteobacteria,1S5D0@1236|Gammaproteobacteria,462MD@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k59_1074601_2	396588.Tgr7_0273	1.32e-21	91.7	COG1266@1|root,COG1266@2|Bacteria,1NHPM@1224|Proteobacteria,1SGEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k59_171385_1	411154.GFO_0833	7.93e-05	45.1	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
k59_171385_2	1345023.M467_00635	4.69e-28	113.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4IQ3P@91061|Bacilli	91061|Bacilli	G	Maltogenic Amylase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
k59_1074605_1	1144319.PMI16_04266	1.62e-07	53.5	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,4724U@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1074605_2	1123514.KB905899_gene1579	5.19e-45	157.0	COG3103@1|root,COG3103@2|Bacteria,1QVX2@1224|Proteobacteria,1T2MF@1236|Gammaproteobacteria,4619C@72273|Thiotrichales	72273|Thiotrichales	T	SH3 domain protein	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k59_1074605_3	90814.KL370891_gene535	7.39e-37	131.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,460JH@72273|Thiotrichales	72273|Thiotrichales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_58451_1	504487.JCM19302_904	1.9e-36	128.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1HXX3@117743|Flavobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_58451_2	1286632.P278_16500	1.4e-70	218.0	COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,1I22F@117743|Flavobacteriia	976|Bacteroidetes	J	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
k59_58451_3	1380600.AUYN01000009_gene1641	4.38e-94	279.0	2DB8A@1|root,2Z7R3@2|Bacteria,4PM8J@976|Bacteroidetes,1IJMQ@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_397332_1	1406840.Q763_09625	1.44e-24	99.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1HWKK@117743|Flavobacteriia,2P065@237|Flavobacterium	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_397332_2	1406840.Q763_09620	8.85e-114	338.0	COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,1I02W@117743|Flavobacteriia,2NT2S@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	yjiR	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_905777_1	1249975.JQLP01000001_gene3124	7.05e-11	61.6	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1HYS9@117743|Flavobacteriia,2P68H@244698|Gillisia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug
k59_905777_2	411154.GFO_3161	1.01e-61	202.0	COG4085@1|root,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes,1HWVQ@117743|Flavobacteriia	976|Bacteroidetes	F	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
k59_1188134_1	1123053.AUDG01000005_gene3944	1.18e-109	332.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_340479_1	1123518.ARWI01000001_gene1897	5.39e-132	382.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,45ZQV@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526,ko:K03676	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03110,ko03400	-	-	-	Glutaredoxin,Ribonuc_red_sm
k59_340479_2	1123518.ARWI01000001_gene1899	2.68e-45	164.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,45ZXG@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1131701_1	504487.JCM19302_922	4.25e-117	363.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_509754_1	1123326.JFBL01000004_gene2118	1.03e-52	185.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_509754_2	1565314.OA34_08140	7.89e-39	147.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_453853_1	688270.Celal_3914	1.36e-100	305.0	COG0668@1|root,COG0668@2|Bacteria,4NE4R@976|Bacteroidetes,1HXQS@117743|Flavobacteriia,1F8SP@104264|Cellulophaga	976|Bacteroidetes	M	Mechanosensitive ion channel	mscS2	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
k59_509758_1	1172190.M947_03940	9.04e-114	331.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2YMI2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_792665_1	1121931.AUHG01000010_gene74	7.31e-29	112.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_792665_2	1121931.AUHG01000010_gene75	8.01e-51	178.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_509765_2	90814.KL370892_gene2303	1.27e-134	385.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,460D9@72273|Thiotrichales	72273|Thiotrichales	Q	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_509765_3	1123518.ARWI01000001_gene1382	1.54e-28	110.0	COG1864@1|root,COG1864@2|Bacteria,1RADP@1224|Proteobacteria,1S30S@1236|Gammaproteobacteria,46156@72273|Thiotrichales	72273|Thiotrichales	F	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
k59_1357247_1	98439.AJLL01000051_gene3570	1.8e-08	57.8	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1JHSG@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_1357247_2	929558.SMGD1_1771	4.31e-28	102.0	2AK15@1|root,31AQQ@2|Bacteria,1Q5Z2@1224|Proteobacteria,43242@68525|delta/epsilon subdivisions,2YSUZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_114978_1	1484460.JSWG01000006_gene3014	1.75e-77	237.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1HWK9@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_114978_2	1137281.D778_00066	2.87e-124	355.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1HY4S@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_566735_1	1265313.HRUBRA_01637	3.44e-54	180.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1J8TX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_2101_1	42256.RradSPS_2889	7.27e-32	118.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
k59_2101_2	1123514.KB905902_gene200	4.31e-35	128.0	COG1073@1|root,COG1073@2|Bacteria,1R76C@1224|Proteobacteria,1RR34@1236|Gammaproteobacteria,461XK@72273|Thiotrichales	72273|Thiotrichales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
k59_1640177_1	745718.JADT01000005_gene15	5.14e-25	101.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_1640177_2	504487.JCM19302_1363	3.95e-106	316.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1HWXZ@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_962144_1	572480.Arnit_2763	9.95e-147	423.0	COG1538@1|root,COG1538@2|Bacteria,1Q066@1224|Proteobacteria,42RNJ@68525|delta/epsilon subdivisions,2YNZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_962144_2	1123326.JFBL01000009_gene874	0.00067	46.6	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,dCache_2
k59_58512_2	1469557.JSWF01000035_gene989	6.99e-46	161.0	COG3712@1|root,COG3712@2|Bacteria,4NH8I@976|Bacteroidetes,1HXP7@117743|Flavobacteriia	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
k59_453896_1	5039.XP_002620056.1	2.2e-21	98.2	COG1007@1|root,KOG4668@2759|Eukaryota,3940U@33154|Opisthokonta,3NXB5@4751|Fungi,3QSF9@4890|Ascomycota	4751|Fungi	C	NADH dehydrogenase subunit 2	nad2	-	1.6.5.3	ko:K03879	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k59_792677_1	1121912.AUHD01000001_gene2864	1.31e-48	169.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_792677_2	1121904.ARBP01000003_gene6275	1.54e-169	480.0	COG0451@1|root,COG0451@2|Bacteria,4NGJ6@976|Bacteroidetes,47NAH@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_792677_3	1347342.BN863_19860	2.58e-75	238.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k59_848657_1	1461577.CCMH01000004_gene1237	1.01e-59	199.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_848657_2	1144313.PMI10_00162	6.17e-68	214.0	COG1309@1|root,COG1309@2|Bacteria,4NJ2Z@976|Bacteroidetes,1IJ22@117743|Flavobacteriia,2P0I4@237|Flavobacterium	976|Bacteroidetes	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
k59_509787_1	1123228.AUIH01000006_gene2253	1.29e-113	335.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1XHV7@135619|Oceanospirillales	135619|Oceanospirillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_1357270_1	1406840.Q763_09660	1.5e-19	84.3	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HZ24@117743|Flavobacteriia,2NT6J@237|Flavobacterium	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1357270_2	1406840.Q763_09655	1.55e-166	466.0	COG0464@1|root,COG0464@2|Bacteria,4NH44@976|Bacteroidetes,1HXKG@117743|Flavobacteriia,2NVR6@237|Flavobacterium	976|Bacteroidetes	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_1640197_1	411154.GFO_3416	3.45e-102	313.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_623382_1	90814.KL370891_gene850	5.11e-48	160.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,46104@72273|Thiotrichales	72273|Thiotrichales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_227951_1	90814.KL370892_gene2033	1.05e-147	424.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,46071@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_227951_2	243274.THEMA_05480	3.63e-57	191.0	COG2730@1|root,COG2730@2|Bacteria,2GDQI@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
k59_623387_1	929558.SMGD1_1722	4.32e-138	404.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2YMHI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1303268_1	1380600.AUYN01000007_gene3071	5.52e-234	672.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1HXND@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
k59_738128_1	1122137.AQXF01000002_gene451	3.74e-06	47.4	COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,2UCHN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_738128_2	864051.BurJ1DRAFT_4857	3.22e-85	261.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2VJCK@28216|Betaproteobacteria,1KJ27@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
k59_342165_1	1201293.AKXQ01000005_gene91	0.000453	42.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
k59_173461_1	102129.Lepto7375DRAFT_6332	9.88e-78	244.0	COG4310@1|root,COG4310@2|Bacteria,1G39N@1117|Cyanobacteria,1H9B5@1150|Oscillatoriales	1117|Cyanobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
k59_681886_1	1123514.KB905899_gene546	1.26e-120	362.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,460E6@72273|Thiotrichales	72273|Thiotrichales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_681886_2	1123518.ARWI01000001_gene2128	3.99e-69	209.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k59_681886_3	1123518.ARWI01000001_gene2129	1.66e-35	125.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,460DN@72273|Thiotrichales	72273|Thiotrichales	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	-	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
k59_116736_2	1172190.M947_08890	3.42e-102	306.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,43D3D@68525|delta/epsilon subdivisions,2YTG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_794682_1	1380600.AUYN01000009_gene1197	4.97e-149	453.0	COG0460@1|root,COG0527@1|root,COG2021@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,COG2021@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Abhydrolase_1,Homoserine_dh,NAD_binding_3
k59_342172_1	90814.KL370891_gene870	9.83e-156	466.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,Response_reg,dCache_1
k59_342172_2	1123514.KB905899_gene1348	1.02e-79	250.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,45ZUI@72273|Thiotrichales	72273|Thiotrichales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_511699_1	1121931.AUHG01000018_gene1417	1.41e-102	307.0	COG0589@1|root,COG0589@2|Bacteria,4NF5D@976|Bacteroidetes,1HZH6@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_399343_1	387092.NIS_1048	3.87e-48	156.0	COG1393@1|root,COG1393@2|Bacteria,1PPAE@1224|Proteobacteria,42SIG@68525|delta/epsilon subdivisions,2YSZ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
k59_399343_2	929558.SMGD1_2437	1.41e-15	75.9	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2YMY9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1585574_2	153721.MYP_4558	1.9e-20	88.6	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,47M82@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_1642166_1	1121887.AUDK01000017_gene39	2.76e-151	442.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1HYUH@117743|Flavobacteriia,2NUAJ@237|Flavobacterium	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
k59_1642166_2	1202532.FF52_16933	1.08e-90	271.0	COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes,1HZD8@117743|Flavobacteriia,2NSVI@237|Flavobacterium	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_568513_1	290398.Csal_2052	7.94e-83	261.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1XHK2@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_1642169_1	700598.Niako_2737	1.02e-18	91.7	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1J0JM@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_455916_1	1121931.AUHG01000016_gene984	5.15e-144	414.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1HX17@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_1245912_1	1355374.JARU01000015_gene1079	4.89e-09	55.8	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2YMVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1245912_2	563040.Saut_1471	8.29e-139	410.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_116792_1	398720.MED217_17630	3.17e-17	74.3	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,1I54J@117743|Flavobacteriia,2XJK5@283735|Leeuwenhoekiella	976|Bacteroidetes	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_116792_2	1380600.AUYN01000007_gene3301	0.0	1224.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1HXDK@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_794755_1	62928.azo2623	1.57e-81	243.0	COG0457@1|root,COG0457@2|Bacteria,1RKIY@1224|Proteobacteria,2W3MG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SMI1-KNR4 cell-wall	-	-	-	-	-	-	-	-	-	-	-	-	SUKH_6
k59_794755_2	323261.Noc_1136	3.01e-24	99.0	28T9V@1|root,2ZFIG@2|Bacteria,1P7PF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3882_1	1380600.AUYN01000009_gene2127	7.19e-111	323.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1HX3V@117743|Flavobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
k59_187931_1	387093.SUN_0542	4.67e-107	325.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria,1MUGA@1224|Proteobacteria,42NI0@68525|delta/epsilon subdivisions,2YNKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	ATP citrate synthase	-	-	2.3.3.8	ko:K15230	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,Ligase_CoA
k59_244413_2	411154.GFO_1768	7.45e-124	357.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
k59_356009_1	1380600.AUYN01000001_gene2590	2.76e-183	529.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1HX0Y@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k59_975013_1	391603.FBALC1_00592	2.99e-40	142.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1HYD7@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_975013_2	1178825.ALIH01000013_gene483	3.94e-47	154.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_1317981_1	1121931.AUHG01000010_gene784	1.15e-114	333.0	28HKZ@1|root,2Z7VP@2|Bacteria,4NFGM@976|Bacteroidetes,1HWRW@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3050
k59_1089947_1	1336233.JAEH01000004_gene1436	1.77e-56	183.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,2QAA3@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_1486739_1	1123228.AUIH01000006_gene2246	1.42e-86	271.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XIFS@135619|Oceanospirillales	135619|Oceanospirillales	CI	Oxaloacetate decarboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_1486741_1	1163617.SCD_n01716	7.51e-115	344.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_1317985_1	1123514.KB905900_gene2219	6.56e-75	225.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,460SW@72273|Thiotrichales	72273|Thiotrichales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_1486755_1	1123228.AUIH01000006_gene2268	9.91e-13	65.5	COG3981@1|root,COG3981@2|Bacteria,1QRSS@1224|Proteobacteria,1STS4@1236|Gammaproteobacteria,1XQCI@135619|Oceanospirillales	135619|Oceanospirillales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_1486755_2	765914.ThisiDRAFT_0322	8.11e-49	165.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_809117_1	563040.Saut_1259	4.31e-135	386.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2YNB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_130444_1	385682.AFSL01000069_gene1470	1.63e-08	57.8	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,2FQJ2@200643|Bacteroidia,3XJBY@558415|Marinilabiliaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_130444_2	1137281.D778_02681	5.2e-24	95.5	COG4232@1|root,COG4232@2|Bacteria,4NPWP@976|Bacteroidetes,1I23K@117743|Flavobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_1656335_1	1121931.AUHG01000011_gene2152	4.55e-36	124.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1I2VB@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_1656335_2	411154.GFO_2227	1.32e-140	416.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia	976|Bacteroidetes	EM	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
k59_639629_1	411154.GFO_3369	1.99e-58	192.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_639629_2	411154.GFO_3368	2.16e-42	145.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_16945_1	1492738.FEM21_10270	3.16e-48	172.0	COG3866@1|root,COG4677@1|root,COG4935@1|root,COG5263@1|root,COG5492@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,COG4935@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,4NHZ1@976|Bacteroidetes,1IJTK@117743|Flavobacteriia,2NTRH@237|Flavobacterium	976|Bacteroidetes	G	pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
k59_1769537_1	1178825.ALIH01000004_gene2966	6.37e-155	445.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
k59_1712844_1	1232410.KI421426_gene1408	6.82e-28	105.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,43SIF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_1712844_2	1232410.KI421426_gene1407	7.96e-54	177.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43S7Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Formyl transferase, C-terminal domain	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_1600334_1	1123367.C666_01810	5.43e-50	183.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,2KVBE@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_582833_1	1178825.ALIH01000008_gene767	1.32e-31	122.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,1I2VC@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8
k59_809192_1	504487.JCM19302_1367	1.27e-63	202.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_1486824_1	411154.GFO_2116	8.82e-75	237.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_75065_1	1392490.JHZX01000001_gene1066	8.09e-20	88.2	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_75065_2	1235803.C825_03346	2.62e-24	100.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,2FNQ4@200643|Bacteroidia,22XTP@171551|Porphyromonadaceae	976|Bacteroidetes	E	synthase small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_75065_3	1341155.FSS13T_08420	5.48e-07	51.2	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia,2NSKX@237|Flavobacterium	976|Bacteroidetes	E	Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1260184_1	1121904.ARBP01000019_gene2748	0.000476	44.3	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,CHU_C,PKD
k59_1260184_2	933262.AXAM01000061_gene1668	3.79e-06	52.0	COG4970@1|root,COG4970@2|Bacteria,1Q0DU@1224|Proteobacteria,42W7A@68525|delta/epsilon subdivisions,2WS6U@28221|Deltaproteobacteria,2MKVN@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k59_1769579_1	1232410.KI421413_gene534	5.48e-74	243.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZD5@68525|delta/epsilon subdivisions,2WUEK@28221|Deltaproteobacteria,43TFW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, HAMP and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,sCache_3_2
k59_696871_1	929558.SMGD1_1840	1.19e-114	332.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2YMSK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_75089_2	326298.Suden_1090	9.85e-91	273.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2YNX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_1034620_1	1123228.AUIH01000002_gene1426	2.85e-124	364.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XH6X@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_244561_1	1172190.M947_09500	3.53e-55	181.0	COG0745@1|root,COG0745@2|Bacteria,1QGBK@1224|Proteobacteria,42T0C@68525|delta/epsilon subdivisions,2YPNB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_356141_2	1168067.JAGP01000001_gene1821	3.67e-254	696.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,1RY6Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates	amiE	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_356141_3	1168067.JAGP01000001_gene1723	3.51e-104	306.0	COG2215@1|root,COG2215@2|Bacteria	2|Bacteria	O	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_356141_4	1168067.JAGP01000001_gene1724	2.3e-91	270.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,4601H@72273|Thiotrichales	72273|Thiotrichales	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
k59_975124_1	1232410.KI421416_gene2648	1.25e-25	96.7	COG3162@1|root,COG3162@2|Bacteria,1NB5T@1224|Proteobacteria,42VP8@68525|delta/epsilon subdivisions,2WSCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_472749_1	1123228.AUIH01000005_gene657	6.1e-89	270.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XHW1@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_1658583_1	1121931.AUHG01000011_gene2427	1.19e-134	395.0	COG1215@1|root,COG1215@2|Bacteria,4NMZS@976|Bacteroidetes,1I7QP@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3
k59_358136_1	1249975.JQLP01000001_gene3212	9.14e-85	262.0	COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1HZ88@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
k59_641904_1	1137281.D778_00299	1.21e-210	614.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_1262480_1	1237149.C900_00732	1.93e-20	89.4	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,47KR6@768503|Cytophagia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1262480_2	1120965.AUBV01000005_gene1757	1.13e-06	53.1	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,47JP5@768503|Cytophagia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase N-terminal domain subunit	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_641917_1	1178825.ALIH01000001_gene2685	5.96e-74	228.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
k59_641917_2	504487.JCM19302_864	3.3e-15	72.4	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_1431642_2	1123518.ARWI01000001_gene2211	1.76e-84	254.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S3RF@1236|Gammaproteobacteria,461H0@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Cytochrome b(N-terminal) b6 petB	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
k59_1431642_3	292415.Tbd_1279	2.05e-25	102.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,2VPGW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
k59_1544072_1	1321773.HMPREF9069_01851	4.64e-24	115.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CUGG@84998|Coriobacteriia	84998|Coriobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1715187_1	1336233.JAEH01000043_gene3874	1.73e-119	371.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QA13@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrF	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1544084_1	572480.Arnit_2416	1.1e-107	316.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2YMG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_246798_1	945713.IALB_2269	1.12e-65	209.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1092192_1	1406840.Q763_09590	1.82e-64	208.0	COG3843@1|root,COG3843@2|Bacteria,4NG66@976|Bacteroidetes,1HZ44@117743|Flavobacteriia,2NSC5@237|Flavobacterium	976|Bacteroidetes	U	Relaxase	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
k59_1092192_2	1406840.Q763_09585	1.25e-234	659.0	COG3505@1|root,COG3505@2|Bacteria,4NFHI@976|Bacteroidetes,1HWU1@117743|Flavobacteriia,2NTE7@237|Flavobacterium	976|Bacteroidetes	U	Conjugal transfer protein TraG	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C,TrwB_AAD_bind,YWFCY
k59_472791_1	411154.GFO_3583	1.7e-117	355.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_190238_1	1380600.AUYN01000007_gene3063	3.3e-123	364.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1602676_1	1122197.ATWI01000011_gene460	2.85e-07	58.9	COG0433@1|root,COG0433@2|Bacteria,1QTVP@1224|Proteobacteria,1T1IQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Zonular occludens toxin (Zot)	-	-	-	ko:K10954	ko05110,map05110	-	-	-	ko00000,ko00001,ko02042	-	-	-	Zot
k59_1092204_1	1565129.JSFF01000034_gene1487	6.17e-14	70.5	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,2Q9I8@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_1092204_2	323850.Shew_1379	4.76e-72	226.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,2Q96F@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_77432_1	714943.Mucpa_1038	1.72e-41	148.0	COG1277@1|root,COG1277@2|Bacteria,4NGAT@976|Bacteroidetes,1IPNS@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
k59_77432_2	1122621.ATZA01000001_gene2042	3.05e-92	281.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1IQRY@117747|Sphingobacteriia	976|Bacteroidetes	V	PFAM ABC transporter	yxlF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1658644_1	1177181.T9A_00691	4.3e-61	200.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XIGF@135619|Oceanospirillales	135619|Oceanospirillales	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1658644_2	1415778.JQMM01000001_gene111	5.75e-19	85.9	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1J55M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase domain	gltB	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1036887_1	1190606.AJYG01000051_gene1253	1.21e-37	141.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XTT6@135623|Vibrionales	135623|Vibrionales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_811672_1	1123517.JOMR01000001_gene1764	6.96e-26	106.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,45ZWT@72273|Thiotrichales	72273|Thiotrichales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_811672_2	1123518.ARWI01000001_gene2119	5.7e-57	181.0	COG4701@1|root,COG4701@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF721)	Y3619	-	-	-	-	-	-	-	-	-	-	-	DUF721
k59_811672_3	930169.B5T_03482	4.88e-14	71.2	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1XIMD@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k59_753789_1	1392489.JPOL01000002_gene2228	1.85e-119	357.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2XIW1@283735|Leeuwenhoekiella	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_753789_2	1249975.JQLP01000005_gene521	6.83e-259	739.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia,2P6AS@244698|Gillisia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_415645_1	1123518.ARWI01000001_gene1843	5.93e-65	202.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,460IK@72273|Thiotrichales	72273|Thiotrichales	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
k59_77452_1	1121931.AUHG01000010_gene547	3.88e-56	177.0	COG0454@1|root,COG0456@2|Bacteria,4NM68@976|Bacteroidetes,1I1DY@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_77452_2	411154.GFO_3520	9.01e-90	264.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,1I258@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_699191_1	1380600.AUYN01000006_gene295	7.44e-125	376.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_77453_2	1538644.KO02_02015	4.34e-141	416.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,1IQX6@117747|Sphingobacteriia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
k59_1374824_1	6412.HelroP92462	4.85e-08	50.4	2E3A4@1|root,2SADZ@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_302938_1	391603.FBALC1_06138	1.55e-65	222.0	COG1629@1|root,COG4771@2|Bacteria,4NICF@976|Bacteroidetes,1I0D3@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1544142_1	1123518.ARWI01000001_gene2058	4.73e-118	345.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,461ZR@72273|Thiotrichales	72273|Thiotrichales	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
k59_358238_1	273121.WS1205	7.62e-52	189.0	COG2199@1|root,COG2202@1|root,COG4564@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4564@2|Bacteria,1QYD2@1224|Proteobacteria,42PVI@68525|delta/epsilon subdivisions,2YNV3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_246884_1	90814.KL370891_gene490	4.37e-112	331.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,45ZQI@72273|Thiotrichales	72273|Thiotrichales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_77487_1	509635.N824_07325	2.62e-25	96.7	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_35225_1	1537917.JU82_02985	5.18e-45	153.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42PA1@68525|delta/epsilon subdivisions,2YNMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_319818_1	87626.PTD2_19290	8.5e-64	199.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,2Q0BC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765	Fer2_3,Fer4_17,Fer4_8
k59_149224_1	929558.SMGD1_0630	9.81e-116	346.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions,2YNM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,sCache_like
k59_149224_2	929558.SMGD1_0629	2.4e-11	59.3	COG2932@1|root,COG2932@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
k59_1788901_1	1178825.ALIH01000003_gene2252	2.18e-59	186.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1I23R@117743|Flavobacteriia	976|Bacteroidetes	S	(GNAT) family	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k59_1788901_2	1380600.AUYN01000007_gene3146	7.38e-73	238.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1HZKN@117743|Flavobacteriia	976|Bacteroidetes	DZ	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LRR_4
k59_1731765_1	373903.Hore_11330	6.6e-34	133.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,3WAG0@53433|Halanaerobiales	186801|Clostridia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_206973_1	929558.SMGD1_1206	5.44e-130	375.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2YMNC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_1731773_1	243231.GSU2813	2.99e-94	285.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2WMZF@28221|Deltaproteobacteria,43TFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	2 heme-binding sites	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_1109139_1	62928.azo3137	1.22e-90	276.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria,2KUGY@206389|Rhodocyclales	206389|Rhodocyclales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1212078_1	1380600.AUYN01000007_gene3260	8.75e-112	338.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_1166018_2	211586.SO_0754	4.72e-13	67.4	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,2QAGY@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter transmembrane region	atmA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1560904_1	1121931.AUHG01000012_gene2626	3.47e-39	137.0	COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,1I1FX@117743|Flavobacteriia	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
k59_1560904_2	1121931.AUHG01000012_gene2627	1.14e-24	101.0	COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes,1HXM0@117743|Flavobacteriia	976|Bacteroidetes	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_1052306_1	1191523.MROS_1120	2.35e-17	87.8	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	Z012_05430	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_149268_1	1380600.AUYN01000007_gene3273	2.76e-14	70.5	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_1731805_1	317025.Tcr_1495	5.14e-59	191.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,461SY@72273|Thiotrichales	72273|Thiotrichales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_1731805_2	1123514.KB905899_gene1485	5.05e-245	684.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,463P7@72273|Thiotrichales	72273|Thiotrichales	HP	THUMP	-	-	-	-	-	-	-	-	-	-	-	-	THUMP,ThiI
k59_149306_1	62928.azo3409	3.73e-05	42.4	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,2KXD6@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_149306_2	62928.azo3408	1.9e-50	160.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,2KX1P@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_263786_1	1172190.M947_04865	1.92e-12	66.2	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,42RPB@68525|delta/epsilon subdivisions,2YP5G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_321918_1	1565314.OA34_08780	6.98e-90	284.0	COG1538@1|root,COG1538@2|Bacteria,1R860@1224|Proteobacteria,42R4V@68525|delta/epsilon subdivisions,2YNVE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_37334_1	563040.Saut_1834	1.36e-108	313.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2YMUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_37334_2	1172190.M947_04135	2.02e-78	234.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42SCR@68525|delta/epsilon subdivisions,2YP9N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_96139_1	945713.IALB_2904	3.83e-25	107.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2,PPC,Peptidase_S51
k59_719689_2	411154.GFO_0749	2.2e-58	191.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1HXB7@117743|Flavobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1053986_1	497321.C664_18182	3.5e-57	182.0	COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,2VSD2@28216|Betaproteobacteria,2KWYK@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
k59_1053986_2	497321.C664_18177	2.76e-15	72.8	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,2VH63@28216|Betaproteobacteria,2KW32@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_602059_1	748658.KB907314_gene171	3.12e-37	137.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_602059_2	1269813.ATUL01000017_gene2553	1.81e-19	83.2	COG2142@1|root,COG2142@2|Bacteria,1RH1K@1224|Proteobacteria,1S7GT@1236|Gammaproteobacteria,1WYKS@135613|Chromatiales	135613|Chromatiales	C	Succinate dehydrogenase hydrophobic membrane anchor	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_37350_1	102125.Xen7305DRAFT_00020060	1.19e-09	70.5	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
k59_1450130_1	425104.Ssed_4105	2.64e-139	400.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,2Q9MX@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_37362_1	1168034.FH5T_13230	3.99e-183	516.0	COG3940@1|root,COG3940@2|Bacteria,4PKWP@976|Bacteroidetes,2G06I@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
k59_37362_2	657309.BXY_17850	3.53e-08	56.2	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,2FR92@200643|Bacteroidia,4AP2V@815|Bacteroidaceae	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
k59_719720_1	1249480.B649_06950	2.12e-39	134.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_719720_2	563040.Saut_2085	6.88e-13	68.2	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	iscU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_434687_1	572480.Arnit_2687	1.14e-113	331.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2YMZR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_37365_1	641524.ADICYQ_5370	1.62e-09	60.1	COG0642@1|root,COG2205@2|Bacteria,4NG6V@976|Bacteroidetes,47NKX@768503|Cytophagia	976|Bacteroidetes	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
k59_37365_2	1121931.AUHG01000019_gene2963	2.87e-28	112.0	COG0642@1|root,COG2205@2|Bacteria,4NG6V@976|Bacteroidetes,1I1HR@117743|Flavobacteriia	976|Bacteroidetes	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
k59_719725_1	62928.azo0957	5.45e-86	272.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_831260_1	1046627.BZARG_2311	4.61e-18	82.4	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_831260_2	1380600.AUYN01000001_gene2489	9.52e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1HYAN@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1508805_1	1168067.JAGP01000001_gene766	1.27e-111	333.0	COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,1RZPI@1236|Gammaproteobacteria,4628X@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_1508805_2	1123518.ARWI01000001_gene1859	3.28e-49	174.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,4614F@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_9
k59_1621941_2	686340.Metal_0566	2.25e-21	94.0	COG1106@1|root,COG1106@2|Bacteria,1N694@1224|Proteobacteria,1SB7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k59_1677536_1	90814.KL370891_gene1702	1.11e-38	139.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,460K0@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k59_1677536_2	1123518.ARWI01000001_gene1939	2.44e-09	57.8	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,45ZMN@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_96203_1	411154.GFO_2999	2.73e-74	249.0	COG0784@1|root,COG1520@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1520@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NK8Q@976|Bacteroidetes,1IMWE@117743|Flavobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HTH_18,Reg_prop,SpoIIE,Y_Y_Y
k59_96210_1	83406.HDN1F_01240	3.26e-63	207.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_831279_1	1380600.AUYN01000009_gene1934	8.22e-77	238.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1621964_2	1137281.D778_00776	3.15e-82	244.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,1I1II@117743|Flavobacteriia	976|Bacteroidetes	J	Translation initiation inhibitor, yjgF family	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
k59_1621964_3	1178825.ALIH01000008_gene727	5.97e-57	190.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia	976|Bacteroidetes	CH	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_1281398_1	1123514.KB905899_gene1053	1.6e-34	125.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,4610T@72273|Thiotrichales	72273|Thiotrichales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_1281398_2	1123514.KB905899_gene1052	1.15e-37	137.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,46067@72273|Thiotrichales	72273|Thiotrichales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_1054065_1	1123234.AUKI01000021_gene942	2.34e-63	218.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1393776_2	1121931.AUHG01000011_gene1689	6.73e-86	253.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1I18F@117743|Flavobacteriia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_376838_1	1121931.AUHG01000010_gene639	5.98e-87	269.0	COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,1HY19@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
k59_434779_1	1249627.D779_3943	4.1e-172	497.0	COG3316@1|root,COG3316@2|Bacteria,1QE29@1224|Proteobacteria,1T5ZZ@1236|Gammaproteobacteria,1X2WN@135613|Chromatiales	135613|Chromatiales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_1340203_1	1121931.AUHG01000010_gene705	3.16e-148	430.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,1HZX1@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_1168197_1	319225.Plut_0436	2.52e-25	106.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_491374_1	1565129.JSFF01000022_gene1399	9.55e-84	257.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,2Q9SD@267890|Shewanellaceae	1236|Gammaproteobacteria	S	AI-2E family transporter	tqsA	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
k59_322085_1	62928.azo0747	4.13e-89	275.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,2KX0M@206389|Rhodocyclales	206389|Rhodocyclales	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
k59_209274_1	944547.ABLL_1414	7.18e-11	61.2	COG0745@1|root,COG0745@2|Bacteria,1N8XN@1224|Proteobacteria,42WCI@68525|delta/epsilon subdivisions,2YRPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_209274_2	944547.ABLL_1415	4.85e-99	296.0	2B2M3@1|root,31V6H@2|Bacteria,1QT2M@1224|Proteobacteria,42ZNF@68525|delta/epsilon subdivisions,2YRQ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_209274_3	1123326.JFBL01000001_gene1232	4.5e-09	56.2	COG0745@1|root,COG0745@2|Bacteria,1N8XN@1224|Proteobacteria,42WCI@68525|delta/epsilon subdivisions,2YRPH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_886370_1	1123517.JOMR01000001_gene1390	2.08e-153	441.0	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,1RNU6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_1340238_1	1392490.JHZX01000001_gene584	3.47e-65	202.0	COG0671@1|root,COG0671@2|Bacteria,4NP0U@976|Bacteroidetes,1I0CZ@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_1340238_2	1392489.JPOL01000002_gene3050	3.43e-31	114.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,1IISJ@117743|Flavobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
k59_376911_1	563040.Saut_0686	1.81e-151	448.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1733976_1	572480.Arnit_2589	3.35e-75	225.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2YP65@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_37533_1	1178825.ALIH01000003_gene2179	2.35e-36	132.0	COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1HXK4@117743|Flavobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor RskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
k59_37533_2	1121912.AUHD01000001_gene2702	7.8e-98	287.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1I0DR@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_37533_3	398720.MED217_07596	1.1e-09	57.0	COG2032@1|root,COG2032@2|Bacteria,4NM88@976|Bacteroidetes,1I17T@117743|Flavobacteriia,2XJ5K@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Copper/zinc superoxide dismutase (SODC)	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
k59_491417_1	1007104.SUS17_2726	4.03e-70	239.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K2G6@204457|Sphingomonadales	204457|Sphingomonadales	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_1168248_1	425104.Ssed_1346	1.67e-22	89.0	COG1544@1|root,COG1544@2|Bacteria,1RE99@1224|Proteobacteria,1S4IT@1236|Gammaproteobacteria,2QBZZ@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	rpoX	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_322133_1	572480.Arnit_1304	2.49e-76	239.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2YNM1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_1508980_1	1168034.FH5T_06515	9.41e-36	131.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
k59_265507_1	572480.Arnit_1652	2.93e-104	308.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2YN78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
k59_1111463_1	187272.Mlg_0116	4.51e-89	275.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,1RQQA@1236|Gammaproteobacteria,1X0G6@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_1393919_1	1121931.AUHG01000010_gene780	1.76e-39	140.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_1393919_2	655815.ZPR_0506	3.64e-44	144.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1I3YF@117743|Flavobacteriia	976|Bacteroidetes	O	Nitrogen fixation protein NifU	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_1563222_1	572480.Arnit_1296	1.74e-74	231.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,42RGN@68525|delta/epsilon subdivisions,2YPAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
k59_265526_1	317025.Tcr_2151	6.35e-106	323.0	COG0004@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2199@2|Bacteria,1NR9F@1224|Proteobacteria,1T3XB@1236|Gammaproteobacteria,463UW@72273|Thiotrichales	72273|Thiotrichales	U	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1734053_1	998674.ATTE01000001_gene3872	8.55e-57	186.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_546162_1	1565129.JSFF01000001_gene848	6.23e-107	322.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,2Q8IX@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1168320_1	411154.GFO_1599	5.83e-121	352.0	COG2116@1|root,COG2116@2|Bacteria,4NFNU@976|Bacteroidetes,1HZ12@117743|Flavobacteriia	976|Bacteroidetes	P	Formate/nitrite transporter	-	-	-	ko:K21990,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2,1.A.16.4	-	-	Form_Nir_trans
k59_558356_1	1123514.KB905899_gene1714	1.65e-111	331.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,460FJ@72273|Thiotrichales	72273|Thiotrichales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k59_558356_2	317025.Tcr_0389	1.73e-23	97.1	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_786106_1	1178825.ALIH01000012_gene1825	6.19e-66	223.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
k59_674147_1	563040.Saut_0536	6.73e-78	247.0	COG4773@1|root,COG4773@2|Bacteria,1QZMX@1224|Proteobacteria,42SA0@68525|delta/epsilon subdivisions,2YPCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1294267_1	945713.IALB_0720	3.35e-70	236.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_558376_1	1121931.AUHG01000011_gene1893	1.83e-51	166.0	2E6H5@1|root,3314C@2|Bacteria,4NVB7@976|Bacteroidetes,1I51P@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
k59_1007201_1	572480.Arnit_2278	1.96e-111	330.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,42M4U@68525|delta/epsilon subdivisions,2YN58@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	permease	-	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
k59_221806_1	929558.SMGD1_1851	1.07e-43	154.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2YMTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_224197_1	717773.Thicy_0292	1.14e-11	64.3	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,4611Q@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_224197_2	1123514.KB905900_gene2139	9.58e-46	163.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,460GF@72273|Thiotrichales	72273|Thiotrichales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_111978_1	1123518.ARWI01000001_gene1264	1.49e-181	509.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,45ZPX@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_111978_2	1123514.KB905899_gene2019	2.34e-38	135.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales	72273|Thiotrichales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_224200_1	1123518.ARWI01000001_gene2419	3.02e-108	327.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_788614_1	1189619.pgond44_06620	1.93e-16	80.9	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,4C2GT@83612|Psychroflexus	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
k59_788614_2	1249975.JQLP01000001_gene3490	4.67e-10	58.9	COG0398@1|root,COG0398@2|Bacteria,4NFIC@976|Bacteroidetes,1HXVB@117743|Flavobacteriia,2P5CA@244698|Gillisia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_1229327_2	563040.Saut_0556	1.43e-84	268.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YR82@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1406993_1	90814.KL370891_gene911	4.4e-78	254.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,461R1@72273|Thiotrichales	72273|Thiotrichales	O	Belongs to the peptidase S16 family	-	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_843225_1	929558.SMGD1_1155	9.23e-47	151.0	COG2921@1|root,COG2921@2|Bacteria,1Q61Q@1224|Proteobacteria,42WSH@68525|delta/epsilon subdivisions,2YQB4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0250 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
k59_843225_2	929558.SMGD1_1156	1.97e-29	115.0	2AIMJ@1|root,3193W@2|Bacteria,1Q1QU@1224|Proteobacteria,42U73@68525|delta/epsilon subdivisions,2YSXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1126948_1	1392490.JHZX01000001_gene1634	2.24e-126	372.0	COG1541@1|root,COG1541@2|Bacteria,4NFFT@976|Bacteroidetes,1HZKR@117743|Flavobacteriia	976|Bacteroidetes	H	COG1541 Coenzyme F390 synthetase	capK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
k59_1183671_1	1121931.AUHG01000011_gene1632	1.21e-103	315.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia	976|Bacteroidetes	S	Gliding motility protein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_788637_1	948106.AWZT01000040_gene3841	4.52e-90	283.0	COG3867@1|root,COG3867@2|Bacteria,1R33X@1224|Proteobacteria,2VP1Z@28216|Betaproteobacteria,1K0J9@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53
k59_676691_1	1178825.ALIH01000007_gene1729	2.49e-111	327.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_900576_1	411154.GFO_2269	7.27e-38	134.0	28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,1I1PA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_900576_2	1121931.AUHG01000011_gene2112	2e-97	284.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_900576_3	411154.GFO_2271	4.21e-16	77.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1HXTQ@117743|Flavobacteriia	976|Bacteroidetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_843239_1	1121931.AUHG01000012_gene2875	9.65e-118	366.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
k59_1464703_1	867900.Celly_2211	3.45e-141	410.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia,1F7TV@104264|Cellulophaga	976|Bacteroidetes	H	COGs COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1631535_1	572480.Arnit_1824	2.08e-102	306.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2YN96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1631535_2	572480.Arnit_1823	2e-08	55.1	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2YN0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_1524545_1	1469557.JSWF01000046_gene157	1.4e-65	205.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
k59_1524545_2	1046627.BZARG_535	1.92e-158	448.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1HWSY@117743|Flavobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_337636_1	1380600.AUYN01000009_gene2169	4.95e-149	431.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_843269_1	983544.Lacal_1864	1.28e-57	188.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1HX8P@117743|Flavobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
k59_843269_2	1137281.D778_00586	1.25e-35	125.0	2CC77@1|root,32S0M@2|Bacteria,4NS9F@976|Bacteroidetes,1I3Y8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
k59_616689_1	225849.swp_2703	4.38e-76	236.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S2WF@1236|Gammaproteobacteria,2QA2H@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k59_166030_1	1385517.N800_08915	1.07e-49	160.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_616690_1	572480.Arnit_1582	2.15e-103	310.0	2C8CV@1|root,2Z8NV@2|Bacteria,1MWPM@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3095)	MA20_06625	-	-	-	-	-	-	-	-	-	-	-	DUF3095
k59_1524582_1	62928.azo1256	2.98e-81	262.0	COG0515@1|root,COG1639@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria,2KUM0@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HDOD,Pkinase
k59_1183735_1	326298.Suden_0492	7.12e-20	89.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_1183735_3	1172190.M947_02985	1.44e-65	202.0	COG1331@1|root,COG1331@2|Bacteria,1N55I@1224|Proteobacteria,42VTZ@68525|delta/epsilon subdivisions,2YQJ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k59_1183735_4	563040.Saut_1625	4.85e-36	133.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2YN91@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1297041_1	563040.Saut_1838	1.19e-105	311.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2YMF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_1009897_1	929558.SMGD1_0790	4.6e-34	121.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42T4D@68525|delta/epsilon subdivisions,2YPHE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_1009897_2	929558.SMGD1_0789	1.7e-101	301.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2YMRZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_506641_1	177439.DP2492	3.84e-69	218.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria,2MIBM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k59_616705_1	929558.SMGD1_0921	1.16e-132	393.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2YMEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1693149_1	1232683.ADIMK_1122	7.77e-57	201.0	COG0834@1|root,COG2202@1|root,COG2208@1|root,COG3829@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GerE,HATPase_c,MASE1,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SBP_bac_3
k59_788723_1	118005.AWNK01000010_gene294	3.13e-07	57.8	COG4753@1|root,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
k59_1229439_1	1123367.C666_08990	5.1e-62	198.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,2KUA5@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_1229439_2	62928.azo3960	1.79e-12	65.5	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,2KUSK@206389|Rhodocyclales	206389|Rhodocyclales	S	Stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_1464800_1	313590.MED134_07556	5.24e-84	267.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1HY1A@117743|Flavobacteriia,37EVR@326319|Dokdonia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
k59_51716_1	709032.Sulku_2404	2.63e-56	186.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,42N2Z@68525|delta/epsilon subdivisions,2YN19@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	CDP-glucose 4,6-dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_51716_2	709032.Sulku_2405	8.1e-46	151.0	COG1898@1|root,COG1898@2|Bacteria,1RKXH@1224|Proteobacteria,43B9W@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_1407073_2	1380600.AUYN01000006_gene539	1.44e-174	494.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
k59_788732_1	563040.Saut_0315	5.03e-116	335.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2YMN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_788732_2	1249480.B649_10720	6.82e-82	244.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2YNWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_788732_3	326298.Suden_0348	4.26e-18	79.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2YMJK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_1069253_1	1198114.AciX9_1229	1.07e-30	125.0	28M68@1|root,2ZAJX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1577540_1	85643.Tmz1t_2548	1.77e-149	436.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KV73@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_166091_1	1121931.AUHG01000010_gene852	2.91e-104	310.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k59_337732_1	313590.MED134_08641	1.13e-05	44.3	2ACKV@1|root,31279@2|Bacteria,4PH2M@976|Bacteroidetes,1IFTJ@117743|Flavobacteriia,37FTY@326319|Dokdonia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_337732_2	867900.Celly_3231	8.2e-67	213.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1I285@117743|Flavobacteriia,1F80A@104264|Cellulophaga	976|Bacteroidetes	K	SMART Helix-turn-helix, AraC type, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_278456_1	1121931.AUHG01000015_gene1218	1.18e-27	105.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes,1I1D2@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_278456_2	1121931.AUHG01000015_gene1219	1.35e-37	132.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1I181@117743|Flavobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_1229488_1	225849.swp_3554	1.14e-105	320.0	COG2070@1|root,COG2070@2|Bacteria,1MWMI@1224|Proteobacteria,1RYC2@1236|Gammaproteobacteria,2QA98@267890|Shewanellaceae	1236|Gammaproteobacteria	S	2-nitropropane dioxygenase	pfaD	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3,NMO
k59_166109_1	1123514.KB905899_gene1925	9.75e-07	50.1	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,46000@72273|Thiotrichales	72273|Thiotrichales	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_166109_2	1123514.KB905899_gene1926	2.32e-70	226.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales	72273|Thiotrichales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_616770_1	90813.JQMT01000001_gene2158	6.25e-15	69.7	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,460RK@72273|Thiotrichales	72273|Thiotrichales	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_112183_1	1469557.JSWF01000035_gene932	2.41e-110	338.0	COG1629@1|root,COG4771@2|Bacteria,4NFKZ@976|Bacteroidetes,1HY23@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_953228_1	1353528.DT23_10475	5.31e-51	165.0	COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2TT3H@28211|Alphaproteobacteria,2XN0G@285107|Thioclava	28211|Alphaproteobacteria	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
k59_953228_2	1353528.DT23_10480	4.48e-46	150.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,2XN9Y@285107|Thioclava	28211|Alphaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
k59_561032_1	1123234.AUKI01000017_gene2660	3.17e-125	388.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_392720_1	1380600.AUYN01000007_gene3258	1.29e-99	298.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
k59_1009999_1	1121931.AUHG01000011_gene2388	9.66e-94	303.0	COG1352@1|root,COG2201@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HWYQ@117743|Flavobacteriia	976|Bacteroidetes	T	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
k59_676872_1	1172190.M947_10170	8.28e-75	247.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1464895_1	1565129.JSFF01000001_gene1075	1.43e-103	313.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,2Q8HR@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM Na H antiporter NhaC	Z012_10550	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_449460_1	1123514.KB905899_gene756	5.89e-44	153.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yedI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k59_449460_2	317025.Tcr_1071	6.19e-42	140.0	2CBEP@1|root,32RT7@2|Bacteria,1MZXD@1224|Proteobacteria,1SCAX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1010015_1	203119.Cthe_2728	7.24e-08	51.6	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_1010015_2	326298.Suden_0357	4.19e-150	441.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_561064_1	543913.D521_1044	2.24e-91	281.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,1KQFB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_616818_1	1380600.AUYN01000001_gene2257	2.84e-148	430.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1HY11@117743|Flavobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
k59_616818_2	1380600.AUYN01000001_gene2258	5.94e-52	168.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1I3XP@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_1229552_1	411154.GFO_3199	1.36e-180	511.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_1069353_1	393305.YE3348	2.33e-05	49.3	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,41EAH@629|Yersinia	1236|Gammaproteobacteria	NU	General secretion pathway protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_1069353_2	1123514.KB905899_gene431	1.21e-35	132.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,4607Z@72273|Thiotrichales	72273|Thiotrichales	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_1693275_1	1121875.KB907548_gene1625	2.51e-111	335.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k59_224447_1	1172190.M947_08185	4.02e-47	152.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,42VAB@68525|delta/epsilon subdivisions,2YPTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
k59_1195226_1	1380600.AUYN01000012_gene2963	4.44e-309	863.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k59_408062_1	504487.JCM19302_902	1.94e-139	429.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NEWJ@976|Bacteroidetes,1HZA6@117743|Flavobacteriia	976|Bacteroidetes	MU	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14
k59_465004_1	504487.JCM19302_2666	4.54e-81	248.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1HY55@117743|Flavobacteriia	976|Bacteroidetes	G	sugar kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_465004_2	1286632.P278_26670	6.76e-17	79.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_12124_1	326297.Sama_0698	6.68e-86	267.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,1S37I@1236|Gammaproteobacteria,2Q9FY@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
k59_577699_1	572480.Arnit_2639	1.33e-116	350.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2YMJ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_1707416_1	929558.SMGD1_2597	7.9e-74	233.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YMD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_1312564_1	269799.Gmet_3452	3.02e-16	82.4	COG1075@1|root,COG1075@2|Bacteria,1QXAM@1224|Proteobacteria	1224|Proteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
k59_859595_1	948565.AFFP02000011_gene1876	3.86e-51	173.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1Y7YV@135625|Pasteurellales	135625|Pasteurellales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_859595_2	382245.ASA_4229	1.23e-14	72.4	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1Y3ZB@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_295145_1	1380600.AUYN01000007_gene3125	1.93e-136	404.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1029492_1	1172190.M947_02915	3.82e-07	50.4	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k59_1029492_3	563040.Saut_1639	6.19e-12	65.5	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1764141_1	983544.Lacal_0671	6.21e-104	322.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_239175_1	317025.Tcr_1488	1.73e-90	277.0	COG0524@1|root,COG2146@1|root,COG0524@2|Bacteria,COG2146@2|Bacteria,1MWX4@1224|Proteobacteria,1RQW6@1236|Gammaproteobacteria,460KJ@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
k59_350919_1	746697.Aeqsu_0638	3.61e-50	171.0	COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1HY7J@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_350919_2	655815.ZPR_1922	1.39e-30	108.0	2E4IE@1|root,32ZDH@2|Bacteria,4NUR6@976|Bacteroidetes,1I59Y@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
k59_634347_1	1380600.AUYN01000009_gene1292	3.69e-66	209.0	COG1834@1|root,COG1834@2|Bacteria,4NEUJ@976|Bacteroidetes,1HWNG@117743|Flavobacteriia	976|Bacteroidetes	E	Cytochrome C biogenesis protein CcmF	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k59_634347_2	1250006.JHZZ01000001_gene186	1.13e-198	558.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia,3VW0U@52959|Polaribacter	976|Bacteroidetes	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_746708_1	317025.Tcr_1583	8.1e-129	377.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,4609F@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_520774_1	1123518.ARWI01000001_gene448	1.97e-59	190.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,46080@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_520774_2	1123518.ARWI01000001_gene449	1.28e-108	323.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,45ZTV@72273|Thiotrichales	72273|Thiotrichales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_125334_2	1123517.JOMR01000001_gene687	2.05e-11	70.5	COG0457@1|root,COG0457@2|Bacteria,1R9GZ@1224|Proteobacteria,1RZID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,DUF560,TPR_19
k59_1424488_1	655815.ZPR_3223	1.86e-50	166.0	COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,1HYY1@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_1141673_1	1380600.AUYN01000010_gene885	0.0	1169.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1141673_2	1122225.AULQ01000006_gene965	2.33e-203	585.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_1029531_1	697282.Mettu_3159	7.98e-24	101.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XE5X@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_971259_1	563040.Saut_0322	3.75e-34	129.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1651053_1	1137281.D778_02205	1.54e-32	123.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
k59_1651053_2	1392490.JHZX01000001_gene1983	1.5e-128	369.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1HYC6@117743|Flavobacteriia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_1651053_3	1380600.AUYN01000009_gene1019	5.81e-165	490.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
k59_69584_2	203122.Sde_3025	4.66e-08	53.9	COG2207@1|root,COG2207@2|Bacteria,1N8IV@1224|Proteobacteria,1RNPB@1236|Gammaproteobacteria,465F1@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_577801_1	1380600.AUYN01000006_gene363	9.43e-115	339.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,1HXP5@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_295203_1	90814.KL370891_gene1827	3.46e-229	638.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,1RRBV@1236|Gammaproteobacteria,4613Q@72273|Thiotrichales	72273|Thiotrichales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
k59_1424518_1	1172190.M947_08220	3.59e-253	712.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2YNTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_746749_1	323850.Shew_1290	5.42e-43	149.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,2QAME@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037	GcpE
k59_746749_2	1565129.JSFF01000005_gene2306	1.15e-33	125.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,2Q900@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4115)	rodZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k59_1312656_1	1123518.ARWI01000001_gene1861	5.92e-77	241.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,461NY@72273|Thiotrichales	72273|Thiotrichales	U	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
k59_1312656_2	1123518.ARWI01000001_gene1860	3.31e-197	550.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,45ZZM@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k59_1312656_3	745310.G432_06330	1.17e-23	108.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K0BV@204457|Sphingomonadales	204457|Sphingomonadales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,Protoglobin
k59_12213_1	1392498.JQLH01000001_gene2006	7.61e-47	161.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1HXMQ@117743|Flavobacteriia,2PFZY@252356|Maribacter	976|Bacteroidetes	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_12213_2	1317122.ATO12_00185	1.22e-41	146.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,1I2S6@117743|Flavobacteriia,2YIWB@290174|Aquimarina	976|Bacteroidetes	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_12213_3	860228.Ccan_17390	7.8e-249	706.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1HXW2@117743|Flavobacteriia,1ER1Y@1016|Capnocytophaga	976|Bacteroidetes	E	Peptidase, S9A B C family, catalytic domain protein	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_1481441_1	1249975.JQLP01000008_gene380	5.97e-11	62.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia,2P5D6@244698|Gillisia	976|Bacteroidetes	HP	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_1481441_2	1249975.JQLP01000008_gene379	1.17e-94	276.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia,2P6MF@244698|Gillisia	976|Bacteroidetes	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_1481441_3	1249975.JQLP01000008_gene378	7.86e-26	102.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia,2P68D@244698|Gillisia	976|Bacteroidetes	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
k59_408203_1	1033732.CAHI01000030_gene897	1.07e-70	244.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,22UE5@171550|Rikenellaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1594955_1	1380600.AUYN01000001_gene2496	6.84e-169	476.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1HWJN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
k59_1594955_2	1178825.ALIH01000002_gene1052	4.45e-234	651.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1594955_3	1380600.AUYN01000001_gene2498	3.13e-66	202.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1I2X0@117743|Flavobacteriia	976|Bacteroidetes	S	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
k59_1594955_4	504487.JCM19302_194	1.4e-53	177.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_1481451_1	317025.Tcr_2011	8.63e-119	348.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales	72273|Thiotrichales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_182797_1	1121931.AUHG01000015_gene1165	6.95e-91	267.0	COG0454@1|root,COG0456@2|Bacteria,4NQ3C@976|Bacteroidetes,1I3J5@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_182797_2	411154.GFO_0418	9.34e-55	175.0	COG0740@1|root,COG0740@2|Bacteria,4NF77@976|Bacteroidetes,1HXAR@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_1481459_1	1168067.JAGP01000001_gene1677	8.61e-70	218.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1481459_2	1168067.JAGP01000001_gene1676	1.56e-65	207.0	COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,1RY6Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates	amiF	GO:0003674,GO:0003824,GO:0004040,GO:0016787,GO:0016810,GO:0016811	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1537195_1	1121918.ARWE01000001_gene2746	6.28e-107	319.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,43SCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_634432_1	1121931.AUHG01000010_gene767	4.29e-28	107.0	2E5JY@1|root,330B6@2|Bacteria,4NV2G@976|Bacteroidetes,1I56S@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
k59_634432_2	411154.GFO_0111	6.54e-84	257.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
k59_408224_1	1123228.AUIH01000005_gene696	1.66e-114	341.0	COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria,1XHMD@135619|Oceanospirillales	135619|Oceanospirillales	C	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1312668_1	700598.Niako_1861	1.92e-229	646.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,4NGAS@976|Bacteroidetes,1IUW2@117747|Sphingobacteriia	976|Bacteroidetes	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,TPR_8
k59_1312668_2	1122176.KB903545_gene847	3.45e-105	311.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,1IX1N@117747|Sphingobacteriia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1312668_3	1122605.KB893649_gene3757	2.43e-76	243.0	28HI5@1|root,2Z7TP@2|Bacteria,4NET5@976|Bacteroidetes,1IQED@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
k59_1312668_4	1122605.KB893649_gene3757	3.77e-89	276.0	28HI5@1|root,2Z7TP@2|Bacteria,4NET5@976|Bacteroidetes,1IQED@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
k59_1312668_5	1250232.JQNJ01000001_gene815	1.51e-27	102.0	COG5562@1|root,COG5562@2|Bacteria,4NR3A@976|Bacteroidetes,1I3BI@117743|Flavobacteriia	976|Bacteroidetes	S	Phage envelope protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
k59_1029582_1	504487.JCM19302_3875	7.21e-159	451.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
k59_1764258_1	1123517.JOMR01000001_gene1961	2.91e-31	120.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,45ZZX@72273|Thiotrichales	72273|Thiotrichales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF229,HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
k59_1764258_2	90814.KL370891_gene122	7.34e-46	165.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,4604X@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_859732_1	1168067.JAGP01000001_gene1789	6.18e-149	425.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,460K1@72273|Thiotrichales	72273|Thiotrichales	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k59_859732_2	747.DR93_365	4.03e-36	129.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1Y7TF@135625|Pasteurellales	135625|Pasteurellales	J	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_295270_1	572480.Arnit_0472	1.66e-58	189.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2YMDU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k59_295270_2	572480.Arnit_0471	3.03e-70	216.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2YNZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_634458_1	1408473.JHXO01000013_gene608	6.26e-98	316.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_12262_1	504487.JCM19302_2232	7.14e-34	132.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_12262_2	1178825.ALIH01000003_gene2206	2.63e-77	239.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Asp2
k59_634465_1	411154.GFO_1064	5.68e-121	356.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
k59_746819_1	335543.Sfum_3516	1.13e-77	248.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MQTV@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_1255014_1	563040.Saut_0921	2.65e-151	438.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2YMF3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_465205_1	745718.JADT01000004_gene1246	6.12e-87	269.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1HWT2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
k59_465205_2	1197477.IA57_01640	2.88e-20	81.6	COG1983@1|root,COG1983@2|Bacteria,4NSQE@976|Bacteroidetes,1I55A@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_746828_1	1123518.ARWI01000001_gene1401	1.36e-50	178.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,460CJ@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_2,VWA_2
k59_746828_2	90814.KL370892_gene2288	1.69e-113	335.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,4604T@72273|Thiotrichales	72273|Thiotrichales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
k59_634500_1	1380600.AUYN01000009_gene1158	5.45e-91	275.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1HY61@117743|Flavobacteriia	976|Bacteroidetes	E	Acetylornithine deacetylase	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_1031221_3	643867.Ftrac_1319	2.23e-192	541.0	COG1680@1|root,COG1680@2|Bacteria,4PI6S@976|Bacteroidetes,47TUN@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_1031221_4	1121104.AQXH01000001_gene1539	1.1e-48	157.0	COG3860@1|root,COG3860@2|Bacteria,4NX7R@976|Bacteroidetes	976|Bacteroidetes	S	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1031221_5	1443665.JACA01000014_gene4526	6.88e-129	374.0	COG4403@1|root,COG4403@2|Bacteria	2|Bacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
k59_1031221_6	1317122.ATO12_02225	7.75e-46	152.0	2ACN7@1|root,3128Q@2|Bacteria,4PH4J@976|Bacteroidetes,1IND6@117743|Flavobacteriia,2YJT1@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1086672_1	1187848.AJYQ01000156_gene3873	4.53e-31	117.0	COG1280@1|root,COG1280@2|Bacteria,1RASZ@1224|Proteobacteria,1S56X@1236|Gammaproteobacteria,1XX3Q@135623|Vibrionales	135623|Vibrionales	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_538324_1	714943.Mucpa_4859	7.65e-85	259.0	COG0596@1|root,COG0596@2|Bacteria,4NZUP@976|Bacteroidetes,1J0KI@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_367991_2	1150621.SMUL_2788	7.18e-115	338.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2YNXM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_1384343_1	865937.Gilli_0373	3.44e-121	356.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia,2P5XC@244698|Gillisia	976|Bacteroidetes	E	COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1330677_1	929558.SMGD1_0357	2.34e-75	248.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2YM8C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_200100_1	1565129.JSFF01000001_gene1153	6.54e-41	147.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1T1RS@1236|Gammaproteobacteria,2QARM@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	sapA	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K19226	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	SBP_bac_5
k59_200100_2	398579.Spea_2670	1.08e-22	97.1	COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria,2QAXU@267890|Shewanellaceae	1236|Gammaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_1441198_1	1123228.AUIH01000024_gene3244	1.68e-28	103.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XM6U@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_1441198_2	1123228.AUIH01000024_gene3243	1.08e-43	143.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XKR2@135619|Oceanospirillales	135619|Oceanospirillales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_877167_1	1121931.AUHG01000012_gene2576	1.43e-151	427.0	28MAJ@1|root,2ZAP7@2|Bacteria,4NJIX@976|Bacteroidetes,1I108@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_594408_1	1406840.Q763_09600	4.46e-43	147.0	COG0358@1|root,COG0358@2|Bacteria,4NH5X@976|Bacteroidetes,1I03T@117743|Flavobacteriia,2NVRI@237|Flavobacterium	976|Bacteroidetes	L	DNA primase	traP	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,zf-CHC2
k59_594408_2	1406840.Q763_09605	1.62e-127	362.0	COG3911@1|root,COG3911@2|Bacteria,4NNT6@976|Bacteroidetes,1IGIG@117743|Flavobacteriia,2NZ43@237|Flavobacterium	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k59_594408_3	1406840.Q763_09610	1.3e-58	182.0	2E69Y@1|root,330XV@2|Bacteria,4NWWP@976|Bacteroidetes,1IBSD@117743|Flavobacteriia,2NX7Q@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_594408_4	1406840.Q763_09615	1.96e-43	141.0	2DGGG@1|root,2ZVWD@2|Bacteria,4P761@976|Bacteroidetes,1IB8Z@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_594408_5	1406840.Q763_09620	2.72e-226	629.0	COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,1I02W@117743|Flavobacteriia,2NT2S@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	yjiR	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_482625_1	1273125.Rrhod_1180	1.63e-18	86.3	COG1028@1|root,COG1028@2|Bacteria,2GVVR@201174|Actinobacteria,4FVF8@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_482625_2	143224.JQMD01000002_gene1615	5.63e-221	618.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_1553982_1	1191523.MROS_0879	5.92e-06	55.5	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	pemA	GO:0005575,GO:0005576	3.1.1.11	ko:K01051,ko:K10297	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko04121	-	-	-	Beta_helix,Pectinesterase,Pkinase
k59_538386_1	926551.KB900708_gene1158	2.91e-61	201.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1HY28@117743|Flavobacteriia,1ERIX@1016|Capnocytophaga	976|Bacteroidetes	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_312729_1	709032.Sulku_2393	1.66e-91	273.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2YMNS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	-	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_312729_2	350688.Clos_1108	1.6e-09	66.6	COG0535@1|root,COG0535@2|Bacteria,1V0CR@1239|Firmicutes,24BIB@186801|Clostridia,36G4D@31979|Clostridiaceae	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_1553988_1	563040.Saut_1114	2.92e-70	220.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2YMR0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_1553988_2	563040.Saut_1115	3.54e-80	250.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2YTA6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1553989_1	305700.B447_06792	1.65e-91	281.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,2KXVI@206389|Rhodocyclales	206389|Rhodocyclales	U	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2,DUF3382
k59_368060_1	323850.Shew_0544	1.71e-104	314.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,2Q8VZ@267890|Shewanellaceae	1236|Gammaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	tolC	GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	iAPECO1_1312.APECO1_3378,iEC042_1314.EC042_3326,iECOK1_1307.ECOK1_3463	OEP
k59_651785_2	504487.JCM19302_3174	1.4e-192	537.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1046579_1	1565129.JSFF01000025_gene1328	7.49e-87	259.0	COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,1S4F0@1236|Gammaproteobacteria,2Q9KY@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
k59_87069_1	929558.SMGD1_1005	6.11e-58	185.0	COG2731@1|root,COG2731@2|Bacteria,1N8IZ@1224|Proteobacteria,42W19@68525|delta/epsilon subdivisions,2YSZX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
k59_1272356_1	472175.EL18_01955	8.65e-15	80.5	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U0ME@28211|Alphaproteobacteria,43QDB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	N	Integrin alpha (beta-propellor repeats).	exsH	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Glyco_hydro_16,HemolysinCabind,W_rich_C
k59_1668451_1	929558.SMGD1_2763	1.82e-117	355.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YNJ4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_142321_1	572480.Arnit_3029	7.05e-99	301.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1499401_1	563040.Saut_0660	3.12e-28	112.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2YN4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
k59_1499401_2	436308.Nmar_1006	7.32e-74	245.0	COG0598@1|root,arCOG02265@2157|Archaea	2157|Archaea	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_1499401_3	929558.SMGD1_1030	1.67e-13	68.9	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,42SFK@68525|delta/epsilon subdivisions,2YPP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k59_312740_1	1380384.JADN01000007_gene1487	5.68e-229	647.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1HXUQ@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_312740_2	555079.Toce_1878	1.6e-44	163.0	COG1609@1|root,COG1609@2|Bacteria,1TRZW@1239|Firmicutes,24I0I@186801|Clostridia,42I2Z@68295|Thermoanaerobacterales	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k59_312740_3	504472.Slin_1274	2.18e-130	413.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47NVQ@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_538416_1	261292.Nit79A3_1825	3.89e-28	116.0	2DFT6@1|root,2ZT1X@2|Bacteria,1PAHV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1724933_1	1380600.AUYN01000009_gene1593	0.0	902.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_1668463_2	1380600.AUYN01000003_gene142	1.2e-55	175.0	COG2198@1|root,COG2198@2|Bacteria,4NVS6@976|Bacteroidetes,1I5MU@117743|Flavobacteriia	976|Bacteroidetes	T	(Hpt) domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k59_932824_1	176299.Atu3094	9.57e-18	84.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,4B98A@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_3,PAS_4
k59_28698_1	1121931.AUHG01000018_gene1375	1.62e-159	462.0	COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,1HWTJ@117743|Flavobacteriia	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_28698_2	1121931.AUHG01000018_gene1376	4.58e-05	43.9	COG2149@1|root,COG2149@2|Bacteria,4NWFQ@976|Bacteroidetes,1I2WP@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
k59_87092_1	929558.SMGD1_0141	3.79e-36	135.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2YNEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Membrane-bound lytic murein transglycosylase C	mltC	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k59_87092_2	1172190.M947_09290	1.11e-17	76.3	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2YPE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	Hit family	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_985227_1	1121875.KB907547_gene3444	1.14e-91	289.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_763659_1	1537915.JU57_01760	5.77e-33	123.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,42VZ2@68525|delta/epsilon subdivisions,2YQGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM Ferric reductase domain protein transmembrane component domain	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_763659_2	1249480.B649_01355	3.84e-16	76.3	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,42P5V@68525|delta/epsilon subdivisions,2YNBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_877265_1	411154.GFO_2326	7.85e-56	187.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1HY1T@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_877265_2	411154.GFO_2325	1.82e-38	138.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1HX2N@117743|Flavobacteriia	976|Bacteroidetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1554039_2	1286631.X805_40670	5.53e-19	85.5	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1102246_1	1137281.D778_01925	3.53e-96	302.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k59_142355_1	1250005.PHEL85_0790	7.61e-90	269.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,1HXDB@117743|Flavobacteriia,3VVB6@52959|Polaribacter	976|Bacteroidetes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_142355_2	1123234.AUKI01000021_gene941	1.6e-57	189.0	COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,1HX2Y@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1499446_1	90813.JQMT01000001_gene1855	2.64e-50	175.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,4609S@72273|Thiotrichales	72273|Thiotrichales	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_877282_1	313603.FB2170_10334	2.34e-101	307.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	yqkD	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_877282_2	269798.CHU_2400	6.01e-32	116.0	COG3832@1|root,COG3832@2|Bacteria,4NRH6@976|Bacteroidetes,47V72@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_822175_1	90814.KL370891_gene83	2.99e-49	159.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,460XU@72273|Thiotrichales	72273|Thiotrichales	E	PFAM phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k59_822175_2	317025.Tcr_1971	1.03e-64	197.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales	72273|Thiotrichales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
k59_822175_3	1123514.KB905899_gene1969	1.91e-31	112.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,461D2@72273|Thiotrichales	72273|Thiotrichales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_87130_1	317025.Tcr_2139	2.69e-113	335.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,462Q0@72273|Thiotrichales	72273|Thiotrichales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k59_87130_2	317025.Tcr_2140	6.64e-45	155.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S2WF@1236|Gammaproteobacteria,46277@72273|Thiotrichales	72273|Thiotrichales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k59_87133_1	1565129.JSFF01000001_gene815	7.51e-92	278.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,2QAP6@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_1330826_1	270374.MELB17_08396	2.74e-55	176.0	COG2148@1|root,COG2148@2|Bacteria,1R4J5@1224|Proteobacteria,1RP9R@1236|Gammaproteobacteria,466P1@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Bacterial sugar transferase	wbfU	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k59_1330826_2	90814.KL370891_gene417	1.01e-49	167.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,45ZWC@72273|Thiotrichales	72273|Thiotrichales	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_1615222_1	411154.GFO_2712	3.21e-147	421.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1HYAD@117743|Flavobacteriia	976|Bacteroidetes	C	NADH flavin oxidoreductase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
k59_653722_1	1121935.AQXX01000078_gene1559	2.27e-38	137.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1XIXQ@135619|Oceanospirillales	135619|Oceanospirillales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_1726777_1	1121931.AUHG01000011_gene1815	3.33e-113	334.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_1726777_2	411154.GFO_2700	3.56e-41	135.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,1I51R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1726777_3	411154.GFO_2699	1.3e-27	106.0	COG2335@1|root,COG2335@2|Bacteria,4NP03@976|Bacteroidetes,1I2I1@117743|Flavobacteriia	976|Bacteroidetes	M	COGs COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_712487_1	572480.Arnit_0834	3.03e-97	292.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42M7C@68525|delta/epsilon subdivisions,2YTS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_712487_2	929558.SMGD1_1459	1.11e-11	63.9	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2YR33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_484523_1	953739.SVEN_6401	1.84e-20	97.8	COG0488@1|root,COG0488@2|Bacteria,2GJHN@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_484523_2	1172190.M947_05515	3.71e-31	110.0	COG4895@1|root,COG4895@2|Bacteria,1N7TD@1224|Proteobacteria,42V1D@68525|delta/epsilon subdivisions,2YQJ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
k59_1555848_1	411154.GFO_0625	5.39e-41	138.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,1I27H@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
k59_1555848_2	1121931.AUHG01000016_gene945	2.28e-112	328.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_1443120_1	90814.KL370891_gene1387	7.74e-109	321.0	COG0697@1|root,COG0697@2|Bacteria,1RM06@1224|Proteobacteria,1SQ65@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_540243_1	1121937.AUHJ01000012_gene2805	1.62e-58	186.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,466ZT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
k59_144287_1	90814.KL370891_gene1715	2.38e-77	245.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K07717,ko:K15011	ko02020,map02020	M00518,M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_5,HisKA
k59_144287_2	90814.KL370891_gene1713	1.09e-27	105.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_427544_1	411154.GFO_0506	9.28e-184	514.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1HXY0@117743|Flavobacteriia	976|Bacteroidetes	S	abc transporter (atp-binding protein)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_427544_2	411154.GFO_0507	9.89e-14	70.1	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1HXQA@117743|Flavobacteriia	976|Bacteroidetes	CP	ABC transporter (Permease)	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_1274249_1	1506583.JQJY01000002_gene1721	1.14e-49	166.0	COG1520@1|root,COG1520@2|Bacteria,4PMB8@976|Bacteroidetes,1IJQD@117743|Flavobacteriia,2P0T5@237|Flavobacterium	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusE
k59_1784188_1	1172190.M947_08660	2.52e-65	219.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_712516_1	1565129.JSFF01000001_gene1067	8.63e-93	275.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,2Q9U0@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0066	yaeB	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_824247_1	865937.Gilli_0494	1.11e-51	182.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia,2P6HC@244698|Gillisia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
k59_88935_1	1121481.AUAS01000006_gene877	8.78e-27	114.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
k59_427560_1	1123518.ARWI01000001_gene29	6.51e-107	312.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,460EJ@72273|Thiotrichales	72273|Thiotrichales	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_1443174_1	504487.JCM19302_2502	7.4e-90	271.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1443174_2	1380600.AUYN01000001_gene2271	1.24e-42	154.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_555441_2	1168067.JAGP01000001_gene1638	1.82e-100	299.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,460TR@72273|Thiotrichales	72273|Thiotrichales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_219095_1	1168067.JAGP01000001_gene603	1.05e-50	172.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,45ZRY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_219095_2	1123518.ARWI01000001_gene776	8.13e-258	736.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,45ZPD@72273|Thiotrichales	72273|Thiotrichales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_1291266_1	1392489.JPOL01000002_gene1276	1.63e-49	166.0	COG0657@1|root,COG0657@2|Bacteria,4PKDQ@976|Bacteroidetes,1HXR3@117743|Flavobacteriia,2XJTJ@283735|Leeuwenhoekiella	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_1291266_2	1124780.ANNU01000032_gene1227	2.21e-67	233.0	COG3540@1|root,COG4677@1|root,COG3540@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	pel	-	3.1.1.11,3.1.4.3,3.2.1.82	ko:K01051,ko:K01114,ko:K10297,ko:K18650	ko00040,ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00040,map00562,map00564,map00565,map01100,map01110,map02024,map04919	M00081	R01312,R02027,R02052,R02362,R03332,R07381	RC00017,RC00425,RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko02042,ko04121	-	GH28	-	Beta_helix,Big_3,Pectinesterase,Pkinase
k59_160439_1	1223410.KN050846_gene1405	1.06e-65	199.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes,1I2UD@117743|Flavobacteriia	976|Bacteroidetes	Q	With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
k59_160439_2	1197477.IA57_02145	3.45e-87	261.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia	976|Bacteroidetes	S	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_783090_1	929558.SMGD1_2310	1.2e-75	239.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2YMUP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	na -driven multidrug efflux	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_783090_2	326298.Suden_1360	1.95e-34	120.0	2BJZK@1|root,32ECD@2|Bacteria,1QDIV@1224|Proteobacteria,433KD@68525|delta/epsilon subdivisions,2YSRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160445_1	1121931.AUHG01000010_gene293	1.49e-81	261.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_501229_1	1172190.M947_11650	1.43e-96	310.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1063887_1	563040.Saut_1354	5.18e-120	348.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2YNUX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_838386_1	1121912.AUHD01000006_gene1427	6.32e-115	342.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_1178105_1	563040.Saut_1473	3.49e-101	302.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2YN69@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_555496_1	1046627.BZARG_66	1.45e-79	247.0	COG0247@1|root,COG0247@2|Bacteria,4PM9R@976|Bacteroidetes,1IJNY@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
k59_555496_2	1392490.JHZX01000001_gene3145	1.84e-33	121.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k59_501241_1	1550091.JROE01000004_gene1883	1.52e-29	114.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_501241_2	1120948.KB903243_gene2566	1.49e-10	64.3	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EAYA@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
k59_1801297_1	1565129.JSFF01000011_gene1982	9.2e-123	372.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,2Q97E@267890|Shewanellaceae	1236|Gammaproteobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_2160,iPC815.YPO2428	B3_4,B5,FDX-ACB,tRNA_bind
k59_948595_1	411154.GFO_2933	8.85e-125	379.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1063925_1	1123487.KB892836_gene3191	3.15e-103	308.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,2KUKP@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_783147_1	983544.Lacal_0361	3.08e-144	424.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_387012_1	1232410.KI421418_gene2280	7.42e-104	310.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,43S8Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aconitase family (aconitate hydratase)	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_387012_2	1232410.KI421418_gene2279	2e-05	45.8	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,43S1Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	LeuA allosteric (dimerisation) domain	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_1121614_1	1123228.AUIH01000039_gene2900	6.1e-64	219.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1291336_1	1172190.M947_09110	8.22e-76	230.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2YNC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel family	tolQ	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_1291336_2	929558.SMGD1_2273	8.2e-45	148.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2YPWF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k59_611177_1	631362.Thi970DRAFT_04272	2.49e-25	96.7	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1WYUC@135613|Chromatiales	135613|Chromatiales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
k59_611177_2	1122207.MUS1_03305	1.68e-34	129.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XIJ5@135619|Oceanospirillales	135619|Oceanospirillales	O	ATPase with chaperone activity	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1291358_1	572480.Arnit_0410	2.79e-22	95.5	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_1291358_2	572480.Arnit_0411	2.82e-128	371.0	COG0152@1|root,COG0152@2|Bacteria	2|Bacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SAICAR_synt
k59_1744531_1	85643.Tmz1t_3916	5.24e-21	87.4	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,2KW7R@206389|Rhodocyclales	206389|Rhodocyclales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1744531_2	497321.C664_19116	1.25e-54	186.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KV4F@206389|Rhodocyclales	206389|Rhodocyclales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_948654_1	1137281.D778_00181	0.0	1015.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_160545_1	517418.Ctha_1124	9.9e-41	142.0	2DBIE@1|root,32TXH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1572430_1	1123037.AUDE01000001_gene1707	2.46e-35	129.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1HXN8@117743|Flavobacteriia	976|Bacteroidetes	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
k59_1572430_2	1197477.IA57_05475	7.55e-84	251.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k59_46401_1	85643.Tmz1t_1261	1.79e-57	189.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,2KUTI@206389|Rhodocyclales	206389|Rhodocyclales	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_1402602_2	487796.Flav2ADRAFT_1675	4.41e-09	56.2	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,1HXXT@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_1459358_1	983545.Glaag_2308	3.39e-30	110.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,1SB3Z@1236|Gammaproteobacteria,468JQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_1459358_2	686340.Metal_2739	4.71e-17	77.0	COG4978@1|root,COG4978@2|Bacteria,1N06E@1224|Proteobacteria,1SFTG@1236|Gammaproteobacteria,1XGBH@135618|Methylococcales	135618|Methylococcales	KT	PFAM Bacterial transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
k59_838475_1	1172190.M947_07980	1.43e-62	201.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2YNF1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_1223885_1	313603.FB2170_04245	1.45e-43	147.0	COG2314@1|root,COG2314@2|Bacteria,4NSVZ@976|Bacteroidetes,1I3HF@117743|Flavobacteriia,2PHN1@252356|Maribacter	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
k59_1223885_2	1380600.AUYN01000006_gene715	3.05e-152	443.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_783252_1	411154.GFO_0426	2.1e-172	495.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_783252_2	411154.GFO_0425	3.33e-150	427.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_783252_3	1121931.AUHG01000015_gene1168	9.17e-42	140.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_1404121_1	425104.Ssed_3153	5e-149	442.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,2Q8GK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1006162_1	318167.Sfri_1126	4.92e-106	319.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,2Q98B@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_334007_1	443152.MDG893_20549	1.59e-23	104.0	COG4733@1|root,COG4733@2|Bacteria,1R77Q@1224|Proteobacteria,1S1WT@1236|Gammaproteobacteria,469QU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1803202_1	317025.Tcr_0607	3.1e-62	198.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,460CM@72273|Thiotrichales	72273|Thiotrichales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1803202_2	1123514.KB905899_gene558	3.72e-87	260.0	COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,1S4I3@1236|Gammaproteobacteria,462TD@72273|Thiotrichales	72273|Thiotrichales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_1803202_3	1168067.JAGP01000001_gene673	9.18e-15	70.5	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k59_1803202_4	317025.Tcr_0605	4.87e-31	122.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,460B5@72273|Thiotrichales	72273|Thiotrichales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_1803202_5	717772.THIAE_01285	4.42e-05	45.8	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,460B5@72273|Thiotrichales	72273|Thiotrichales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_1352200_1	1239962.C943_01650	1.19e-100	323.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_220947_1	1236541.BALL01000010_gene1658	4.03e-46	167.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,2Q8IT@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iECIAI1_1343.ECIAI1_0973,iECO103_1326.ECO103_0977,iECP_1309.ECP_0944,iECSE_1348.ECSE_0993,iECW_1372.ECW_m1042,iEKO11_1354.EKO11_2898,iWFL_1372.ECW_m1042	DUF3458,DUF3458_C,Peptidase_M1
k59_220947_2	323850.Shew_1802	2.42e-09	57.4	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,2Q96B@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k59_1006197_1	1101191.KI912577_gene490	2.33e-06	57.0	COG0438@1|root,COG0438@2|Bacteria,1PEW5@1224|Proteobacteria,2U8TS@28211|Alphaproteobacteria,1JR2X@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_1006198_1	1208321.D104_12410	5.96e-15	74.7	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,1XJZX@135619|Oceanospirillales	135619|Oceanospirillales	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
k59_1006198_2	1042375.AFPL01000010_gene446	2.2e-54	175.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,465V8@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
k59_613128_1	572480.Arnit_1480	2.61e-112	325.0	COG0476@1|root,COG0476@2|Bacteria,1P1FY@1224|Proteobacteria,42PK6@68525|delta/epsilon subdivisions,2YNCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_613128_2	484022.Fphi_1826	2.8e-110	325.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,1RPNB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3943 Virulence protein	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
k59_162483_1	411154.GFO_3507	2.04e-98	303.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
k59_1352242_1	1121859.KB890754_gene894	6.81e-10	65.9	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_1521032_1	572480.Arnit_1927	1.94e-106	317.0	COG0665@1|root,COG0665@2|Bacteria,1Q0BQ@1224|Proteobacteria,42RXA@68525|delta/epsilon subdivisions,2YP66@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0665 Glycine D-amino acid oxidase (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1746518_1	1121011.AUCB01000008_gene1240	7.41e-80	265.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HZ82@117743|Flavobacteriia	976|Bacteroidetes	G	Kelch	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_3,Kelch_4,Kelch_6,Malectin,PKD
k59_48182_2	572480.Arnit_0192	1.51e-13	69.7	COG4974@1|root,COG4974@2|Bacteria,1QUFQ@1224|Proteobacteria,43CG3@68525|delta/epsilon subdivisions,2YTMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_1689637_1	411154.GFO_0179	9.59e-109	335.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1HXS7@117743|Flavobacteriia	976|Bacteroidetes	C	Malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_785236_1	1303518.CCALI_01464	3.87e-10	62.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1461230_1	1137281.D778_00737	1.03e-117	377.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2
k59_334122_1	1415778.JQMM01000001_gene274	3.18e-84	257.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1J4D2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Pribosyl_synth,Pribosyltran_N
k59_1225901_1	497321.C664_06978	8.57e-43	150.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,2KUW2@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1225901_2	863365.XHC_1117	1.09e-24	95.1	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1X7EF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_1689653_1	1123037.AUDE01000011_gene969	7.72e-58	183.0	COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,1I2V7@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1689653_2	504487.JCM19302_3478	3.4e-69	218.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,1HXPJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
k59_275560_1	1322246.BN4_11820	4.49e-13	73.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M7RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k59_731983_1	556269.ACDQ01000006_gene1526	6.52e-69	222.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,2VJ9B@28216|Betaproteobacteria,4772D@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Virulence protein RhuM family	rhuM	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
k59_785253_1	497321.C664_03000	3.39e-108	321.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,2KUCX@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_48219_1	563040.Saut_1622	3.94e-148	447.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_108411_1	382464.ABSI01000002_gene4385	7.11e-29	114.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,2IVG0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamine synthetase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Gln-synt_C
k59_108411_2	1123514.KB905899_gene1360	2.74e-96	286.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,1RR9A@1236|Gammaproteobacteria,46233@72273|Thiotrichales	72273|Thiotrichales	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_950321_1	1123518.ARWI01000001_gene2471	4.8e-155	436.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales	72273|Thiotrichales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_950321_2	1122134.KB893650_gene1115	7.56e-28	107.0	COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,1RRAF@1236|Gammaproteobacteria,1XJEV@135619|Oceanospirillales	135619|Oceanospirillales	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
k59_613246_1	983544.Lacal_1223	6.76e-55	174.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I27K@117743|Flavobacteriia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_613246_4	992406.RIA_0183	1.65e-31	114.0	COG1694@1|root,COG1694@2|Bacteria,4NXGF@976|Bacteroidetes,1IB36@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1352347_1	572480.Arnit_2712	1e-200	573.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2YNP4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_950334_1	746697.Aeqsu_1573	6.8e-14	73.2	COG2356@1|root,COG2356@2|Bacteria,4PMQN@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1421599_1	983544.Lacal_0150	2.6e-83	258.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_1082047_1	1042376.AFPK01000031_gene874	3.51e-27	115.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG2202@1|root,COG4372@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4372@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia,4070G@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_9364_1	1121931.AUHG01000010_gene465	6.66e-111	330.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1HY45@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
k59_179598_1	411154.GFO_2068	2.98e-90	285.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_574636_1	1137281.D778_02778	7.9e-115	332.0	COG2824@1|root,COG2824@2|Bacteria,4NEFZ@976|Bacteroidetes,1I01B@117743|Flavobacteriia	976|Bacteroidetes	P	PhnA protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k59_574636_2	1484460.JSWG01000009_gene511	9.44e-67	214.0	28HRC@1|root,2Z7YT@2|Bacteria,4NKDD@976|Bacteroidetes,1HYNI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1648019_1	411154.GFO_2349	8.84e-184	513.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,1HZ2R@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1704315_1	1123518.ARWI01000001_gene1492	8.87e-45	152.0	2EN7Y@1|root,33FVR@2|Bacteria,1NHR8@1224|Proteobacteria,1SH6M@1236|Gammaproteobacteria,46388@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1704315_2	1278307.KB907004_gene161	2.24e-38	149.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QIZI@267894|Psychromonadaceae	1236|Gammaproteobacteria	NT	helical bimodular (HBM) domain	-	-	-	ko:K03406,ko:K10937	ko02020,ko02030,ko05111,map02020,map02030,map05111	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_1138824_1	1200567.JNKD01000005_gene72	3.91e-23	94.4	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1Y4QX@135624|Aeromonadales	135624|Aeromonadales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_1138824_2	518766.Rmar_0907	5.99e-17	74.7	COG1993@1|root,COG1993@2|Bacteria,4NX2K@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
k59_179608_1	411154.GFO_2801	1.84e-114	331.0	COG2095@1|root,COG2095@2|Bacteria,4NIHF@976|Bacteroidetes,1HY3F@117743|Flavobacteriia	976|Bacteroidetes	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_743693_1	203119.Cthe_2474	1.41e-14	83.2	COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,3WH9W@541000|Ruminococcaceae	186801|Clostridia	S	Phage terminase, large subunit, PBSX family	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_2,Terminase_3,Terminase_3C
k59_1138827_1	1121912.AUHD01000002_gene3184	7.8e-74	234.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1I0Q4@117743|Flavobacteriia	976|Bacteroidetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
k59_1138827_2	1121875.KB907546_gene2670	2.39e-130	386.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Porphobil_deam,Shikimate_DH
k59_405290_1	655815.ZPR_2537	3.99e-226	630.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,1HYDJ@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k59_405290_2	1484460.JSWG01000009_gene376	6.96e-57	184.0	COG0664@1|root,COG0664@2|Bacteria,4NKGK@976|Bacteroidetes,1I2MF@117743|Flavobacteriia	976|Bacteroidetes	T	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_1704334_1	929558.SMGD1_0299	1.99e-73	233.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1761068_2	883168.HMPREF9318_00679	6.19e-25	104.0	COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,4HHPV@91061|Bacilli	91061|Bacilli	M	COG0463, glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K12997	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
k59_1026763_1	1121931.AUHG01000012_gene2611	3.88e-94	296.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HY5H@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_800877_1	1565129.JSFF01000014_gene396	1.16e-29	111.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,2Q9DM@267890|Shewanellaceae	1236|Gammaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710	adh_short_C2
k59_1309507_1	391603.FBALC1_14207	4.39e-143	413.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWZU@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the thiolase family	pcaF	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_1309507_2	1111730.ATTM01000003_gene606	1.8e-55	174.0	COG2827@1|root,COG2827@2|Bacteria,4NTI8@976|Bacteroidetes,1I4YS@117743|Flavobacteriia,2NXAC@237|Flavobacterium	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k59_1309507_3	641526.ADIWIN_2317	3.8e-46	164.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia	976|Bacteroidetes	CI	phenylacetic acid degradation protein paaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
k59_9400_1	443152.MDG893_01260	2.02e-05	47.8	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,4662T@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_9400_2	319224.Sputcn32_2541	1.34e-13	72.4	COG3765@1|root,COG3765@2|Bacteria,1MXGW@1224|Proteobacteria,1RPE4@1236|Gammaproteobacteria,2Q9PM@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM lipopolysaccharide biosynthesis	wzz	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_405310_1	323850.Shew_0743	5.6e-43	152.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,2Q97N@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_405310_2	323850.Shew_0744	4.4e-08	52.4	COG3187@1|root,COG3187@2|Bacteria,1N78G@1224|Proteobacteria,1SG3U@1236|Gammaproteobacteria,2QC8W@267890|Shewanellaceae	1236|Gammaproteobacteria	O	META domain	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
k59_1534213_1	317025.Tcr_0204	1.21e-129	384.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,4608N@72273|Thiotrichales	72273|Thiotrichales	MU	TIGRFAM type I secretion outer membrane protein, TolC family	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
k59_1534213_2	90814.KL370891_gene137	4.33e-52	172.0	COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,1SFFJ@1236|Gammaproteobacteria,461EY@72273|Thiotrichales	72273|Thiotrichales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_631209_1	1347342.BN863_4620	8.31e-101	310.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_236227_1	1565129.JSFF01000014_gene386	8.31e-25	108.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,2Q9K1@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	PNPase_C,RNase_E_G,S1
k59_237985_1	929558.SMGD1_0459	5.62e-86	280.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2YMHU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1028463_1	686340.Metal_3173	4.21e-77	261.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_9
k59_1311283_1	1144313.PMI10_03512	1.73e-217	623.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
k59_1311283_2	376686.Fjoh_2039	1.64e-241	689.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
k59_1535906_1	1123518.ARWI01000001_gene1759	5.32e-126	369.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,460S7@72273|Thiotrichales	72273|Thiotrichales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k59_1535906_2	90814.KL370891_gene1878	7.06e-142	406.0	COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,1RMES@1236|Gammaproteobacteria,4626Y@72273|Thiotrichales	72273|Thiotrichales	H	TOBE domain	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
k59_1535906_3	317025.Tcr_1927	5.47e-06	48.5	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,4624T@72273|Thiotrichales	72273|Thiotrichales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_407011_1	398720.MED217_11499	8.32e-26	111.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia,2XISK@283735|Leeuwenhoekiella	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
k59_519542_1	929558.SMGD1_2543	2.26e-145	429.0	COG1315@1|root,COG1315@2|Bacteria,1R5P6@1224|Proteobacteria,42MAS@68525|delta/epsilon subdivisions,2YM7Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Flagellar Assembly Protein A	-	-	-	-	-	-	-	-	-	-	-	-	FapA
k59_802648_1	985255.APHJ01000017_gene2153	1.8e-43	149.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,1IISJ@117743|Flavobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
k59_802648_2	1121931.AUHG01000011_gene2406	4.85e-102	308.0	COG1215@1|root,COG1215@2|Bacteria,4NEG0@976|Bacteroidetes,1HXHU@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Glycos_transf_2
k59_1649757_1	985255.APHJ01000021_gene1335	9.43e-93	296.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2P76V@244698|Gillisia	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
k59_914929_1	929558.SMGD1_2449	1.01e-53	187.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1PGYK@1224|Proteobacteria,42YPW@68525|delta/epsilon subdivisions,2YR2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_802651_2	983544.Lacal_1173	5.07e-66	201.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
k59_802651_3	1380600.AUYN01000006_gene638	1.92e-82	246.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1I1A5@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
k59_633015_1	1121931.AUHG01000020_gene3167	5.97e-178	501.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_970331_2	411154.GFO_2539	2.6e-91	283.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia	976|Bacteroidetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1480074_1	1166948.JPZL01000003_gene780	1.06e-16	77.0	COG3043@1|root,COG3043@2|Bacteria,1RHGD@1224|Proteobacteria,1S84V@1236|Gammaproteobacteria,1XPQE@135619|Oceanospirillales	135619|Oceanospirillales	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
k59_1480074_2	999611.KI421504_gene481	6.6e-58	198.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2805V@191028|Leisingera	28211|Alphaproteobacteria	C	Molydopterin dinucleotide binding domain	napA	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114	-	ko:K00372,ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530,M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_690065_1	572480.Arnit_1398	8.86e-97	301.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1706174_1	1565129.JSFF01000006_gene2550	7.4e-114	338.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,2QA31@267890|Shewanellaceae	1236|Gammaproteobacteria	M	cell wall hydrolase autolysin	amiB	GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	iG2583_1286.G2583_4996	AMIN,Amidase_3,LysM
k59_68230_1	572480.Arnit_0236	1.94e-06	48.5	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2YN1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_68230_2	572480.Arnit_0237	1.07e-87	264.0	COG0124@1|root,COG0124@2|Bacteria,1QUJQ@1224|Proteobacteria,42NX2@68525|delta/epsilon subdivisions,2YN2F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_914946_2	1565129.JSFF01000026_gene1234	6.01e-13	70.9	COG3210@1|root,COG3210@2|Bacteria,1QXF2@1224|Proteobacteria,1T3A4@1236|Gammaproteobacteria,2QETX@267890|Shewanellaceae	1236|Gammaproteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1253675_1	504487.JCM19302_3410	2.58e-28	116.0	COG4886@1|root,COG4886@2|Bacteria,4NI2K@976|Bacteroidetes,1I0CI@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Leucine Rich Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_6,LRR_8
k59_1253675_2	1469557.JSWF01000033_gene1563	8.52e-14	65.5	2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
k59_1253678_1	1178825.ALIH01000007_gene1648	1.62e-26	105.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
k59_1253678_2	886377.Murru_1933	8.79e-42	139.0	COG0296@1|root,COG0296@2|Bacteria,4NSTP@976|Bacteroidetes,1I4C7@117743|Flavobacteriia	976|Bacteroidetes	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
k59_1253678_3	313603.FB2170_17276	8.11e-97	286.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia,2PGWA@252356|Maribacter	976|Bacteroidetes	F	Thymidylate synthase	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_576466_1	411154.GFO_0031	0.0	1120.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k59_349777_1	1353528.DT23_17275	4.34e-128	374.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,2TTA9@28211|Alphaproteobacteria,2XMSP@285107|Thioclava	28211|Alphaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_349777_2	1353528.DT23_17270	7.34e-06	47.0	COG3279@1|root,COG3279@2|Bacteria,1N903@1224|Proteobacteria,2UCXI@28211|Alphaproteobacteria,2XP3U@285107|Thioclava	28211|Alphaproteobacteria	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
k59_1593754_1	1121931.AUHG01000011_gene2323	7.25e-81	249.0	COG1609@1|root,COG1609@2|Bacteria,4NJDR@976|Bacteroidetes,1I07H@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k59_1366226_1	1137281.D778_02536	9.56e-139	405.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_1649817_1	323850.Shew_0628	2.17e-56	197.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,2Q96R@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_970360_1	641112.ACOK01000112_gene2097	2.36e-27	111.0	COG3680@1|root,COG3680@2|Bacteria,1VBR1@1239|Firmicutes,258FX@186801|Clostridia,3WMMI@541000|Ruminococcaceae	186801|Clostridia	O	regulation of methylation-dependent chromatin silencing	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_970360_2	1484460.JSWG01000001_gene2242	4.87e-42	143.0	COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,1I11I@117743|Flavobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
k59_745532_1	264462.Bd2640	1.46e-33	135.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2MSM8@213481|Bdellovibrionales,2WIUS@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1762937_1	1046627.BZARG_444	2.35e-85	274.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_1762941_1	1484460.JSWG01000009_gene514	9.6e-28	104.0	COG1366@1|root,COG1366@2|Bacteria,4NVTC@976|Bacteroidetes,1I55J@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
k59_1762941_2	1380600.AUYN01000006_gene457	4.35e-130	379.0	COG4192@1|root,COG4192@2|Bacteria,4NFY7@976|Bacteroidetes,1HX1N@117743|Flavobacteriia	976|Bacteroidetes	T	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
k59_1311368_1	319224.Sputcn32_0639	2.24e-17	80.9	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,2Q9IT@267890|Shewanellaceae	1236|Gammaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	yajR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1311368_2	1336233.JAEH01000031_gene225	5.25e-76	233.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,2Q8X8@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_690118_1	1121912.AUHD01000017_gene3521	1.79e-80	255.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_690118_2	1484460.JSWG01000008_gene2042	2.29e-149	423.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_690118_3	1380600.AUYN01000009_gene1300	5.48e-162	456.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1HXNN@117743|Flavobacteriia	976|Bacteroidetes	Q	abc transporter (atp-binding protein)	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_690118_5	1178825.ALIH01000020_gene2706	1.12e-48	160.0	COG4083@1|root,COG4083@2|Bacteria	2|Bacteria	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
k59_1083865_1	1122225.AULQ01000016_gene1948	6.97e-59	207.0	COG1345@1|root,COG3227@1|root,COG3897@1|root,COG1345@2|Bacteria,COG3227@2|Bacteria,COG3897@2|Bacteria,4PNP2@976|Bacteroidetes,1IKRW@117743|Flavobacteriia	976|Bacteroidetes	EN	Laminin G domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,MAM
k59_1762949_1	572480.Arnit_0938	2.53e-06	48.1	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2YMD0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ADP-L-glycero-D-manno-heptose-6-epimerase	waaD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_1762949_2	572480.Arnit_0939	1.81e-105	317.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2YMZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_349817_1	929558.SMGD1_1869	1.44e-157	451.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2YMCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_407099_1	1094466.KQS_02790	8.42e-54	170.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia,2NVW6@237|Flavobacterium	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_745556_1	1144313.PMI10_00661	4.93e-20	90.5	2DNIX@1|root,32XR6@2|Bacteria,4NU21@976|Bacteroidetes,1I3XV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_349820_1	929558.SMGD1_0326	7.58e-61	198.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2YMSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_407107_1	1347342.BN863_28300	1.81e-121	370.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1762971_1	1178825.ALIH01000007_gene1625	5.58e-84	258.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1198694_1	929558.SMGD1_2686	2.31e-34	128.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1198694_2	563040.Saut_1136	5.87e-51	174.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2YP0V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_864430_1	326298.Suden_1523	4.94e-20	83.6	2BQTZ@1|root,32JQR@2|Bacteria,1Q2FB@1224|Proteobacteria,431HI@68525|delta/epsilon subdivisions,2YS7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_864430_2	929558.SMGD1_0598	2.21e-77	243.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2YMKR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_582240_1	326298.Suden_1111	2.1e-96	291.0	COG2301@1|root,COG2301@2|Bacteria,1NUDQ@1224|Proteobacteria,42QUW@68525|delta/epsilon subdivisions,2YNZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_582240_2	1123326.JFBL01000015_gene2430	3.03e-05	44.7	COG2010@1|root,COG2010@2|Bacteria,1Q2E5@1224|Proteobacteria,42VHQ@68525|delta/epsilon subdivisions,2YQ7N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1317426_1	385682.AFSL01000087_gene731	6.64e-43	155.0	COG0364@1|root,COG0364@2|Bacteria,4NE59@976|Bacteroidetes,2FNER@200643|Bacteroidia,3XIQC@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_469737_2	1279017.AQYJ01000016_gene434	4.5e-87	264.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,465IU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_751106_1	411154.GFO_3285	2.38e-225	622.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_751106_2	411154.GFO_3286	7.2e-139	399.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_1599687_2	1123514.KB905899_gene1901	3.96e-75	243.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,4603G@72273|Thiotrichales	72273|Thiotrichales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1486208_1	1168067.JAGP01000001_gene1172	1.04e-92	278.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,460TG@72273|Thiotrichales	72273|Thiotrichales	G	HAD-superfamily subfamily IIA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k59_1486208_2	1122236.KB905142_gene501	9.94e-58	184.0	2EBKA@1|root,335KQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74390_1	1380600.AUYN01000009_gene1302	1.01e-70	229.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_74390_2	1178825.ALIH01000001_gene2553	5.36e-13	67.4	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,1HYJF@117743|Flavobacteriia	976|Bacteroidetes	F	COG1864 DNA RNA endonuclease G, NUC1	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
k59_1034013_1	76114.ebB24	3.95e-57	179.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,2KWMH@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_129956_1	298386.PBPRB0212	8.2e-229	640.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1XV3X@135623|Vibrionales	135623|Vibrionales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DbpA,Helicase_C
k59_129956_2	1283300.ATXB01000002_gene2696	3.89e-32	128.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XFKT@135618|Methylococcales	135618|Methylococcales	T	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9,TarH
k59_1317481_1	1565129.JSFF01000003_gene2228	1.93e-55	184.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,2QANV@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_469787_1	1380600.AUYN01000007_gene3403	6.89e-203	584.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_640761_1	1121931.AUHG01000011_gene1848	4.71e-109	321.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1HY2Y@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_1091080_1	563040.Saut_0562	2.75e-54	174.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,42R47@68525|delta/epsilon subdivisions,2YP8Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_1091080_2	563040.Saut_0563	1.26e-76	234.0	COG0299@1|root,COG0299@2|Bacteria,1N4NS@1224|Proteobacteria,42TSB@68525|delta/epsilon subdivisions,2YQGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Formyl transferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_1091080_3	929558.SMGD1_0670	6.05e-24	100.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2YMA5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_189138_1	411154.GFO_0804	3.13e-91	270.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189138_2	1121931.AUHG01000016_gene1078	5e-128	370.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_583831_2	1121931.AUHG01000011_gene2073	1.17e-87	266.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1HY3V@117743|Flavobacteriia	976|Bacteroidetes	M	mandelate racemase	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
k59_1430604_1	1123517.JOMR01000001_gene771	1.36e-57	211.0	COG2604@1|root,COG2604@2|Bacteria,1QAMT@1224|Proteobacteria,1SXPP@1236|Gammaproteobacteria,462H7@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,TPR_19
k59_1430604_2	90814.KL370891_gene686	1.02e-65	211.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_471609_1	411154.GFO_2880	3.71e-45	159.0	COG1524@1|root,COG3119@1|root,COG1524@2|Bacteria,COG3119@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_471609_2	1121931.AUHG01000011_gene1645	4.19e-117	340.0	COG1215@1|root,COG1215@2|Bacteria,4NFXI@976|Bacteroidetes,1HXPW@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_922101_1	1173024.KI912148_gene2685	2.93e-10	64.3	COG1215@1|root,COG1215@2|Bacteria,1FZYV@1117|Cyanobacteria,1JHMX@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferase family 21	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576	2.4.1.336	ko:K19003	ko00561,ko01100,map00561,map01100	-	R02689	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3
k59_640772_1	760154.Sulba_1006	5.78e-99	297.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42YRK@68525|delta/epsilon subdivisions,2YRM7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
k59_1770671_1	1121937.AUHJ01000001_gene600	4.23e-67	210.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1487913_1	1178825.ALIH01000006_gene1537	1.93e-47	158.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1487913_2	1380384.JADN01000008_gene1118	5.43e-39	135.0	2DZM8@1|root,32VDQ@2|Bacteria,4NSF0@976|Bacteroidetes,1I3WI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1487913_3	1121887.AUDK01000013_gene3316	1.71e-158	465.0	COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GGDEF,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
k59_1261350_1	545695.TREAZ_2442	5.92e-10	65.1	COG0643@1|root,COG0643@2|Bacteria,2J7QF@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c
k59_1543105_1	1397278.AYMV01000022_gene2086	6.47e-13	72.8	COG3970@1|root,COG3970@2|Bacteria,2GN7V@201174|Actinobacteria,4FREZ@85023|Microbacteriaceae	201174|Actinobacteria	S	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
k59_1543105_2	926559.JoomaDRAFT_1274	7.18e-157	464.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1HX1F@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde	-	-	1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220	-	R00264,R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_1543105_3	935837.JAEK01000040_gene3700	2.82e-77	244.0	COG3386@1|root,COG3386@2|Bacteria,1V1TK@1239|Firmicutes,4HG0A@91061|Bacilli,1ZAVX@1386|Bacillus	91061|Bacilli	G	SMP-30/Gluconolaconase/LRE-like region	yvrE	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
k59_1543105_4	1123073.KB899241_gene3063	2.98e-111	330.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,1RPIT@1236|Gammaproteobacteria,1X4XS@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
k59_1430629_1	1137281.D778_00610	1.51e-79	249.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1430630_1	323850.Shew_2570	3.62e-168	476.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,2Q8US@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1770695_1	563040.Saut_1053	8.16e-51	163.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2YP43@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_1770695_2	1172190.M947_00915	9.96e-39	131.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2YT6X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	DnaK suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_527326_1	1123518.ARWI01000001_gene484	4.35e-162	463.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,461TK@72273|Thiotrichales	72273|Thiotrichales	E	Peptidase family M28	-	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_810420_2	748247.AZKH_3249	5.82e-25	103.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,2KU79@206389|Rhodocyclales	206389|Rhodocyclales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_1714085_1	948106.AWZT01000036_gene1751	1.98e-79	246.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,1K1R3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
k59_1543140_1	1121931.AUHG01000010_gene46	1.47e-203	590.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,1HXAX@117743|Flavobacteriia	976|Bacteroidetes	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_1487960_1	411154.GFO_0268	8.76e-81	241.0	COG0735@1|root,COG0735@2|Bacteria,4NQND@976|Bacteroidetes,1I92X@117743|Flavobacteriia	976|Bacteroidetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1319275_2	59374.Fisuc_2059	5.13e-21	92.4	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_357152_1	1123514.KB905899_gene698	2.03e-72	234.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,45ZYF@72273|Thiotrichales	72273|Thiotrichales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1543152_1	1336233.JAEH01000015_gene3235	1.26e-87	268.0	COG0845@1|root,COG0845@2|Bacteria,1P5GT@1224|Proteobacteria,1S7A6@1236|Gammaproteobacteria,2Q8V8@267890|Shewanellaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
k59_1035770_1	1178825.ALIH01000004_gene2897	1.22e-50	171.0	COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,1IIKI@117743|Flavobacteriia	976|Bacteroidetes	M	Sucrose synthase	gmhA	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
k59_1035770_2	1250005.PHEL85_1214	3.09e-48	159.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,1I213@117743|Flavobacteriia,3VXEV@52959|Polaribacter	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
k59_752797_1	411154.GFO_3446	3.37e-164	483.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1HWWX@117743|Flavobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
k59_1091180_1	864702.OsccyDRAFT_1347	3.37e-38	146.0	COG1216@1|root,COG3210@1|root,COG4995@1|root,COG1216@2|Bacteria,COG3210@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Glycos_transf_2,Haemagg_act
k59_1373830_2	1121931.AUHG01000017_gene1616	2.03e-150	427.0	COG2819@1|root,COG2819@2|Bacteria,4NGAG@976|Bacteroidetes,1HZR3@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	CBM_20,Esterase
k59_1373830_3	760192.Halhy_0227	1.32e-51	181.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IT3V@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE
k59_245767_1	323850.Shew_2239	3.64e-41	143.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,2Q8YG@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
k59_245767_2	637905.SVI_2786	6.72e-11	57.4	291R7@1|root,31H60@2|Bacteria,1QEV6@1224|Proteobacteria,1TBRW@1236|Gammaproteobacteria,2QD31@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_357201_1	1380600.AUYN01000007_gene3163	4.18e-127	384.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	malZ	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_18129_1	987059.RBXJA2T_14051	2.33e-51	172.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VMPX@28216|Betaproteobacteria,1KIXZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_810508_2	944547.ABLL_1732	1.08e-07	56.6	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,42T4C@68525|delta/epsilon subdivisions,2YPPT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_810508_3	709032.Sulku_0963	2.14e-29	115.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42YAR@68525|delta/epsilon subdivisions,2YR9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1543209_1	1565129.JSFF01000001_gene1124	1.55e-105	324.0	COG2067@1|root,COG3637@1|root,COG2067@2|Bacteria,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria,2QA00@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
k59_1770818_1	1172190.M947_08055	2.58e-52	183.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,43BUD@68525|delta/epsilon subdivisions,2YTD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_76417_1	566466.NOR53_1945	4.32e-59	211.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1J88E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
k59_1261508_1	1122180.Lokhon_02951	1.38e-17	77.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,2P8YJ@245186|Loktanella	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_1261508_2	45351.EDO25426	2.11e-60	188.0	COG0649@1|root,KOG2870@2759|Eukaryota,38E8K@33154|Opisthokonta,3BADS@33208|Metazoa	33154|Opisthokonta	C	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa
k59_1319363_1	929558.SMGD1_2630	6.07e-62	195.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2YMH3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_1319363_2	929558.SMGD1_2629	1.1e-21	92.4	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_976051_1	1380384.JADN01000006_gene2671	6.37e-91	300.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SBBP,SprB
k59_976051_2	1380600.AUYN01000009_gene1147	3.03e-15	73.9	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
k59_866322_1	351348.Maqu_0080	1.54e-115	344.0	COG1160@1|root,COG1160@2|Bacteria,1QU8G@1224|Proteobacteria,1T3BC@1236|Gammaproteobacteria,465YW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k59_189290_1	517418.Ctha_1504	2.49e-35	131.0	COG4992@1|root,COG4992@2|Bacteria,1FDGR@1090|Chlorobi	1090|Chlorobi	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_1373880_2	1270193.JARP01000003_gene1965	2.74e-29	115.0	COG0438@1|root,COG0438@2|Bacteria,4PPF4@976|Bacteroidetes,1IKKG@117743|Flavobacteriia,2NT2D@237|Flavobacterium	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1091253_1	1392490.JHZX01000001_gene544	4.13e-30	108.0	2E0NT@1|root,32W7U@2|Bacteria,4NTP9@976|Bacteroidetes,1I4V2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1091253_2	1144313.PMI10_03697	1.6e-70	218.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,1I0Q1@117743|Flavobacteriia,2NS8W@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1430768_1	929558.SMGD1_2275	7.01e-65	200.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2YPZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	transport protein	tolR	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1430768_2	929558.SMGD1_2274	3.73e-32	116.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2YNC3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	MotA TolQ ExbB proton channel family	tolQ	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_1770841_1	1123518.ARWI01000001_gene488	7.13e-74	234.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,1RR6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_1035878_1	1279009.ADICEAN_03514	1.72e-55	191.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
k59_656845_1	1123518.ARWI01000001_gene2030	6.46e-43	159.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,1SCWE@1236|Gammaproteobacteria,4616E@72273|Thiotrichales	72273|Thiotrichales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7
k59_1389562_1	411154.GFO_3340	8.06e-32	114.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_1389562_2	411154.GFO_3339	2.27e-83	254.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1HWZ8@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1164048_1	929558.SMGD1_2623	3.61e-66	222.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_1558924_1	1380600.AUYN01000009_gene1143	3.92e-26	103.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia	976|Bacteroidetes	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_263786_2	563040.Saut_0628	1.9e-69	216.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2YNB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	abc transporter atp-binding protein	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_884187_1	1123228.AUIH01000011_gene2053	5.75e-54	180.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XHR9@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_1338045_1	1123234.AUKI01000017_gene2493	1.13e-20	92.4	COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_1166074_1	1046627.BZARG_12	1.12e-116	356.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_35328_1	105425.BBPL01000018_gene37	9.11e-77	236.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,2NHYY@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_374958_2	929558.SMGD1_1723	5.98e-59	189.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2YPTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3786 conserved	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_658966_1	572480.Arnit_0006	3.49e-102	296.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,42RYN@68525|delta/epsilon subdivisions,2YP3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_374966_1	983544.Lacal_1591	8.98e-44	149.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1560995_1	1178825.ALIH01000019_gene1223	1.15e-71	228.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1560995_2	1178825.ALIH01000019_gene1222	3.51e-15	72.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1675568_1	1123228.AUIH01000002_gene1531	1.39e-89	289.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XIDI@135619|Oceanospirillales	135619|Oceanospirillales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1731896_1	1168067.JAGP01000001_gene1067	1.17e-58	201.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,45ZS9@72273|Thiotrichales	72273|Thiotrichales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_770537_1	572480.Arnit_0844	2.85e-122	370.0	COG2199@1|root,COG2200@1|root,COG3829@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3829@2|Bacteria,1NQKX@1224|Proteobacteria,43CBB@68525|delta/epsilon subdivisions,2YTB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	nitrogen fixation positive	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_1052407_1	1123518.ARWI01000001_gene2232	2.46e-135	385.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,45ZQ2@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_1052407_2	553385.JEMF01000007_gene1835	6.32e-06	47.4	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XH6T@135619|Oceanospirillales	135619|Oceanospirillales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_717768_1	317025.Tcr_1461	1.17e-66	215.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RPFX@1236|Gammaproteobacteria,4605C@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1789060_1	1565129.JSFF01000004_gene3187	4.28e-10	58.9	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,2QAC6@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812	DHDPS
k59_1789060_2	323850.Shew_1849	7.11e-123	360.0	COG3317@1|root,COG3317@2|Bacteria,1MUUK@1224|Proteobacteria,1RN2X@1236|Gammaproteobacteria,2Q9G5@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045229,GO:0061024,GO:0071709,GO:0071840,GO:0071944,GO:0098552,GO:0098796,GO:1990063	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k59_320001_1	572480.Arnit_2272	1.26e-126	364.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k59_320001_2	572480.Arnit_2271	1.5e-29	109.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42M21@68525|delta/epsilon subdivisions,2YRFQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_35406_1	640081.Dsui_1961	7.9e-10	56.2	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_35406_2	1046625.AFQY01000006_gene2073	1.62e-55	183.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,3NII4@468|Moraxellaceae	1236|Gammaproteobacteria	M	UDP-glucose 4-epimerase	galE	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0003978,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901575,GO:1901576	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2076,iPC815.YPO1139,iSF_1195.SF0545,iSFxv_1172.SFxv_0601,iS_1188.S0553,iYL1228.KPN_00773,ic_1306.c2560	Epimerase,GDP_Man_Dehyd
k59_1506779_1	323850.Shew_1524	3.93e-112	325.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,2Q9MQ@267890|Shewanellaceae	1236|Gammaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_1506779_2	323850.Shew_1523	3.17e-60	187.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,2QBY4@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM thioesterase superfamily protein	ybgC	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_0747,iSDY_1059.SDY_0684	4HBT
k59_1279408_1	1894.JOER01000047_gene1538	1.09e-05	50.8	COG1309@1|root,COG1309@2|Bacteria,2GMZ0@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
k59_94220_1	926562.Oweho_1807	7e-55	194.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_489481_1	1380600.AUYN01000009_gene1716	5.18e-222	615.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1391701_1	1355368.JART01000019_gene1063	2.01e-15	71.2	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,42THN@68525|delta/epsilon subdivisions,2YPTV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
k59_1391701_2	572480.Arnit_0759	1.09e-63	199.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42R9R@68525|delta/epsilon subdivisions,2YTR4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	3' exoribonuclease, RNase T-like	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_992356_1	945713.IALB_3162	1.53e-10	61.2	COG0442@1|root,COG0442@2|Bacteria	2|Bacteria	J	prolyl-tRNA aminoacylation	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.proS	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_992356_2	945713.IALB_3164	3.57e-55	188.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_1620314_1	572480.Arnit_1974	5.24e-130	394.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_992371_1	1209072.ALBT01000038_gene2432	6.82e-21	97.4	COG2885@1|root,COG3266@1|root,COG4547@1|root,COG4935@1|root,COG5384@1|root,COG2885@2|Bacteria,COG3266@2|Bacteria,COG4547@2|Bacteria,COG4935@2|Bacteria,COG5384@2|Bacteria	2|Bacteria	J	extracellular matrix structural constituent	atl	-	3.2.1.96,3.5.1.28	ko:K13714	-	-	-	-	ko00000,ko01000	-	GH73	-	CHU_C,CobT_C,Glucosaminidase,SH3_8,SPOR,TSP_3,VWA
k59_1506823_1	985255.APHJ01000043_gene435	6.68e-77	237.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HWM7@117743|Flavobacteriia,2P78D@244698|Gillisia	976|Bacteroidetes	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_375069_1	1137281.D778_02096	2.49e-100	317.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NJY0@976|Bacteroidetes,1HZX6@117743|Flavobacteriia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
k59_770600_1	1121931.AUHG01000012_gene2595	1.06e-38	129.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_35465_1	751994.AGIG01000017_gene51	2.22e-99	297.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RR72@1236|Gammaproteobacteria,1J4CQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	dctP	GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015740,GO:0015849,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_1338191_1	411154.GFO_3460	3.31e-35	126.0	COG1011@1|root,COG1011@2|Bacteria,4NHRZ@976|Bacteroidetes,1HZUS@117743|Flavobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1338191_2	1121931.AUHG01000010_gene471	4.46e-60	189.0	COG2930@1|root,COG2930@2|Bacteria,4NP71@976|Bacteroidetes,1I20I@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Family of	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_207205_1	1380600.AUYN01000009_gene976	5.04e-104	309.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_207205_2	1380600.AUYN01000009_gene975	2.18e-110	320.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1I1D8@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_1279480_1	1121931.AUHG01000012_gene2877	3.14e-91	293.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1109374_1	1172190.M947_06630	1.6e-83	248.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2YNVK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k59_1109374_2	563040.Saut_0372	1.35e-78	235.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2YPFW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_1561137_1	1123514.KB905899_gene1970	8.1e-25	101.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,46175@72273|Thiotrichales	72273|Thiotrichales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_992421_1	582744.Msip34_2472	1.11e-19	89.0	COG0715@1|root,COG5001@1|root,COG0715@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,NMT1,PAS_3,PAS_9
k59_992421_2	1150621.SMUL_1248	1.73e-30	122.0	COG4389@1|root,COG4389@2|Bacteria,1MWEH@1224|Proteobacteria,42YI9@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Site-specific recombinase	gcr	-	-	-	-	-	-	-	-	-	-	-	SpecificRecomb
k59_1109385_1	90814.KL370891_gene219	2.33e-84	255.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,46208@72273|Thiotrichales	72273|Thiotrichales	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k59_659145_2	985255.APHJ01000026_gene2369	8.7e-13	68.2	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1HX64@117743|Flavobacteriia,2P5FQ@244698|Gillisia	976|Bacteroidetes	J	Formyl transferase, C-terminal domain	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k59_149518_1	90814.KL370891_gene1915	1.66e-113	341.0	COG0531@1|root,COG0531@2|Bacteria,1QVWZ@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	ybaT	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009268,GO:0009628,GO:0010035,GO:0010038,GO:0016020,GO:0042221,GO:0044464,GO:0046688,GO:0050896,GO:0071944,GO:0097501,GO:1990169	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_1620377_1	991.IW20_15115	1.64e-64	213.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
k59_149521_1	1178825.ALIH01000014_gene1948	8.82e-129	375.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1HY45@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
k59_770676_1	1172190.M947_07040	1.55e-116	368.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_320144_1	929558.SMGD1_2365	2.77e-70	237.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42YBF@68525|delta/epsilon subdivisions,2YRIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_600591_1	1123228.AUIH01000034_gene2771	7.5e-77	238.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1XI33@135619|Oceanospirillales	135619|Oceanospirillales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_94351_2	323850.Shew_2690	1.4e-29	116.0	COG4774@1|root,COG4774@2|Bacteria,1R085@1224|Proteobacteria,1RQTH@1236|Gammaproteobacteria,2QA40@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_544640_1	1380600.AUYN01000009_gene1889	8.22e-116	340.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_544640_2	1380600.AUYN01000009_gene1890	7.37e-244	674.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_544640_3	1492737.FEM08_30670	1.34e-77	238.0	COG1209@1|root,COG1209@2|Bacteria,4NF32@976|Bacteroidetes,1HZD0@117743|Flavobacteriia	976|Bacteroidetes	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
k59_375155_1	929558.SMGD1_2325	8.19e-77	241.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2YNFF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_375155_2	563040.Saut_1427	3.63e-45	147.0	COG4627@1|root,COG4627@2|Bacteria,1NHR6@1224|Proteobacteria,42VA4@68525|delta/epsilon subdivisions,2YQEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_375176_1	1172190.M947_04665	2.13e-83	255.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2YMM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1789261_1	1178825.ALIH01000001_gene2547	8.07e-104	309.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1HXFU@117743|Flavobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1506967_1	1121405.dsmv_2773	1.02e-74	233.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2MHYE@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_1279592_1	400668.Mmwyl1_0219	8.75e-10	61.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XHQA@135619|Oceanospirillales	135619|Oceanospirillales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k59_1279592_2	76114.ebA7094	8.99e-18	81.6	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,2VI3P@28216|Betaproteobacteria,2KUKX@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA ligase	dnaL	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_829631_1	746697.Aeqsu_1429	7.51e-93	303.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1052583_1	411154.GFO_0431	4.73e-49	166.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_1052583_2	1121931.AUHG01000015_gene1174	7.27e-46	151.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
k59_1506990_1	1232410.KI421421_gene3557	6.38e-61	200.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43RYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_717992_1	326298.Suden_0648	2.04e-61	199.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2YP3D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_1052595_1	1380600.AUYN01000007_gene3256	4.06e-150	440.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1052595_2	1178825.ALIH01000003_gene2149	7.94e-77	236.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1561262_2	1137281.D778_01364	1.48e-50	162.0	2CP87@1|root,32SIN@2|Bacteria,4NS9S@976|Bacteroidetes,1I3VG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1561262_3	504487.JCM19302_3341	4.02e-112	327.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_717998_1	1123228.AUIH01000004_gene1114	3.45e-81	244.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales	135619|Oceanospirillales	S	colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_717998_2	981223.AIED01000017_gene930	4.87e-15	73.9	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,3NJRY@468|Moraxellaceae	1236|Gammaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125	GATase_6,Pribosyltran
k59_1391909_1	1123514.KB905901_gene17	1.63e-80	249.0	2F0VY@1|root,33TXM@2|Bacteria,1NVBB@1224|Proteobacteria,1SNJU@1236|Gammaproteobacteria,4629H@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_432953_2	326298.Suden_0309	1.55e-27	102.0	COG1605@1|root,COG1605@2|Bacteria,1N6UE@1224|Proteobacteria,42UUU@68525|delta/epsilon subdivisions,2YQ49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
k59_320239_1	1121931.AUHG01000010_gene71	1e-59	192.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_938773_1	1197477.IA57_00950	3.59e-101	318.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_938773_2	1380600.AUYN01000009_gene1610	1.85e-64	203.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1I2C8@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1228336_2	83406.HDN1F_31750	5.91e-22	87.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria,1J6SP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	rsbV	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
k59_1295857_1	1123514.KB905899_gene1224	3.82e-103	316.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_1354762_1	323850.Shew_2051	3.27e-102	319.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,2QAQ2@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	fadE	-	1.3.8.7	ko:K00249,ko:K06445	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
k59_1354781_1	1122225.AULQ01000005_gene2581	4.97e-110	333.0	COG3291@1|root,COG4085@1|root,COG3291@2|Bacteria,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes,1HWVQ@117743|Flavobacteriia	976|Bacteroidetes	F	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
k59_1354781_2	1380600.AUYN01000006_gene642	9.21e-35	127.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HXFT@117743|Flavobacteriia	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_1008874_1	1123514.KB905899_gene576	9.87e-09	53.1	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	cycM	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1008874_2	90814.KL370891_gene1497	1.34e-51	164.0	COG2863@1|root,COG2863@2|Bacteria,1NGKI@1224|Proteobacteria	1224|Proteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_787691_1	1453498.LG45_06195	2.67e-21	93.2	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia,2NUB9@237|Flavobacterium	976|Bacteroidetes	G	Maltose phosphorylase	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_787691_2	641526.ADIWIN_1173	4.44e-81	260.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208,ko:K21575	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_165007_1	497321.C664_16350	7.04e-43	142.0	COG2010@1|root,COG2010@2|Bacteria,1N7JC@1224|Proteobacteria,2VVUW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_165007_2	497321.C664_16355	5.34e-37	132.0	2EFR7@1|root,339H9@2|Bacteria,1NDDC@1224|Proteobacteria,2W3FJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1749079_1	1380600.AUYN01000009_gene1769	2e-52	176.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_1126004_1	435591.BDI_0509	2.02e-05	47.8	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FXAU@200643|Bacteroidia,231GG@171551|Porphyromonadaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,AAA_16,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y
k59_1126004_2	563040.Saut_1905	1.34e-62	205.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2YMDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_336647_1	929558.SMGD1_1506	4.98e-184	519.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2YN1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_336647_2	326298.Suden_0074	9.35e-22	91.3	COG0124@1|root,COG0124@2|Bacteria,1QUJQ@1224|Proteobacteria,42NX2@68525|delta/epsilon subdivisions,2YN2F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisZ	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_His
k59_110986_1	326298.Suden_1754	1.67e-52	174.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2YMUH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iIT341.HP0921	Gp_dh_C,Gp_dh_N
k59_110986_2	929558.SMGD1_1786	2.17e-76	233.0	COG1057@1|root,COG1057@2|Bacteria,1NG4J@1224|Proteobacteria,42P0F@68525|delta/epsilon subdivisions,2YMQR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,RsfS
k59_110986_3	326298.Suden_1756	5.63e-35	121.0	COG0799@1|root,COG0799@2|Bacteria,1RCJN@1224|Proteobacteria,42TWB@68525|delta/epsilon subdivisions,2YPU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_559924_1	985255.APHJ01000021_gene1571	1.94e-110	325.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1HWK6@117743|Flavobacteriia,2P681@244698|Gillisia	976|Bacteroidetes	H	Molybdenum Cofactor Synthesis C	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_559924_2	985255.APHJ01000021_gene1570	4.29e-22	92.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia,2P68D@244698|Gillisia	976|Bacteroidetes	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
k59_165025_1	1121931.AUHG01000010_gene40	3.21e-106	315.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_1523585_1	411154.GFO_1554	5.2e-101	316.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1HXS8@117743|Flavobacteriia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165037_1	1392488.JHZY01000002_gene467	1.86e-99	311.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia,2XI9W@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_675798_1	1484460.JSWG01000010_gene3163	5.67e-71	228.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_1749125_1	616991.JPOO01000001_gene4432	7.82e-84	263.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1I02T@117743|Flavobacteriia	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_1523615_1	572480.Arnit_2650	2.49e-130	385.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_111037_1	764299.STRIC_1871	1.12e-07	52.0	COG2503@1|root,COG2503@2|Bacteria	2|Bacteria	M	HAD superfamily, subfamily IIIB (Acid phosphatase)	hel	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
k59_50755_1	1137281.D778_02039	3.01e-68	225.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_675822_1	929558.SMGD1_0578	1.7e-146	436.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1749161_1	1150621.SMUL_2771	0.000151	48.9	COG0810@1|root,COG0810@2|Bacteria,1NFMG@1224|Proteobacteria,42UAW@68525|delta/epsilon subdivisions,2YQ5E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1463766_1	1487923.DP73_11115	1.48e-17	82.4	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia,263SI@186807|Peptococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	abiGI	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
k59_50771_1	1392488.JHZY01000004_gene2329	1.18e-20	92.8	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1HY9Z@117743|Flavobacteriia,2XI0W@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_50771_2	1123037.AUDE01000006_gene1124	6.95e-87	259.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1HZ1F@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_448411_1	1123228.AUIH01000006_gene2172	1.12e-33	125.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XIFG@135619|Oceanospirillales	135619|Oceanospirillales	E	in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_448411_2	1123228.AUIH01000006_gene2171	8.09e-42	139.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XK7A@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_1463776_1	929558.SMGD1_1311	2.8e-51	166.0	COG3829@1|root,COG3829@2|Bacteria,1NG3B@1224|Proteobacteria,43AE4@68525|delta/epsilon subdivisions,2YT0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_505701_1	1121931.AUHG01000018_gene1397	3.55e-121	354.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,1HXXC@117743|Flavobacteriia	976|Bacteroidetes	S	sulfatase	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
k59_505701_2	411154.GFO_0284	2.08e-188	528.0	COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,1HYNH@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
k59_505701_3	411154.GFO_0283	7.26e-57	177.0	COG2343@1|root,COG2343@2|Bacteria,4NSIC@976|Bacteroidetes,1I3X7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
k59_615775_1	929558.SMGD1_2859	1.66e-109	330.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_1749179_1	396588.Tgr7_0341	1.17e-28	107.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria,1WY1W@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k59_1749179_2	765913.ThidrDRAFT_1494	7.23e-11	62.4	2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1228492_1	1280390.CBQR020000009_gene198	1.16e-08	58.5	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,26QGU@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA3	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_1523674_1	1415778.JQMM01000001_gene1922	3.7e-125	388.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1J4G0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_277675_1	572480.Arnit_0192	1.78e-48	164.0	COG4974@1|root,COG4974@2|Bacteria,1QUFQ@1224|Proteobacteria,43CG3@68525|delta/epsilon subdivisions,2YTMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_448434_1	1197477.IA57_01060	4.64e-188	557.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1068331_1	1121374.KB891575_gene1581	2.32e-20	90.1	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1068331_2	1123228.AUIH01000022_gene3125	4.82e-62	199.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RQ5E@1236|Gammaproteobacteria,1XJG4@135619|Oceanospirillales	135619|Oceanospirillales	NT	COG1352 Methylase of chemotaxis methyl-accepting proteins	-	-	2.1.1.80	ko:K00575,ko:K02661	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	-	-	-	CheR,CheR_N
k59_336807_1	1046627.BZARG_1745	4.1e-74	228.0	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,1I1FQ@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
k59_336807_2	1484460.JSWG01000009_gene567	1.29e-49	164.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_223473_1	398579.Spea_3884	3.27e-114	347.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,2QA2S@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_1009049_1	985255.APHJ01000017_gene2166	3.61e-73	237.0	COG0028@1|root,COG0028@2|Bacteria,4NH3H@976|Bacteroidetes,1HYIZ@117743|Flavobacteriia,2P758@244698|Gillisia	976|Bacteroidetes	EH	Thiamine pyrophosphate enzyme, central domain	poxB	-	1.2.5.1,2.2.1.6	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03145,R04672,R04673,R08648	RC00027,RC00106,RC00860,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_50854_1	1537917.JU82_00150	2.73e-22	92.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42UQ6@68525|delta/epsilon subdivisions,2YQ4Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM PAS fold-3 domain protein	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
k59_50854_2	1537917.JU82_00190	5.1e-98	292.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42P1N@68525|delta/epsilon subdivisions,2YTRU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_842489_1	411154.GFO_1455	2.31e-47	168.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1HYC9@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
k59_842489_2	1121931.AUHG01000012_gene2711	4.18e-56	186.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1126202_1	1123514.KB905899_gene1470	2.21e-33	121.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,4617R@72273|Thiotrichales	72273|Thiotrichales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k59_1126202_2	90814.KL370891_gene658	7.93e-26	99.4	COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,4637D@72273|Thiotrichales	72273|Thiotrichales	KNU	Anti-sigma-28 factor FlgM	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
k59_1126202_4	90814.KL370891_gene656	1.99e-75	231.0	2E62S@1|root,330RV@2|Bacteria,1N7P9@1224|Proteobacteria,1SHBI@1236|Gammaproteobacteria,461I4@72273|Thiotrichales	72273|Thiotrichales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_560128_1	1123514.KB905899_gene2033	1.35e-58	192.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,462MK@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1692359_1	1163671.JAGI01000001_gene253	1.96e-22	92.4	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,36JKF@31979|Clostridiaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_1692359_2	319236.JCM19294_2894	1.47e-30	112.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,1HX5C@117743|Flavobacteriia,3HJT5@363408|Nonlabens	976|Bacteroidetes	H	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
k59_1749306_1	572480.Arnit_2856	3.99e-127	372.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2YMRI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0134	DAHP_synth_2
k59_505841_1	983545.Glaag_3924	8.01e-52	179.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,464KY@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_787929_1	411154.GFO_1825	2.95e-104	304.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,1HYZT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_615904_1	373903.Hore_01200	4.31e-42	150.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WACR@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_1523800_1	1208321.D104_11640	2.04e-31	118.0	COG0406@1|root,COG0406@2|Bacteria,1RA6X@1224|Proteobacteria,1S57C@1236|Gammaproteobacteria,1XNX8@135619|Oceanospirillales	135619|Oceanospirillales	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
k59_505848_1	1336233.JAEH01000030_gene258	1.61e-129	380.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,2Q94K@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k59_560148_1	411154.GFO_1637	1.05e-31	120.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1HX3N@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
k59_560148_2	411154.GFO_1638	1.48e-55	181.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1182971_1	323850.Shew_1951	5.78e-107	318.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,2Q8PZ@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1408397_2	90814.KL370891_gene773	2.44e-156	448.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,460WJ@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM DNA polymerase III, delta	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k59_1408397_3	1182590.BN5_02567	3.1e-43	148.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1YE7Y@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c13120,ic_1306.c1370	Thymidylate_kin
k59_1070921_1	765912.Thimo_2979	1.81e-11	64.7	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,1WVZ8@135613|Chromatiales	135613|Chromatiales	S	PFAM NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
k59_845171_1	485918.Cpin_3951	3.3e-201	587.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1INVS@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1070927_1	1123514.KB905899_gene1516	2.17e-125	358.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,4624C@72273|Thiotrichales	72273|Thiotrichales	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k59_1185654_1	1565129.JSFF01000008_gene2694	1.72e-21	89.4	COG2258@1|root,COG2258@2|Bacteria,1PBZ2@1224|Proteobacteria,1S8N6@1236|Gammaproteobacteria,2QCAW@267890|Shewanellaceae	1236|Gammaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k59_1185654_2	314265.R2601_16330	4.38e-16	79.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_279763_1	1237149.C900_00291	3.55e-54	173.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
k59_1185659_1	425104.Ssed_3032	2.99e-184	538.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,2Q8WR@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_1466853_2	32024.JMTI01000036_gene794	1.77e-20	86.7	COG3829@1|root,COG3829@2|Bacteria,1NG3B@1224|Proteobacteria,43AE4@68525|delta/epsilon subdivisions,2YT0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
k59_790583_1	1178825.ALIH01000002_gene1112	1.77e-16	79.3	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
k59_790583_2	1178825.ALIH01000002_gene1113	6.56e-54	189.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
k59_1579537_1	1286106.MPL1_13157	3.42e-71	228.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1S0D6@1236|Gammaproteobacteria,461VJ@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferase 4-like	-	-	-	ko:K13004	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_2,Glycos_transf_1
k59_1579537_2	485916.Dtox_4095	5.87e-13	70.5	COG0110@1|root,COG0110@2|Bacteria,1VHA7@1239|Firmicutes,24T1B@186801|Clostridia	186801|Clostridia	M	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
k59_1705666_1	1408473.JHXO01000013_gene608	7.12e-151	462.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_406612_1	1565129.JSFF01000001_gene1109	1.14e-41	144.0	COG0564@1|root,COG0564@2|Bacteria,1R4IN@1224|Proteobacteria,1S0WR@1236|Gammaproteobacteria,2QAW1@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM pseudouridine synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_406612_2	1565129.JSFF01000001_gene1108	8.55e-67	220.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,2QAY4@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k59_67770_1	1089548.KI783301_gene265	5.06e-78	235.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,3WFJR@539002|Bacillales incertae sedis	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
k59_575991_1	411154.GFO_1547	2e-61	199.0	COG0834@1|root,COG0834@2|Bacteria,4NEQQ@976|Bacteroidetes,1I027@117743|Flavobacteriia	976|Bacteroidetes	ET	Ligand-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Lig_chan,SBP_bac_3
k59_123717_1	929558.SMGD1_2235	2.99e-88	275.0	COG0068@1|root,COG0068@2|Bacteria,1NS2D@1224|Proteobacteria,42WS0@68525|delta/epsilon subdivisions,2YQAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1310901_1	504487.JCM19302_503	7.81e-105	310.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1HX1Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_1422923_1	367737.Abu_1934	6.2e-17	79.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2YN61@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_1422923_3	929558.SMGD1_0953	7.1e-07	47.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2YQBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Redox-active disulfide protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_914515_1	395494.Galf_1131	3.88e-45	172.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WBU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_4,PAS_9
k59_914517_1	1380600.AUYN01000010_gene883	2.51e-09	57.4	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,1I0QJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,TPR_2,TPR_8
k59_914517_2	742817.HMPREF9449_02038	1.74e-99	292.0	COG1014@1|root,COG1014@2|Bacteria,4NGWJ@976|Bacteroidetes,2FNG6@200643|Bacteroidia,22X34@171551|Porphyromonadaceae	976|Bacteroidetes	C	2-oxoglutarate ferredoxin oxidoreductase subunit gamma	porG	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_914517_3	927658.AJUM01000042_gene1758	3.15e-127	368.0	COG1013@1|root,COG1013@2|Bacteria,4NDWF@976|Bacteroidetes,2FP3C@200643|Bacteroidia,3XJ0W@558415|Marinilabiliaceae	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorA	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_1083405_1	85643.Tmz1t_1260	7.89e-115	346.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,2KUNY@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
k59_802264_1	1168067.JAGP01000001_gene934	4.18e-299	824.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,46011@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_1365773_1	504487.JCM19302_292	2.46e-69	214.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1HX5Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	with different specificities (Related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1365773_2	1046627.BZARG_2456	8.2e-45	149.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1I1AR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_1762473_1	411154.GFO_1787	6.54e-143	429.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_1310917_1	1123514.KB905899_gene1142	6.56e-102	308.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,1RZVF@1236|Gammaproteobacteria,46349@72273|Thiotrichales	72273|Thiotrichales	M	NlpB/DapX lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_18
k59_1310917_2	1123518.ARWI01000001_gene2410	2.51e-58	202.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,45ZSY@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1593314_1	411154.GFO_3207	1.56e-29	108.0	COG4232@1|root,COG4232@2|Bacteria,4PMSY@976|Bacteroidetes,1IJZ6@117743|Flavobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_1593314_2	411154.GFO_3206	2.49e-245	692.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HX6P@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1140122_1	391937.NA2_08766	1.56e-78	241.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,43NHA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_1194189_1	411154.GFO_0155	7.66e-20	86.7	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1194189_2	983544.Lacal_1359	4.2e-68	210.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1I2U1@117743|Flavobacteriia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_237625_1	323850.Shew_1600	4.82e-130	376.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,2QAEW@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695	FA_synthesis
k59_293587_1	572480.Arnit_0927	1.45e-105	318.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2YMR5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_802280_1	1565129.JSFF01000002_gene3479	9.86e-09	54.7	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,1RNBZ@1236|Gammaproteobacteria,2Q9S1@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	PFAM dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
k59_802280_2	398579.Spea_0742	2.09e-88	268.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,2Q9Y5@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region	ldhA	GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006067,GO:0006082,GO:0006083,GO:0006089,GO:0006090,GO:0006091,GO:0006103,GO:0006105,GO:0006113,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008720,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015942,GO:0015980,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019318,GO:0019362,GO:0019637,GO:0019660,GO:0019664,GO:0019666,GO:0019693,GO:0019752,GO:0032787,GO:0034308,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0050896,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0070404,GO:0071704,GO:0072521,GO:0072524,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901615	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_1649,iPC815.YPO2329,iSFV_1184.SFV_1805,iSF_1195.SF1814,iSFxv_1172.SFxv_2031,iS_1188.S1459	2-Hacid_dh,2-Hacid_dh_C
k59_857912_1	709032.Sulku_1290	2.61e-50	184.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42YBF@68525|delta/epsilon subdivisions,2YRIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_802294_1	990285.RGCCGE502_07961	3.66e-18	85.5	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,4BAYB@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_1479665_1	572480.Arnit_0426	4.57e-80	248.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1479665_2	944547.ABLL_2605	4.93e-11	62.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2YMZM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1253299_1	90814.KL370891_gene1759	5.86e-89	275.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,45ZP3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_10753_1	1174684.EBMC1_07970	1.36e-21	89.4	COG3498@1|root,COG3498@2|Bacteria,1Q8HB@1224|Proteobacteria,2UACK@28211|Alphaproteobacteria,2K502@204457|Sphingomonadales	204457|Sphingomonadales	S	Phage tail tube protein FII	-	-	-	ko:K06908	-	-	-	-	ko00000	-	-	-	Phage_tube
k59_10753_2	1121939.L861_08970	1.55e-40	146.0	COG3497@1|root,COG3497@2|Bacteria,1MW1V@1224|Proteobacteria,1RNUT@1236|Gammaproteobacteria,1XP3Z@135619|Oceanospirillales	135619|Oceanospirillales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_181070_1	1123518.ARWI01000001_gene1741	3.13e-143	412.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,45ZVT@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_181070_2	1123518.ARWI01000001_gene1740	4.22e-198	552.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,46181@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_181070_3	1123518.ARWI01000001_gene1739	2.14e-98	286.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,460N6@72273|Thiotrichales	72273|Thiotrichales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1083449_1	317025.Tcr_0854	8.29e-48	170.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria,461QI@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_1083449_2	317025.Tcr_0853	7.04e-277	766.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,461IV@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
k59_293613_1	929562.Emtol_4145	3.9e-83	256.0	COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,47NMZ@768503|Cytophagia	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_293613_2	1121912.AUHD01000005_gene1632	2.5e-159	461.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,1HZZG@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_857946_1	1506583.JQJY01000002_gene1292	3.25e-10	61.2	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,1I42J@117743|Flavobacteriia,2NUWH@237|Flavobacterium	976|Bacteroidetes	S	PFAM MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
k59_857946_2	1282356.H045_12925	2.95e-44	154.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1YPJE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	chemotaxis protein	chev-2	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_1479689_1	317025.Tcr_1851	1.36e-41	157.0	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,463M4@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_802313_1	1197477.IA57_01360	8.02e-78	237.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,1I2IW@117743|Flavobacteriia	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_802313_2	1178825.ALIH01000001_gene2687	1.15e-124	360.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_123799_1	1454202.PPBDW_20023___1	1.04e-20	94.0	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1XU1I@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
k59_970086_1	411154.GFO_0766	2.46e-59	202.0	COG0495@1|root,COG0495@2|Bacteria,4PKSC@976|Bacteroidetes,1IJEG@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
k59_1593374_1	1123518.ARWI01000001_gene97	2.8e-10	56.2	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	yfhL	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_1593374_2	1123518.ARWI01000001_gene98	7.98e-42	142.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1S6AG@1236|Gammaproteobacteria,462B4@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
k59_1083458_1	1120951.AUBG01000001_gene1015	0.000121	52.4	COG1572@1|root,COG1572@2|Bacteria,4P4S8@976|Bacteroidetes,1I9MJ@117743|Flavobacteriia	976|Bacteroidetes	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1140180_1	929558.SMGD1_2607	2.96e-98	301.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2YN14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
k59_349439_2	929558.SMGD1_1298	3.34e-62	197.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42R1M@68525|delta/epsilon subdivisions,2YNZ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, iron-sulfur protein	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_1649418_1	1121438.JNJA01000025_gene2678	3.35e-29	115.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2M8CF@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_1028247_2	1123228.AUIH01000007_gene2618	3.54e-83	254.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XI6G@135619|Oceanospirillales	135619|Oceanospirillales	C	Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_293640_1	90814.KL370891_gene104	8.32e-264	734.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales	72273|Thiotrichales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_293640_2	90814.KL370891_gene105	3.5e-11	61.2	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_576123_1	411154.GFO_2692	6.18e-18	80.5	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1HZU1@117743|Flavobacteriia	976|Bacteroidetes	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
k59_576123_2	1121931.AUHG01000011_gene1830	6.76e-70	213.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8H@976|Bacteroidetes,1I307@117743|Flavobacteriia	976|Bacteroidetes	S	Orotate phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_576123_3	411154.GFO_2690	2.23e-143	405.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
k59_576123_4	411154.GFO_2689	1.24e-97	287.0	COG0494@1|root,COG0494@2|Bacteria,4PKI3@976|Bacteroidetes,1IJ9T@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_349464_1	1121931.AUHG01000015_gene1306	4.19e-213	590.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_406758_1	411154.GFO_3364	7.54e-108	314.0	COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,1HWUU@117743|Flavobacteriia	976|Bacteroidetes	O	proline hydroxylase	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
k59_350616_2	1484460.JSWG01000012_gene1544	1.8e-130	374.0	COG0745@1|root,COG0745@2|Bacteria,4NGNK@976|Bacteroidetes,1HYF6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_350616_3	1380600.AUYN01000009_gene1181	1.01e-99	304.0	COG0642@1|root,COG2205@2|Bacteria,4NISE@976|Bacteroidetes,1I00Q@117743|Flavobacteriia	976|Bacteroidetes	T	Signal Transduction Histidine Kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_238886_1	90814.KL370891_gene1019	6.25e-114	345.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,45ZPV@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_238886_2	90814.KL370891_gene1020	2.96e-54	173.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,460R8@72273|Thiotrichales	72273|Thiotrichales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_1084663_1	1121931.AUHG01000011_gene1762	3.96e-14	71.6	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
k59_1084663_2	411154.GFO_2761	1.37e-106	309.0	COG0668@1|root,COG0668@2|Bacteria,4NP36@976|Bacteroidetes,1I1XC@117743|Flavobacteriia	976|Bacteroidetes	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1424176_1	1121931.AUHG01000018_gene1365	1.1e-152	437.0	COG0460@1|root,COG0460@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
k59_11904_1	318161.Sden_2649	7.21e-10	61.6	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1S0D6@1236|Gammaproteobacteria,2QCD8@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Glycosyl transferase 4-like	wbbO	-	-	ko:K13004,ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
k59_11904_2	944546.ABED_0637	1.22e-21	92.8	COG0451@1|root,COG0451@2|Bacteria,1Q1MW@1224|Proteobacteria,42QQU@68525|delta/epsilon subdivisions,2YP2V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_1707161_1	317025.Tcr_1838	6.26e-27	103.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,4615R@72273|Thiotrichales	72273|Thiotrichales	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_1707161_2	90814.KL370891_gene1797	4.1e-220	611.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,45ZWM@72273|Thiotrichales	72273|Thiotrichales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_1707161_3	90814.KL370891_gene1798	2.64e-37	130.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,460IK@72273|Thiotrichales	72273|Thiotrichales	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
k59_1481073_1	929558.SMGD1_2209	6.65e-102	316.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran
k59_1707162_1	1123518.ARWI01000001_gene2173	1.66e-23	98.2	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_1707162_2	1123518.ARWI01000001_gene2174	3.61e-63	196.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C
k59_1707162_3	1123518.ARWI01000001_gene2175	2.18e-145	419.0	COG1271@1|root,COG1271@2|Bacteria,1R5SQ@1224|Proteobacteria,1RY58@1236|Gammaproteobacteria,461TF@72273|Thiotrichales	72273|Thiotrichales	C	oxidase subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_577455_1	573370.DMR_35190	0.000161	49.3	COG2208@1|root,COG3287@1|root,COG2208@2|Bacteria,COG3287@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2M95A@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FIST,FIST_C,PAS_3,SpoIIE
k59_577455_2	1123514.KB905900_gene2227	2.01e-66	214.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462B1@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k59_182421_1	929558.SMGD1_1476	6.5e-45	164.0	COG1413@1|root,COG1413@2|Bacteria,1QZXI@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182421_2	1357400.HMPREF2086_01849	2.9e-20	92.4	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1312313_1	1443665.JACA01000001_gene2613	2.55e-24	100.0	COG0589@1|root,COG0589@2|Bacteria,4NE48@976|Bacteroidetes,1HXRC@117743|Flavobacteriia,2YHS0@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1437683_1	1046627.BZARG_1373	1.42e-79	246.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_981436_1	637905.SVI_0075	9.47e-15	70.5	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,2QAN9@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840	-	-	-	-	-	-	-	-	-	-	Hexapep
k59_1205133_1	1123401.JHYQ01000018_gene2402	6.98e-19	85.9	COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,460TW@72273|Thiotrichales	72273|Thiotrichales	S	High frequency lysogenization protein hflD homolog	hflD	-	-	ko:K07153	-	-	-	-	ko00000	-	-	-	DUF489
k59_1205133_2	338963.Pcar_0451	9.09e-24	97.1	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,43UX2@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaC protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_929316_1	1123514.KB905899_gene1782	2.31e-07	50.8	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,4611K@72273|Thiotrichales	72273|Thiotrichales	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_929316_2	317025.Tcr_1416	2.74e-77	240.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales	72273|Thiotrichales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1155001_2	1121931.AUHG01000020_gene3133	1.82e-74	228.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_818305_1	1122225.AULQ01000002_gene493	3.12e-87	266.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1HY7T@117743|Flavobacteriia	976|Bacteroidetes	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1437698_1	93059.P9211_07651	5.57e-27	111.0	COG0438@1|root,COG0438@2|Bacteria,1GIW5@1117|Cyanobacteria,1MN65@1212|Prochloraceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1043119_1	1347342.BN863_3200	7.46e-196	553.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1HWNF@117743|Flavobacteriia	976|Bacteroidetes	E	NADPH-dependent glutamate synthase beta chain and related	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1043119_2	688270.Celal_0768	5.71e-63	215.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia,1F8E9@104264|Cellulophaga	976|Bacteroidetes	C	COGs COG0069 Glutamate synthase domain 2	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1437712_1	323850.Shew_1348	9.15e-142	412.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,2QA5Y@267890|Shewanellaceae	1236|Gammaproteobacteria	N	PFAM flagellar basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_1495623_1	411154.GFO_1621	4.72e-313	865.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HX9T@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_706251_1	1121918.ARWE01000001_gene2054	6.7e-150	431.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,43TMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1550435_1	411154.GFO_2538	1.4e-39	139.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_1550435_2	411154.GFO_2537	8.44e-69	211.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_253475_1	1397527.Q670_02285	8.76e-35	131.0	COG2207@1|root,COG2207@2|Bacteria,1R5D8@1224|Proteobacteria,1RYEI@1236|Gammaproteobacteria,1XMYF@135619|Oceanospirillales	135619|Oceanospirillales	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_1721300_1	1239415.CM001837_gene2009	2.72e-25	102.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1HWNU@117743|Flavobacteriia,37DMM@326319|Dokdonia	976|Bacteroidetes	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1721300_2	411154.GFO_1450	1.32e-63	208.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_818348_1	323850.Shew_0339	1.02e-111	332.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2QB9P@267890|Shewanellaceae	1236|Gammaproteobacteria	J	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,RhlB
k59_1437737_1	929558.SMGD1_2066	3.47e-121	364.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2YN2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_981495_1	572480.Arnit_0370	2.91e-103	311.0	COG3487@1|root,COG3487@2|Bacteria,1MX5H@1224|Proteobacteria,42ZHF@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Imelysin	icmP	-	-	ko:K07231	-	-	-	-	ko00000	-	-	-	Peptidase_M75
k59_1550451_1	572480.Arnit_0710	6.6e-21	87.4	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_1550451_2	572480.Arnit_0709	8.01e-72	236.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_309134_1	1123518.ARWI01000001_gene2080	2.06e-152	453.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,45ZUZ@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_309134_2	1026882.MAMP_03125	9.57e-16	75.1	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,4616B@72273|Thiotrichales	72273|Thiotrichales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_1098565_1	317025.Tcr_1118	3.83e-74	237.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,45ZPK@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_706301_1	1123518.ARWI01000001_gene260	7.67e-94	281.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,46015@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_591017_1	985255.APHJ01000043_gene436	2.78e-49	162.0	COG0526@1|root,COG0526@2|Bacteria,4NQ50@976|Bacteroidetes,1I2VW@117743|Flavobacteriia,2P7MJ@244698|Gillisia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k59_196601_1	984262.SGRA_1960	2.82e-52	181.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_309147_1	1121931.AUHG01000010_gene560	7.67e-96	286.0	COG4768@1|root,COG4768@2|Bacteria,4NIFH@976|Bacteroidetes,1I01R@117743|Flavobacteriia	976|Bacteroidetes	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_253524_1	1120948.KB903218_gene2086	4.09e-83	270.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DXNT@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1268760_1	247634.GPB2148_1599	1.08e-08	62.0	COG3950@1|root,COG4938@1|root,COG3950@2|Bacteria,COG4938@2|Bacteria,1NEEG@1224|Proteobacteria,1RZWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
k59_760039_1	1336803.PHEL49_0962	0.000188	47.8	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NEPS@976|Bacteroidetes,1HYQ1@117743|Flavobacteriia,3VWRE@52959|Polaribacter	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_7,TPR_8
k59_1098585_1	929558.SMGD1_1029	7.6e-147	421.0	COG2951@1|root,COG2951@2|Bacteria,1PPIK@1224|Proteobacteria,43ABD@68525|delta/epsilon subdivisions,2YQXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_1609572_1	1121012.AUKX01000011_gene2325	1.19e-17	81.6	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia,23GIY@178469|Arenibacter	976|Bacteroidetes	L	Helicase and RNase D C-terminal	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_1609572_2	391603.FBALC1_05898	6.96e-195	543.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_1495696_1	592029.DDD_0943	3.57e-93	282.0	COG2972@1|root,COG2972@2|Bacteria,4NIER@976|Bacteroidetes,1IIPA@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
k59_534870_1	1458427.BAWN01000011_gene687	4.8e-29	122.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,4ABVX@80864|Comamonadaceae	28216|Betaproteobacteria	P	von Willebrand factor, type A	cbbO	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
k59_1778583_1	216432.CA2559_02930	2.84e-169	491.0	28NP5@1|root,2ZBP5@2|Bacteria,4NFTH@976|Bacteroidetes,1HYRG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	O-ag_pol_Wzy
k59_1778583_2	906888.JCM19314_2705	1.07e-58	204.0	COG3307@1|root,COG3307@2|Bacteria,4NUP9@976|Bacteroidetes,1IF9G@117743|Flavobacteriia,3HKIR@363408|Nonlabens	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_1778583_3	1046724.KB889919_gene146	1.76e-08	63.9	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	capM2_2	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1778583_4	216432.CA2559_02945	3.28e-96	283.0	COG0110@1|root,COG0110@2|Bacteria,4NMZ2@976|Bacteroidetes,1I1H0@117743|Flavobacteriia	976|Bacteroidetes	S	acetyltransferase, isoleucine patch superfamily	wcaF	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
k59_1778583_5	1336803.PHEL49_0215	3.38e-122	363.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_1778583_6	59374.Fisuc_0995	1.64e-84	265.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	gne	-	5.1.3.2,5.1.3.26	ko:K01784,ko:K19997	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_1155114_1	929558.SMGD1_0384	4.59e-15	73.9	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YNWH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_1155114_2	443144.GM21_0757	1.6e-06	56.2	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria,43V4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	cheW40H-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_1327063_1	990073.ATHU01000001_gene1061	3.31e-71	219.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2YN7T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transferase	pglC	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
k59_1327063_2	1121012.AUKX01000058_gene1359	7.2e-12	66.2	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,1HXBG@117743|Flavobacteriia,23HNC@178469|Arenibacter	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_1437807_1	563040.Saut_1819	1.76e-61	195.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2YM7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0510	DapB_C,DapB_N
k59_875699_1	1347342.BN863_4290	7.4e-83	248.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1I1XM@117743|Flavobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_875699_2	1380600.AUYN01000009_gene1357	2.09e-63	203.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,1HZ4X@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1329154_1	977880.RALTA_A1035	3.46e-78	234.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,1K10B@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_1329154_2	1123518.ARWI01000001_gene2255	4.04e-12	64.7	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,460NB@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_85598_1	563040.Saut_1723	2.08e-70	231.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42REV@68525|delta/epsilon subdivisions,2YR6S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF,HD
k59_536903_1	1232410.KI421421_gene3683	3.69e-102	305.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,43U6N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
k59_1611740_1	1499499.EV06_0346	7.93e-10	59.3	COG1028@1|root,COG1028@2|Bacteria,1G0MD@1117|Cyanobacteria,1MKQB@1212|Prochloraceae	1117|Cyanobacteria	IQ	Alternative locus ID	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1611740_2	443144.GM21_1157	2.53e-36	124.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,43SPX@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_424058_1	1469557.JSWF01000014_gene2652	9.41e-105	326.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_1270859_1	945713.IALB_0011	2.82e-78	236.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_875726_1	563040.Saut_0140	5.77e-77	241.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2YMEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
k59_1497863_1	869213.JCM21142_104099	9.3e-54	188.0	COG1629@1|root,COG1629@2|Bacteria,4PM72@976|Bacteroidetes,47Y3N@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4139,DUF4140,Plug
k59_593062_1	1237149.C900_01655	3.35e-39	152.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG0642@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
k59_708707_1	1123517.JOMR01000001_gene1533	1.57e-90	274.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,462SM@72273|Thiotrichales	72273|Thiotrichales	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
k59_708707_2	90814.KL370891_gene548	1.36e-61	195.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_762152_1	572480.Arnit_2533	2.59e-115	349.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42PU8@68525|delta/epsilon subdivisions	1224|Proteobacteria	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
k59_1100711_1	1178825.ALIH01000011_gene84	2.29e-162	479.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1157282_1	929558.SMGD1_0707	5.65e-18	85.1	COG2911@1|root,COG2911@2|Bacteria,1NRGB@1224|Proteobacteria,42MD0@68525|delta/epsilon subdivisions,2YMIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27344_1	1565129.JSFF01000012_gene554	1.76e-117	342.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,2QAEN@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM YicC N-terminal domain protein	yicC	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_1611784_2	443152.MDG893_11336	3.5e-77	233.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,468IV@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
k59_1611784_3	1123518.ARWI01000001_gene1780	2.34e-125	359.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	UPF0056 membrane protein	ychE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_1497902_1	1565129.JSFF01000005_gene2318	1.88e-93	287.0	COG1639@1|root,COG2203@1|root,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria,2QB1K@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HDOD,Pkinase
k59_311290_1	929558.SMGD1_1877	4.28e-81	258.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2YMKP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_931482_1	572480.Arnit_1919	1.19e-91	293.0	COG2982@1|root,COG3164@1|root,COG2982@2|Bacteria,COG3164@2|Bacteria,1QA6E@1224|Proteobacteria,42NCN@68525|delta/epsilon subdivisions,2YM89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_1,DUF3971
k59_481223_1	504487.JCM19302_2597	1.85e-307	839.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia	976|Bacteroidetes	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_481223_2	504487.JCM19302_2596	3.06e-70	216.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1I1AS@117743|Flavobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_481223_3	1137281.D778_01781	4.58e-148	423.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1HX72@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_820603_1	709032.Sulku_1324	6.78e-81	246.0	COG2199@1|root,COG3706@2|Bacteria,1NY4T@1224|Proteobacteria,42YUI@68525|delta/epsilon subdivisions,2YR50@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1157305_1	1353528.DT23_04845	2.46e-134	385.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,2XN0M@285107|Thioclava	28211|Alphaproteobacteria	J	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_85686_1	1004149.AFOE01000016_gene1592	3.57e-28	111.0	COG0363@1|root,COG0363@2|Bacteria,4NGB9@976|Bacteroidetes,1HY6P@117743|Flavobacteriia	976|Bacteroidetes	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_650327_1	563040.Saut_1927	1.96e-112	333.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_650327_2	326298.Suden_1919	4.83e-13	68.2	COG2857@1|root,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_593126_1	865937.Gilli_2887	7.64e-19	84.7	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia,2P5VC@244698|Gillisia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_593126_2	926562.Oweho_1753	1.02e-85	261.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PAAG@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_1329252_1	1123355.JHYO01000004_gene2464	2.38e-98	303.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2U2AJ@28211|Alphaproteobacteria,36YJZ@31993|Methylocystaceae	28211|Alphaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_1329252_2	1123514.KB905901_gene10	1.65e-117	347.0	2EXA2@1|root,33QKS@2|Bacteria,1NS4W@1224|Proteobacteria,1SN3N@1236|Gammaproteobacteria,46201@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_820634_1	90814.KL370892_gene2314	6.76e-144	433.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535,ko:K12955	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.24,3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_536995_1	1121931.AUHG01000012_gene2701	8.65e-68	226.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1100772_1	32024.JMTI01000018_gene461	4.6e-06	49.7	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	cprR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1100772_2	572480.Arnit_1607	5.78e-53	174.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,42PPJ@68525|delta/epsilon subdivisions,2YN31@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_875808_1	1116375.VEJY3_22691	1.48e-35	124.0	COG2963@1|root,COG2963@2|Bacteria,1N04F@1224|Proteobacteria,1S6GJ@1236|Gammaproteobacteria,1Y27B@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_140900_1	504487.JCM19302_508	3.54e-167	472.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1HYDI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_27399_1	945713.IALB_3110	1.87e-75	234.0	COG5587@1|root,COG5587@2|Bacteria	2|Bacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
k59_366652_1	1476902.A0A067ZG37_9CAUD	1.39e-45	162.0	4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPUI@28883|Caudovirales,4QIGP@10662|Myoviridae	10662|Myoviridae	S	Clp protease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_366652_2	1157490.EL26_01770	8.88e-24	95.5	2E4UU@1|root,32ZP7@2|Bacteria,1VEZP@1239|Firmicutes,4HQGN@91061|Bacilli	91061|Bacilli	S	Bacteriophage lambda head decoration protein D	-	-	-	-	-	-	-	-	-	-	-	-	HDPD
k59_893188_1	90814.KL370891_gene255	1.74e-35	122.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,460PX@72273|Thiotrichales	72273|Thiotrichales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_893188_2	90814.KL370891_gene254	3.06e-79	247.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1289187_1	94122.Shewana3_2560	4.45e-59	190.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,2Q96S@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360	ACP_syn_III,ACP_syn_III_C
k59_1289187_2	323850.Shew_1602	3.92e-28	108.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,2Q8G6@267890|Shewanellaceae	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
k59_1799134_1	929558.SMGD1_2567	2.29e-97	302.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2YNEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	2-acylglycerophosphoethanolamine acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_836937_1	929558.SMGD1_0536	2.58e-56	191.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2YTC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
k59_609239_1	1380600.AUYN01000006_gene701	5.7e-90	281.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,1HZ2A@117743|Flavobacteriia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_499142_1	1121931.AUHG01000010_gene711	1.92e-92	282.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_1175976_1	1250005.PHEL85_0101	5.81e-106	339.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia,3VW2R@52959|Polaribacter	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k59_384804_2	1484460.JSWG01000007_gene3076	1.84e-54	177.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
k59_1685485_1	929558.SMGD1_2850	3.84e-177	501.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2YNI5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_669176_1	1537917.JU82_01040	1.59e-15	74.3	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_669176_2	1449976.KALB_3493	0.000236	48.5	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,4EAGE@85010|Pseudonocardiales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k59_44436_2	1121459.AQXE01000006_gene139	3.96e-19	88.2	COG0679@1|root,COG0679@2|Bacteria,1RA01@1224|Proteobacteria,43AZE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_1457385_1	1137281.D778_01109	2.16e-110	323.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1HX58@117743|Flavobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_1799237_1	760154.Sulba_1898	6.3e-96	293.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2YN3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Alginate O-acetylation protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_1119466_1	435591.BDI_0204	5.65e-24	100.0	COG0212@1|root,COG0212@2|Bacteria,4NQRG@976|Bacteroidetes,2FQQB@200643|Bacteroidia,22Y6E@171551|Porphyromonadaceae	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_669224_1	749927.AMED_4263	4.96e-07	54.7	COG0859@1|root,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria,4DYGA@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
k59_669224_2	572480.Arnit_2238	2.6e-50	167.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2YMNJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_727800_1	1197477.IA57_01060	0.0	1050.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1516783_1	398579.Spea_3529	3.27e-87	265.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,2Q99J@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_948705_1	1123514.KB905903_gene384	3.93e-19	82.4	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,461E6@72273|Thiotrichales	72273|Thiotrichales	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_948705_2	1123518.ARWI01000001_gene1789	5.85e-22	92.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,1SCVK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_671406_1	1123257.AUFV01000008_gene561	2.34e-25	102.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1X6HJ@135614|Xanthomonadales	135614|Xanthomonadales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_1744607_1	497321.C664_17637	2.18e-75	228.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria,2KWET@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1744607_2	497321.C664_17632	2.46e-10	59.3	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,2KUF5@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_730009_1	318167.Sfri_1853	3.82e-15	74.3	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,2Q8KI@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	ykgF	-	-	ko:K18929	-	-	-	-	ko00000	-	-	iSF_1195.SF0259,iSFxv_1172.SFxv_0274,iS_1188.S0280	DUF3390,Fer4_8,LUD_dom
k59_730009_2	225849.swp_3635	1.75e-88	265.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RMVZ@1236|Gammaproteobacteria,2Q9US@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Cysteine-rich domain	ykgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K18928	-	-	-	-	ko00000	-	-	iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338	CCG
k59_219308_1	563040.Saut_1399	8.78e-67	207.0	COG1286@1|root,COG1286@2|Bacteria,1NIBK@1224|Proteobacteria,42U0P@68525|delta/epsilon subdivisions,2YPS8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_219308_2	929558.SMGD1_2395	1.25e-44	153.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,43D3D@68525|delta/epsilon subdivisions,2YTG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_46476_1	927677.ALVU02000002_gene163	1.84e-10	62.8	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H4ME@1142|Synechocystis	1117|Cyanobacteria	T	Phytochrome region	cph2	GO:0003674,GO:0006464,GO:0006807,GO:0007154,GO:0007165,GO:0007602,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009585,GO:0009605,GO:0009628,GO:0009639,GO:0009881,GO:0009883,GO:0009987,GO:0010017,GO:0018298,GO:0019538,GO:0023052,GO:0036211,GO:0038023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0060089,GO:0065007,GO:0071214,GO:0071478,GO:0071482,GO:0071489,GO:0071704,GO:0104004,GO:1901564	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PHY
k59_219322_2	377629.TERTU_0887	4.75e-87	258.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,2PNDV@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Ribosomal protein S7p/S5e	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_332225_1	1172190.M947_02080	2.06e-23	91.3	COG2863@1|root,COG2863@2|Bacteria,1Q9CC@1224|Proteobacteria,43118@68525|delta/epsilon subdivisions,2YS5W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1402675_1	1355368.JART01000014_gene566	8.15e-49	176.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_1064094_1	1123517.JOMR01000001_gene1207	2.36e-66	219.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_332254_1	1123037.AUDE01000011_gene928	1.68e-37	138.0	COG4974@1|root,COG4974@2|Bacteria,4NX3Q@976|Bacteroidetes,1HYQ2@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
k59_1459487_1	1121931.AUHG01000011_gene2234	6.1e-63	198.0	COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,1HX4N@117743|Flavobacteriia	976|Bacteroidetes	S	beta-phosphoglucomutase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_1459487_2	411154.GFO_2134	1.43e-20	89.7	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_1744701_1	929558.SMGD1_2856	4.91e-72	225.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2YPWY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_1628482_1	411154.GFO_0138	2.93e-213	612.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_1224025_1	1249997.JHZW01000003_gene3772	4.07e-106	328.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,1INAV@117743|Flavobacteriia,2PI0U@252356|Maribacter	976|Bacteroidetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_1121850_2	1168067.JAGP01000001_gene926	1.24e-52	172.0	COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,46163@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein conserved in bacteria (DUF2058)	-	-	-	ko:K09912	-	-	-	-	ko00000	-	-	-	DUF2058
k59_1519189_1	411154.GFO_1447	8e-27	103.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
k59_1519189_2	1121931.AUHG01000012_gene2717	2.09e-110	328.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1HWNU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1224033_1	572480.Arnit_2845	3.73e-107	311.0	2AIWB@1|root,319DT@2|Bacteria,1Q2F3@1224|Proteobacteria,42VJD@68525|delta/epsilon subdivisions,2YQCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1224033_2	572480.Arnit_2844	2.64e-24	100.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2YMTZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_501530_1	1123514.KB905902_gene284	4.89e-88	271.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,1SM3A@1236|Gammaproteobacteria,462WD@72273|Thiotrichales	72273|Thiotrichales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_106737_1	945713.IALB_2703	1.63e-61	204.0	COG3303@1|root,COG4412@1|root,COG3303@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,DUF4859,Paired_CXXCH_1
k59_1121880_1	376686.Fjoh_2912	2.38e-33	120.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia,2P070@237|Flavobacterium	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1121880_2	1122225.AULQ01000001_gene1865	6.13e-26	105.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1HYKQ@117743|Flavobacteriia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k59_1350501_1	929558.SMGD1_1306	8.38e-54	189.0	COG2199@1|root,COG2199@2|Bacteria,1MUQV@1224|Proteobacteria,43BUD@68525|delta/epsilon subdivisions,2YTD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_1744758_1	1249975.JQLP01000005_gene790	2.73e-41	148.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1HXCK@117743|Flavobacteriia,2P5X8@244698|Gillisia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_1744758_2	411154.GFO_0243	9.36e-69	213.0	2BVTQ@1|root,2Z7J9@2|Bacteria,4NGSY@976|Bacteroidetes,1HWRX@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k59_611423_1	316067.Geob_3515	3.96e-25	105.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria	1224|Proteobacteria	E	Extracellular liganD-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	DctP,Peripla_BP_6
k59_1459548_1	1178825.ALIH01000001_gene2586	3.07e-105	323.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1HZII@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
k59_1744762_1	1165841.SULAR_08839	1.23e-30	111.0	COG0735@1|root,COG0735@2|Bacteria,1NCW6@1224|Proteobacteria,42VHY@68525|delta/epsilon subdivisions,2YQK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_1744762_2	944547.ABLL_2210	1.76e-14	73.2	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YM8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_106769_1	323850.Shew_0713	3.52e-25	103.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RSJR@1236|Gammaproteobacteria,2Q9IU@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_106769_2	323850.Shew_0712	1.21e-65	209.0	COG1120@1|root,COG1120@2|Bacteria,1MWPV@1224|Proteobacteria,1T1UT@1236|Gammaproteobacteria,2Q9WP@267890|Shewanellaceae	1236|Gammaproteobacteria	P	SMART AAA ATPase	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_106773_1	1232410.KI421414_gene2909	1.38e-88	266.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,42RHH@68525|delta/epsilon subdivisions,2WNVX@28221|Deltaproteobacteria,43TK9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	LrgB-like family	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
k59_1459578_1	391603.FBALC1_05913	3.47e-14	71.6	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein related to penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k59_1459578_2	1046627.BZARG_1709	1.81e-52	168.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_274172_1	945713.IALB_0589	1.45e-47	160.0	COG0462@1|root,COG0462@2|Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Pribosyl_synth,Pribosyltran_N
k59_838638_1	929558.SMGD1_2771	3.64e-64	215.0	COG5001@1|root,COG5001@2|Bacteria,1R4H0@1224|Proteobacteria,43CII@68525|delta/epsilon subdivisions,2YTD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_555869_1	911239.CF149_00962	3.05e-75	236.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RMII@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_1402825_1	411154.GFO_3429	1.66e-29	112.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_1402825_2	1121931.AUHG01000010_gene412	2.04e-44	150.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,LVIVD
k59_1459602_1	929558.SMGD1_0391	9.16e-90	283.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2YMVN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_501606_1	745718.JADT01000001_gene2061	2.64e-210	588.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k59_46647_1	317025.Tcr_1851	3.25e-32	125.0	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,463M4@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_46647_2	1150621.SMUL_0717	6.29e-73	223.0	COG0748@1|root,COG0748@2|Bacteria,1MY8K@1224|Proteobacteria,42NQN@68525|delta/epsilon subdivisions,2YM8E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Heme iron utilization protein	chuZ	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx
k59_1350568_1	666686.B1NLA3E_20720	9.12e-20	97.1	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_1459607_1	1565129.JSFF01000001_gene1146	1.09e-54	171.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,2QCAP@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1291678_1	1172190.M947_10415	3.22e-70	235.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2YMIZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_106824_1	667632.KB890164_gene1743	7.54e-21	95.5	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria,1K1X2@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM secretion protein HlyD family protein	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
k59_611510_1	717772.THIAE_04210	1.56e-26	101.0	COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,463BK@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
k59_611513_1	411154.GFO_3377	2.25e-88	262.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_1004611_1	1178825.ALIH01000010_gene370	8.58e-48	172.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HX6K@117743|Flavobacteriia	976|Bacteroidetes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
k59_160848_1	945713.IALB_1843	3.96e-74	229.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_1004615_1	411154.GFO_2931	2.75e-156	446.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_274225_1	929558.SMGD1_1516	3.93e-75	233.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_274225_2	1172190.M947_05945	7.41e-26	97.8	2AIVC@1|root,32MS0@2|Bacteria,1Q3D2@1224|Proteobacteria,42X4G@68525|delta/epsilon subdivisions,2YQTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF4006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4006
k59_1122008_1	1165841.SULAR_04502	1.58e-58	196.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2YNNY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_795848_1	317025.Tcr_1654	9.17e-108	337.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,45ZMV@72273|Thiotrichales	72273|Thiotrichales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_2,OstA_C
k59_569676_2	572480.Arnit_0516	1.89e-124	376.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,42M8I@68525|delta/epsilon subdivisions,2YN4J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_174623_1	391587.KAOT1_17228	3.27e-96	294.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1756167_1	323850.Shew_0947	4.03e-95	292.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,1RQM5@1236|Gammaproteobacteria,2QAPI@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	mcar-1	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
k59_1190080_1	367737.Abu_2145	1.11e-26	104.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2YP2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	nssR	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_1190080_2	326298.Suden_1838	7.15e-32	117.0	COG5592@1|root,COG5592@2|Bacteria,1QVT0@1224|Proteobacteria,42UVT@68525|delta/epsilon subdivisions,2YPZH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_739247_1	269799.Gmet_2710	1.38e-69	234.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_1529739_1	1131812.JQMS01000001_gene255	9.95e-82	249.0	COG1216@1|root,COG1216@2|Bacteria,4NJMY@976|Bacteroidetes,1HYJN@117743|Flavobacteriia,2NZ6I@237|Flavobacterium	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1361281_2	1250006.JHZZ01000001_gene2229	1.45e-71	229.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1248488_1	563040.Saut_0318	1.17e-117	371.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1644698_1	1288826.MSNKSG1_05291	4.7e-68	213.0	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,467KI@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Anti-ECFsigma factor ChrR	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
k59_458629_1	1229487.AMYW01000005_gene235	6.87e-25	108.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1HXWR@117743|Flavobacteriia,2NSCU@237|Flavobacterium	976|Bacteroidetes	G	Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k59_740574_1	1131553.JIBI01000087_gene2419	1.74e-99	296.0	COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,2VN85@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_514380_1	1121875.KB907555_gene403	2.25e-68	216.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1HXAV@117743|Flavobacteriia	976|Bacteroidetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k59_1248499_1	317025.Tcr_0069	2.15e-22	96.3	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,463UP@72273|Thiotrichales	72273|Thiotrichales	I	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1248499_2	1123514.KB905902_gene240	7.81e-67	213.0	COG1416@1|root,COG1416@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE,zf-HC2
k59_1248499_3	1123514.KB905902_gene241	2.28e-81	246.0	COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1248499_4	1123518.ARWI01000001_gene1407	3.21e-61	192.0	COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,4633S@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_458647_1	616991.JPOO01000001_gene3942	4.41e-51	166.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1I1AR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_458647_3	1197477.IA57_10260	1.59e-56	181.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,1I2B8@117743|Flavobacteriia	976|Bacteroidetes	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
k59_458647_4	1249975.JQLP01000005_gene2489	2.79e-16	73.9	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia,2P6H4@244698|Gillisia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_344823_1	411154.GFO_1950	5.57e-65	218.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,1HZCQ@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_344823_2	411154.GFO_1949	8.1e-40	137.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1HY18@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_288903_1	1121931.AUHG01000016_gene989	1.52e-77	239.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1248525_1	1380600.AUYN01000009_gene1782	8.88e-210	590.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
k59_1306139_1	411154.GFO_2232	7.87e-100	305.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
k59_288944_1	1172190.M947_10640	3.13e-12	64.3	COG2932@1|root,COG2932@2|Bacteria,1RIP6@1224|Proteobacteria,42RJG@68525|delta/epsilon subdivisions,2YP8P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	phage repressor	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24,Phage_CI_repr
k59_288944_2	827.JFJK01000021_gene106	2.32e-08	59.3	COG0791@1|root,COG0791@2|Bacteria,1R66V@1224|Proteobacteria,43ACC@68525|delta/epsilon subdivisions,2YT0M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	SH3 domain of SH3b2 type	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_1588425_1	1249975.JQLP01000003_gene235	2.6e-119	358.0	COG0531@1|root,COG0531@2|Bacteria,4NHS2@976|Bacteroidetes,1HX4J@117743|Flavobacteriia,2P78A@244698|Gillisia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_797496_1	709032.Sulku_1262	5.73e-12	69.7	COG5126@1|root,COG5126@2|Bacteria,1RKQX@1224|Proteobacteria,42WWA@68525|delta/epsilon subdivisions	1224|Proteobacteria	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5,EF-hand_7,EF-hand_8
k59_1588431_1	1168067.JAGP01000001_gene1581	7.7e-135	387.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,4606W@72273|Thiotrichales	72273|Thiotrichales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_1588431_2	90814.KL370891_gene1647	5.2e-57	179.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,46147@72273|Thiotrichales	72273|Thiotrichales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_63137_1	1178825.ALIH01000008_gene768	4.65e-16	74.3	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1HYFU@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_63137_2	1178825.ALIH01000008_gene767	1.94e-56	192.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,1I2VC@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8
k59_6251_1	323850.Shew_2349	1.73e-112	335.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,2Q8WQ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	phoQ	-	2.7.13.3	ko:K07637	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,PhoQ_Sensor
k59_853215_1	1442598.JABW01000003_gene101	2.74e-19	85.1	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2YNDN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_853215_2	563040.Saut_0259	5.66e-149	426.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2YNH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_853215_3	1385420.FRA_34c06300	4.8e-07	49.7	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,460IX@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_1474828_1	1237149.C900_01790	2.69e-06	51.2	COG0729@1|root,COG2911@1|root,COG0729@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Haemagg_act,Peptidase_S74
k59_1701145_1	1123366.TH3_08304	1.92e-52	171.0	COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,2TV1A@28211|Alphaproteobacteria,2JUNT@204441|Rhodospirillales	204441|Rhodospirillales	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
k59_966757_1	1484460.JSWG01000006_gene2931	5.59e-206	590.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1I0HE@117743|Flavobacteriia	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_628013_1	572480.Arnit_2777	1.54e-93	291.0	COG0642@1|root,COG3287@1|root,COG0642@2|Bacteria,COG3287@2|Bacteria,1NXDJ@1224|Proteobacteria,43CBD@68525|delta/epsilon subdivisions,2YQE7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA
k59_458749_1	497321.C664_11330	7.34e-108	315.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,2KUNS@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_740671_1	1347342.BN863_6110	8.14e-32	121.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,1HZQ1@117743|Flavobacteriia	976|Bacteroidetes	HJ	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
k59_740671_2	655815.ZPR_1992	3.05e-175	512.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1HYK9@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
k59_6273_1	572480.Arnit_1178	5.56e-43	147.0	COG0451@1|root,COG0451@2|Bacteria,1QY1S@1224|Proteobacteria,42X11@68525|delta/epsilon subdivisions,2YS6I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6273_2	572480.Arnit_1174	3.21e-39	132.0	COG2350@1|root,COG2350@2|Bacteria,1N8AZ@1224|Proteobacteria,42V5N@68525|delta/epsilon subdivisions,2YQFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_402100_1	929558.SMGD1_1247	3.88e-112	333.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_684825_1	929558.SMGD1_0008	3.42e-53	186.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_684825_2	257310.BB0912	2.19e-12	71.2	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2VGZB@28216|Betaproteobacteria,3T2GT@506|Alcaligenaceae	28216|Betaproteobacteria	L	DNA methylase	mod	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_910131_1	1123518.ARWI01000001_gene2228	7.47e-44	152.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1RRM3@1236|Gammaproteobacteria,461HM@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K11707	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_571404_1	1137281.D778_02788	7e-78	243.0	28IUS@1|root,2Z8TF@2|Bacteria,4NIVZ@976|Bacteroidetes,1HXSQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_402127_1	1408473.JHXO01000013_gene608	1.71e-82	272.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_684852_1	1115515.EV102420_46_00003	2.17e-06	47.8	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,1S8U2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_458799_2	1123518.ARWI01000001_gene685	5.47e-145	418.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,45ZP1@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_1531261_1	376686.Fjoh_3909	5.89e-50	166.0	COG0680@1|root,COG0680@2|Bacteria,4NRQY@976|Bacteroidetes,1INAP@117743|Flavobacteriia,2NYUY@237|Flavobacterium	976|Bacteroidetes	E	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_1588523_2	999419.HMPREF1077_02043	4.85e-21	97.1	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_1418642_1	929558.SMGD1_1864	1.51e-32	124.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2YP6V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_1023581_1	945713.IALB_2286	1.68e-17	85.5	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_119439_1	572480.Arnit_0695	7.24e-61	188.0	COG0718@1|root,COG0718@2|Bacteria,1Q3T8@1224|Proteobacteria,42UGW@68525|delta/epsilon subdivisions,2YPUE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_119439_2	572480.Arnit_0696	1.06e-80	246.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2YMV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_458806_1	641526.ADIWIN_3168	9.58e-96	301.0	COG4772@1|root,COG4772@2|Bacteria,4NEUH@976|Bacteroidetes,1HXXK@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_514544_1	1000565.METUNv1_02254	1.02e-53	175.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2VQ7A@28216|Betaproteobacteria,2KW86@206389|Rhodocyclales	206389|Rhodocyclales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_289063_1	1380600.AUYN01000001_gene2230	4.69e-11	60.1	COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,1I1BH@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k59_289063_2	983544.Lacal_2442	5.45e-41	142.0	COG0101@1|root,COG0101@2|Bacteria,4NG3N@976|Bacteroidetes,1HX0T@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_1361449_1	1380600.AUYN01000006_gene428	3.24e-28	111.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1HY1T@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1418650_1	1236541.BALL01000043_gene3991	9.07e-19	79.7	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,1RP1B@1236|Gammaproteobacteria,2Q9S9@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM formate dehydrogenase, gamma subunit	fdoI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1418650_2	1236541.BALL01000043_gene3990	9.53e-54	172.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RRAN@1236|Gammaproteobacteria,2Q8I3@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	fdhB	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_1306275_1	111780.Sta7437_4112	2.99e-06	56.6	COG4932@1|root,COG4932@2|Bacteria,1GIGP@1117|Cyanobacteria,3VKF3@52604|Pleurocapsales	1117|Cyanobacteria	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
k59_1701232_1	317025.Tcr_0954	1.07e-113	337.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,460BD@72273|Thiotrichales	72273|Thiotrichales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1474923_1	1380600.AUYN01000007_gene3184	4.3e-65	202.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
k59_1474923_2	1197477.IA57_05625	3.32e-41	135.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_628095_1	983544.Lacal_0047	4.07e-134	384.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1135979_2	563040.Saut_1933	1.08e-50	165.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2YNYN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin synthase alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1079096_1	1237149.C900_03757	1.49e-75	226.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,47R7M@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
k59_402198_1	317025.Tcr_0965	4.06e-69	219.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,462MK@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_232914_2	1004149.AFOE01000010_gene2483	3.07e-55	179.0	2FJXI@1|root,34BJY@2|Bacteria,4P6PT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232914_4	504487.JCM19302_2367	2.25e-80	239.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_232914_5	1189620.AJXL01000033_gene2860	3.73e-43	150.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia,2NSBH@237|Flavobacterium	976|Bacteroidetes	EH	Aminotransferase class IV	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1306313_1	985255.APHJ01000024_gene1134	4.51e-87	270.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia,2P5EP@244698|Gillisia	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
k59_1248726_1	745718.JADT01000005_gene89	4.32e-25	104.0	COG0438@1|root,COG0438@2|Bacteria,4NE53@976|Bacteroidetes,1HX83@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_1248726_2	985255.APHJ01000028_gene976	8.4e-16	72.8	COG1045@1|root,COG1045@2|Bacteria,4NQ3J@976|Bacteroidetes,1I3M6@117743|Flavobacteriia	976|Bacteroidetes	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_1191115_1	944547.ABLL_0514	1.6e-36	140.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1NU9A@1224|Proteobacteria,42YSZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,dCache_2
k59_119490_1	1353537.TP2_11710	2.12e-113	344.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,2XN3W@285107|Thioclava	28211|Alphaproteobacteria	C	Catalyzes the transfer of electrons from NADH to quinone	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
k59_6379_1	929558.SMGD1_0564	2.23e-32	116.0	COG0607@1|root,COG0607@2|Bacteria,1R70B@1224|Proteobacteria,42UX5@68525|delta/epsilon subdivisions,2YPT0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_6379_2	1172190.M947_11650	4.29e-24	100.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNNQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1487620_1	1453505.JASY01000002_gene2258	1.01e-16	84.7	COG1196@1|root,COG3064@1|root,COG1196@2|Bacteria,COG3064@2|Bacteria,4NGJZ@976|Bacteroidetes,1HY5X@117743|Flavobacteriia,2NVFU@237|Flavobacterium	976|Bacteroidetes	DM	Type IX secretion system membrane protein PorP/SprF	sprD	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF,SPOR
k59_583559_2	317025.Tcr_1455	3.4e-127	365.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,462H6@72273|Thiotrichales	72273|Thiotrichales	M	Cytidylyltransferase	-	-	2.7.7.43,2.7.7.82	ko:K00983,ko:K18431	ko00520,ko01100,map00520,map01100	-	R01117,R04215,R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_865876_1	1121007.AUML01000004_gene2477	1.17e-24	96.3	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1I40T@117743|Flavobacteriia,2YJK9@290174|Aquimarina	976|Bacteroidetes	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k59_865876_2	1120965.AUBV01000007_gene2516	4.19e-26	101.0	28Q4Y@1|root,2ZCN1@2|Bacteria,4NRPX@976|Bacteroidetes,47P9K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_583568_1	1121931.AUHG01000018_gene1329	1.44e-111	348.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_921823_1	1137281.D778_00281	2.45e-189	529.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1HY93@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_921823_2	1137281.D778_00282	9.66e-85	265.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1HX1F@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde	-	-	1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220	-	R00264,R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_1770392_1	1178825.ALIH01000043_gene2258	7.3e-97	298.0	COG2304@1|root,COG2304@2|Bacteria,4NIIS@976|Bacteroidetes,1I0TX@117743|Flavobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1147369_1	323850.Shew_3456	8.66e-130	376.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,2Q8MM@267890|Shewanellaceae	1236|Gammaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
k59_1770422_1	1484460.JSWG01000015_gene1065	8.17e-173	509.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_1318955_1	985255.APHJ01000021_gene1558	8.67e-99	307.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1HXD4@117743|Flavobacteriia,2P5T5@244698|Gillisia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_1090841_1	153948.NAL212_0069	2.24e-79	251.0	COG1479@1|root,COG1479@2|Bacteria,1R63V@1224|Proteobacteria,2VTJA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
k59_583609_1	90814.KL370891_gene709	6.98e-05	45.1	COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,461DG@72273|Thiotrichales	72273|Thiotrichales	N	PFAM flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
k59_583609_2	1123514.KB905899_gene1426	3.91e-67	207.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,460RD@72273|Thiotrichales	72273|Thiotrichales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_583609_3	90814.KL370891_gene707	3.32e-221	612.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,45ZXB@72273|Thiotrichales	72273|Thiotrichales	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_583609_4	90814.KL370891_gene706	3.54e-78	239.0	COG1580@1|root,COG1580@2|Bacteria,1N2N9@1224|Proteobacteria,1SAF0@1236|Gammaproteobacteria,461D5@72273|Thiotrichales	72273|Thiotrichales	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_921878_1	929558.SMGD1_0411	5.58e-75	236.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,42PMY@68525|delta/epsilon subdivisions,2YMBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_1090848_1	1121931.AUHG01000010_gene453	6.49e-124	362.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HY65@117743|Flavobacteriia	976|Bacteroidetes	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k59_1487692_1	1380600.AUYN01000003_gene122	0.0	949.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1487692_4	1178825.ALIH01000012_gene1817	1.04e-43	142.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,1I50I@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
k59_471367_1	1249975.JQLP01000008_gene315	1.42e-66	204.0	2A98Z@1|root,30YDT@2|Bacteria,4NNZN@976|Bacteroidetes,1I2JP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_IS630,HTH_psq
k59_188930_1	1415778.JQMM01000001_gene2189	1.29e-52	181.0	2DBNG@1|root,2ZA3W@2|Bacteria,1P5DN@1224|Proteobacteria,1T4B9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_414263_1	1137281.D778_00189	1.71e-58	181.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1I3VJ@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal subunit interface protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k59_414263_2	1380600.AUYN01000001_gene2742	6.41e-163	461.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1HWMN@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_414263_4	1178825.ALIH01000017_gene674	3.44e-248	685.0	COG1960@1|root,COG1960@2|Bacteria,4NFD4@976|Bacteroidetes,1HWQD@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_414263_5	1380600.AUYN01000001_gene2745	3.84e-134	387.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1HX4K@117743|Flavobacteriia	976|Bacteroidetes	L	COG1555 DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
k59_414263_6	1121011.AUCB01000016_gene3958	2.01e-14	66.6	2AC84@1|root,311ST@2|Bacteria,4PGN8@976|Bacteroidetes,1IFQB@117743|Flavobacteriia,23IG5@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_414263_7	1121897.AUGO01000001_gene1467	1.12e-148	434.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1IFBS@117743|Flavobacteriia,2NVEG@237|Flavobacterium	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
k59_527069_1	90814.KL370891_gene506	3.26e-48	162.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_527069_2	90814.KL370891_gene505	5.29e-40	140.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,45ZN2@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_810132_1	1219077.VAZ01S_021_00010	2.74e-86	265.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XTZN@135623|Vibrionales	135623|Vibrionales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_810132_2	317025.Tcr_1513	1.31e-88	274.0	2AAYF@1|root,310BX@2|Bacteria,1RESE@1224|Proteobacteria,1S5GS@1236|Gammaproteobacteria,461XC@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131312_1	1565129.JSFF01000039_gene3277	3.32e-29	109.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,2Q9PJ@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
k59_131312_2	1565129.JSFF01000039_gene3276	2.76e-106	310.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,2QAE6@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
k59_1713821_1	927658.AJUM01000024_gene2588	8.62e-235	683.0	COG3537@1|root,COG3537@2|Bacteria,4NI5B@976|Bacteroidetes,2FMQ3@200643|Bacteroidia,3XK9T@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_1319019_1	479431.Namu_3019	5.08e-13	68.9	COG2310@1|root,COG2310@2|Bacteria,2GJ0Q@201174|Actinobacteria,4EU18@85013|Frankiales	201174|Actinobacteria	T	stress protein	-	-	-	ko:K05791,ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
k59_1147462_1	326298.Suden_0676	4.32e-111	344.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2YM9V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
k59_1770497_1	1123518.ARWI01000001_gene187	1.68e-137	400.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,45ZP0@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1713832_1	1178825.ALIH01000004_gene2892	3.28e-131	395.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,1HXJI@117743|Flavobacteriia	976|Bacteroidetes	P	cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_752572_1	1348657.M622_16070	5.12e-61	197.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,2KV1J@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_752572_2	1000565.METUNv1_01026	3.78e-29	108.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,2KW4U@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_1542965_2	1236541.BALL01000066_gene4751	1.14e-85	257.0	COG3381@1|root,COG3381@2|Bacteria,1NBZG@1224|Proteobacteria,1SD7S@1236|Gammaproteobacteria,2QBGN@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM cytoplasmic chaperone TorD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_1319046_1	1124780.ANNU01000032_gene1227	1.36e-45	170.0	COG3540@1|root,COG4677@1|root,COG3540@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	pel	-	3.1.1.11,3.1.4.3,3.2.1.82	ko:K01051,ko:K01114,ko:K10297,ko:K18650	ko00040,ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00040,map00562,map00564,map00565,map01100,map01110,map02024,map04919	M00081	R01312,R02027,R02052,R02362,R03332,R07381	RC00017,RC00425,RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko02042,ko04121	-	GH28	-	Beta_helix,Big_3,Pectinesterase,Pkinase
k59_17865_1	1479237.JMLY01000001_gene2908	0.000381	43.1	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,4650J@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	response regulator	rsbU	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
k59_17865_2	1279009.ADICEAN_03647	9.01e-15	79.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
k59_1430485_1	326298.Suden_0792	1.26e-06	49.3	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2YMC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1430485_2	1172190.M947_09625	1.23e-113	331.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2YN5P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_752596_1	1172190.M947_07735	6.31e-84	259.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2YME9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_752596_2	929558.SMGD1_1630	2.63e-37	133.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2YMGF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1430494_1	1353276.JADR01000008_gene886	2.06e-09	63.9	COG1538@1|root,COG1538@2|Bacteria,4NKWK@976|Bacteroidetes,1I4KR@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_414344_1	1123514.KB905903_gene399	1.62e-69	219.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RRJV@1236|Gammaproteobacteria,461X2@72273|Thiotrichales	72273|Thiotrichales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_414344_2	1123518.ARWI01000001_gene1809	4.19e-198	552.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,461J3@72273|Thiotrichales	72273|Thiotrichales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_414344_3	1123514.KB905903_gene401	9.3e-35	129.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,460TN@72273|Thiotrichales	72273|Thiotrichales	S	PFAM CobW HypB UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
k59_1487799_2	326298.Suden_1439	6.64e-59	186.0	COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,42RA4@68525|delta/epsilon subdivisions,2YNVU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1430509_1	90814.KL370891_gene1198	1.35e-93	279.0	COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,1S406@1236|Gammaproteobacteria,4627H@72273|Thiotrichales	72273|Thiotrichales	J	RNA pseudouridylate synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_583730_1	1121935.AQXX01000116_gene5183	2.8e-57	178.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,1XPP3@135619|Oceanospirillales	135619|Oceanospirillales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
k59_471490_1	1380600.AUYN01000009_gene987	1.71e-55	179.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k59_471490_2	946077.W5A_03909	7.11e-32	121.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1HWPI@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_866068_1	1286632.P278_22990	0.0	1348.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HZS7@117743|Flavobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_866068_2	1286632.P278_23000	1.87e-219	621.0	COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,1IJ9G@117743|Flavobacteriia	976|Bacteroidetes	F	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1601381_1	1123228.AUIH01000011_gene2070	2.66e-30	114.0	COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S9TM@1236|Gammaproteobacteria,1XKZG@135619|Oceanospirillales	135619|Oceanospirillales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_752633_1	153721.MYP_3256	1.27e-09	66.2	COG3903@1|root,COG5635@1|root,COG3903@2|Bacteria,COG5635@2|Bacteria,4NWG2@976|Bacteroidetes,47SQZ@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_245575_1	563040.Saut_1808	1.69e-07	50.8	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2YNW0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_245575_2	326298.Suden_1862	8.86e-90	265.0	2AHPN@1|root,3181V@2|Bacteria,1PZNU@1224|Proteobacteria,42QWU@68525|delta/epsilon subdivisions,2YMYS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF3972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3972
k59_245575_3	563040.Saut_1806	2.88e-46	157.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,42RA1@68525|delta/epsilon subdivisions,2YNYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k59_1543037_1	945713.IALB_1858	3.61e-35	137.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	MORN_2,Peptidase_C14,Pkinase,Sel1
k59_1430557_1	1249997.JHZW01000003_gene2707	3.36e-146	422.0	COG0526@1|root,COG0526@2|Bacteria,4NK8N@976|Bacteroidetes,1I84U@117743|Flavobacteriia,2PHWD@252356|Maribacter	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
k59_1770599_1	317025.Tcr_1865	1.3e-35	129.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RPGM@1236|Gammaproteobacteria,460YR@72273|Thiotrichales	72273|Thiotrichales	IQ	FolM Alternative dihydrofolate reductase 1	-	-	1.5.1.3,1.5.1.50	ko:K13938	ko00670,ko00790,ko01100,map00670,map00790,map01100	-	R00936,R00939,R11019	RC00109,RC03327	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
k59_1770599_2	317025.Tcr_1863	3.3e-161	460.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,460BX@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_1770599_3	1123514.KB905902_gene213	7.8e-73	224.0	COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,1SBKN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1487859_1	484018.BACPLE_02491	1.79e-10	60.5	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,2FPE5@200643|Bacteroidia,4AKF3@815|Bacteroidaceae	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_1487859_2	411154.GFO_2965	1.41e-47	153.0	2E33D@1|root,32Y3H@2|Bacteria,4NVRK@976|Bacteroidetes,1I502@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1487859_3	411154.GFO_2964	5.7e-80	243.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_1487875_1	90813.JQMT01000001_gene2049	1.24e-36	138.0	2CFU9@1|root,2Z9XM@2|Bacteria,1NBVN@1224|Proteobacteria,1SCY4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_245624_1	1123518.ARWI01000001_gene1318	3.35e-126	366.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,45ZRV@72273|Thiotrichales	72273|Thiotrichales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1035663_1	1121931.AUHG01000012_gene2846	3.03e-125	374.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_1430599_1	929558.SMGD1_2210	6.96e-130	389.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,42MHZ@68525|delta/epsilon subdivisions,2YNGC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA,TSP_3
k59_1657463_1	504487.JCM19302_2522	1.39e-60	194.0	COG0774@1|root,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_1657463_2	1197477.IA57_11660	4.11e-137	400.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_1657463_3	1121912.AUHD01000013_gene931	2.19e-70	226.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_1544508_1	1328313.DS2_18770	5.27e-86	275.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,464Q7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	amy	-	2.4.1.19	ko:K00701	ko00500,map00500	-	R11260	-	ko00000,ko00001,ko01000	-	CBM20,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_20
k59_1092656_1	667632.KB890164_gene1759	0.000943	42.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria,1K24U@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1728704_1	945713.IALB_0375	4.72e-82	257.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria	2|Bacteria	J	transcription antitermination	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_1728706_1	326298.Suden_0640	9.07e-109	337.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_767384_1	1121931.AUHG01000012_gene2678	1.15e-139	418.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1HWZI@117743|Flavobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_260866_1	504487.JCM19302_504	2.88e-95	287.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1HXQB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_881021_1	929558.SMGD1_0740	1.04e-172	502.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_881021_2	326298.Suden_0481	4.82e-50	169.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2YMXE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_260881_1	1121931.AUHG01000015_gene1175	1.65e-24	99.8	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_260881_2	411154.GFO_0432	1.48e-40	140.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_1617205_1	563040.Saut_0126	1.13e-124	377.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_203933_1	926562.Oweho_3400	5.21e-54	185.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
k59_1334857_1	96561.Dole_3203	6.51e-08	52.8	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MDC@68525|delta/epsilon subdivisions,2WJM7@28221|Deltaproteobacteria,2MHWR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102,2.6.1.109	ko:K13010,ko:K19715	ko00520,map00520	-	R10460,R11395	RC00006,RC00160,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_1334857_2	1178825.ALIH01000006_gene1532	1.79e-74	228.0	COG0778@1|root,COG0778@2|Bacteria,4NF4K@976|Bacteroidetes,1HY0I@117743|Flavobacteriia	976|Bacteroidetes	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_371885_1	1128427.KB904821_gene4032	8.8e-29	120.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
k59_1728753_1	1121896.JMLU01000002_gene462	3.21e-34	122.0	2DHE6@1|root,2ZZE1@2|Bacteria,4P0KQ@976|Bacteroidetes,1I8H9@117743|Flavobacteriia,2NZ4K@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1728753_2	376686.Fjoh_2518	1.56e-14	72.4	COG3642@1|root,COG3642@2|Bacteria,4NIJK@976|Bacteroidetes,1HZEK@117743|Flavobacteriia,2NT4C@237|Flavobacterium	976|Bacteroidetes	T	Pfam Lipopolysaccharide kinase (Kdo WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_714536_1	504487.JCM19302_4027	6.14e-62	191.0	COG1573@1|root,COG1573@2|Bacteria,4NG84@976|Bacteroidetes,1HXRH@117743|Flavobacteriia	976|Bacteroidetes	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
k59_881061_1	1123518.ARWI01000001_gene2419	4.76e-91	281.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1557818_1	1121931.AUHG01000010_gene243	1.9e-101	310.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,4NDVW@976|Bacteroidetes,1HXBF@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome C biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_1557818_2	1121931.AUHG01000010_gene244	4.89e-80	245.0	COG1209@1|root,COG1209@2|Bacteria,4PKUB@976|Bacteroidetes,1IJF6@117743|Flavobacteriia	976|Bacteroidetes	M	COG1209 dTDP-glucose pyrophosphorylase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k59_1503463_1	326298.Suden_0613	2.79e-22	103.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BUW@68525|delta/epsilon subdivisions,2YRCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_429493_1	1392490.JHZX01000001_gene1644	1.61e-27	103.0	COG3184@1|root,COG3184@2|Bacteria,4NQ9V@976|Bacteroidetes,1I3P7@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
k59_429493_2	1380600.AUYN01000007_gene3074	1.42e-64	206.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_260939_1	1123514.KB905899_gene1388	9.56e-102	300.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,460VZ@72273|Thiotrichales	72273|Thiotrichales	J	RNA pseudouridylate synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k59_1276220_1	411154.GFO_1980	8.94e-134	411.0	COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,4PMSQ@976|Bacteroidetes,1HZN0@117743|Flavobacteriia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,PAS_9,Response_reg
k59_655795_1	709032.Sulku_0289	8.07e-38	133.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2YNW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_655795_2	326298.Suden_1751	2.31e-173	486.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2YM9Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_826313_1	1172190.M947_10485	8.33e-55	181.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,42N3V@68525|delta/epsilon subdivisions,2YMBJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glutathionylspermidine synthase	gss	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k59_1162990_1	1238450.VIBNISOn1_1340025	1.85e-22	93.6	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1SB98@1236|Gammaproteobacteria,1Y2V0@135623|Vibrionales	135623|Vibrionales	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_1162990_2	279714.FuraDRAFT_1865	8.72e-18	82.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,2KTYQ@206351|Neisseriales	206351|Neisseriales	H	Belongs to the TPP enzyme family	-	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_989285_1	563040.Saut_1711	2.87e-05	46.6	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42RN6@68525|delta/epsilon subdivisions,2YP9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_989285_3	326298.Suden_1663	3.4e-08	55.1	COG2885@1|root,COG2885@2|Bacteria,1R9HA@1224|Proteobacteria,42T44@68525|delta/epsilon subdivisions,2YQQI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_597961_1	572480.Arnit_2406	1.37e-106	328.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2YMHZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_1617286_1	1452718.JBOY01000015_gene819	9.51e-27	109.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_1617286_2	94624.Bpet2160	2.99e-18	79.3	COG0662@1|root,COG0662@2|Bacteria,1RH1E@1224|Proteobacteria,2VSQU@28216|Betaproteobacteria,3T473@506|Alcaligenaceae	28216|Betaproteobacteria	G	COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_1388520_1	1565129.JSFF01000001_gene917	4.24e-48	161.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,2QAYF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH
k59_1388520_2	637905.SVI_1128	4.23e-40	140.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,2QAIU@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator, LysR family	gcvA	GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1049916_1	1172190.M947_03915	5.52e-60	194.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2YMBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_1049916_2	563040.Saut_1586	1.15e-38	131.0	COG3951@1|root,COG3951@2|Bacteria,1Q5W9@1224|Proteobacteria,42UQG@68525|delta/epsilon subdivisions,2YPWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MNO	Rod binding protein	flgJ	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
k59_1049916_3	929558.SMGD1_1932	4.23e-20	82.4	2AK6X@1|root,31AX3@2|Bacteria,1Q6DV@1224|Proteobacteria,432YY@68525|delta/epsilon subdivisions,2YSIQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Anti-sigma-28 factor, FlgM	-	-	-	-	-	-	-	-	-	-	-	-	FlgM
k59_1049916_4	929558.SMGD1_1933	4.72e-64	198.0	2AIM0@1|root,32I9V@2|Bacteria,1Q1S6@1224|Proteobacteria,42U9Z@68525|delta/epsilon subdivisions,2YPXP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90998_2	944546.ABED_2016	2.85e-48	166.0	2DKIW@1|root,309MK@2|Bacteria,1RF7C@1224|Proteobacteria,42T89@68525|delta/epsilon subdivisions,2YR98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
k59_1334972_1	1121931.AUHG01000017_gene1480	4.16e-48	157.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_1557932_1	411154.GFO_2806	4.4e-130	375.0	COG1834@1|root,COG1834@2|Bacteria,4NEUJ@976|Bacteroidetes,1HWNG@117743|Flavobacteriia	976|Bacteroidetes	E	Cytochrome C biogenesis protein CcmF	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k59_655871_1	985255.APHJ01000017_gene2182	1.21e-61	206.0	COG0417@1|root,COG0417@2|Bacteria,4NGEJ@976|Bacteroidetes,1HXZC@117743|Flavobacteriia,2P7PK@244698|Gillisia	976|Bacteroidetes	L	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1106145_1	1123514.KB905899_gene694	8.07e-34	119.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,4614M@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k59_1106145_2	90814.KL370891_gene832	2.02e-84	250.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4611H@72273|Thiotrichales	72273|Thiotrichales	I	Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_1334973_2	90813.JQMT01000001_gene223	2.53e-45	147.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,4613R@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_1334973_3	317025.Tcr_0303	3.58e-23	89.7	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,461CG@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_1334973_4	1123514.KB905899_gene1813	2.38e-64	197.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,460I6@72273|Thiotrichales	72273|Thiotrichales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_598001_2	1121931.AUHG01000010_gene488	8.37e-71	221.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k59_881175_1	929558.SMGD1_2277	3.97e-61	199.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2YMQG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_881175_2	709032.Sulku_0765	6.94e-05	45.4	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2YNYJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_261026_1	387093.SUN_0311	1.37e-54	189.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_1209772_2	929558.SMGD1_1106	0.000415	43.1	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2YPEZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cation efflux system protein	crdC	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
k59_881208_1	1121931.AUHG01000015_gene1295	4.05e-05	44.7	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes,1HWZH@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_881208_2	1121931.AUHG01000015_gene1294	1.29e-79	245.0	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes,1HWZH@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_261055_1	1476902.A0A067ZG47_9CAUD	1.63e-44	155.0	4QC7J@10239|Viruses,4R007@35237|dsDNA viruses  no RNA stage,4QSEV@28883|Caudovirales,4QJU7@10662|Myoviridae	10662|Myoviridae	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_936201_1	398579.Spea_3238	1.17e-86	265.0	COG3182@1|root,COG3182@2|Bacteria,1RHAR@1224|Proteobacteria,1S7MS@1236|Gammaproteobacteria,2QB1C@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PepSY-associated TM helix	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
k59_316930_1	1123518.ARWI01000001_gene608	1.7e-71	226.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462BB@72273|Thiotrichales	72273|Thiotrichales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1276343_1	929558.SMGD1_2281	3.19e-100	300.0	COG2204@1|root,COG2204@2|Bacteria,1QASN@1224|Proteobacteria,42RV2@68525|delta/epsilon subdivisions,2YP76@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activ_2,Sigma54_activat
k59_1276343_2	929558.SMGD1_2282	6.49e-185	518.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2YMWK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_1276343_3	929558.SMGD1_2283	5.29e-117	340.0	COG0388@1|root,COG0388@2|Bacteria,1RIQI@1224|Proteobacteria,42T6J@68525|delta/epsilon subdivisions,2YP46@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_91108_1	572480.Arnit_2532	1.77e-184	532.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2YMN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_1560044_1	572480.Arnit_2114	3.63e-149	430.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2YMAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_1505755_1	626887.J057_12536	1.64e-50	171.0	COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,4667T@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily	astE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009017,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_813,iECABU_c1320.ECABU_c20010,iECED1_1282.ECED1_1946,iECOK1_1307.ECOK1_1864,iECS88_1305.ECS88_1796,iUMN146_1321.UM146_08430,iUTI89_1310.UTI89_C1939,ic_1306.c2144	AstE_AspA
k59_1505755_2	1123228.AUIH01000013_gene210	5.05e-18	81.3	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XHZU@135619|Oceanospirillales	135619|Oceanospirillales	M	effector of murein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LrgB
k59_374078_1	563040.Saut_2101	1.59e-112	333.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_34446_1	572480.Arnit_0367	9e-38	134.0	COG3000@1|root,COG3000@2|Bacteria,1R763@1224|Proteobacteria,42TCS@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_34446_2	572480.Arnit_0368	2.29e-51	171.0	2CHB7@1|root,33V77@2|Bacteria,1NUG1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M75
k59_93209_1	411154.GFO_0719	4.45e-26	105.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1HYPN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_93209_2	411154.GFO_3003	1.18e-51	167.0	COG2930@1|root,COG2930@2|Bacteria,4NP71@976|Bacteroidetes,1I20I@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Family of	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_1674616_1	317025.Tcr_1409	3.49e-77	233.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,460KD@72273|Thiotrichales	72273|Thiotrichales	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_658060_1	1453500.AT05_09430	2.35e-92	282.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1505793_1	1380600.AUYN01000001_gene2749	4.37e-129	378.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1HWT2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
k59_1505793_2	1121875.KB907547_gene3498	1.74e-49	162.0	COG4635@1|root,COG4635@2|Bacteria,4NR5G@976|Bacteroidetes,1I32W@117743|Flavobacteriia	976|Bacteroidetes	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
k59_599665_1	1178825.ALIH01000001_gene2415	1.19e-96	284.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1I17F@117743|Flavobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_1447208_1	153721.MYP_1113	1.23e-72	224.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_1505796_1	1565314.OA34_11980	6.17e-58	194.0	COG0667@1|root,COG0667@2|Bacteria,1RK6Z@1224|Proteobacteria,42QDH@68525|delta/epsilon subdivisions,2YNCD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1505796_2	1537917.JU82_01015	2.62e-06	48.1	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1674623_1	563040.Saut_0268	1.15e-45	159.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	general secretion pathway protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_1674623_4	563040.Saut_0271	5e-47	160.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K10925	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_34471_1	1137281.D778_01349	7.38e-283	776.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_148472_1	1120951.AUBG01000011_gene2365	5.11e-75	253.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_1337228_1	1178825.ALIH01000001_gene2577	1.37e-53	179.0	290I6@1|root,2ZN71@2|Bacteria,4NM5S@976|Bacteroidetes,1I19E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1337228_2	1380600.AUYN01000009_gene1251	1.53e-90	276.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_1390768_1	929558.SMGD1_0130	3.33e-90	280.0	COG4773@1|root,COG4773@2|Bacteria,1QZ1U@1224|Proteobacteria,42PHE@68525|delta/epsilon subdivisions,2YN5J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	OprD
k59_1560123_1	1348657.M622_02470	1.98e-69	218.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,2KVDG@206389|Rhodocyclales	206389|Rhodocyclales	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_1560123_2	1348657.M622_02475	3.05e-40	135.0	COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,2VVPZ@28216|Betaproteobacteria,2KZCQ@206389|Rhodocyclales	206389|Rhodocyclales	K	MerR HTH family regulatory protein	-	-	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
k59_1062022_1	1380600.AUYN01000009_gene1324	1.08e-70	239.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2
k59_1176192_1	1565129.JSFF01000008_gene2688	8.72e-86	265.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,2Q948@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_1627197_1	929558.SMGD1_0013	7.13e-227	650.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YNH7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal,dCache_3
k59_1002335_1	504487.JCM19302_4019	1.29e-64	206.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
k59_1002335_2	1347342.BN863_34530	4.82e-51	172.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1HX0F@117743|Flavobacteriia	976|Bacteroidetes	O	collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1289477_1	323850.Shew_1811	1.93e-85	254.0	28I7M@1|root,2Z8AH@2|Bacteria,1N1DT@1224|Proteobacteria,1RYK3@1236|Gammaproteobacteria,2QAQQ@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ	zapC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0032153,GO:0042802,GO:0044464,GO:0050789,GO:0050794,GO:0051302,GO:0065007	-	ko:K18657	-	-	-	-	ko00000,ko03036	-	-	-	ZapC
k59_609466_1	944547.ABLL_1386	4.35e-31	120.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42N76@68525|delta/epsilon subdivisions,2YN3W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_609466_2	1355368.JART01000014_gene626	3.31e-30	108.0	COG2863@1|root,COG2863@2|Bacteria,1NFMX@1224|Proteobacteria,42VGD@68525|delta/epsilon subdivisions,2YPDJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1799446_1	1178825.ALIH01000007_gene1624	1.54e-99	292.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_781110_1	563040.Saut_1090	8.81e-54	188.0	COG2319@1|root,COG2319@2|Bacteria,1Q4XR@1224|Proteobacteria,42PRP@68525|delta/epsilon subdivisions,2YMZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_781118_1	1123518.ARWI01000001_gene2418	1.8e-37	134.0	COG2199@1|root,COG2199@2|Bacteria,1R4NG@1224|Proteobacteria,1S0XZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_4
k59_781118_2	90814.KL370891_gene1310	6.72e-62	193.0	COG1416@1|root,COG1416@2|Bacteria,1MZ46@1224|Proteobacteria,1SNE5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_1289534_1	945713.IALB_1985	1.13e-57	194.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1176287_1	62928.azo2052	7.2e-154	456.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,2KV02@206389|Rhodocyclales	206389|Rhodocyclales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1289541_1	1121931.AUHG01000011_gene1946	7.47e-83	252.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1289541_2	411154.GFO_2504	6.78e-40	145.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_1742651_1	1121288.AULL01000017_gene2466	9.5e-22	97.1	COG0463@1|root,COG0463@2|Bacteria,4NQNJ@976|Bacteroidetes,1I2VG@117743|Flavobacteriia,3ZRD1@59732|Chryseobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1685795_1	1380600.AUYN01000001_gene2678	5.57e-119	364.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_1176303_1	1172190.M947_11025	1.23e-159	471.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2YMH2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_609538_2	1336803.PHEL49_0921	1.78e-107	315.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1HWPS@117743|Flavobacteriia,3VVVS@52959|Polaribacter	976|Bacteroidetes	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_609538_3	313603.FB2170_05405	4.87e-55	187.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia,2PH7E@252356|Maribacter	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_44710_1	563040.Saut_1621	2.65e-97	287.0	COG3381@1|root,COG3381@2|Bacteria,1N4MX@1224|Proteobacteria,42RVB@68525|delta/epsilon subdivisions,2YP5X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	component of anaerobic	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_728045_1	1123514.KB905899_gene2007	6.06e-261	734.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_9
k59_781178_1	563040.Saut_1063	2.8e-157	467.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1221823_1	983544.Lacal_2372	3.85e-118	364.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k59_1062162_2	1191523.MROS_2390	5.84e-51	164.0	COG1993@1|root,COG1993@2|Bacteria	2|Bacteria	T	acr, cog1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
k59_1401048_1	886377.Murru_1453	3.72e-57	182.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia	976|Bacteroidetes	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_1401048_2	313603.FB2170_16826	5.68e-35	123.0	COG0219@1|root,COG0219@2|Bacteria,4NNTD@976|Bacteroidetes,1I1JC@117743|Flavobacteriia,2PHH1@252356|Maribacter	976|Bacteroidetes	J	SpoU rRNA Methylase family	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1627271_1	318167.Sfri_2082	7.68e-47	158.0	2DBY5@1|root,2ZBTE@2|Bacteria,1N0SW@1224|Proteobacteria,1S9CZ@1236|Gammaproteobacteria,2QBUX@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_609559_1	1380600.AUYN01000009_gene960	4.9e-254	711.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
k59_272398_1	518766.Rmar_0610	3.38e-35	134.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_158860_1	1123518.ARWI01000001_gene439	4.55e-39	133.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,460KM@72273|Thiotrichales	72273|Thiotrichales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_158860_2	90814.KL370891_gene857	7.86e-36	134.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1221850_1	411154.GFO_1638	5.19e-129	373.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1221850_2	411154.GFO_1639	1.23e-51	173.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
k59_1401066_1	1168067.JAGP01000001_gene1725	2.46e-92	276.0	COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,1RP91@1236|Gammaproteobacteria,460WI@72273|Thiotrichales	72273|Thiotrichales	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
k59_1401066_2	395493.BegalDRAFT_1804	1.74e-12	65.1	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RP5R@1236|Gammaproteobacteria,4601H@72273|Thiotrichales	72273|Thiotrichales	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
k59_669541_1	83406.HDN1F_15870	1.46e-23	93.6	COG2050@1|root,COG2050@2|Bacteria,1RITB@1224|Proteobacteria,1S63Z@1236|Gammaproteobacteria,1JB8T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_669541_2	1298593.TOL_2098	2.52e-31	115.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,1S6I1@1236|Gammaproteobacteria,1XS7P@135619|Oceanospirillales	135619|Oceanospirillales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1799573_1	504487.JCM19302_515	8.39e-75	238.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_609590_1	313603.FB2170_12431	4.24e-40	152.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia,2PGFR@252356|Maribacter	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M_N
k59_728093_1	504487.JCM19302_1075	1.68e-218	607.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_728093_2	1046627.BZARG_627	1.81e-63	207.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,1HWQW@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_272431_1	1172190.M947_11195	3.48e-99	301.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2YMFZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_1742744_1	1565129.JSFF01000003_gene2256	1.02e-100	304.0	COG4974@1|root,COG4974@2|Bacteria,1PZTE@1224|Proteobacteria,1RPTV@1236|Gammaproteobacteria,2QAHQ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_781244_1	497321.C664_09913	5.27e-117	350.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C
k59_385196_1	997884.HMPREF1068_01466	2.3e-125	385.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,4AK8A@815|Bacteroidaceae	976|Bacteroidetes	G	glycosyl hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_158916_1	85643.Tmz1t_2679	2.89e-50	174.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,2KVHB@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_839026_1	326298.Suden_0098	1.06e-68	219.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_839026_2	563040.Saut_1939	2.69e-90	271.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2YMWJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pyruvate ferredoxin oxidoreductase	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_161403_2	492774.JQMB01000004_gene1902	4.25e-22	95.1	COG3703@1|root,COG3703@2|Bacteria,1RAU0@1224|Proteobacteria,2U5VN@28211|Alphaproteobacteria,4BAVW@82115|Rhizobiaceae	2|Bacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
k59_1064797_1	929558.SMGD1_2737	2.83e-45	154.0	COG0810@1|root,COG0810@2|Bacteria,1PEYQ@1224|Proteobacteria,42WJI@68525|delta/epsilon subdivisions,2YQ9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
k59_1064797_2	326298.Suden_1993	6.7e-117	347.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2YN30@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_672262_1	572480.Arnit_0155	1.24e-101	303.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2YN3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_1519945_1	449447.MAE_04570	2.29e-25	97.8	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_784123_1	90814.KL370891_gene515	9.38e-154	441.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,460BB@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_1064805_1	113355.CM001775_gene123	7.59e-21	85.1	COG1813@1|root,COG1813@2|Bacteria,1GQS1@1117|Cyanobacteria	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_896074_1	1237149.C900_04383	1.57e-47	168.0	COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,47KBE@768503|Cytophagia	976|Bacteroidetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TPR_16,TPR_2,TPR_8
k59_1688548_1	1469557.JSWF01000028_gene3013	3.6e-195	549.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1688548_2	1227266.HMPREF1551_02209	2.54e-11	62.8	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,1EQ6S@1016|Capnocytophaga	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1802292_1	62928.azo2059	6.42e-88	266.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,2KUK0@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_107415_1	1123518.ARWI01000001_gene2472	1.49e-47	173.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_612134_1	929558.SMGD1_2640	1.5e-104	329.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_107423_1	1353529.M899_2864	4.9e-30	112.0	COG2128@1|root,COG2128@2|Bacteria,1N1YR@1224|Proteobacteria,431GZ@68525|delta/epsilon subdivisions,2WWGY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_107423_2	387093.SUN_1500	5.97e-74	244.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YTDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1351213_1	357804.Ping_1204	8.15e-30	125.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1NQKX@1224|Proteobacteria,1T32J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_3
k59_1351213_2	760192.Halhy_4363	1.83e-07	53.9	COG2197@1|root,COG2197@2|Bacteria,4NF5P@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_388034_1	1353537.TP2_03445	4.24e-40	142.0	COG1609@1|root,COG1609@2|Bacteria,1P1Q3@1224|Proteobacteria,2TSER@28211|Alphaproteobacteria,2XMY4@285107|Thioclava	28211|Alphaproteobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k59_784177_1	411154.GFO_0761	3.18e-32	121.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1IJ8Q@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_784177_2	1121931.AUHG01000016_gene1037	6.47e-98	288.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_333071_1	1123518.ARWI01000001_gene2049	7.1e-87	258.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,460D8@72273|Thiotrichales	72273|Thiotrichales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_333071_2	90814.KL370891_gene1607	1.7e-57	188.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,45ZWU@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM KamA family protein	epmB	-	-	ko:K19810	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_220116_1	1165841.SULAR_03782	2.5e-35	137.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_672340_1	411154.GFO_2278	1.43e-44	151.0	COG3642@1|root,COG3642@2|Bacteria,4NIJK@976|Bacteroidetes,1HZEK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Lipopolysaccharide kinase (Kdo WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
k59_672340_2	411154.GFO_2277	1.73e-63	204.0	COG1887@1|root,COG1887@2|Bacteria,4NG3J@976|Bacteroidetes,1HX8N@117743|Flavobacteriia	976|Bacteroidetes	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2,Glyphos_transf
k59_1351246_1	425104.Ssed_1788	5.64e-52	181.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,1RZIM@1236|Gammaproteobacteria,2Q8SU@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_730938_1	326298.Suden_1460	6.26e-30	110.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2YNZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_730938_2	929558.SMGD1_0450	2.64e-41	151.0	COG0642@1|root,COG0642@2|Bacteria,1QZ2C@1224|Proteobacteria,42QBR@68525|delta/epsilon subdivisions,2YNQB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_2,sCache_2
k59_107456_1	1121931.AUHG01000011_gene1769	6.87e-99	290.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1I2EF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_1520036_1	468059.AUHA01000002_gene49	4.47e-11	63.9	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1IT61@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1460255_1	563040.Saut_0949	7.66e-42	141.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2YNWN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FG	HIT family	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_1460255_2	1249480.B649_03270	1.29e-20	92.4	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_388083_1	572480.Arnit_2268	3.76e-71	233.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PF9@68525|delta/epsilon subdivisions,2YNH8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_274759_1	1121012.AUKX01000011_gene2340	1.71e-08	61.6	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia,23GAV@178469|Arenibacter	976|Bacteroidetes	EM	Lysin motif	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
k59_1403394_1	929558.SMGD1_2184	3.01e-77	236.0	COG2191@1|root,COG2191@2|Bacteria,1RD60@1224|Proteobacteria,42SP8@68525|delta/epsilon subdivisions,2YPEF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Formylmethanofuran dehydrogenase, subunit e	-	-	-	-	-	-	-	-	-	-	-	-	FmdE
k59_1573245_1	1250005.PHEL85_0894	3.85e-299	850.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia,3VVMQ@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1460275_1	313606.M23134_07704	3.15e-35	144.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_796889_1	411154.GFO_1802	1.56e-47	160.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_796889_2	1121931.AUHG01000017_gene1500	1.63e-14	72.4	COG4399@1|root,COG4399@2|Bacteria,4PM7W@976|Bacteroidetes,1HX9F@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_1530619_1	929556.Solca_1227	7.82e-75	247.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_1474207_1	929558.SMGD1_1177	1.53e-65	212.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_344322_1	929558.SMGD1_0444	6.86e-160	466.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_344322_2	929558.SMGD1_0443	1.25e-98	291.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42RBT@68525|delta/epsilon subdivisions,2YNWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_344322_3	1537917.JU82_05810	1.31e-08	55.1	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2YN92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_684187_1	313594.PI23P_01992	6.13e-86	265.0	28N5P@1|root,2ZBAU@2|Bacteria,4NKXZ@976|Bacteroidetes,1I05C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_909542_1	572480.Arnit_0119	1.35e-20	88.2	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_909542_2	572480.Arnit_0120	6.07e-66	221.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU6Y@1224|Proteobacteria,42M5I@68525|delta/epsilon subdivisions,2YN4K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	D-lactate dehydrogenase	dld	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
k59_1022901_1	985255.APHJ01000054_gene1934	8.73e-112	330.0	COG1960@1|root,COG1960@2|Bacteria,4NFD4@976|Bacteroidetes,1HWQD@117743|Flavobacteriia,2P5QS@244698|Gillisia	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1247992_1	1172190.M947_05430	5e-94	285.0	2AIMJ@1|root,3193W@2|Bacteria,1Q1QU@1224|Proteobacteria,42U73@68525|delta/epsilon subdivisions,2YSXF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1247992_2	760154.Sulba_0884	3.29e-21	86.7	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TP9@68525|delta/epsilon subdivisions,2YQ4J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_62544_1	1380600.AUYN01000009_gene1372	5.24e-268	748.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia	976|Bacteroidetes	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_344334_1	1392488.JHZY01000002_gene467	1.47e-74	244.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia,2XI9W@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_570760_1	411154.GFO_1039	4.9e-151	434.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
k59_684211_1	1283300.ATXB01000001_gene1160	7.62e-15	72.8	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,1SEPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_740137_1	1250278.JQNQ01000001_gene1730	1.85e-49	170.0	COG2031@1|root,COG2031@2|Bacteria,4NIRP@976|Bacteroidetes,1HWM3@117743|Flavobacteriia	976|Bacteroidetes	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
k59_740137_2	411154.GFO_0739	3.07e-100	294.0	29EPR@1|root,32V5P@2|Bacteria,4NSSE@976|Bacteroidetes,1I4C0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1305618_1	1137281.D778_02420	5.48e-100	303.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_966188_1	1121931.AUHG01000015_gene1304	4.79e-78	251.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_966188_2	411154.GFO_0591	4.95e-110	323.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_344355_1	323850.Shew_1047	4.66e-69	223.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,2Q9R1@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899	FAD_binding_2,Succ_DH_flav_C
k59_344355_2	425104.Ssed_1140	1e-27	107.0	2AIDR@1|root,318V5@2|Bacteria,1QE00@1224|Proteobacteria,1TA9H@1236|Gammaproteobacteria,2QCEZ@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	Cpta_toxin
k59_344362_1	396588.Tgr7_1428	1.97e-27	103.0	2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,1SSSK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1644238_1	317025.Tcr_1150	1.66e-162	503.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,45ZZR@72273|Thiotrichales	72273|Thiotrichales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
k59_1418049_1	999419.HMPREF1077_03607	1.87e-80	249.0	COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes,2FM6R@200643|Bacteroidia,22WCE@171551|Porphyromonadaceae	976|Bacteroidetes	C	Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1587890_1	63737.Npun_F2181	1.82e-37	147.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k59_1530699_1	545276.KB898733_gene2552	1.45e-14	73.2	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1X04J@135613|Chromatiales	135613|Chromatiales	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1530699_2	367737.Abu_0660	1.61e-24	103.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_1135414_1	504487.JCM19302_510	3.58e-123	359.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1HY61@117743|Flavobacteriia	976|Bacteroidetes	E	Acetylornithine deacetylase	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_627464_1	411154.GFO_2265	6.6e-104	324.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1135415_1	1121931.AUHG01000017_gene1548	9.83e-51	168.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_1135415_2	411154.GFO_1754	5.52e-54	174.0	COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1HWKN@117743|Flavobacteriia	976|Bacteroidetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_118871_1	1380600.AUYN01000009_gene1762	1.02e-172	489.0	28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,1HYW5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118871_2	1189620.AJXL01000022_gene2908	3.39e-101	302.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,1HZVI@117743|Flavobacteriia,2NTK9@237|Flavobacterium	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118871_3	1178825.ALIH01000001_gene2655	7.79e-283	785.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_288480_1	1282361.ABAC402_05830	9.12e-05	43.9	COG3795@1|root,COG3795@2|Bacteria,1RJJG@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k59_798617_1	1250232.JQNJ01000001_gene1811	6.46e-21	90.1	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,1I089@117743|Flavobacteriia	976|Bacteroidetes	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_798617_2	1223410.KN050846_gene2370	2.13e-51	172.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,1HZ4R@117743|Flavobacteriia	976|Bacteroidetes	O	AIR synthase related protein, N-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_64209_2	929558.SMGD1_1949	2.34e-63	202.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2YMD0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ADP-L-glycero-D-manno-heptose-6-epimerase	waaD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_345926_1	862908.BMS_0286	6.74e-05	48.9	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_1191736_1	1122225.AULQ01000001_gene1796	1.46e-35	125.0	2CT98@1|root,32SSW@2|Bacteria,4NSGA@976|Bacteroidetes,1I40N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
k59_1191736_2	1347342.BN863_14610	1.8e-46	159.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1645873_1	1178825.ALIH01000015_gene1869	4.85e-155	456.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HY58@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1645873_2	1380600.AUYN01000001_gene2338	1.41e-38	133.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1I2V8@117743|Flavobacteriia	976|Bacteroidetes	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_1024568_1	1380600.AUYN01000007_gene3205	1.12e-55	188.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1024568_2	1178825.ALIH01000003_gene2191	6.49e-74	233.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1HXWF@117743|Flavobacteriia	976|Bacteroidetes	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k59_854308_1	1172190.M947_09740	1.66e-128	373.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2YMHG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_1362390_1	1172190.M947_03745	3.03e-84	272.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2YMAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1080007_1	1121931.AUHG01000010_gene804	6.75e-62	196.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.30,1.1.1.401	ko:K00019,ko:K21883	ko00051,ko00072,ko00650,ko01100,ko01120,map00051,map00072,map00650,map01100,map01120	M00088	R01361,R11339	RC00089,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_1080007_2	1121931.AUHG01000010_gene805	4.14e-11	62.4	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HWPQ@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_1475943_1	305700.B447_14164	2.52e-112	336.0	COG2252@1|root,COG2252@2|Bacteria,1QU00@1224|Proteobacteria,2VPBD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permease family	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
k59_1532152_2	1123518.ARWI01000001_gene1925	3.24e-91	272.0	COG4567@1|root,COG4567@2|Bacteria,1QVWT@1224|Proteobacteria,1T2M1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg
k59_911127_1	1123518.ARWI01000001_gene1678	3.13e-15	72.4	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,460I5@72273|Thiotrichales	72273|Thiotrichales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_911127_2	90814.KL370892_gene1949	6.74e-66	212.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,460H3@72273|Thiotrichales	72273|Thiotrichales	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_854323_1	411154.GFO_1069	7.52e-72	221.0	COG0657@1|root,COG0657@2|Bacteria,4PKUU@976|Bacteroidetes,1IJFX@117743|Flavobacteriia	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_854323_2	411154.GFO_1070	5.66e-18	82.4	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_1249756_1	90814.KL370891_gene1117	3.26e-140	414.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,4601A@72273|Thiotrichales	72273|Thiotrichales	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_1249756_2	1123514.KB905899_gene966	3.35e-07	52.8	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,46167@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k59_1532162_1	1123228.AUIH01000024_gene3258	1.87e-123	387.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_290084_1	1054213.HMPREF9946_05105	7.61e-47	163.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2JPMU@204441|Rhodospirillales	204441|Rhodospirillales	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_629095_2	714943.Mucpa_2767	2.92e-55	183.0	COG4733@1|root,COG4733@2|Bacteria,4NQRS@976|Bacteroidetes	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_629095_3	1121875.KB907547_gene2864	6.84e-51	203.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
k59_1362417_1	411154.GFO_1607	2.97e-123	361.0	COG0304@1|root,COG0304@2|Bacteria,4NDXP@976|Bacteroidetes,1HXYM@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1080040_1	1565129.JSFF01000001_gene1052	8.74e-110	322.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,1RNDV@1236|Gammaproteobacteria,2QAEH@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_459845_1	589865.DaAHT2_0789	2.94e-61	197.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,42WJ3@68525|delta/epsilon subdivisions,2X5E1@28221|Deltaproteobacteria,2MKUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_345993_2	317025.Tcr_0692	5.52e-25	100.0	2DPF2@1|root,331TI@2|Bacteria,1NCIB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_403188_1	411154.GFO_3172	1.67e-107	332.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_1589628_1	1150621.SMUL_1228	5.96e-07	50.8	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,42M0F@68525|delta/epsilon subdivisions,2YNAP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheW,dCache_1
k59_1589628_2	709032.Sulku_1542	6.3e-67	209.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,430YU@68525|delta/epsilon subdivisions,2YS1X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1589628_4	1537917.JU82_10415	1.26e-90	276.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_515640_1	929558.SMGD1_2778	2.59e-89	275.0	COG2199@1|root,COG3706@2|Bacteria,1Q5A3@1224|Proteobacteria,430W0@68525|delta/epsilon subdivisions,2YRZB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1758979_1	1380600.AUYN01000002_gene4	2.67e-192	592.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
k59_629135_1	1123514.KB905899_gene1587	5.48e-115	337.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,460Q3@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_1645957_1	1484460.JSWG01000015_gene1108	6.29e-26	105.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1HX17@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_1645957_2	504487.JCM19302_19	4.15e-120	347.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1645957_3	983544.Lacal_2950	1.48e-89	275.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,4PKKU@976|Bacteroidetes,1IJC1@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
k59_1702279_1	305700.B447_09413	8.14e-06	47.4	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_1702279_2	1210884.HG799464_gene10366	1.58e-28	116.0	COG5433@1|root,COG5433@2|Bacteria,2IWUI@203682|Planctomycetes	203682|Planctomycetes	L	COG5433 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_120479_1	1250232.JQNJ01000001_gene820	6.37e-58	186.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1HZJ2@117743|Flavobacteriia	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_120479_2	1484460.JSWG01000001_gene2161	1.4e-77	237.0	COG2318@1|root,COG2318@2|Bacteria,4NQ7Y@976|Bacteroidetes,1I386@117743|Flavobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_120479_3	411154.GFO_0513	2.23e-35	131.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1136938_1	1123518.ARWI01000001_gene2183	3.27e-153	453.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T239@1236|Gammaproteobacteria,461MW@72273|Thiotrichales	72273|Thiotrichales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_233988_1	1232410.KI421419_gene2483	6.56e-84	275.0	COG0464@1|root,COG0466@1|root,COG0464@2|Bacteria,COG0466@2|Bacteria,1R9P6@1224|Proteobacteria,42PYU@68525|delta/epsilon subdivisions,2WJW7@28221|Deltaproteobacteria,43UBN@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Lon_C
k59_1136943_1	929558.SMGD1_1686	4.08e-101	313.0	COG1034@1|root,COG1034@2|Bacteria,1RCFT@1224|Proteobacteria,42NK4@68525|delta/epsilon subdivisions,2YNI6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4_10,Molybdopterin,NADH-G_4Fe-4S_3
k59_798755_1	1121931.AUHG01000011_gene2229	3.2e-42	148.0	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,1HX78@117743|Flavobacteriia	976|Bacteroidetes	S	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
k59_131990_2	675815.VOA_001693	6.7e-33	125.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1XWM1@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_189636_1	572480.Arnit_2359	4.18e-54	182.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_189636_2	572480.Arnit_2360	1.24e-78	242.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
k59_866708_1	1380600.AUYN01000001_gene2425	0.000668	41.6	COG0811@1|root,COG0811@2|Bacteria,4NVQH@976|Bacteroidetes,1I40C@117743|Flavobacteriia	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_866708_2	1121912.AUHD01000011_gene714	1.99e-35	130.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_472194_1	326298.Suden_1688	1.5e-48	164.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42M7C@68525|delta/epsilon subdivisions,2YTS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_472194_2	929558.SMGD1_1461	6.48e-116	340.0	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions,2YR4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_641328_1	1117647.M5M_04675	9.46e-14	71.2	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1J4NG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_641328_2	85643.Tmz1t_3802	1.23e-48	164.0	COG0451@1|root,COG1898@1|root,COG0451@2|Bacteria,COG1898@2|Bacteria,1MXGB@1224|Proteobacteria,2VKJ6@28216|Betaproteobacteria,2KVK8@206389|Rhodocyclales	206389|Rhodocyclales	GM	NAD dependent epimerase/dehydratase family	-	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_189645_1	411154.GFO_0154	3.53e-100	306.0	2C5U1@1|root,2Z80K@2|Bacteria,4NG4G@976|Bacteroidetes,1HZNR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_132012_1	1123228.AUIH01000040_gene2917	8.05e-68	210.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XHIV@135619|Oceanospirillales	135619|Oceanospirillales	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_18503_1	317025.Tcr_0260	1.91e-22	99.0	29MRQ@1|root,308PH@2|Bacteria,1QSJ0@1224|Proteobacteria,1RW0K@1236|Gammaproteobacteria,4631N@72273|Thiotrichales	72273|Thiotrichales	S	Type II secretion system (T2SS), protein N	-	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
k59_18503_2	1123514.KB905903_gene419	5.75e-41	142.0	COG3149@1|root,COG3149@2|Bacteria,1PSQ6@1224|Proteobacteria,1SX0E@1236|Gammaproteobacteria,462Z4@72273|Thiotrichales	72273|Thiotrichales	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k59_357603_1	929558.SMGD1_2676	1.36e-81	252.0	COG0770@1|root,COG0770@2|Bacteria,1Q5GZ@1224|Proteobacteria,42RQ8@68525|delta/epsilon subdivisions,2YP4M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	-	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_922611_1	572480.Arnit_1198	5.78e-143	408.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42NFK@68525|delta/epsilon subdivisions,2YNKJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1771221_1	90814.KL370891_gene1656	4.49e-24	92.8	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,460ZG@72273|Thiotrichales	72273|Thiotrichales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_1771221_2	1168067.JAGP01000001_gene597	1.63e-95	283.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,460D7@72273|Thiotrichales	72273|Thiotrichales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_18511_1	572480.Arnit_0243	1.5e-122	355.0	COG2204@1|root,COG2204@2|Bacteria,1QUIV@1224|Proteobacteria,42M4N@68525|delta/epsilon subdivisions,2YMIT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_76857_1	563040.Saut_0980	9.79e-13	67.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YR2H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COGs COG0643 Chemotaxis protein histidine kinase and related kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_76857_3	443144.GM21_1280	1.86e-32	129.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,43STW@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp34H-7	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_4,dCache_1
k59_189674_2	1121931.AUHG01000010_gene448	1.81e-77	233.0	COG3090@1|root,COG3090@2|Bacteria,4NNRW@976|Bacteroidetes,1I24H@117743|Flavobacteriia	976|Bacteroidetes	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_246235_1	929558.SMGD1_1699	4.92e-77	237.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_246235_2	563040.Saut_0388	5.09e-61	191.0	2AI7Y@1|root,318NF@2|Bacteria,1Q0NR@1224|Proteobacteria,42SAU@68525|delta/epsilon subdivisions,2YPMQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1543591_1	1123514.KB905899_gene1955	9.35e-107	330.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_357630_1	1165841.SULAR_06938	1.04e-68	209.0	COG1145@1|root,COG1145@2|Bacteria,1QZ2K@1224|Proteobacteria,42SFI@68525|delta/epsilon subdivisions,2YPQC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
k59_922640_1	572480.Arnit_0043	2.1e-16	73.6	COG3585@1|root,COG3585@2|Bacteria,1N06J@1224|Proteobacteria,42U4N@68525|delta/epsilon subdivisions,2YQ5D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
k59_922640_2	1355374.JARU01000020_gene954	2.38e-62	198.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2YNG3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_1321902_1	1219077.VAZ01S_051_00090	0.000291	42.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XT71@135623|Vibrionales	135623|Vibrionales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etfD	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
k59_1321902_2	1454004.AW11_00942	1.53e-47	170.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1KQCN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_1545508_1	761193.Runsl_1645	4.59e-18	89.4	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
k59_359460_1	983544.Lacal_0152	1.29e-25	101.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k59_359460_2	1484460.JSWG01000001_gene2401	1.2e-07	53.1	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_20383_1	1232410.KI421424_gene1655	1.17e-62	206.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,43S2C@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
k59_248248_1	411154.GFO_1029	3.23e-58	201.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_924489_1	411154.GFO_1052	9.57e-34	125.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1HXH7@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k59_924489_2	411154.GFO_1051	5.89e-31	115.0	COG3187@1|root,COG3187@2|Bacteria,4PM9Z@976|Bacteroidetes,1I1ZS@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF4377)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4377
k59_1604296_1	411154.GFO_1819	2.77e-115	335.0	COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_586166_1	1348635.BBJY01000002_gene3631	1.82e-41	146.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,1RN1B@1236|Gammaproteobacteria,1XW1S@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901682,GO:1902358	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
k59_700709_1	1250278.JQNQ01000001_gene86	2.69e-60	207.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1HYC9@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
k59_529926_2	1033736.CAHK01000013_gene906	3.86e-06	52.0	COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,4FADG@85019|Brevibacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
k59_868829_1	269796.Rru_A1566	5.15e-67	223.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,2JPUQ@204441|Rhodospirillales	204441|Rhodospirillales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
k59_1093608_1	1178825.ALIH01000005_gene234	8.64e-20	85.9	2AU1F@1|root,31JMK@2|Bacteria,4NQUW@976|Bacteroidetes,1I33E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_813339_1	411154.GFO_3131	2.32e-213	595.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia	976|Bacteroidetes	O	assembly protein, SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
k59_359491_1	1168067.JAGP01000001_gene15	5.94e-62	209.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1MZV7@1224|Proteobacteria,1T2ME@1236|Gammaproteobacteria,4612M@72273|Thiotrichales	72273|Thiotrichales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_359491_2	1123518.ARWI01000001_gene1323	7.05e-06	46.6	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,460RE@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_1545577_1	929558.SMGD1_1036	2.05e-68	222.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2YNJG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_1604339_1	620914.JH621247_gene3071	2.48e-53	169.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia,2YJVI@290174|Aquimarina	976|Bacteroidetes	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_1604339_2	1353276.JADR01000003_gene2861	1.11e-164	464.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1HXQR@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_304331_1	1121931.AUHG01000012_gene2526	1.27e-06	49.7	COG0457@1|root,COG0457@2|Bacteria,4PKJM@976|Bacteroidetes,1IJB0@117743|Flavobacteriia	976|Bacteroidetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
k59_304331_2	411154.GFO_1654	1.77e-75	250.0	COG4258@1|root,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
k59_529967_1	1537917.JU82_08675	1.29e-45	151.0	COG1699@1|root,COG1699@2|Bacteria,1N347@1224|Proteobacteria,42RNU@68525|delta/epsilon subdivisions,2YPKW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
k59_1604341_1	1298593.TOL_2066	6.28e-34	125.0	2C1VC@1|root,2Z83Q@2|Bacteria,1MV9V@1224|Proteobacteria,1S31Q@1236|Gammaproteobacteria,1XP61@135619|Oceanospirillales	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1490641_1	1123518.ARWI01000001_gene1381	3.59e-85	278.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	ko:K12063	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	EAL,GGDEF,HATPase_c,HisKA,Hpt,Response_reg
k59_359510_1	1121931.AUHG01000011_gene2173	4.74e-117	353.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
k59_1773399_1	1178825.ALIH01000001_gene2512	3.83e-61	202.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
k59_1716629_1	572480.Arnit_2333	2.21e-127	367.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2YMWK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_755137_1	1250232.JQNJ01000001_gene2486	2.88e-99	313.0	COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,1HZ2N@117743|Flavobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_8
k59_813392_1	1123514.KB905899_gene2039	1.01e-103	311.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,461PX@72273|Thiotrichales	72273|Thiotrichales	M	phospholipase A1	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_813392_2	1123518.ARWI01000001_gene1313	4.87e-29	110.0	COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,463NE@72273|Thiotrichales	72273|Thiotrichales	CH	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
k59_1093655_1	572480.Arnit_0424	9.43e-63	197.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2YNW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_530006_1	326298.Suden_2080	1.3e-177	507.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_755141_1	411154.GFO_2304	1.17e-111	333.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1HYUR@117743|Flavobacteriia	976|Bacteroidetes	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
k59_1376178_1	1121931.AUHG01000011_gene1738	7.02e-115	348.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1376178_2	1121931.AUHG01000011_gene1739	1.23e-74	227.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_755155_1	1123518.ARWI01000001_gene1711	1.01e-80	249.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales	72273|Thiotrichales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1038422_1	563040.Saut_2097	5.55e-49	167.0	COG3245@1|root,COG3258@1|root,COG3245@2|Bacteria,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,42WAQ@68525|delta/epsilon subdivisions,2YTG9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_1038422_2	563040.Saut_2098	2.08e-21	87.8	COG5501@1|root,COG5501@2|Bacteria,1PPTJ@1224|Proteobacteria,430CY@68525|delta/epsilon subdivisions,2YS07@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sulfur oxidation protein SoxY	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_304396_1	411154.GFO_2858	9.76e-126	362.0	COG0546@1|root,COG0546@2|Bacteria,4PM7Q@976|Bacteroidetes,1IJKU@117743|Flavobacteriia	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k59_304396_2	411154.GFO_2859	1.15e-22	95.9	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1716659_1	771875.Ferpe_0259	8.81e-06	52.8	COG3525@1|root,COG3525@2|Bacteria,2GBYK@200918|Thermotogae	200918|Thermotogae	G	PFAM glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
k59_530038_1	929558.SMGD1_0751	4.49e-74	232.0	COG0795@1|root,COG0795@2|Bacteria,1PXEK@1224|Proteobacteria,42MVG@68525|delta/epsilon subdivisions,2YN6F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	permease	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_530038_2	1172190.M947_02835	1.04e-39	136.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2YP7I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_474197_1	1123517.JOMR01000001_gene837	1.48e-20	89.7	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,461BZ@72273|Thiotrichales	72273|Thiotrichales	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_924620_1	1121918.ARWE01000001_gene2971	1.91e-30	116.0	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_924620_2	317025.Tcr_0935	1.21e-127	372.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,460RS@72273|Thiotrichales	72273|Thiotrichales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_304403_1	317025.Tcr_2056	0.0	1179.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,45ZWK@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_304403_2	317025.Tcr_2057	2.41e-19	86.3	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,461MS@72273|Thiotrichales	72273|Thiotrichales	G	PFAM Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_1264072_1	1178825.ALIH01000002_gene905	8.83e-31	116.0	COG2017@1|root,COG2017@2|Bacteria,4NKUK@976|Bacteroidetes,1I13Q@117743|Flavobacteriia	976|Bacteroidetes	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_1264072_2	1250005.PHEL85_3135	1.72e-53	179.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1HWZC@117743|Flavobacteriia,3VW7H@52959|Polaribacter	976|Bacteroidetes	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k59_530061_1	929558.SMGD1_0964	5.87e-26	103.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria	1224|Proteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1730462_2	342610.Patl_2569	2e-17	80.9	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,2Q06R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_92727_1	945713.IALB_1294	1.3e-16	81.3	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397,Mucin_bdg,Peptidase_M60,SLH
k59_92727_2	945713.IALB_3152	1.85e-18	86.3	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
k59_828037_2	257310.BB3958	1.97e-09	60.1	COG3836@1|root,COG3836@2|Bacteria,1R84K@1224|Proteobacteria,2VS1I@28216|Betaproteobacteria,3T7RF@506|Alcaligenaceae	28216|Betaproteobacteria	C	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
k59_1505302_1	1487953.JMKF01000004_gene691	7.78e-37	132.0	COG0500@1|root,COG2226@2|Bacteria,1G3RV@1117|Cyanobacteria,1H8Z1@1150|Oscillatoriales	1117|Cyanobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_882826_1	50960.LS81_08645	9.83e-60	197.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_882826_2	572480.Arnit_1543	5.15e-35	126.0	2BVAM@1|root,32QQF@2|Bacteria,1Q4S6@1224|Proteobacteria,42ZRM@68525|delta/epsilon subdivisions,2YRRP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_92745_1	313595.P700755_001148	6.77e-142	407.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes,1HYW8@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
k59_1559629_1	1121931.AUHG01000011_gene1659	4.47e-128	368.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HXMP@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
k59_1164760_1	1296415.JACC01000044_gene2743	9.35e-83	249.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia,2YHB8@290174|Aquimarina	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_1164760_2	1380600.AUYN01000006_gene791	7.05e-223	616.0	COG0208@1|root,COG0208@2|Bacteria,4NE91@976|Bacteroidetes,1HWJI@117743|Flavobacteriia	976|Bacteroidetes	F	fatty acid desaturase	desA1	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
k59_1164760_3	1380600.AUYN01000006_gene790	2.37e-63	197.0	COG0204@1|root,COG0204@2|Bacteria,4NHC8@976|Bacteroidetes,1HY24@117743|Flavobacteriia	976|Bacteroidetes	I	acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1561626_2	1286171.EAL2_c06960	4.51e-26	105.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia,25ZS6@186806|Eubacteriaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1052884_1	1172190.M947_00760	8.35e-19	86.3	COG2215@1|root,COG3683@1|root,COG2215@2|Bacteria,COG3683@2|Bacteria,1MX4D@1224|Proteobacteria,42PHI@68525|delta/epsilon subdivisions,2YM9S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1007,NicO
k59_1052884_2	929558.SMGD1_0340	1.59e-34	122.0	COG2143@1|root,COG2143@2|Bacteria	2|Bacteria	O	COG2143 Thioredoxin-related protein	soxS	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	Thioredoxin_2,Thioredoxin_7
k59_1732498_1	1223410.KN050846_gene901	1.94e-60	198.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_1732498_2	1122225.AULQ01000006_gene1041	1.8e-121	356.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_320604_1	983544.Lacal_0700	3e-108	335.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_659618_2	411154.GFO_2119	3.42e-21	89.4	28NNN@1|root,2ZBNU@2|Bacteria,4NMJD@976|Bacteroidetes,1I4NV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1212636_1	1123518.ARWI01000001_gene1906	4.68e-63	211.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales	72273|Thiotrichales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1338746_1	1123228.AUIH01000002_gene1605	8.32e-70	226.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XI3S@135619|Oceanospirillales	135619|Oceanospirillales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_1676207_1	929558.SMGD1_0101	5.6e-142	416.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PH5@68525|delta/epsilon subdivisions,2YMHH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1212674_1	945713.IALB_0216	1.49e-51	182.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_375628_1	1123517.JOMR01000001_gene846	1.22e-28	109.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,4600Q@72273|Thiotrichales	72273|Thiotrichales	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_375628_2	314278.NB231_10163	2.27e-33	119.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1X22S@135613|Chromatiales	135613|Chromatiales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
k59_375628_3	1123514.KB905899_gene1192	5.97e-49	157.0	2C3Q0@1|root,334WS@2|Bacteria,1NBS8@1224|Proteobacteria,1SE5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	IV02_14570	-	-	-	-	-	-	-	-	-	-	-	-
k59_375628_4	1121875.KB907549_gene1896	4.1e-33	125.0	COG0604@1|root,COG0604@2|Bacteria,4NJ5X@976|Bacteroidetes,1IIKA@117743|Flavobacteriia	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k59_94881_1	1137281.D778_00299	9.71e-105	332.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_94881_2	391603.FBALC1_04292	2.41e-37	133.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,1HY5M@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_1507456_1	323850.Shew_2083	1.56e-107	316.0	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1SZUE@1236|Gammaproteobacteria,2QASV@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_207799_1	945713.IALB_0304	1.58e-75	250.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
k59_1676261_2	1168065.DOK_03573	1.9e-32	127.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_36085_1	1121931.AUHG01000014_gene3079	8.3e-71	240.0	COG1345@1|root,COG3209@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-binding_MopE,DUF11,HYR,Laminin_G_3,PKD,SprB
k59_375649_1	411154.GFO_1044	4.64e-80	254.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1HXCS@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_490108_1	1353528.DT23_13380	1.32e-93	296.0	COG0025@1|root,COG0664@1|root,COG0025@2|Bacteria,COG0664@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na H antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
k59_264376_1	1163617.SCD_n02038	1.51e-41	148.0	COG0191@1|root,COG0191@2|Bacteria,1R6TC@1224|Proteobacteria,2VMUH@28216|Betaproteobacteria	28216|Betaproteobacteria	G	ketose-bisphosphate aldolase	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_1052987_1	411154.GFO_0018	1.51e-88	279.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
k59_375677_1	225937.HP15_460	1.94e-70	225.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,464TP@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_207833_1	566466.NOR53_946	1.47e-40	152.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1J4CD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_771234_1	504487.JCM19302_2833	2.83e-119	349.0	COG0296@1|root,COG0296@2|Bacteria,4NJ7Z@976|Bacteroidetes,1HZ6E@117743|Flavobacteriia	976|Bacteroidetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
k59_939177_1	563040.Saut_2113	1.62e-68	216.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,42TDF@68525|delta/epsilon subdivisions,2YP4F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Mannosyl-glycoprotein	-	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
k59_375692_1	1172190.M947_02635	8.78e-96	288.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0D@68525|delta/epsilon subdivisions,2YT4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_375692_2	1172190.M947_02630	2.42e-16	77.4	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2YMZ5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_718519_2	278963.ATWD01000001_gene3863	2.91e-50	169.0	COG1028@1|root,COG1028@2|Bacteria,3Y3FQ@57723|Acidobacteria,2JHPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1507525_1	411154.GFO_0956	3.32e-68	217.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_1507530_1	305700.B447_20408	2.07e-81	265.0	COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,2VHGG@28216|Betaproteobacteria,2KUZQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Family 2 glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17,Glyco_tranf_2_3,Glycos_transf_2
k59_601094_2	563040.Saut_0970	8.92e-42	145.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2YMEG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	polyphosphate kinase	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_264420_1	504487.JCM19302_3217	1.39e-174	494.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1HXNI@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1789852_1	1392489.JPOL01000002_gene2258	5.75e-105	310.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia,2XHZI@283735|Leeuwenhoekiella	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
k59_885061_1	323850.Shew_1698	3.9e-39	145.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,2Q9E0@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k59_885061_2	1236541.BALL01000001_gene61	2.85e-17	76.6	COG2716@1|root,COG2716@2|Bacteria,1NFZW@1224|Proteobacteria,1SCYR@1236|Gammaproteobacteria,2QBPE@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_4,ACT_6
k59_1280188_1	1165841.SULAR_01265	4.29e-06	48.5	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2YMU2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_718561_1	717772.THIAE_02750	1.67e-122	382.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9
k59_718561_2	1168067.JAGP01000001_gene1509	2.09e-60	195.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,4602Y@72273|Thiotrichales	72273|Thiotrichales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1280191_2	425104.Ssed_1323	3.9e-29	104.0	2CCBA@1|root,33EB7@2|Bacteria,1NHGG@1224|Proteobacteria,1SJ6R@1236|Gammaproteobacteria,2QCSX@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95025_1	1408473.JHXO01000011_gene2965	6.73e-06	48.1	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,2FM4X@200643|Bacteroidia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_95025_2	886379.AEWI01000007_gene817	1.08e-32	119.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,2FPJA@200643|Bacteroidia,3XK2I@558415|Marinilabiliaceae	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
k59_150220_1	1121931.AUHG01000011_gene1642	8.56e-143	405.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1HXNN@117743|Flavobacteriia	976|Bacteroidetes	Q	abc transporter (atp-binding protein)	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_150220_2	411154.GFO_2881	3.06e-17	78.2	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_207927_1	62928.azo2520	4.22e-16	73.9	COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2VT71@28216|Betaproteobacteria,2KYAH@206389|Rhodocyclales	206389|Rhodocyclales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_207927_2	62928.azo2519	1.03e-82	256.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,2KXYS@206389|Rhodocyclales	206389|Rhodocyclales	G	TRAP-type C4-dicarboxylate transport system, large permease	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_36219_1	326298.Suden_0740	1.45e-162	474.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42N29@68525|delta/epsilon subdivisions,2YMFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_718586_1	1123518.ARWI01000001_gene407	8.2e-73	224.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,45ZPR@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k59_718586_2	1123517.JOMR01000001_gene947	3.29e-48	157.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,46152@72273|Thiotrichales	72273|Thiotrichales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_718586_3	425104.Ssed_1835	2.29e-28	108.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,1RRVB@1236|Gammaproteobacteria,2Q9FA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
k59_1676404_2	1172190.M947_06345	3.89e-200	573.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,42PUG@68525|delta/epsilon subdivisions,2YN09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent copper receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_830216_1	317025.Tcr_0046	1.98e-52	173.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,1SBZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_830216_2	90813.JQMT01000001_gene2146	6.67e-120	345.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,460M0@72273|Thiotrichales	72273|Thiotrichales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_830216_3	317025.Tcr_0048	6.28e-37	138.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein Ccs1 ResB	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_36233_1	1172190.M947_10255	9.01e-37	137.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_36233_3	857087.Metme_3978	7.91e-08	54.3	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XFYS@135618|Methylococcales	135618|Methylococcales	NT	Signal transduction histidine kinase, phosphotransfer (Hpt) region	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1620973_1	1565129.JSFF01000003_gene2077	1.58e-66	210.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,2QAY0@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1732749_1	314230.DSM3645_05535	8.9e-49	170.0	COG0438@1|root,COG0438@2|Bacteria,2J252@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1507621_1	391603.FBALC1_06758	9.62e-40	138.0	COG3467@1|root,COG3467@2|Bacteria,4NQFR@976|Bacteroidetes,1I2TN@117743|Flavobacteriia	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
k59_1392523_1	572480.Arnit_0818	4.56e-06	47.8	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,43019@68525|delta/epsilon subdivisions,2YRSY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	LapD/MoxY periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
k59_1392523_2	572480.Arnit_0817	6.09e-77	254.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YNQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1212824_1	1279009.ADICEAN_00262	1.17e-30	125.0	COG1807@1|root,COG1807@2|Bacteria,4NZXF@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_320875_1	572480.Arnit_0668	9.28e-172	507.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2YMGZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1449010_1	317025.Tcr_1851	4.62e-14	76.3	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria,463M4@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_1449010_2	1123514.KB905901_gene6	1.86e-74	228.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,1S5X5@1236|Gammaproteobacteria,460X7@72273|Thiotrichales	72273|Thiotrichales	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
k59_1110176_1	637905.SVI_4190	2.92e-69	215.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,2Q8QA@267890|Shewanellaceae	1236|Gammaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	yrfG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
k59_320888_1	1237149.C900_00947	1.27e-19	87.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,47KWA@768503|Cytophagia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_150297_1	411154.GFO_0658	1.09e-26	103.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1HYAN@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_281520_1	326298.Suden_0549	2.71e-75	234.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2YND0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_281520_2	326298.Suden_0550	4.66e-15	73.9	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2YN13@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_1410528_1	1123514.KB905899_gene1637	7.49e-39	134.0	COG4706@1|root,COG4706@2|Bacteria,1RIH4@1224|Proteobacteria,1SFAZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1233681_1	504487.JCM19302_3408	2.44e-70	219.0	COG4733@1|root,COG4733@2|Bacteria,4NQRS@976|Bacteroidetes,1I3C0@117743|Flavobacteriia	2|Bacteria	S	cellulase activity	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	fn3
k59_1233681_2	1348583.ATLH01000023_gene550	8.04e-58	206.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia,1F8X1@104264|Cellulophaga	976|Bacteroidetes	G	SMART Glycosyl hydrolase, family 13, subfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_1014525_1	926562.Oweho_2553	2.1e-59	203.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1IG5U@117743|Flavobacteriia,2PBMV@246874|Cryomorphaceae	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_281584_1	745718.JADT01000013_gene1303	6.21e-08	53.1	28KJI@1|root,2ZA4I@2|Bacteria,4NFR7@976|Bacteroidetes,1I30H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_281584_2	1380600.AUYN01000007_gene3193	2.16e-101	297.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_1634408_1	580332.Slit_2321	5.75e-36	140.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WCD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9,Phosphonate-bd
k59_54760_1	746697.Aeqsu_1992	4.16e-111	335.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1634434_1	1123518.ARWI01000001_gene2133	1.13e-136	391.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,461XR@72273|Thiotrichales	72273|Thiotrichales	C	C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
k59_1014651_1	1168067.JAGP01000001_gene1523	3.89e-139	402.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria	1224|Proteobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_621216_1	317025.Tcr_1186	3.49e-52	184.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,45ZUZ@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_621234_1	1408473.JHXO01000001_gene1972	2.63e-200	588.0	COG2133@1|root,COG3391@1|root,COG3511@1|root,COG2133@2|Bacteria,COG3391@2|Bacteria,COG3511@2|Bacteria,4NER2@976|Bacteroidetes,2FQ0E@200643|Bacteroidia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_621234_2	616991.JPOO01000003_gene2345	3.28e-23	97.8	COG0160@1|root,COG0160@2|Bacteria,4NIHH@976|Bacteroidetes,1IG0C@117743|Flavobacteriia,23ICM@178469|Arenibacter	976|Bacteroidetes	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_54810_1	572480.Arnit_2475	4.65e-83	258.0	COG1344@1|root,COG1344@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1233884_1	1123518.ARWI01000001_gene1646	1.61e-36	131.0	COG4969@1|root,COG4969@2|Bacteria,1NI1H@1224|Proteobacteria,1SI05@1236|Gammaproteobacteria,4630D@72273|Thiotrichales	72273|Thiotrichales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_1233884_2	90814.KL370892_gene2169	1.98e-28	108.0	COG4968@1|root,COG4968@2|Bacteria,1QVB6@1224|Proteobacteria,1T2N7@1236|Gammaproteobacteria,461E5@72273|Thiotrichales	72273|Thiotrichales	NU	Type II secretion system (T2SS), protein I	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,T2SSI
k59_1233884_3	1123514.KB905903_gene416	3.6e-56	182.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
k59_621298_1	504487.JCM19302_4129	9.07e-193	546.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_1233933_1	572480.Arnit_2616	1.64e-170	518.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1014760_1	944547.ABLL_2147	7.74e-78	239.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,42KZB@68525|delta/epsilon subdivisions,2YN63@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_1014760_2	572480.Arnit_0528	4.96e-15	70.5	COG3610@1|root,COG3610@2|Bacteria,1RAWK@1224|Proteobacteria,42QRH@68525|delta/epsilon subdivisions,2YNRX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
k59_1014797_1	1041826.FCOL_05105	4.5e-68	214.0	COG2378@1|root,COG2378@2|Bacteria,4NY6E@976|Bacteroidetes,1I6QX@117743|Flavobacteriia	976|Bacteroidetes	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1410889_1	1537917.JU82_01025	3.23e-129	374.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2YMXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_1072841_1	1178825.ALIH01000003_gene2082	1.48e-117	350.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1HZ2W@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1072841_2	1123037.AUDE01000001_gene1898	1.75e-67	205.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_1072841_3	1223410.KN050846_gene1659	2.09e-96	295.0	28N2S@1|root,2ZB8K@2|Bacteria,4NY7A@976|Bacteroidetes,1I94F@117743|Flavobacteriia	976|Bacteroidetes	K	P63C domain	-	-	-	-	-	-	-	-	-	-	-	-	P63C
k59_1072841_4	1380600.AUYN01000006_gene696	1.83e-11	63.2	COG3677@1|root,COG3677@2|Bacteria,4NJC5@976|Bacteroidetes,1I0Y5@117743|Flavobacteriia	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_1072845_1	765914.ThisiDRAFT_2283	4.06e-88	273.0	COG3385@1|root,COG3385@2|Bacteria,1N963@1224|Proteobacteria,1SE1N@1236|Gammaproteobacteria,1WZEW@135613|Chromatiales	135613|Chromatiales	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_1072859_2	1236541.BALL01000016_gene2311	8.68e-37	135.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,2QB6T@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0099133,GO:1901265,GO:1901363	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	iECNA114_1301.ECNA114_0696,iECSF_1327.ECSF_0691,iUMNK88_1353.UMNK88_805	ABC_tran,TOBE
k59_281802_1	717773.Thicy_0755	3.1e-33	124.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1S11C@1236|Gammaproteobacteria,460N0@72273|Thiotrichales	72273|Thiotrichales	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_281802_2	1123514.KB905899_gene990	1.39e-52	184.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4601S@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1014933_1	745718.JADT01000003_gene2226	1.12e-84	257.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1072893_1	1121931.AUHG01000012_gene2545	2.93e-43	150.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1HWYY@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_1072893_2	411154.GFO_1634	3.05e-154	461.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_1072899_1	926559.JoomaDRAFT_2929	2.3e-14	68.6	COG2003@1|root,COG2003@2|Bacteria,4NRCM@976|Bacteroidetes,1I1KW@117743|Flavobacteriia	976|Bacteroidetes	L	DNA repair protein	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_54959_1	1237149.C900_03623	8.15e-32	119.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
k59_1634703_3	1249480.B649_07960	1.03e-53	181.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YMXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_281925_1	563040.Saut_1878	2.33e-144	417.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2YNCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1073012_1	1392489.JPOL01000002_gene720	2.23e-68	209.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2XJ5Y@283735|Leeuwenhoekiella	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_1073012_2	1178825.ALIH01000018_gene1163	4.66e-59	195.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1634773_1	1121931.AUHG01000012_gene2547	5.19e-126	386.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
k59_1073047_2	1123514.KB905899_gene1153	8.46e-65	206.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,4617N@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_1073047_3	90814.KL370891_gene1326	4.28e-26	106.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,460CG@72273|Thiotrichales	72273|Thiotrichales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k59_1634809_1	1123518.ARWI01000001_gene2080	1.95e-75	248.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,45ZUZ@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1634809_2	1123518.ARWI01000001_gene2075	1.11e-30	114.0	COG0500@1|root,COG2226@2|Bacteria,1MYW1@1224|Proteobacteria,1S707@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_1015150_1	411154.GFO_2961	1.74e-135	400.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_55122_1	929558.SMGD1_0299	3.65e-61	204.0	COG4942@1|root,COG4942@2|Bacteria,1QV6K@1224|Proteobacteria,42M9V@68525|delta/epsilon subdivisions,2YMS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_956899_1	944547.ABLL_2010	6.24e-97	288.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,42QNE@68525|delta/epsilon subdivisions,2YNCP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k59_956913_1	1121931.AUHG01000011_gene2054	1.09e-60	203.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_55174_1	156889.Mmc1_2065	9.3e-21	90.9	COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,2UEGK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Endonuclease I	-	-	3.1.21.1	ko:K01150	-	-	-	-	ko00000,ko01000	-	-	-	Endonuclease_1
k59_956997_1	1380600.AUYN01000003_gene244	9.78e-86	277.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_1015274_1	1565129.JSFF01000003_gene2215	2.44e-110	318.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,2Q9I9@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	lrp	GO:0000976,GO:0001067,GO:0001101,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009078,GO:0009080,GO:0009081,GO:0009082,GO:0009098,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016053,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046394,GO:0046395,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901698,GO:1901700,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k59_1015315_2	1172190.M947_07850	6.88e-44	159.0	COG1287@1|root,COG1287@2|Bacteria,1R481@1224|Proteobacteria,42MNZ@68525|delta/epsilon subdivisions,2YMU3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oligosaccharyl transferase, STT3 subunit	pglB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.99.18,2.4.99.19	ko:K07151,ko:K17251	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
k59_1015354_1	1123228.AUIH01000015_gene528	4.86e-98	292.0	COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,1RNFR@1236|Gammaproteobacteria,1XH35@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	ilvY	-	-	ko:K02521	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_957114_1	425104.Ssed_0069	3.58e-29	106.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,2QC2X@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k59_957114_2	319224.Sputcn32_3467	1.96e-60	188.0	COG1558@1|root,COG1558@2|Bacteria,1RJB8@1224|Proteobacteria,1S8B7@1236|Gammaproteobacteria,2QBPF@267890|Shewanellaceae	1236|Gammaproteobacteria	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1411527_1	377629.TERTU_3429	1.34e-22	96.7	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,2PMJ8@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_1411527_2	290398.Csal_1854	1.54e-35	129.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S82S@1236|Gammaproteobacteria,1XREC@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_282381_1	1121896.JMLU01000002_gene338	2.45e-203	593.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2NSTD@237|Flavobacterium	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1234651_1	760154.Sulba_0098	1.76e-101	314.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2YNNE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_1015513_1	318167.Sfri_2412	9.35e-114	333.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,2QAE8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k59_1234680_1	1239962.C943_01654	5.18e-70	234.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
k59_1234684_1	1353528.DT23_18185	1.91e-105	327.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2XM4U@285107|Thioclava	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_957305_1	411154.GFO_3535	4.71e-124	382.0	COG1361@1|root,COG1361@2|Bacteria,4PM78@976|Bacteroidetes,1IJZ7@117743|Flavobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
k59_1635240_1	1336233.JAEH01000015_gene3277	1.13e-85	265.0	28MJ4@1|root,2ZAVQ@2|Bacteria,1R62K@1224|Proteobacteria,1RNQC@1236|Gammaproteobacteria,2QADS@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	VP2126	-	-	-	-	-	-	-	-	-	-	-	-
k59_55529_1	317025.Tcr_1153	3.16e-32	124.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,45ZQ1@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_55529_2	1168067.JAGP01000001_gene1374	3.58e-115	340.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,46209@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K22067	-	-	-	-	ko00000,ko02022	-	-	-	NMT1_2
k59_55556_1	563040.Saut_1566	8.53e-75	233.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2YME1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	heptosyltransferase ii	waaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_1015648_1	1178825.ALIH01000004_gene2842	1.21e-125	362.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1HWN1@117743|Flavobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k59_1015648_2	1123037.AUDE01000024_gene1597	5.66e-72	219.0	COG2050@1|root,COG2050@2|Bacteria,4NNXM@976|Bacteroidetes,1I1ZV@117743|Flavobacteriia	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
k59_1015648_3	1380600.AUYN01000009_gene1500	7.39e-78	234.0	COG3296@1|root,COG3296@2|Bacteria,4NUD1@976|Bacteroidetes,1I4G4@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
k59_1411805_1	1042376.AFPK01000062_gene1318	2.45e-249	703.0	COG1653@1|root,COG1653@2|Bacteria,4NG6U@976|Bacteroidetes	976|Bacteroidetes	G	Pfam Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_1411805_2	1280676.AUJO01000001_gene2634	2.98e-16	81.6	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,4BY9Z@830|Butyrivibrio	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
k59_1082370_1	694429.Pyrfu_1382	2.77e-20	89.7	COG0007@1|root,arCOG00644@2157|Archaea,2XQ85@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cobA	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k59_1082370_2	1168067.JAGP01000001_gene1363	6.36e-126	370.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,460P7@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Glycosyl transferase, family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_1421930_2	1380600.AUYN01000009_gene1256	1.72e-87	275.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1HZII@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
k59_292507_1	572480.Arnit_0160	4.95e-16	76.6	COG0642@1|root,COG0642@2|Bacteria,1QZF0@1224|Proteobacteria,43CI9@68525|delta/epsilon subdivisions,2YTCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_292507_2	1122201.AUAZ01000005_gene625	1.5e-54	191.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,464J4@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_688493_1	929558.SMGD1_1509	7.49e-46	152.0	2AIVF@1|root,319NT@2|Bacteria,1Q3D4@1224|Proteobacteria,42X4I@68525|delta/epsilon subdivisions,2YQUS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Flagellar FliJ protein	-	-	-	-	-	-	-	-	-	-	-	-	FliJ
k59_631511_1	1254432.SCE1572_39385	3.7e-15	72.8	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria,2YXMZ@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_631511_2	671143.DAMO_0041	4.11e-36	134.0	COG0577@1|root,COG0577@2|Bacteria,2NQPT@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1364736_1	1194165.CAJF01000039_gene1723	0.000962	42.4	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4FKWI@85023|Microbacteriaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1364736_2	1232683.ADIMK_1202	1.64e-07	52.8	COG4177@1|root,COG4177@2|Bacteria,1QF6I@1224|Proteobacteria,1SMBR@1236|Gammaproteobacteria,46A6X@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_969294_1	1123228.AUIH01000012_gene16	8.26e-71	234.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XHCB@135619|Oceanospirillales	135619|Oceanospirillales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_1534537_1	1121912.AUHD01000005_gene1625	1.78e-186	526.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_1139171_1	1123514.KB905899_gene1688	7.17e-116	345.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,46016@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k59_1139171_2	1123514.KB905899_gene1687	7.32e-30	112.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,460TZ@72273|Thiotrichales	72273|Thiotrichales	G	Phosphoheptose isomerase	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_856861_1	1121931.AUHG01000011_gene2188	9.35e-114	349.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_179999_1	1178825.ALIH01000007_gene1690	1.92e-70	226.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_348405_1	572480.Arnit_2980	3.79e-17	80.1	COG0464@1|root,COG0464@2|Bacteria,1N4ZI@1224|Proteobacteria,42NGJ@68525|delta/epsilon subdivisions,2YMAX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATPase (AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_1648383_2	1121004.ATVC01000042_gene955	4.87e-09	59.3	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,2KU2G@206351|Neisseriales	206351|Neisseriales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1534558_1	90814.KL370892_gene2337	1.01e-165	477.0	COG0845@1|root,COG0845@2|Bacteria,1MWZ9@1224|Proteobacteria,1RM91@1236|Gammaproteobacteria,4621R@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1534558_2	765914.ThisiDRAFT_2460	3.64e-51	182.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW08@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_856888_1	1121931.AUHG01000012_gene2675	5.97e-76	229.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1HX4U@117743|Flavobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_856888_2	411154.GFO_1491	2.4e-34	119.0	2CJFR@1|root,32RQT@2|Bacteria,4NSHX@976|Bacteroidetes,1I4E2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1193511_1	1347342.BN863_3120	5.37e-208	603.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HY96@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_1193511_2	1250005.PHEL85_3061	5.86e-107	319.0	28J3Q@1|root,2Z8ZW@2|Bacteria,4NGJW@976|Bacteroidetes,1HZI5@117743|Flavobacteriia,3VV3M@52959|Polaribacter	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
k59_1193511_3	1123037.AUDE01000012_gene175	1.15e-109	325.0	28J3Q@1|root,2ZBKS@2|Bacteria,4NMY8@976|Bacteroidetes,1I1AM@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
k59_1193511_4	641526.ADIWIN_3221	3.38e-80	253.0	COG0642@1|root,COG2205@2|Bacteria,4NISE@976|Bacteroidetes,1I00Q@117743|Flavobacteriia	976|Bacteroidetes	T	Signal Transduction Histidine Kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1422007_1	563040.Saut_1908	3.61e-46	151.0	COG0792@1|root,COG0792@2|Bacteria,1Q27V@1224|Proteobacteria,42V4E@68525|delta/epsilon subdivisions,2YQJM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_1422007_2	1150621.SMUL_0079	1.87e-30	119.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2YMS1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1761473_1	1046627.BZARG_2137	6.29e-105	309.0	COG1577@1|root,COG1577@2|Bacteria,4NDYJ@976|Bacteroidetes,1HX9R@117743|Flavobacteriia	976|Bacteroidetes	I	mevalonate kinase	mvaK	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1761473_2	1137281.D778_02756	7.93e-59	189.0	COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,1HX57@117743|Flavobacteriia	976|Bacteroidetes	H	Prenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_744080_1	1380600.AUYN01000009_gene2061	5.23e-51	178.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_744080_2	1137281.D778_00130	4.8e-33	124.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1704725_1	504487.JCM19302_1732	4.07e-28	107.0	COG0607@1|root,COG0607@2|Bacteria,4NPZQ@976|Bacteroidetes,1I2PS@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1704725_2	504487.JCM19302_1733	2.05e-105	308.0	COG2391@1|root,COG2391@2|Bacteria,4NMK0@976|Bacteroidetes,1I1SD@117743|Flavobacteriia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_1704725_3	1250005.PHEL85_2144	6.09e-111	320.0	COG2391@1|root,COG2391@2|Bacteria,4NGS1@976|Bacteroidetes,1I0G8@117743|Flavobacteriia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_1704725_4	1250005.PHEL85_2143	4.63e-193	540.0	COG3301@1|root,COG3301@2|Bacteria,4NITJ@976|Bacteroidetes,1I0XA@117743|Flavobacteriia	976|Bacteroidetes	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_1704725_5	504487.JCM19302_1737	2.42e-131	372.0	COG0437@1|root,COG0437@2|Bacteria,4NK7Y@976|Bacteroidetes,1I0UN@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
k59_1704725_6	504487.JCM19302_1738	3.44e-68	217.0	COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes,1I01Y@117743|Flavobacteriia	976|Bacteroidetes	C	Molybdopterin oxidoreductase	-	-	1.7.2.3	ko:K07812	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.4	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1478567_1	504487.JCM19302_771	7.75e-84	265.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1I02Y@117743|Flavobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
k59_744085_1	1288963.ADIS_1538	6.34e-10	58.5	COG3772@1|root,COG3772@2|Bacteria,4NVJ5@976|Bacteroidetes,47STG@768503|Cytophagia	976|Bacteroidetes	S	Phage lysozyme	-	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	Phage_lysozyme
k59_1704730_1	1190606.AJYG01000057_gene3878	1.56e-111	330.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1XVNR@135623|Vibrionales	135623|Vibrionales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_292614_1	90814.KL370892_gene2183	3.98e-36	132.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,46017@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_292614_2	1123518.ARWI01000001_gene1507	3.45e-65	202.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,4619T@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_292614_3	1168067.JAGP01000001_gene2083	3.05e-11	62.8	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,45ZNS@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_462499_1	1565129.JSFF01000013_gene241	8.16e-18	80.1	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,2QADC@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Permease MlaE	mlaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_462499_2	1565129.JSFF01000013_gene240	3.65e-96	281.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,2QBMR@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_801292_1	1298593.TOL_2111	2.22e-106	323.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1XHYU@135619|Oceanospirillales	135619|Oceanospirillales	G	Alpha amylase, catalytic domain	-	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_688602_1	563040.Saut_0319	7.11e-118	372.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2YMP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1193533_1	1250278.JQNQ01000001_gene2495	7.25e-17	80.5	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1HX2N@117743|Flavobacteriia	976|Bacteroidetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_1193533_2	411154.GFO_2324	4.74e-81	245.0	COG1416@1|root,COG1416@2|Bacteria,4NQQE@976|Bacteroidetes,1I35I@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_1648434_1	944547.ABLL_2639	2.13e-96	295.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_1252355_1	1121887.AUDK01000004_gene377	5.25e-53	170.0	COG2346@1|root,COG2346@2|Bacteria,4NSU1@976|Bacteroidetes,1I4A6@117743|Flavobacteriia,2NZ6C@237|Flavobacterium	976|Bacteroidetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1252355_2	411154.GFO_0652	2.19e-36	135.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_1422059_1	563040.Saut_0765	1.06e-154	441.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2YMGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_856953_1	90814.KL370892_gene2070	6.83e-66	212.0	COG1493@1|root,COG1493@2|Bacteria,1R0JS@1224|Proteobacteria,1T2N5@1236|Gammaproteobacteria,46295@72273|Thiotrichales	72273|Thiotrichales	T	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_66875_1	1380600.AUYN01000009_gene990	2.53e-140	416.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
k59_1252367_1	1249997.JHZW01000003_gene3308	2.08e-116	346.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia,2PGUY@252356|Maribacter	976|Bacteroidetes	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
k59_575112_1	1121931.AUHG01000011_gene2407	0.00016	43.5	2985A@1|root,2ZVB7@2|Bacteria,4NNTB@976|Bacteroidetes,1I0QR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4494
k59_631653_1	1056512.D515_02744	4.94e-07	49.3	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S46K@1236|Gammaproteobacteria,1XWWR@135623|Vibrionales	135623|Vibrionales	C	Prokaryotic cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
k59_631653_2	1123518.ARWI01000001_gene694	1.39e-126	368.0	2DBB6@1|root,2Z85M@2|Bacteria,1QMDX@1224|Proteobacteria,1RZPX@1236|Gammaproteobacteria,461IY@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_631653_3	55601.VANGNB10_cI1520	7.04e-10	58.5	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1XU3W@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
k59_801339_1	1123518.ARWI01000001_gene639	4.63e-69	216.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,4612A@72273|Thiotrichales	72273|Thiotrichales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_1534641_1	1123514.KB905899_gene1313	3.21e-98	310.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1534641_2	317025.Tcr_1118	4.97e-21	91.3	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,45ZPK@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1704787_2	1380600.AUYN01000003_gene119	9.27e-168	497.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,1HXZS@117743|Flavobacteriia	976|Bacteroidetes	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_518258_1	90813.JQMT01000001_gene309	2.36e-66	212.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,461KC@72273|Thiotrichales	72273|Thiotrichales	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_1648492_1	317025.Tcr_1965	9.47e-131	382.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_1139303_1	391587.KAOT1_10336	7.07e-33	121.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
k59_1139303_2	869213.JCM21142_432	1.57e-56	186.0	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes,47VCU@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1193587_1	929558.SMGD1_1520	4.1e-86	278.0	COG2887@1|root,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_913694_2	944547.ABLL_1765	1.41e-17	89.4	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,SBP_bac_3
k59_1252414_1	749222.Nitsa_1297	2.73e-51	174.0	COG3677@1|root,COG3677@2|Bacteria,1RBA7@1224|Proteobacteria,4304X@68525|delta/epsilon subdivisions,2YRUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_292721_1	504487.JCM19302_3392	7.63e-154	452.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1HX5N@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208,ko:K21575	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_462608_1	1565129.JSFF01000028_gene717	3.86e-134	401.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,2Q9ZW@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iSDY_1059.SDY_2428	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_1648505_1	1250232.JQNJ01000001_gene2195	3.6e-144	411.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes,1HYCI@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k59_1648505_2	1380600.AUYN01000009_gene1336	9.09e-161	458.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1HYAM@117743|Flavobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
k59_576904_1	717773.Thicy_0387	8.5e-93	297.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,4600B@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k59_1366586_2	326298.Suden_1446	6.03e-16	78.2	COG0249@1|root,COG1403@1|root,COG0249@2|Bacteria,COG1403@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2YN6Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA mismatch repair MutS family	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
k59_1084197_1	1353276.JADR01000001_gene9	2.71e-58	191.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HZNF@117743|Flavobacteriia	976|Bacteroidetes	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DUF3887,Hydrolase_4
k59_1084197_2	504487.JCM19302_3078	3.26e-30	113.0	28V2E@1|root,2ZH5W@2|Bacteria,4NH6Z@976|Bacteroidetes,1I04G@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
k59_858769_1	946483.Cenrod_2578	1.86e-39	155.0	COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2203@1|root,COG3614@1|root,COG3829@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG3614@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
k59_633500_1	504487.JCM19302_759	2.24e-142	421.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_1254070_1	411154.GFO_1092	8.42e-102	306.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
k59_238432_1	713586.KB900536_gene2402	2.07e-166	497.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_238432_2	177439.DP2435	7.93e-90	268.0	COG1814@1|root,COG1814@2|Bacteria,1RBQN@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1706650_1	1380600.AUYN01000003_gene87	3.75e-77	248.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HY5T@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1140910_1	945713.IALB_2754	7.02e-75	239.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
k59_1499865_1	1380600.AUYN01000009_gene1628	1.22e-12	67.8	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1HXNC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_1499865_2	1380600.AUYN01000009_gene1628	5.39e-145	432.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1HXNC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_1499865_3	1137281.D778_00403	5.64e-99	289.0	COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,1I1YB@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1499865_4	1380600.AUYN01000009_gene1630	9.3e-67	207.0	COG1413@1|root,COG1413@2|Bacteria,4NUQJ@976|Bacteroidetes,1I52N@117743|Flavobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1499865_5	1380600.AUYN01000009_gene1631	2.18e-43	146.0	28P9K@1|root,2ZC31@2|Bacteria,4NPW6@976|Bacteroidetes,1I1KA@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
k59_1102707_1	391603.FBALC1_02487	3.62e-46	159.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1HWNT@117743|Flavobacteriia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
k59_1725382_1	1117647.M5M_17235	3.16e-34	125.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,1J8RF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
k59_1725382_2	326298.Suden_1950	9.69e-55	179.0	COG0697@1|root,COG0697@2|Bacteria,1PIFB@1224|Proteobacteria,42QAN@68525|delta/epsilon subdivisions,2YNGI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	integral membrane protein (DUF6 domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_87538_1	1137281.D778_02324	2.52e-242	687.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_368599_1	1057002.KB905370_gene4162	3.45e-05	46.6	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2TVMK@28211|Alphaproteobacteria,4BJ5P@82115|Rhizobiaceae	28211|Alphaproteobacteria	KP	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
k59_368599_2	1123514.KB905899_gene1775	3.03e-30	117.0	COG2223@1|root,COG2223@2|Bacteria,1QVX0@1224|Proteobacteria,1T2MB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_426050_1	1392490.JHZX01000001_gene2368	8.66e-42	160.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
k59_1782771_1	563040.Saut_0267	4.06e-158	457.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_1441804_1	411154.GFO_3097	4.75e-103	317.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1HX3E@117743|Flavobacteriia	976|Bacteroidetes	O	peptidase family M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_1499901_1	204536.SULAZ_0036	0.000438	44.3	COG2703@1|root,COG2703@2|Bacteria,2G48F@200783|Aquificae	200783|Aquificae	P	TIGRFAM hemerythrin-like metal-binding protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_313309_2	714943.Mucpa_7145	1.11e-43	158.0	COG3637@1|root,COG3637@2|Bacteria,4NJV9@976|Bacteroidetes,1J19A@117747|Sphingobacteriia	976|Bacteroidetes	M	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1782807_1	929558.SMGD1_2810	3.63e-103	304.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,42WVD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_200712_1	1123518.ARWI01000001_gene2018	6.88e-52	166.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k59_200712_2	1123518.ARWI01000001_gene2019	1.83e-77	236.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,460Q4@72273|Thiotrichales	72273|Thiotrichales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_142921_1	1178825.ALIH01000003_gene2173	1.69e-113	357.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1499963_1	411154.GFO_2646	2.08e-68	222.0	COG2271@1|root,COG2271@2|Bacteria,4NK2M@976|Bacteroidetes,1I107@117743|Flavobacteriia	976|Bacteroidetes	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1102791_1	1123518.ARWI01000001_gene127	4.06e-47	157.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1102791_2	574966.KB898652_gene1788	5.58e-51	166.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1XJD0@135619|Oceanospirillales	135619|Oceanospirillales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_822744_1	1121931.AUHG01000010_gene248	2.23e-45	154.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_822744_2	1121931.AUHG01000010_gene249	5.32e-172	492.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1047088_1	572480.Arnit_2440	3.3e-122	361.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2YMN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1613917_1	985867.AEWF01000002_gene1399	6.64e-13	70.9	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria,47GQB@766|Rickettsiales	766|Rickettsiales	I	Steryl acetyl hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
k59_1613917_2	1123228.AUIH01000010_gene4004	6.77e-30	111.0	COG3751@1|root,COG3751@2|Bacteria,1NAUK@1224|Proteobacteria,1S2G4@1236|Gammaproteobacteria,1XJF9@135619|Oceanospirillales	135619|Oceanospirillales	O	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
k59_652446_1	1123518.ARWI01000001_gene1434	1.91e-179	504.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,460JD@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_652446_2	1168067.JAGP01000001_gene2197	4.83e-99	296.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,460P3@72273|Thiotrichales	72273|Thiotrichales	M	lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_652446_3	326298.Suden_1784	1.5e-31	121.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_200738_1	90814.KL370891_gene1224	4.2e-228	645.0	COG0469@1|root,COG0469@2|Bacteria,1NNNX@1224|Proteobacteria,1RYF5@1236|Gammaproteobacteria,461PZ@72273|Thiotrichales	72273|Thiotrichales	G	Pyruvate kinase, barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PK
k59_200738_2	326297.Sama_2494	7.56e-62	198.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,2QB8E@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM cytochrome B561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_1500002_1	1380600.AUYN01000009_gene2038	1.23e-93	291.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_652462_1	411154.GFO_0063	2.04e-112	329.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia	976|Bacteroidetes	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_257885_1	1173024.KI912149_gene5528	2.06e-20	95.9	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_822815_1	411154.GFO_1471	1.58e-123	360.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
k59_652476_1	1353528.DT23_12665	1.05e-108	317.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2XM7K@285107|Thioclava	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_483279_2	1122139.KB907872_gene2291	1.05e-25	107.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1441923_1	1380600.AUYN01000003_gene12	1.24e-09	58.2	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1HXB7@117743|Flavobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_142996_1	326298.Suden_1967	2.8e-99	317.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
k59_1782905_1	458817.Shal_3213	9.61e-24	96.3	COG3017@1|root,COG3017@2|Bacteria,1QB0U@1224|Proteobacteria,1T6HZ@1236|Gammaproteobacteria,2QBBQ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
k59_764313_1	572480.Arnit_1253	2.18e-170	491.0	COG2956@1|root,COG2956@2|Bacteria,1PDTB@1224|Proteobacteria,42PNY@68525|delta/epsilon subdivisions,2YN3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ciaB	-	-	-	-	-	-	-	-	-	-	-	-
k59_764313_2	572480.Arnit_1247	2.12e-94	289.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_1441938_1	411154.GFO_2997	5.47e-87	273.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1HXCC@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_933373_1	1123518.ARWI01000001_gene747	1.18e-89	270.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,462EM@72273|Thiotrichales	72273|Thiotrichales	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_933373_2	1123514.KB905899_gene1549	1.35e-45	148.0	2CT64@1|root,32SSN@2|Bacteria,1N7H4@1224|Proteobacteria,1SEH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
k59_933373_3	500632.CLONEX_03829	1.92e-79	246.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_933373_4	1226994.AMZB01000084_gene357	8.86e-14	69.3	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1YDWD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	JM	Nucleotidyl transferase	-	GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_143016_1	929558.SMGD1_1694	1.99e-80	253.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2YMP5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_143016_2	1172190.M947_04205	2.24e-05	45.4	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2YNBN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1159550_2	1121931.AUHG01000012_gene2892	1.43e-89	263.0	COG5592@1|root,COG5592@2|Bacteria,4NNME@976|Bacteroidetes,1I20D@117743|Flavobacteriia	976|Bacteroidetes	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_1159550_3	1121931.AUHG01000012_gene2893	1.12e-27	109.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_483306_1	709032.Sulku_1031	4.66e-46	164.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42Q9B@68525|delta/epsilon subdivisions,2YNKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_1613984_1	1121931.AUHG01000010_gene290	2.79e-221	620.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1HXAH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_933384_1	1121931.AUHG01000010_gene549	5.95e-38	135.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the FBPase class 1 family	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_933384_2	1121931.AUHG01000010_gene550	5.4e-89	262.0	COG4103@1|root,COG4103@2|Bacteria,4NNTQ@976|Bacteroidetes,1I292@117743|Flavobacteriia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_933384_3	1121931.AUHG01000010_gene551	5.24e-46	156.0	COG1236@1|root,COG1236@2|Bacteria,4NFN7@976|Bacteroidetes,1HZJP@117743|Flavobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
k59_1613998_1	945713.IALB_0283	7.41e-123	380.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
k59_31753_1	641526.ADIWIN_3405	1.21e-21	93.2	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_31753_2	1137281.D778_01450	1.96e-256	714.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1HWTB@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_597572_1	572480.Arnit_0378	4.68e-47	162.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,42MQ6@68525|delta/epsilon subdivisions,2YNPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_597572_2	572480.Arnit_0379	1.5e-101	307.0	COG1233@1|root,COG1233@2|Bacteria,1P0N4@1224|Proteobacteria,42NRZ@68525|delta/epsilon subdivisions,2YMGH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
k59_316316_1	1392490.JHZX01000001_gene2989	1.13e-73	223.0	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes,1I21F@117743|Flavobacteriia	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_316316_2	1178825.ALIH01000010_gene389	9.08e-64	197.0	2AFZR@1|root,3163Q@2|Bacteria,4NQFG@976|Bacteroidetes,1I3HJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_316316_3	946077.W5A_03279	2.98e-63	201.0	COG0664@1|root,COG0664@2|Bacteria,4NQ1A@976|Bacteroidetes,1I2DV@117743|Flavobacteriia	976|Bacteroidetes	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_371488_2	929558.SMGD1_0821	2.12e-187	532.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2YMI1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1785513_1	1121931.AUHG01000010_gene787	8.01e-129	369.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,1HWPP@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
k59_1785513_2	865937.Gilli_2633	0.000616	41.2	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1HWYJ@117743|Flavobacteriia,2P5WN@244698|Gillisia	976|Bacteroidetes	J	Elongation factor TS	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_1672008_1	425104.Ssed_2342	5.15e-55	194.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2Q9AA@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Outer membrane adhesin like proteiin	rtxA	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,Calx-beta,He_PIG,HemolysinCabind,VWA,VWA_2
k59_714121_1	1121931.AUHG01000011_gene2318	2.09e-138	396.0	COG0668@1|root,COG0668@2|Bacteria,4PKII@976|Bacteroidetes,1IJA3@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_1616816_1	1268622.AVS7_01622	4.29e-49	170.0	COG4222@1|root,COG4222@2|Bacteria,1MVDD@1224|Proteobacteria,2VPY0@28216|Betaproteobacteria,4ADB3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_90512_1	411154.GFO_3241	4e-171	498.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_31801_1	1110502.TMO_1965	5.32e-68	224.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2JQ1V@204441|Rhodospirillales	204441|Rhodospirillales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_371547_1	1123517.JOMR01000001_gene1325	1.54e-95	291.0	2DMHZ@1|root,32RNI@2|Bacteria	2|Bacteria	S	4-alpha-L-fucosyltransferase glycosyl transferase group 56	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_56
k59_371547_2	1123517.JOMR01000001_gene1324	2.7e-48	167.0	COG2244@1|root,COG2244@2|Bacteria,1R5PY@1224|Proteobacteria,1SZZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_1557483_1	1565129.JSFF01000017_gene2947	1.19e-146	432.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,1T2P0@1236|Gammaproteobacteria,2Q9EC@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_429146_1	1340493.JNIF01000003_gene4230	3.84e-09	55.1	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_429146_2	983544.Lacal_2773	3.86e-95	283.0	COG0664@1|root,COG0664@2|Bacteria,4NJRX@976|Bacteroidetes,1IIWQ@117743|Flavobacteriia	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_429146_3	1178825.ALIH01000005_gene173	1.63e-56	180.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I30V@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
k59_1728437_1	1123503.KB908056_gene1755	6.37e-85	254.0	2CI52@1|root,2ZC5H@2|Bacteria,1R9WI@1224|Proteobacteria,2V5NR@28211|Alphaproteobacteria,2KJP6@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_714203_1	864051.BurJ1DRAFT_0167	3.74e-107	318.0	COG2770@1|root,COG2770@2|Bacteria,1QZYS@1224|Proteobacteria,2VJTC@28216|Betaproteobacteria,1KJFF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP
k59_145860_1	1123514.KB905899_gene1017	1.29e-37	137.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,460YG@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_145860_2	90814.KL370891_gene1059	3.3e-111	325.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,460KG@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_1616890_2	1178825.ALIH01000010_gene370	6.91e-99	314.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HX6K@117743|Flavobacteriia	976|Bacteroidetes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
k59_665514_2	62928.azo2794	1.22e-59	196.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,2KUV1@206389|Rhodocyclales	206389|Rhodocyclales	S	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1567330_1	216432.CA2559_02940	9.07e-33	125.0	COG0438@1|root,COG0438@2|Bacteria,4NGSA@976|Bacteroidetes,1I0MH@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_41281_2	391603.FBALC1_13262	5.47e-116	336.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1HXNW@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_41281_3	504487.JCM19302_3103	6.74e-36	123.0	COG4281@1|root,COG4281@2|Bacteria,4NSPP@976|Bacteroidetes,1I42A@117743|Flavobacteriia	976|Bacteroidetes	I	Acyl CoA binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
k59_1058270_1	411154.GFO_3166	5.39e-70	226.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1HXFR@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_1058270_2	1121931.AUHG01000010_gene137	9.36e-112	330.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1HY2X@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1115722_1	504487.JCM19302_759	8.69e-192	550.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_213542_1	321846.PS417_08165	8.91e-150	428.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Polysaccharide biosynthesis protein	fnlA	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
k59_1513127_1	469595.CSAG_04062	6.1e-20	94.4	28KC1@1|root,2Z9Z1@2|Bacteria,1MW96@1224|Proteobacteria,1RYPT@1236|Gammaproteobacteria,3WVA5@544|Citrobacter	1236|Gammaproteobacteria	S	Type-1V conjugative transfer system mating pair stabilisation	traN	-	-	ko:K12058	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraN
k59_1624938_1	1123228.AUIH01000006_gene2210	3.86e-06	47.4	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XJI5@135619|Oceanospirillales	135619|Oceanospirillales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_1624938_2	1123228.AUIH01000006_gene2211	1.51e-71	222.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,1XJ7A@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_326385_1	504487.JCM19302_3522	1.18e-95	289.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia	976|Bacteroidetes	S	Flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_549922_1	562742.F4YXT9_9CAUD	2.33e-92	289.0	4QG8X@10239|Viruses,4QVDN@35237|dsDNA viruses  no RNA stage,4QSBT@28883|Caudovirales,4QM55@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_549922_4	279383.Q5DN23_9CAUD	7.67e-71	240.0	4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses  no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae	10699|Siphoviridae	S	peptidoglycan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1058357_1	929558.SMGD1_0567	8.5e-93	277.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,42RK1@68525|delta/epsilon subdivisions,2YPBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_268981_1	1165841.SULAR_02478	3.98e-31	125.0	COG5276@1|root,COG5276@2|Bacteria,1NTT8@1224|Proteobacteria,42ZD4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
k59_1454266_1	414684.RC1_3949	2.5e-46	156.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,2JQTW@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1513191_2	1123518.ARWI01000001_gene1042	5.63e-100	291.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,460JG@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_1513191_3	317025.Tcr_0292	3.28e-116	351.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,46061@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_326406_1	411154.GFO_2677	6.46e-122	350.0	COG3663@1|root,COG3663@2|Bacteria,4NEZ4@976|Bacteroidetes,1HY0W@117743|Flavobacteriia	976|Bacteroidetes	L	G T U mismatch-specific DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_495701_1	326298.Suden_1850	8.25e-44	148.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_495701_2	326298.Suden_1849	1.21e-51	172.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2YNC5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_495706_1	929558.SMGD1_0746	3.78e-92	286.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2YMF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_495715_1	1249480.B649_11095	4.89e-97	292.0	COG1502@1|root,COG1502@2|Bacteria,1R51A@1224|Proteobacteria,42PGS@68525|delta/epsilon subdivisions,2YNQ6@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
k59_1513223_1	929558.SMGD1_2587	5.74e-41	145.0	2C76X@1|root,2ZM1W@2|Bacteria,1P5JD@1224|Proteobacteria,42P9T@68525|delta/epsilon subdivisions,2YMRC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1513223_2	563040.Saut_1059	4.95e-61	200.0	COG3190@1|root,COG3190@2|Bacteria,1Q1CX@1224|Proteobacteria,42PAU@68525|delta/epsilon subdivisions,2YP0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1285837_1	339671.Asuc_1378	1.44e-20	95.1	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1Y71U@135625|Pasteurellales	135625|Pasteurellales	H	Molybdopterin	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_1172543_1	1484460.JSWG01000006_gene2845	1.02e-88	282.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_777010_1	1380600.AUYN01000009_gene2037	1.54e-98	308.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,1HXNB@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
k59_890247_1	545264.KB898745_gene1288	4.91e-24	103.0	COG2199@1|root,COG3706@2|Bacteria,1QYKR@1224|Proteobacteria,1T3X5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_1513239_1	1355368.JART01000024_gene1573	6.17e-93	295.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	DUF900,Sel1,TPR_8
k59_998743_1	458817.Shal_0844	3.36e-110	335.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,2QAEP@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1285842_1	1121931.AUHG01000020_gene3174	2.84e-25	102.0	2DBKE@1|root,2Z9SW@2|Bacteria,4NRWN@976|Bacteroidetes,1I012@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
k59_1285842_2	1178825.ALIH01000006_gene1420	4.15e-135	384.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1HX8T@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_1285842_3	1380600.AUYN01000010_gene901	1.04e-155	442.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1HY7B@117743|Flavobacteriia	976|Bacteroidetes	N	flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1285842_4	1380600.AUYN01000010_gene902	2.14e-180	508.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1HXBB@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
k59_1285842_5	1380600.AUYN01000010_gene903	4.65e-81	242.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia	976|Bacteroidetes	V	Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
k59_213677_1	929558.SMGD1_0812	2.27e-236	672.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2YMNT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1115875_1	1380600.AUYN01000009_gene1194	7.56e-145	416.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1HX9B@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_326476_1	945713.IALB_1992	2.28e-88	268.0	COG0331@1|root,COG0331@2|Bacteria	2|Bacteria	I	[acyl-carrier-protein] S-malonyltransferase activity	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
k59_606305_1	1191523.MROS_0441	2.21e-54	184.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_777064_1	1121931.AUHG01000016_gene1055	2.14e-158	474.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_381453_2	1121904.ARBP01000044_gene2080	6.6e-24	103.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,47TZD@768503|Cytophagia	976|Bacteroidetes	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1058475_1	1499683.CCFF01000015_gene3313	7.57e-58	196.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,36EFK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_777072_1	1121931.AUHG01000010_gene730	3.37e-57	185.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_724341_2	1005994.GTGU_04133	4.94e-22	99.0	COG5301@1|root,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF3751,Phage_fiber_2
k59_1567579_1	90814.KL370891_gene529	9.89e-160	459.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_100950_1	768066.HELO_2644	4.83e-17	79.7	28TC4@1|root,2ZFKJ@2|Bacteria,1P81C@1224|Proteobacteria,1SUYI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100950_2	1215092.PA6_009_00300	1.81e-57	186.0	28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein-protein 5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213757_1	1380600.AUYN01000001_gene2670	1.54e-63	221.0	COG1345@1|root,COG1361@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
k59_1454390_1	132113.XP_003490692.1	8.45e-05	47.0	COG1132@1|root,KOG0055@2759|Eukaryota,38E88@33154|Opisthokonta,3B958@33208|Metazoa,3CVKH@33213|Bilateria,41WNN@6656|Arthropoda,3SIMD@50557|Insecta,46JJR@7399|Hymenoptera	33208|Metazoa	Q	Multidrug resistance protein homolog 49-like	pgp-2	GO:0000003,GO:0001666,GO:0003008,GO:0003014,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0005911,GO:0005918,GO:0005919,GO:0006810,GO:0006855,GO:0006928,GO:0006950,GO:0006996,GO:0007275,GO:0007276,GO:0007399,GO:0008150,GO:0008354,GO:0008559,GO:0009628,GO:0009636,GO:0009987,GO:0010001,GO:0010876,GO:0015238,GO:0015399,GO:0015405,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017085,GO:0017111,GO:0019915,GO:0019953,GO:0021782,GO:0022008,GO:0022412,GO:0022414,GO:0022804,GO:0022857,GO:0030054,GO:0030154,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033036,GO:0036293,GO:0040011,GO:0042063,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043190,GO:0043226,GO:0043227,GO:0043229,GO:0043296,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044840,GO:0044841,GO:0046903,GO:0048468,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051674,GO:0051704,GO:0055085,GO:0060856,GO:0060857,GO:0065007,GO:0065008,GO:0070160,GO:0070482,GO:0071840,GO:0071944,GO:0097254,GO:0097708,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.44	ko:K05658	ko02010,ko04976,ko05206,ko05226,map02010,map04976,map05206,map05226	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04090,ko04147	3.A.1.201	-	-	ABC_membrane,ABC_tran
k59_552826_1	411154.GFO_3117	3.14e-97	304.0	COG2234@1|root,COG2234@2|Bacteria,4PKJJ@976|Bacteroidetes,1HX9M@117743|Flavobacteriia	976|Bacteroidetes	G	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_836561_1	1123228.AUIH01000003_gene855	2.79e-75	236.0	COG1876@1|root,COG1876@2|Bacteria,1RB64@1224|Proteobacteria,1RRSM@1236|Gammaproteobacteria,1XNHR@135619|Oceanospirillales	135619|Oceanospirillales	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
k59_43886_1	1249975.JQLP01000001_gene3492	5.31e-22	90.1	2DPP3@1|root,332UB@2|Bacteria,4PMSJ@976|Bacteroidetes,1I5CZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
k59_43886_2	1123234.AUKI01000019_gene495	5.86e-21	91.3	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
k59_1061256_1	929558.SMGD1_1174	4.29e-91	275.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2YN3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0663	Chorismate_synt
k59_1061256_2	1165841.SULAR_09889	2.27e-49	164.0	2AINN@1|root,31954@2|Bacteria,1NDHA@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
k59_552834_1	317025.Tcr_0040	4.3e-91	268.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,1S40B@1236|Gammaproteobacteria,460XE@72273|Thiotrichales	72273|Thiotrichales	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
k59_780169_1	1123518.ARWI01000001_gene293	2.74e-138	404.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,45ZY1@72273|Thiotrichales	72273|Thiotrichales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_780169_2	1123518.ARWI01000001_gene292	0.0	1186.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,45ZTR@72273|Thiotrichales	72273|Thiotrichales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
k59_780169_3	1123518.ARWI01000001_gene291	9.86e-56	176.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,46168@72273|Thiotrichales	72273|Thiotrichales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_780169_4	1123518.ARWI01000001_gene290	1.05e-106	315.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,460E5@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_608744_1	1123514.KB905903_gene370	2.8e-80	268.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462CG@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM
k59_1347502_1	411154.GFO_0504	2.41e-57	182.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1I181@117743|Flavobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k59_1347502_2	1121931.AUHG01000015_gene1220	3.39e-54	179.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1HXKY@117743|Flavobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_441475_1	90814.KL370891_gene1871	7.51e-54	193.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZ2Z@1236|Gammaproteobacteria,461N6@72273|Thiotrichales	72273|Thiotrichales	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_9,SBP_bac_3
k59_329293_1	572480.Arnit_2863	6.18e-145	422.0	COG3014@1|root,COG3014@2|Bacteria,1PKX6@1224|Proteobacteria,42PQ4@68525|delta/epsilon subdivisions,2YNQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k59_329293_2	944547.ABLL_0354	1.25e-34	121.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2YPX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_727200_1	985255.APHJ01000021_gene1222	5.61e-49	159.0	2CH25@1|root,32U8R@2|Bacteria,4NTN2@976|Bacteroidetes,1I3VT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_727200_2	985255.APHJ01000021_gene1221	7.05e-34	124.0	COG3843@1|root,COG3843@2|Bacteria,4NI34@976|Bacteroidetes,1HXWW@117743|Flavobacteriia	976|Bacteroidetes	U	Relaxase/Mobilisation nuclease domain	bmgA	-	-	-	-	-	-	-	-	-	-	-	Relaxase
k59_103783_1	929558.SMGD1_0884	1.47e-112	332.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2YMKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_329321_1	938709.AUSH02000073_gene1784	0.000106	43.9	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_329321_2	1137281.D778_00939	9e-92	276.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1HWQX@117743|Flavobacteriia	976|Bacteroidetes	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_946378_1	1172190.M947_03865	8.54e-136	396.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2YMEB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_1516211_1	1380600.AUYN01000009_gene1904	6.18e-21	97.1	2A0VS@1|root,30P0U@2|Bacteria,4NPP3@976|Bacteroidetes,1I29C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1175479_1	1380600.AUYN01000009_gene976	3.33e-74	231.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_1175479_2	1484460.JSWG01000004_gene2654	3.6e-63	195.0	2AVR2@1|root,31MIB@2|Bacteria,4NQKM@976|Bacteroidetes,1I2UX@117743|Flavobacteriia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
k59_946389_2	1120705.FG95_02151	1.43e-05	45.1	28XTK@1|root,2ZJQ1@2|Bacteria,1MZJV@1224|Proteobacteria,2UCH0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized small protein (DUF2158)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2158
k59_946389_3	1172190.M947_05120	1.56e-29	105.0	2BMN5@1|root,32G7D@2|Bacteria,1PVKA@1224|Proteobacteria,434BX@68525|delta/epsilon subdivisions,2YSN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
k59_1626779_1	1124780.ANNU01000023_gene3193	9.36e-69	222.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,47JXW@768503|Cytophagia	976|Bacteroidetes	K	sigma54 specific, transcriptional regulator, Fis family	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_892817_1	1121875.KB907547_gene3503	6.42e-06	45.4	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,1I2S1@117743|Flavobacteriia	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
k59_1516231_1	411154.GFO_2686	1.33e-157	464.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1HY4T@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_668687_1	411154.GFO_1951	1.99e-109	324.0	COG2207@1|root,COG2207@2|Bacteria,4NNDN@976|Bacteroidetes,1I1T3@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_552952_1	1185766.DL1_21005	3.06e-36	130.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,2XNRI@285107|Thioclava	28211|Alphaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_552952_2	1185766.DL1_21000	6.88e-75	231.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,2XNSE@285107|Thioclava	28211|Alphaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	natD	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1741819_1	1121931.AUHG01000011_gene2317	4.01e-225	656.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,1HYFE@117743|Flavobacteriia	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos,ShlB
k59_1579277_1	929558.SMGD1_2439	4.15e-69	216.0	COG4649@1|root,COG4649@2|Bacteria,1Q2HI@1224|Proteobacteria,42VQJ@68525|delta/epsilon subdivisions,2YQ7B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_1579277_2	1172190.M947_00045	6.09e-25	95.1	COG0721@1|root,COG0721@2|Bacteria,1Q61J@1224|Proteobacteria,42VIQ@68525|delta/epsilon subdivisions,2YQAY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_618372_1	143224.JQMD01000002_gene2452	7.79e-11	65.1	COG0582@1|root,COG0582@2|Bacteria,4NI9Q@976|Bacteroidetes,1HZR0@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
k59_618372_2	926559.JoomaDRAFT_1231	4e-90	274.0	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes,1HXAM@117743|Flavobacteriia	976|Bacteroidetes	K	Pfam Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k59_1128646_1	1123518.ARWI01000001_gene2233	2.41e-143	411.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,46077@72273|Thiotrichales	72273|Thiotrichales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_1128646_2	317025.Tcr_0798	2.53e-130	381.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,460V5@72273|Thiotrichales	72273|Thiotrichales	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1128646_3	90814.KL370891_gene1429	3.02e-16	76.6	COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria,1SE1C@1236|Gammaproteobacteria,4636Z@72273|Thiotrichales	72273|Thiotrichales	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_1128646_4	90814.KL370891_gene1428	5.4e-168	475.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,4605M@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1011704_1	1121931.AUHG01000012_gene2917	1.26e-132	382.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1HXE2@117743|Flavobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_53100_1	317025.Tcr_0639	1.7e-101	311.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,460CP@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_451032_1	1237149.C900_02765	1.42e-57	189.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1298718_1	1137281.D778_00808	2.41e-22	94.4	2DBAY@1|root,2Z84S@2|Bacteria,4NGXD@976|Bacteroidetes,1HXHD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
k59_1298718_2	1380600.AUYN01000012_gene2988	9.39e-60	185.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1I2UU@117743|Flavobacteriia	976|Bacteroidetes	J	Translation initiation factor	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k59_1298718_3	391603.FBALC1_08623	1.21e-51	171.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1HWU5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_1408291_1	1122179.KB890469_gene601	1.51e-92	286.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_1408291_2	1122986.KB908326_gene529	2.45e-16	79.3	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_618412_1	411154.GFO_0648	4.05e-58	187.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_618412_2	411154.GFO_0649	1.44e-68	207.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1I2X0@117743|Flavobacteriia	976|Bacteroidetes	S	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
k59_167695_1	411154.GFO_3016	3.73e-73	229.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_167695_2	1250278.JQNQ01000001_gene1410	0.000219	44.7	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k59_1128690_1	945713.IALB_0492	6.84e-109	323.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU38550	Aminotran_4
k59_618424_1	929558.SMGD1_1844	5.44e-45	154.0	COG0688@1|root,COG0688@2|Bacteria,1P7K4@1224|Proteobacteria,42TG5@68525|delta/epsilon subdivisions,2YQIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_618424_2	929558.SMGD1_1843	1.54e-105	325.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1579342_1	572480.Arnit_3110	3.74e-40	145.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2YN4P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_1579342_2	572480.Arnit_3113	3.94e-111	326.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,42Q1Y@68525|delta/epsilon subdivisions,2YNR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_1298741_1	1453505.JASY01000007_gene1156	6.06e-114	333.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia,2NSGH@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_1298741_2	362418.IW19_21965	2.18e-46	155.0	COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes,1HZD8@117743|Flavobacteriia,2NSVI@237|Flavobacterium	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_508327_1	1178825.ALIH01000002_gene915	6.34e-16	83.6	COG2273@1|root,COG2273@2|Bacteria,4NHWA@976|Bacteroidetes,1HX44@117743|Flavobacteriia	976|Bacteroidetes	G	Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_618434_1	90814.KL370891_gene447	7.32e-24	92.0	2DRGH@1|root,33BMH@2|Bacteria,1NPG2@1224|Proteobacteria,1SHUG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k59_618434_2	90814.KL370891_gene448	6.27e-197	553.0	2DBHN@1|root,2Z9BF@2|Bacteria,1QWQ3@1224|Proteobacteria,1S0YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_279665_1	1197477.IA57_11015	6.33e-133	381.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_902562_1	1565129.JSFF01000004_gene3108	2.89e-119	374.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,2QA9P@267890|Shewanellaceae	1236|Gammaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1466734_1	926556.Echvi_1459	3.75e-17	78.6	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_1466734_2	1123277.KB893179_gene3132	2.23e-27	111.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_451134_1	572480.Arnit_0031	9.19e-137	400.0	COG1956@1|root,COG3604@1|root,COG1956@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2YNEN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_562725_1	572480.Arnit_1600	2.86e-162	466.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YMB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	abc transporter atp-binding protein	yheS	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1466770_1	1121931.AUHG01000011_gene2305	5.63e-57	186.0	2DUH4@1|root,33QM8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
k59_1466792_1	411154.GFO_1552	2.4e-99	306.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,4NF52@976|Bacteroidetes,1HWTJ@117743|Flavobacteriia	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,CitMHS_2,Na_sulph_symp,TrkA_C
k59_1408397_1	90814.KL370891_gene774	3.17e-09	56.6	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,460G9@72273|Thiotrichales	72273|Thiotrichales	L	Hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_1299177_1	1046627.BZARG_506	7.16e-116	339.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1HYA2@117743|Flavobacteriia	976|Bacteroidetes	EG	of the drug metabolite transporter (DMT) superfamily	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_508381_1	1336243.JAEA01000007_gene656	1.45e-73	244.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2TW58@28211|Alphaproteobacteria,1JRD1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	V	PFAM ABC transporter related	rbbA	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
k59_960274_1	504487.JCM19302_2514	2.58e-70	236.0	COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
k59_960274_2	1178825.ALIH01000016_gene617	2.17e-41	146.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_677852_1	1123518.ARWI01000001_gene1706	4.93e-149	442.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,461Y3@72273|Thiotrichales	72273|Thiotrichales	H	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_677860_1	563040.Saut_0642	9.54e-53	169.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2YSYY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_677860_2	563040.Saut_0643	2.57e-25	104.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2YMV7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_1299201_1	1123518.ARWI01000001_gene1084	3.62e-29	109.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,460HF@72273|Thiotrichales	72273|Thiotrichales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_1299201_2	1123518.ARWI01000001_gene1087	1.54e-41	150.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria,461VV@72273|Thiotrichales	72273|Thiotrichales	P	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_395435_1	1469557.JSWF01000036_gene790	6.31e-89	274.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_960291_1	362418.IW19_08760	1.35e-56	188.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia,2NSNP@237|Flavobacterium	976|Bacteroidetes	Q	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k59_960291_2	926559.JoomaDRAFT_3446	4.8e-36	136.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_621392_1	1353276.JADR01000011_gene1536	1.36e-125	360.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_621392_2	1178825.ALIH01000003_gene2143	2.79e-111	327.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
k59_621392_3	1178825.ALIH01000003_gene2144	1.16e-22	96.7	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k59_451922_1	709032.Sulku_1543	5.83e-171	499.0	COG2199@1|root,COG4564@1|root,COG3706@2|Bacteria,COG4564@2|Bacteria,1MX83@1224|Proteobacteria,43CSD@68525|delta/epsilon subdivisions,2YT21@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Pfam:Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_2,sCache_2
k59_1299225_1	525898.Sdel_1157	4.18e-61	199.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2YMD7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_1299225_2	469610.HMPREF0189_01648	5.72e-05	43.5	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2VV0R@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_847330_1	504487.JCM19302_1769	1.9e-93	285.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
k59_338959_1	90814.KL370891_gene1487	1.13e-43	153.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,461U0@72273|Thiotrichales	72273|Thiotrichales	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
k59_169534_1	1121912.AUHD01000001_gene2472	2.05e-21	87.0	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes,1I21F@117743|Flavobacteriia	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_169534_2	1380600.AUYN01000009_gene1705	1.02e-57	181.0	2AFZR@1|root,3163Q@2|Bacteria,4NQFG@976|Bacteroidetes,1I3HJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1638171_1	1392490.JHZX01000001_gene1428	4.27e-248	692.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_451945_1	745718.JADT01000005_gene24	2.67e-101	302.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1HWT4@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
k59_1525190_2	1178825.ALIH01000001_gene2471	9.51e-154	442.0	COG0366@1|root,COG0366@2|Bacteria,4PKH4@976|Bacteroidetes,1IJ8S@117743|Flavobacteriia	976|Bacteroidetes	G	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
k59_1694650_1	1380600.AUYN01000003_gene15	3.1e-111	330.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
k59_1638181_1	558884.JRGM01000150_gene3507	1.48e-60	193.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1Y5AQ@135624|Aeromonadales	135624|Aeromonadales	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k59_1638181_2	1121937.AUHJ01000001_gene710	6.78e-10	60.5	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,464QM@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	Belongs to the IlvD Edd family	edd	GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366	ILVD_EDD
k59_113_1	1565129.JSFF01000036_gene1430	5.74e-112	327.0	COG3608@1|root,COG3608@2|Bacteria,1QUH0@1224|Proteobacteria,1RUQ0@1236|Gammaproteobacteria,2Q8WC@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_56589_1	1392490.JHZX01000001_gene2154	2.57e-44	145.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1I2YP@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
k59_56589_2	1198452.Jab_2c29540	7.36e-43	145.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,2VUWB@28216|Betaproteobacteria,474QE@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
k59_56589_3	504487.JCM19302_3571	2.57e-106	311.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_56592_1	497321.C664_11230	1.75e-107	341.0	COG0247@1|root,COG0277@1|root,COG1145@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1145@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,2KUWB@206389|Rhodocyclales	206389|Rhodocyclales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_621443_2	1565129.JSFF01000017_gene2875	6.27e-28	102.0	COG3036@1|root,COG3036@2|Bacteria,1NH0E@1224|Proteobacteria,1SGZX@1236|Gammaproteobacteria,2QCZ1@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function	Z012_03065	-	-	ko:K09890	-	-	-	-	ko00000,ko03012	-	-	-	DUF331
k59_395500_1	411154.GFO_2893	4.83e-86	265.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_395500_2	411154.GFO_2893	1.72e-26	105.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_226075_1	572480.Arnit_1906	2.29e-78	236.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2YP4S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k59_847354_2	1178825.ALIH01000010_gene372	6.51e-149	427.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1HXR1@117743|Flavobacteriia	976|Bacteroidetes	P	Ca2 Na antiporter	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_847354_3	504487.JCM19302_2125	1.63e-233	644.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1HXPA@117743|Flavobacteriia	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_847354_5	1178825.ALIH01000010_gene375	2.27e-48	172.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
k59_1412276_1	572480.Arnit_2092	9.33e-21	90.5	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2YMQS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_1412276_2	572480.Arnit_2091	5.39e-165	464.0	COG0656@1|root,COG0656@2|Bacteria,1PGB3@1224|Proteobacteria,42PPT@68525|delta/epsilon subdivisions,2YN3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_1186341_1	717772.THIAE_04235	3.5e-168	477.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,461ZA@72273|Thiotrichales	72273|Thiotrichales	M	NAD-dependent epimerase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_1186341_2	1123517.JOMR01000001_gene1336	2.62e-61	199.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,4601V@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_621468_1	655815.ZPR_0608	4.04e-60	199.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
k59_677952_1	717774.Marme_3068	2.13e-45	154.0	COG2404@1|root,COG2404@2|Bacteria,1QW0R@1224|Proteobacteria,1T2U1@1236|Gammaproteobacteria,1XHTR@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1548485_3	929558.SMGD1_0624	1.36e-09	59.7	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2YMCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_362376_2	317025.Tcr_1603	1.11e-94	291.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,45ZWE@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1493624_1	411154.GFO_3530	5.16e-57	184.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_1493624_2	1121931.AUHG01000010_gene556	2.79e-14	68.9	COG3477@1|root,COG3477@2|Bacteria,4NN3J@976|Bacteroidetes,1I1EM@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1440)	-	-	-	ko:K08996	-	-	-	-	ko00000	-	-	-	DUF1440
k59_81499_1	1178825.ALIH01000005_gene189	1.03e-75	237.0	COG1835@1|root,COG1835@2|Bacteria,4PKKX@976|Bacteroidetes,1IJC6@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
k59_646129_1	944547.ABLL_0464	2.12e-17	77.8	COG1521@1|root,COG1521@2|Bacteria,1PZXA@1224|Proteobacteria,42RA8@68525|delta/epsilon subdivisions,2YP14@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_646129_2	572480.Arnit_0545	3.57e-134	381.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2YN1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_646129_3	572480.Arnit_0546	1.68e-93	277.0	COG0500@1|root,COG0500@2|Bacteria,1QWS3@1224|Proteobacteria,43CIB@68525|delta/epsilon subdivisions,2YTCY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
k59_1378962_1	411154.GFO_1747	6.38e-106	326.0	COG0514@1|root,COG0514@2|Bacteria,4NG10@976|Bacteroidetes,1HXWC@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ3	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_1435796_1	1353528.DT23_11340	2.4e-29	106.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2XNC6@285107|Thioclava	28211|Alphaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
k59_1435796_2	1472418.BBJC01000001_gene103	5.94e-16	73.2	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
k59_1493634_1	1123518.ARWI01000001_gene133	5.58e-93	272.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,46105@72273|Thiotrichales	72273|Thiotrichales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_1493634_2	1123517.JOMR01000001_gene1010	9.87e-60	196.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,46035@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_362390_1	1121931.AUHG01000011_gene1939	3.82e-112	345.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1HZ6R@117743|Flavobacteriia	976|Bacteroidetes	P	Outer membrane receptor for Fe3 -dicitrate	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_927439_1	945713.IALB_0243	2.58e-113	336.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1493641_1	497321.C664_11107	2.95e-102	303.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,2KUKV@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1324985_1	745718.JADT01000001_gene1749	2.12e-69	223.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1HXNP@117743|Flavobacteriia	976|Bacteroidetes	I	Biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1324985_2	1380600.AUYN01000009_gene2002	2.18e-87	271.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HYE9@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_477042_1	411154.GFO_0485	1.14e-69	212.0	2AFZR@1|root,3163Q@2|Bacteria,4NQFG@976|Bacteroidetes,1I3HJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_307171_1	1189620.AJXL01000041_gene577	3.17e-103	328.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2NUYY@237|Flavobacterium	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,MAM,PepSY,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,fn3
k59_871653_1	62928.azo0418	1.08e-17	82.4	COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria,2KZNR@206389|Rhodocyclales	206389|Rhodocyclales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
k59_871653_2	62928.azo0419	6.81e-36	125.0	COG0848@1|root,COG0848@2|Bacteria,1NFDF@1224|Proteobacteria,2VWMV@28216|Betaproteobacteria,2KZ18@206389|Rhodocyclales	206389|Rhodocyclales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k59_194653_1	1380600.AUYN01000001_gene2569	4e-159	454.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_194653_2	1286632.P278_08170	1.67e-113	333.0	COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
k59_83838_1	1123514.KB905899_gene1009	7.19e-83	254.0	2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,46129@72273|Thiotrichales	72273|Thiotrichales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
k59_309502_1	1123514.KB905899_gene1311	3.18e-41	139.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_309502_2	90814.KL370891_gene995	5.91e-42	144.0	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria	1224|Proteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1665283_1	1121405.dsmv_3693	1.5e-29	119.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	EIIA-man,HTH_21,PRD,PTS_EIIA_2,Sigma54_activat,rve
k59_1438111_1	42565.FP66_01790	3.38e-72	223.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XIT9@135619|Oceanospirillales	135619|Oceanospirillales	E	phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_873981_1	1380600.AUYN01000010_gene934	1.19e-84	257.0	COG4768@1|root,COG4768@2|Bacteria,4NIFH@976|Bacteroidetes,1I01R@117743|Flavobacteriia	976|Bacteroidetes	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_873981_2	1178825.ALIH01000006_gene1384	6.54e-168	478.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1HX39@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_873981_3	504487.JCM19302_2972	4.81e-71	218.0	COG0494@1|root,COG0494@2|Bacteria,4NHER@976|Bacteroidetes,1HWUJ@117743|Flavobacteriia	976|Bacteroidetes	L	GDP-mannose pyrophosphatase	nudK	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_1327397_1	504487.JCM19302_701	9.15e-117	339.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_760390_1	411154.GFO_3351	1.52e-189	530.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1609931_1	709032.Sulku_1505	1.32e-229	653.0	COG2199@1|root,COG3706@2|Bacteria,1R1K2@1224|Proteobacteria,42YWW@68525|delta/epsilon subdivisions,2YR1I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k59_196957_1	317025.Tcr_0840	2.78e-80	259.0	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,460IM@72273|Thiotrichales	72273|Thiotrichales	S	Carboxysome shell peptide mid-region	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
k59_760399_1	563040.Saut_0891	9.04e-76	231.0	COG2050@1|root,COG2050@2|Bacteria,1N1PP@1224|Proteobacteria,42TRH@68525|delta/epsilon subdivisions,2YPTG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	thioesterase	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_253918_1	1123518.ARWI01000001_gene1596	3.15e-81	251.0	COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,461KZ@72273|Thiotrichales	72273|Thiotrichales	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	S6PP
k59_760406_1	1163617.SCD_n02290	3.26e-30	124.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
k59_760407_1	1121931.AUHG01000015_gene1181	6.22e-103	318.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,4NJDM@976|Bacteroidetes,1I8IH@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
k59_1381258_1	318161.Sden_3065	1.91e-24	101.0	COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,1RQYY@1236|Gammaproteobacteria,2QEKP@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
k59_1381258_2	323850.Shew_3100	2.33e-56	178.0	COG0589@1|root,COG0589@2|Bacteria,1PE59@1224|Proteobacteria,1RVVX@1236|Gammaproteobacteria,2QBTG@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_929791_1	1286632.P278_15590	8.21e-45	153.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1HZ91@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1098983_1	1121931.AUHG01000010_gene185	1.13e-54	175.0	2EHX5@1|root,3385X@2|Bacteria,4NVDX@976|Bacteroidetes,1I67H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1098983_2	1121931.AUHG01000010_gene183	5.06e-163	475.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1HXDK@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
k59_706779_1	653733.Selin_2186	1.67e-95	301.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,PHP,PHP_C
k59_1269168_1	317025.Tcr_1796	4.35e-57	188.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,460DZ@72273|Thiotrichales	72273|Thiotrichales	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1269168_2	317025.Tcr_1797	8.42e-109	332.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZPC@72273|Thiotrichales	72273|Thiotrichales	G	PFAM alpha amylase, catalytic	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k59_139128_1	504487.JCM19302_1373	2.69e-69	212.0	2B8FQ@1|root,321QT@2|Bacteria,4NQ2U@976|Bacteroidetes,1I3E8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1665349_1	504487.JCM19302_1847	3.16e-29	112.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1HX81@117743|Flavobacteriia	976|Bacteroidetes	I	synthase	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1665349_2	398720.MED217_03775	1.37e-34	131.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia,2XIGX@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_706787_1	563040.Saut_2031	2.69e-169	483.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2YMCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iIT341.HP0476	tRNA-synt_1c
k59_706787_2	929558.SMGD1_1080	8.89e-67	212.0	COG0760@1|root,COG0760@2|Bacteria,1N20M@1224|Proteobacteria,42SXW@68525|delta/epsilon subdivisions,2YPHS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N,SurA_N_3
k59_818829_1	945713.IALB_2664	8.26e-09	55.1	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_818829_2	240015.ACP_3078	0.000315	45.8	COG2353@1|root,COG2353@2|Bacteria,3Y4PV@57723|Acidobacteria,2JMPN@204432|Acidobacteriia	204432|Acidobacteriia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_139131_1	1168067.JAGP01000001_gene212	5.71e-307	848.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,45ZRU@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_253974_1	1392488.JHZY01000002_gene818	2.56e-87	278.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,1HWZE@117743|Flavobacteriia,2XJVP@283735|Leeuwenhoekiella	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	ybaL_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
k59_1155552_1	675816.VIA_001852	1.79e-28	118.0	COG2010@1|root,COG2133@1|root,COG5295@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	shp	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	DUF1924,GSDH
k59_422436_1	572480.Arnit_2379	1.11e-23	99.4	COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,42MQF@68525|delta/epsilon subdivisions,2YTD6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k59_422436_2	944547.ABLL_2107	8.54e-48	155.0	COG0011@1|root,COG0011@2|Bacteria,1N2GU@1224|Proteobacteria,42UPF@68525|delta/epsilon subdivisions,2YQEK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k59_1438198_1	929558.SMGD1_2731	7.34e-124	359.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,42NGI@68525|delta/epsilon subdivisions,2YNFE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	flagellar basal body	flgG2	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_1779009_1	1408473.JHXO01000005_gene1530	8.49e-48	184.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_1099026_1	1123518.ARWI01000001_gene2207	1.46e-64	221.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,461XY@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_1099026_2	90814.KL370891_gene1455	5.58e-12	62.8	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1RMZM@1236|Gammaproteobacteria,460MB@72273|Thiotrichales	72273|Thiotrichales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_1496156_1	1123518.ARWI01000001_gene1751	2.4e-127	372.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,4605U@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_591461_1	305700.B447_02346	1.19e-112	346.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,2KUE2@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1327506_1	572480.Arnit_2828	3e-65	209.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_1327506_2	572480.Arnit_2829	3.06e-120	355.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2YMAR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_706834_1	746697.Aeqsu_0613	4.58e-19	82.4	2B7X4@1|root,32143@2|Bacteria,4NNUI@976|Bacteroidetes,1I2MC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k59_706834_2	1137281.D778_00518	1.04e-125	363.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_706834_3	1137281.D778_00519	1.83e-97	303.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_10,TPR_12,TPR_7,TPR_8,Y_Y_Y
k59_422457_1	1336803.PHEL49_0743	6.29e-38	133.0	2A813@1|root,30X1F@2|Bacteria,4NP0A@976|Bacteroidetes,1I2B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_422457_2	63737.Npun_R3733	1.08e-07	53.5	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1G1PX@1117|Cyanobacteria,1HKMW@1161|Nostocales	1117|Cyanobacteria	T	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
k59_535328_1	504487.JCM19302_614	1.24e-126	363.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,1HYMQ@117743|Flavobacteriia	976|Bacteroidetes	G	Aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k59_591479_1	1380600.AUYN01000006_gene332	1.52e-63	203.0	2CG2P@1|root,334R2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1665413_2	572480.Arnit_0829	3.23e-42	142.0	COG0705@1|root,COG0705@2|Bacteria,1NH9I@1224|Proteobacteria,42RJD@68525|delta/epsilon subdivisions,2YPF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf01694	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_1438240_1	1380600.AUYN01000010_gene838	8.59e-54	172.0	2B8FQ@1|root,321QT@2|Bacteria,4NQ2U@976|Bacteroidetes,1I3E8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1665417_1	859657.RPSI07_mp0685	1.39e-59	194.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2VIJS@28216|Betaproteobacteria,1K156@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	BON,OmpA
k59_818898_1	90813.JQMT01000001_gene603	2.22e-44	144.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,4615Q@72273|Thiotrichales	72273|Thiotrichales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_818898_2	1123518.ARWI01000001_gene552	1.11e-14	72.8	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_254053_1	1178825.ALIH01000006_gene1421	3.92e-110	338.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_982051_1	640081.Dsui_0656	1.91e-25	110.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_1381364_1	90814.KL370892_gene2286	1.73e-76	249.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,460JF@72273|Thiotrichales	72273|Thiotrichales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_48766_2	1484460.JSWG01000015_gene1004	4.72e-29	112.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,1HWNQ@117743|Flavobacteriia	976|Bacteroidetes	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_558079_1	1121931.AUHG01000011_gene2160	1.84e-63	211.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_613795_1	1004149.AFOE01000025_gene3224	6.94e-08	59.3	COG2885@1|root,COG2885@2|Bacteria,4NI3U@976|Bacteroidetes,1I04E@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
k59_337840_3	1178825.ALIH01000020_gene2706	1.43e-28	109.0	COG4083@1|root,COG4083@2|Bacteria	2|Bacteria	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
k59_112286_1	90814.KL370891_gene1414	1.88e-10	60.1	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,45ZPU@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_112286_2	717773.Thicy_0633	5.77e-39	139.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,46031@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_1693317_1	411154.GFO_1616	4.26e-108	330.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_1577706_1	1191523.MROS_0147	3.72e-80	250.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
k59_449562_1	1123517.JOMR01000001_gene1920	8.08e-11	60.8	COG0500@1|root,COG2226@2|Bacteria,1MYW1@1224|Proteobacteria,1S707@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_506854_1	999415.HMPREF9943_00236	4.2e-13	70.5	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,3VPCV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	tRNA nucleotidyltransferase poly(A) polymerase family protein	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
k59_676991_2	1443125.Z962_11095	1.09e-09	62.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,36DV2@31979|Clostridiaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
k59_1183967_1	880073.Calab_1916	3.93e-15	76.6	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_449592_1	945713.IALB_1923	1.22e-26	104.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
k59_449592_2	945713.IALB_1924	6.36e-55	181.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	hpnC	-	2.5.1.32,2.5.1.99,4.2.3.156	ko:K02291,ko:K21679	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
k59_843557_1	926556.Echvi_3252	8.13e-19	86.3	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
k59_1183988_2	1165841.SULAR_03862	5.16e-91	283.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42YPF@68525|delta/epsilon subdivisions,2YRMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k59_166283_1	95619.PM1_0201255	7.96e-55	183.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	ssg	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
k59_449609_1	616991.JPOO01000003_gene1240	7.12e-88	269.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,1I0KC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_51955_1	305700.B447_18823	3.35e-71	225.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,2KV2X@206389|Rhodocyclales	206389|Rhodocyclales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_51961_1	211586.SO_3270	1.13e-101	305.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,2Q91M@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1297362_1	326298.Suden_1530	1.05e-142	427.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_1693415_1	367737.Abu_2329	7.71e-25	112.0	COG3437@1|root,COG3850@1|root,COG3437@2|Bacteria,COG3850@2|Bacteria,1QUN9@1224|Proteobacteria,42QEK@68525|delta/epsilon subdivisions,2YNC1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_1407275_1	572480.Arnit_1453	2.44e-133	387.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2YN2E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COG1252 NADH dehydrogenase FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1297384_1	1168034.FH5T_15100	4.49e-111	338.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_900969_1	1123518.ARWI01000001_gene763	1.99e-32	121.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,461ZK@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
k59_677069_1	1121931.AUHG01000010_gene756	3.95e-72	239.0	COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,1HXUZ@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
k59_1524909_1	572480.Arnit_2583	2.11e-107	315.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2YNDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_506955_1	313612.L8106_11247	5.8e-31	126.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_337999_1	929558.SMGD1_2646	5.61e-116	342.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2YMKF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_953406_1	1458275.AZ34_13435	1.35e-76	247.0	COG3206@1|root,COG3206@2|Bacteria,1RK0N@1224|Proteobacteria,2VHPS@28216|Betaproteobacteria,4AA01@80864|Comamonadaceae	28216|Betaproteobacteria	M	Chain length determinant protein	gumC	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k59_677090_2	90814.KL370891_gene263	5.91e-150	448.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_166365_1	563040.Saut_1933	2.43e-68	211.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2YNYN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	riboflavin synthase alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_166365_2	50960.LS81_03115	1.46e-24	95.1	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,42VB5@68525|delta/epsilon subdivisions,2YPVJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	of the cytoplasmic domain of flagellar protein FhlB	flhB2	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k59_166365_3	697282.Mettu_2965	1.48e-32	129.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9
k59_901002_1	1123367.C666_11485	2.28e-10	61.2	COG0210@1|root,COG0210@2|Bacteria,1R645@1224|Proteobacteria,2VMXD@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C
k59_338019_1	1121931.AUHG01000010_gene427	3.03e-13	67.0	2EQ2R@1|root,33HP4@2|Bacteria,4NZ0U@976|Bacteroidetes,1I6WR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_338019_2	411154.GFO_3444	1.28e-89	282.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-glucosidase	susB	GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
k59_561288_1	572480.Arnit_0405	1.71e-70	218.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,42Q2R@68525|delta/epsilon subdivisions,2YNDK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
k59_561288_2	572480.Arnit_0406	1.08e-52	172.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2YMXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter	-	-	-	ko:K15555,ko:K15578	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00436,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1,3.A.1.17.2	-	-	ABC_tran
k59_392992_1	1123514.KB905899_gene507	1.95e-116	344.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,45ZWS@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_224663_1	1380600.AUYN01000001_gene2235	1.85e-32	119.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1HWQ2@117743|Flavobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_1297466_1	694427.Palpr_0909	5.59e-109	317.0	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,2FQ64@200643|Bacteroidia,22Y8Z@171551|Porphyromonadaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	vat_2	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k59_166413_1	1347342.BN863_4170	3.83e-75	229.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1I35P@117743|Flavobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
k59_166413_2	1380600.AUYN01000009_gene1341	8.49e-42	144.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1HWJM@117743|Flavobacteriia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_1184134_1	1283300.ATXB01000002_gene2697	5.48e-74	248.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XG5E@135618|Methylococcales	135618|Methylococcales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
k59_278703_1	929558.SMGD1_1793	1.33e-87	268.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2YMJW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N
k59_278703_2	326298.Suden_1747	1.77e-11	59.3	29H9G@1|root,30470@2|Bacteria,1QR1D@1224|Proteobacteria,42TWI@68525|delta/epsilon subdivisions,2YPSP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1297494_1	90814.KL370891_gene945	1.03e-95	300.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,45ZXP@72273|Thiotrichales	72273|Thiotrichales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_52101_1	1347342.BN863_34310	8.03e-75	236.0	COG5571@1|root,COG5571@2|Bacteria,4NFAE@976|Bacteroidetes,1HZA2@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
k59_1693547_1	992406.RIA_0801	3.73e-19	93.6	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
k59_843735_1	1408473.JHXO01000009_gene3272	1.93e-30	112.0	COG1595@1|root,COG1595@2|Bacteria,4NNRM@976|Bacteroidetes,2G2W6@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_278742_1	1121931.AUHG01000018_gene1356	7.16e-88	259.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,1I275@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_278742_2	411154.GFO_0332	3.27e-17	79.3	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,1HX7F@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_617155_1	929558.SMGD1_1693	2.63e-100	308.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2YN0B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_166483_1	1123518.ARWI01000001_gene186	6.5e-43	155.0	COG1275@1|root,COG1275@2|Bacteria	2|Bacteria	P	C4-dicarboxylate transporter malic acid transport protein	tehA	-	-	ko:K03304	-	-	-	-	ko00000,ko02000	2.A.16.1	-	-	SLAC1
k59_561408_1	1121931.AUHG01000010_gene857	3.15e-117	355.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
k59_1184189_2	1178825.ALIH01000015_gene1901	8.67e-279	766.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1HX2J@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_1184189_3	1121912.AUHD01000014_gene1032	2.41e-169	479.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1HWW7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1184189_4	1380600.AUYN01000001_gene2306	2.49e-293	820.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k59_1184192_1	1121931.AUHG01000016_gene1122	3.5e-99	295.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,1HYJ8@117743|Flavobacteriia	976|Bacteroidetes	K	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
k59_1297562_2	1232683.ADIMK_1119	1.08e-57	186.0	2DBYH@1|root,2ZBV5@2|Bacteria,1RA73@1224|Proteobacteria,1SY9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1297562_3	941449.dsx2_0614	2.08e-07	50.4	2AD7J@1|root,312WH@2|Bacteria,1RHF8@1224|Proteobacteria,42U6I@68525|delta/epsilon subdivisions,2WR16@28221|Deltaproteobacteria,2MCRV@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
k59_901152_1	983545.Glaag_2397	4.69e-22	92.0	COG0848@1|root,COG0848@2|Bacteria,1N9Y7@1224|Proteobacteria,1SCI5@1236|Gammaproteobacteria,46C22@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_901152_2	1198232.CYCME_2302	1.6e-11	64.3	COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,1S81P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_953528_1	1178825.ALIH01000006_gene1503	5.89e-75	227.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,1I2T9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
k59_338175_1	1123228.AUIH01000003_gene871	4.73e-25	100.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria,1XHWU@135619|Oceanospirillales	135619|Oceanospirillales	T	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rstA	-	-	ko:K07661	ko02020,map02020	M00446	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_901160_1	326298.Suden_1689	3.15e-115	342.0	COG1363@1|root,COG1363@2|Bacteria,1MWQV@1224|Proteobacteria,42Y9B@68525|delta/epsilon subdivisions,2YR4Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_1184224_1	926556.Echvi_1737	8.57e-52	179.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_953529_1	1380600.AUYN01000009_gene1214	7.59e-218	625.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1HXB5@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
k59_953529_3	1250005.PHEL85_1541	2.51e-210	583.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia,3VW27@52959|Polaribacter	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_1465343_1	760154.Sulba_0280	1.68e-18	79.3	COG3668@1|root,COG3668@2|Bacteria,1N2I9@1224|Proteobacteria,42WVF@68525|delta/epsilon subdivisions,2YSZY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k59_1465343_2	709032.Sulku_0810	2.26e-25	98.2	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_1465343_3	1355368.JART01000008_gene1699	1.3e-38	134.0	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,42UPK@68525|delta/epsilon subdivisions,2YQYC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CENP-B_N,Resolvase
k59_1297611_1	929558.SMGD1_2137	5.58e-104	323.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_507169_1	76114.ebA3926	0.000418	48.1	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria,2KXTR@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1010437_1	1121931.AUHG01000018_gene1346	4.5e-198	552.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia	976|Bacteroidetes	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_1010437_2	411154.GFO_0342	2.44e-36	130.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,1HWRY@117743|Flavobacteriia	976|Bacteroidetes	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_1297632_1	1380600.AUYN01000009_gene1197	3.84e-132	407.0	COG0460@1|root,COG0527@1|root,COG2021@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,COG2021@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Abhydrolase_1,Homoserine_dh,NAD_binding_3
k59_1069783_1	1123228.AUIH01000021_gene128	1.95e-75	241.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,1RQM5@1236|Gammaproteobacteria,1XIBZ@135619|Oceanospirillales	135619|Oceanospirillales	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
k59_561495_1	1122201.AUAZ01000034_gene3500	3.94e-67	212.0	COG0034@1|root,COG0034@2|Bacteria,1MWHP@1224|Proteobacteria,1RMGF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	glutamine amidotransferase	-	-	2.1.1.21	ko:K22081	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GATase_6
k59_561495_2	317025.Tcr_1345	1.18e-23	99.8	COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,1RMRQ@1236|Gammaproteobacteria,461YT@72273|Thiotrichales	72273|Thiotrichales	C	Glutamate synthase	-	-	2.1.1.21	ko:K22082	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG
k59_953567_1	504487.JCM19302_3149	5.21e-113	327.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1HXZA@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_953567_2	504487.JCM19302_3150	4.7e-49	157.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1I45R@117743|Flavobacteriia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_1465401_1	1347342.BN863_35460	8.03e-161	468.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1HXAH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_959851_1	1121931.AUHG01000015_gene1185	4.03e-199	581.0	COG1629@1|root,COG1629@2|Bacteria,4PM06@976|Bacteroidetes,1IJK3@117743|Flavobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_917009_1	572480.Arnit_2363	1.47e-101	303.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2YN3Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0663	Chorismate_synt
k59_747593_1	1122225.AULQ01000001_gene1935	6.66e-111	332.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
k59_747593_2	1178825.ALIH01000015_gene1882	3.55e-128	369.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,1HYZT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747593_3	1380600.AUYN01000001_gene2327	6.03e-08	53.9	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,1I24J@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
k59_804747_1	1121931.AUHG01000010_gene471	5.28e-24	96.7	COG2930@1|root,COG2930@2|Bacteria,4NP71@976|Bacteroidetes,1I20I@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Family of	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_804747_2	746697.Aeqsu_1763	8.97e-33	126.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
k59_1195952_1	1441930.Z042_16785	2.46e-17	79.7	28MCI@1|root,2ZAQM@2|Bacteria,1MWK7@1224|Proteobacteria,1RQF7@1236|Gammaproteobacteria,400JG@613|Serratia	1236|Gammaproteobacteria	S	MoaF C-terminal domain	moaF	-	-	-	-	-	-	-	-	-	-	-	MoaF,MoaF_C
k59_1425406_1	318167.Sfri_2298	1.48e-27	106.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,2QAD7@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_1425406_2	425104.Ssed_1871	4.03e-39	144.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,2Q8R7@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_70605_1	1121912.AUHD01000004_gene2231	7.74e-65	214.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1313623_1	326298.Suden_1802	2.55e-46	156.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_1313623_2	1172190.M947_04270	6.45e-55	181.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2YMQW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_183733_1	1123518.ARWI01000001_gene766	6.16e-121	360.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,45ZYZ@72273|Thiotrichales	72273|Thiotrichales	U	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_1708522_1	1123514.KB905899_gene1906	2.58e-147	437.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_296174_1	504487.JCM19302_2809	6.38e-42	143.0	2DJSG@1|root,32UDQ@2|Bacteria,4NUK1@976|Bacteroidetes,1I4BP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3157
k59_409163_2	637905.SVI_0281	2.3e-80	253.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,2Q9UN@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	csrD	GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016070,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0031323,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K18765	-	-	-	-	ko00000,ko03019	-	-	-	EAL,GAPES4,GGDEF
k59_578808_1	1347393.HG726020_gene1620	5.04e-07	56.2	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,2FN1I@200643|Bacteroidia,4AN76@815|Bacteroidaceae	976|Bacteroidetes	N	COG NOG06100 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	TIG
k59_409166_1	1121918.ARWE01000001_gene3559	5.47e-85	277.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1,sCache_2
k59_1085891_1	411154.GFO_0393	7.01e-88	289.0	COG1345@1|root,COG3209@1|root,COG3391@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
k59_70632_1	411154.GFO_0986	9.01e-100	292.0	COG2860@1|root,COG2860@2|Bacteria,4NEXS@976|Bacteroidetes,1HX20@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
k59_1482464_1	42254.XP_004616151.1	1.83e-13	70.1	COG2017@1|root,KOG1604@2759|Eukaryota,39TA3@33154|Opisthokonta,3BJ1Q@33208|Metazoa,3CZZ7@33213|Bilateria,488K7@7711|Chordata,492AD@7742|Vertebrata,3J7WK@40674|Mammalia	33208|Metazoa	G	aldose 1-epimerase activity	GALM	GO:0003674,GO:0003824,GO:0004034,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k59_1313667_1	367336.OM2255_10051	3.02e-28	103.0	2CFVG@1|root,3346Y@2|Bacteria,1NFC4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1313667_2	1107311.Q767_03110	1.21e-16	73.6	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia,2NWT5@237|Flavobacterium	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
k59_1538057_1	1537917.JU82_10415	3.97e-79	246.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2YM81@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_692412_1	563040.Saut_1662	1.3e-72	224.0	29VYJ@1|root,30HGQ@2|Bacteria,1Q33E@1224|Proteobacteria,42WQE@68525|delta/epsilon subdivisions,2YQMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_692419_1	323850.Shew_2946	3.49e-44	148.0	2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria,2QCMD@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_804799_1	572480.Arnit_2838	4.02e-61	192.0	2B2RM@1|root,31VBT@2|Bacteria,1QT8Q@1224|Proteobacteria,433CR@68525|delta/epsilon subdivisions,2YSPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1595969_1	1123518.ARWI01000001_gene86	3.39e-09	55.1	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,460RC@72273|Thiotrichales	72273|Thiotrichales	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_1595969_2	90814.KL370891_gene1187	4.31e-89	262.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,460VS@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_409203_1	153948.NAL212_1841	2.93e-28	115.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2VK56@28216|Betaproteobacteria,371RV@32003|Nitrosomonadales	28216|Betaproteobacteria	CP	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05559	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
k59_409203_2	929558.SMGD1_2819	1.94e-28	113.0	COG0419@1|root,COG0419@2|Bacteria,1Q57D@1224|Proteobacteria,42NIY@68525|delta/epsilon subdivisions,2YNHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	P-loop containing region of AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1538075_2	655815.ZPR_3134	1.44e-25	104.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1HYDV@117743|Flavobacteriia	976|Bacteroidetes	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_747652_1	1296415.JACC01000001_gene3416	1.68e-157	452.0	COG0438@1|root,COG0438@2|Bacteria,4NHH5@976|Bacteroidetes,1IIKF@117743|Flavobacteriia,2YIXW@290174|Aquimarina	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_13036_1	938709.AUSH02000018_gene1145	2.66e-09	58.2	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
k59_13036_2	391587.KAOT1_13912	2.01e-127	369.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_13036_3	1121912.AUHD01000002_gene3242	1.29e-211	592.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_13036_4	1137281.D778_02842	2.18e-114	334.0	COG0670@1|root,COG0670@2|Bacteria,4NFZ7@976|Bacteroidetes,1HYR0@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
k59_13036_5	641526.ADIWIN_1645	1.62e-52	171.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia	976|Bacteroidetes	S	zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
k59_521843_1	317025.Tcr_1550	1.18e-105	336.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,45ZSY@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1085926_1	1392489.JPOL01000002_gene1193	9.73e-79	259.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2XK3H@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1482497_1	1298593.TOL_3135	1.49e-17	84.0	COG3290@1|root,COG5001@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	morA	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,dCache_2
k59_1425472_1	1123037.AUDE01000021_gene2220	7.81e-212	616.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mexF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1595990_1	1178825.ALIH01000001_gene2476	1.19e-98	299.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
k59_804820_1	1120951.AUBG01000015_gene3469	2.73e-12	66.6	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IJAQ@117743|Flavobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
k59_804820_2	411154.GFO_3290	2.2e-135	388.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_1255942_1	1484460.JSWG01000004_gene2593	3.34e-124	378.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_806868_1	1380600.AUYN01000009_gene967	2.6e-178	553.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k59_1032432_1	90814.KL370891_gene55	1.21e-90	291.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_9
k59_1032432_2	317025.Tcr_2007	4.78e-94	289.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,460BC@72273|Thiotrichales	72273|Thiotrichales	Q	transporter, dctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1427401_1	1415778.JQMM01000001_gene126	1.27e-86	270.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1J53G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_862820_1	1347342.BN863_8880	3.47e-36	125.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1I22D@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
k59_862820_2	1178825.ALIH01000010_gene463	1.14e-41	148.0	COG0545@1|root,COG0545@2|Bacteria,4NJPK@976|Bacteroidetes,1HY2J@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_128338_1	1123518.ARWI01000001_gene245	9.84e-184	522.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,4608Y@72273|Thiotrichales	72273|Thiotrichales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_128338_2	998088.B565_2218	4.23e-113	328.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1Y3Y9@135624|Aeromonadales	135624|Aeromonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_128338_3	1123518.ARWI01000001_gene243	7.38e-129	375.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,46052@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_1654128_1	1120951.AUBG01000003_gene2821	4.8e-86	266.0	COG0027@1|root,COG0027@2|Bacteria,4PNXZ@976|Bacteroidetes	976|Bacteroidetes	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
k59_1654128_2	1121931.AUHG01000011_gene2341	1.27e-37	137.0	COG0399@1|root,COG0399@2|Bacteria,4NGI4@976|Bacteroidetes,1HYZI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_862827_1	411154.GFO_0838	3.43e-125	368.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1HY02@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
k59_1257946_1	94122.Shewana3_3552	6.5e-29	106.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,1SYSB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
k59_1257946_2	319224.Sputcn32_3192	1.94e-10	58.5	COG0526@1|root,COG0526@2|Bacteria,1NIFY@1224|Proteobacteria,1SHJ0@1236|Gammaproteobacteria,2QBX9@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	TraF
k59_1767298_1	62928.azo0535	2.54e-55	176.0	COG2703@1|root,COG2703@2|Bacteria,1MZJ3@1224|Proteobacteria,2VVGT@28216|Betaproteobacteria,2KZ1F@206389|Rhodocyclales	206389|Rhodocyclales	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1484552_1	709032.Sulku_1240	3.89e-39	145.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1484552_2	1249480.B649_06360	4.63e-15	75.5	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1484552_3	929558.SMGD1_1838	2.8e-36	130.0	28M05@1|root,2ZAF9@2|Bacteria,1MY5U@1224|Proteobacteria,42MJP@68525|delta/epsilon subdivisions,2YMVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	General glycosylation pathway protein	pglG	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_1370345_1	1178482.BJB45_00220	1.56e-59	187.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1XHWV@135619|Oceanospirillales	135619|Oceanospirillales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_1370345_2	589873.EP13_16700	2.94e-21	84.7	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,468BZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Ribosomal protein L30	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_1370345_3	1123228.AUIH01000024_gene3233	6.2e-40	135.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XJJ2@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_1032450_1	1172190.M947_03915	6.08e-152	434.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2YMBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_1257955_1	323850.Shew_2127	1.19e-92	282.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,2QA99@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_918989_1	411154.GFO_3541	2.53e-170	482.0	COG2819@1|root,COG2819@2|Bacteria,4NGS5@976|Bacteroidetes,1HYN9@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_918989_2	411154.GFO_3542	6.04e-38	135.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_1540015_1	1121931.AUHG01000019_gene3025	4.55e-133	387.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_1315806_1	1379698.RBG1_1C00001G0404	5.09e-16	73.9	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
k59_1315806_2	1191523.MROS_1751	1.27e-09	60.5	COG0061@1|root,COG0061@2|Bacteria	2|Bacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
k59_1257962_1	1168067.JAGP01000001_gene1930	3.07e-137	402.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,46012@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_637477_1	1355374.JARU01000001_gene320	4.08e-89	270.0	COG2842@1|root,COG2842@2|Bacteria,1PSN7@1224|Proteobacteria,42SI9@68525|delta/epsilon subdivisions,2YRDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
k59_806909_1	1128421.JAGA01000002_gene1416	3.61e-46	168.0	COG2605@1|root,COG2605@2|Bacteria,2NP6Q@2323|unclassified Bacteria	2|Bacteria	S	GHMP kinases C terminal	hddA	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_806909_2	469618.FVAG_02119	1.42e-10	63.9	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83	ko:K00966,ko:K03273,ko:K15669	ko00051,ko00520,ko00540,ko01100,ko01110,map00051,map00520,map00540,map01100,map01110	M00064,M00114,M00361,M00362	R00885,R05647,R09771,R09772	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase
k59_298280_1	717773.Thicy_0224	3.73e-15	74.3	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,4607R@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_298280_2	317025.Tcr_0608	8.37e-87	271.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,4602P@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_242250_1	1304275.C41B8_01580	3.28e-113	339.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,1RN0D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	required for the utilization of tricarballylate as a carbon and energy source by S. enterica	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
k59_1654167_1	1197477.IA57_12335	4.82e-111	325.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_523948_1	323850.Shew_0444	4.84e-23	101.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,2QA7M@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k59_1710670_1	179408.Osc7112_0508	1.82e-22	102.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG3322@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3322@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1710670_2	1382306.JNIM01000001_gene3271	1.19e-13	64.7	2DEPM@1|root,2ZNRD@2|Bacteria,2G9FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1710670_3	1484460.JSWG01000015_gene1026	3.62e-180	568.0	COG1345@1|root,COG1361@1|root,COG3227@1|root,COG3420@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3227@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,Laminin_G_3,MAM
k59_1540063_1	391603.FBALC1_15707	7.49e-30	111.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_523972_1	85643.Tmz1t_2368	1.13e-41	143.0	COG1961@1|root,COG1961@2|Bacteria,1RC1A@1224|Proteobacteria,2WEHA@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
k59_862896_1	572480.Arnit_0641	1.42e-12	74.3	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NMT1,PAS_3,PAS_9,SBP_bac_3,dCache_2
k59_1654197_1	318161.Sden_2000	5.78e-136	410.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,2Q9P1@267890|Shewanellaceae	1236|Gammaproteobacteria	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199	Aldedh,Fe-ADH
k59_72735_1	1172190.M947_04685	4.79e-65	203.0	2BTJ1@1|root,32NRK@2|Bacteria,1Q3XC@1224|Proteobacteria,42RS4@68525|delta/epsilon subdivisions,2YPVI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
k59_141236_1	983544.Lacal_0021	9.98e-145	430.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1552975_1	1484460.JSWG01000015_gene936	7.93e-197	555.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1HX9Z@117743|Flavobacteriia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
k59_1723869_1	926562.Oweho_0802	2.25e-75	241.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia,2PBD5@246874|Cryomorphaceae	976|Bacteroidetes	P	STAS domain	ychM	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_256211_1	1172190.M947_08250	1.22e-21	93.2	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2YMQ8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_256211_2	1121438.JNJA01000010_gene1999	0.000188	44.7	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MGB8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_1271307_1	1137281.D778_00754	0.0	1029.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_1271307_2	745718.JADT01000008_gene3080	2.11e-47	153.0	COG4281@1|root,COG4281@2|Bacteria,4NSPP@976|Bacteroidetes,1I42A@117743|Flavobacteriia	976|Bacteroidetes	I	Acyl CoA binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ACBP
k59_1271307_3	641526.ADIWIN_1794	3.24e-17	77.8	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1HXNW@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_141248_1	637905.SVI_2371	1.71e-71	234.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,2Q9C1@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c45100	ThiC-associated,ThiC_Rad_SAM
k59_1781194_1	1565129.JSFF01000001_gene1020	3.5e-48	156.0	2EF5N@1|root,338YT@2|Bacteria,1NDPH@1224|Proteobacteria,1SEUB@1236|Gammaproteobacteria,2QCDB@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3718)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3718
k59_650706_1	680198.SCAB_6251	0.000184	45.4	COG1366@1|root,COG1366@2|Bacteria,2IR28@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
k59_86055_2	983544.Lacal_1655	2.53e-102	300.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1HXZT@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_481636_1	411154.GFO_2694	5.11e-70	228.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_1498341_1	1353276.JADR01000007_gene1305	7.34e-21	90.5	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_1498341_2	1123037.AUDE01000028_gene2954	1.5e-32	116.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1HYHU@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_141268_1	1121931.AUHG01000016_gene1040	3.56e-232	658.0	COG0495@1|root,COG0495@2|Bacteria,4PKSC@976|Bacteroidetes,1IJEG@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
k59_367026_1	649349.Lbys_0832	1.18e-16	82.8	COG2972@1|root,COG2972@2|Bacteria,4NH51@976|Bacteroidetes,47MBJ@768503|Cytophagia	976|Bacteroidetes	T	regulator of cell autolysis	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_367026_2	1443665.JACA01000005_gene487	1.9e-11	63.5	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,1HZ0N@117743|Flavobacteriia,2YI5Z@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_1781226_1	316407.1799937	6.45e-28	103.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,3XPIY@561|Escherichia	1236|Gammaproteobacteria	C	It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055	NifU_N
k59_1781226_2	392500.Swoo_1778	6.97e-68	206.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,2QBXM@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564	-	ko:K05997,ko:K13628	-	-	-	-	ko00000,ko03016	-	-	iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053	Fe-S_biosyn
k59_593513_1	1178825.ALIH01000003_gene2094	5.24e-202	567.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_1553023_1	944546.ABED_0292	7.21e-119	358.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2YNNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
k59_1045657_1	1178825.ALIH01000002_gene914	6.18e-30	110.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia	976|Bacteroidetes	O	general stress protein	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
k59_1157779_1	929558.SMGD1_2207	8.08e-44	149.0	COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,42WHD@68525|delta/epsilon subdivisions,2YQ36@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1157779_2	929558.SMGD1_2208	1.47e-55	185.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,42MCZ@68525|delta/epsilon subdivisions,2YNV4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	HlyD_3
k59_311751_1	1121931.AUHG01000016_gene1067	4.78e-13	67.4	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1HXY3@117743|Flavobacteriia	976|Bacteroidetes	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
k59_311751_2	411154.GFO_0793	2.91e-235	650.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1HX8P@117743|Flavobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
k59_311751_3	411154.GFO_0792	1.43e-18	79.7	2CC77@1|root,32S0M@2|Bacteria,4NS9F@976|Bacteroidetes,1I3Y8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
k59_1553044_1	592029.DDD_1250	1.67e-38	140.0	2A9C6@1|root,30YH7@2|Bacteria,4NU52@976|Bacteroidetes,1I2KI@117743|Flavobacteriia,3HK7F@363408|Nonlabens	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
k59_1781270_1	1137281.D778_02444	8.12e-187	548.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
k59_199199_1	1121931.AUHG01000010_gene801	3.76e-14	70.9	28IIT@1|root,2Z8JU@2|Bacteria,4NJ1B@976|Bacteroidetes,1HYC7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_199199_2	1121931.AUHG01000010_gene800	9.26e-86	260.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1I0JC@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_311769_1	425104.Ssed_3819	5.99e-65	201.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,2QBRC@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_876254_1	1123228.AUIH01000022_gene3091	3.8e-48	170.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales	135619|Oceanospirillales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_1332448_1	572480.Arnit_1956	1.21e-21	91.3	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2YMTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k59_1332448_2	572480.Arnit_1957	6.03e-78	244.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2YM7M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_986860_1	62928.azo1686	9.53e-41	142.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KUCN@206389|Rhodocyclales	206389|Rhodocyclales	EG	Solute carrier family 35	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_986860_2	1123367.C666_10070	1.63e-83	254.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,2KVI8@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
k59_653373_1	1172190.M947_08155	8.17e-117	343.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_143932_1	1281779.H009_18618	1.39e-16	73.9	2E3Y8@1|root,32YVA@2|Bacteria,1NAMJ@1224|Proteobacteria,2UF7H@28211|Alphaproteobacteria,4BH6Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2945)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2945
k59_1783820_1	1414720.CBYM010000003_gene371	4.68e-18	91.7	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Y_Y_Y
k59_986871_1	1178825.ALIH01000001_gene2502	4.05e-112	327.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1HXDH@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_986871_2	1046627.BZARG_1726	4e-59	194.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_484189_1	1121931.AUHG01000019_gene3016	2.05e-102	311.0	COG3281@1|root,COG3281@2|Bacteria,4PMAP@976|Bacteroidetes,1HZME@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH
k59_30120_1	326298.Suden_1812	8.65e-29	111.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2YMKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_30120_2	929558.SMGD1_1671	8.69e-81	246.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2YMJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_823874_1	1341181.FLJC2902T_09410	3.69e-29	106.0	COG3592@1|root,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,1I5MP@117743|Flavobacteriia,2NX8J@237|Flavobacterium	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
k59_934137_1	90814.KL370891_gene1166	2.83e-57	191.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,4603A@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_934137_2	452638.Pnec_0317	2.74e-29	115.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,1K195@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_30138_1	1537917.JU82_00240	1.51e-15	71.2	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2YQ4A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_30138_2	563040.Saut_0199	4.21e-161	454.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2YMH9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_30138_3	563040.Saut_0198	1.27e-109	323.0	COG0794@1|root,COG2905@1|root,COG0794@2|Bacteria,COG2905@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_1726477_1	944547.ABLL_2349	8.11e-36	139.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,43BQW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,dCache_1
k59_369738_1	1121931.AUHG01000010_gene532	3.53e-144	407.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1HWZN@117743|Flavobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_986916_1	1121931.AUHG01000010_gene803	3.11e-09	56.6	COG0596@1|root,COG0596@2|Bacteria,4NEY1@976|Bacteroidetes,1HY77@117743|Flavobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_986916_2	1121931.AUHG01000010_gene804	8.35e-85	256.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.30,1.1.1.401	ko:K00019,ko:K21883	ko00051,ko00072,ko00650,ko01100,ko01120,map00051,map00072,map00650,map01100,map01120	M00088	R01361,R11339	RC00089,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k59_1208334_1	620914.JH621246_gene2772	8.19e-07	52.4	COG2197@1|root,COG2197@2|Bacteria,4P1FH@976|Bacteroidetes,1I7EI@117743|Flavobacteriia	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_934150_1	1178825.ALIH01000008_gene808	4.2e-91	289.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1HXGI@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_1386137_1	1172190.M947_08870	1.51e-49	168.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,42R3P@68525|delta/epsilon subdivisions,2YPBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COGs COG2829 Outer membrane phospholipase A	-	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_1386137_2	1172190.M947_04795	0.00011	43.5	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_1103742_1	929558.SMGD1_2805	2.98e-85	261.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,43BHX@68525|delta/epsilon subdivisions,2YMEI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_712197_1	572480.Arnit_1350	1.02e-106	331.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2YM8G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_1614980_1	13616.ENSMODP00000026937	4.86e-125	363.0	COG1845@1|root,KOG4664@2759|Eukaryota,39ASV@33154|Opisthokonta,3BF9J@33208|Metazoa,3CUZX@33213|Bilateria,488M1@7711|Chordata,499D3@7742|Vertebrata,3JFS4@40674|Mammalia,4K95F@9263|Metatheria	33208|Metazoa	C	Subunits I, II and III form the functional core of the enzyme complex	COX3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0008150,GO:0008535,GO:0009987,GO:0016020,GO:0016043,GO:0017004,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045277,GO:0065003,GO:0070069,GO:0070469,GO:0071840,GO:0098796,GO:0098803	-	ko:K02262	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX3
k59_653471_1	504487.JCM19302_2452	9e-78	235.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_258835_1	367737.Abu_1266	1.78e-100	303.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2YMPB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Glycerol-3-phosphate dehydrogenase	glpC	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_17,Fer4_7,Fer4_8
k59_1726532_1	1353529.M899_0903	4.55e-46	160.0	COG0598@1|root,COG0598@2|Bacteria,1NWUN@1224|Proteobacteria,42S8K@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	CorA-like Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_30191_1	1565129.JSFF01000008_gene2662	1.43e-135	397.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,2Q9YV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	butA	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
k59_1442887_2	945713.IALB_2752	1.47e-36	134.0	COG0482@1|root,COG0482@2|Bacteria	2|Bacteria	J	sulfurtransferase activity	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_1726558_1	572480.Arnit_1662	1.09e-32	128.0	COG0745@1|root,COG0745@2|Bacteria,1R0ZN@1224|Proteobacteria,43D45@68525|delta/epsilon subdivisions	572480.Arnit_1662|-	KT	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_878856_1	1121931.AUHG01000011_gene1636	7.94e-74	241.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1274004_1	85643.Tmz1t_0805	2.04e-10	60.1	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,2KV4W@206389|Rhodocyclales	206389|Rhodocyclales	I	AcyL-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_1274004_2	748247.AZKH_4269	1.3e-84	255.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_369859_1	1123228.AUIH01000036_gene2823	4.74e-86	259.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1XHVI@135619|Oceanospirillales	135619|Oceanospirillales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_484346_1	1178825.ALIH01000011_gene54	1.3e-90	283.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia	976|Bacteroidetes	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_1726597_2	504487.JCM19302_4048	8.24e-25	94.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_1726597_3	1178825.ALIH01000009_gene1339	3.02e-60	191.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1726597_4	504487.JCM19302_4046	4.93e-46	153.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_144108_1	1137281.D778_02596	1.6e-43	148.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
k59_144108_2	1137281.D778_02597	4.75e-68	212.0	COG2227@1|root,COG2227@2|Bacteria,4PNUQ@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_765417_1	1121931.AUHG01000017_gene1489	2.7e-142	407.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1HYXA@117743|Flavobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_765417_2	1121931.AUHG01000017_gene1488	4.86e-07	49.7	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1I17Y@117743|Flavobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_427373_1	1380600.AUYN01000001_gene2511	3.45e-97	284.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,1I23X@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	yjgM	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_427373_2	1380600.AUYN01000001_gene2513	9.44e-170	480.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_484385_2	373903.Hore_13640	2.37e-23	95.5	COG2074@1|root,COG2074@2|Bacteria,1UJSS@1239|Firmicutes,25F96@186801|Clostridia	186801|Clostridia	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1501261_1	572480.Arnit_0663	7.7e-07	50.1	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1501261_2	572480.Arnit_0662	1.12e-89	282.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2YNBS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_224447_2	326298.Suden_2006	2.21e-21	90.9	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2YN53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP1418	MurB_C
k59_1464943_1	317025.Tcr_0443	1.37e-49	169.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,45ZRM@72273|Thiotrichales	72273|Thiotrichales	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_1464943_2	1123517.JOMR01000001_gene1590	8.03e-37	128.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,460T1@72273|Thiotrichales	72273|Thiotrichales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_953287_1	1168067.JAGP01000001_gene555	1.26e-108	344.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,462IM@72273|Thiotrichales	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_337840_1	1380600.AUYN01000009_gene1299	3.29e-79	250.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_1071947_1	190486.XAC3994	1.37e-07	58.5	COG4585@1|root,COG4585@2|Bacteria,1R6FX@1224|Proteobacteria,1S0UD@1236|Gammaproteobacteria,1X45P@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
k59_620122_1	525244.HMPREF0023_1202	6.94e-112	331.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,3NKGE@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Type II/IV secretion system protein	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_1581061_1	1178825.ALIH01000001_gene2320	1.46e-20	93.2	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia	976|Bacteroidetes	N	Cell envelope biogenesis protein OmpA	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1468416_1	313603.FB2170_14943	3.14e-26	107.0	COG1629@1|root,COG4771@2|Bacteria,4NFKZ@976|Bacteroidetes,1HY23@117743|Flavobacteriia,2PI68@252356|Maribacter	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1468416_2	1123278.KB893559_gene2984	3.48e-34	130.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47K8M@768503|Cytophagia	976|Bacteroidetes	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_1013544_1	1197477.IA57_10275	2.44e-222	629.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1409640_1	1231057.AMGD01000066_gene1119	4.1e-11	68.6	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HBC2@91061|Bacilli,26EKD@186818|Planococcaceae	91061|Bacilli	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,dCache_1
k59_1581092_2	1476902.A0A067ZI88_9CAUD	3.08e-35	125.0	4QFEY@10239|Viruses,4QQTN@28883|Caudovirales	28883|Caudovirales	S	Phage P2 GpU	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1581092_3	572547.Amico_1108	3.39e-39	139.0	COG4540@1|root,COG4540@2|Bacteria,3TBNJ@508458|Synergistetes	508458|Synergistetes	S	Baseplate assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
k59_1581092_4	1476902.A0A067ZG47_9CAUD	5e-97	297.0	4QC7J@10239|Viruses,4R007@35237|dsDNA viruses  no RNA stage,4QSEV@28883|Caudovirales,4QJU7@10662|Myoviridae	10662|Myoviridae	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_846687_1	945713.IALB_2197	2.19e-56	193.0	COG0587@1|root,COG0587@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1468437_1	1123518.ARWI01000001_gene726	7.09e-132	382.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,461JD@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1633760_1	1121931.AUHG01000012_gene2534	3.33e-167	508.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1232847_2	1123228.AUIH01000002_gene1477	8.63e-73	226.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XHGU@135619|Oceanospirillales	135619|Oceanospirillales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_1072026_1	945713.IALB_0934	2.55e-35	120.0	COG0361@1|root,COG0361@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_1072026_2	552811.Dehly_1072	1.08e-18	80.5	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi,34DBP@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_564376_1	1442598.JABW01000013_gene2181	1.73e-14	72.8	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2YNPW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_564376_2	929558.SMGD1_0400	6.29e-21	92.8	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2YRBR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_9,dCache_3
k59_564390_1	929558.SMGD1_0664	9.17e-100	300.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2YMR3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_1468510_1	1123518.ARWI01000001_gene1115	1.72e-47	164.0	COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,1RZEP@1236|Gammaproteobacteria,461N1@72273|Thiotrichales	72273|Thiotrichales	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
k59_1633819_1	323850.Shew_2581	9.14e-104	320.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,2Q9ZC@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M3A and M3B, thimet oligopeptidase F	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_1232915_1	1380600.AUYN01000001_gene2223	3.08e-61	195.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1HWV1@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
k59_1232915_2	1380600.AUYN01000001_gene2224	8.4e-57	179.0	2AI4E@1|root,318IH@2|Bacteria,4NQNN@976|Bacteroidetes,1I2SE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_620273_1	273121.WS1869	6.64e-14	77.4	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,42TBG@68525|delta/epsilon subdivisions,2YPER@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k59_620286_1	980584.AFPB01000162_gene2205	3.2e-52	178.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia,406PH@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_620286_2	1178825.ALIH01000006_gene1397	2.88e-18	78.6	2C3S9@1|root,33H9U@2|Bacteria,4NXWR@976|Bacteroidetes,1I6E6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_620286_3	504487.JCM19302_2972	1.54e-08	54.3	COG0494@1|root,COG0494@2|Bacteria,4NHER@976|Bacteroidetes,1HWUJ@117743|Flavobacteriia	976|Bacteroidetes	L	GDP-mannose pyrophosphatase	nudK	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_1013686_2	883.DvMF_2131	1.34e-29	113.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,2M9NY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_564459_1	411154.GFO_0743	5.93e-187	528.0	COG0025@1|root,COG0025@2|Bacteria,4NF54@976|Bacteroidetes,1HYT6@117743|Flavobacteriia	976|Bacteroidetes	P	sodium proton antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
k59_846820_1	504487.JCM19302_3382	8.08e-194	545.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_846820_2	504487.JCM19302_3383	2.2e-67	208.0	299NP@1|root,2ZWR1@2|Bacteria,4NP8Q@976|Bacteroidetes,1I269@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54268_1	929558.SMGD1_2698	7.16e-06	46.2	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2YPEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k59_54268_2	563040.Saut_1147	1.46e-58	187.0	2A2WP@1|root,30RAU@2|Bacteria,1PMAH@1224|Proteobacteria,42Y3T@68525|delta/epsilon subdivisions,2YQRJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LptC
k59_846851_1	323850.Shew_3360	6.25e-17	73.6	2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,2QCVX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3012
k59_955853_1	323850.Shew_1737	1.55e-112	327.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,2QA05@267890|Shewanellaceae	1236|Gammaproteobacteria	H	TIGRFAM nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
k59_955853_2	318167.Sfri_1527	2.12e-47	152.0	2E5J4@1|root,330AE@2|Bacteria,1N67S@1224|Proteobacteria,1S8TV@1236|Gammaproteobacteria,2QC7N@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ykof
k59_955853_3	225849.swp_2907	2e-26	106.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,2Q91E@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_620341_1	1121931.AUHG01000010_gene49	1.74e-62	194.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1I3Z8@117743|Flavobacteriia	976|Bacteroidetes	J	chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_620341_2	1121931.AUHG01000010_gene50	3.3e-08	53.5	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,1HYEB@117743|Flavobacteriia	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,DUF4301
k59_846856_1	1121931.AUHG01000010_gene773	2.35e-164	488.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_281032_1	326298.Suden_0215	5.87e-65	204.0	COG0433@1|root,COG0433@2|Bacteria,1Q4H7@1224|Proteobacteria,42Z6M@68525|delta/epsilon subdivisions,2YR7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_281032_2	563040.Saut_0196	6.09e-118	352.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2YN5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_955872_1	1380600.AUYN01000007_gene3318	1.62e-162	472.0	COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,1HXFH@117743|Flavobacteriia	976|Bacteroidetes	S	SPFH Band 7 PHB domain protein	yqiK	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
k59_955872_2	745718.JADT01000020_gene305	7.89e-87	260.0	29F7N@1|root,3025B@2|Bacteria,4NNR8@976|Bacteroidetes,1I26I@117743|Flavobacteriia	976|Bacteroidetes	S	serine protease	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
k59_955872_3	391587.KAOT1_14917	4.12e-57	188.0	COG0304@1|root,COG0304@2|Bacteria,4NGJD@976|Bacteroidetes,1HYKN@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_846909_3	1123518.ARWI01000001_gene177	3.76e-106	311.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,460TE@72273|Thiotrichales	72273|Thiotrichales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k59_846909_4	1123517.JOMR01000001_gene1162	1.46e-15	70.9	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,460YP@72273|Thiotrichales	72273|Thiotrichales	S	PFAM YCII-related	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k59_1233074_1	1121931.AUHG01000010_gene24	1.01e-113	360.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k59_1581353_2	313603.FB2170_07919	1.07e-93	288.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1HYK2@117743|Flavobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_564617_1	1122225.AULQ01000006_gene945	1.29e-79	246.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_846972_1	411154.GFO_0784	5.19e-35	127.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1HX8A@117743|Flavobacteriia	976|Bacteroidetes	S	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
k59_846972_2	411154.GFO_0783	2.21e-65	221.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_54358_1	1121931.AUHG01000017_gene1509	6.39e-116	355.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k59_1409972_1	458817.Shal_3382	1.97e-55	191.0	COG0484@1|root,COG0484@2|Bacteria,1N89W@1224|Proteobacteria,1SDS5@1236|Gammaproteobacteria,2QDDR@267890|Shewanellaceae	1236|Gammaproteobacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1072225_1	655815.ZPR_3134	1.05e-137	399.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1HYDV@117743|Flavobacteriia	976|Bacteroidetes	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1013920_1	563040.Saut_0318	7.54e-123	385.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1233167_1	1026882.MAMP_01259	8.74e-05	47.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,461IM@72273|Thiotrichales	72273|Thiotrichales	T	response regulator	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg,SBP_bac_3
k59_1634032_1	1123518.ARWI01000001_gene402	6.43e-99	298.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1RY9Y@1236|Gammaproteobacteria,4622H@72273|Thiotrichales	72273|Thiotrichales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_54434_2	472759.Nhal_1114	1.33e-46	161.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1S059@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_54448_1	1172190.M947_10125	9.09e-47	162.0	COG3642@1|root,COG3642@2|Bacteria,1NSBH@1224|Proteobacteria,42Q7Z@68525|delta/epsilon subdivisions,2YN3B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	lipopolysaccharide core region biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54448_2	929558.SMGD1_1955	4.17e-44	150.0	COG3907@1|root,COG3907@2|Bacteria,1QV68@1224|Proteobacteria,42V5Q@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Acid phosphatase homologues	-	-	-	ko:K12978	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PAP2
k59_564801_1	411154.GFO_3505	1.21e-30	117.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1HYIU@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
k59_564801_2	411154.GFO_3506	9.61e-52	174.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1HY6A@117743|Flavobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_1634086_1	641491.DND132_2901	1.87e-40	147.0	COG3437@1|root,COG3437@2|Bacteria,1NDRJ@1224|Proteobacteria,42TDX@68525|delta/epsilon subdivisions,2WV2R@28221|Deltaproteobacteria,2M9V2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_564823_1	1122599.AUGR01000004_gene2128	1.97e-25	112.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XIJY@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS_3,PAS_4
k59_847207_1	391615.ABSJ01000050_gene1158	4.89e-72	228.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1J4N9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_281316_1	929558.SMGD1_1263	8.64e-37	132.0	COG0242@1|root,COG0242@2|Bacteria,1QNIH@1224|Proteobacteria,42TAD@68525|delta/epsilon subdivisions,2YPKH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	COG0242 N-formylmethionyl-tRNA deformylase	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
k59_281316_2	598467.BrE312_4156	6.99e-26	107.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k59_1014181_1	929558.SMGD1_0804	6.11e-108	324.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2YNJC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1014182_1	572480.Arnit_0609	4.52e-08	52.8	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,42MTC@68525|delta/epsilon subdivisions,2YMSX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cosR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1014182_2	572480.Arnit_0608	1.83e-112	335.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ5@1224|Proteobacteria,42NJC@68525|delta/epsilon subdivisions,2YMGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	cosS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_1410265_1	998674.ATTE01000001_gene1113	2.69e-10	61.2	28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3360
k59_54534_1	1163398.AJJP01000209_gene3031	5.32e-13	77.0	28ICC@1|root,2Z8ER@2|Bacteria,1MWES@1224|Proteobacteria,1RSKN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54548_1	113395.AXAI01000011_gene6533	3.29e-16	78.2	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_973941_1	1123037.AUDE01000029_gene1531	3.94e-73	226.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_973941_2	1121875.KB907547_gene3382	0.0	1531.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_1598790_1	1537917.JU82_05485	1.55e-137	397.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2YMD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_411933_1	225849.swp_1211	5.03e-115	347.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,2QB4Z@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_973946_1	1452718.JBOY01000145_gene616	6.11e-08	53.5	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1RZYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	branched-chain amino acid	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
k59_299001_2	926551.KB900703_gene923	2.5e-261	774.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HX4D@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_1598812_1	326298.Suden_1168	5.02e-88	269.0	2C76X@1|root,2ZM1W@2|Bacteria,1P5JD@1224|Proteobacteria,42P9T@68525|delta/epsilon subdivisions,2YMRC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_638205_1	323850.Shew_0102	2.06e-09	56.2	2EFSX@1|root,339IW@2|Bacteria,1NG97@1224|Proteobacteria,1SGWE@1236|Gammaproteobacteria,2QD2W@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2986)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2986
k59_73451_1	1379858.N508_01849	4.3e-35	136.0	COG1807@1|root,COG1807@2|Bacteria,2GGAM@200930|Deferribacteres	200930|Deferribacteres	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_186594_1	362418.IW19_23630	2.6e-59	199.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2NV4W@237|Flavobacterium	976|Bacteroidetes	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
k59_186594_2	349163.Acry_1196	6.85e-57	185.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2U7RR@28211|Alphaproteobacteria,2JY9B@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
k59_973985_2	709032.Sulku_0175	4.08e-69	224.0	COG1450@1|root,COG1450@2|Bacteria,1N6HF@1224|Proteobacteria,42XAQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	NU	Belongs to the GSP D family	-	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	OmpA,Secretin
k59_807692_1	563040.Saut_0318	2.4e-129	403.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1371129_1	929558.SMGD1_1743	6.68e-162	466.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_1428193_2	1347342.BN863_11150	1.74e-13	70.9	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1HY6E@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_1711406_1	90814.KL370891_gene863	3.63e-141	407.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,461E9@72273|Thiotrichales	72273|Thiotrichales	GK	ROK family	-	-	2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
k59_186609_1	62928.azo0524	6.97e-47	151.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VW4D@28216|Betaproteobacteria,2KX5U@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_186609_2	62928.azo0523	1.48e-93	287.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,2VJBQ@28216|Betaproteobacteria,2KV00@206389|Rhodocyclales	206389|Rhodocyclales	C	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k59_1316627_1	1121931.AUHG01000011_gene1751	5.31e-85	261.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_1371146_1	1347342.BN863_32350	2.46e-30	115.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1HYA2@117743|Flavobacteriia	976|Bacteroidetes	EG	of the drug metabolite transporter (DMT) superfamily	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1371146_2	1046627.BZARG_509	3.64e-30	110.0	2AV2W@1|root,31KST@2|Bacteria,4NRSK@976|Bacteroidetes,1I39E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
k59_863661_1	1121931.AUHG01000011_gene2067	5.98e-163	459.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1HY7B@117743|Flavobacteriia	976|Bacteroidetes	N	flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_1145247_1	1250278.JQNQ01000001_gene3232	1.97e-113	339.0	COG1633@1|root,COG1633@2|Bacteria,4NFAU@976|Bacteroidetes	976|Bacteroidetes	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1198093_1	1123518.ARWI01000001_gene490	1.22e-39	134.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_1198093_2	317025.Tcr_1338	1.13e-117	339.0	COG0662@1|root,COG1476@1|root,COG0662@2|Bacteria,COG1476@2|Bacteria,1QYXN@1224|Proteobacteria,1T3X7@1236|Gammaproteobacteria,463UT@72273|Thiotrichales	72273|Thiotrichales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k59_1198093_3	1123518.ARWI01000001_gene1673	6.91e-127	363.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,460EA@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_1198093_4	90814.KL370892_gene1952	1.44e-75	234.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,461MS@72273|Thiotrichales	72273|Thiotrichales	G	PFAM Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_1654971_1	1380600.AUYN01000007_gene3178	5.27e-13	67.8	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1654971_2	1121912.AUHD01000003_gene3099	1.5e-117	341.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1HXMN@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_1654971_3	1137281.D778_01776	3.34e-57	182.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1I55E@117743|Flavobacteriia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
k59_1654971_4	1380600.AUYN01000007_gene3176	4.02e-145	417.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1HXA2@117743|Flavobacteriia	976|Bacteroidetes	E	ABC transporter	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_1654971_5	1178825.ALIH01000003_gene2207	2.48e-159	466.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl endopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_974015_1	929558.SMGD1_1211	5.13e-133	380.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2YMEM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_974015_2	563040.Saut_2133	4.38e-61	191.0	COG0352@1|root,COG0352@2|Bacteria,1P3Q4@1224|Proteobacteria,42SIF@68525|delta/epsilon subdivisions,2YPJ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine-phosphate diphosphorylase activity	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_974015_3	929558.SMGD1_1213	3.6e-87	262.0	COG4106@1|root,COG4106@2|Bacteria,1QZ2S@1224|Proteobacteria,43CEU@68525|delta/epsilon subdivisions,2YTCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Methyltransferase domain	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
k59_807745_1	1123326.JFBL01000022_gene2618	1.24e-18	84.7	COG0778@1|root,COG0778@2|Bacteria,1Q0G9@1224|Proteobacteria,42QDE@68525|delta/epsilon subdivisions,2YMPN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_807745_2	1172190.M947_09295	1.39e-16	79.3	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2YNEQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Membrane-bound lytic murein transglycosylase C	mltC	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k59_354766_1	1123518.ARWI01000001_gene974	1.75e-131	388.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1485420_1	1123514.KB905902_gene238	4.69e-226	644.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,45ZUR@72273|Thiotrichales	72273|Thiotrichales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k59_1198102_1	945713.IALB_0477	1.2e-73	236.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1088705_1	1268240.ATFI01000001_gene2789	4.68e-44	161.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,2FMHS@200643|Bacteroidia,4ANCA@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	susA	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
k59_186650_1	886377.Murru_1946	3.3e-46	165.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
k59_186650_2	504487.JCM19302_3736	1.33e-25	98.6	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k59_1485426_1	1123518.ARWI01000001_gene998	1.17e-84	276.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1768164_1	1249480.B649_06535	3.56e-138	403.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2YNPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Nitrogenase protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_1768164_2	990073.ATHU01000001_gene1788	5.36e-37	129.0	2BS4Z@1|root,32M5X@2|Bacteria,1Q34G@1224|Proteobacteria,42WRS@68525|delta/epsilon subdivisions,2YQC8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1088706_1	90813.JQMT01000001_gene1725	2.59e-12	73.6	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
k59_1371191_1	1380600.AUYN01000006_gene793	9.6e-177	500.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1HYJS@117743|Flavobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_1711480_2	1121931.AUHG01000010_gene157	5.84e-78	243.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_129196_1	1397528.Q671_09300	4.46e-64	220.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,dCache_1
k59_1033302_2	1123518.ARWI01000001_gene1242	2.04e-71	238.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_9
k59_186689_1	1249975.JQLP01000008_gene355	5.43e-95	292.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,1HXIY@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_524820_1	748247.AZKH_0529	2.26e-106	323.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KV73@206389|Rhodocyclales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1316721_1	1137281.D778_01505	8.09e-286	787.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_807806_1	317025.Tcr_1924	1.88e-138	426.0	COG0642@1|root,COG2972@1|root,COG3437@1|root,COG3829@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1T3XA@1236|Gammaproteobacteria,461JT@72273|Thiotrichales	72273|Thiotrichales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_750442_1	641526.ADIWIN_0218	1.18e-140	429.0	COG2771@1|root,COG3292@1|root,COG2771@2|Bacteria,COG3292@2|Bacteria,4PKBX@976|Bacteroidetes,1HWMG@117743|Flavobacteriia	976|Bacteroidetes	KT	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_524838_1	1123518.ARWI01000001_gene171	1.52e-174	506.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,45ZS9@72273|Thiotrichales	72273|Thiotrichales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_581609_1	1178825.ALIH01000004_gene2950	2.51e-19	85.9	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_581609_2	1392490.JHZX01000001_gene2364	1.03e-36	130.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
k59_1768254_1	945713.IALB_0213	2.55e-55	185.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pimB_1	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_1428326_1	1265503.KB905171_gene547	1.01e-69	228.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,2Q5XV@267889|Colwelliaceae	1236|Gammaproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
k59_186746_1	90814.KL370891_gene867	2.95e-162	459.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,4600R@72273|Thiotrichales	72273|Thiotrichales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1316771_1	1123514.KB905899_gene1746	3.03e-112	340.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,45ZU1@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1258898_1	90814.KL370891_gene1753	8.74e-27	104.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,45ZR7@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k59_1258898_2	90813.JQMT01000001_gene375	4.31e-50	168.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,46103@72273|Thiotrichales	72273|Thiotrichales	S	protein conserved in bacteria	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
k59_807863_1	388413.ALPR1_08598	7.14e-61	194.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,47P7F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_581640_1	1380600.AUYN01000006_gene314	3.99e-130	381.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_1371299_1	1355374.JARU01000006_gene1739	9.17e-43	154.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,42N6Q@68525|delta/epsilon subdivisions,2YMZC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_1371299_2	944547.ABLL_1945	1.59e-29	115.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,43BTT@68525|delta/epsilon subdivisions,2YTGQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_638379_1	1121931.AUHG01000011_gene1678	3.74e-114	349.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1HWZF@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
k59_638379_2	926559.JoomaDRAFT_2870	0.0	956.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_354878_1	1123228.AUIH01000069_gene2634	1.64e-74	249.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1XN5H@135619|Oceanospirillales	135619|Oceanospirillales	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_299221_1	1168067.JAGP01000001_gene557	1.14e-141	421.0	COG0835@1|root,COG0835@2|Bacteria,1QVCF@1224|Proteobacteria,1RYBW@1236|Gammaproteobacteria,461VX@72273|Thiotrichales	72273|Thiotrichales	NT	PFAM CheW domain protein	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k59_1485543_1	746697.Aeqsu_0500	3.1e-108	318.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,1HZG0@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k59_1485543_2	1178825.ALIH01000008_gene759	5.02e-60	195.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_1316790_1	1123514.KB905899_gene580	7.35e-64	206.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1316790_2	1123518.ARWI01000001_gene2163	1.99e-79	239.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,460FA@72273|Thiotrichales	72273|Thiotrichales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k59_919893_1	326298.Suden_0027	6.12e-54	173.0	2AIZZ@1|root,319I0@2|Bacteria,1Q2U7@1224|Proteobacteria,42W9A@68525|delta/epsilon subdivisions,2YQB5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_807884_1	983544.Lacal_2175	4.25e-67	214.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_752206_2	1537917.JU82_01040	2.65e-11	62.8	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2YMHX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Membrane protease subunits	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_188601_1	1565314.OA34_05800	4.11e-39	140.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2YTP3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_583345_1	1380600.AUYN01000009_gene1795	6.98e-107	311.0	COG0494@1|root,COG0494@2|Bacteria,4PKI3@976|Bacteroidetes,1IJ9T@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_131006_1	90814.KL370891_gene263	7.15e-102	320.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1542616_1	411154.GFO_2980	1.31e-103	310.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1090547_1	1265503.KB905160_gene2855	2.85e-11	72.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k59_471004_1	1121931.AUHG01000010_gene87	1.3e-107	312.0	2E7W0@1|root,332AS@2|Bacteria,4NPQ3@976|Bacteroidetes,1I2EB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1672928_1	1380600.AUYN01000006_gene480	4.14e-151	437.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia	976|Bacteroidetes	M	probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
k59_1672928_2	1380600.AUYN01000006_gene479	1.52e-77	243.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1HZ5W@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_1617778_1	1453505.JASY01000037_gene3907	1.28e-42	159.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2NSFC@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1786441_1	563040.Saut_0289	3.52e-74	223.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2YP8H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_32741_1	62928.azo3578	1.78e-120	353.0	COG0438@1|root,COG0438@2|Bacteria,1QIXJ@1224|Proteobacteria,2VKFD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_881601_1	768066.HELO_2643	8.06e-68	212.0	28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein-protein 5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146752_2	189425.PGRAT_28290	7.65e-35	140.0	COG0642@1|root,COG2205@2|Bacteria,1U78N@1239|Firmicutes,4HFCP@91061|Bacilli,27742@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	ETR2	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_1163523_1	1168067.JAGP01000001_gene216	8.23e-145	414.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,45ZXX@72273|Thiotrichales	72273|Thiotrichales	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_1050309_1	1121931.AUHG01000017_gene1536	6.8e-140	399.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_32779_2	391603.FBALC1_00405	6.13e-42	142.0	2BY49@1|root,32U9Y@2|Bacteria,4NSER@976|Bacteroidetes,1I4B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32779_3	1120951.AUBG01000015_gene3430	1.67e-10	58.2	2EFZ5@1|root,339RB@2|Bacteria,4NXH9@976|Bacteroidetes	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_1335464_2	391603.FBALC1_04257	2.82e-22	90.9	2DSUM@1|root,33HGR@2|Bacteria,4PMCB@976|Bacteroidetes,1IMTF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1729330_1	1511.CLOST_0761	7.51e-06	53.5	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25SUT@186804|Peptostreptococcaceae	186801|Clostridia	NT	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PilJ,sCache_3_3
k59_1210122_1	90814.KL370891_gene1063	1.58e-47	158.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,4603F@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1504084_1	1449063.JMLS01000038_gene959	7.37e-42	142.0	COG3832@1|root,COG3832@2|Bacteria,1VSD6@1239|Firmicutes,4HV03@91061|Bacilli,26XTD@186822|Paenibacillaceae	91061|Bacilli	V	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_1504084_2	945713.IALB_3104	3.92e-14	71.6	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yoaV3	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1389074_1	702438.HMPREF9431_01705	5.23e-08	56.2	COG2076@1|root,COG2076@2|Bacteria,4PNIU@976|Bacteroidetes,2G0YS@200643|Bacteroidia	976|Bacteroidetes	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_32795_1	1336233.JAEH01000016_gene2977	9.56e-16	75.9	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,2QAID@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_430094_1	1121931.AUHG01000011_gene1768	8.62e-72	219.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_430094_2	411154.GFO_2753	1.23e-33	129.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase M14	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k59_146806_1	1121931.AUHG01000011_gene2045	7.04e-137	393.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,1HY4I@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_146806_2	1121931.AUHG01000011_gene2043	1.99e-85	263.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
k59_1558446_1	1453505.JASY01000027_gene426	3.03e-31	127.0	COG2911@1|root,COG2911@2|Bacteria,4PKAY@976|Bacteroidetes,1IJ62@117743|Flavobacteriia,2P0JD@237|Flavobacterium	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1389089_1	471874.PROSTU_00561	3.26e-58	194.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,3Z7GW@586|Providencia	1236|Gammaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440	Ala_racemase_C,Ala_racemase_N
k59_317409_1	458817.Shal_1233	1.91e-168	496.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,2Q8IB@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_881692_1	1121931.AUHG01000010_gene142	5.78e-103	318.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_91578_1	1123037.AUDE01000027_gene2097	9.66e-169	497.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXUG@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
k59_881700_1	329726.AM1_2723	5.38e-47	154.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_881700_2	1238450.VIBNISOn1_1160062	2.96e-27	103.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N_3
k59_826939_2	572480.Arnit_0171	1.4e-87	263.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2YMYB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_1106691_1	1046627.BZARG_2271	2.23e-93	293.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1786565_1	985053.VMUT_1086	3.6e-13	73.6	COG0500@1|root,arCOG01402@2157|Archaea	2157|Archaea	Q	TIGRFAM methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_1558498_1	1046627.BZARG_1929	1.88e-57	198.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_1558498_2	1197477.IA57_03260	3.67e-117	345.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
k59_826961_1	1191523.MROS_1001	3.55e-35	131.0	COG0486@1|root,COG0486@2|Bacteria	2|Bacteria	S	GTPase activity	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_372562_1	1250278.JQNQ01000001_gene2821	2.5e-89	276.0	COG4222@1|root,COG4222@2|Bacteria,4NHE8@976|Bacteroidetes,1HZ39@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_372562_2	1197477.IA57_02975	1.51e-06	49.7	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1HX4S@117743|Flavobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k59_936594_1	317025.Tcr_1184	1.34e-23	99.4	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,45ZVZ@72273|Thiotrichales	72273|Thiotrichales	P	inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k59_936594_2	1123518.ARWI01000001_gene238	1.47e-74	231.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,45ZR0@72273|Thiotrichales	72273|Thiotrichales	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1106736_1	945550.VISI1226_19002	1.61e-20	90.1	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XU10@135623|Vibrionales	135623|Vibrionales	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_1106736_2	406818.XBJ1_2845	8.6e-89	277.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH dehydrogenase	ndh	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_2051,iPC815.YPO1617	Pyr_redox_2
k59_826985_1	693979.Bache_R0042	4.77e-129	395.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,4AK8A@815|Bacteroidaceae	976|Bacteroidetes	G	glycosyl hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_204669_1	411154.GFO_2050	4.57e-76	238.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1HWWN@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_204669_2	1121931.AUHG01000011_gene2317	4.14e-115	362.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,1HYFE@117743|Flavobacteriia	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos,ShlB
k59_1163688_1	1123517.JOMR01000001_gene271	4.16e-45	166.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,463V7@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_715272_1	1123518.ARWI01000001_gene2003	1.01e-34	119.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	VL23_05015	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
k59_715272_2	1123518.ARWI01000001_gene2002	3.13e-122	354.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,4603P@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_936615_1	1250005.PHEL85_1440	1.74e-80	266.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1HYB0@117743|Flavobacteriia,3VVXK@52959|Polaribacter	976|Bacteroidetes	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_936615_2	1178825.ALIH01000003_gene2091	2.8e-11	63.2	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1HWNF@117743|Flavobacteriia	976|Bacteroidetes	E	NADPH-dependent glutamate synthase beta chain and related	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_1617971_1	1123518.ARWI01000001_gene964	7.43e-94	293.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,45ZWF@72273|Thiotrichales	72273|Thiotrichales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_1729464_1	90814.KL370891_gene138	2.56e-82	259.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,46033@72273|Thiotrichales	72273|Thiotrichales	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,OEP
k59_1729464_2	1123514.KB905899_gene1906	4.07e-112	343.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_204675_1	1123517.JOMR01000001_gene1697	1.83e-09	58.2	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,460N2@72273|Thiotrichales	72273|Thiotrichales	S	Permease YjgP YjgQ	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_204675_2	1123514.KB905899_gene1646	2.3e-92	276.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,460F1@72273|Thiotrichales	72273|Thiotrichales	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k59_1558565_1	1111732.AZOD01000021_gene643	1.33e-17	81.3	2DBIX@1|root,2Z9HE@2|Bacteria,1NT20@1224|Proteobacteria,1RZMW@1236|Gammaproteobacteria,1X4U2@135614|Xanthomonadales	135614|Xanthomonadales	S	CRISPR-associated protein (Cas_Csy2)	-	-	-	ko:K19128	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csy2
k59_989953_2	1150621.SMUL_1052	3.28e-25	101.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2YP5K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	protein-glutamate methylesterase	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
k59_1448398_1	1380600.AUYN01000009_gene2056	4.12e-189	548.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_1732165_1	929558.SMGD1_1976	4.17e-93	274.0	COG3216@1|root,COG3216@2|Bacteria,1PSZW@1224|Proteobacteria,42SRF@68525|delta/epsilon subdivisions,2YPQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_829684_2	572480.Arnit_0860	2.66e-43	155.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42QY3@68525|delta/epsilon subdivisions,2YNZ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_2,sCache_2
k59_1507038_1	411154.GFO_0359	1.91e-108	328.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HX4R@117743|Flavobacteriia	976|Bacteroidetes	P	arylsulfatase a	atsA_1	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
k59_718027_1	563040.Saut_0946	3.11e-33	125.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2YMC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_718027_2	563040.Saut_0945	1.52e-71	219.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,42SCS@68525|delta/epsilon subdivisions,2YPIF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_1338400_1	563040.Saut_0866	5.96e-60	193.0	COG3267@1|root,COG3267@2|Bacteria,1QUIM@1224|Proteobacteria,42NAC@68525|delta/epsilon subdivisions,2YNHY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	ATPase (AAA	-	-	4.3.3.7	ko:K01714,ko:K12283	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	AAA_22
k59_1338400_2	1249480.B649_08745	2.91e-27	112.0	COG0457@1|root,COG0457@2|Bacteria,1Q60C@1224|Proteobacteria,42X29@68525|delta/epsilon subdivisions,2YQQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3
k59_1338400_3	929558.SMGD1_2292	3.49e-38	132.0	COG1619@1|root,COG1619@2|Bacteria,1Q23R@1224|Proteobacteria,42UXX@68525|delta/epsilon subdivisions,2YPD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1212401_1	1137281.D778_02826	5.62e-39	147.0	COG2374@1|root,COG2374@2|Bacteria,4NKW3@976|Bacteroidetes,1I0VD@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	LTD
k59_1109576_1	929558.SMGD1_0338	5.45e-43	140.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2YPX8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Cold-shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1109576_2	1123518.ARWI01000001_gene1712	1.38e-15	80.9	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K18968,ko:K21085	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko02000	9.B.34.1.2	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,MASE2
k59_375288_1	340177.Cag_1820	7.8e-49	164.0	2C91Z@1|root,337JM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1052667_1	1178825.ALIH01000006_gene1457	1.65e-47	160.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,1HY29@117743|Flavobacteriia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
k59_1052667_2	865937.Gilli_3482	5.97e-117	347.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1I0Z6@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_489760_1	572480.Arnit_0020	5.39e-80	237.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2YP5I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_489760_2	572480.Arnit_0018	6.63e-60	192.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,42SUN@68525|delta/epsilon subdivisions	1224|Proteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1675907_1	411154.GFO_2846	1.55e-14	72.4	COG4206@1|root,COG4774@1|root,COG4206@2|Bacteria,COG4774@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1392008_1	572480.Arnit_1793	1.57e-75	246.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YR6J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1212440_1	944546.ABED_2014	4.33e-74	242.0	COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,42NGV@68525|delta/epsilon subdivisions,2YR74@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mu transposase, C-terminal	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,Mu-transpos_C,rve
k59_35732_1	1172190.M947_10255	1.23e-93	296.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2YMSQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
k59_829753_2	1056820.KB900643_gene814	4.28e-54	173.0	COG0517@1|root,COG0517@2|Bacteria,1QZHE@1224|Proteobacteria,1T471@1236|Gammaproteobacteria,2PPNP@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_320336_2	1123518.ARWI01000001_gene299	9.97e-59	197.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1212441_1	425104.Ssed_3475	2.62e-71	229.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,2Q90F@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590	CN_hydrolase
k59_770878_1	1380600.AUYN01000007_gene3324	8.48e-117	337.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,1HZ59@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k59_1279754_1	1437824.BN940_08691	3.28e-77	248.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,3T2S3@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_395187_2	317025.Tcr_1227	3.37e-52	172.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,1RRVB@1236|Gammaproteobacteria,460I4@72273|Thiotrichales	72273|Thiotrichales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
k59_845800_1	313612.L8106_21734	7.43e-21	96.7	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1G2A0@1117|Cyanobacteria,1H8JI@1150|Oscillatoriales	1117|Cyanobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_9,Response_reg
k59_845801_1	313596.RB2501_05645	4.5e-16	81.3	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
k59_280245_1	1537917.JU82_00195	6.39e-67	224.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YNQA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_1012632_1	90814.KL370891_gene689	5.46e-32	115.0	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria	1224|Proteobacteria	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k59_1012632_2	317025.Tcr_1449	2.48e-233	668.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,460Z0@72273|Thiotrichales	72273|Thiotrichales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k59_955030_1	929558.SMGD1_1636	3.19e-104	313.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2YMF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_619299_2	1137281.D778_00062	1.9e-30	113.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_619306_2	945713.IALB_2604	7.54e-48	163.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1129492_1	1121438.JNJA01000011_gene1812	3.81e-09	57.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42NN5@68525|delta/epsilon subdivisions,2X266@28221|Deltaproteobacteria,2MBDX@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_1467555_1	944547.ABLL_0636	1.12e-49	174.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_1467555_2	367737.Abu_0497	8.95e-22	89.7	COG0847@1|root,COG0847@2|Bacteria,1P0GY@1224|Proteobacteria,42RBT@68525|delta/epsilon subdivisions,2YNWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	dna polymerase iii	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_845845_2	1380600.AUYN01000009_gene1767	3.91e-120	350.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
k59_845845_3	1380600.AUYN01000009_gene1768	1.21e-179	508.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1HXRQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
k59_451881_2	1137281.D778_02472	8.27e-164	467.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_451881_3	1178825.ALIH01000008_gene750	5.25e-102	300.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,1HXEZ@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_395286_1	62928.azo1908	1.15e-103	307.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,2KU95@206389|Rhodocyclales	206389|Rhodocyclales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_1467596_1	1123514.KB905899_gene935	2.57e-68	211.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,460W6@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k59_1467596_2	90814.KL370891_gene1148	2.01e-16	83.6	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,46035@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_619373_1	755732.Fluta_2885	9.76e-24	108.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_845898_1	1380600.AUYN01000009_gene1354	0.0	960.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1HX8K@117743|Flavobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_845898_2	1178825.ALIH01000011_gene36	2.77e-53	167.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_1232052_1	317025.Tcr_1550	1.12e-145	445.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,45ZSY@72273|Thiotrichales	72273|Thiotrichales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_1409008_1	411154.GFO_2703	5.7e-186	518.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1HXXW@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_563564_1	1380600.AUYN01000009_gene1195	3.26e-234	654.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_903536_1	85643.Tmz1t_3841	5.82e-70	221.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_1071509_1	1123514.KB905899_gene1624	2.14e-49	173.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS_3,PAS_4,Protoglobin
k59_1232097_1	1168034.FH5T_02645	1.4e-57	189.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,2FMUU@200643|Bacteroidia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wcfX	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_1232097_2	944547.ABLL_2295	4.6e-16	76.6	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1012818_1	1182590.BN5_03271	2.91e-30	111.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1YFT1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k59_1012818_2	1123228.AUIH01000002_gene1455	2.23e-81	249.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1XHEY@135619|Oceanospirillales	135619|Oceanospirillales	P	transporter	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_1633317_1	572480.Arnit_1895	3.03e-142	411.0	COG4865@1|root,COG4865@2|Bacteria,1PCBW@1224|Proteobacteria,42PTY@68525|delta/epsilon subdivisions,2YMYF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Methylaspartate mutase	-	-	5.4.99.1	ko:K19268	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_asp_mut_E
k59_168690_1	929558.SMGD1_0408	2.26e-10	67.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2YRCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
k59_1696778_1	90814.KL370891_gene1026	3.98e-58	192.0	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,1RPIZ@1236|Gammaproteobacteria,460KR@72273|Thiotrichales	72273|Thiotrichales	E	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k59_1696778_2	1328313.DS2_18688	2.94e-07	49.7	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	2.8.1.10	ko:K03149,ko:K03154	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	iAF1260.b4407,iBWG_1329.BWG_3651,iECDH10B_1368.ECDH10B_4180,iECDH1ME8569_1439.ECDH1ME8569_3851,iECDH1ME8569_1439.EcDH1_4003,iEcDH1_1363.EcDH1_4003,iEcolC_1368.EcolC_4034,iJO1366.b4407,iJR904.b4407,iUMNK88_1353.UMNK88_4832,iY75_1357.Y75_RS17090	ThiS
k59_1244353_1	289376.THEYE_A0738	2.05e-80	248.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_340774_1	326427.Cagg_1377	2.19e-06	49.3	COG0270@1|root,COG0270@2|Bacteria	2|Bacteria	L	DNA (cytosine-5-)-methyltransferase activity	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k59_340774_2	862971.SANR_0871	1.72e-13	75.1	COG0323@1|root,COG0323@2|Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_3,Hypoth_Ymh
k59_567050_1	90814.KL370891_gene1763	6.35e-33	125.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,45ZT2@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1583832_2	717773.Thicy_0177	4.85e-137	396.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,45ZSV@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_171769_1	929558.SMGD1_1655	1.48e-80	244.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2YP68@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_1696795_1	411154.GFO_0776	4.28e-189	532.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_1640493_1	717772.THIAE_10110	3.67e-35	129.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,461Q2@72273|Thiotrichales	72273|Thiotrichales	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	-	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k59_1640493_2	1123518.ARWI01000001_gene1184	4.41e-140	400.0	COG0730@1|root,COG0730@2|Bacteria,1MVBS@1224|Proteobacteria,1S62V@1236|Gammaproteobacteria,463IN@72273|Thiotrichales	72273|Thiotrichales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_454220_1	1217718.ALOU01000013_gene338	2.06e-16	80.5	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,1JZWZ@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	wspR	-	2.7.7.65	ko:K11444	ko02020,ko02025,map02020,map02025	M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,HATPase_c,Response_reg
k59_454220_2	90814.KL370892_gene2125	1.14e-98	289.0	29WJN@1|root,30I61@2|Bacteria,1NR09@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_454220_3	1123514.KB905899_gene618	2.82e-46	151.0	COG0460@1|root,COG0460@2|Bacteria,1NFDV@1224|Proteobacteria,1SHR9@1236|Gammaproteobacteria,463ET@72273|Thiotrichales	72273|Thiotrichales	E	homoserine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_848868_1	1123514.KB905899_gene2028	1.04e-23	97.1	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,1SZRM@1236|Gammaproteobacteria,460HH@72273|Thiotrichales	72273|Thiotrichales	S	Molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_848868_2	1123518.ARWI01000001_gene1301	5.18e-65	209.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,46026@72273|Thiotrichales	72273|Thiotrichales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_623663_1	497321.C664_02860	1.54e-69	214.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,2KWAR@206389|Rhodocyclales	206389|Rhodocyclales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_171775_1	1280692.AUJL01000005_gene1655	3.44e-28	119.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,36DR0@31979|Clostridiaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k59_171775_2	1123326.JFBL01000011_gene213	1.77e-71	219.0	COG1406@1|root,COG1406@2|Bacteria,1NFHA@1224|Proteobacteria,42WKA@68525|delta/epsilon subdivisions,2YSDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k59_171775_3	1123326.JFBL01000011_gene214	2.79e-64	198.0	COG2201@1|root,COG2201@2|Bacteria,1QZ2G@1224|Proteobacteria,43CEJ@68525|delta/epsilon subdivisions,2YQ1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_58803_1	1123518.ARWI01000001_gene158	3.36e-232	647.0	COG0460@1|root,COG4492@1|root,COG0460@2|Bacteria,COG4492@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,45ZV6@72273|Thiotrichales	72273|Thiotrichales	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_58803_2	1123517.JOMR01000001_gene1038	6.87e-75	238.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,460QB@72273|Thiotrichales	72273|Thiotrichales	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k59_1470327_1	411154.GFO_1000	5.38e-56	182.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1470327_2	411154.GFO_0999	8.23e-36	133.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1HXIV@117743|Flavobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_1188503_1	1123518.ARWI01000001_gene475	4.2e-120	357.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,461JZ@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_340820_1	1380600.AUYN01000001_gene2476	2.08e-160	459.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_340820_2	865937.Gilli_3553	1.48e-15	71.2	COG4818@1|root,COG4818@2|Bacteria,4NUVP@976|Bacteroidetes,1I44F@117743|Flavobacteriia,2P6Y9@244698|Gillisia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1188508_1	323850.Shew_3555	7.55e-20	86.3	COG3608@1|root,COG3608@2|Bacteria,1QUH0@1224|Proteobacteria,1RUQ0@1236|Gammaproteobacteria,2Q8WC@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k59_1188508_2	323850.Shew_3554	1.29e-14	72.4	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,2QAG5@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM glutamine synthetase catalytic region	glnA	GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1244405_1	332101.JIBU02000013_gene1271	6.2e-60	194.0	COG2120@1|root,COG2120@2|Bacteria,1UZDV@1239|Firmicutes,24FCK@186801|Clostridia,36IHP@31979|Clostridiaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_1470345_1	1392498.JQLH01000001_gene3126	1.6e-125	367.0	COG4916@1|root,COG4916@2|Bacteria,4PPBH@976|Bacteroidetes	976|Bacteroidetes	V	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_1753386_1	1123057.P872_14445	2.13e-39	148.0	COG0223@1|root,COG0223@2|Bacteria,4NUJG@976|Bacteroidetes,47UEJ@768503|Cytophagia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
k59_1414519_1	1123514.KB905899_gene1440	1.08e-135	394.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,460K3@72273|Thiotrichales	72273|Thiotrichales	T	PAS domain	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k59_1414519_2	1123514.KB905899_gene1439	2.72e-228	637.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZZ6@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1640558_1	504487.JCM19302_3947	6.39e-121	351.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1HWWV@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_1640558_2	1121007.AUML01000001_gene1317	4.71e-23	92.4	COG1510@1|root,COG1510@2|Bacteria,4NSVR@976|Bacteroidetes,1I1BX@117743|Flavobacteriia	976|Bacteroidetes	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115351_1	1453505.JASY01000002_gene3095	5.54e-69	232.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia,2NSSK@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1301649_2	1410668.JNKC01000006_gene690	8.67e-07	58.2	COG2197@1|root,COG2197@2|Bacteria,1V0AE@1239|Firmicutes,25K0Z@186801|Clostridia,36NYJ@31979|Clostridiaceae	186801|Clostridia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_962492_1	317025.Tcr_0841	4.08e-126	375.0	COG0288@1|root,COG0288@2|Bacteria,1QYIQ@1224|Proteobacteria,1T3X3@1236|Gammaproteobacteria,463UR@72273|Thiotrichales	72273|Thiotrichales	P	Carboxysome Shell Carbonic Anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
k59_962492_2	1168067.JAGP01000001_gene123	1.38e-16	78.6	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,460IM@72273|Thiotrichales	72273|Thiotrichales	S	Carboxysome shell peptide mid-region	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
k59_1640573_1	1538644.KO02_08600	2.08e-63	205.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1IQ0E@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_1696873_1	1188252.AJYK01000070_gene2153	1.31e-133	388.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XVS8@135623|Vibrionales	135623|Vibrionales	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_1301660_1	1041826.FCOL_09575	0.0	1424.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,4NJ3U@976|Bacteroidetes,1HZWJ@117743|Flavobacteriia,2NXRP@237|Flavobacterium	976|Bacteroidetes	L	Pfam:Methyltransf_26	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
k59_1132116_1	1380600.AUYN01000001_gene2696	2.86e-144	420.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
k59_1132116_2	1178825.ALIH01000012_gene1796	9.09e-35	129.0	COG0160@1|root,COG0160@2|Bacteria,4PM70@976|Bacteroidetes,1IJJZ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD1	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_1753430_1	1123517.JOMR01000001_gene74	2.65e-19	82.0	2DXTC@1|root,346FM@2|Bacteria,1P1WH@1224|Proteobacteria,1SRK3@1236|Gammaproteobacteria,4630J@72273|Thiotrichales	72273|Thiotrichales	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k59_1753430_2	1123514.KB905900_gene2248	3.82e-56	183.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,4618N@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	KorB,ParBc
k59_906263_1	1172190.M947_04680	6.88e-68	228.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2YMJY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
k59_1074975_1	1349785.BAUG01000005_gene471	0.0	1043.0	COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,1HWWZ@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_918617_1	1121931.AUHG01000012_gene2612	2.43e-175	536.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWPC@117743|Flavobacteriia	976|Bacteroidetes	M	Cell envelope biogenesis protein AsmA	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_353568_1	929558.SMGD1_2574	1.1e-66	207.0	COG1381@1|root,COG1381@2|Bacteria,1QAJR@1224|Proteobacteria,42NUJ@68525|delta/epsilon subdivisions,2YPCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RecO N terminal	-	-	-	-	-	-	-	-	-	-	-	-	RecO_N_2
k59_973068_1	1380600.AUYN01000007_gene3108	3.68e-138	405.0	COG0664@1|root,COG0664@2|Bacteria,4NEWA@976|Bacteroidetes,1HWPV@117743|Flavobacteriia	976|Bacteroidetes	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1427051_1	572480.Arnit_0834	1.78e-22	94.7	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42M7C@68525|delta/epsilon subdivisions,2YTS2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1427051_2	1123326.JFBL01000002_gene1603	5.13e-48	162.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2YR33@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_580381_1	1000565.METUNv1_01937	4.17e-67	225.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	mcrA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_1032104_1	1278309.KB907100_gene1840	2.55e-107	323.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XIDM@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_1484189_1	1380600.AUYN01000001_gene2926	2.17e-44	147.0	COG0454@1|root,COG0456@2|Bacteria,4NQ7Z@976|Bacteroidetes,1I2SH@117743|Flavobacteriia	976|Bacteroidetes	K	(GNAT) family	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_1484189_2	1353276.JADR01000001_gene41	1.13e-33	124.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1HXU5@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
k59_1032117_1	572480.Arnit_0404	1.32e-98	298.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,42PB4@68525|delta/epsilon subdivisions,2YNJ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15576	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
k59_1370003_1	1054213.HMPREF9946_05266	1.13e-57	201.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2TRS4@28211|Alphaproteobacteria,2JQTC@204441|Rhodospirillales	204441|Rhodospirillales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
k59_694148_1	1123518.ARWI01000001_gene2021	2.8e-51	190.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,460QS@72273|Thiotrichales	72273|Thiotrichales	S	TIGRFAM TIGR02099 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_973085_1	1380600.AUYN01000001_gene2272	4.26e-117	345.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_694160_2	1123514.KB905899_gene838	9.45e-107	331.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,460V7@72273|Thiotrichales	72273|Thiotrichales	T	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
k59_467764_1	929558.SMGD1_2695	4.96e-87	260.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2YP3U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_467764_2	929558.SMGD1_2694	5.22e-47	155.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2YPNW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	acetyltransferase	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k59_1144191_1	563040.Saut_2046	8.31e-49	167.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Major Facilitator Superfamily	MA20_25070	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_694185_1	1270193.JARP01000003_gene2089	1.15e-89	281.0	COG0702@1|root,COG0702@2|Bacteria,4NG5U@976|Bacteroidetes,1I0T9@117743|Flavobacteriia,2NT3H@237|Flavobacterium	976|Bacteroidetes	GM	Carbohydrate-binding protein SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_297944_1	504487.JCM19302_2312	1.15e-50	172.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1HY15@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
k59_297944_2	1380600.AUYN01000006_gene348	3.14e-164	496.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k59_918699_1	572480.Arnit_0589	1.23e-82	253.0	COG0547@1|root,COG0547@2|Bacteria,1PZRF@1224|Proteobacteria,42R0S@68525|delta/epsilon subdivisions,2YNX2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Glycosyl transferase family, helical bundle domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_1317244_2	572480.Arnit_2662	4.28e-58	181.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2YQEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_74151_1	1121931.AUHG01000011_gene2238	1.49e-195	545.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1HWWG@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_1371750_1	1380600.AUYN01000009_gene1729	3.47e-49	164.0	COG3209@1|root,COG3209@2|Bacteria,4NNQE@976|Bacteroidetes,1I2G4@117743|Flavobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1371750_3	1380600.AUYN01000009_gene1728	5.4e-85	253.0	2CCRG@1|root,30F34@2|Bacteria,4NP6P@976|Bacteroidetes,1I2CY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1655571_1	588596.U9TV30	1.16e-18	83.2	COG1131@1|root,KOG0059@2759|Eukaryota,38BPG@33154|Opisthokonta	33154|Opisthokonta	I	ATPase activity, coupled to transmembrane movement of substances	-	-	-	ko:K05644	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.211	-	-	ABC2_membrane_3,ABC_tran
k59_1655571_2	1298593.TOL_2675	5.55e-153	432.0	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1XHSJ@135619|Oceanospirillales	135619|Oceanospirillales	S	ABC transporter ATP-binding	livG	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
k59_1655571_3	1209072.ALBT01000046_gene2586	1.52e-70	224.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,1RMAZ@1236|Gammaproteobacteria,1FG5V@10|Cellvibrio	1236|Gammaproteobacteria	E	Branched-chain amino acid transport system / permease component	fmdF	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_1428803_2	318161.Sden_3001	1.02e-33	121.0	COG3628@1|root,COG3628@2|Bacteria,1N23A@1224|Proteobacteria,1SCDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
k59_355348_2	563040.Saut_1640	6.1e-112	342.0	COG1262@1|root,COG1352@1|root,COG1262@2|Bacteria,COG1352@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2YNCE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_31
k59_974485_1	1178825.ALIH01000002_gene1093	5.11e-45	150.0	COG3911@1|root,COG3911@2|Bacteria,4NNT6@976|Bacteroidetes,1I25D@117743|Flavobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k59_1259392_1	411154.GFO_3225	4.62e-81	245.0	COG1587@1|root,COG1587@2|Bacteria,4NNSC@976|Bacteroidetes,1I2TT@117743|Flavobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_1259392_2	411154.GFO_3226	1.11e-98	294.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1HY0P@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_638856_1	1137281.D778_02544	8.24e-93	288.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_243709_1	572480.Arnit_1129	9.74e-71	228.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_243709_2	572480.Arnit_1128	1.19e-27	108.0	COG0683@1|root,COG0683@2|Bacteria,1Q7JN@1224|Proteobacteria,42NDA@68525|delta/epsilon subdivisions,2YN6T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_355353_1	1380600.AUYN01000009_gene1534	5.33e-91	285.0	COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,1HZCD@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_355353_2	504487.JCM19302_2273	2.55e-23	95.1	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1HX5H@117743|Flavobacteriia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_525365_1	1172190.M947_03040	6.05e-47	164.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2YMSR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_1033848_1	323850.Shew_1538	1.65e-28	104.0	COG2841@1|root,COG2841@2|Bacteria,1NDHE@1224|Proteobacteria,1SDIQ@1236|Gammaproteobacteria,2QCNM@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	VPA0402	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
k59_469593_1	1392488.JHZY01000004_gene2113	0.0	906.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1HY04@117743|Flavobacteriia,2XI13@283735|Leeuwenhoekiella	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_469593_2	1286632.P278_01590	1.15e-61	189.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1I2VK@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_469593_3	983544.Lacal_0411	3.58e-43	145.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1HXHF@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_243723_1	90814.KL370891_gene45	1.8e-142	408.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,460AH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_243723_2	90814.KL370891_gene44	2.38e-220	612.0	COG2010@1|root,COG2010@2|Bacteria,1QVK1@1224|Proteobacteria,1RYEK@1236|Gammaproteobacteria,4621F@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
k59_243723_3	317025.Tcr_0156	6.17e-134	389.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,461KA@72273|Thiotrichales	72273|Thiotrichales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_1317287_1	392500.Swoo_1312	7.22e-58	187.0	COG2971@1|root,COG2971@2|Bacteria,1R41I@1224|Proteobacteria,1RPMK@1236|Gammaproteobacteria,2Q9ZH@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM ATPase, BadF BadG BcrA BcrD type	gspK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931	2.7.1.8	ko:K18676	ko00520,ko01100,map00520,map01100	-	R01961	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	BcrAD_BadFG
k59_129791_1	1353528.DT23_14180	3.18e-98	292.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria,2XM21@285107|Thioclava	28211|Alphaproteobacteria	EG	EamA-like transporter family	MA20_19820	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1599550_2	326298.Suden_0401	3.96e-109	318.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2YM9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_1089314_1	1392498.JQLH01000001_gene2168	7.22e-22	90.9	COG0462@1|root,COG0462@2|Bacteria,4NGWV@976|Bacteroidetes,1HZ79@117743|Flavobacteriia	976|Bacteroidetes	EF	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
k59_1655626_1	1122225.AULQ01000004_gene2168	8.15e-87	263.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1HXCX@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_1655626_2	1380600.AUYN01000003_gene211	9.88e-269	739.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1HWJT@117743|Flavobacteriia	976|Bacteroidetes	C	acetyl-CoA hydrolase	cat2	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_1655626_3	1347342.BN863_5060	4.86e-19	81.3	COG0647@1|root,COG0647@2|Bacteria,4NQ45@976|Bacteroidetes,1IJW5@117743|Flavobacteriia	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1259438_1	391603.FBALC1_07138	1.16e-70	214.0	COG2346@1|root,COG2346@2|Bacteria,4NQZD@976|Bacteroidetes,1I341@117743|Flavobacteriia	976|Bacteroidetes	S	COG2346 Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_1259438_2	1178825.ALIH01000005_gene219	9.96e-245	705.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia	976|Bacteroidetes	O	cytochrome c biogenesis	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_1371819_1	1565129.JSFF01000021_gene605	1.28e-06	49.7	2EIRS@1|root,33CH5@2|Bacteria,1NKZ1@1224|Proteobacteria,1SJ2M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_16285_1	1380600.AUYN01000003_gene12	2.22e-189	532.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1HXB7@117743|Flavobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_582147_1	1165841.SULAR_07770	9.02e-93	290.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,42P71@68525|delta/epsilon subdivisions,2YNAA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_355423_1	493475.GARC_4312	1.08e-11	63.2	COG3644@1|root,COG3644@2|Bacteria,1RK12@1224|Proteobacteria,1SAPY@1236|Gammaproteobacteria,46B15@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2239)	-	-	-	ko:K09965	-	-	-	-	ko00000	-	-	-	DUF2239
k59_355423_2	493475.GARC_4313	1.39e-41	149.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Na driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k59_129835_1	869213.JCM21142_31105	3.23e-11	68.6	COG1502@1|root,COG1502@2|Bacteria,4NE2W@976|Bacteroidetes,47P06@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_974549_1	1237149.C900_05250	4.25e-26	107.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,47KMS@768503|Cytophagia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_751039_1	1123228.AUIH01000004_gene1049	6.82e-163	488.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHSH@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_582177_1	1123518.ARWI01000001_gene1186	5.82e-96	309.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales	72273|Thiotrichales	E	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_582177_2	1123514.KB905899_gene1944	4.53e-70	225.0	COG2199@1|root,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing a CheY-like receiver domain and a GGDEF domain	rrpX	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_1371855_1	1178825.ALIH01000011_gene15	4.88e-49	172.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1371855_2	1380600.AUYN01000009_gene1334	2.68e-98	290.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_920422_1	398579.Spea_0140	5.11e-122	361.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,2QA4S@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k59_412730_2	1197477.IA57_06760	6e-137	397.0	COG5000@1|root,COG5000@2|Bacteria,4PKJN@976|Bacteroidetes,1IJB1@117743|Flavobacteriia	976|Bacteroidetes	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_920436_1	1169144.KB910971_gene2156	8.91e-12	70.5	COG1181@1|root,COG1181@2|Bacteria,1UINV@1239|Firmicutes,4ITZW@91061|Bacilli	91061|Bacilli	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
k59_1541471_1	543728.Vapar_1984	4.53e-60	209.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria,4AD3R@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMART alpha amylase catalytic sub domain	treY	-	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
k59_1317381_1	1244083.CSUNSWCD_508	2.73e-11	70.5	COG4191@1|root,COG4191@2|Bacteria,1PDXS@1224|Proteobacteria,42PCU@68525|delta/epsilon subdivisions,2YNP0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,dCache_1
k59_525478_1	857087.Metme_2046	3.03e-18	77.4	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,1SCCQ@1236|Gammaproteobacteria,1XFTW@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
k59_525478_2	1168067.JAGP01000001_gene1185	9.96e-89	266.0	COG2230@1|root,COG2230@2|Bacteria,1QVX6@1224|Proteobacteria,1T2MM@1236|Gammaproteobacteria,4628Q@72273|Thiotrichales	72273|Thiotrichales	M	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
k59_1486154_1	1283284.AZUK01000001_gene440	5.25e-38	145.0	COG2199@1|root,COG3614@1|root,COG2199@2|Bacteria,COG3614@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_696144_1	1484460.JSWG01000008_gene1959	8.13e-110	343.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_1198679_1	991.IW20_03690	3.62e-57	192.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1I3BR@117743|Flavobacteriia,2NYJF@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1198679_2	376686.Fjoh_3908	3.2e-89	271.0	COG1969@1|root,COG1969@2|Bacteria,4NIDY@976|Bacteroidetes	976|Bacteroidetes	C	TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_1371894_1	1484460.JSWG01000015_gene1232	4.86e-149	452.0	COG0308@1|root,COG0842@1|root,COG0308@2|Bacteria,COG0842@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k59_1486156_1	572480.Arnit_2949	5.9e-112	330.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2YMEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
k59_299860_1	944547.ABLL_0351	2.05e-46	156.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2YMKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_299860_2	572480.Arnit_2865	2.13e-74	231.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2YMX1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ABC transporter permease	nikY	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_638995_1	497321.C664_10707	6.25e-56	186.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2VHXC@28216|Betaproteobacteria,2KVPR@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_355489_1	323850.Shew_2128	1.94e-105	325.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,2Q9WF@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM transglutaminase domain protein	tgpA	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_1768914_1	1137281.D778_00420	2.99e-67	208.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,1IJMJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
k59_1768914_2	1380600.AUYN01000003_gene34	3.97e-14	66.6	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1I3WA@117743|Flavobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_485052_1	313594.PI23P_09160	3.11e-141	411.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia,3VVI9@52959|Polaribacter	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_713081_1	504487.JCM19302_262	2.79e-47	152.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1HYBW@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleoid-associated protein NdpA	-	-	-	-	-	-	-	-	-	-	-	-	NA37
k59_713081_2	1380600.AUYN01000006_gene337	2.86e-193	561.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,1HZ3X@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
k59_370592_1	929558.SMGD1_1788	1.86e-121	356.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_202588_2	387093.SUN_1735	6.81e-39	145.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2YNN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_370594_1	1123517.JOMR01000001_gene1398	3.03e-69	216.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,461ZM@72273|Thiotrichales	72273|Thiotrichales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_370594_2	317025.Tcr_0758	2.97e-08	54.3	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,461S9@72273|Thiotrichales	72273|Thiotrichales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_89503_1	1249997.JHZW01000003_gene3772	9.1e-146	432.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,1INAV@117743|Flavobacteriia,2PI0U@252356|Maribacter	976|Bacteroidetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_204682_1	1380600.AUYN01000010_gene910	5.73e-94	282.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1HWR2@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_204682_2	1178825.ALIH01000006_gene1413	1.06e-192	535.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,1HWQB@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_204682_3	641526.ADIWIN_3754	1.26e-92	275.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1050443_1	344747.PM8797T_07272	2.37e-22	101.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,2IZRQ@203682|Planctomycetes	203682|Planctomycetes	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD
k59_91694_1	572480.Arnit_0593	5.28e-134	382.0	COG0664@1|root,COG0664@2|Bacteria,1RIIE@1224|Proteobacteria,42T56@68525|delta/epsilon subdivisions,2YPFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_91694_2	944547.ABLL_0498	5.5e-32	119.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2YM8U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_1389239_1	1123228.AUIH01000022_gene3095	1.41e-94	307.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XHTM@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1504251_1	929558.SMGD1_0544	8.59e-132	394.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2YT9R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1673174_1	62928.azo2693	7.61e-56	187.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,2KWA3@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k59_1210277_1	1123367.C666_00625	7.2e-129	395.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,2KVJX@206389|Rhodocyclales	206389|Rhodocyclales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_1389269_1	694569.D7S_02404	4.57e-15	80.5	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,1Y7YT@135625|Pasteurellales	135625|Pasteurellales	P	Maltose transporter membrane protein	malF	-	-	ko:K10109	ko02010,map02010	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	BPD_transp_1,MalF_P2
k59_1558622_1	387093.SUN_1159	2.45e-39	138.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria,42TNP@68525|delta/epsilon subdivisions,2YTE8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k59_936671_1	411154.GFO_2163	1.99e-51	174.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k59_656565_1	1121931.AUHG01000011_gene1938	3.2e-125	368.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1HYIU@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
k59_1673200_1	1392498.JQLH01000001_gene1334	6.4e-98	291.0	28I9E@1|root,2Z8C2@2|Bacteria,4NFBW@976|Bacteroidetes,1HZK1@117743|Flavobacteriia	976|Bacteroidetes	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
k59_487166_1	1392498.JQLH01000001_gene2469	1.71e-48	166.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia,2PHZ7@252356|Maribacter	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_1335729_1	563040.Saut_1553	3.2e-55	187.0	28N6Q@1|root,2ZBBI@2|Bacteria,1R719@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_204749_1	929558.SMGD1_2524	4.5e-64	214.0	COG0488@1|root,COG0488@2|Bacteria,1QUVR@1224|Proteobacteria,42P66@68525|delta/epsilon subdivisions,2YRB1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_204749_2	759914.BP951000_0504	1e-17	85.9	COG1233@1|root,COG1233@2|Bacteria,2J838@203691|Spirochaetes	203691|Spirochaetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_261727_1	563040.Saut_2161	1.04e-31	116.0	COG1776@1|root,COG1776@2|Bacteria,1N49I@1224|Proteobacteria,42UKN@68525|delta/epsilon subdivisions,2YS4I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	COGs COG1776 Chemotaxis protein CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
k59_261727_2	563040.Saut_2162	1.04e-42	154.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43E1J@68525|delta/epsilon subdivisions,2YT3F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_261729_1	1178825.ALIH01000005_gene174	2.16e-99	305.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HWRN@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter, transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k59_1504317_1	1042377.AFPJ01000027_gene2658	4.31e-85	259.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,464E1@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the RimK family	rimK	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_1504317_2	323850.Shew_3665	9.94e-62	199.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,2Q8JC@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1673218_1	317025.Tcr_1800	1.62e-196	549.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,46262@72273|Thiotrichales	72273|Thiotrichales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k59_1673218_2	317025.Tcr_1801	4.07e-15	73.6	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,4616F@72273|Thiotrichales	72273|Thiotrichales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_542686_1	1123514.KB905899_gene984	1.88e-88	265.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_542686_2	90814.KL370891_gene1095	9.9e-140	403.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,45ZPI@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1673227_1	572480.Arnit_0220	4.22e-118	344.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2YMY0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_33032_1	455436.DS989813_gene996	1.64e-14	79.7	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,466B6@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_204764_1	94122.Shewana3_2415	4.18e-48	158.0	COG3045@1|root,COG3045@2|Bacteria,1RDI5@1224|Proteobacteria,1T060@1236|Gammaproteobacteria,2QBPY@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM CreA family protein	creA	-	-	ko:K05805	-	-	-	-	ko00000	-	-	-	CreA
k59_1729574_1	326298.Suden_1224	1.04e-109	324.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2YMYR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_487199_2	525898.Sdel_0952	1.23e-16	80.1	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
k59_91789_1	1157943.KB892705_gene2039	4.02e-78	248.0	COG3969@1|root,COG3969@2|Bacteria,2H4MT@201174|Actinobacteria	201174|Actinobacteria	S	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
k59_1445824_1	1279015.KB908460_gene2913	2.41e-91	295.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1Y3TQ@135624|Aeromonadales	135624|Aeromonadales	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_1618125_1	1380600.AUYN01000009_gene987	3.39e-25	99.4	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k59_1618125_2	1484460.JSWG01000004_gene2664	2.75e-71	228.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
k59_881935_1	317025.Tcr_0422	4.88e-99	317.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1RZB9@1236|Gammaproteobacteria,461VV@72273|Thiotrichales	72273|Thiotrichales	P	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
k59_1163885_2	1408164.MOLA814_01248	2.37e-30	116.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria	1224|Proteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
k59_204844_1	929558.SMGD1_2816	8.05e-76	241.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,42Q5Y@68525|delta/epsilon subdivisions,2YNT8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_147118_2	1380600.AUYN01000001_gene2359	2.09e-82	265.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_430422_1	990073.ATHU01000001_gene846	4.38e-45	155.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2YME6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	UDP-N-acetylglucosamine 4,6-dehydratase	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
k59_430422_2	1355368.JART01000025_gene61	3.1e-81	251.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2YMNH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.92	ko:K15895	ko00520,map00520	-	R09825	RC00006,RC00781	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_1389417_1	1217720.ALOX01000053_gene1584	6.4e-82	268.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQY7@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_990136_1	1415754.JQMK01000002_gene3030	7.28e-49	169.0	COG4782@1|root,COG4782@2|Bacteria,1REVW@1224|Proteobacteria,1S55K@1236|Gammaproteobacteria,468W1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_1210414_1	1123267.JONN01000001_gene2304	6.33e-28	114.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_1445918_1	768671.ThimaDRAFT_0630	1.08e-43	146.0	COG3385@1|root,COG3385@2|Bacteria,1QN0E@1224|Proteobacteria,1TKBX@1236|Gammaproteobacteria,1X1PH@135613|Chromatiales	135613|Chromatiales	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_881999_1	1453501.JELR01000001_gene2715	7.95e-05	48.9	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,465GC@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k59_881999_2	1239962.C943_04007	3.08e-13	69.7	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_936785_1	563040.Saut_1863	2.58e-150	436.0	COG3203@1|root,COG3203@2|Bacteria,1QZ2N@1224|Proteobacteria,42QVI@68525|delta/epsilon subdivisions,2YP28@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_261864_1	983544.Lacal_1679	3.41e-89	274.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_1729705_2	1191523.MROS_0806	5.29e-36	123.0	COG2088@1|root,COG2088@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
k59_147183_1	563040.Saut_0369	4.52e-107	315.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_598671_1	317025.Tcr_0950	9.73e-181	549.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1558835_1	411154.GFO_1824	1.41e-146	424.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
k59_1786911_1	929558.SMGD1_0138	7.75e-90	286.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2YMAI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1729744_1	929558.SMGD1_0782	2.37e-19	84.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_1729744_2	1172190.M947_06725	1.94e-26	99.0	COG1551@1|root,COG1551@2|Bacteria,1Q4KC@1224|Proteobacteria,42W0C@68525|delta/epsilon subdivisions,2YQ7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the CsrA family	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k59_1729744_3	929558.SMGD1_0784	9.98e-47	157.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2YM85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_N
k59_487359_1	1232410.KI421424_gene1786	1.46e-79	258.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,43T8B@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG-1	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3349	Fer2_4,Fer4_10,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_487359_2	1121918.ARWE01000001_gene284	4.95e-38	140.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,43T0W@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF-1	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_204940_1	317025.Tcr_0933	6.35e-64	203.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria,46128@72273|Thiotrichales	72273|Thiotrichales	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_204940_2	1123518.ARWI01000001_gene1731	0.0	935.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1163990_1	563040.Saut_0068	1.93e-64	226.0	COG1352@1|root,COG2201@1|root,COG3290@1|root,COG5000@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3290@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43CSM@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	CheR methyltransferase, SAM binding domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,PAS,PAS_10,PAS_9
k59_1163998_1	90813.JQMT01000001_gene671	2.93e-65	216.0	COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria,462J4@72273|Thiotrichales	72273|Thiotrichales	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_1210496_1	1123228.AUIH01000026_gene3879	3.71e-84	258.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XHXX@135619|Oceanospirillales	135619|Oceanospirillales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_1618290_1	143224.JQMD01000002_gene3005	2.03e-101	304.0	COG0665@1|root,COG0665@2|Bacteria,4NFPQ@976|Bacteroidetes,1HX5D@117743|Flavobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase TIGR03364	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1618290_2	1392498.JQLH01000001_gene933	7.41e-100	296.0	COG0546@1|root,COG0546@2|Bacteria,4NHWM@976|Bacteroidetes,1I1GY@117743|Flavobacteriia,2PHYF@252356|Maribacter	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1618290_3	143224.JQMD01000002_gene3007	1.13e-105	308.0	COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,4NN23@976|Bacteroidetes,1I1NN@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k59_1618290_4	1235803.C825_00697	8.46e-34	133.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,2G065@200643|Bacteroidia,231BY@171551|Porphyromonadaceae	976|Bacteroidetes	H	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_715616_1	929558.SMGD1_0444	7.45e-104	319.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2YN4X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k59_715616_2	929558.SMGD1_0445	2.95e-28	112.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2YN7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_1786961_1	411154.GFO_2151	1.3e-100	308.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_1335987_2	1123326.JFBL01000017_gene2329	5.9e-51	177.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2YMIX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k59_1729800_2	1453505.JASY01000008_gene705	4.84e-11	64.3	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1729800_3	1453505.JASY01000008_gene705	6.06e-12	65.1	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_1050684_1	1348657.M622_15070	2.47e-61	200.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,2KV6F@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_487412_1	326298.Suden_2002	1.23e-113	333.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2YN4V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_1729803_1	754436.JCM19237_4361	3.58e-77	245.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XSNZ@135623|Vibrionales	135623|Vibrionales	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_286057_1	1380600.AUYN01000003_gene58	9.39e-82	256.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_286057_2	1469557.JSWF01000014_gene2609	8.8e-136	396.0	COG0438@1|root,COG0438@2|Bacteria,4NE0U@976|Bacteroidetes,1HWZH@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_286057_3	1380600.AUYN01000003_gene60	1.15e-101	311.0	COG3307@1|root,COG3307@2|Bacteria,4NGIS@976|Bacteroidetes,1HYGB@117743|Flavobacteriia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k59_1020538_1	1380600.AUYN01000006_gene689	2.84e-39	135.0	2E0H2@1|root,32W2Y@2|Bacteria,4NT2B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1020538_2	1380600.AUYN01000006_gene690	9.54e-73	224.0	COG0457@1|root,COG0457@2|Bacteria,4NM69@976|Bacteroidetes,1I0UE@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1754834_1	595494.Tola_3018	7.27e-65	206.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1Y3RH@135624|Aeromonadales	135624|Aeromonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1245704_1	1121935.AQXX01000139_gene3013	1.72e-43	160.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1XNC5@135619|Oceanospirillales	135619|Oceanospirillales	C	BFD-like [2Fe-2S] binding domain	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Pyr_redox_2
k59_1020556_1	1336235.JAEG01000001_gene2324	1.28e-08	57.8	COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,2U2K2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	methylamine dehydrogenase heavy	-	-	1.4.9.1	ko:K15229	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_H
k59_1020556_2	930169.B5T_00163	3.65e-33	123.0	2AFHJ@1|root,315I4@2|Bacteria,1QWX6@1224|Proteobacteria	1224|Proteobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
k59_1020556_3	930169.B5T_00162	4.9e-90	269.0	COG0526@1|root,COG0526@2|Bacteria,1R3WA@1224|Proteobacteria,1S5PZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	AhpC/TSA family	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_1020556_4	1396858.Q666_12210	5.39e-05	44.7	28V8Y@1|root,2ZHBX@2|Bacteria,1RD5G@1224|Proteobacteria,1S39W@1236|Gammaproteobacteria,46B4C@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Methylamine dehydrogenase, L chain	mauA	-	1.4.9.1	ko:K15228	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_L
k59_568329_1	572480.Arnit_0678	1.04e-43	152.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMVY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_568329_2	572480.Arnit_0677	4.07e-46	159.0	COG0642@1|root,COG0642@2|Bacteria,1Q01G@1224|Proteobacteria,42RFV@68525|delta/epsilon subdivisions,2YPCI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k59_794526_1	1123518.ARWI01000001_gene2017	4.26e-154	464.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,45ZMP@72273|Thiotrichales	72273|Thiotrichales	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_60223_1	1122225.AULQ01000001_gene1560	4.58e-52	171.0	28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,1I3WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60223_2	983544.Lacal_2849	4.11e-84	253.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1HX4U@117743|Flavobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_60223_3	1178825.ALIH01000012_gene1849	1.28e-152	429.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1HXFN@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_60223_4	745718.JADT01000012_gene867	4.13e-18	77.4	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_1698232_1	1380600.AUYN01000009_gene990	4.44e-131	392.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
k59_1415743_2	1380600.AUYN01000009_gene1556	2.27e-63	206.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_399174_1	929558.SMGD1_1145	9.76e-84	253.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,42VQT@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
k59_1585397_1	411154.GFO_3147	6.01e-40	135.0	COG2318@1|root,COG2318@2|Bacteria,4NUH8@976|Bacteroidetes,1I4KA@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
k59_1585397_2	655815.ZPR_0230	1.21e-78	239.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1HWPS@117743|Flavobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_511543_1	411154.GFO_1460	1.12e-178	520.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k59_568336_1	1129374.AJE_00210	1.11e-22	99.0	2B2R8@1|root,31VBA@2|Bacteria,1NBGB@1224|Proteobacteria,1S888@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
k59_568336_2	243924.LT42_17025	1.08e-05	48.1	2E9B9@1|root,333J4@2|Bacteria,1N9FM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1245727_1	929558.SMGD1_2867	8.89e-52	169.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2YNXY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_1245727_2	929558.SMGD1_2868	1.41e-43	153.0	COG0683@1|root,COG0683@2|Bacteria,1Q7JN@1224|Proteobacteria,42NDA@68525|delta/epsilon subdivisions,2YN6T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_455740_1	1347342.BN863_26220	2.1e-236	663.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1HWUY@117743|Flavobacteriia	976|Bacteroidetes	E	COG2303 Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
k59_1415767_1	1353276.JADR01000006_gene993	1.5e-138	415.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_1528587_1	1392490.JHZX01000001_gene1423	5.07e-109	323.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_1528587_2	1380600.AUYN01000007_gene3359	6e-34	119.0	2D460@1|root,32TGC@2|Bacteria,4NQMR@976|Bacteroidetes,1I4CI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_850310_1	1207076.ALAT01000099_gene2347	8.84e-27	110.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1YZSW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	JKL	Belongs to the DEAD box helicase family	srmB	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k59_1076191_1	1123326.JFBL01000001_gene1521	2.64e-05	50.8	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,42Q1Y@68525|delta/epsilon subdivisions,2YNR2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_455766_1	1172190.M947_04845	4.66e-49	172.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2YMB9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_455766_2	563040.Saut_0626	1.55e-32	117.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2YP0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_907469_1	1123228.AUIH01000007_gene2504	3.36e-107	320.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1XHZA@135619|Oceanospirillales	135619|Oceanospirillales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_850323_1	326298.Suden_1256	3.5e-53	175.0	COG0845@1|root,COG0845@2|Bacteria,1QZ27@1224|Proteobacteria,43CEE@68525|delta/epsilon subdivisions,2YTBZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_850323_2	326298.Suden_1255	3.44e-62	207.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2YMXA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_1303198_1	90814.KL370891_gene1230	2.88e-84	271.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales	72273|Thiotrichales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1303198_2	90814.KL370891_gene1231	5.95e-38	130.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,460NG@72273|Thiotrichales	72273|Thiotrichales	F	NUDIX domain	-	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_3737_2	323850.Shew_1613	3e-58	187.0	COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,2Q96C@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	PFAM Methyltransferase type 11	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
k59_3744_1	1250006.JHZZ01000001_gene1789	1.82e-67	233.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,1HWM9@117743|Flavobacteriia,3VX2E@52959|Polaribacter	976|Bacteroidetes	T	Histidine kinase	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
k59_3744_2	644966.Tmar_1372	4.91e-13	68.6	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,25B1X@186801|Clostridia,3WDTH@538999|Clostridiales incertae sedis	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_1189409_1	411154.GFO_0399	5.31e-127	372.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
k59_1189409_2	1121931.AUHG01000015_gene1147	2.89e-156	448.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_850338_1	563040.Saut_0580	5.55e-15	70.9	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2YN9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_963851_1	1380600.AUYN01000007_gene3128	2.08e-43	155.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_963851_2	1137281.D778_01822	1.91e-95	285.0	28NTK@1|root,2ZBS7@2|Bacteria,4NRK4@976|Bacteroidetes,1I19A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_963851_3	1197477.IA57_05420	1.32e-26	105.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_794624_1	1537917.JU82_06725	1.07e-78	248.0	COG0618@1|root,COG0618@2|Bacteria,1RADZ@1224|Proteobacteria,43DQA@68525|delta/epsilon subdivisions,2YT8A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_286185_1	1341181.FLJC2902T_08810	9e-18	80.5	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I4Y6@117743|Flavobacteriia,2NVZ8@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
k59_1471934_2	999141.GME_04962	6.86e-17	73.6	COG3609@1|root,COG3609@2|Bacteria,1N9NJ@1224|Proteobacteria,1S9Z4@1236|Gammaproteobacteria,1XMNS@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ParD_antitoxin
k59_173434_1	90814.KL370891_gene650	2.61e-170	501.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,4601R@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM aminopeptidase N, Escherichia coli type	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k59_1471942_1	1189620.AJXL01000051_gene1216	5.23e-228	652.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,1I0SZ@117743|Flavobacteriia,2NVHN@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k59_907526_1	411154.GFO_1955	3.46e-83	262.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia	976|Bacteroidetes	E	gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_1415843_1	1121931.AUHG01000010_gene319	1e-66	211.0	COG3023@1|root,COG3023@2|Bacteria,4NE38@976|Bacteroidetes,1HX02@117743|Flavobacteriia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	amiD	-	3.5.1.28	ko:K01447,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1
k59_1415843_2	1279009.ADICEAN_03777	1.29e-14	71.2	COG2120@1|root,COG2120@2|Bacteria,4PKC9@976|Bacteroidetes	976|Bacteroidetes	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	PIG-L
k59_1303255_1	411154.GFO_3265	1.46e-31	117.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_1303255_2	1121931.AUHG01000010_gene248	1.14e-40	141.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_850367_1	1469557.JSWF01000032_gene3217	3.63e-60	194.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_850367_2	1380600.AUYN01000009_gene1240	2.4e-235	649.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_850367_3	504487.JCM19302_568	8.33e-38	136.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_286212_1	1121285.AUFK01000002_gene29	3.09e-30	113.0	COG2852@1|root,COG2852@2|Bacteria,4NX7B@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1076269_1	421072.IO89_13415	4.91e-27	115.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1HZGJ@117743|Flavobacteriia,3HI1U@358033|Chryseobacterium	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1076269_2	714943.Mucpa_0722	3.9e-189	567.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1J0J3@117747|Sphingobacteriia	976|Bacteroidetes	H	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
k59_1471958_1	1123326.JFBL01000020_gene2656	2.78e-29	109.0	COG1247@1|root,COG1247@2|Bacteria,1R9WS@1224|Proteobacteria,42RZM@68525|delta/epsilon subdivisions,2YP9C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_1471958_2	760154.Sulba_0807	1.04e-28	110.0	COG3467@1|root,COG3467@2|Bacteria,1NEP5@1224|Proteobacteria,42TH0@68525|delta/epsilon subdivisions,2YQ47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Putative FMN-binding domain	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
k59_1077685_2	313603.FB2170_07924	5.64e-168	487.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_1643526_1	1380600.AUYN01000007_gene3147	7.11e-145	415.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,4NHRP@976|Bacteroidetes,1HXVY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_1643526_2	1380600.AUYN01000007_gene3146	4.27e-10	60.1	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1HZKN@117743|Flavobacteriia	976|Bacteroidetes	DZ	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LRR_4
k59_513086_1	411154.GFO_2695	2.34e-144	407.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1HZ9W@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
k59_513086_2	1121931.AUHG01000011_gene1827	6.74e-59	200.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_739463_1	1178825.ALIH01000001_gene2620	1.01e-119	350.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_739466_1	1249975.JQLP01000005_gene2362	4e-42	143.0	COG0778@1|root,COG0778@2|Bacteria,4NF4K@976|Bacteroidetes,1I1DI@117743|Flavobacteriia,2P6NV@244698|Gillisia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_739466_2	266748.HY04_01150	1.79e-47	162.0	COG1979@1|root,COG1979@2|Bacteria,4NF1D@976|Bacteroidetes,1HWZX@117743|Flavobacteriia,3ZQQV@59732|Chryseobacterium	976|Bacteroidetes	C	Aldehyde reductase	yqhD	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_61791_1	1172190.M947_10425	8.54e-98	292.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_1756417_1	1178825.ALIH01000001_gene2671	1.72e-36	134.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
k59_1756417_2	1380600.AUYN01000009_gene1797	3.95e-200	556.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,1HYU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
k59_1756417_3	1178825.ALIH01000001_gene2669	4.11e-60	191.0	COG1430@1|root,COG1430@2|Bacteria,4NQ5G@976|Bacteroidetes,1I2TF@117743|Flavobacteriia	976|Bacteroidetes	S	acr, cog1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
k59_1756417_4	1380600.AUYN01000003_gene154	2.25e-274	758.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1HYSK@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
k59_739474_1	944547.ABLL_1174	2.95e-58	189.0	2BV3K@1|root,32QGM@2|Bacteria,1Q4NH@1224|Proteobacteria,42ZI1@68525|delta/epsilon subdivisions,2YRN8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_739474_2	944547.ABLL_0234	1.21e-10	59.7	2BV3K@1|root,3187I@2|Bacteria,1PZXK@1224|Proteobacteria,430TM@68525|delta/epsilon subdivisions,2YS1S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_287650_1	392500.Swoo_4044	2.3e-63	205.0	COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,1RN1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,Haem_oxygenas_2,ketoacyl-synt
k59_343609_1	1122603.ATVI01000013_gene1386	3.72e-09	67.8	COG0657@1|root,COG3386@1|root,COG3391@1|root,COG0657@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
k59_1756424_1	323850.Shew_2748	5.97e-94	286.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,2Q8NM@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PAS PAC sensor signal transduction histidine kinase	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
k59_118095_1	867900.Celly_2429	3.98e-300	848.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,1F7X2@104264|Cellulophaga	976|Bacteroidetes	P	TonB dependent receptor	-	GO:0001871,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0004185,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0009987,GO:0010467,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030246,GO:0030247,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044421,GO:0051604,GO:0070008,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:2001070	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_118095_2	867900.Celly_2430	9.73e-197	558.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1HWRV@117743|Flavobacteriia,1F8FW@104264|Cellulophaga	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_639801_3	317025.Tcr_1110	8.39e-107	317.0	COG0484@1|root,COG0484@2|Bacteria,1NQPP@1224|Proteobacteria,1SMXQ@1236|Gammaproteobacteria,46250@72273|Thiotrichales	72273|Thiotrichales	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_639801_4	317025.Tcr_1109	7.79e-05	43.5	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,462BF@72273|Thiotrichales	72273|Thiotrichales	P	PhnA Zinc-Ribbon	-	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k59_1429695_2	1165841.SULAR_04217	2.92e-29	119.0	COG0477@1|root,COG2814@2|Bacteria,1R7DW@1224|Proteobacteria,43BJI@68525|delta/epsilon subdivisions,2YT98@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_356227_1	1249480.B649_01165	1.35e-95	297.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2YM9W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_130631_1	266762.HQ36_03285	7.27e-30	118.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,2FNHF@200643|Bacteroidia,22X4P@171551|Porphyromonadaceae	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_526323_1	1286632.P278_22360	2.58e-56	183.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_526323_2	1121912.AUHD01000001_gene2727	2.05e-33	126.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_300701_1	1123518.ARWI01000001_gene346	2.66e-108	326.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_300701_2	1123518.ARWI01000001_gene345	2.31e-155	441.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,460B4@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_809344_1	159087.Daro_1976	1.54e-53	190.0	COG3437@1|root,COG5001@1|root,COG3437@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVQ2@206389|Rhodocyclales	206389|Rhodocyclales	T	Response regulator receiver modulated diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_8,Response_reg
k59_356228_1	313594.PI23P_12267	1.31e-120	362.0	COG2207@1|root,COG2207@2|Bacteria,4NQ0S@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_356228_2	746697.Aeqsu_1820	2.38e-127	386.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes,1I1N3@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
k59_809353_1	563040.Saut_0410	3.45e-118	354.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2YN3S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Na H antiporter	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_639839_2	411154.GFO_2821	1.48e-46	150.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1I55H@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_639839_4	1121931.AUHG01000011_gene1700	2.97e-65	199.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_1656568_1	1396858.Q666_05230	3.14e-16	84.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,1RQ8F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
k59_188234_1	62928.azo2103	3.75e-106	326.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,2KUVE@206389|Rhodocyclales	206389|Rhodocyclales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_809371_1	1279009.ADICEAN_02206	4.04e-95	285.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KTK@768503|Cytophagia	976|Bacteroidetes	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_526367_1	1120977.JHUX01000003_gene1211	8.39e-40	150.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,3NIQ1@468|Moraxellaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF_2,GGDEF,MHYT,PAS_4,PAS_9
k59_356261_1	1121931.AUHG01000011_gene1811	8.02e-175	509.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_413619_1	1178825.ALIH01000006_gene1456	1.46e-138	397.0	COG4221@1|root,COG4221@2|Bacteria,4NGKR@976|Bacteroidetes,1HYM0@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	vdlC	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_300745_1	56107.Cylst_2087	1.99e-36	139.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIE5@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4
k59_17162_1	1380600.AUYN01000001_gene2340	1.78e-207	649.0	COG2304@1|root,COG3291@1|root,COG3391@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
k59_17162_2	1137281.D778_00164	5.29e-13	70.1	2EK5W@1|root,33DWA@2|Bacteria,4NY2G@976|Bacteroidetes,1I6AV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_865278_1	1353276.JADR01000010_gene1744	8.73e-88	271.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1HY1F@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
k59_865278_2	1380600.AUYN01000009_gene1654	6.08e-151	425.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCK@117743|Flavobacteriia	976|Bacteroidetes	H	gtp cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_17164_1	1387312.BAUS01000001_gene1345	2.17e-21	97.1	COG0760@1|root,COG0760@2|Bacteria,1R4EF@1224|Proteobacteria,2VK6Z@28216|Betaproteobacteria,2KN1F@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM peptidyl-prolyl cis-trans isomerase, EpsD family	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_2
k59_1090224_1	1168067.JAGP01000001_gene584	5.87e-104	333.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,461VE@72273|Thiotrichales	72273|Thiotrichales	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_921286_1	1173027.Mic7113_2237	3.91e-20	89.7	2D8WA@1|root,32TS3@2|Bacteria,1GEGY@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_921286_2	999411.HMPREF1092_00396	3.72e-25	111.0	COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,24N29@186801|Clostridia,36UWS@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_921286_3	1137281.D778_01132	2e-40	142.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1HXBD@117743|Flavobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_75302_1	411154.GFO_0956	2.27e-50	173.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_75302_2	411154.GFO_0958	1.92e-90	277.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1372851_1	9694.XP_007093073.1	1.12e-86	272.0	COG0649@1|root,KOG2870@2759|Eukaryota,38E8K@33154|Opisthokonta,3BADS@33208|Metazoa,3CS8G@33213|Bilateria,488M0@7711|Chordata,48YB9@7742|Vertebrata,3J7I4@40674|Mammalia,3ER62@33554|Carnivora	33208|Metazoa	C	NADH dehydrogenase ubiquinone	NDUFS2	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0019899,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031625,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070013,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k59_1260420_1	323850.Shew_2691	4.5e-75	228.0	COG3637@1|root,COG3637@2|Bacteria,1NBZC@1224|Proteobacteria,1SEIV@1236|Gammaproteobacteria,2QBWK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1487068_1	1178825.ALIH01000007_gene1706	4.63e-111	343.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1HXB5@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
k59_1318323_1	1123518.ARWI01000001_gene392	1.04e-63	197.0	2B5BG@1|root,31Y5N@2|Bacteria,1RJ1N@1224|Proteobacteria,1S56J@1236|Gammaproteobacteria,462WX@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188308_1	1348657.M622_00430	9.46e-06	47.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,2KUNG@206389|Rhodocyclales	206389|Rhodocyclales	E	HMGL-like	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_188308_2	85643.Tmz1t_0754	2.94e-24	92.8	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VXYJ@28216|Betaproteobacteria,2KXJB@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
k59_188308_3	305700.B447_12077	1.08e-22	88.6	COG3313@1|root,COG3313@2|Bacteria	2|Bacteria	S	Fe-S protein	RSC1457	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	Cys_rich_CWC,DUF1289,NUDIX
k59_188308_4	85643.Tmz1t_0756	9.9e-13	66.6	COG0491@1|root,COG0491@2|Bacteria,1NCIF@1224|Proteobacteria,2VJVR@28216|Betaproteobacteria,2KV3A@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1656644_1	76114.ebA7225	3.31e-105	322.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,2KUGP@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC transporter	abcZ	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_356331_1	637905.SVI_3244	3.34e-18	83.2	COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria,2QA0H@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k59_1769845_1	563040.Saut_0055	1.39e-132	395.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,42P6Y@68525|delta/epsilon subdivisions,2YMZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_244806_1	1380600.AUYN01000008_gene3439	7.03e-69	234.0	COG4932@1|root,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_526459_1	929558.SMGD1_0637	3.41e-48	157.0	COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria,42V9C@68525|delta/epsilon subdivisions,2YQ7A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_1600619_1	1121931.AUHG01000019_gene3055	4.54e-61	196.0	COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
k59_356338_1	317025.Tcr_0293	9.67e-193	540.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_1090291_1	572480.Arnit_2577	1.58e-87	272.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2YM8F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_583101_1	1121931.AUHG01000016_gene979	1.84e-136	392.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_583101_2	1121931.AUHG01000016_gene978	7.12e-11	62.0	COG3209@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,4NK97@976|Bacteroidetes,1HYP5@117743|Flavobacteriia	976|Bacteroidetes	E	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
k59_583103_1	1380600.AUYN01000009_gene1657	2.67e-147	426.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_75380_1	1168067.JAGP01000001_gene1730	5.63e-79	244.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,1RSB2@1236|Gammaproteobacteria,4612B@72273|Thiotrichales	72273|Thiotrichales	O	UreD urease accessory protein	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
k59_809492_1	675817.VDA_001990	2.35e-33	128.0	2E2J7@1|root,32XNR@2|Bacteria,1QK91@1224|Proteobacteria,1TICG@1236|Gammaproteobacteria,1XYVC@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF4238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4238
k59_526497_1	700598.Niako_5238	3.37e-11	71.2	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IVQU@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_526498_1	1122225.AULQ01000003_gene897	8.69e-92	277.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1I1CX@117743|Flavobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_300881_1	411154.GFO_1905	1.19e-17	79.7	COG0847@1|root,COG0847@2|Bacteria,4NMUI@976|Bacteroidetes,1I1K8@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_1374503_1	745718.JADT01000011_gene828	1.09e-23	90.1	2E359@1|root,32Y58@2|Bacteria,4NV78@976|Bacteroidetes,1I50N@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
k59_1374503_2	555500.I215_11389	1.52e-34	118.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_1374503_3	504487.JCM19302_706	7.75e-45	145.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_1374503_4	1178825.ALIH01000005_gene340	4.88e-89	274.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_976569_1	1353276.JADR01000006_gene1103	6.79e-26	103.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_976569_2	1197477.IA57_01145	5.54e-29	104.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
k59_976569_3	143224.JQMD01000002_gene3663	5.88e-07	50.4	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
k59_1036575_1	203275.BFO_1989	5.62e-17	79.7	COG0438@1|root,COG0438@2|Bacteria,4NEJ6@976|Bacteroidetes,2FMCY@200643|Bacteroidia,22Y9E@171551|Porphyromonadaceae	976|Bacteroidetes	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glycos_transf_1
k59_1714937_1	411154.GFO_1617	4.36e-161	454.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1HWU5@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_1714937_2	1121931.AUHG01000012_gene2562	1.4e-62	192.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1I2UU@117743|Flavobacteriia	976|Bacteroidetes	J	Translation initiation factor	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k59_302620_1	504487.JCM19302_1892	5.58e-115	334.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_302620_2	1380600.AUYN01000003_gene242	2.49e-55	179.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1HXZH@117743|Flavobacteriia	976|Bacteroidetes	S	porT protein	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1771532_1	1415778.JQMM01000001_gene990	4.71e-123	362.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1J55X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_1714952_1	929558.SMGD1_1743	8.45e-60	196.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2YMCS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_867074_1	1232410.KI421413_gene955	3.15e-84	259.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,43S04@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell cycle protein	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_976584_1	317025.Tcr_0454	2.99e-56	187.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,1SYRU@1236|Gammaproteobacteria,460YA@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_976584_2	90814.KL370891_gene1661	3.36e-189	542.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,1S6EB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_1148420_1	1122225.AULQ01000006_gene966	2.93e-171	483.0	COG4667@1|root,COG4667@2|Bacteria,4NF0K@976|Bacteroidetes,1HX96@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_1148420_2	1178825.ALIH01000006_gene1425	1.4e-06	48.9	COG4667@1|root,COG4667@2|Bacteria,4NF0K@976|Bacteroidetes,1HX96@117743|Flavobacteriia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_1148424_1	746697.Aeqsu_1147	2.89e-47	171.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_1543889_1	28072.Nos7524_4078	6.03e-19	91.7	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1G02W@1117|Cyanobacteria,1HQZB@1161|Nostocales	1117|Cyanobacteria	EQ	Hydantoinase/oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_1431463_1	1123514.KB905899_gene1482	1.52e-134	385.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,460HQ@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1431463_2	1123514.KB905899_gene1483	9.24e-94	297.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,45ZQ7@72273|Thiotrichales	72273|Thiotrichales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k59_1771574_1	1123514.KB905899_gene767	2.24e-26	104.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,462MK@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_1771574_2	1123517.JOMR01000001_gene851	1.25e-11	61.2	2C4DE@1|root,2ZD7H@2|Bacteria,1P4D3@1224|Proteobacteria,1SVWA@1236|Gammaproteobacteria,463FZ@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1771574_3	1123518.ARWI01000001_gene993	3.22e-112	333.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,460CK@72273|Thiotrichales	72273|Thiotrichales	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_77229_1	62928.azo3459	6.81e-81	244.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,2KVN5@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_753581_1	95619.PM1_0206985	5.65e-46	157.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_3433	Glyoxalase,Glyoxalase_5
k59_1200710_1	1121931.AUHG01000018_gene1329	2.33e-110	343.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1674392_1	1172190.M947_04825	3.02e-39	134.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_991189_1	1178825.ALIH01000001_gene2606	1.48e-113	327.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1HWK7@117743|Flavobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_991189_2	1380600.AUYN01000009_gene1277	1.08e-22	89.7	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_488361_1	411154.GFO_2730	5.87e-105	310.0	COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,1HY8V@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_1108080_1	1380600.AUYN01000010_gene842	1.12e-116	377.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1505587_1	1353276.JADR01000008_gene977	8.94e-68	207.0	COG3631@1|root,COG3631@2|Bacteria,4NPKS@976|Bacteroidetes,1I2EQ@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	DUF4440,SnoaL,SnoaL_2
k59_205963_1	267377.MMP0486	5.03e-41	138.0	COG1917@1|root,arCOG03444@2157|Archaea,2XWV3@28890|Euryarchaeota,23QV2@183939|Methanococci	183939|Methanococci	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_205963_2	339671.Asuc_1308	4.52e-19	89.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1S03K@1236|Gammaproteobacteria,1Y9B7@135625|Pasteurellales	135625|Pasteurellales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
k59_488376_1	563040.Saut_0687	8.15e-176	506.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_488376_2	929558.SMGD1_2162	5.08e-33	126.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2YMW4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1447021_1	502025.Hoch_1593	5.66e-54	191.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	502025.Hoch_1593|-	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_488391_1	319224.Sputcn32_3956	1.49e-116	345.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,2Q9JN@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658	ATP-synt_ab,ATP-synt_ab_N
k59_93042_1	1353528.DT23_03045	1.6e-111	330.0	COG3239@1|root,COG3239@2|Bacteria,1N42R@1224|Proteobacteria,2U06U@28211|Alphaproteobacteria,2XM82@285107|Thioclava	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
k59_373937_1	1172190.M947_04375	8.53e-113	332.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2YMK2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k59_543662_1	326298.Suden_1807	4.9e-49	167.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2YMI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_543662_2	1172190.M947_04250	1.36e-06	48.5	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2YMZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_716656_1	929558.SMGD1_2300	3.03e-37	136.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2YNYQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	ErfK YbiS YcfS YnhG family protein	pgp2	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_716656_2	929558.SMGD1_2299	1.53e-06	49.7	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2YMTA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	C-terminal domain of metallo-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k59_599524_1	572480.Arnit_1667	1.35e-134	400.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2YMVB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_1337039_1	563040.Saut_0115	3.37e-34	125.0	COG0697@1|root,COG0697@2|Bacteria,1R8RU@1224|Proteobacteria,42SDJ@68525|delta/epsilon subdivisions,2YPDW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1337039_2	929558.SMGD1_1402	3.86e-93	283.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions,2YN01@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fad-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1505643_1	1121931.AUHG01000011_gene2228	1.81e-162	487.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_148307_1	1178825.ALIH01000005_gene289	9.83e-138	401.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_488436_1	709032.Sulku_2313	5.71e-125	366.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2YMXT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_1787973_1	1046627.BZARG_1671	3.6e-69	223.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_1787973_2	1380600.AUYN01000007_gene3061	1.11e-25	99.8	2E7B3@1|root,331UH@2|Bacteria,4NUQ4@976|Bacteroidetes,1I5N0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_373984_1	929558.SMGD1_2279	8.87e-82	255.0	COG1729@1|root,COG1729@2|Bacteria,1NG81@1224|Proteobacteria,42R1Z@68525|delta/epsilon subdivisions,2YNY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	repeat protein	ybgF	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6
k59_716714_1	525898.Sdel_2130	2.1e-50	175.0	COG0642@1|root,COG2205@2|Bacteria,1Q4BK@1224|Proteobacteria,42YT8@68525|delta/epsilon subdivisions,2YR36@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c
k59_34355_1	323850.Shew_2948	1.21e-99	312.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,2Q91Q@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1165123_1	90814.KL370892_gene2333	6.51e-37	130.0	COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1RMZN@1236|Gammaproteobacteria,462HG@72273|Thiotrichales	72273|Thiotrichales	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
k59_1390655_1	1380600.AUYN01000006_gene485	1e-69	211.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,1I2YA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_93138_1	317025.Tcr_1148	5.03e-94	288.0	2DM3X@1|root,31MK7@2|Bacteria,1RFI0@1224|Proteobacteria,1S7WP@1236|Gammaproteobacteria,462FZ@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1788018_1	1121918.ARWE01000001_gene1757	2.09e-63	214.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,43U1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_1390657_1	572480.Arnit_1385	5.71e-53	184.0	COG2199@1|root,COG3706@2|Bacteria,1R48Q@1224|Proteobacteria,42SAH@68525|delta/epsilon subdivisions,2YPEM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_1390657_2	572480.Arnit_1384	7.03e-64	196.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2YPWP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_991334_1	491952.Mar181_0898	3.25e-58	191.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,1RR3X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_937742_1	945713.IALB_0586	1.67e-97	314.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
k59_431685_1	323097.Nham_1855	2.23e-08	51.2	COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,2UFMJ@28211|Alphaproteobacteria,3K4M7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_431685_2	323850.Shew_3763	4.08e-43	144.0	COG2197@1|root,COG2197@2|Bacteria,1N5JP@1224|Proteobacteria,1T0ZQ@1236|Gammaproteobacteria,2QESA@267890|Shewanellaceae	1236|Gammaproteobacteria	KT	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1560033_1	1122201.AUAZ01000015_gene774	1.15e-28	114.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,465P6@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0456 Acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k59_1560033_2	1123518.ARWI01000001_gene994	5.23e-27	108.0	COG1735@1|root,COG1735@2|Bacteria,1R149@1224|Proteobacteria,1T4US@1236|Gammaproteobacteria,463WX@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
k59_1674574_1	1189620.AJXL01000051_gene1215	1.92e-84	260.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k59_1278394_1	1347342.BN863_9500	1.13e-152	438.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1HWZC@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k59_545487_1	929558.SMGD1_1028	8.78e-43	146.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,42YWZ@68525|delta/epsilon subdivisions,2YRHN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
k59_545487_2	1172190.M947_08450	1.28e-15	75.9	COG2951@1|root,COG2951@2|Bacteria,1PPIK@1224|Proteobacteria,43ABD@68525|delta/epsilon subdivisions,2YQXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_1110644_1	411154.GFO_0943	2.37e-103	306.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,1HXB1@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1790432_1	318161.Sden_3325	7.61e-68	217.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,2QBDP@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_1110656_1	1121931.AUHG01000018_gene1325	2.98e-31	119.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
k59_1110656_2	362418.IW19_09565	1.13e-65	214.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1HY89@117743|Flavobacteriia,2NTBI@237|Flavobacterium	976|Bacteroidetes	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
k59_830710_1	1123228.AUIH01000033_gene2675	9.36e-94	300.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XI69@135619|Oceanospirillales	135619|Oceanospirillales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_939702_1	504487.JCM19302_3004	5.08e-68	211.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I1Y2@117743|Flavobacteriia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k59_1167510_1	1380600.AUYN01000009_gene1763	5.87e-107	315.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_1562403_1	929558.SMGD1_2824	9.94e-89	271.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions,2YQ7F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_1280757_1	717772.THIAE_03425	6.1e-116	347.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,460IV@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_36760_1	1178825.ALIH01000005_gene320	1.53e-173	501.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HY5T@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_1621399_1	1123518.ARWI01000001_gene1270	1.53e-142	404.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,460M6@72273|Thiotrichales	72273|Thiotrichales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,Redoxin
k59_1621399_2	90814.KL370891_gene33	3.58e-105	315.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,45ZZP@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_150785_1	392500.Swoo_4634	5.03e-100	306.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria,2Q9HB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k59_376276_1	641526.ADIWIN_3373	9.48e-07	56.2	COG3829@1|root,COG4191@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_4,PAS_9
k59_321387_1	1123518.ARWI01000001_gene2153	1.33e-40	140.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,46140@72273|Thiotrichales	72273|Thiotrichales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_321387_2	1123518.ARWI01000001_gene2152	5.38e-161	461.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,4606I@72273|Thiotrichales	72273|Thiotrichales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_993612_1	1380600.AUYN01000003_gene144	6.27e-55	177.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_993612_2	745718.JADT01000011_gene820	2.01e-120	354.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia	976|Bacteroidetes	C	dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_660412_1	867900.Celly_2432	0.0	902.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia,1F8X1@104264|Cellulophaga	976|Bacteroidetes	G	SMART Glycosyl hydrolase, family 13, subfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_1562432_1	305700.B447_17014	1.81e-27	101.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,2KWKM@206389|Rhodocyclales	206389|Rhodocyclales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_1562432_2	497321.C664_10468	2.56e-46	165.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k59_1733292_1	90814.KL370891_gene103	4.65e-53	174.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,45ZQB@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_1733292_2	1168067.JAGP01000001_gene143	2.01e-73	236.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales	72273|Thiotrichales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k59_1393106_1	1178825.ALIH01000001_gene2343	1.11e-59	187.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1I3Z8@117743|Flavobacteriia	976|Bacteroidetes	J	chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_1393106_2	391603.FBALC1_01432	1.62e-122	372.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,1IJ7E@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1339560_1	323850.Shew_3547	1.1e-35	126.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,2Q9HF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
k59_434164_1	504487.JCM19302_3108	1.69e-123	361.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_993646_1	323850.Shew_2893	1.58e-15	72.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,2QADE@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0234 family	yajQ	GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_1110734_1	929558.SMGD1_1129	1.42e-50	177.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2YNJP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	RNA binding S1 domain protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_1110734_2	714961.BFZC1_05788	0.00019	43.1	COG2199@1|root,COG3706@2|Bacteria,1TSGN@1239|Firmicutes,4HED7@91061|Bacilli,3IX2K@400634|Lysinibacillus	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_1053586_1	471874.PROSTU_01097	2.62e-21	86.3	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,1TEB6@1236|Gammaproteobacteria,3ZA81@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1733328_1	1380600.AUYN01000001_gene2271	3.4e-108	330.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_660458_1	1123514.KB905899_gene734	2.66e-91	279.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,460ED@72273|Thiotrichales	72273|Thiotrichales	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k59_660458_2	1123514.KB905899_gene733	7.01e-88	289.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,45ZUT@72273|Thiotrichales	72273|Thiotrichales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_1621461_1	929558.SMGD1_1278	4.8e-40	132.0	COG0828@1|root,COG0828@2|Bacteria,1Q61C@1224|Proteobacteria,42VSR@68525|delta/epsilon subdivisions,2YQAH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k59_208577_1	563040.Saut_1125	8.24e-67	206.0	COG0745@1|root,COG0745@2|Bacteria,1Q4AG@1224|Proteobacteria,42YR3@68525|delta/epsilon subdivisions,2YR20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_95671_2	411154.GFO_2927	6.57e-123	374.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
k59_150869_1	572480.Arnit_0423	5.37e-109	323.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_376347_1	1172190.M947_02290	2.29e-93	286.0	COG0457@1|root,COG0457@2|Bacteria,1Q55C@1224|Proteobacteria,42RCA@68525|delta/epsilon subdivisions,2YND3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	PPR
k59_885749_1	1185766.DL1_12935	1.22e-29	105.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria,2XNMR@285107|Thioclava	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_885749_2	1353528.DT23_13820	7.35e-58	180.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria,2XNEJ@285107|Thioclava	28211|Alphaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_1790558_1	1172190.M947_01460	4.8e-190	542.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,42MWP@68525|delta/epsilon subdivisions,2YNEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_321488_2	1172190.M947_10135	1.29e-185	521.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2YME1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	heptosyltransferase ii	waaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_36899_1	877420.ATVW01000063_gene349	9.5e-34	122.0	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,24DKZ@186801|Clostridia,27MJT@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_939824_1	305700.B447_18778	1.98e-70	219.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,2KWT1@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k59_619967_1	313596.RB2501_13084	3.68e-14	77.8	COG0642@1|root,COG0745@1|root,COG2207@1|root,COG3292@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,Y_Y_Y
k59_1633631_1	983544.Lacal_2608	3.58e-85	273.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_1013388_1	563040.Saut_0894	3.57e-83	253.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2YMPZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	hmm pf04305	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_1409511_1	1565129.JSFF01000008_gene2717	1.08e-94	276.0	COG0716@1|root,COG0716@2|Bacteria,1N30T@1224|Proteobacteria,1S403@1236|Gammaproteobacteria,2QC23@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM flavodoxin nitric oxide synthase	mioC	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051302,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06205	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k59_846584_1	1178825.ALIH01000004_gene2926	5.65e-14	70.1	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_846584_2	1380600.AUYN01000009_gene1591	5.78e-25	101.0	2E7DN@1|root,331WR@2|Bacteria,4NVC6@976|Bacteroidetes,1I5FN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_846584_3	1380600.AUYN01000009_gene1592	1.74e-96	284.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1I18Y@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1468335_1	1380600.AUYN01000003_gene223	8.15e-84	259.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
k59_1468335_2	1178825.ALIH01000008_gene762	8.71e-81	240.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1I21R@117743|Flavobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k59_1581024_1	1121931.AUHG01000019_gene3003	9.79e-34	126.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1581024_2	985255.APHJ01000039_gene114	3.27e-29	109.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia,2P7J2@244698|Gillisia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1409562_1	1121931.AUHG01000012_gene2863	2.47e-39	145.0	COG0668@1|root,COG0668@2|Bacteria,4NFX6@976|Bacteroidetes,1HWPR@117743|Flavobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_1409562_2	411154.GFO_1043	2.58e-163	462.0	COG3291@1|root,COG3291@2|Bacteria,4NMA6@976|Bacteroidetes,1IJ6Q@117743|Flavobacteriia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
k59_1232730_1	1117315.AHCA01000002_gene3188	3.09e-96	309.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q0X3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1581031_1	1123518.ARWI01000001_gene354	2.92e-93	291.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales	72273|Thiotrichales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_1581031_2	690597.JH730914_gene3880	5.72e-21	87.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbV	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
k59_1581031_3	1123518.ARWI01000001_gene351	3.67e-18	82.8	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,4606S@72273|Thiotrichales	72273|Thiotrichales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_620100_1	572480.Arnit_2617	3.02e-194	577.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_169673_5	1123517.JOMR01000001_gene1876	7.95e-05	42.4	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_678036_1	504487.JCM19302_1067	2.12e-121	349.0	COG0794@1|root,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_678036_2	1380600.AUYN01000003_gene48	7.3e-68	224.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k59_452064_1	1121931.AUHG01000011_gene2070	5.76e-159	451.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1HXIE@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_1355815_1	411154.GFO_2720	2.04e-132	385.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_1129955_1	1123517.JOMR01000001_gene1389	1.11e-111	347.0	COG4774@1|root,COG4774@2|Bacteria,1QV5G@1224|Proteobacteria,1T298@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1129955_2	1123517.JOMR01000001_gene1390	9.68e-15	73.6	COG0348@1|root,COG0348@2|Bacteria,1N605@1224|Proteobacteria,1RNU6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0348 Polyferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k59_1186432_1	1484460.JSWG01000009_gene527	2.49e-142	423.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k59_621557_1	317025.Tcr_1252	9.53e-127	369.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,4607F@72273|Thiotrichales	72273|Thiotrichales	E	PFAM Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1016974_2	1249480.B649_11360	3.13e-06	50.4	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k59_113186_1	323850.Shew_2351	3.15e-137	400.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,1RZIM@1236|Gammaproteobacteria,2Q8SU@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_1129957_1	945713.IALB_0012	1.02e-70	229.0	COG0486@1|root,COG0486@2|Bacteria	2|Bacteria	S	GTPase activity	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_508528_1	1121896.JMLU01000034_gene613	1.82e-58	182.0	COG3682@1|root,COG3682@2|Bacteria,4NT4V@976|Bacteroidetes,1I2YY@117743|Flavobacteriia,2NWAE@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
k59_508528_2	1380600.AUYN01000009_gene1671	1.11e-62	213.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HX6K@117743|Flavobacteriia	976|Bacteroidetes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
k59_226186_1	1121904.ARBP01000030_gene1950	3.07e-70	238.0	COG0860@1|root,COG1649@1|root,COG0860@2|Bacteria,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,47KD5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Uncharacterised BCR, COG1649	yngK	-	-	-	-	-	-	-	-	-	-	-	GHL10
k59_847420_1	313603.FB2170_14833	1.14e-246	709.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PG6S@252356|Maribacter	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
k59_847420_2	313603.FB2170_14828	1.48e-93	283.0	28PU4@1|root,2ZCF6@2|Bacteria,4NTXA@976|Bacteroidetes,1I497@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_621586_1	411154.GFO_3353	5.32e-107	317.0	COG0787@1|root,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1HWKS@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
k59_1694804_1	90814.KL370891_gene1825	4.03e-192	538.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,45ZRJ@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_565106_1	880073.Calab_0923	5.15e-37	141.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	ebh	-	-	-	-	-	-	-	-	-	-	-	DUF1611,Inhibitor_I9,Peptidase_S8,SLH
k59_1186437_1	399741.Spro_4921	2.39e-74	238.0	COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,1RRK4@1236|Gammaproteobacteria,404AH@613|Serratia	1236|Gammaproteobacteria	S	Phage portal protein, lambda family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
k59_1186437_2	1476902.A0A067ZJ01_9CAUD	2.71e-30	108.0	4QB54@10239|Viruses,4QUK9@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1186437_3	1476902.A0A067ZJA1_9CAUD	7.42e-316	875.0	4QAXX@10239|Viruses,4QV9W@35237|dsDNA viruses  no RNA stage,4QPTB@28883|Caudovirales,4QHV2@10662|Myoviridae	10662|Myoviridae	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1186437_5	742823.HMPREF9465_00225	1.11e-189	540.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2VKJR@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM DNA methylase N-4 N-6	yhdJ	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k59_1186437_6	1476902.A0A067ZI74_9CAUD	1.67e-79	243.0	4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QII1@10662|Myoviridae	10662|Myoviridae	S	N-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_734538_1	62928.azo2418	3.19e-99	296.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VK9M@28216|Betaproteobacteria,2KVAU@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapB	-	1.2.1.72	ko:K03472	ko00750,ko01100,map00750,map01100	M00124	R01825	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Gp_dh_C,Gp_dh_N
k59_1468810_1	425104.Ssed_0010	1.11e-13	70.1	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,2QAMG@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0271 (lamB) family	ybgL	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k59_1468810_2	1565129.JSFF01000008_gene2704	1.63e-69	229.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,2Q924@267890|Shewanellaceae	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_56772_1	411154.GFO_2793	1.28e-140	404.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1HYV6@117743|Flavobacteriia	976|Bacteroidetes	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_565119_1	370438.PTH_1115	7.12e-10	61.6	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,2.6.1.102	ko:K12452,ko:K13010	ko00520,map00520	-	R03391,R03392,R10460	RC00006,RC00230,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_565119_2	945713.IALB_2966	2.33e-16	79.7	28JDJ@1|root,2Z97V@2|Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
k59_395687_1	458817.Shal_3399	3.6e-112	343.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,2Q9SB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TIGRFAM TonB-dependent hemoglobin transferrin lactoferrin family receptor	hmuR	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042221,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071944	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_621629_1	1123261.AXDW01000003_gene1860	1.89e-64	202.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1X6GJ@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_960500_1	1202532.FF52_14629	8.64e-236	662.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1HZGJ@117743|Flavobacteriia,2NSWT@237|Flavobacterium	976|Bacteroidetes	S	Carbohydrate-binding protein SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_960500_2	1202532.FF52_14634	1.04e-76	243.0	COG3291@1|root,COG3291@2|Bacteria,4NRIG@976|Bacteroidetes,1I3TW@117743|Flavobacteriia,2NTVQ@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
k59_960500_3	991.IW20_15125	2.03e-250	698.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
k59_1525388_1	929558.SMGD1_0049	8.27e-29	110.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2YMG4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_1525388_2	929558.SMGD1_2253	1.54e-39	132.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,42VQC@68525|delta/epsilon subdivisions,2YQ7P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k59_1525388_3	1537917.JU82_09430	5.68e-70	221.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2YMQU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_791089_1	1380600.AUYN01000009_gene1911	2.04e-119	379.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k59_1130043_2	1056820.KB900696_gene3979	1.52e-28	115.0	COG1092@1|root,COG3199@1|root,COG1092@2|Bacteria,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,2PMXE@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
k59_452156_1	1392490.JHZX01000001_gene329	6.39e-20	87.8	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_452156_2	1484460.JSWG01000008_gene1921	1.47e-110	330.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
k59_282687_1	411154.GFO_2542	1.06e-202	574.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
k59_1581890_1	504487.JCM19302_299	6.09e-213	595.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,1HY91@117743|Flavobacteriia	976|Bacteroidetes	S	protein related to deoxyribodipyrimidine photolyase	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k59_1581890_2	1484460.JSWG01000015_gene1055	5.93e-264	733.0	COG0415@1|root,COG0415@2|Bacteria,4NH55@976|Bacteroidetes,1HWKI@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phrB2	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1581890_3	983544.Lacal_2161	3.92e-63	196.0	2AHD2@1|root,317Q0@2|Bacteria,4NQE4@976|Bacteroidetes,1I319@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1581890_4	1469557.JSWF01000019_gene451	2.23e-38	130.0	COG2963@1|root,COG2963@2|Bacteria,4NSB9@976|Bacteroidetes,1I3XZ@117743|Flavobacteriia	976|Bacteroidetes	L	Protein of unknown function (DUF2805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2805
k59_1581890_5	616991.JPOO01000001_gene3945	2.64e-62	196.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCK@117743|Flavobacteriia,23G1J@178469|Arenibacter	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1638416_1	985255.APHJ01000030_gene2484	1.41e-36	137.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.80,3.4.24.40	ko:K01406,ko:K03332	ko00051,ko01503,map00051,map01503	-	R00879	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_6,F5_F8_type_C,FIVAR,He_PIG,LVIVD,Laminin_G_3,SLH,TSP_3
k59_1638416_2	1121931.AUHG01000011_gene2286	3.15e-12	66.2	COG3209@1|root,COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Reprolysin_4,TSP_3
k59_1412481_1	1284775.HMPREF1640_07840	8.65e-37	133.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia	976|Bacteroidetes	JM	Nucleotidyl transferase	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
k59_1412481_2	1235803.C825_03456	3.81e-25	104.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,2FMEM@200643|Bacteroidia,22VZD@171551|Porphyromonadaceae	976|Bacteroidetes	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
k59_226280_1	1121912.AUHD01000008_gene204	3.24e-39	137.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1HX48@117743|Flavobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_226280_2	1198676.SMUGS5_07025	0.000408	44.7	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,4HCRM@91061|Bacilli	91061|Bacilli	P	Potassium transporter peripheral membrane component	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_847475_1	1280663.ATVR01000003_gene139	7.07e-05	47.8	28IN0@1|root,2Z8NG@2|Bacteria,1VUP7@1239|Firmicutes,2583Y@186801|Clostridia,4BZY6@830|Butyrivibrio	186801|Clostridia	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
k59_847475_2	865937.Gilli_0723	1.8e-20	93.6	2FCB9@1|root,344EV@2|Bacteria,4P53U@976|Bacteroidetes,1IA9F@117743|Flavobacteriia,2P789@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1242954_1	572480.Arnit_2654	8.19e-105	317.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k59_621669_1	572480.Arnit_0808	8.1e-48	167.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MA6@68525|delta/epsilon subdivisions,2YMMG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_621669_2	927704.SELR_25320	1.73e-19	85.9	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H1XC@909932|Negativicutes	909932|Negativicutes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
k59_1751388_1	65393.PCC7424_4417	1.16e-21	93.2	COG0804@1|root,COG0804@2|Bacteria,1G12D@1117|Cyanobacteria,3KHFK@43988|Cyanothece	1117|Cyanobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
k59_1751388_2	1168067.JAGP01000001_gene1728	1.45e-52	167.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,460WS@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
k59_1751388_3	1168067.JAGP01000001_gene1729	1.77e-60	186.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,1S65Y@1236|Gammaproteobacteria,460SU@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
k59_282705_1	929558.SMGD1_1137	2.15e-182	523.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2YN8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k59_339152_1	1121931.AUHG01000010_gene761	5.34e-121	356.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_1525426_1	1042375.AFPL01000013_gene2445	7.6e-38	138.0	COG3181@1|root,COG3181@2|Bacteria,1N0TT@1224|Proteobacteria,1S8WC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k59_1525426_2	1112217.PPL19_00990	1.27e-07	55.5	COG0583@1|root,COG0583@2|Bacteria,1MUWX@1224|Proteobacteria,1RYWC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	ybhD	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_678179_2	1349785.BAUG01000008_gene644	7.59e-53	183.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_791132_2	616991.JPOO01000003_gene1978	3.45e-72	223.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1HZJ2@117743|Flavobacteriia,23GG6@178469|Arenibacter	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1638442_1	867900.Celly_0857	1.24e-118	364.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
k59_1412499_1	123214.PERMA_0986	3.22e-32	130.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G5H0@200783|Aquificae	200783|Aquificae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD
k59_1186537_1	1380600.AUYN01000009_gene2017	1.03e-87	264.0	COG0500@1|root,COG0500@2|Bacteria,4NFKM@976|Bacteroidetes,1IJCK@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
k59_858754_1	342610.Patl_2284	1.04e-39	145.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,2Q3UA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_294345_1	326298.Suden_1017	8.03e-101	297.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2YMJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k59_1311754_1	90814.KL370892_gene2059	4.45e-144	421.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,460GF@72273|Thiotrichales	72273|Thiotrichales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_1311754_2	553385.JEMF01000070_gene1181	7.45e-23	97.4	COG0789@1|root,COG0789@2|Bacteria,1R9SN@1224|Proteobacteria,1S78T@1236|Gammaproteobacteria,1XS60@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_691976_5	1175654.A0A0S0NAE3_9CAUD	1.57e-184	531.0	4QB5I@10239|Viruses,4QWYV@35237|dsDNA viruses  no RNA stage,4QTTK@28883|Caudovirales,4QM8X@10699|Siphoviridae	10699|Siphoviridae	S	ATP-dependent DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_295785_1	338963.Pcar_1328	2.04e-120	372.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,43S1C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine (FGAM) synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_351523_1	1123228.AUIH01000003_gene798	3.18e-91	295.0	COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,1XNK7@135619|Oceanospirillales	135619|Oceanospirillales	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
k59_125920_1	1380600.AUYN01000006_gene655	1.54e-182	532.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k59_125920_2	1380600.AUYN01000006_gene657	8.56e-42	150.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_1651671_2	1123514.KB905899_gene1521	1.21e-76	237.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,1S3KS@1236|Gammaproteobacteria,461IP@72273|Thiotrichales	72273|Thiotrichales	S	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
k59_1651671_3	1123514.KB905899_gene1522	2.36e-56	179.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria	1224|Proteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1651671_4	1123514.KB905899_gene1523	9.66e-10	58.9	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,45ZYN@72273|Thiotrichales	72273|Thiotrichales	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k59_1255509_1	411154.GFO_1955	1.11e-87	274.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia	976|Bacteroidetes	E	gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_1425083_1	926562.Oweho_2655	1.01e-30	110.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia,2PAY2@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM Iron-sulfur cluster assembly accessory protein	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k59_1425083_2	655815.ZPR_0215	1e-43	155.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia	976|Bacteroidetes	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k59_1764811_1	944546.ABED_2143	9.95e-47	154.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,42TIU@68525|delta/epsilon subdivisions,2YPSB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_1764811_2	1537917.JU82_02060	1.31e-07	53.1	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2YNNE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_295797_1	1168067.JAGP01000001_gene1934	2.59e-98	300.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4601I@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase accessory protein FixG	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_860309_1	323850.Shew_2527	1.17e-94	295.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria,2QA00@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
k59_125944_1	929558.SMGD1_2795	8.09e-106	322.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42YPX@68525|delta/epsilon subdivisions,2YRHK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1255526_2	745718.JADT01000001_gene1807	1.38e-209	598.0	COG1629@1|root,COG4771@2|Bacteria,4NFKZ@976|Bacteroidetes,1HY23@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_408815_1	929558.SMGD1_0782	8.75e-49	163.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2YNY5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_125956_1	1123514.KB905899_gene1577	1.47e-38	137.0	COG1344@1|root,COG1344@2|Bacteria,1MWE0@1224|Proteobacteria,1RYAM@1236|Gammaproteobacteria,462FI@72273|Thiotrichales	72273|Thiotrichales	N	Bacterial flagellin C-terminal helical region	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_351566_2	326298.Suden_1163	4.56e-54	187.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_521452_1	326298.Suden_1753	3.96e-138	400.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2YMDF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_239812_1	1123514.KB905899_gene1394	5.37e-89	289.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,45ZVJ@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_578469_1	572480.Arnit_3120	1.93e-58	194.0	COG0457@1|root,COG0457@2|Bacteria,1MWHE@1224|Proteobacteria,42S1C@68525|delta/epsilon subdivisions,2YNIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_16
k59_578469_2	572480.Arnit_1949	5.99e-88	275.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,42SEW@68525|delta/epsilon subdivisions,2YPKM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
k59_1595589_1	929558.SMGD1_2472	5.23e-100	295.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2YMFJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_1595589_2	929558.SMGD1_2473	1.79e-120	353.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2YM9A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_916782_1	314287.GB2207_01292	7.46e-15	74.7	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1J5MP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
k59_916782_2	6239.C05A9.1a	1.75e-20	91.7	COG1132@1|root,KOG0055@2759|Eukaryota,38E88@33154|Opisthokonta,3B958@33208|Metazoa,3CVKH@33213|Bilateria	33208|Metazoa	Q	ATPase activity, coupled to transmembrane movement of substances	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0010035,GO:0010038,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042742,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0046686,GO:0046688,GO:0050829,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071944,GO:0093002,GO:0097501,GO:0098542,GO:1990169,GO:1990170	-	ko:K02021,ko:K05660	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.201,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_1255568_1	983544.Lacal_0546	7.03e-176	499.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1255568_2	1380600.AUYN01000006_gene282	3.53e-102	301.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1I27S@117743|Flavobacteriia	976|Bacteroidetes	M	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
k59_1313312_1	572480.Arnit_1247	8.55e-79	248.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2YM7Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_916790_1	929558.SMGD1_2224	2.25e-11	64.3	COG1538@1|root,COG1538@2|Bacteria,1PBTH@1224|Proteobacteria,42R59@68525|delta/epsilon subdivisions,2YP2M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_916790_2	929558.SMGD1_2223	1.29e-30	115.0	COG1309@1|root,COG1309@2|Bacteria,1PFK7@1224|Proteobacteria,42UZC@68525|delta/epsilon subdivisions,2YQ5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
k59_1595609_1	1123256.KB907928_gene1991	3.56e-19	87.4	COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,1S6W5@1236|Gammaproteobacteria,1X7SX@135614|Xanthomonadales	135614|Xanthomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1595609_2	1123401.JHYQ01000047_gene168	3.56e-15	72.4	COG5331@1|root,COG5331@2|Bacteria,1N7DJ@1224|Proteobacteria,1SCVF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
k59_295886_1	572480.Arnit_2619	8.9e-102	296.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2YT60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_295886_2	572480.Arnit_2620	1.26e-34	124.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2YMN7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_1537793_1	317025.Tcr_0094	4.03e-87	269.0	COG2223@1|root,COG2223@2|Bacteria,1QVX0@1224|Proteobacteria,1T2MB@1236|Gammaproteobacteria,461YK@72273|Thiotrichales	72273|Thiotrichales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1764919_1	1216007.AOPM01000079_gene1139	2.05e-05	47.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,2Q11N@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	EH	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	pabC	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366	Aminotran_4
k59_1764919_2	1123518.ARWI01000001_gene551	8.88e-155	447.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,45ZY0@72273|Thiotrichales	72273|Thiotrichales	EH	Anthranilate synthase component I	-	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_408901_1	572480.Arnit_0905	2.09e-151	430.0	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions,2YM84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_578543_1	572480.Arnit_3120	7.61e-58	193.0	COG0457@1|root,COG0457@2|Bacteria,1MWHE@1224|Proteobacteria,42S1C@68525|delta/epsilon subdivisions,2YNIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_16
k59_916830_1	1123518.ARWI01000001_gene1867	4.87e-61	209.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4624A@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_351649_1	985255.APHJ01000019_gene708	1.96e-38	145.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia,2P6I0@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function (DUF4131)	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
k59_351649_2	411154.GFO_2969	2.03e-23	93.2	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
k59_239890_1	1123518.ARWI01000001_gene1228	1.71e-103	343.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
k59_578555_1	335659.S23_58950	1.28e-88	264.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2TRJR@28211|Alphaproteobacteria,3JTSH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_860456_1	655815.ZPR_0458	5.55e-160	459.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_183502_1	411154.GFO_2973	1.16e-111	332.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
k59_1764960_1	620914.JH621287_gene1402	6.97e-78	244.0	COG1819@1|root,COG1819@2|Bacteria,4NFYF@976|Bacteroidetes,1HZ4S@117743|Flavobacteriia	976|Bacteroidetes	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
k59_1708287_1	1208321.D104_11795	3.91e-15	74.3	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1XJ51@135619|Oceanospirillales	135619|Oceanospirillales	G	Glycoside hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_1708287_2	491952.Mar181_0143	5.19e-25	101.0	COG1309@1|root,COG1309@2|Bacteria,1NMHE@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1595686_1	1123248.KB893328_gene923	1.7e-162	466.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_70398_1	264198.Reut_B5268	1.45e-30	126.0	COG1075@1|root,COG1075@2|Bacteria,1RAUT@1224|Proteobacteria,2VJQZ@28216|Betaproteobacteria,1K7EM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	LCAT,PGAP1
k59_1195825_1	985255.APHJ01000025_gene1054	9.84e-54	177.0	COG0561@1|root,COG0561@2|Bacteria,4NICE@976|Bacteroidetes,1I0BU@117743|Flavobacteriia,2P61G@244698|Gillisia	976|Bacteroidetes	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_1195825_2	1380600.AUYN01000001_gene2700	1.12e-120	366.0	COG0495@1|root,COG0495@2|Bacteria,4PKSC@976|Bacteroidetes,1IJEG@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
k59_408953_1	926556.Echvi_2700	1.51e-68	209.0	COG1607@1|root,COG1607@2|Bacteria,4NNG1@976|Bacteroidetes,47QJI@768503|Cytophagia	976|Bacteroidetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_1425235_1	497321.C664_15138	1.84e-62	201.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,2WEG0@28216|Betaproteobacteria,2KYGY@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_465834_1	1484460.JSWG01000008_gene1959	1.61e-101	322.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 3	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
k59_578597_1	326298.Suden_1864	2.13e-233	647.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2YN6C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidase U32 family	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_1425243_1	1380600.AUYN01000007_gene3399	3.57e-26	102.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1425243_2	1137281.D778_02108	2.49e-88	261.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,1I1CY@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1425243_3	1121912.AUHD01000002_gene3274	6.31e-62	195.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1HYCZ@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_860509_1	944547.ABLL_1138	1.26e-77	237.0	COG0745@1|root,COG0745@2|Bacteria,1Q456@1224|Proteobacteria,42RZX@68525|delta/epsilon subdivisions,2YP60@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_70435_1	1178825.ALIH01000004_gene2885	4.01e-86	259.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1HXIX@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_70435_2	1111730.ATTM01000006_gene2682	7.33e-27	101.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1I2YF@117743|Flavobacteriia,2NWF0@237|Flavobacterium	976|Bacteroidetes	O	Peroxiredoxin	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
k59_1368112_1	563040.Saut_1453	1.49e-249	704.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2YMFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_1368112_2	1355374.JARU01000020_gene857	2.39e-35	132.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42NU0@68525|delta/epsilon subdivisions,2YN8B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_916882_1	572480.Arnit_2654	1.01e-181	517.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k59_916882_2	572480.Arnit_2655	2.51e-98	286.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_1537872_1	748247.AZKH_4002	3.74e-106	325.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KUP0@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_408995_1	1123518.ARWI01000001_gene2406	7.69e-166	475.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,460B0@72273|Thiotrichales	72273|Thiotrichales	T	PFAM PhoH-like protein	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_804617_1	326298.Suden_0500	4.6e-195	573.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MWW@68525|delta/epsilon subdivisions,2YMMH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1425273_1	317025.Tcr_1142	5.72e-271	761.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,45ZS8@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the aconitase IPM isomerase family	-	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k59_521636_1	1046629.Ssal_00680	2.87e-09	58.5	COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1VATJ@1239|Firmicutes,4HG1M@91061|Bacilli	91061|Bacilli	M	family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8,Glycos_transf_2
k59_12880_1	929558.SMGD1_0365	4.21e-61	198.0	COG3087@1|root,COG3087@2|Bacteria,1RKEG@1224|Proteobacteria	1224|Proteobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1085761_1	425104.Ssed_0248	1.06e-61	194.0	2E1Q2@1|root,32X0F@2|Bacteria,1N5E8@1224|Proteobacteria,1S9XB@1236|Gammaproteobacteria,2QBKQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function VcgC/VcgE (DUF2780)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2780
k59_1085761_2	637905.SVI_0224	1.73e-05	45.4	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,2QBRI@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_1085764_1	90814.KL370891_gene897	2.99e-163	468.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
k59_1273648_2	1178825.ALIH01000005_gene245	1.48e-264	730.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
k59_1273648_3	504487.JCM19302_305	4.04e-60	190.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1HZGZ@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_933947_1	1133849.O3I_010925	4.21e-24	107.0	COG0827@1|root,COG0827@2|Bacteria,2I3XK@201174|Actinobacteria,4FWT4@85025|Nocardiaceae	201174|Actinobacteria	L	TaqI-like C-terminal specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Methyltransf_31,N6_Mtase,TaqI_C
k59_711885_1	929558.SMGD1_2539	3.47e-83	259.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2YMFV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_1208181_1	504487.JCM19302_501	5.76e-167	473.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1HZAN@117743|Flavobacteriia	976|Bacteroidetes	E	argininosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_1500830_1	1121912.AUHD01000004_gene2131	7.92e-164	472.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_1614697_1	1137281.D778_00821	2.41e-265	733.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_314196_1	1177154.Y5S_03025	9.58e-86	271.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1XH4D@135619|Oceanospirillales	135619|Oceanospirillales	E	GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_595734_1	1197477.IA57_07695	1.15e-143	426.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1HWNZ@117743|Flavobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_1273676_1	1249975.JQLP01000008_gene366	5.41e-204	583.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia,2P5UH@244698|Gillisia	976|Bacteroidetes	P	Peroxidase	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_823643_1	857087.Metme_4026	7.91e-69	238.0	COG0642@1|root,COG0715@1|root,COG0784@1|root,COG0834@1|root,COG0715@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T5BY@1236|Gammaproteobacteria,1XF03@135618|Methylococcales	135618|Methylococcales	T	Bacterial periplasmic substrate-binding proteins	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,NMT1,PAS_3,Response_reg,SBP_bac_3
k59_314206_1	411154.GFO_0556	1.09e-105	313.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1HYF4@117743|Flavobacteriia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_1332279_2	382245.ASA_0726	8.88e-43	144.0	COG1522@1|root,COG1522@2|Bacteria,1RISV@1224|Proteobacteria,1S78M@1236|Gammaproteobacteria,1Y62Z@135624|Aeromonadales	135624|Aeromonadales	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
k59_1385917_2	709032.Sulku_1513	1.95e-09	56.6	COG2077@1|root,COG2077@2|Bacteria,1Q5Y2@1224|Proteobacteria,4321Y@68525|delta/epsilon subdivisions,2YS92@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_1726270_2	1172190.M947_03240	1.95e-56	191.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2YNXX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_258619_1	406340.A4PE69_9CAUD	3.16e-75	249.0	4QAY9@10239|Viruses,4QUV8@35237|dsDNA viruses  no RNA stage,4QPFD@28883|Caudovirales,4QIII@10662|Myoviridae	10662|Myoviridae	S	hydrolase activity, acting on acid anhydrides	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1208216_1	653733.Selin_0943	4.68e-22	98.6	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k59_539769_1	393595.ABO_0168	2e-57	199.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1XIN2@135619|Oceanospirillales	135619|Oceanospirillales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_88441_1	572480.Arnit_0310	3.69e-07	50.4	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2YMHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_88441_3	572480.Arnit_0312	3.05e-40	136.0	COG3209@1|root,COG3209@2|Bacteria,1QZNJ@1224|Proteobacteria,43CMG@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_30017_1	1380600.AUYN01000006_gene605	8.05e-131	380.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1HY7T@117743|Flavobacteriia	976|Bacteroidetes	C	aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_201539_1	945713.IALB_2869	1.68e-41	149.0	COG2262@1|root,COG2262@2|Bacteria	2|Bacteria	O	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_1442677_1	314256.OG2516_17845	3.39e-14	71.6	2DBK2@1|root,2Z9Q1@2|Bacteria,1NTTR@1224|Proteobacteria,2UPZJ@28211|Alphaproteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1442677_2	90813.JQMT01000001_gene1207	7.61e-46	147.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,460WE@72273|Thiotrichales	72273|Thiotrichales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_1442677_3	1123518.ARWI01000001_gene210	1.31e-66	203.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,460SS@72273|Thiotrichales	72273|Thiotrichales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_1442677_4	1123518.ARWI01000001_gene211	6.43e-65	204.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,4603F@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_258650_1	159450.NH14_09590	6.49e-27	107.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VJ0X@28216|Betaproteobacteria,1K1TD@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k59_258650_2	1218084.BBJK01000021_gene2265	5.27e-28	107.0	COG0404@1|root,COG0404@2|Bacteria,1N2I3@1224|Proteobacteria,2VVMU@28216|Betaproteobacteria,1KC75@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Sarcosine oxidase, gamma subunit family	-	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
k59_653277_1	999549.KI421514_gene26	2.31e-23	92.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,281KA@191028|Leisingera	28211|Alphaproteobacteria	E	Nitrogen regulatory protein P-II	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_653277_2	1192124.LIG30_3847	4.34e-41	147.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1K0BN@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_143832_1	1137281.D778_00361	1.02e-152	437.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWRC@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_1047801_1	709032.Sulku_1860	8.44e-72	240.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2YMD8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_595812_1	944546.ABED_1648	1.05e-45	156.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2YMGM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_595812_2	1355368.JART01000023_gene1458	6.08e-69	217.0	COG1216@1|root,COG1216@2|Bacteria,1QV95@1224|Proteobacteria,42QIJ@68525|delta/epsilon subdivisions,2YQ78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_595813_1	1178825.ALIH01000003_gene2213	9.56e-88	266.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1HX72@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1385992_1	1123514.KB905899_gene2032	4.23e-60	204.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,4609C@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k59_765145_1	616991.JPOO01000001_gene4247	2.17e-78	253.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_765145_2	1380600.AUYN01000001_gene2416	1.15e-96	282.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_765145_3	1178825.ALIH01000002_gene981	5.69e-132	382.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,1HY3H@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_1442711_1	232346.JHQL01000005_gene3184	8.71e-34	132.0	COG2176@1|root,COG2176@2|Bacteria,1MUZD@1224|Proteobacteria,1RPGP@1236|Gammaproteobacteria,1XJ58@135619|Oceanospirillales	135619|Oceanospirillales	L	VRR_NUC	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
k59_1103605_1	1537917.JU82_08555	2.6e-71	220.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42RV5@68525|delta/epsilon subdivisions,2YP89@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1103605_2	1165841.SULAR_00525	1.11e-73	224.0	COG1846@1|root,COG1846@2|Bacteria,1ND45@1224|Proteobacteria,42UP2@68525|delta/epsilon subdivisions,2YQ0G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k59_1103605_3	709032.Sulku_1038	1.83e-81	251.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1273804_1	85643.Tmz1t_1998	3.86e-26	107.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,2VHWD@28216|Betaproteobacteria,2KVTR@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_1208266_1	1380600.AUYN01000009_gene1458	9.63e-217	605.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_143879_1	1121373.KB903632_gene485	5.67e-39	134.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
k59_143879_2	1237149.C900_00266	5.74e-67	221.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1442732_1	572480.Arnit_2617	7.55e-155	471.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2YMMS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_30074_1	1392489.JPOL01000002_gene1283	1.35e-207	592.0	COG4733@1|root,COG4733@2|Bacteria,4PNDB@976|Bacteroidetes,1HZQB@117743|Flavobacteriia	976|Bacteroidetes	N	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,DUF4990
k59_765179_1	402626.Rpic_3108	2.73e-30	124.0	COG1080@1|root,COG4668@1|root,COG1080@2|Bacteria,COG4668@2|Bacteria,1MUT8@1224|Proteobacteria,2VJ9V@28216|Betaproteobacteria,1K02U@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	fruB	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
k59_1386039_1	387093.SUN_1613	2.32e-67	213.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2YMPG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_1386039_2	326298.Suden_0635	1.89e-65	202.0	COG2862@1|root,COG2862@2|Bacteria,1NFSW@1224|Proteobacteria,43ACB@68525|delta/epsilon subdivisions,2YT0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k59_88520_1	1123518.ARWI01000001_gene500	4.53e-81	266.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,461P3@72273|Thiotrichales	72273|Thiotrichales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
k59_1442747_2	203275.BFO_0277	0.000108	44.3	COG3152@1|root,COG3152@2|Bacteria,4NS95@976|Bacteroidetes,2FTZE@200643|Bacteroidia,22YMX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
k59_1386042_1	717605.Theco_3356	4.09e-27	115.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,4HDFB@91061|Bacilli,26RVF@186822|Paenibacillaceae	91061|Bacilli	G	Alpha-L-rhamnosidase	ramA	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
k59_484151_1	504487.JCM19302_1225	8.55e-53	170.0	COG3584@1|root,COG3584@2|Bacteria,4NSKX@976|Bacteroidetes,1I48D@117743|Flavobacteriia	976|Bacteroidetes	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_484151_2	1392490.JHZX01000001_gene3007	1.07e-54	176.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_484151_3	1380600.AUYN01000012_gene2990	3.85e-25	103.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k59_1332433_1	90814.KL370892_gene2224	4.6e-137	395.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,4601X@72273|Thiotrichales	72273|Thiotrichales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_369665_1	411154.GFO_3178	2.8e-108	325.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_9
k59_934092_2	572480.Arnit_2863	1.04e-38	140.0	COG3014@1|root,COG3014@2|Bacteria,1PKX6@1224|Proteobacteria,42PQ4@68525|delta/epsilon subdivisions,2YNQM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k59_934096_1	40215.BBOS01000153_gene2617	2.52e-17	79.7	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,3NIQD@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_1557695_1	411154.GFO_2333	3.02e-119	363.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1209578_1	411154.GFO_1767	1.04e-114	332.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_1209578_2	411154.GFO_1766	2.67e-29	116.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_316641_2	1121015.N789_00210	1.1e-18	84.3	COG3937@1|root,COG3937@2|Bacteria,1N1EW@1224|Proteobacteria,1SDB2@1236|Gammaproteobacteria,1X717@135614|Xanthomonadales	135614|Xanthomonadales	S	Poly(hydroxyalcanoate) granule associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
k59_1617103_1	62928.azo0821	3.45e-122	370.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_1557712_1	869213.JCM21142_104051	1.44e-77	248.0	COG1846@1|root,COG2865@1|root,COG1846@2|Bacteria,COG2865@2|Bacteria,4NGFJ@976|Bacteroidetes,47T5E@768503|Cytophagia	976|Bacteroidetes	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
k59_655633_2	929558.SMGD1_2186	1.04e-57	190.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2YMWU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent	orf1	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1049793_1	1178825.ALIH01000001_gene2400	3.21e-141	400.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1HXZG@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_1049793_2	1380600.AUYN01000006_gene533	7.44e-143	415.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1HXSS@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
k59_880972_1	504487.JCM19302_1724	8.65e-46	151.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_880972_2	1178825.ALIH01000002_gene1023	5.72e-32	121.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1HXAF@117743|Flavobacteriia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1503364_1	572480.Arnit_1609	5.71e-57	192.0	COG0642@1|root,COG2205@2|Bacteria,1RK25@1224|Proteobacteria,42T3D@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_90822_1	1565129.JSFF01000005_gene2318	9.29e-77	244.0	COG1639@1|root,COG2203@1|root,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,1RQ9J@1236|Gammaproteobacteria,2QB1K@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HDOD,Pkinase
k59_936008_1	1565129.JSFF01000004_gene3179	2.57e-90	279.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,2QA4Q@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	bepA	GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_880988_1	1122603.ATVI01000010_gene1071	2.6e-22	99.8	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,1RN4U@1236|Gammaproteobacteria,1X5C7@135614|Xanthomonadales	135614|Xanthomonadales	O	Heat shock protein	yegD	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k59_371825_1	234831.PSM_A1741	1.96e-09	56.2	2DN4U@1|root,32VHV@2|Bacteria,1NDP9@1224|Proteobacteria,1SQ1Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_371825_2	929558.SMGD1_2430	5.24e-52	174.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2YMRT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_32116_1	203122.Sde_0798	6.01e-11	69.3	COG0747@1|root,COG2356@1|root,COG2911@1|root,COG2982@1|root,COG3210@1|root,COG3506@1|root,COG3637@1|root,COG0747@2|Bacteria,COG2356@2|Bacteria,COG2911@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,1P8N9@1224|Proteobacteria,1SCTK@1236|Gammaproteobacteria,46D2E@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,DUF5122,He_PIG,OmpA_membrane
k59_1785857_2	572480.Arnit_1793	2.39e-30	120.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YR6J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k59_1276117_1	504487.JCM19302_2989	3.97e-164	482.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,1HXNB@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
k59_338476_1	1123518.ARWI01000001_gene476	1.41e-38	137.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,461NB@72273|Thiotrichales	72273|Thiotrichales	S	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_338476_2	1123518.ARWI01000001_gene477	1.48e-119	348.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,461WD@72273|Thiotrichales	72273|Thiotrichales	S	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_1693894_1	563040.Saut_2152	8.61e-163	462.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2YN3J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_112951_1	313598.MED152_06960	6.25e-110	330.0	COG4461@1|root,COG4461@2|Bacteria,4NIBZ@976|Bacteroidetes,1I0CW@117743|Flavobacteriia	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PliI
k59_1010723_1	1484460.JSWG01000009_gene458	7.69e-52	164.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
k59_1010723_2	1380600.AUYN01000006_gene530	3.66e-100	295.0	COG1280@1|root,COG1280@2|Bacteria,4NRV8@976|Bacteroidetes,1HY8C@117743|Flavobacteriia	976|Bacteroidetes	E	Pfam LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_1230210_1	1121912.AUHD01000006_gene1211	1.89e-14	70.5	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1HXN2@117743|Flavobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_1230210_2	1380600.AUYN01000006_gene789	6.29e-80	240.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_1230212_1	326442.PSHAb0472	1.02e-12	74.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q01G@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg
k59_1578379_1	1565129.JSFF01000001_gene1201	7.06e-122	366.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,2QB30@267890|Shewanellaceae	1236|Gammaproteobacteria	F	PFAM formate C-acetyltransferase glycine radical	nrdD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454	ATP-cone,NRDD
k59_1578390_1	1172190.M947_07335	1.63e-49	168.0	COG2897@1|root,COG2897@2|Bacteria,1P6SN@1224|Proteobacteria,42VHJ@68525|delta/epsilon subdivisions,2YQHF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_561758_1	411154.GFO_1035	1e-34	126.0	COG1597@1|root,COG1597@2|Bacteria,4NJ68@976|Bacteroidetes,1HZC0@117743|Flavobacteriia	976|Bacteroidetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_acc,DAGK_cat
k59_561758_2	411154.GFO_1036	3.4e-188	526.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,1HZGF@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
k59_617530_1	1123514.KB905899_gene482	6.84e-43	156.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,460M8@72273|Thiotrichales	72273|Thiotrichales	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_901544_1	398767.Glov_1560	3.75e-08	58.9	COG3290@1|root,COG4585@1|root,COG3290@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,HisKA_2,HisKA_3,HisKA_7TM,MASE3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_3,sCache_3_3
k59_1010790_2	1123518.ARWI01000001_gene72	5.65e-91	285.0	COG0428@1|root,COG2905@1|root,COG0428@2|Bacteria,COG2905@2|Bacteria,1QE6Q@1224|Proteobacteria,1S080@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	cNMP_binding
k59_617554_1	90814.KL370891_gene939	6.06e-146	438.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,45ZTQ@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_8,RnfC_N,SLBB
k59_1465736_1	1168067.JAGP01000001_gene1239	1.13e-06	48.9	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46014@72273|Thiotrichales	72273|Thiotrichales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_1465736_2	1123514.KB905899_gene1603	2.03e-150	431.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,4602Q@72273|Thiotrichales	72273|Thiotrichales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_52496_1	439235.Dalk_0037	1.28e-13	73.9	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_677627_1	1123228.AUIH01000008_gene2371	3.57e-91	276.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1XJ9R@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
k59_1184589_1	317025.Tcr_0553	2.7e-34	130.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461EP@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,MCPsignal,PAS_3,PAS_8,PAS_9
k59_450248_1	572480.Arnit_1945	3.23e-102	319.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	histidine kinase HAMP region domain protein	mcp36H	-	-	ko:K03406,ko:K05875,ko:K13487	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal,dCache_1,dCache_2,sCache_2
k59_1010834_1	563040.Saut_2141	3.29e-100	308.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2YMWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
k59_1578506_1	203122.Sde_3474	5.88e-19	87.4	COG0714@1|root,COG1196@1|root,COG0714@2|Bacteria,COG1196@2|Bacteria,1NSN5@1224|Proteobacteria,1RPNN@1236|Gammaproteobacteria,465W9@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
k59_1578506_2	1004785.AMBLS11_17195	2.86e-30	112.0	COG0231@1|root,COG0231@2|Bacteria,1NWY9@1224|Proteobacteria,1RQ0N@1236|Gammaproteobacteria,466J5@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	COG0231 Translation elongation factor P (EF-P) translation initiation factor 5A (eIF-5A)	yeiP	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_561858_1	1406840.Q763_09725	2.42e-76	254.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,1HZXU@117743|Flavobacteriia,2NTUX@237|Flavobacterium	976|Bacteroidetes	L	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
k59_561858_2	655815.ZPR_3457	4.98e-62	191.0	293NS@1|root,2ZR4G@2|Bacteria,4NP3K@976|Bacteroidetes,1I5KH@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4133)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4133
k59_561858_3	655815.ZPR_3458	2e-22	95.1	COG3451@1|root,COG3451@2|Bacteria,4NER7@976|Bacteroidetes,1HWN6@117743|Flavobacteriia	976|Bacteroidetes	U	conjugation system ATPase, TraG family	-	-	-	-	-	-	-	-	-	-	-	-	CagE_TrbE_VirB,DUF3875
k59_1230341_1	1278309.KB907108_gene1550	5.39e-54	182.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XJ1X@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_225224_1	1121931.AUHG01000011_gene2252	6.41e-80	241.0	COG2197@1|root,COG2197@2|Bacteria,4NN4D@976|Bacteroidetes,1I1NU@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_225224_2	1121931.AUHG01000011_gene2253	1.92e-38	139.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k59_393552_1	660470.Theba_1763	4.13e-07	58.5	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,2GCEU@200918|Thermotogae	200918|Thermotogae	T	PFAM GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12
k59_393552_2	1123326.JFBL01000006_gene1003	3.65e-08	53.5	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2YMXB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_166967_1	945713.IALB_3193	8.76e-83	253.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_677699_1	483216.BACEGG_03707	3.1e-12	70.5	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,2FM9N@200643|Bacteroidia,4AKDF@815|Bacteroidaceae	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
k59_166974_2	1172190.M947_09485	4.77e-67	224.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
k59_1694050_1	1121931.AUHG01000011_gene2268	1.14e-82	253.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1HXG5@117743|Flavobacteriia	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_1694050_2	411154.GFO_2097	1.24e-26	103.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1HXVV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_393568_1	1237149.C900_02179	1.43e-102	308.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47J94@768503|Cytophagia	976|Bacteroidetes	E	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_507608_1	929558.SMGD1_2686	2.06e-114	336.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2YN4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1298065_1	1484460.JSWG01000009_gene130	8.42e-117	352.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,4PKJ5@976|Bacteroidetes,1HY50@117743|Flavobacteriia	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k59_1015705_1	1121931.AUHG01000011_gene1839	7.22e-55	180.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_1015705_2	411154.GFO_2679	2.43e-33	121.0	COG3022@1|root,COG3022@2|Bacteria,4NFP2@976|Bacteroidetes,1HZ6C@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k59_957486_1	244582.JQAK01000022_gene652	2.69e-19	83.2	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1411837_1	1121931.AUHG01000011_gene1736	1.56e-18	82.8	2E4WE@1|root,32ZQI@2|Bacteria,4NURF@976|Bacteroidetes,1I5C9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1411837_2	1121931.AUHG01000011_gene1737	1.22e-44	155.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,1HXDI@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_957496_1	1348583.ATLH01000004_gene3949	1.49e-161	485.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SBBP,SprB
k59_1015741_1	1178825.ALIH01000012_gene1829	2.68e-175	494.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1HWMK@117743|Flavobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_1015741_2	1380600.AUYN01000001_gene2448	2.14e-103	307.0	COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1I02I@117743|Flavobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_957616_1	326298.Suden_0287	2.76e-123	353.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2YMU6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_957616_2	563040.Saut_0217	1.2e-57	179.0	COG0089@1|root,COG0089@2|Bacteria,1QJHM@1224|Proteobacteria,42TRQ@68525|delta/epsilon subdivisions,2YPUJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_957616_3	563040.Saut_0218	3.36e-185	516.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2YN0T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_957616_4	387092.NIS_0227	1.57e-52	166.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2YPFU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_957650_1	525257.HMPREF0204_14924	1.71e-81	255.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1HWYT@117743|Flavobacteriia,3ZQ00@59732|Chryseobacterium	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_1015915_1	572480.Arnit_2997	1.06e-48	164.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,42XFP@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	MaoC like domain	mch	GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.2.1.148,4.2.1.56	ko:K14449,ko:K18290	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R02491,R05076	RC00730,RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
k59_1015915_2	572480.Arnit_2996	1.12e-65	207.0	COG2301@1|root,COG2301@2|Bacteria,1PZDS@1224|Proteobacteria,42QHJ@68525|delta/epsilon subdivisions,2YR4R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_1235131_1	1121931.AUHG01000016_gene1082	1.47e-30	118.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_1235131_2	1121931.AUHG01000016_gene1081	2.15e-62	208.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_1412083_1	1137281.D778_01724	5.57e-25	106.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
k59_1412083_2	1178825.ALIH01000003_gene2150	4.78e-42	146.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_957747_1	1121931.AUHG01000018_gene1339	3.77e-07	50.8	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_1412113_1	1123518.ARWI01000001_gene741	2.61e-102	304.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,46040@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k59_1016000_1	1178825.ALIH01000010_gene417	6.99e-148	420.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1HWS5@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotide phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_1016000_2	1178825.ALIH01000010_gene418	1.27e-167	481.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_957932_1	945713.IALB_2126	7.64e-23	91.3	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbW	-	2.7.11.1	ko:K04757,ko:K06379,ko:K08282	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_957932_2	1191523.MROS_2852	1.41e-30	115.0	COG0039@1|root,COG0039@2|Bacteria	2|Bacteria	C	L-malate dehydrogenase activity	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1360	Ldh_1_C,Ldh_1_N
k59_1635858_1	1392490.JHZX01000001_gene3182	3.23e-146	424.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1235629_1	1137281.D778_01654	2.96e-86	265.0	COG2819@1|root,COG2819@2|Bacteria,4NGS5@976|Bacteroidetes,1HYN9@117743|Flavobacteriia	976|Bacteroidetes	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
k59_1235629_2	1353276.JADR01000003_gene2664	5.22e-87	268.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_1016454_1	1189620.AJXL01000118_gene2201	1.1e-110	331.0	COG4487@1|root,COG4487@2|Bacteria,4NFX1@976|Bacteroidetes,1HY62@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
k59_56356_1	929558.SMGD1_1232	4.22e-73	224.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2YMH6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth,NMO
k59_56356_2	1172190.M947_02655	4.61e-40	136.0	COG0775@1|root,COG0775@2|Bacteria,1R9VR@1224|Proteobacteria,42RM2@68525|delta/epsilon subdivisions,2YP67@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_958298_1	1565129.JSFF01000005_gene2327	1.47e-107	310.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,2Q9QS@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_1636134_1	1123008.KB905701_gene2175	1.31e-42	157.0	COG4907@1|root,COG4907@2|Bacteria,4NJKC@976|Bacteroidetes,2FWT9@200643|Bacteroidia,22ZTV@171551|Porphyromonadaceae	976|Bacteroidetes	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_958301_1	1565129.JSFF01000034_gene1474	3.18e-50	161.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,1SCWV@1236|Gammaproteobacteria,2QCHU@267890|Shewanellaceae	1236|Gammaproteobacteria	S	FlhB HrpN YscU SpaS Family	flhB2	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k59_958321_1	1168067.JAGP01000001_gene140	7.59e-87	264.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,460JS@72273|Thiotrichales	72273|Thiotrichales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_958321_2	1168067.JAGP01000001_gene139	1.1e-28	112.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,46043@72273|Thiotrichales	72273|Thiotrichales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
k59_56454_1	28072.Nos7524_3016	5.77e-09	61.6	COG1404@1|root,COG2931@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4935@2|Bacteria,1G1I0@1117|Cyanobacteria,1HR7E@1161|Nostocales	1117|Cyanobacteria	OQ	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind,P_proprotein,Peptidase_S8
k59_11831_1	1380600.AUYN01000001_gene2472	1.44e-235	664.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,1HXD0@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_1084596_1	929558.SMGD1_0150	1.32e-50	169.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2YN32@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1084596_2	929558.SMGD1_0149	4.57e-49	171.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2YN0E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the UbiD family	menA	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0396	UbiD
k59_1594538_1	1123518.ARWI01000001_gene416	1.59e-10	59.3	COG0517@1|root,COG0517@2|Bacteria,1N9XF@1224|Proteobacteria,1SD5P@1236|Gammaproteobacteria,461DI@72273|Thiotrichales	72273|Thiotrichales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
k59_1594538_2	317025.Tcr_1387	2.45e-109	316.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,460A6@72273|Thiotrichales	72273|Thiotrichales	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k59_577372_1	90814.KL370891_gene1270	1.56e-118	350.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,4604B@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
k59_350579_1	1121931.AUHG01000019_gene3019	8.23e-52	169.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_350579_2	411154.GFO_2995	8.15e-16	73.9	COG0566@1|root,COG0566@2|Bacteria,4NMEA@976|Bacteroidetes,1I19V@117743|Flavobacteriia	976|Bacteroidetes	J	rRNA methyltransferase	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1029179_1	929558.SMGD1_0602	9.06e-124	362.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2YMCB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_1195028_1	1380600.AUYN01000007_gene3113	1.63e-244	681.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia	976|Bacteroidetes	M	Lytic murein transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1195028_2	985255.APHJ01000021_gene1773	1.83e-30	117.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1HY6H@117743|Flavobacteriia,2P5HD@244698|Gillisia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
k59_294786_3	1121286.AUMT01000001_gene60	4.85e-42	162.0	29FGV@1|root,302EG@2|Bacteria,4PJGH@976|Bacteroidetes,1I8PA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182343_1	1380600.AUYN01000010_gene875	8.31e-12	63.5	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,1HYIV@117743|Flavobacteriia	976|Bacteroidetes	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_182343_2	504487.JCM19302_2948	1.65e-67	207.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia	976|Bacteroidetes	S	Thiol-disulfide oxidoreductase	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
k59_182343_3	1380600.AUYN01000010_gene882	1.2e-172	503.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1HX0J@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k59_1029185_1	1232410.KI421427_gene1303	9.25e-135	405.0	COG0377@1|root,COG0649@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,43S0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoBCD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,Oxidored_q6
k59_1367027_1	1469557.JSWF01000035_gene1062	3.18e-201	565.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan synthetase	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1367027_2	926559.JoomaDRAFT_2098	0.0	991.0	COG3228@1|root,COG3228@2|Bacteria,4NG95@976|Bacteroidetes,1HXW0@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the MtfA family	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
k59_1367027_3	1121875.KB907549_gene1714	4.3e-51	170.0	28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1481034_1	1100720.ALKN01000007_gene2830	8.26e-10	61.6	COG1075@1|root,COG1075@2|Bacteria,1QXAM@1224|Proteobacteria,2WH3Y@28216|Betaproteobacteria,4AFQU@80864|Comamonadaceae	28216|Betaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1481034_2	317025.Tcr_1166	1.89e-09	54.3	COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007049,GO:0007346,GO:0008150,GO:0009987,GO:0010564,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032465,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051726,GO:0061640,GO:0065007,GO:0071840,GO:0071944,GO:0090529,GO:1901891,GO:1902410,GO:1902412,GO:1903047,GO:1903436	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k59_1195044_1	1380600.AUYN01000010_gene842	2.32e-56	195.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1195044_2	1380600.AUYN01000010_gene841	2.25e-77	254.0	COG1196@1|root,COG3064@1|root,COG1196@2|Bacteria,COG3064@2|Bacteria,4NGJZ@976|Bacteroidetes,1HY5X@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	sprD	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF,SPOR
k59_1650691_1	1205753.A989_11159	2.36e-15	85.5	COG2831@1|root,COG2831@2|Bacteria,1MXF6@1224|Proteobacteria,1RP05@1236|Gammaproteobacteria,1XCMS@135614|Xanthomonadales	135614|Xanthomonadales	U	Hemolysin activation secretion protein	fhaC	-	-	ko:K07326	ko05133,map05133	-	-	-	ko00000,ko00001	-	-	-	POTRA_2,POTRA_3,ShlB
k59_1650691_2	1301098.PKB_3833	0.000937	43.1	COG3210@1|root,COG3210@2|Bacteria,1NWZV@1224|Proteobacteria,1SP31@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG3210 Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Haemagg_act
k59_407838_1	1380600.AUYN01000009_gene1926	1.06e-125	367.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,4NHAG@976|Bacteroidetes,1HWZK@117743|Flavobacteriia	976|Bacteroidetes	ET	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
k59_803523_1	1121931.AUHG01000010_gene829	2.19e-138	403.0	COG2124@1|root,COG2124@2|Bacteria,4NG9Z@976|Bacteroidetes,1HY9E@117743|Flavobacteriia	976|Bacteroidetes	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
k59_1763805_1	983544.Lacal_1084	3.93e-34	126.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1HXG0@117743|Flavobacteriia	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k59_1763805_2	1137281.D778_01903	2.2e-206	573.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_1538290_2	1347342.BN863_34230	6.99e-54	181.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_579083_1	1211817.CCAT010000044_gene3384	1.2e-12	73.9	COG0745@1|root,COG0745@2|Bacteria,1UFB5@1239|Firmicutes,24DDX@186801|Clostridia,36HTK@31979|Clostridiaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_13266_1	387093.SUN_0477	5.85e-158	451.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2YMEX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0183	SHMT
k59_1256182_2	929558.SMGD1_0396	4.66e-49	173.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_1482770_1	1121931.AUHG01000010_gene545	1.78e-83	263.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1HXD1@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k59_1482770_2	411154.GFO_3518	3.26e-185	522.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_70943_1	391603.FBALC1_02152	9.57e-38	144.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4PKKM@976|Bacteroidetes,1HYM7@117743|Flavobacteriia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_70943_2	745718.JADT01000007_gene2791	2.28e-48	157.0	COG3437@1|root,COG3437@2|Bacteria,4NPGE@976|Bacteroidetes,1I23D@117743|Flavobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_13288_1	1178825.ALIH01000007_gene1607	2.28e-26	99.8	COG3759@1|root,COG3759@2|Bacteria,4NQA8@976|Bacteroidetes,1I2SZ@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
k59_13288_2	1137281.D778_02169	1.34e-137	395.0	COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,1HXEP@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_13288_3	504487.JCM19302_1535	7.84e-43	145.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k59_1596252_1	563040.Saut_0215	1.64e-120	345.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2YMFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_296493_1	1244531.CIG1485E_0639	4.55e-12	75.1	COG0840@1|root,COG0840@2|Bacteria,1PDTE@1224|Proteobacteria,42RTH@68525|delta/epsilon subdivisions,2YP7D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Double sensory domain of two-component sensor kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	dCache_3
k59_296493_2	1123518.ARWI01000001_gene1385	4.15e-102	303.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,4603J@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_13291_1	1286632.P278_25250	3.6e-84	258.0	COG1893@1|root,COG1893@2|Bacteria,4NMFF@976|Bacteroidetes,1I3H3@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_1482793_1	1121931.AUHG01000011_gene1989	3.18e-166	503.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_805115_2	1137281.D778_01763	9.72e-151	426.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1HWRQ@117743|Flavobacteriia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k59_805115_3	1469557.JSWF01000028_gene2872	1.84e-48	160.0	2E4I5@1|root,32ZD8@2|Bacteria,4NV9B@976|Bacteroidetes,1I50D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1538349_1	1122225.AULQ01000009_gene375	1.16e-102	298.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1HZQ3@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_1538349_2	1249975.JQLP01000005_gene1538	3.02e-53	181.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA_1	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_1538349_3	391603.FBALC1_04882	1.99e-11	62.8	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,1HXQV@117743|Flavobacteriia	976|Bacteroidetes	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_70972_1	945713.IALB_0912	2.91e-27	104.0	COG0087@1|root,COG0087@2|Bacteria	2|Bacteria	J	rRNA binding	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_70972_2	945713.IALB_0913	1.79e-89	267.0	COG0088@1|root,COG0088@2|Bacteria	2|Bacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02926,ko:K16193	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_1482809_1	983544.Lacal_0300	4.14e-105	322.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1HYRA@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4
k59_1142900_2	1123518.ARWI01000001_gene1523	5.45e-74	241.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales	72273|Thiotrichales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_71000_1	1380600.AUYN01000007_gene3148	4.04e-108	326.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1HYZ4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_240508_2	323850.Shew_2456	4.15e-105	331.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,2Q8KA@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM SMC domain protein	sbcC	GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576,GO:1990238	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
k59_805157_1	1244528.CFT03427_0838	3.25e-12	68.2	COG0642@1|root,COG0642@2|Bacteria,1QUJA@1224|Proteobacteria,42MZ2@68525|delta/epsilon subdivisions,2YN1R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_805157_2	1172190.M947_01370	4.48e-34	119.0	COG2010@1|root,COG2010@2|Bacteria,1QA9H@1224|Proteobacteria,42VAH@68525|delta/epsilon subdivisions,2YQGU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747973_1	1392498.JQLH01000001_gene3726	0.0	972.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia,2PGHH@252356|Maribacter	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_747973_2	983544.Lacal_0835	1.7e-62	207.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1HY1A@117743|Flavobacteriia	976|Bacteroidetes	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
k59_352274_1	572480.Arnit_0461	5.86e-79	242.0	COG2010@1|root,COG2010@2|Bacteria,1PDTK@1224|Proteobacteria,42N5Z@68525|delta/epsilon subdivisions,2YMTR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_352274_2	563040.Saut_1961	1.25e-16	74.3	2AIVC@1|root,32MS0@2|Bacteria,1Q3D2@1224|Proteobacteria,42X4G@68525|delta/epsilon subdivisions,2YQTS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Family of unknown function (DUF4006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4006
k59_71012_1	411154.GFO_3087	2.29e-09	60.1	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_71012_2	1122226.AUHX01000006_gene2225	1.17e-32	126.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1652476_1	387093.SUN_1117	1.65e-21	88.6	2BKM9@1|root,32F2P@2|Bacteria,1Q555@1224|Proteobacteria,430JV@68525|delta/epsilon subdivisions,2YS2S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_1652476_2	563040.Saut_1738	6.29e-131	380.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_1256299_1	1123514.KB905899_gene982	3.35e-91	276.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,460K7@72273|Thiotrichales	72273|Thiotrichales	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_1256299_2	1123518.ARWI01000001_gene179	1.35e-120	347.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,460FH@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k59_1256299_3	1123514.KB905899_gene984	1.03e-18	81.6	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_409596_1	746697.Aeqsu_0604	1.85e-148	422.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1HYS0@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
k59_409596_2	985255.APHJ01000054_gene1989	2.76e-44	145.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1I2TQ@117743|Flavobacteriia,2P7KH@244698|Gillisia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_579215_1	1380600.AUYN01000001_gene2371	2.31e-252	717.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1142959_1	1121904.ARBP01000012_gene1293	4.28e-141	430.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria	2|Bacteria	P	domain protein	yjbQ	-	-	ko:K03455,ko:K03499	-	-	-	-	ko00000,ko02000	2.A.37,2.A.38.1,2.A.38.4	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_1256312_1	572480.Arnit_0001	4.84e-29	113.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1256312_2	572480.Arnit_3150	1.09e-56	180.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_1086313_1	411154.GFO_0145	8.6e-140	425.0	COG0477@1|root,COG0477@2|Bacteria,4PM7N@976|Bacteroidetes,1IJKR@117743|Flavobacteriia	976|Bacteroidetes	EGP	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
k59_1314104_1	1219072.VHA01S_029_00020	1.33e-37	140.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XSBV@135623|Vibrionales	135623|Vibrionales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_972209_1	317025.Tcr_2159	4.06e-25	103.0	COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,1S1UE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k59_972209_2	1123514.KB905902_gene243	4.39e-74	225.0	COG1416@1|root,COG1416@2|Bacteria,1RKXJ@1224|Proteobacteria,1S6P0@1236|Gammaproteobacteria,462TC@72273|Thiotrichales	72273|Thiotrichales	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_972209_3	1123518.ARWI01000001_gene1407	2.46e-09	55.5	COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,4633S@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_1086316_1	326298.Suden_1163	7.19e-214	617.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2YMFT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1652520_1	411154.GFO_2074	2.74e-66	202.0	2ADBR@1|root,31316@2|Bacteria,4NQ7M@976|Bacteroidetes,1I2VQ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2853
k59_240578_1	546266.NEIMUCOT_04880	1.11e-17	82.8	COG0842@1|root,COG1131@1|root,COG3845@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG3845@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria,2KQBY@206351|Neisseriales	206351|Neisseriales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_tran
k59_240578_2	1267005.KB911259_gene4085	1.6e-52	176.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2TTRG@28211|Alphaproteobacteria,3N90C@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1256321_1	1249997.JHZW01000002_gene777	5.27e-05	44.3	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia,2PI7U@252356|Maribacter	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
k59_1256321_2	745718.JADT01000002_gene2323	7.42e-155	442.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_1256321_3	1137281.D778_02752	3.21e-185	523.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_240581_1	749222.Nitsa_1483	1.98e-52	183.0	COG0642@1|root,COG0642@2|Bacteria,1QUJA@1224|Proteobacteria,42MZ2@68525|delta/epsilon subdivisions,2YN1R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	dccS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_184192_1	319236.JCM19294_1846	5.67e-67	212.0	COG3047@1|root,COG3047@2|Bacteria,4PJX2@976|Bacteroidetes,1IMX1@117743|Flavobacteriia,3HMAG@363408|Nonlabens	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
k59_1496919_1	1165841.SULAR_05028	2.81e-87	268.0	COG0677@1|root,COG0677@2|Bacteria,1QV0P@1224|Proteobacteria,43BN8@68525|delta/epsilon subdivisions,2YNJZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_761218_1	323850.Shew_3076	5.46e-45	150.0	COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,2QACQ@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_1099803_1	387093.SUN_1735	2.91e-66	226.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2YNN5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
k59_254815_1	4513.MLOC_62375.5	8.04e-16	82.4	COG1593@1|root,KOG3018@2759|Eukaryota,37SG1@33090|Viridiplantae,3GEJ7@35493|Streptophyta,3KTGD@4447|Liliopsida,3ICC4@38820|Poales	35493|Streptophyta	G	Malonyl-CoA decarboxylase C-terminal domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009154,GO:0009165,GO:0009166,GO:0009259,GO:0009260,GO:0009261,GO:0009893,GO:0009987,GO:0010565,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019216,GO:0019217,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031323,GO:0031325,GO:0031974,GO:0033865,GO:0033866,GO:0033869,GO:0033875,GO:0034030,GO:0034031,GO:0034032,GO:0034033,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0035384,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045834,GO:0045923,GO:0046320,GO:0046321,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0048518,GO:0048522,GO:0050080,GO:0050789,GO:0050794,GO:0051186,GO:0051188,GO:0055086,GO:0062012,GO:0062013,GO:0065007,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0080090,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:2001293,GO:2001294	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
k59_1779828_1	1121931.AUHG01000011_gene1934	2.24e-101	297.0	COG1280@1|root,COG1280@2|Bacteria,4NEG3@976|Bacteroidetes,1HYBH@117743|Flavobacteriia	976|Bacteroidetes	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_1779828_2	929556.Solca_2357	3.17e-19	85.1	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1382061_1	1121931.AUHG01000010_gene451	3.18e-120	357.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,1HXWR@117743|Flavobacteriia	976|Bacteroidetes	G	Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k59_649376_1	1197477.IA57_11400	1.51e-32	115.0	2EHT5@1|root,32ZJC@2|Bacteria,4NVEE@976|Bacteroidetes,1I5FZ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4834)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4834
k59_423227_1	1121931.AUHG01000010_gene72	7.29e-105	306.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1I0I9@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_423227_2	1111730.ATTM01000003_gene447	0.000747	42.4	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia,2NSB2@237|Flavobacterium	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_197846_1	411154.GFO_2345	6.14e-95	298.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXPB@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k59_310400_2	945713.IALB_1400	1.07e-21	96.3	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	ASH,CBM_2,Calx-beta,DUF4214,FlgD_ig,HemolysinCabind,SdrD_B
k59_1382094_1	1178825.ALIH01000003_gene2076	1.57e-33	120.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_1382094_2	1178825.ALIH01000003_gene2077	1.45e-186	523.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_1382094_3	1178825.ALIH01000003_gene2078	1.19e-06	50.4	2E0H2@1|root,32W2Y@2|Bacteria,4NT2B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_930633_1	504487.JCM19302_3889	9.32e-52	187.0	COG1345@1|root,COG1345@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_930633_2	504487.JCM19302_3887	1.08e-08	54.3	2C260@1|root,33GRW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_26528_1	1121007.AUML01000014_gene2869	1.78e-75	228.0	COG1959@1|root,COG1959@2|Bacteria,4NPHI@976|Bacteroidetes,1I2QC@117743|Flavobacteriia,2YI3T@290174|Aquimarina	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_311782_1	1123514.KB905899_gene456	6.61e-138	399.0	COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,1RP1W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
k59_311782_2	90813.JQMT01000001_gene425	2.85e-09	57.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,461ZR@72273|Thiotrichales	72273|Thiotrichales	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
k59_1498430_1	944547.ABLL_0443	1.49e-119	359.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2YMTF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1329745_1	1121931.AUHG01000019_gene2975	1.03e-86	264.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1HWR8@117743|Flavobacteriia	976|Bacteroidetes	E	fad dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1329745_2	411154.GFO_3012	1.05e-44	152.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
k59_1440370_1	572480.Arnit_2293	3.86e-53	175.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
k59_1440370_2	572480.Arnit_2292	9.32e-73	234.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2YNFI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COGs COG0069 Glutamate synthase domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k59_1271428_1	572480.Arnit_1261	4.23e-93	277.0	COG0730@1|root,COG0730@2|Bacteria,1RJXP@1224|Proteobacteria,42UVE@68525|delta/epsilon subdivisions,2YQ2B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_709335_1	572480.Arnit_0937	3.37e-160	451.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,42P3X@68525|delta/epsilon subdivisions,2YN2A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k59_86182_1	317025.Tcr_1144	3.03e-115	337.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,4609T@72273|Thiotrichales	72273|Thiotrichales	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1440385_1	929558.SMGD1_1033	5.48e-72	222.0	COG4221@1|root,COG4221@2|Bacteria,1QVCA@1224|Proteobacteria,43D38@68525|delta/epsilon subdivisions,2YTFY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1440385_2	929558.SMGD1_1034	3.06e-24	94.0	29KSI@1|root,307PY@2|Bacteria,1PX63@1224|Proteobacteria,433IG@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_537509_1	1353528.DT23_04570	1.07e-46	160.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,2XKRV@285107|Thioclava	28211|Alphaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_537509_2	1353537.TP2_02190	7.3e-50	158.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,2XNHX@285107|Thioclava	28211|Alphaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_1667536_1	938709.AUSH02000035_gene1468	1.24e-54	172.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1667536_2	1469557.JSWF01000014_gene2618	2.38e-72	225.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_1329781_1	1232410.KI421413_gene609	1.46e-104	313.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,43TWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k59_932001_1	326298.Suden_1093	5.43e-38	138.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,42MHI@68525|delta/epsilon subdivisions,2YMU8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k59_932001_2	563040.Saut_1205	5.66e-34	120.0	COG4786@1|root,COG4786@2|Bacteria,1NC8Z@1224|Proteobacteria,42XCU@68525|delta/epsilon subdivisions,2YQV6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_932001_3	929558.SMGD1_2720	0.000246	42.7	COG0791@1|root,COG0791@2|Bacteria,1R45H@1224|Proteobacteria,42NS0@68525|delta/epsilon subdivisions,2YN06@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,N_NLPC_P60,Peptidase_M15_4,SH3_6,SH3_7
k59_650860_1	66869.JNXG01000002_gene5588	1.06e-24	107.0	COG5297@1|root,COG5297@2|Bacteria,2GMQN@201174|Actinobacteria,41BZ1@629295|Streptomyces griseus group	201174|Actinobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_4_9,CelD_N,Glyco_hydro_9
k59_1724031_1	259536.Psyc_1409	2.95e-23	89.7	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,3NPBC@468|Moraxellaceae	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_1724031_2	1123514.KB905899_gene850	2.03e-113	347.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent Clp protease ATP-binding subunit ClpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1612381_1	985255.APHJ01000019_gene754	8.68e-243	704.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2P78E@244698|Gillisia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_1612381_2	985255.APHJ01000019_gene755	5.91e-15	74.7	COG3193@1|root,COG3193@2|Bacteria,4NGTI@976|Bacteroidetes,1HWKH@117743|Flavobacteriia,2P7PZ@244698|Gillisia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_1724033_1	62928.azo2137	1.75e-19	84.7	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2VHM4@28216|Betaproteobacteria,2KUB4@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k59_1724033_2	62928.azo1913	5.59e-35	132.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,2KV32@206389|Rhodocyclales	206389|Rhodocyclales	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like
k59_311841_1	1121875.KB907547_gene3136	1.1e-155	472.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1HXEG@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_311841_2	1121875.KB907547_gene3135	2.63e-46	152.0	2EDMN@1|root,337HG@2|Bacteria,4NWVI@976|Bacteroidetes,1I9SP@117743|Flavobacteriia	976|Bacteroidetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
k59_311841_3	983544.Lacal_1296	4.08e-43	141.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1I3YF@117743|Flavobacteriia	976|Bacteroidetes	O	Nitrogen fixation protein NifU	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_311841_4	1178825.ALIH01000001_gene2404	1.64e-135	393.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_141417_1	1121931.AUHG01000010_gene321	6.23e-126	368.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1I0Z8@117743|Flavobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,MarR,ROK
k59_424684_1	326298.Suden_1053	2.17e-56	185.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2YMD2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_424684_2	326298.Suden_1054	1.09e-84	255.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2YMMW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Oxidoreductase	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_984296_1	572480.Arnit_0068	8.97e-58	190.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,42P89@68525|delta/epsilon subdivisions,2YN9D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k59_984296_2	572480.Arnit_0067	3.85e-69	210.0	COG2077@1|root,COG2077@2|Bacteria	2|Bacteria	O	thioredoxin peroxidase activity	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k59_984296_3	572480.Arnit_0066	4.02e-30	111.0	COG2077@1|root,COG2077@2|Bacteria,1Q5WV@1224|Proteobacteria,431ZJ@68525|delta/epsilon subdivisions,2YSAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_1271490_1	1380600.AUYN01000009_gene1916	1.45e-52	185.0	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,1I0PP@117743|Flavobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_256398_1	1123514.KB905902_gene232	1.3e-25	104.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,460QI@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_256398_2	90814.KL370892_gene2289	7.73e-13	66.6	2C5QF@1|root,331W9@2|Bacteria,1N7AE@1224|Proteobacteria,1SCH2@1236|Gammaproteobacteria,463UG@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
k59_1553164_1	497321.C664_12625	9.75e-151	444.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,2KV3G@206389|Rhodocyclales	206389|Rhodocyclales	E	COG1982 Arginine lysine ornithine decarboxylases	adiA	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
k59_481809_2	1172190.M947_05330	3.47e-56	189.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2YMSH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_537552_1	563040.Saut_1217	1.02e-261	730.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2YMMT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_141440_1	1121931.AUHG01000017_gene1525	8.17e-134	390.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
k59_1553172_1	1121931.AUHG01000010_gene115	7.16e-50	158.0	2E389@1|root,32Y7Y@2|Bacteria,4NW5R@976|Bacteroidetes,1I5BX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_27927_1	1123367.C666_04145	1.52e-70	218.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,2KW3W@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_27927_2	522306.CAP2UW1_1111	2.1e-08	52.8	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,1KQ3H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_821233_1	929558.SMGD1_2819	5.89e-135	410.0	COG0419@1|root,COG0419@2|Bacteria,1Q57D@1224|Proteobacteria,42NIY@68525|delta/epsilon subdivisions,2YNHQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	P-loop containing region of AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_1329861_1	1236542.BALM01000016_gene1371	2.7e-14	77.8	COG2200@1|root,COG2200@2|Bacteria,1NTQU@1224|Proteobacteria,1SMGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k59_1157966_1	1336233.JAEH01000018_gene3065	4.12e-29	112.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,2Q964@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
k59_1157966_2	1565129.JSFF01000002_gene3565	1.29e-182	509.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,2QA5G@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1157966_3	323850.Shew_0878	9.68e-16	71.6	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,2QC8F@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k59_1101370_1	1122212.AULO01000008_gene1260	5.66e-83	264.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1R5X9@1224|Proteobacteria,1RZQT@1236|Gammaproteobacteria,1XM2F@135619|Oceanospirillales	135619|Oceanospirillales	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k59_1329875_1	62928.azo3642	3.57e-92	300.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KUPX@206389|Rhodocyclales	206389|Rhodocyclales	E	glutamate synthase	gls1	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_86289_1	497321.C664_09778	3.38e-119	356.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VKMW@28216|Betaproteobacteria,2KV2G@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly-beta-hydroxybutyrate	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k59_709480_1	1168067.JAGP01000001_gene1771	6.32e-64	209.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1QVHK@1224|Proteobacteria,1T2M2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k59_709480_2	317025.Tcr_0413	4.14e-16	76.6	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1T9PX@1236|Gammaproteobacteria,461QG@72273|Thiotrichales	72273|Thiotrichales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_1045861_1	504487.JCM19302_3907	1.58e-46	161.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1045861_2	1178825.ALIH01000003_gene2029	7.07e-67	224.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_367272_1	929556.Solca_0777	2.66e-88	278.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IPQT@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_1206851_1	929558.SMGD1_1246	1.36e-08	53.5	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_1206851_2	1172190.M947_02580	8.09e-73	231.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2YM88@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1498617_1	572480.Arnit_2253	9.42e-94	287.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2YMVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	FP	Guanosine pentaphosphate phosphohydrolase	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_1329912_1	565045.NOR51B_2776	1.86e-123	367.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1J8GB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_1553256_1	1178825.ALIH01000014_gene1977	4.1e-91	291.0	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,1HZGN@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_256504_1	876269.ARWA01000001_gene3680	3.52e-12	65.5	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,3N9UN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_481916_1	1123514.KB905899_gene1540	3.57e-57	185.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,460D3@72273|Thiotrichales	72273|Thiotrichales	EH	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k59_481916_2	1123514.KB905899_gene1539	4.62e-08	53.5	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4602E@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_1271604_1	323850.Shew_1985	3.79e-69	221.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,2Q905@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_327992_2	1178825.ALIH01000004_gene2855	8.86e-99	292.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1HZSH@117743|Flavobacteriia	976|Bacteroidetes	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_1346193_1	331869.BAL199_29485	3.96e-11	63.5	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,4BPJ2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Carboxyl transferase domain	mccB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_1346193_2	1123228.AUIH01000010_gene3993	4.81e-60	196.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XI78@135619|Oceanospirillales	135619|Oceanospirillales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_382925_1	411154.GFO_2667	2.12e-91	270.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,1I1TM@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_891572_1	504487.JCM19302_4100	6.85e-09	56.6	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_891572_2	504487.JCM19302_4101	8.04e-64	199.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_158916_2	497321.C664_08528	8.23e-109	316.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,2KUB9@206389|Rhodocyclales	206389|Rhodocyclales	S	Phospholipid-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k59_1062242_1	411154.GFO_1778	3.38e-65	212.0	COG0745@1|root,COG0745@2|Bacteria,4PM6N@976|Bacteroidetes,1IJMR@117743|Flavobacteriia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
k59_1062242_2	1121931.AUHG01000017_gene1521	1.79e-18	79.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1I3XP@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_1401120_1	1121931.AUHG01000012_gene2571	1.61e-112	328.0	COG1028@1|root,COG1028@2|Bacteria,4PKM5@976|Bacteroidetes,1HYF7@117743|Flavobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_44799_1	1392490.JHZX01000001_gene177	9.46e-41	148.0	COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia	976|Bacteroidetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
k59_44799_2	1178825.ALIH01000003_gene2232	3.15e-228	640.0	COG3281@1|root,COG3281@2|Bacteria,4PMAP@976|Bacteroidetes,1HZME@117743|Flavobacteriia	976|Bacteroidetes	G	Trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH
k59_1457758_1	1123514.KB905903_gene374	1.15e-44	156.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,4601J@72273|Thiotrichales	72273|Thiotrichales	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1570922_1	326298.Suden_1457	2.85e-122	357.0	28M05@1|root,32SJ0@2|Bacteria,1N115@1224|Proteobacteria,42ZGF@68525|delta/epsilon subdivisions,2YRPD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1221950_1	1336233.JAEH01000013_gene3467	3.52e-77	256.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,2Q95R@267890|Shewanellaceae	1236|Gammaproteobacteria	EKT	PFAM histidine kinase, HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,SBP_bac_3,dCache_1
k59_1517174_1	90814.KL370892_gene1943	1.15e-49	165.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,45ZRW@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_1517174_2	90813.JQMT01000001_gene17	1.55e-55	183.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,460AU@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM A G-specific adenine glycosylase	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_1457775_1	929558.SMGD1_1138	6.77e-65	201.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,42RYN@68525|delta/epsilon subdivisions,2YP3T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_1401155_1	1172190.M947_05970	1.69e-21	92.8	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2YMVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
k59_1401155_2	929558.SMGD1_1520	3.12e-107	335.0	COG2887@1|root,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_1799670_1	655815.ZPR_0565	2.18e-66	211.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1HXT6@117743|Flavobacteriia	976|Bacteroidetes	M	sugar transferase	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k59_1799670_2	1121875.KB907546_gene2394	1.06e-11	66.2	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,1I4DT@117743|Flavobacteriia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_272513_1	1328313.DS2_16034	3.83e-25	95.9	COG2119@1|root,COG2119@2|Bacteria,1N85A@1224|Proteobacteria,1SAAX@1236|Gammaproteobacteria,4690H@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k59_1517187_1	1565129.JSFF01000026_gene1228	1.14e-38	129.0	2CTIP@1|root,32STK@2|Bacteria,1MZ8V@1224|Proteobacteria,1SEQR@1236|Gammaproteobacteria,2QCK0@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1107
k59_1517187_2	225849.swp_2177	3.37e-29	105.0	COG3074@1|root,COG3074@2|Bacteria,1QENT@1224|Proteobacteria,1TBFU@1236|Gammaproteobacteria,2QCVC@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA	zapB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	ZapB
k59_1517187_3	323850.Shew_0270	1.6e-59	188.0	COG3637@1|root,COG3637@2|Bacteria,1RIYQ@1224|Proteobacteria,1S7BE@1236|Gammaproteobacteria,2Q9VT@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	oprH	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k59_1002598_2	1172190.M947_09880	1.78e-67	212.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2YMP6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k59_104826_2	929558.SMGD1_0397	2.33e-28	103.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_104826_3	563040.Saut_0738	6.11e-87	277.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2YN2C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT,HD_4,RelA_SpoT,TGS
k59_330326_1	411154.GFO_0778	1.94e-117	356.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_893707_2	326298.Suden_1089	2.69e-15	70.9	2BSN9@1|root,32MQW@2|Bacteria,1Q3CP@1224|Proteobacteria,42X3U@68525|delta/epsilon subdivisions,2YQYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AF0941-like	-	-	-	-	-	-	-	-	-	-	-	-	AF0941-like
k59_1221996_1	1123514.KB905899_gene1887	2.84e-156	444.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,4605X@72273|Thiotrichales	72273|Thiotrichales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_1742854_1	985255.APHJ01000019_gene755	4.35e-125	374.0	COG3193@1|root,COG3193@2|Bacteria,4NGTI@976|Bacteroidetes,1HWKH@117743|Flavobacteriia,2P7PZ@244698|Gillisia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
k59_442433_1	1209072.ALBT01000023_gene4038	8.66e-33	131.0	COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,1RRXK@1236|Gammaproteobacteria,1FHUR@10|Cellvibrio	1236|Gammaproteobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR,F5_F8_type_C
k59_1289752_1	563040.Saut_0426	1.89e-147	427.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2YMK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	Herpes_Helicase,PIF1
k59_1348616_1	411154.GFO_0652	3.74e-104	317.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_947315_1	90814.KL370892_gene2184	9.42e-63	199.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,45ZXS@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_947315_2	1168067.JAGP01000001_gene2087	8.26e-314	859.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_217614_1	1250005.PHEL85_3150	6.08e-25	104.0	COG1621@1|root,COG4099@1|root,COG1621@2|Bacteria,COG4099@2|Bacteria,4PI4D@976|Bacteroidetes,1IES8@117743|Flavobacteriia,3VXDU@52959|Polaribacter	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_837350_1	1121931.AUHG01000012_gene2798	2.16e-06	46.6	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1I21M@117743|Flavobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k59_837350_2	1121931.AUHG01000012_gene2797	7.54e-66	200.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k59_837350_3	1121931.AUHG01000012_gene2796	1.72e-97	284.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1I202@117743|Flavobacteriia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_385358_1	1380600.AUYN01000007_gene3158	1.07e-17	82.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_385358_2	313590.MED134_09161	3.79e-41	151.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,37DT6@326319|Dokdonia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1517295_1	572480.Arnit_1466	2.09e-59	187.0	COG2731@1|root,COG2731@2|Bacteria,1MZ1I@1224|Proteobacteria,42W5J@68525|delta/epsilon subdivisions,2YQBP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
k59_1517295_2	944546.ABED_0685	4.12e-05	43.9	2BSN9@1|root,32MQW@2|Bacteria,1Q3CP@1224|Proteobacteria,42X3U@68525|delta/epsilon subdivisions,2YQYI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	AF0941-like	-	-	-	-	-	-	-	-	-	-	-	-	AF0941-like
k59_1457879_1	1121931.AUHG01000011_gene2228	0.0	1088.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1HYEX@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
k59_1742956_1	572480.Arnit_0120	1.27e-96	306.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU6Y@1224|Proteobacteria,42M5I@68525|delta/epsilon subdivisions,2YN4K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	D-lactate dehydrogenase	dld	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
k59_609794_2	944547.ABLL_2721	1.31e-49	174.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNN1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1289863_1	563040.Saut_1926	8.24e-94	281.0	COG2010@1|root,COG2857@1|root,COG2010@2|Bacteria,COG2857@2|Bacteria,1PX4N@1224|Proteobacteria,42MFF@68525|delta/epsilon subdivisions,2YMBA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	ubiquinol cytochrome c oxidoreductase, cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	iIT341.HP1538	Cytochrom_C,Cytochrom_C1
k59_1289863_2	326298.Suden_1918	4.26e-07	50.8	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,42UXC@68525|delta/epsilon subdivisions,2YPKG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_1222141_1	1123326.JFBL01000001_gene1368	2.75e-53	179.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2YMXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k59_272648_3	90814.KL370892_gene2202	2.71e-25	100.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,461HI@72273|Thiotrichales	72273|Thiotrichales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_1627443_1	1121931.AUHG01000010_gene440	6.09e-162	493.0	COG0823@1|root,COG4677@1|root,COG5276@1|root,COG0823@2|Bacteria,COG4677@2|Bacteria,COG5276@2|Bacteria,4PNFN@976|Bacteroidetes,1I0J5@117743|Flavobacteriia	976|Bacteroidetes	G	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,TSP_3
k59_781519_1	563040.Saut_1209	7.07e-57	179.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2YP8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_781519_2	929558.SMGD1_2723	9.85e-163	459.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2YMX5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_781519_3	1123326.JFBL01000015_gene2454	4.59e-05	43.5	2B0KG@1|root,31SY5@2|Bacteria,1QAAH@1224|Proteobacteria,42VV8@68525|delta/epsilon subdivisions,2YQW5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159122_1	1121912.AUHD01000001_gene2300	3.27e-47	160.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,1HXRN@117743|Flavobacteriia	976|Bacteroidetes	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_272656_1	746697.Aeqsu_0954	5.12e-134	401.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
k59_442566_1	945713.IALB_0632	1.31e-40	141.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_442566_2	945713.IALB_0633	1.05e-28	109.0	COG1127@1|root,COG1127@2|Bacteria	2|Bacteria	Q	ATPase activity	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_947418_1	90814.KL370891_gene1043	6.49e-64	215.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_947418_2	1123518.ARWI01000001_gene243	2.74e-81	253.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,46052@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_609848_1	572480.Arnit_0233	1.37e-47	156.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	-	-	1.5.1.38	ko:K00299,ko:K11811	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
k59_609848_2	748247.AZKH_2986	3.96e-27	108.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,2KVN7@206389|Rhodocyclales	206389|Rhodocyclales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_609850_1	411154.GFO_0622	4.61e-130	381.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_1289911_1	1380600.AUYN01000009_gene1132	7.81e-221	637.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
k59_947437_1	563040.Saut_2027	1.72e-24	102.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2YNS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	COGs COG0025 NhaP-type Na H and K H antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
k59_947437_2	1172190.M947_02715	1.66e-90	279.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2YMUF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_837447_1	1123228.AUIH01000013_gene219	5.63e-96	296.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XIX9@135619|Oceanospirillales	135619|Oceanospirillales	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_893901_1	225849.swp_4862	2.88e-118	341.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,2QAN1@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	ompR	GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_272695_1	411154.GFO_1970	1.3e-30	121.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k59_272695_2	1121931.AUHG01000011_gene2378	7.04e-10	58.2	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1HWW7@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1062525_1	944546.ABED_1793	2.86e-13	71.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2YR1U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_2,sCache_2
k59_1062525_2	572480.Arnit_1023	2.06e-39	145.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1NU9A@1224|Proteobacteria,42YSZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,dCache_2
k59_45073_1	411154.GFO_0384	3.45e-93	280.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,1HXRN@117743|Flavobacteriia	976|Bacteroidetes	G	fructose-bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_45073_2	1121931.AUHG01000013_gene2462	8.7e-07	49.3	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1HXQR@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_330558_1	1178825.ALIH01000003_gene2174	6.81e-113	333.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_330558_2	1380600.AUYN01000007_gene3240	3.83e-195	555.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
k59_330558_3	1380600.AUYN01000007_gene3241	3.35e-158	472.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
k59_728451_2	1537917.JU82_00855	1.11e-186	528.0	COG0045@1|root,COG0045@2|Bacteria,1PYM0@1224|Proteobacteria,42NR1@68525|delta/epsilon subdivisions,2YMG6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the succinate malate CoA ligase beta subunit family	-	-	2.3.3.8	ko:K15231	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Citrate_bind
k59_385562_1	1035197.HMPREF9999_01780	6.66e-32	124.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,2FPAJ@200643|Bacteroidia,1WCXS@1283313|Alloprevotella	976|Bacteroidetes	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_385562_2	1197477.IA57_01740	5.17e-134	395.0	COG2244@1|root,COG2244@2|Bacteria,4NI85@976|Bacteroidetes,1HXZ7@117743|Flavobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	wzxE	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k59_385563_1	945713.IALB_0415	7.98e-33	132.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217855_1	313603.FB2170_05945	4.04e-19	91.7	COG2373@1|root,COG3209@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PGPS@252356|Maribacter	976|Bacteroidetes	M	C-terminal domain of CHU protein family	sprB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k59_1290000_1	387093.SUN_0275	1.38e-207	607.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YM96@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cmeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
## 16850 queries scanned
## Total time (seconds): 149.70145273208618
## Rate: 112.56 q/s